Hub : Genes

CYHR1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Esophagus Mucosa 0.0460 0.0240 5.3e-03 0.017 NA 0.019 NA 0.012 2.3e-02 NA 1.9e-02 NA 4.9e-02
2 GTEx Nerve Tibial 0.0611 0.0282 2.6e-03 0.060 NA 0.021 NA -0.003 4.6e-05 NA 1.2e-02 NA 6.1e-01
3 GTEx Skin Sun Exposed Lower leg 0.0800 0.0360 1.6e-03 0.014 NA 0.040 NA 0.022 2.2e-02 NA 3.0e-04 NA 5.5e-03
4 GTEx Spleen 0.1340 0.0700 8.3e-03 0.003 NA -0.012 NA -0.011 2.6e-01 NA 9.7e-01 NA 8.5e-01
5 GTEx Thyroid 0.0760 0.0300 3.8e-04 0.096 NA 0.042 NA 0.004 8.7e-08 NA 3.5e-04 NA 1.5e-01
6 ROSMAP Brain Pre-frontal Cortex 0.0859 0.0279 1.7e-10 0.082 0.072 0.101 0.06 0.040 9.2e-11 1.5e-09 5.9e-13 3.5e-08 5.4e-06
7 TCGA Breast Invasive Carcinoma 0.0425 0.0236 8.0e-06 0.027 0.030 0.028 NA 0.027 2.1e-06 6.8e-07 1.8e-06 NA 2.9e-06
8 TCGA Prostate Adenocarcinoma 0.0319 0.0212 3.6e-03 0.009 0.008 0.010 NA 0.012 3.3e-02 4.5e-02 2.8e-02 NA 1.7e-02

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.6 1.0 6.0 1.1 -0.6 0.0 2.4 0.1 -0.5 -0.0 0.0
Bipolar Disorder or Schizophrenia 0.5 1.2 4.3 1.6 -0.3 1.4 2.1 0.4 0.3 -0.8 0.0
Depressed Affect (Nagel 2018) 0.3 0.7 1.3 -0.6 -0.9 -0.3 0.4 -1.1 -1.1 -0.5 1.0
Depression (Nagel 2018) 0.6 0.9 5.2 -0.1 0.8 0.5 -0.3 0.3 0.6 -2.3 -0.6
Intelligence (Savage-Jansen 2018) 8.2 25.1 40.2 -0.4 -5.3 -6.3 4.2 -5.5 -5.5 4.5 5.7
Neuroticism (Nagel 2018) 0.3 0.7 1.6 -0.8 1.1 0.7 -0.7 0.8 0.4 -1.2 -1.0
Schizophrenia (2018) 0.4 0.8 3.1 1.1 0.1 1.8 0.7 0.5 0.6 -1.1 0.0
Schizophrenia vs Biploar Disorder 1.7 2.2 3.8 1.2 1.8 2.0 -1.6 1.6 1.6 -1.1 0.0
Worry (Nagel 2018) 0.1 0.3 1.0 -1.0 0.3 0.4 0.0 0.2 -0.2 -0.7 -0.6
Alzheimer’s Disease (in mother) 1.3 1.6 3.2 -0.9 -1.4 -0.3 -0.4 -1.5 -1.8 1.6 1.1
Alzheimer’s Disease (in father) 0.4 0.4 1.7 0.7 -0.0 0.9 1.3 0.3 -0.1 0.1 -0.3
Alzheimer’s Disease (including proxy) 0.2 0.3 0.7 -0.0 -0.6 0.7 -0.1 -0.5 -0.8 0.7 0.1
Crohns Disease (2017) 0.4 0.9 2.4 -1.5 -1.0 0.1 0.6 -0.8 -1.2 1.1 0.8
Irritable Bowel Disease (IBD) 1.1 2.6 3.6 -1.9 -1.8 -1.2 1.5 -1.3 -1.8 1.6 1.7
Ulcerative Colitis (UC) 1.2 2.3 2.9 -1.4 -1.7 -1.7 1.6 -1.2 -1.6 1.1 1.7
Major Depression (MDD) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0
Reaction Time 6.5 12.4 22.5 1.6 4.5 1.8 -0.9 4.3 4.4 -3.4 -4.7
Verbal and Numeric Reasoning (VNR) 6.8 16.4 26.1 1.1 -4.6 -4.5 3.9 -4.6 -4.3 2.9 5.1
Breast Cancer 0.7 1.8 4.0 0.4 -1.9 -0.5 0.7 -1.9 -1.2 1.0 2.0
Ovarian Cancer 0.9 1.1 2.8 0.9 -1.7 0.4 0.8 -1.4 -0.9 -0.3 1.3
Prostate Cancer 2.3 3.2 5.4 0.5 2.1 1.2 -1.7 1.8 2.1 -1.7 -2.3
Age at First Birth 9.6 14.0 22.9 -0.4 -4.0 -3.9 3.5 -4.5 -4.1 2.9 4.8
Bipolar Disorder (2011) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Body Mass Index (BMI) (2010) 0.1 0.1 0.5 -0.2 -0.0 -0.7 -0.4 -0.1 -0.1 -0.4 -0.1
Coronary Artery Disease (CAD) 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.6 -0.0 0.0
Crohns Disease (2012) 1.1 1.7 4.0 -2.0 -1.4 -0.9 1.3 -1.2 -1.5 1.3 0.0
Mean Putamen Volume 1.2 1.3 4.8 -0.9 -1.2 -2.2 0.4 -1.1 -0.9 1.2 0.0
Fasting Glucose 0.6 0.7 1.5 -0.8 -0.5 -1.0 0.0 -0.7 -0.9 1.2 0.7
HbA1C 0.6 0.7 1.3 -0.5 -0.9 -0.4 -1.1 -0.8 -0.5 1.1 1.0
HDL Cholesterol 0.3 0.5 1.7 1.3 -0.1 0.2 1.3 0.3 0.5 -0.4 -0.3
LDL Cholesterol 0.2 0.3 0.9 -0.9 0.5 -0.6 0.7 0.3 0.3 -0.4 -0.3
Lupus 0.1 0.2 0.8 0.3 -0.1 -0.8 -0.9 0.1 0.1 0.2 0.0
Neuroticism (2016) 0.5 0.7 1.6 0.3 1.2 0.6 0.2 1.1 0.7 -0.6 -1.2
Primary Biliary Cirrhosis 0.2 0.3 1.1 -1.0 0.5 -0.5 -0.3 0.3 0.2 0.5 -0.4
Rheumatoid Arthritis 1.2 1.6 3.4 -0.0 1.7 0.8 -1.1 1.5 1.8 -1.6 0.0
