TWAS hub - CYHR1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Esophagus Mucosa	0.0460	0.0240	5.3e-03	0.017	NA	0.019	NA	0.012	2.3e-02	NA	1.9e-02	NA	4.9e-02
2	GTEx	Nerve Tibial	0.0611	0.0282	2.6e-03	0.060	NA	0.021	NA	-0.003	4.6e-05	NA	1.2e-02	NA	6.1e-01
3	GTEx	Skin Sun Exposed Lower leg	0.0800	0.0360	1.6e-03	0.014	NA	0.040	NA	0.022	2.2e-02	NA	3.0e-04	NA	5.5e-03
4	GTEx	Spleen	0.1340	0.0700	8.3e-03	0.003	NA	-0.012	NA	-0.011	2.6e-01	NA	9.7e-01	NA	8.5e-01
5	GTEx	Thyroid	0.0760	0.0300	3.8e-04	0.096	NA	0.042	NA	0.004	8.7e-08	NA	3.5e-04	NA	1.5e-01
6	ROSMAP	Brain Pre-frontal Cortex	0.0859	0.0279	1.7e-10	0.082	0.072	0.101	0.06	0.040	9.2e-11	1.5e-09	5.9e-13	3.5e-08	5.4e-06
7	TCGA	Breast Invasive Carcinoma	0.0425	0.0236	8.0e-06	0.027	0.030	0.028	NA	0.027	2.1e-06	6.8e-07	1.8e-06	NA	2.9e-06
8	TCGA	Prostate Adenocarcinoma	0.0319	0.0212	3.6e-03	0.009	0.008	0.010	NA	0.012	3.3e-02	4.5e-02	2.8e-02	NA	1.7e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Age at First Birth	9.6	14.0	22.9	-0.4	-4.0	-3.9	3.5	-4.5	-4.1	2.9	4.8
Type 2 Diabetes (T2D) (2018)	8.5	15.9	25.0	-5.0	-4.3	-3.1	-0.7	-4.4	-4.2	4.2	4.3
Intelligence (Savage-Jansen 2018)	8.2	25.1	40.2	-0.4	-5.3	-6.3	4.2	-5.5	-5.5	4.5	5.7
Fluid intelligence score	7.8	16.3	31.9	-0.7	-5.0	-3.4	2.9	-4.9	-4.6	2.8	5.7
Smoking status: Previous	7.6	11.3	22.1	1.4	3.7	3.4	-1.7	4.0	3.5	-3.3	-4.7
Past tobacco smoking	7.2	13.2	25.2	-1.8	-4.1	-3.7	1.2	-4.4	-3.7	3.5	5.0
Diabetes diagnosed by doctor	7.2	11.8	20.0	-4.5	-3.6	-2.9	-0.6	-3.6	-3.3	3.5	4.0
Verbal and Numeric Reasoning (VNR)	6.8	16.4	26.1	1.1	-4.6	-4.5	3.9	-4.6	-4.3	2.9	5.1
Commuting to job workplace: Cycle	6.8	8.2	15.9	-1.6	-3.7	-2.5	1.4	-4.0	-3.3	0.4	3.7
Reaction Time	6.5	12.4	22.5	1.6	4.5	1.8	-0.9	4.3	4.4	-3.4	-4.7
Average weekly spirits intake	6.4	7.9	16.7	0.1	3.4	2.3	-1.8	3.2	3.2	-2.5	-4.1
Number of full brothers	6.4	8.1	14.9	1.4	3.2	2.2	-1.3	3.2	3.7	-2.6	-3.9
Diabetes (self-reported)	6.1	9.4	17.5	-4.2	-3.2	-2.3	-0.2	-3.4	-2.8	3.2	3.6
Qualifications: College or University degree	6.0	19.0	33.1	-0.5	-5.0	-4.3	3.9	-5.3	-5.1	2.2	5.8
Number of live births	5.4	7.7	13.4	1.5	3.2	2.8	-0.8	3.4	3.2	-2.3	-3.7
Ever smoked	5.2	9.2	17.0	1.4	3.5	3.3	-1.0	3.7	3.3	-2.5	-4.1
Mineral and other dietary supplements	5.1	6.9	10.8	1.2	2.4	2.6	-2.9	2.4	2.5	-3.1	-3.3
Qualifications: None of the above	4.6	9.8	17.6	0.7	3.7	3.1	-2.9	3.9	3.3	-1.7	-4.2
Financial situation satisfaction	4.6	5.7	8.9	1.8	2.7	2.0	-2.1	2.6	2.8	-1.7	-3.0
Lung FVC	4.5	22.9	36.9	3.0	6.1	4.1	-2.5	5.6	5.2	-5.1	-5.4
Mean time to correctly identify matches	4.5	8.7	17.8	1.2	3.9	0.5	-1.2	3.6	4.0	-2.2	-4.2
Smoking Status	4.4	10.4	17.6	2.0	3.7	3.2	0.0	3.7	3.2	-3.7	-4.2
Qualifications: CSEs or equivalent	4.2	5.5	10.6	-0.1	2.4	2.3	-1.8	2.2	2.3	-3.1	-3.3
