TWAS hub - CXCR1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	NTR	Blood	0.0264	0.0089	6.3e-06	0.025	0.019	0.021	0.022	0.025	1.2e-08	7.2e-07	2.2e-07	9.5e-08	1.1e-08
2	YFS	Blood	0.1081	0.0203	0.0e+00	0.137	0.127	0.144	0.141	0.140	1.5e-42	3.2e-39	1.3e-44	7.0e-44	2.1e-43

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Ulcerative Colitis	13.2	19.2	21.3	-4.1	-4.6
Irritable Bowel Disease (IBD)	12.9	30.7	34.2	-5.8	-5.2
Ulcerative Colitis (UC)	11.0	20.7	23.4	-4.8	-4.2
Blood Platelet Count	9.7	112.5	127.7	-9.9	-11.3
Had other major operations	7.8	9.6	9.7	3.1	3.1
Height	6.6	126.6	130.0	11.4	11.1
Comparative height size at age 10	6.6	36.4	38.1	6.2	5.9
Pulse wave reflection index	5.7	7.1	7.3	2.7	2.6
Had menopause	5.2	6.5	9.2	1.9	3.0
Standing height	5.2	51.4	53.7	7.3	7.0
Crohns Disease (2017)	4.9	10.7	11.8	-3.4	-3.1
Breast cancer (self-reported)	4.7	5.6	7.6	1.9	2.8
Hayfever/allergic rhinitis (self-reported)	4.6	6.1	6.6	-2.6	-2.4
Trunk fat-free mass	4.5	25.8	29.1	5.4	4.8
Trunk predicted mass	4.4	25.3	28.4	5.3	4.7
Relative age voice broke	4.3	6.5	7.1	-2.7	-2.5
Sitting height	4.2	29.7	31.2	5.6	5.3
Arm predicted mass (left)	4.1	20.6	23.1	4.8	4.2
Illnesses of father: High blood pressure	3.9	4.9	5.4	-2.1	-2.3
Allergy	3.8	8.7	9.1	2.9	3.0
Diabetes (father)	3.7	4.6	6.9	-2.6	-1.5
Eye problems/disorders: Diabetes related eye disease	3.5	3.9	4.5	-1.8	-2.1
Asthma	3.5	6.9	7.1	-2.7	-2.6
Arm fat-free mass (left)	3.4	17.1	18.9	4.3	3.9
Waist Hip Ratio (WHR)	3.3	14.9	15.4	-3.8	-3.9
Alcohol usually taken with meals	3.3	5.3	5.7	2.2	2.4
Forced vital capacity (FVC)	3.3	12.6	14.1	3.8	3.3
Time employed in main current job	3.3	3.8	4.5	1.8	2.1
Allergy or Eczema	3.2	8.3	8.6	-2.8	-2.9
Medication: Cholesterol lowering	3.2	4.9	5.8	-2.0	-2.4
Osteoporosis (self-reported)	3.1	3.9	4.2	2.0	1.9
Hearing aid user	3.1	3.5	3.7	1.8	1.9
Breast Cancer	3.0	7.1	8.3	-2.5	-2.9
Blood White Count	3.0	22.4	27.5	5.2	4.2
Chronic bronchitis/emphysema (mother)	3.0	3.5	4.0	-1.7	-2.0
Forced vital capacity (FVC), Best measure	3.0	11.1	11.6	3.2	3.4
Arm fat-free mass (right)	3.0	15.3	18.0	4.2	3.5
Arm predicted mass (right)	3.0	15.2	17.9	4.2	3.5
Whole body water mass	3.0	16.9	19.6	4.4	3.8
LDL Cholesterol	2.9	4.6	5.1	-2.3	-2.0
Whole body fat-free mass	2.9	16.5	19.1	4.4	3.7
Handedness (chirality/laterality): Left-handed	2.9	3.5	3.8	-1.9	-1.8
Respiratory disease	2.8	6.2	7.0	-2.6	-2.3
Eye problems/disorders: Glaucoma	2.8	3.3	3.9	-1.6	-2.0
Mouth/teeth dental problems	2.7	4.1	4.8	1.9	2.2
Heart attack	2.7	3.4	3.9	-1.7	-2.0