Schizophrenia (2014) 1.3 2.8 9.6 1.3 0.9 3.1 1.3 1.2 1.4 -2.4 0.0
Triglycerides 0.4 0.7 2.3 -1.5 0.4 0.8 -1.4 0.1 -0.1 -0.6 -0.4
Type 2 Diabetes (T2D) (2012) 0.5 0.5 4.4 0.0 0.0 0.0 0.0 0.0 -2.1 0.0 0.0
Ulcerative Colitis 1.8 2.6 5.3 -0.7 -2.0 -1.4 2.3 -1.7 -2.1 1.2 0.0
Blood Eosinophil Count 0.1 0.8 3.7 -0.1 0.1 -1.4 1.9 0.2 -0.1 0.6 -0.2
Blood Platelet Count 0.5 5.4 10.2 1.2 2.8 2.0 0.3 3.2 2.3 -2.5 -2.9
Blood Red Count 0.9 9.0 16.5 -0.2 -3.6 -1.6 2.7 -3.9 -2.7 3.2 4.1
Blood White Count 0.1 0.6 1.9 -1.4 -0.2 -0.3 0.6 -0.4 -1.0 1.1 0.5
Heel T-Score 0.1 1.0 3.5 -1.2 -0.3 -1.6 -0.4 -0.1 0.4 1.9 -0.6
BMI 0.1 0.3 1.1 0.2 0.3 1.1 -0.5 0.3 0.5 -0.7 0.3
Height 0.1 2.7 7.2 -0.9 -2.2 1.2 0.1 -2.7 -1.0 1.2 2.2
Waist Hip Ratio (WHR) 0.1 0.6 3.0 -1.7 -0.7 0.2 0.1 -0.7 -0.7 0.4 0.5
Systolic Blood Pressure 1.1 5.7 12.5 -3.3 -1.5 -1.0 -2.6 -1.5 -2.2 3.5 2.1
Smoking Status 4.4 10.4 17.6 2.0 3.7 3.2 0.0 3.7 3.2 -3.7 -4.2
Allergy or Eczema 0.7 1.8 3.2 0.2 -1.4 -1.6 1.2 -1.7 -1.8 0.8 1.3
Cardiovascular Disease 3.2 10.7 17.5 -3.8 -3.2 -2.5 -0.5 -3.1 -4.2 3.9 3.4
Hypothyroidism (self reported) 0.4 0.9 1.6 1.3 1.1 0.6 0.7 1.1 0.9 -0.8 -1.1
Respiratory disease 0.7 1.7 3.8 -0.1 1.8 0.6 -0.8 1.4 1.6 -0.9 -2.0
Type 2 Diabetes (T2D) (2018) 8.5 15.9 25.0 -5.0 -4.3 -3.1 -0.7 -4.4 -4.2 4.2 4.3
Lung FEV1/FVC ratio 0.3 1.6 8.6 1.5 -0.5 -1.2 2.9 -0.1 -0.1 0.2 0.5
Lung FVC 4.5 22.9 36.9 3.0 6.1 4.1 -2.5 5.6 5.2 -5.1 -5.4
Neuroticism 0.1 0.3 1.7 -1.3 0.6 0.0 -0.2 0.3 -0.2 -0.1 -0.5
Chronotype (morning person) 0.0 0.1 0.3 0.3 0.1 0.0 0.5 0.2 -0.2 -0.5 -0.3
Hair Pigment 0.1 2.3 5.4 1.7 1.2 2.3 0.0 1.8 1.2 -0.5 -2.0
Tanning 0.1 1.5 4.8 -0.2 1.0 2.2 -1.7 0.9 1.4 0.1 -0.5
Hand grip strength (left) 1.0 2.7 4.8 2.2 1.6 1.6 -0.2 1.6 1.3 -2.1 -1.8
Number of treatments/medications taken 0.4 0.8 2.9 -1.3 -0.3 -1.7 0.1 0.0 -0.4 1.1 0.5
Average weekly spirits intake 6.4 7.9 16.7 0.1 3.4 2.3 -1.8 3.2 3.2 -2.5 -4.1
Sensitivity / hurt feelings 2.3 4.0 7.7 1.2 2.8 -0.6 -1.2 2.4 2.5 -1.5 -2.6
Frequency of depressed mood in last 2 weeks 0.6 0.9 3.9 0.2 0.6 0.1 -1.1 0.3 0.8 -2.0 -0.9
Hearing difficulty/problems: Yes 2.5 3.8 6.8 1.3 2.6 1.8 -1.1 2.6 2.3 -0.9 -2.2
Relative age of first facial hair 0.9 1.9 8.5 -2.9 -0.6 -1.9 -0.2 -0.8 -1.0 0.6 0.7
Other serious medical condition/disability diagnosed by doctor 0.1 0.1 0.2 -0.2 -0.4 -0.4 -0.1 -0.5 -0.2 -0.3 0.4
Ever used hormone-replacement therapy (HRT) 0.5 0.7 2.5 -0.5 0.6 -1.6 -1.0 0.7 0.3 0.6 -0.4
Ever had hysterectomy (womb removed) 1.0 1.2 2.4 -1.5 1.1 -1.6 -1.3 0.8 0.5 0.1 -0.8
Systolic blood pressure, automated reading 0.5 1.5 4.8 -2.2 -0.1 0.5 -2.0 0.0 -0.3 1.6 0.8
Eye problems/disorders: Diabetes related eye disease 3.6 4.0 6.7 -2.3 -2.4 -1.2 -0.0 -2.1 -2.1 2.0 2.6
Angina 0.3 0.4 1.7 -0.1 -0.7 -0.3 0.8 -0.5 -1.3 0.2 0.6
Medication for hormone replacement therapy 0.7 0.7 2.8 -1.1 0.2 -1.0 -1.7 0.0 -0.4 0.8 -0.3
Vitamin and mineral supplements 1.7 2.4 4.3 1.5 1.8 0.5 -0.6 1.6 1.7 -1.9 -2.1
Supplements: Zinc 0.5 0.5 1.0 -1.0 0.7 -0.0 -0.8 0.5 0.5 -1.0 -0.8
Medication: Co-codamol 1.1 1.3 4.3 0.4 0.9 2.1 0.5 0.8 0.8 -1.6 -0.9
Medication: Metformin 3.7 5.3 12.1 -3.5 -2.1 -1.6 -1.6 -2.2 -2.4 1.9 2.5
Diabetes (father) 1.1 1.4 1.8 -1.2 -1.4 -1.1 -0.3 -1.2 -1.2 1.2 1.3
Diabetes (mother) 0.2 0.2 0.6 0.8 0.4 0.4 -0.0 0.5 0.2 -0.4 -0.6
Severe depression (siblings) 3.0 3.4 5.7 2.4 2.2 1.0 -0.7 2.1 2.0 -1.3 -2.3
Pack years adult smoking proportion 1.1 1.6 2.7 1.6 -1.3 -1.4 1.5 -1.6 -0.7 0.5 1.2