Number of full sisters	4.1	4.9	7.4	2.4	2.4	1.3	-1.2	2.3	2.3	-2.7	-2.7
Hearing difficulty/problems with background noise	4.0	6.4	11.2	1.5	3.4	1.9	-1.1	3.1	3.1	-2.1	-3.0
Age at first live birth	4.0	7.0	13.5	-0.6	-3.7	-2.1	2.2	-3.4	-3.2	0.5	3.3
Migraine (self-reported)	4.0	5.0	8.9	1.5	2.7	2.1	-0.8	2.4	2.4	-2.2	-3.0
Qualifications: NVQ or HND or HNC or equivalent	4.0	4.9	9.2	0.5	3.0	1.3	-0.8	2.7	2.6	-2.1	-3.0
Average weekly beer plus cider intake	3.8	5.6	11.1	1.3	2.7	1.9	-1.7	2.7	2.6	-1.9	-3.3
Medication: Metformin	3.7	5.3	12.1	-3.5	-2.1	-1.6	-1.6	-2.2	-2.4	1.9	2.5
Eye problems/disorders: Diabetes related eye disease	3.6	4.0	6.7	-2.3	-2.4	-1.2	-0.0	-2.1	-2.1	2.0	2.6
Pulse wave Arterial Stiffness index	3.6	4.2	9.0	0.1	-2.2	-2.6	1.5	-2.3	-1.1	2.2	3.0
Commuting to job workplace: Walk	3.5	3.8	9.2	1.3	-2.6	1.0	3.0	-2.0	-1.6	0.6	2.2
Supplements: Glucosamine	3.4	4.4	6.7	-1.5	-2.1	-2.5	1.1	-2.2	-2.0	2.4	2.6
Handedness (chirality/laterality): Left-handed	3.3	4.0	8.9	2.0	2.5	0.5	-0.4	2.0	3.0	-1.5	-2.4
Cardiovascular Disease	3.2	10.7	17.5	-3.8	-3.2	-2.5	-0.5	-3.1	-4.2	3.9	3.4
Ever had prostate specific antigen (PSA) test	3.1	3.5	5.5	-0.9	-2.2	-1.9	0.3	-2.1	-2.0	2.3	2.2
Severe depression (siblings)	3.0	3.4	5.7	2.4	2.2	1.0	-0.7	2.1	2.0	-1.3	-2.3
Multivitamins +/- minerals	3.0	3.8	8.0	-1.4	-2.3	-0.8	1.3	-2.0	-2.0	2.3	2.8
Medication for cholesterol, blood pressure or diabetes	3.0	4.9	8.8	3.0	2.2	2.0	-0.2	1.9	2.5	-2.4	-2.5
Pulse wave peak to peak time	3.0	3.5	7.0	-0.3	2.0	2.6	-1.3	1.9	0.9	-2.1	-2.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	3.0	3.5	6.5	0.9	1.6	1.9	-0.8	1.7	2.4	-2.6	-2.2
Tinnitus: Yes, now most or all of the time	3.0	3.5	6.6	-0.1	2.6	1.5	-1.3	2.5	2.2	-0.8	-2.4
Forced expiratory volume in 1-second (FEV1)	2.8	9.6	14.4	1.0	3.4	3.8	-2.0	3.2	2.8	-3.8	-3.7
Forced vital capacity (FVC), Best measure	2.8	10.1	15.2	1.2	3.6	3.9	-2.5	3.2	3.0	-3.5	-3.6
Forced vital capacity (FVC)	2.7	10.2	16.8	0.9	3.6	4.1	-2.4	3.3	2.8	-3.5	-3.7
Frequency of unenthusiasm / disinterest in last 2 weeks	2.6	3.5	9.9	0.4	1.8	2.0	-1.2	1.4	1.7	-3.1	-2.0
Exposure to tobacco smoke at home	2.6	2.9	5.5	-0.7	2.0	1.0	-2.4	1.6	1.9	-1.1	-2.2
Hearing difficulty/problems: Yes	2.5	3.8	6.8	1.3	2.6	1.8	-1.1	2.6	2.3	-0.9	-2.2
Father’s age at death	2.5	3.3	6.1	-1.1	-1.8	-2.4	1.6	-1.7	-1.8	1.4	2.5
Qualifications: A levels/AS levels or equivalent	2.5	5.6	10.2	1.7	-2.7	-2.2	2.1	-2.9	-2.4	0.9	3.2
Shortness of breath walking on level ground	2.4	2.9	5.4	-0.1	1.8	1.0	-0.8	1.9	2.2	-2.3	-2.1
Unable to work because of sickness or disability	2.4	3.0	4.4	1.7	1.9	1.8	-0.7	1.7	2.1	-1.7	-2.0
Prostate Cancer	2.3	3.2	5.4	0.5	2.1	1.2	-1.7	1.8	2.1	-1.7	-2.3
Sensitivity / hurt feelings	2.3	4.0	7.7	1.2	2.8	-0.6	-1.2	2.4	2.5	-1.5	-2.6