Qualifications: NVQ or HND or HNC or equivalent	2.7	3.3	4.5	-1.4	-2.1
Average weekly red wine intake	2.7	4.0	4.8	2.2	1.8
Asthma (self-reported)	2.7	5.3	5.5	-2.4	-2.2
High cholesterol (Self-reported)	2.7	4.8	5.5	-2.0	-2.3
Ever had prostate specific antigen (PSA) test	2.7	3.1	4.7	1.2	2.2
Basal metabolic rate	2.6	14.1	16.8	4.1	3.4
Hayfever, allergic rhinitis or eczema	2.5	5.5	6.2	-2.2	-2.5
Birth weight of first child	2.5	4.6	5.8	2.4	1.8
Number of operations (self-reported)	2.5	3.7	5.0	2.2	1.5
Lung cancer (father)	2.4	2.8	3.6	1.4	1.9
Gout (self-reported)	2.4	3.3	4.4	-1.5	-2.1
Birth weight	2.4	5.1	6.2	2.0	2.5
Illnesses of siblings: Diabetes	2.4	3.0	3.9	-2.0	-1.5
Heart attack/myocardial infarction (self-reported)	2.3	3.0	3.7	-1.5	-1.9
Alzheimer’s Disease (including proxy)	2.2	3.1	3.4	1.7	1.8
Wheeze or whistling in the chest in last year	2.2	3.9	4.8	-1.7	-2.2
Relative age of first facial hair	2.1	4.3	5.4	-2.3	-1.8
Medication: Atenolol	2.1	2.6	3.5	1.3	1.9
Forced expiratory volume in 1-second (FEV1)	2.1	7.0	8.5	2.9	2.4
Ever depressed for a whole week	2.1	2.6	3.2	1.8	1.4
Systolic Blood Pressure	2.0	10.1	10.6	-3.2	-3.1
Hearing difficulty/problems: Yes	2.0	3.0	4.7	2.2	1.2
Frequency of tenseness / restlessness in last 2 weeks	2.0	3.1	3.2	-1.7	-1.8
Medication for cholesterol, blood pressure or diabetes	2.0	3.2	4.0	1.6	2.0
Heel T-Score	1.9	15.0	16.4	-4.0	-3.7
Eye problems/disorders: None of the above	1.8	2.1	2.2	1.5	1.4
Illnesses of father: None of the above (group 1)	1.8	2.2	2.9	1.2	1.7
Weight	1.7	8.5	10.8	3.3	2.5
Forced expiratory volume in 1-second (FEV1), Best measure	1.7	5.4	5.5	2.4	2.3
Friendships satisfaction	1.7	2.2	3.9	0.7	2.0
Blood Red Count	1.6	15.3	17.2	3.7	4.1
Pain all over the body in last month	1.6	1.7	1.9	-1.4	-1.2
Tense / ‘highly strung’	1.6	2.6	3.4	1.8	1.4
Glaucoma (self-reported)	1.6	1.9	2.8	-1.0	-1.7
Average weekly champagne plus white wine intake	1.6	2.2	3.5	1.0	1.9
Age started oral contraceptive pill	1.6	2.0	3.3	0.8	1.8
Alzheimer’s Disease (in mother)	1.5	1.7	2.2	1.1	1.5
Fasting Glucose	1.5	1.8	2.1	-1.4	-1.2
Hip circumference	1.5	6.4	7.8	2.8	2.2
Happiness	1.5	1.9	3.0	0.9	1.7
Medication: Paracetamol	1.5	2.5	3.2	1.8	1.4
Number of full brothers	1.5	1.9	1.9	-1.4	-1.4
Heart disease (mother)	1.5	1.9	2.4	1.6	1.2
Chronic bronchitis/emphysema (father)	1.4	1.7	1.8	1.3	1.2
Medication: Simvastatin	1.4	2.0	3.0	-1.0	-1.7
Suffer from ‘nerves’	1.4	2.2	2.3	1.5	1.5
Overall health rating	1.4	3.1	3.4	-1.8	-1.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.4	1.7	1.7	1.3	1.3
Irritability	1.4	2.4	2.8	-1.7	-1.5