Impedance of leg (right) 0.1 0.4 1.8 -0.6 0.3 0.0 -0.1 0.4 0.9 -0.2 -1.4
Leg fat-free mass (left) 0.1 0.7 3.2 0.4 0.5 1.8 -0.6 0.2 0.6 -1.0 0.1
Trunk fat percentage 0.0 0.2 0.4 -0.6 0.2 0.5 0.6 0.2 0.5 0.2 0.1
Hand grip strength (right) 0.3 0.9 4.9 2.2 0.1 0.0 0.3 -0.1 -0.2 -1.4 -0.3
Townsend deprivation index at recruitment 0.0 0.1 0.3 -0.2 0.0 0.3 0.1 0.0 0.0 -0.6 -0.2
Current tobacco smoking 0.6 0.9 1.4 1.2 1.2 0.4 0.9 1.1 0.8 -0.7 -1.2
Average weekly fortified wine intake 1.1 1.3 3.0 -1.0 -0.7 -1.2 -0.6 -1.4 -1.6 0.1 1.7
Maternal smoking around birth 1.7 2.5 9.1 0.1 1.5 1.1 -1.3 1.2 1.2 -3.0 -1.7
Fed-up feelings 0.6 1.1 3.0 -0.6 0.6 1.7 -1.5 0.6 0.6 -1.2 -0.7
Frequency of unenthusiasm / disinterest in last 2 weeks 2.6 3.5 9.9 0.4 1.8 2.0 -1.2 1.4 1.7 -3.1 -2.0
Relative age voice broke 0.4 0.6 1.7 -1.3 0.7 -0.8 0.1 0.7 0.5 -0.5 -0.9
Taking other prescription medications 0.3 0.5 1.7 -1.3 0.2 -0.8 -0.8 0.3 -0.0 0.9 -0.0
Age when periods started (menarche) 0.5 1.3 3.5 -1.9 -1.0 -0.3 -0.0 -1.2 -1.1 1.2 1.2
Bilateral oophorectomy (both ovaries removed) 1.9 2.2 4.1 -2.0 1.1 -1.8 -1.9 0.9 0.5 2.0 -0.5
Heel bone mineral density (BMD) T-score, automated (left) 0.4 0.8 5.1 -2.3 0.4 0.1 -0.6 0.4 0.6 0.3 -0.4
Tinnitus: Yes, but not now, but have in the past 0.5 0.6 2.7 0.8 0.5 -0.1 1.6 0.4 0.7 0.1 -0.2
Qualifications: CSEs or equivalent 4.2 5.5 10.6 -0.1 2.4 2.3 -1.8 2.2 2.3 -3.1 -3.3
Serious illness, injury or assault to yourself 0.7 0.9 1.7 0.2 1.0 0.8 -0.6 1.2 1.0 -1.0 -1.3
High blood pressure 1.3 3.8 11.9 -3.4 -1.2 -0.7 -1.5 -1.2 -2.0 2.2 2.0
Hayfever, allergic rhinitis or eczema 1.6 3.6 5.8 0.2 -2.0 -2.1 1.7 -2.2 -2.4 0.8 2.4
Multivitamins +/- minerals 3.0 3.8 8.0 -1.4 -2.3 -0.8 1.3 -2.0 -2.0 2.3 2.8
Stomach or abdominal pain in last month 1.0 1.3 2.6 -1.2 1.2 -0.3 -0.2 1.3 0.9 -1.5 -1.6
Supplements: Glucosamine 3.4 4.4 6.7 -1.5 -2.1 -2.5 1.1 -2.2 -2.0 2.4 2.6
Diverticular disease/diverticulitis (self-reported) 0.7 0.8 1.9 -0.1 -1.0 -1.4 1.2 -0.7 -0.1 1.1 0.8
Medication: Atenolol 0.4 0.5 1.8 -1.2 0.6 -0.7 -1.4 0.4 -0.1 -0.0 0.0
Medication: Levothyroxine sodium 0.1 0.1 0.5 0.7 0.2 0.1 0.6 0.3 0.2 0.1 -0.1
Sitting height 0.0 0.3 0.7 -0.8 -0.0 0.7 -0.2 -0.6 0.5 -0.3 0.5
Chronic bronchitis/emphysema (father) 0.6 0.7 1.4 -1.1 -0.8 -1.2 -0.1 -1.1 -0.9 0.3 0.5
High blood pressure (mother) 0.1 0.1 0.3 0.3 -0.5 0.3 -0.1 -0.2 -0.4 -0.2 0.4
Body mass index (BMI) 0.2 0.9 2.5 0.4 1.0 1.6 -0.2 1.1 1.1 -0.6 -0.7
Impedance of leg (left) 0.0 0.2 0.7 -0.4 0.0 -0.6 0.3 0.1 0.5 0.0 -0.8
Leg predicted mass (left) 0.2 0.8 3.5 0.6 0.6 1.9 -0.6 0.4 0.7 -1.1 -0.1
Trunk fat mass 0.1 0.3 1.2 -0.3 0.5 1.1 0.2 0.4 0.9 -0.2 -0.0
Waist circumference 0.1 0.3 0.8 -0.9 -0.2 0.9 0.3 -0.2 -0.0 0.5 0.5
Number of incorrect matches in round 0.2 0.4 0.9 -0.4 0.4 -0.7 -0.1 0.8 0.9 0.7 -0.7
Past tobacco smoking 7.2 13.2 25.2 -1.8 -4.1 -3.7 1.2 -4.4 -3.7 3.5 5.0
Alcohol usually taken with meals 1.6 2.6 5.5 0.9 -1.8 -1.0 1.5 -2.1 -1.6 0.9 2.3
Nervous feelings 0.2 0.3 1.4 -1.2 -0.0 -0.9 0.3 -0.2 -0.5 -0.2 0.2
Frequency of tenseness / restlessness in last 2 weeks 0.3 0.4 1.1 -0.9 -0.7 -0.6 -0.1 -1.1 -0.6 -0.1 0.6
Hearing difficulty/problems with background noise 4.0 6.4 11.2 1.5 3.4 1.9 -1.1 3.1 3.1 -2.1 -3.0
Hair/balding pattern: Pattern 2 1.2 1.5 2.8 1.7 1.1 0.4 -0.8 1.1 1.6 -1.5 -1.1
Had menopause 0.5 0.6 2.3 0.3 -0.6 -0.5 1.5 -0.0 0.2 1.3 0.8
Had other major operations 1.8 2.2 5.5 -0.2 1.8 0.6 -2.3 1.6 1.2 -1.2 -1.8