Forced expiratory volume in 1-second (FEV1), Best measure	2.3	7.4	11.9	1.9	2.9	3.5	-1.3	2.6	2.5	-3.4	-3.0
Ever had bowel cancer screening	2.3	2.7	6.7	-1.2	-1.8	-1.5	-0.2	-1.4	-1.2	2.6	2.0
Age started oral contraceptive pill	2.3	2.9	6.5	-0.2	-2.3	-1.5	0.1	-1.8	-1.2	2.1	2.6
Medication: Cholesterol lowering	2.2	3.4	7.1	-2.7	-1.5	-2.4	0.4	-1.3	-2.0	2.0	1.6
Medication: Paracetamol	2.2	3.6	7.4	1.4	2.3	1.4	-0.4	2.7	2.3	-1.2	-2.3
Commuting to job workplace: Car/motor vehicle	2.2	2.5	5.2	-0.4	2.2	0.2	-1.1	2.2	1.8	-0.3	-2.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.2	4.6	7.7	1.1	2.7	1.3	-1.1	2.6	2.6	-2.0	-2.8
Illnesses of siblings	2.1	2.9	4.2	-1.8	-1.6	-1.6	1.4	-2.0	-2.0	1.4	1.8
Emphysema/chronic bronchitis	2.1	2.3	4.1	1.6	1.4	1.9	-0.2	1.6	2.0	-1.3	-1.5
Family relationship satisfaction	2.1	2.5	6.0	-0.7	2.1	1.1	-0.3	1.8	2.0	-1.1	-2.5
Illnesses of father: High blood pressure	2.1	2.6	5.1	-0.9	-2.2	-1.5	-0.8	-1.9	-1.9	0.7	2.3
Glaucoma (self-reported)	2.0	2.4	7.3	-2.5	-0.4	-2.7	-1.6	-0.4	-0.9	1.1	0.7
Bilateral oophorectomy (both ovaries removed)	1.9	2.2	4.1	-2.0	1.1	-1.8	-1.9	0.9	0.5	2.0	-0.5
Supplements: Fish oil (including cod liver oil)	1.9	2.4	6.6	0.1	-1.4	-1.2	2.6	-1.0	-1.4	1.8	1.8
Medication: Bendroflumethiazide	1.9	2.8	3.9	-2.0	-1.5	-1.9	-1.4	-1.4	-1.7	1.9	1.6
Ulcerative Colitis	1.8	2.6	5.3	-0.7	-2.0	-1.4	2.3	-1.7	-2.1	1.2	0.0
Had other major operations	1.8	2.2	5.5	-0.2	1.8	0.6	-2.3	1.6	1.2	-1.2	-1.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.8	2.2	5.2	0.6	2.1	-0.3	0.2	1.9	1.7	-0.7	-2.3
Qualifications: nursing, teaching	1.8	2.8	7.0	-0.8	-1.6	-2.6	0.9	-1.9	-1.9	0.9	1.9
Osteoporosis (self-reported)	1.8	2.2	4.5	-0.1	-1.8	-0.6	1.7	-1.4	-1.5	1.6	2.1
Medication: Gliclazide	1.8	2.0	7.2	-2.7	-1.3	-0.3	-0.1	-1.3	-1.2	1.7	1.1
Number of operations (self-reported)	1.8	2.7	4.9	0.4	1.7	1.4	-2.0	1.9	1.4	-1.6	-2.2
Supplements: Calcium	1.8	2.0	5.1	-2.1	-0.6	-2.2	-0.5	-0.5	-0.7	2.1	1.0
Schizophrenia vs Biploar Disorder	1.7	2.2	3.8	1.2	1.8	2.0	-1.6	1.6	1.6	-1.1	0.0
Vitamin and mineral supplements	1.7	2.4	4.3	1.5	1.8	0.5	-0.6	1.6	1.7	-1.9	-2.1
Maternal smoking around birth	1.7	2.5	9.1	0.1	1.5	1.1	-1.3	1.2	1.2	-3.0	-1.7
Seen doctor (GP) for nerves, anxiety, tension or depression	1.7	2.5	4.7	-0.9	2.2	0.8	-0.7	1.8	1.7	-2.0	-1.9
Medication: Ventolin 100micrograms inhaler	1.7	2.2	4.4	-1.2	1.5	2.0	-2.1	1.2	1.4	-0.5	-1.5
Eye problems/disorders: None of the above	1.7	2.0	4.8	1.7	1.3	2.2	-0.3	1.3	1.4	-1.0	-1.4
Average weekly red wine intake	1.7	2.6	5.9	-0.3	-1.7	-1.0	1.0	-2.1	-1.2	1.9	2.4
Hayfever, allergic rhinitis or eczema	1.6	3.6	5.8	0.2	-2.0	-2.1	1.7	-2.2	-2.4	0.8	2.4
Alcohol usually taken with meals	1.6	2.6	5.5	0.9	-1.8	-1.0	1.5	-2.1	-1.6	0.9	2.3
Pulse wave reflection index	1.6	1.9	4.3	-0.6	-1.4	-2.1	1.3	-1.3	-0.9	1.7	1.5