Commuting to job workplace: Cycle	1.4	1.7	2.0	1.1	1.4
Crohns Disease (2012)	1.3	2.0	2.7	-1.2	-1.6
Length of working week for main job	1.3	1.4	1.8	1.0	1.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.3	1.5	2.1	-1.4	-1.0
Ovarian Cancer	1.2	1.6	1.7	-1.3	-1.3
Ever used hormone-replacement therapy (HRT)	1.2	1.5	2.4	0.8	1.6
Systolic blood pressure, automated reading	1.2	3.6	4.3	-2.1	-1.7
Medication: Metformin	1.2	1.7	2.6	-0.9	-1.6
Leg fat-free mass (left)	1.2	6.4	8.1	2.9	2.2
Headache pain in last month	1.2	2.1	2.2	1.5	1.4
Medication: Ventolin 100micrograms inhaler	1.2	1.6	2.6	-0.7	-1.6
Leg fat-free mass (right)	1.2	6.5	8.5	2.9	2.1
Diabetes diagnosed by doctor	1.2	2.0	2.9	-1.0	-1.7
Leg predicted mass (right)	1.2	6.4	8.4	2.9	2.1
Hand grip strength (right)	1.1	3.0	3.1	1.8	1.7
Leg predicted mass (left)	1.1	6.0	7.7	2.8	2.1
Medication: Ibuprofen (e.g. Nurofen)	1.1	1.4	1.7	1.3	1.1
Breastfed as a baby	1.1	1.4	2.5	1.6	0.5
Medication for pain relief, constipation, heartburn	1.1	1.9	3.0	-1.7	-0.9
Medication: Seretide 50 evohaler	1.1	1.2	1.2	-1.1	-1.1
Medication: Paracetamol	1.1	1.8	2.4	1.5	1.1
Worry (Nagel 2018)	1.0	2.2	2.3	1.5	1.5
Body Mass Index (BMI) (2010)	1.0	1.3	1.4	-1.2	-1.1
Neuroticism	1.0	2.4	3.5	1.1	1.9
Hand grip strength (left)	1.0	2.6	3.1	1.8	1.4
Townsend deprivation index at recruitment	1.0	1.4	1.7	-1.3	-1.1
Nervous feelings	1.0	1.8	2.0	1.3	1.4
Ever unenthusiastic/disinterested for a whole week	1.0	1.3	1.5	1.2	1.0
Noisy workplace	1.0	1.3	1.4	-1.2	-1.1
Prospective memory result	1.0	1.2	1.4	1.1	1.2
Pulse wave Arterial Stiffness index	1.0	1.1	1.2	1.1	1.0
Peak expiratory flow (PEF)	1.0	2.3	2.7	1.6	1.4
Long-standing illness, disability or infirmity	1.0	1.6	1.6	-1.2	-1.3
Risk taking	1.0	1.5	2.0	-1.4	-1.0
Alcohol drinker status: Previous	1.0	1.1	1.5	0.9	1.2
Pack years of smoking	1.0	1.4	1.7	1.3	1.1
Cardiovascular Disease	0.9	3.0	4.3	-1.3	-2.1
Qualifications: CSEs or equivalent	0.9	1.1	1.3	-1.0	-1.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.9	1.2	1.6	0.9	1.3
Miserableness	0.9	1.6	2.1	1.1	1.5
Verbal and Numeric Reasoning (VNR)	0.8	1.8	1.9	1.3	1.4
Taking other prescription medications	0.8	1.2	2.3	-0.4	-1.5
Stomach or abdominal pain in last month	0.8	0.9	1.3	-1.1	-0.8
Medication: Ramipril	0.8	1.1	1.6	0.7	1.3
Comparative body size at age 10	0.8	2.3	3.5	1.9	1.1
Reason for reducing amount of alcohol drunk: Health precaution	0.8	0.9	1.0	1.0	0.9
Pulse wave peak to peak time	0.8	0.9	0.9	-0.9	-0.9
Qualifications: College or University degree	0.8	2.4	3.3	1.2	1.8