Forced vital capacity (FVC) 2.7 10.2 16.8 0.9 3.6 4.1 -2.4 3.3 2.8 -3.5 -3.7
Heel bone mineral density (BMD) T-score, automated (right) 0.2 0.4 1.5 -1.2 0.5 -0.7 -0.6 0.2 0.6 0.6 -0.2
Ever unenthusiastic/disinterested for a whole week 0.5 0.6 1.4 -0.1 0.8 -0.9 -0.6 0.5 0.7 -1.2 -0.8
Qualifications: None of the above 4.6 9.8 17.6 0.7 3.7 3.1 -2.9 3.9 3.3 -1.7 -4.2
Financial difficulties in last 2 years 1.2 1.6 3.8 2.0 0.6 1.5 -1.1 0.9 1.1 -1.2 -1.2
Mouth/teeth dental problems 0.7 1.1 2.5 -1.6 -0.6 -1.2 -0.9 -1.2 -1.1 0.4 1.0
Heart attack 0.7 0.9 3.9 -1.3 0.3 -2.0 -1.1 0.2 -0.4 0.0 -0.4
Allergy 0.3 0.6 1.4 0.5 0.6 1.0 0.3 0.8 1.2 -0.5 -0.9
Pain all over the body in last month 0.4 0.4 0.9 1.0 -0.9 -0.6 -0.6 -0.9 -0.1 -0.2 0.5
Diabetes (self-reported) 6.1 9.4 17.5 -4.2 -3.2 -2.3 -0.2 -3.4 -2.8 3.2 3.6
Hayfever/allergic rhinitis (self-reported) 1.1 1.4 3.0 -0.4 -1.3 -1.2 -0.3 -1.3 -1.7 0.8 1.7
Medication: Ramipril 1.1 1.5 4.1 -2.0 -1.2 -0.0 0.7 -1.2 -1.5 -0.6 1.2
Medication: Simvastatin 1.1 1.6 3.9 -1.5 -1.0 -2.0 1.0 -0.6 -1.2 1.3 1.0
Fluid intelligence score 7.8 16.3 31.9 -0.7 -5.0 -3.4 2.9 -4.9 -4.6 2.8 5.7
Illnesses of siblings 2.1 2.9 4.2 -1.8 -1.6 -1.6 1.4 -2.0 -2.0 1.4 1.8
Neuroticism score 0.5 1.1 2.7 -0.3 1.6 0.4 -0.7 1.2 1.1 -0.8 -1.4
Weight 0.2 0.8 3.8 0.2 0.7 1.9 -0.3 0.5 1.0 -0.7 -0.1
Impedance of arm (right) 0.3 1.6 2.8 -0.8 -1.6 -1.7 1.6 -1.3 -1.1 0.7 0.9
Arm fat percentage (right) 0.1 0.3 1.0 0.1 0.1 0.9 1.0 0.3 0.5 -0.4 -0.0
Trunk fat-free mass 0.3 1.7 5.5 1.1 1.0 2.3 -1.0 0.7 1.4 -1.5 -0.5
Hip circumference 0.1 0.3 1.3 -0.3 -0.2 1.1 0.6 -0.1 -0.2 0.4 0.7
Time employed in main current job 1.2 1.4 3.6 1.9 -0.9 -1.5 0.7 -1.1 -0.7 0.5 1.5
Alcohol intake versus 10 years previously 0.5 0.7 1.7 -1.3 0.2 1.1 -1.0 0.9 0.3 -0.3 -0.7
Father’s age at death 2.5 3.3 6.1 -1.1 -1.8 -2.4 1.6 -1.7 -1.8 1.4 2.5
Worrier / anxious feelings 0.4 0.8 2.6 -0.6 0.9 0.5 -1.6 0.7 0.8 -0.2 -0.9
Frequency of tiredness / lethargy in last 2 weeks 0.2 0.3 1.5 -1.2 -0.0 -0.0 0.1 -0.5 -0.4 -0.5 0.2
Falls in the last year 1.0 1.4 2.9 -0.3 1.6 0.4 -0.5 1.6 1.7 -1.2 -1.1
Hair/balding pattern: Pattern 3 0.5 0.8 1.8 -1.3 -0.1 0.9 -1.2 -0.2 -0.6 1.1 0.5
Number of live births 5.4 7.7 13.4 1.5 3.2 2.8 -0.8 3.4 3.2 -2.3 -3.7
Forced expiratory volume in 1-second (FEV1) 2.8 9.6 14.4 1.0 3.4 3.8 -2.0 3.2 2.8 -3.8 -3.7
Pulse rate 0.1 0.1 0.3 -0.1 0.4 0.5 0.5 0.2 0.5 0.4 0.1
Happiness 0.8 0.9 1.8 0.8 1.1 -0.5 0.6 1.0 0.9 -1.1 -1.3
Noisy workplace 0.7 0.8 1.9 -1.4 1.0 -0.3 -0.8 0.8 0.5 -0.0 -1.3
Qualifications: A levels/AS levels or equivalent 2.5 5.6 10.2 1.7 -2.7 -2.2 2.1 -2.9 -2.4 0.9 3.2
Serious illness, injury or assault of a close relative in last 2 years 1.0 1.1 2.0 -1.2 -0.7 -1.0 1.1 -0.9 -1.4 0.8 1.2
Mouth/teeth dental problems: Dentures 0.1 0.2 0.4 -0.1 0.3 0.6 -0.5 0.4 0.3 0.5 -0.2
Asthma 0.3 0.6 1.9 -0.6 0.8 0.8 -1.4 0.5 0.4 -0.1 -0.8
Medication: Ibuprofen (e.g. Nurofen) 0.1 0.2 0.6 0.8 0.1 0.7 -0.5 0.3 0.2 -0.2 -0.3
Medication: Cholesterol lowering 2.2 3.4 7.1 -2.7 -1.5 -2.4 0.4 -1.3 -2.0 2.0 1.6
Depression (self-reported) 0.9 1.1 2.5 -0.5 -1.3 -0.6 0.8 -1.4 -1.3 -0.0 1.6
Medication: Lansoprazole 0.8 0.9 1.4 -0.7 1.1 1.0 -1.1 1.0 1.1 -0.3 -1.2
Prospective memory result 0.3 0.4 1.0 0.7 0.3 -0.2 -1.0 0.3 0.4 -0.9 -0.7
Lung cancer (father) 0.6 0.7 2.4 -1.6 0.3 -0.2 -0.6 0.2 0.1 -1.5 -0.7
Illnesses of mother 0.6 0.7 1.5 0.8 0.9 -0.8 1.2 0.6 1.0 -0.1 -0.8
Forced expiratory volume in 1-second (FEV1), Best measure 2.3 7.4 11.9 1.9 2.9 3.5 -1.3 2.6 2.5 -3.4 -3.0