Ever had stillbirth, spontaneous miscarriage or termination	1.5	1.6	2.7	0.0	0.9	1.6	-1.2	1.2	1.1	-1.6	-1.6
Seen a psychiatrist for nerves, anxiety, tension or depression	1.4	1.9	4.6	0.0	1.4	1.4	0.2	1.4	1.0	-2.1	-1.9
Hypertension (Self-reported)	1.4	4.0	9.8	-3.1	-1.4	-1.4	-1.1	-1.4	-2.1	2.4	2.3
Breast cancer (self-reported)	1.4	1.7	3.1	0.7	1.7	-0.2	0.7	1.8	1.7	-0.4	-1.8
Osteoarthritis (self-reported)	1.4	1.8	3.5	1.7	1.1	1.2	-0.8	1.3	1.9	-0.3	-1.5
Alzheimer’s Disease (in mother)	1.3	1.6	3.2	-0.9	-1.4	-0.3	-0.4	-1.5	-1.8	1.6	1.1
Schizophrenia (2014)	1.3	2.8	9.6	1.3	0.9	3.1	1.3	1.2	1.4	-2.4	0.0
High blood pressure	1.3	3.8	11.9	-3.4	-1.2	-0.7	-1.5	-1.2	-2.0	2.2	2.0
Mouth/teeth dental problems: Loose teeth	1.3	1.5	5.8	2.4	0.5	1.1	1.6	0.6	0.8	-0.9	-0.7
Medication: Omeprazole	1.3	1.6	3.0	-0.1	1.5	0.6	-1.2	1.6	1.6	-0.6	-1.7
Ever taken oral contraceptive pill	1.3	1.5	2.9	0.3	1.5	0.5	-1.1	1.1	1.2	-1.7	-1.6
Ulcerative Colitis (UC)	1.2	2.3	2.9	-1.4	-1.7	-1.7	1.6	-1.2	-1.6	1.1	1.7
Mean Putamen Volume	1.2	1.3	4.8	-0.9	-1.2	-2.2	0.4	-1.1	-0.9	1.2	0.0
Rheumatoid Arthritis	1.2	1.6	3.4	-0.0	1.7	0.8	-1.1	1.5	1.8	-1.6	0.0
Hair/balding pattern: Pattern 2	1.2	1.5	2.8	1.7	1.1	0.4	-0.8	1.1	1.6	-1.5	-1.1
Financial difficulties in last 2 years	1.2	1.6	3.8	2.0	0.6	1.5	-1.1	0.9	1.1	-1.2	-1.2
Time employed in main current job	1.2	1.4	3.6	1.9	-0.9	-1.5	0.7	-1.1	-0.7	0.5	1.5
Qualifications: O levels/GCSEs or equivalent	1.2	1.9	3.8	0.9	-1.4	-1.9	1.8	-1.4	-1.3	-0.3	1.4
Reason for reducing amount of alcohol drunk: Health precaution	1.2	1.5	3.3	-0.3	1.6	-0.0	-1.0	1.5	1.8	-0.3	-1.6
Medication: Seretide 50 evohaler	1.2	1.3	2.2	0.6	1.1	1.1	-1.5	1.0	1.1	-1.3	-1.3
Friendships satisfaction	1.2	1.5	4.4	0.8	-0.7	-2.1	1.9	-0.9	-1.1	-0.2	0.7
Commuting to job workplace: Public transport	1.2	1.4	2.7	-0.3	-1.3	-1.0	0.7	-1.5	-1.3	1.0	1.6
Medication: Paracetamol	1.2	1.9	4.8	0.2	1.9	0.2	-0.4	2.2	1.6	-0.6	-1.8
Irritable Bowel Disease (IBD)	1.1	2.6	3.6	-1.9	-1.8	-1.2	1.5	-1.3	-1.8	1.6	1.7
Crohns Disease (2012)	1.1	1.7	4.0	-2.0	-1.4	-0.9	1.3	-1.2	-1.5	1.3	0.0
Systolic Blood Pressure	1.1	5.7	12.5	-3.3	-1.5	-1.0	-2.6	-1.5	-2.2	3.5	2.1
Medication: Co-codamol	1.1	1.3	4.3	0.4	0.9	2.1	0.5	0.8	0.8	-1.6	-0.9
Diabetes (father)	1.1	1.4	1.8	-1.2	-1.4	-1.1	-0.3	-1.2	-1.2	1.2	1.3
Pack years adult smoking proportion	1.1	1.6	2.7	1.6	-1.3	-1.4	1.5	-1.6	-0.7	0.5	1.2
Average weekly fortified wine intake	1.1	1.3	3.0	-1.0	-0.7	-1.2	-0.6	-1.4	-1.6	0.1	1.7
Hayfever/allergic rhinitis (self-reported)	1.1	1.4	3.0	-0.4	-1.3	-1.2	-0.3	-1.3	-1.7	0.8	1.7
Medication: Ramipril	1.1	1.5	4.1	-2.0	-1.2	-0.0	0.7	-1.2	-1.5	-0.6	1.2
Medication: Simvastatin	1.1	1.6	3.9	-1.5	-1.0	-2.0	1.0	-0.6	-1.2	1.3	1.0
Loud music exposure frequency	1.1	1.3	2.3	0.2	1.5	0.2	-0.8	0.9	1.5	-1.4	-1.4