Cholesterol lowering medication	0.8	1.2	1.4	-1.0	-1.2
Average weekly spirits intake	0.7	0.8	1.2	1.1	0.7
Family relationship satisfaction	0.7	0.9	1.7	-0.0	1.3
Pain type(s) experienced in last month: Hip pain	0.7	0.9	1.6	0.6	1.2
Medication: Lisinopril	0.7	0.9	1.6	-0.6	-1.2
Medication: Atorvastatin	0.7	0.9	0.9	-1.0	-1.0
Blood Eosinophil Count	0.6	4.6	4.7	2.2	2.1
Bilateral oophorectomy (both ovaries removed)	0.6	0.7	1.3	0.4	1.1
Diabetes (self-reported)	0.6	0.9	1.4	-0.5	-1.2
Qualifications: A levels/AS levels or equivalent	0.6	1.4	2.3	0.7	1.5
Mouth/teeth dental problems: Dentures	0.6	1.0	1.8	-0.4	-1.3
Medication: Lansoprazole	0.6	0.7	0.7	-0.8	-0.8
Loneliness, isolation	0.6	0.9	0.9	0.9	0.9
Qualifications: nursing, teaching	0.6	1.0	1.3	0.8	1.1
Number of self-reported non-cancer illnesses	0.6	1.0	1.3	-0.8	-1.1
Major Depression (MDD)	0.5	0.6	1.3	0.1	1.1
Primary Biliary Cirrhosis	0.5	0.7	1.3	-0.4	-1.1
Supplements: Zinc	0.5	0.6	1.0	-0.4	-1.0
Trunk fat mass	0.5	2.1	3.1	1.8	1.0
Hearing difficulty/problems with background noise	0.5	0.8	1.1	1.1	0.7
Falls in the last year	0.5	0.7	1.0	-0.7	-1.0
Ever highly irritable/argumentative for 2 days	0.5	0.6	0.6	-0.8	-0.7
Neck or shoulder pain in last month	0.5	0.7	0.7	0.8	0.9
Had major operations	0.5	0.5	1.1	1.0	0.1
Knee pain experienced in last month	0.5	0.7	1.1	-0.6	-1.0
Osteoarthritis (self-reported)	0.5	0.7	0.9	-0.9	-0.7
Diastolic blood pressure, automated reading	0.5	1.5	2.0	-1.0	-1.4
Unable to work because of sickness or disability	0.5	0.6	0.9	1.0	0.6
Myopia	0.5	0.8	1.3	-0.5	-1.1
Depression (Nagel 2018)	0.4	0.6	1.1	1.0	0.3
Schizophrenia vs Biploar Disorder	0.4	0.5	1.0	-1.0	-0.3
Neuroticism (2016)	0.4	0.5	1.0	0.2	1.0
Triglycerides	0.4	0.6	0.8	-0.9	-0.7
Hypothyroidism (self reported)	0.4	0.8	1.0	-0.8	-1.0
Lung FVC	0.4	2.1	2.6	1.3	1.6
Vitamin and mineral supplements	0.4	0.6	1.0	0.4	1.0
Pack years adult smoking proportion	0.4	0.6	0.9	1.0	0.5
Fed-up feelings	0.4	0.8	1.4	-1.2	-0.5
Alcohol intake versus 10 years previously	0.4	0.5	1.0	-0.2	-1.0
Hair/balding pattern: Pattern 3	0.4	0.7	0.9	0.9	0.7
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	0.6	-0.8	-0.6
Medication: Amlodipine	0.4	0.6	1.2	-0.2	-1.1
Exposure to tobacco smoke outside home	0.4	0.5	0.8	0.9	0.4
Shortness of breath walking on level ground	0.4	0.5	0.5	0.6	0.7
Angina (self-reported)	0.4	0.5	0.7	-0.5	-0.9
Wears glasses or contact lenses	0.4	0.4	0.5	0.6	-0.7
Ever taken oral contraceptive pill	0.4	0.5	0.6	0.8	0.6
Financial situation satisfaction	0.4	0.4	0.5	0.6	0.7
Fractured/broken bones in last 5 years	0.4	0.5	0.9	-0.4	-1.0