Pulse wave Arterial Stiffness index 3.6 4.2 9.0 0.1 -2.2 -2.6 1.5 -2.3 -1.1 2.2 3.0
Impedance of arm (left) 0.7 3.2 5.1 -1.6 -2.2 -2.0 1.7 -2.0 -1.8 1.4 1.6
Arm fat mass (right) 0.1 0.4 1.8 0.1 0.4 1.4 0.4 0.5 0.8 -0.8 -0.1
Trunk predicted mass 0.3 1.8 5.4 1.1 1.0 2.3 -1.0 0.8 1.5 -1.6 -0.5
Standing height 0.1 0.7 1.9 -0.8 -0.8 0.8 -0.4 -1.2 -0.2 0.0 1.4
Length of working week for main job 1.0 1.2 1.9 -1.0 -1.3 -0.9 0.0 -1.4 -1.3 0.4 1.3
Exposure to tobacco smoke at home 2.6 2.9 5.5 -0.7 2.0 1.0 -2.4 1.6 1.9 -1.1 -2.2
Breastfed as a baby 0.4 0.5 1.1 -0.9 -0.9 -0.7 0.4 -0.7 0.1 0.7 1.0
Tense / ‘highly strung’ 0.7 1.1 2.6 -0.3 1.4 1.1 -0.6 1.0 1.2 -0.5 -1.6
Seen doctor (GP) for nerves, anxiety, tension or depression 1.7 2.5 4.7 -0.9 2.2 0.8 -0.7 1.8 1.7 -2.0 -1.9
Hair/balding pattern: Pattern 4 0.4 0.9 1.5 -0.1 -1.0 -1.1 0.9 -1.0 -0.8 1.0 1.2
Birth weight of first child 0.8 1.4 7.9 -2.8 0.7 0.1 -1.5 0.4 0.1 0.7 0.2
Peak expiratory flow (PEF) 0.1 0.1 0.3 0.0 -0.1 0.2 -0.4 -0.3 -0.5 -0.5 0.5
Pulse wave reflection index 1.6 1.9 4.3 -0.6 -1.4 -2.1 1.3 -1.3 -0.9 1.7 1.5
Ever highly irritable/argumentative for 2 days 0.8 1.0 4.4 -2.1 -0.3 -1.1 -0.9 -0.5 -0.4 0.9 0.4
Loud music exposure frequency 1.1 1.3 2.3 0.2 1.5 0.2 -0.8 0.9 1.5 -1.4 -1.4
Qualifications: O levels/GCSEs or equivalent 1.2 1.9 3.8 0.9 -1.4 -1.9 1.8 -1.4 -1.3 -0.3 1.4
Mouth/teeth dental problems: Bleeding gums 1.1 1.4 2.9 0.1 1.1 0.9 -1.1 1.4 1.7 -0.9 -1.5
Blood clot in the leg (DVT) 0.3 0.3 1.3 -0.2 0.2 -1.1 -1.2 0.0 -0.0 0.2 -0.2
Medication: Paracetamol 2.2 3.6 7.4 1.4 2.3 1.4 -0.4 2.7 2.3 -1.2 -2.3
Headache pain in last month 0.4 0.7 1.3 0.8 0.9 0.5 0.7 1.0 0.6 -1.0 -1.1
Medication for cholesterol, blood pressure or diabetes 3.0 4.9 8.8 3.0 2.2 2.0 -0.2 1.9 2.5 -2.4 -2.5
Glaucoma (self-reported) 2.0 2.4 7.3 -2.5 -0.4 -2.7 -1.6 -0.4 -0.9 1.1 0.7
Gout (self-reported) 0.9 1.3 4.9 2.2 0.6 0.5 1.5 0.4 0.7 -1.0 -0.9
Hypothyroidism/myxoedema (self-reported) 0.2 0.3 0.6 0.5 0.6 -0.1 0.1 0.8 0.5 -0.6 -0.7
Medication: Amlodipine 0.7 1.0 3.7 -0.8 -0.4 -1.9 -0.8 -0.4 -0.4 1.5 0.6
Medication: Ventolin 100micrograms inhaler 1.7 2.2 4.4 -1.2 1.5 2.0 -2.1 1.2 1.4 -0.5 -1.5
Birth weight 0.3 0.7 2.0 0.4 -1.2 0.3 0.4 -0.9 -0.6 0.6 1.4
Chronic bronchitis/emphysema (mother) 0.9 1.0 3.5 1.6 0.4 0.7 -0.6 0.4 0.6 -1.9 -0.6
High blood pressure (siblings) 0.2 0.2 0.6 0.8 0.4 0.4 0.2 0.6 0.1 -0.7 -0.1
Forced vital capacity (FVC), Best measure 2.8 10.1 15.2 1.2 3.6 3.9 -2.5 3.2 3.0 -3.5 -3.6
Body fat percentage 0.1 0.3 0.7 -0.3 0.5 0.8 0.6 0.5 0.8 -0.1 -0.2
Leg fat percentage (right) 0.2 0.9 1.8 -0.1 1.1 1.2 0.3 1.1 1.3 -0.2 -1.0
Arm fat-free mass (right) 0.2 1.1 3.9 0.9 0.9 2.0 -0.9 0.5 1.2 -1.1 -0.2
Exposure to tobacco smoke outside home 0.2 0.3 0.9 -0.3 -0.0 0.5 -0.9 -0.5 0.1 0.7 0.5
Comparative body size at age 10 0.1 0.3 0.8 0.6 -0.2 0.6 -0.9 -0.2 -0.4 -0.5 0.6
Number of full brothers 6.4 8.1 14.9 1.4 3.2 2.2 -1.3 3.2 3.7 -2.6 -3.9
Worry too long after embarrassment 0.3 0.5 1.4 0.7 1.2 0.1 -0.7 0.8 0.9 -0.3 -0.6
Seen a psychiatrist for nerves, anxiety, tension or depression 1.4 1.9 4.6 0.0 1.4 1.4 0.2 1.4 1.0 -2.1 -1.9
Wheeze or whistling in the chest in last year 0.4 0.8 2.9 -0.5 0.6 0.9 -1.7 0.9 0.5 -0.1 -0.7
Number of children fathered 1.1 1.3 3.3 0.7 1.3 -0.5 -0.5 1.5 1.8 -0.6 -1.2
Reason for reducing amount of alcohol drunk: Health precaution 1.2 1.5 3.3 -0.3 1.6 -0.0 -1.0 1.5 1.8 -0.3 -1.6