Mouth/teeth dental problems: Bleeding gums	1.1	1.4	2.9	0.1	1.1	0.9	-1.1	1.4	1.7	-0.9	-1.5
Number of children fathered	1.1	1.3	3.3	0.7	1.3	-0.5	-0.5	1.5	1.8	-0.6	-1.2
Medication for cholesterol	1.1	1.7	7.3	1.9	0.3	1.2	2.7	0.2	0.7	-0.9	-0.4
Guilty feelings	1.1	1.6	3.8	-0.1	1.9	-0.0	-1.2	1.3	1.5	-1.4	-1.5
Vascular/heart problems diagnosed by doctor	1.1	3.0	9.1	3.0	1.2	0.9	1.1	1.1	1.8	-1.9	-1.8
Hand grip strength (left)	1.0	2.7	4.8	2.2	1.6	1.6	-0.2	1.6	1.3	-2.1	-1.8
Ever had hysterectomy (womb removed)	1.0	1.2	2.4	-1.5	1.1	-1.6	-1.3	0.8	0.5	0.1	-0.8
Stomach or abdominal pain in last month	1.0	1.3	2.6	-1.2	1.2	-0.3	-0.2	1.3	0.9	-1.5	-1.6
Falls in the last year	1.0	1.4	2.9	-0.3	1.6	0.4	-0.5	1.6	1.7	-1.2	-1.1
Serious illness, injury or assault of a close relative in last 2 years	1.0	1.1	2.0	-1.2	-0.7	-1.0	1.1	-0.9	-1.4	0.8	1.2
Length of working week for main job	1.0	1.2	1.9	-1.0	-1.3	-0.9	0.0	-1.4	-1.3	0.4	1.3
Had major operations	1.0	1.2	4.0	0.5	0.1	2.0	-0.5	0.2	0.9	-1.8	-0.9
Illnesses of father: Heart disease	1.0	1.4	2.6	1.5	1.1	1.6	-0.6	1.2	1.3	-0.8	-0.9
Pack years of smoking	1.0	1.4	2.7	1.6	-1.1	-1.4	1.5	-1.4	-0.4	0.6	1.1
Ovarian Cancer	0.9	1.1	2.8	0.9	-1.7	0.4	0.8	-1.4	-0.9	-0.3	1.3
Blood Red Count	0.9	9.0	16.5	-0.2	-3.6	-1.6	2.7	-3.9	-2.7	3.2	4.1
Relative age of first facial hair	0.9	1.9	8.5	-2.9	-0.6	-1.9	-0.2	-0.8	-1.0	0.6	0.7
Depression (self-reported)	0.9	1.1	2.5	-0.5	-1.3	-0.6	0.8	-1.4	-1.3	-0.0	1.6
Gout (self-reported)	0.9	1.3	4.9	2.2	0.6	0.5	1.5	0.4	0.7	-1.0	-0.9
Chronic bronchitis/emphysema (mother)	0.9	1.0	3.5	1.6	0.4	0.7	-0.6	0.4	0.6	-1.9	-0.6
Age at last live birth	0.9	1.3	2.6	-0.8	-1.6	-0.5	0.5	-1.4	-1.6	-0.7	1.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.9	1.1	2.4	-0.5	0.8	1.6	-0.8	0.8	1.2	-1.1	-1.2
Eye problems/disorders: Cataract	0.9	1.0	2.1	0.2	1.3	0.6	0.1	1.4	1.3	-0.6	-1.3
Illnesses of father: None of the above (group 1)	0.9	1.1	2.7	-0.1	1.7	0.7	-0.7	1.3	1.2	-0.6	-1.4
Eye problems/disorders: Glaucoma	0.9	1.1	6.8	-1.1	0.0	-2.6	-0.4	-0.1	-0.5	0.4	0.2
Medication: Blood pressure	0.9	1.8	3.6	-1.4	-0.9	-1.3	-1.9	-0.7	-1.3	1.4	1.3
Pain experienced in last month	0.9	1.4	4.1	-0.8	0.9	1.1	-2.0	1.1	1.2	-0.8	-1.3
Happiness	0.8	0.9	1.8	0.8	1.1	-0.5	0.6	1.0	0.9	-1.1	-1.3
Medication: Lansoprazole	0.8	0.9	1.4	-0.7	1.1	1.0	-1.1	1.0	1.1	-0.3	-1.2
Birth weight of first child	0.8	1.4	7.9	-2.8	0.7	0.1	-1.5	0.4	0.1	0.7	0.2
Ever highly irritable/argumentative for 2 days	0.8	1.0	4.4	-2.1	-0.3	-1.1	-0.9	-0.5	-0.4	0.9	0.4
Supplements: Vitamin C	0.8	0.9	2.2	-1.5	-0.8	-0.8	-1.2	-0.9	-0.7	0.6	0.8
Medication: Aspirin	0.8	1.1	1.8	-1.3	-1.0	-0.5	0.9	-0.7	-1.0	1.3	1.2
Hearing aid user	0.8	0.9	3.4	-0.9	0.8	0.3	-1.8	1.1	0.2	-0.5	-1.0
Irritability	0.8	1.3	3.0	0.6	1.1	1.7	-0.8	1.1	1.3	-0.5	-1.4