HbA1C	0.3	0.3	0.4	-0.6	-0.6
Lupus	0.3	0.4	0.5	0.7	0.6
Type 2 Diabetes (T2D) (2018)	0.3	0.6	0.9	-0.6	-0.9
Lung FEV1/FVC ratio	0.3	1.3	2.2	-0.6	-1.5
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	0.4	0.6	0.6
Angina	0.3	0.4	0.5	-0.5	-0.7
Medication for hormone replacement therapy	0.3	0.3	0.7	-0.8	0.1
Average weekly fortified wine intake	0.3	0.3	0.6	-0.1	0.8
Maternal smoking around birth	0.3	0.4	0.5	0.7	-0.4
High blood pressure	0.3	0.8	1.3	1.1	0.5
Supplements: Glucosamine	0.3	0.3	0.7	-0.8	-0.2
High blood pressure (mother)	0.3	0.4	0.5	-0.5	-0.7
Hair/balding pattern: Pattern 2	0.3	0.4	0.7	-0.9	-0.1
Financial difficulties in last 2 years	0.3	0.4	0.7	-0.3	-0.8
Fluid intelligence score	0.3	0.6	0.6	0.8	0.8
Neuroticism score	0.3	0.6	1.1	0.4	1.0
Impedance of arm (left)	0.3	1.3	1.7	-1.3	-1.0
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.5	0.6	0.6	0.8
Emphysema/chronic bronchitis	0.3	0.3	0.4	0.6	0.4
Whole body fat mass	0.3	1.1	1.8	1.3	0.6
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	0.7	0.3	0.8
Supplements: Vitamin C	0.3	0.3	0.5	0.7	0.4
Hypertension (Self-reported)	0.3	0.8	1.2	1.1	0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.3	0.6	-0.3	-0.8
Commuting to job workplace: Walk	0.3	0.3	0.6	-0.8	-0.1
Mouth/teeth dental problems: Mouth ulcers	0.3	0.4	0.5	-0.7	-0.6
Mother’s age at death	0.3	0.4	0.6	-0.8	-0.5
Tinnitus: Yes, now most or all of the time	0.3	0.4	0.8	-0.2	-0.9
Vascular/heart problems diagnosed by doctor	0.3	0.9	1.6	-1.3	-0.4
Pain experienced in last month	0.3	0.4	0.7	0.8	0.5
Bipolar Disorder (2018)	0.2	0.3	0.4	-0.5	0.6
Age at First Birth	0.2	0.2	0.5	0.7	0.1
Hair Pigment	0.2	5.9	6.8	2.6	2.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.3	0.6	0.8	-0.2
Age when periods started (menarche)	0.2	0.5	0.8	-0.9	-0.5
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	0.2	-0.3	-0.5
Illnesses of siblings	0.2	0.2	0.4	0.6	0.2
Hair/balding pattern: Pattern 4	0.2	0.4	0.6	0.8	0.4
Blood clot in the leg (DVT)	0.2	0.2	0.4	-0.6	0.1
Migraine (self-reported)	0.2	0.2	0.3	0.6	0.3
Medication: Ibuprofen	0.2	0.3	0.4	0.6	0.4
Medication: Allopurinol	0.2	0.2	0.3	-0.4	-0.5
Commuting to job workplace: Car/motor vehicle	0.2	0.2	0.4	0.2	0.6
Medication: Aspirin	0.2	0.3	0.3	0.5	-0.5
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.4	0.5	0.7	0.5
Arm fat percentage (left)	0.2	0.9	1.5	-0.5	-1.2
Mood swings	0.2	0.4	0.6	-0.5	-0.7
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	0.2	-0.5	-0.3
Back pain experienced in last month	0.2	0.3	0.5	-0.7	-0.2