Age at first live birth 4.0 7.0 13.5 -0.6 -3.7 -2.1 2.2 -3.4 -3.2 0.5 3.3
Pulse wave peak to peak time 3.0 3.5 7.0 -0.3 2.0 2.6 -1.3 1.9 0.9 -2.1 -2.7
Health satisfaction 0.4 0.5 0.8 0.9 0.7 0.1 0.2 0.8 0.9 -0.7 -0.7
Shortness of breath walking on level ground 2.4 2.9 5.4 -0.1 1.8 1.0 -0.8 1.9 2.2 -2.3 -2.1
Qualifications: College or University degree 6.0 19.0 33.1 -0.5 -5.0 -4.3 3.9 -5.3 -5.1 2.2 5.8
Eye problems/disorders: None of the above 1.7 2.0 4.8 1.7 1.3 2.2 -0.3 1.3 1.4 -1.0 -1.4
Mouth/teeth dental problems: Loose teeth 1.3 1.5 5.8 2.4 0.5 1.1 1.6 0.6 0.8 -0.9 -0.7
Emphysema/chronic bronchitis 2.1 2.3 4.1 1.6 1.4 1.9 -0.2 1.6 2.0 -1.3 -1.5
Medication for pain relief, constipation, heartburn 0.3 0.6 1.5 -0.0 -0.8 -0.5 0.4 -1.2 -0.9 -0.6 0.9
Neck or shoulder pain in last month 0.6 0.8 2.4 -0.5 -0.7 -0.6 0.5 -0.6 -1.0 1.6 1.2
Medication: Blood pressure 0.5 0.9 3.2 -1.8 -0.5 -0.9 0.1 -0.4 -1.0 1.1 0.9
Angina (self-reported) 0.2 0.2 1.0 0.2 -0.3 -0.1 0.8 -0.2 -1.0 -0.1 0.3
Migraine (self-reported) 4.0 5.0 8.9 1.5 2.7 2.1 -0.8 2.4 2.4 -2.2 -3.0
Medication: Ibuprofen 0.2 0.2 0.6 0.7 0.3 0.8 -0.2 0.4 0.1 -0.6 -0.5
Medication: Allopurinol 0.3 0.4 1.6 1.3 0.0 1.1 0.2 -0.2 0.2 -0.7 -0.2
Medication: Omeprazole 1.3 1.6 3.0 -0.1 1.5 0.6 -1.2 1.6 1.6 -0.6 -1.7
Medication: Seretide 50 evohaler 1.2 1.3 2.2 0.6 1.1 1.1 -1.5 1.0 1.1 -1.3 -1.3
Mean time to correctly identify matches 4.5 8.7 17.8 1.2 3.9 0.5 -1.2 3.6 4.0 -2.2 -4.2
Heart disease (mother) 0.3 0.3 1.1 -0.7 -0.6 0.5 -0.0 -0.5 -1.0 -0.1 0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.8 2.2 5.2 0.6 2.1 -0.3 0.2 1.9 1.7 -0.7 -2.3
Whole body fat mass 0.1 0.4 1.8 -0.1 0.5 1.3 0.3 0.5 0.9 -0.3 -0.1
Leg fat mass (right) 0.3 1.1 2.5 0.3 1.2 1.6 -0.1 1.1 1.6 -0.7 -0.9
Arm predicted mass (right) 0.2 1.0 3.1 0.8 0.9 1.8 -0.9 0.5 1.1 -1.0 -0.3
Pulse rate, automated reading 0.4 1.3 1.9 -1.3 -0.8 -0.9 1.1 -1.2 -0.7 1.4 1.3
Alcohol intake frequency. 0.2 0.5 1.6 1.2 -0.1 0.6 1.1 0.4 -0.4 -0.7 -0.1
Comparative height size at age 10 0.1 0.7 1.3 0.9 0.6 1.1 1.1 0.4 1.1 -0.8 -0.1
Number of full sisters 4.1 4.9 7.4 2.4 2.4 1.3 -1.2 2.3 2.3 -2.7 -2.7
Suffer from ‘nerves’ 0.3 0.5 1.7 -1.3 0.9 -0.4 -0.0 0.5 -0.7 -0.0 -0.7
Overall health rating 0.2 0.4 1.1 0.8 0.3 1.0 0.5 0.5 0.4 -0.6 -0.6
Chest pain or discomfort 0.2 0.3 1.5 -0.6 0.2 0.1 -1.2 0.1 0.3 -0.3 -0.7
Had major operations 1.0 1.2 4.0 0.5 0.1 2.0 -0.5 0.2 0.9 -1.8 -0.9
Age at last live birth 0.9 1.3 2.6 -0.8 -1.6 -0.5 0.5 -1.4 -1.6 -0.7 1.3
Family relationship satisfaction 2.1 2.5 6.0 -0.7 2.1 1.1 -0.3 1.8 2.0 -1.1 -2.5
Leg pain on walking 0.4 0.5 1.5 -0.1 0.7 0.5 -0.1 0.8 0.7 -1.2 -0.9
Qualifications: NVQ or HND or HNC or equivalent 4.0 4.9 9.2 0.5 3.0 1.3 -0.8 2.7 2.6 -2.1 -3.0
Commuting to job workplace: Car/motor vehicle 2.2 2.5 5.2 -0.4 2.2 0.2 -1.1 2.2 1.8 -0.3 -2.3
Illness, injury, bereavement, stress in last 2 years 0.2 0.3 1.0 -1.0 -0.0 0.6 -0.4 -0.2 0.2 0.7 0.3
Medication: Aspirin 0.6 0.8 1.5 -0.7 -0.9 -0.0 1.2 -0.7 -0.9 1.0 1.0
Supplements: Vitamin C 0.8 0.9 2.2 -1.5 -0.8 -0.8 -1.2 -0.9 -0.7 0.6 0.8
Knee pain experienced in last month 0.6 1.0 1.9 1.2 1.1 1.4 -0.1 0.9 0.8 -1.0 -0.8
Hypertension (Self-reported) 1.4 4.0 9.8 -3.1 -1.4 -1.4 -1.1 -1.4 -2.1 2.4 2.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.9 1.1 2.4 -0.5 0.8 1.6 -0.8 0.8 1.2 -1.1 -1.2
Illnesses of father: Heart disease 1.0 1.4 2.6 1.5 1.1 1.6 -0.6 1.2 1.3 -0.8 -0.9
Illnesses of siblings: Diabetes 0.6 0.7 1.5 1.2 0.3 1.2 -0.5 0.9 1.1 -0.2 -0.7