Ever depressed for a whole week	0.8	1.0	1.9	1.4	1.0	0.3	0.1	1.0	1.2	-1.1	-1.2
Breast Cancer	0.7	1.8	4.0	0.4	-1.9	-0.5	0.7	-1.9	-1.2	1.0	2.0
Allergy or Eczema	0.7	1.8	3.2	0.2	-1.4	-1.6	1.2	-1.7	-1.8	0.8	1.3
Respiratory disease	0.7	1.7	3.8	-0.1	1.8	0.6	-0.8	1.4	1.6	-0.9	-2.0
Medication for hormone replacement therapy	0.7	0.7	2.8	-1.1	0.2	-1.0	-1.7	0.0	-0.4	0.8	-0.3
Serious illness, injury or assault to yourself	0.7	0.9	1.7	0.2	1.0	0.8	-0.6	1.2	1.0	-1.0	-1.3
Diverticular disease/diverticulitis (self-reported)	0.7	0.8	1.9	-0.1	-1.0	-1.4	1.2	-0.7	-0.1	1.1	0.8
Mouth/teeth dental problems	0.7	1.1	2.5	-1.6	-0.6	-1.2	-0.9	-1.2	-1.1	0.4	1.0
Heart attack	0.7	0.9	3.9	-1.3	0.3	-2.0	-1.1	0.2	-0.4	0.0	-0.4
Noisy workplace	0.7	0.8	1.9	-1.4	1.0	-0.3	-0.8	0.8	0.5	-0.0	-1.3
Impedance of arm (left)	0.7	3.2	5.1	-1.6	-2.2	-2.0	1.7	-2.0	-1.8	1.4	1.6
Tense / ‘highly strung’	0.7	1.1	2.6	-0.3	1.4	1.1	-0.6	1.0	1.2	-0.5	-1.6
Medication: Amlodipine	0.7	1.0	3.7	-0.8	-0.4	-1.9	-0.8	-0.4	-0.4	1.5	0.6
Mouth/teeth dental problems: Mouth ulcers	0.7	1.1	3.8	2.0	-1.2	0.5	0.7	-0.7	-0.8	0.8	1.0
Fractured/broken bones in last 5 years	0.7	0.9	3.2	-1.8	-0.9	0.5	-0.9	-0.7	-0.7	0.3	1.0
Medication: Omeprazole (e.g. Zanprol)	0.7	0.8	1.7	-0.3	1.0	0.3	-1.3	0.9	1.2	-0.1	-1.2
Alcohol drinker status: Previous	0.7	0.8	1.5	-1.2	-0.9	0.5	-0.4	-1.0	-0.9	0.8	1.0
Bipolar Disorder (2018)	0.6	1.0	6.0	1.1	-0.6	0.0	2.4	0.1	-0.5	-0.0	0.0
Depression (Nagel 2018)	0.6	0.9	5.2	-0.1	0.8	0.5	-0.3	0.3	0.6	-2.3	-0.6
Fasting Glucose	0.6	0.7	1.5	-0.8	-0.5	-1.0	0.0	-0.7	-0.9	1.2	0.7
HbA1C	0.6	0.7	1.3	-0.5	-0.9	-0.4	-1.1	-0.8	-0.5	1.1	1.0
Frequency of depressed mood in last 2 weeks	0.6	0.9	3.9	0.2	0.6	0.1	-1.1	0.3	0.8	-2.0	-0.9
Current tobacco smoking	0.6	0.9	1.4	1.2	1.2	0.4	0.9	1.1	0.8	-0.7	-1.2
Fed-up feelings	0.6	1.1	3.0	-0.6	0.6	1.7	-1.5	0.6	0.6	-1.2	-0.7
Chronic bronchitis/emphysema (father)	0.6	0.7	1.4	-1.1	-0.8	-1.2	-0.1	-1.1	-0.9	0.3	0.5
Lung cancer (father)	0.6	0.7	2.4	-1.6	0.3	-0.2	-0.6	0.2	0.1	-1.5	-0.7
Illnesses of mother	0.6	0.7	1.5	0.8	0.9	-0.8	1.2	0.6	1.0	-0.1	-0.8
Neck or shoulder pain in last month	0.6	0.8	2.4	-0.5	-0.7	-0.6	0.5	-0.6	-1.0	1.6	1.2
Medication: Aspirin	0.6	0.8	1.5	-0.7	-0.9	-0.0	1.2	-0.7	-0.9	1.0	1.0
Knee pain experienced in last month	0.6	1.0	1.9	1.2	1.1	1.4	-0.1	0.9	0.8	-1.0	-0.8
Illnesses of siblings: Diabetes	0.6	0.7	1.5	1.2	0.3	1.2	-0.5	0.9	1.1	-0.2	-0.7
Number of self-reported non-cancer illnesses	0.6	1.0	4.6	-2.1	-0.6	-0.3	-0.6	-0.6	-0.8	1.0	0.9
Medication: Atorvastatin	0.6	0.8	2.4	-1.5	-1.0	0.2	0.0	-1.0	-0.9	0.0	0.9
Heart attack/myocardial infarction (self-reported)	0.6	0.7	2.8	-0.8	0.6	-1.7	-0.9	0.6	-0.0	-0.2	-0.8
Heart disease (siblings)	0.6	0.7	3.3	0.4	0.5	-0.7	-1.8	0.8	0.7	-0.0	-0.8
Bipolar Disorder or Schizophrenia	0.5	1.2	4.3	1.6	-0.3	1.4	2.1	0.4	0.3	-0.8	0.0