Mineral and other dietary supplements	0.2	0.3	0.4	-0.5	-0.6
Smoking status: Current	0.2	0.3	0.5	-0.5	-0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.4	0.6	0.5	0.8
Arm fat mass (left)	0.2	0.7	1.4	1.2	0.4
Commuting to job workplace: Public transport	0.2	0.2	0.3	-0.6	-0.3
Supplements: Fish oil (including cod liver oil)	0.2	0.2	0.3	0.6	0.3
Medication: Bendroflumethiazide	0.2	0.3	0.6	0.8	-0.0
Alcohol drinker status: Never	0.2	0.2	0.3	-0.4	-0.6
Leg fat mass (left)	0.2	0.7	1.3	1.1	0.5
Bipolar Disorder or Schizophrenia	0.1	0.2	0.3	-0.6	0.2
Intelligence (Savage-Jansen 2018)	0.1	0.3	0.5	0.7	0.2
Neuroticism (Nagel 2018)	0.1	0.3	0.3	0.5	0.6
Alzheimer’s Disease (in father)	0.1	0.1	0.2	0.4	0.0
Reaction Time	0.1	0.1	0.2	0.2	-0.5
Prostate Cancer	0.1	0.1	0.2	0.1	0.4
Coronary Artery Disease (CAD)	0.1	0.1	0.2	0.2	-0.5
Mean Putamen Volume	0.1	0.1	0.1	-0.3	-0.3
Smoking Status	0.1	0.2	0.2	0.5	0.3
Number of treatments/medications taken	0.1	0.1	0.3	0.1	-0.5
Sensitivity / hurt feelings	0.1	0.1	0.2	0.2	0.4
Medication: Co-codamol	0.1	0.1	0.2	-0.3	-0.4
Severe depression (siblings)	0.1	0.1	0.2	0.3	-0.5
Impedance of leg (right)	0.1	0.7	1.1	0.5	1.1
Current tobacco smoking	0.1	0.2	0.3	-0.3	-0.5
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.3	0.4	-0.6	-0.5
Serious illness, injury or assault to yourself	0.1	0.2	0.3	-0.3	-0.5
Multivitamins +/- minerals	0.1	0.1	0.2	-0.2	-0.4
Medication: Levothyroxine sodium	0.1	0.1	0.2	0.5	0.2
Body mass index (BMI)	0.1	0.2	0.4	0.1	-0.7
Impedance of leg (left)	0.1	0.5	0.8	0.5	0.9
Number of incorrect matches in round	0.1	0.2	0.2	-0.5	-0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.2	0.3	-0.5	-0.3
Impedance of arm (right)	0.1	0.6	1.0	-1.0	-0.5
Arm fat percentage (right)	0.1	0.5	0.8	-0.3	-0.9
Father’s age at death	0.1	0.1	0.1	-0.4	0.1
Number of live births	0.1	0.1	0.3	-0.5	-0.1
Illnesses of mother	0.1	0.2	0.3	-0.3	-0.5
Arm fat mass (right)	0.1	0.6	1.1	1.1	0.2
Loud music exposure frequency	0.1	0.1	0.1	-0.2	-0.3
Worry too long after embarrassment	0.1	0.2	0.4	0.3	0.6
Number of children fathered	0.1	0.1	0.1	-0.3	-0.1
Age at first live birth	0.1	0.2	0.3	0.5	0.5
Medication: Blood pressure	0.1	0.2	0.3	0.6	-0.2
Medication: Omeprazole	0.1	0.1	0.1	0.3	-0.4
Mean time to correctly identify matches	0.1	0.3	0.3	0.5	0.6
Leg fat mass (right)	0.1	0.6	1.0	1.0	0.4
Pulse rate, automated reading	0.1	0.2	0.3	0.6	0.0
Alcohol intake frequency.	0.1	0.1	0.3	0.5	-0.1
Chest pain or discomfort	0.1	0.2	0.2	-0.4	-0.4
Illnesses of father: Heart disease	0.1	0.1	0.2	-0.1	-0.4
Medication: Aspirin	0.1	0.2	0.3	0.5	-0.3