Smoking status: Previous 7.6 11.3 22.1 1.4 3.7 3.4 -1.7 4.0 3.5 -3.3 -4.7
Forced expiratory volume in 1-second (FEV1), predicted 0.3 0.7 2.8 -1.7 -0.1 0.3 -0.9 -0.6 -0.8 -0.9 -0.1
Whole body fat-free mass 0.2 1.4 4.5 1.1 0.9 2.1 -0.8 0.6 1.2 -1.5 -0.3
Leg fat-free mass (right) 0.1 0.6 2.3 0.7 0.4 1.5 -0.5 0.1 0.4 -1.1 0.3
Arm fat percentage (left) 0.1 0.2 1.1 -0.1 -0.1 0.6 1.0 0.1 0.3 -0.1 0.2
Average weekly red wine intake 1.7 2.6 5.9 -0.3 -1.7 -1.0 1.0 -2.1 -1.2 1.9 2.4
Handedness (chirality/laterality): Left-handed 3.3 4.0 8.9 2.0 2.5 0.5 -0.4 2.0 3.0 -1.5 -2.4
Mood swings 0.3 0.6 1.3 -0.1 1.2 0.6 -0.5 0.7 1.1 -0.5 -1.0
Loneliness, isolation 0.5 0.6 1.3 -1.1 -1.1 -0.1 -0.7 -1.0 -0.8 -0.0 0.7
Long-standing illness, disability or infirmity 0.1 0.2 0.7 -0.3 0.2 0.0 -0.4 0.4 -0.1 -0.8 -0.1
Ever had bowel cancer screening 2.3 2.7 6.7 -1.2 -1.8 -1.5 -0.2 -1.4 -1.2 2.6 2.0
Diabetes diagnosed by doctor 7.2 11.8 20.0 -4.5 -3.6 -2.9 -0.6 -3.6 -3.3 3.5 4.0
Ever had stillbirth, spontaneous miscarriage or termination 1.5 1.6 2.7 0.0 0.9 1.6 -1.2 1.2 1.1 -1.6 -1.6
Friendships satisfaction 1.2 1.5 4.4 0.8 -0.7 -2.1 1.9 -0.9 -1.1 -0.2 0.7
Qualifications: nursing, teaching 1.8 2.8 7.0 -0.8 -1.6 -2.6 0.9 -1.9 -1.9 0.9 1.9
Commuting to job workplace: Walk 3.5 3.8 9.2 1.3 -2.6 1.0 3.0 -2.0 -1.6 0.6 2.2
Eye problems/disorders: Cataract 0.9 1.0 2.1 0.2 1.3 0.6 0.1 1.4 1.3 -0.6 -1.3
Mouth/teeth dental problems: Mouth ulcers 0.7 1.1 3.8 2.0 -1.2 0.5 0.7 -0.7 -0.8 0.8 1.0
Medication for cholesterol 1.1 1.7 7.3 1.9 0.3 1.2 2.7 0.2 0.7 -0.9 -0.4
Medication: Laxatives (e.g. Dulcolax, Senokot) 3.0 3.5 6.5 0.9 1.6 1.9 -0.8 1.7 2.4 -2.6 -2.2
Back pain experienced in last month 0.2 0.2 0.7 0.9 0.6 -0.0 0.8 0.4 -0.0 -0.2 -0.3
Mineral and other dietary supplements 5.1 6.9 10.8 1.2 2.4 2.6 -2.9 2.4 2.5 -3.1 -3.3
Breast cancer (self-reported) 1.4 1.7 3.1 0.7 1.7 -0.2 0.7 1.8 1.7 -0.4 -1.8
Asthma (self-reported) 0.4 0.8 1.6 -0.6 1.0 0.9 -1.3 0.7 0.6 -0.4 -1.2
Osteoporosis (self-reported) 1.8 2.2 4.5 -0.1 -1.8 -0.6 1.7 -1.4 -1.5 1.6 2.1
Osteoarthritis (self-reported) 1.4 1.8 3.5 1.7 1.1 1.2 -0.8 1.3 1.9 -0.3 -1.5
Medication: Aspirin 0.8 1.1 1.8 -1.3 -1.0 -0.5 0.9 -0.7 -1.0 1.3 1.2
Medication: Gliclazide 1.8 2.0 7.2 -2.7 -1.3 -0.3 -0.1 -1.3 -1.2 1.7 1.1
Illnesses of father: None of the above (group 1) 0.9 1.1 2.7 -0.1 1.7 0.7 -0.7 1.3 1.2 -0.6 -1.4
Smoking status: Current 0.3 0.4 1.3 1.0 0.6 -0.0 1.1 0.5 0.3 -0.4 -0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage 2.2 4.6 7.7 1.1 2.7 1.3 -1.1 2.6 2.6 -2.0 -2.8
Whole body water mass 0.2 1.4 4.5 1.0 0.9 2.1 -0.9 0.6 1.2 -1.4 -0.3
Leg predicted mass (right) 0.1 0.5 2.1 0.7 0.3 1.4 -0.4 0.1 0.4 -1.0 0.4
Arm fat mass (left) 0.1 0.3 1.1 0.0 0.4 1.1 0.4 0.4 0.7 -0.4 -0.0
Number of self-reported non-cancer illnesses 0.6 1.0 4.6 -2.1 -0.6 -0.3 -0.6 -0.6 -0.8 1.0 0.9
Average weekly champagne plus white wine intake 0.5 0.7 1.3 -0.9 -0.8 0.6 -0.4 -0.6 -1.1 0.7 1.1
Miserableness 0.3 0.5 1.5 -0.5 -0.7 -0.2 -0.2 -1.2 -1.1 -0.0 0.7
Guilty feelings 1.1 1.6 3.8 -0.1 1.9 -0.0 -1.2 1.3 1.5 -1.4 -1.5
Wears glasses or contact lenses 0.3 0.3 0.8 -0.7 -0.2 0.9 -0.7 0.2 0.3 0.2 0.7
Ever taken oral contraceptive pill 1.3 1.5 2.9 0.3 1.5 0.5 -1.1 1.1 1.2 -1.7 -1.6
Hearing aid user 0.8 0.9 3.4 -0.9 0.8 0.3 -1.8 1.1 0.2 -0.5 -1.0
Mother’s age at death 0.1 0.1 0.2 0.3 0.3 0.4 0.2 -0.0 0.4 -0.3 0.1
Financial situation satisfaction 4.6 5.7 8.9 1.8 2.7 2.0 -2.1 2.6 2.8 -1.7 -3.0