Neuroticism (2016)	0.5	0.7	1.6	0.3	1.2	0.6	0.2	1.1	0.7	-0.6	-1.2
Type 2 Diabetes (T2D) (2012)	0.5	0.5	4.4	0.0	0.0	0.0	0.0	0.0	-2.1	0.0	0.0
Blood Platelet Count	0.5	5.4	10.2	1.2	2.8	2.0	0.3	3.2	2.3	-2.5	-2.9
Ever used hormone-replacement therapy (HRT)	0.5	0.7	2.5	-0.5	0.6	-1.6	-1.0	0.7	0.3	0.6	-0.4
Systolic blood pressure, automated reading	0.5	1.5	4.8	-2.2	-0.1	0.5	-2.0	0.0	-0.3	1.6	0.8
Supplements: Zinc	0.5	0.5	1.0	-1.0	0.7	-0.0	-0.8	0.5	0.5	-1.0	-0.8
Age when periods started (menarche)	0.5	1.3	3.5	-1.9	-1.0	-0.3	-0.0	-1.2	-1.1	1.2	1.2
Tinnitus: Yes, but not now, but have in the past	0.5	0.6	2.7	0.8	0.5	-0.1	1.6	0.4	0.7	0.1	-0.2
Had menopause	0.5	0.6	2.3	0.3	-0.6	-0.5	1.5	-0.0	0.2	1.3	0.8
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	1.4	-0.1	0.8	-0.9	-0.6	0.5	0.7	-1.2	-0.8
Neuroticism score	0.5	1.1	2.7	-0.3	1.6	0.4	-0.7	1.2	1.1	-0.8	-1.4
Alcohol intake versus 10 years previously	0.5	0.7	1.7	-1.3	0.2	1.1	-1.0	0.9	0.3	-0.3	-0.7
Hair/balding pattern: Pattern 3	0.5	0.8	1.8	-1.3	-0.1	0.9	-1.2	-0.2	-0.6	1.1	0.5
Medication: Blood pressure	0.5	0.9	3.2	-1.8	-0.5	-0.9	0.1	-0.4	-1.0	1.1	0.9
Loneliness, isolation	0.5	0.6	1.3	-1.1	-1.1	-0.1	-0.7	-1.0	-0.8	-0.0	0.7
Average weekly champagne plus white wine intake	0.5	0.7	1.3	-0.9	-0.8	0.6	-0.4	-0.6	-1.1	0.7	1.1
Schizophrenia (2018)	0.4	0.8	3.1	1.1	0.1	1.8	0.7	0.5	0.6	-1.1	0.0
Alzheimer’s Disease (in father)	0.4	0.4	1.7	0.7	-0.0	0.9	1.3	0.3	-0.1	0.1	-0.3
Crohns Disease (2017)	0.4	0.9	2.4	-1.5	-1.0	0.1	0.6	-0.8	-1.2	1.1	0.8
Triglycerides	0.4	0.7	2.3	-1.5	0.4	0.8	-1.4	0.1	-0.1	-0.6	-0.4
Hypothyroidism (self reported)	0.4	0.9	1.6	1.3	1.1	0.6	0.7	1.1	0.9	-0.8	-1.1
Number of treatments/medications taken	0.4	0.8	2.9	-1.3	-0.3	-1.7	0.1	0.0	-0.4	1.1	0.5
Relative age voice broke	0.4	0.6	1.7	-1.3	0.7	-0.8	0.1	0.7	0.5	-0.5	-0.9
Heel bone mineral density (BMD) T-score, automated (left)	0.4	0.8	5.1	-2.3	0.4	0.1	-0.6	0.4	0.6	0.3	-0.4
Medication: Atenolol	0.4	0.5	1.8	-1.2	0.6	-0.7	-1.4	0.4	-0.1	-0.0	0.0
Pain all over the body in last month	0.4	0.4	0.9	1.0	-0.9	-0.6	-0.6	-0.9	-0.1	-0.2	0.5
Worrier / anxious feelings	0.4	0.8	2.6	-0.6	0.9	0.5	-1.6	0.7	0.8	-0.2	-0.9
Breastfed as a baby	0.4	0.5	1.1	-0.9	-0.9	-0.7	0.4	-0.7	0.1	0.7	1.0
Hair/balding pattern: Pattern 4	0.4	0.9	1.5	-0.1	-1.0	-1.1	0.9	-1.0	-0.8	1.0	1.2
Headache pain in last month	0.4	0.7	1.3	0.8	0.9	0.5	0.7	1.0	0.6	-1.0	-1.1
Wheeze or whistling in the chest in last year	0.4	0.8	2.9	-0.5	0.6	0.9	-1.7	0.9	0.5	-0.1	-0.7
Health satisfaction	0.4	0.5	0.8	0.9	0.7	0.1	0.2	0.8	0.9	-0.7	-0.7
Pulse rate, automated reading	0.4	1.3	1.9	-1.3	-0.8	-0.9	1.1	-1.2	-0.7	1.4	1.3
Leg pain on walking	0.4	0.5	1.5	-0.1	0.7	0.5	-0.1	0.8	0.7	-1.2	-0.9
Asthma (self-reported)	0.4	0.8	1.6	-0.6	1.0	0.9	-1.3	0.7	0.6	-0.4	-1.2