Medication: Gliclazide	0.1	0.1	0.3	0.5	0.2
Medication: Blood pressure	0.1	0.3	0.3	0.6	0.4
Ever smoked	0.1	0.1	0.2	0.1	-0.5
Medication: Omeprazole (e.g. Zanprol)	0.1	0.1	0.1	0.3	-0.3
Deep venous thrombosis (DVT) (self-reported)	0.1	0.1	0.3	-0.5	0.0
Depressed Affect (Nagel 2018)	0.0	0.1	0.1	-0.3	-0.2
Schizophrenia (2018)	0.0	0.1	0.1	-0.4	-0.2
Bipolar Disorder (2011)	0.0	0.0	0.0	-0.1	0.0
HDL Cholesterol	0.0	0.0	0.0	0.1	0.1
Rheumatoid Arthritis	0.0	0.0	0.1	-0.3	-0.1
Schizophrenia (2014)	0.0	0.0	0.0	-0.2	0.2
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.0	-0.2	0.1
BMI	0.0	0.1	0.1	0.3	0.1
Chronotype (morning person)	0.0	0.0	0.0	-0.2	0.0
Tanning	0.0	0.5	0.9	-0.2	1.0
Frequency of depressed mood in last 2 weeks	0.0	0.0	0.0	-0.1	-0.2
Ever had hysterectomy (womb removed)	0.0	0.0	0.1	-0.0	0.2
Diabetes (mother)	0.0	0.0	0.0	0.1	-0.1
Trunk fat percentage	0.0	0.1	0.3	0.5	-0.1
Diverticular disease/diverticulitis (self-reported)	0.0	0.0	0.1	0.2	0.2
Waist circumference	0.0	0.0	0.1	0.3	-0.1
Past tobacco smoking	0.0	0.0	0.0	-0.0	0.1
Qualifications: None of the above	0.0	0.1	0.1	-0.4	-0.2
Worrier / anxious feelings	0.0	0.0	0.0	0.2	0.1
Frequency of tiredness / lethargy in last 2 weeks	0.0	0.0	0.1	0.1	-0.2
Pulse rate	0.0	0.0	0.0	-0.2	0.2
Serious illness, injury or assault of a close relative in last 2 years	0.0	0.0	0.1	0.3	0.0
Depression (self-reported)	0.0	0.0	0.0	0.0	-0.1
Exposure to tobacco smoke at home	0.0	0.0	0.0	0.1	0.1
Qualifications: O levels/GCSEs or equivalent	0.0	0.0	0.0	-0.1	0.1
Hypothyroidism/myxoedema (self-reported)	0.0	0.0	0.0	-0.1	-0.2
High blood pressure (siblings)	0.0	0.0	0.0	-0.1	0.1
Body fat percentage	0.0	0.1	0.2	0.2	-0.4
Leg fat percentage (right)	0.0	0.0	0.0	0.0	-0.2
Health satisfaction	0.0	0.0	0.0	-0.0	0.2
Mouth/teeth dental problems: Loose teeth	0.0	0.0	0.1	0.2	-0.2
Number of full sisters	0.0	0.0	0.0	-0.2	-0.0
Age at last live birth	0.0	0.0	0.1	-0.2	-0.2
Leg pain on walking	0.0	0.0	0.0	0.0	-0.1
Smoking status: Previous	0.0	0.0	0.0	-0.2	-0.1
Ever had bowel cancer screening	0.0	0.1	0.1	0.3	-0.1
Eye problems/disorders: Cataract	0.0	0.0	0.0	-0.0	-0.1
Medication for cholesterol	0.0	0.0	0.1	0.3	-0.0
Guilty feelings	0.0	0.0	0.0	-0.0	0.2
Leg fat percentage (left)	0.0	0.0	0.1	0.3	-0.1
Average weekly beer plus cider intake	0.0	0.1	0.1	0.4	-0.1
Supplements: Calcium	0.0	0.0	0.0	0.1	0.2
Basal cell carcinoma (self-reported)	0.0	0.1	0.1	0.2	0.2
Heart disease (siblings)	0.0	0.0	0.0	-0.2	0.2
Impedance of whole body	0.0	0.1	0.3	-0.5	-0.1

Hub : Genes

CXCR1

Models

Trait associations