Tinnitus: Yes, now most or all of the time 3.0 3.5 6.6 -0.1 2.6 1.5 -1.3 2.5 2.2 -0.8 -2.4
Commuting to job workplace: Public transport 1.2 1.4 2.7 -0.3 -1.3 -1.0 0.7 -1.5 -1.3 1.0 1.6
Eye problems/disorders: Glaucoma 0.9 1.1 6.8 -1.1 0.0 -2.6 -0.4 -0.1 -0.5 0.4 0.2
Medication: Blood pressure 0.9 1.8 3.6 -1.4 -0.9 -1.3 -1.9 -0.7 -1.3 1.4 1.3
Pain type(s) experienced in last month: Hip pain 0.2 0.3 1.9 -1.4 0.1 -0.2 0.4 0.1 -0.1 0.4 0.3
Supplements: Fish oil (including cod liver oil) 1.9 2.4 6.6 0.1 -1.4 -1.2 2.6 -1.0 -1.4 1.8 1.8
High cholesterol (Self-reported) 0.2 0.3 0.6 -0.7 -0.7 -0.8 0.5 -0.4 -0.5 0.2 0.3
Medication: Bendroflumethiazide 1.9 2.8 3.9 -2.0 -1.5 -1.9 -1.4 -1.4 -1.7 1.9 1.6
Medication: Paracetamol 1.2 1.9 4.8 0.2 1.9 0.2 -0.4 2.2 1.6 -0.6 -1.8
Medication: Lisinopril 0.3 0.5 1.8 -1.0 0.0 0.2 -0.4 0.1 -0.7 1.3 0.4
Medication: Atorvastatin 0.6 0.8 2.4 -1.5 -1.0 0.2 0.0 -1.0 -0.9 0.0 0.9
Illnesses of father: High blood pressure 2.1 2.6 5.1 -0.9 -2.2 -1.5 -0.8 -1.9 -1.9 0.7 2.3
Alcohol drinker status: Never 0.4 0.5 1.5 1.2 0.3 0.0 1.2 0.6 0.2 0.6 0.0
Ever smoked 5.2 9.2 17.0 1.4 3.5 3.3 -1.0 3.7 3.3 -2.5 -4.1
Basal metabolic rate 0.2 1.3 4.8 0.8 0.9 2.2 -0.7 0.6 1.1 -1.4 -0.3
Leg fat percentage (left) 0.2 0.6 1.2 -0.1 0.9 1.0 0.3 1.0 1.1 -0.0 -0.6
Arm fat-free mass (left) 0.3 1.6 3.6 0.8 1.3 1.9 -1.2 0.9 1.5 -1.3 -0.7
Number of operations (self-reported) 1.8 2.7 4.9 0.4 1.7 1.4 -2.0 1.9 1.4 -1.6 -2.2
Average weekly beer plus cider intake 3.8 5.6 11.1 1.3 2.7 1.9 -1.7 2.7 2.6 -1.9 -3.3
Irritability 0.8 1.3 3.0 0.6 1.1 1.7 -0.8 1.1 1.3 -0.5 -1.4
Risk taking 0.3 0.4 1.6 1.3 -0.3 0.1 0.8 -0.1 0.6 0.5 0.1
Ever had prostate specific antigen (PSA) test 3.1 3.5 5.5 -0.9 -2.2 -1.9 0.3 -2.1 -2.0 2.3 2.2
Fractured/broken bones in last 5 years 0.7 0.9 3.2 -1.8 -0.9 0.5 -0.9 -0.7 -0.7 0.3 1.0
Age started oral contraceptive pill 2.3 2.9 6.5 -0.2 -2.3 -1.5 0.1 -1.8 -1.2 2.1 2.6
Diastolic blood pressure, automated reading 0.2 0.5 1.4 -0.9 0.4 0.3 -1.1 0.3 0.5 1.2 0.2
Ever depressed for a whole week 0.8 1.0 1.9 1.4 1.0 0.3 0.1 1.0 1.2 -1.1 -1.2
Unable to work because of sickness or disability 2.4 3.0 4.4 1.7 1.9 1.8 -0.7 1.7 2.1 -1.7 -2.0
Commuting to job workplace: Cycle 6.8 8.2 15.9 -1.6 -3.7 -2.5 1.4 -4.0 -3.3 0.4 3.7
Myopia 0.3 0.4 1.2 -0.6 0.5 0.0 -1.1 0.3 0.8 -0.8 -0.6
Vascular/heart problems diagnosed by doctor 1.1 3.0 9.1 3.0 1.2 0.9 1.1 1.1 1.8 -1.9 -1.8
Cholesterol lowering medication 0.2 0.3 1.2 -1.1 -0.5 -0.8 -0.4 -0.2 -0.2 0.4 0.4
Medication: Omeprazole (e.g. Zanprol) 0.7 0.8 1.7 -0.3 1.0 0.3 -1.3 0.9 1.2 -0.1 -1.2
Pain experienced in last month 0.9 1.4 4.1 -0.8 0.9 1.1 -2.0 1.1 1.2 -0.8 -1.3
Supplements: Calcium 1.8 2.0 5.1 -2.1 -0.6 -2.2 -0.5 -0.5 -0.7 2.1 1.0
Basal cell carcinoma (self-reported) 0.4 0.4 1.7 0.8 0.5 0.0 1.3 0.6 0.2 -0.7 -0.2
Heart attack/myocardial infarction (self-reported) 0.6 0.7 2.8 -0.8 0.6 -1.7 -0.9 0.6 -0.0 -0.2 -0.8
Deep venous thrombosis (DVT) (self-reported) 0.3 0.4 1.7 -0.4 -0.1 -1.1 -1.3 -0.2 -0.2 0.3 -0.1
Heart disease (siblings) 0.6 0.7 3.3 0.4 0.5 -0.7 -1.8 0.8 0.7 -0.0 -0.8
Alcohol drinker status: Previous 0.7 0.8 1.5 -1.2 -0.9 0.5 -0.4 -1.0 -0.9 0.8 1.0
Pack years of smoking 1.0 1.4 2.7 1.6 -1.1 -1.4 1.5 -1.4 -0.4 0.6 1.1
Impedance of whole body 0.4 1.8 2.9 -1.6 -1.6 -1.7 1.2 -1.4 -1.2 1.0 0.8
Leg fat mass (left) 0.2 0.9 2.1 0.2 1.1 1.4 -0.0 1.0 1.4 -0.6 -0.7
Arm predicted mass (left) 0.4 2.1 4.8 1.1 1.4 2.2 -1.2 1.1 1.6 -1.6 -0.8