Alcohol drinker status: Never	0.4	0.5	1.5	1.2	0.3	0.0	1.2	0.6	0.2	0.6	0.0
Basal cell carcinoma (self-reported)	0.4	0.4	1.7	0.8	0.5	0.0	1.3	0.6	0.2	-0.7	-0.2
Impedance of whole body	0.4	1.8	2.9	-1.6	-1.6	-1.7	1.2	-1.4	-1.2	1.0	0.8
Arm predicted mass (left)	0.4	2.1	4.8	1.1	1.4	2.2	-1.2	1.1	1.6	-1.6	-0.8
Depressed Affect (Nagel 2018)	0.3	0.7	1.3	-0.6	-0.9	-0.3	0.4	-1.1	-1.1	-0.5	1.0
Neuroticism (Nagel 2018)	0.3	0.7	1.6	-0.8	1.1	0.7	-0.7	0.8	0.4	-1.2	-1.0
HDL Cholesterol	0.3	0.5	1.7	1.3	-0.1	0.2	1.3	0.3	0.5	-0.4	-0.3
Lung FEV1/FVC ratio	0.3	1.6	8.6	1.5	-0.5	-1.2	2.9	-0.1	-0.1	0.2	0.5
Angina	0.3	0.4	1.7	-0.1	-0.7	-0.3	0.8	-0.5	-1.3	0.2	0.6
Hand grip strength (right)	0.3	0.9	4.9	2.2	0.1	0.0	0.3	-0.1	-0.2	-1.4	-0.3
Taking other prescription medications	0.3	0.5	1.7	-1.3	0.2	-0.8	-0.8	0.3	-0.0	0.9	-0.0
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.4	1.1	-0.9	-0.7	-0.6	-0.1	-1.1	-0.6	-0.1	0.6
Allergy	0.3	0.6	1.4	0.5	0.6	1.0	0.3	0.8	1.2	-0.5	-0.9
Impedance of arm (right)	0.3	1.6	2.8	-0.8	-1.6	-1.7	1.6	-1.3	-1.1	0.7	0.9
Trunk fat-free mass	0.3	1.7	5.5	1.1	1.0	2.3	-1.0	0.7	1.4	-1.5	-0.5
Asthma	0.3	0.6	1.9	-0.6	0.8	0.8	-1.4	0.5	0.4	-0.1	-0.8
Prospective memory result	0.3	0.4	1.0	0.7	0.3	-0.2	-1.0	0.3	0.4	-0.9	-0.7
Trunk predicted mass	0.3	1.8	5.4	1.1	1.0	2.3	-1.0	0.8	1.5	-1.6	-0.5
Blood clot in the leg (DVT)	0.3	0.3	1.3	-0.2	0.2	-1.1	-1.2	0.0	-0.0	0.2	-0.2
Birth weight	0.3	0.7	2.0	0.4	-1.2	0.3	0.4	-0.9	-0.6	0.6	1.4
Worry too long after embarrassment	0.3	0.5	1.4	0.7	1.2	0.1	-0.7	0.8	0.9	-0.3	-0.6
Medication for pain relief, constipation, heartburn	0.3	0.6	1.5	-0.0	-0.8	-0.5	0.4	-1.2	-0.9	-0.6	0.9
Medication: Allopurinol	0.3	0.4	1.6	1.3	0.0	1.1	0.2	-0.2	0.2	-0.7	-0.2
Heart disease (mother)	0.3	0.3	1.1	-0.7	-0.6	0.5	-0.0	-0.5	-1.0	-0.1	0.4
Leg fat mass (right)	0.3	1.1	2.5	0.3	1.2	1.6	-0.1	1.1	1.6	-0.7	-0.9
Suffer from ‘nerves’	0.3	0.5	1.7	-1.3	0.9	-0.4	-0.0	0.5	-0.7	-0.0	-0.7
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.7	2.8	-1.7	-0.1	0.3	-0.9	-0.6	-0.8	-0.9	-0.1
Mood swings	0.3	0.6	1.3	-0.1	1.2	0.6	-0.5	0.7	1.1	-0.5	-1.0
Smoking status: Current	0.3	0.4	1.3	1.0	0.6	-0.0	1.1	0.5	0.3	-0.4	-0.6
Miserableness	0.3	0.5	1.5	-0.5	-0.7	-0.2	-0.2	-1.2	-1.1	-0.0	0.7
Wears glasses or contact lenses	0.3	0.3	0.8	-0.7	-0.2	0.9	-0.7	0.2	0.3	0.2	0.7
Medication: Lisinopril	0.3	0.5	1.8	-1.0	0.0	0.2	-0.4	0.1	-0.7	1.3	0.4
Arm fat-free mass (left)	0.3	1.6	3.6	0.8	1.3	1.9	-1.2	0.9	1.5	-1.3	-0.7
Risk taking	0.3	0.4	1.6	1.3	-0.3	0.1	0.8	-0.1	0.6	0.5	0.1
Myopia	0.3	0.4	1.2	-0.6	0.5	0.0	-1.1	0.3	0.8	-0.8	-0.6
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	1.7	-0.4	-0.1	-1.1	-1.3	-0.2	-0.2	0.3	-0.1
Alzheimer’s Disease (including proxy)	0.2	0.3	0.7	-0.0	-0.6	0.7	-0.1	-0.5	-0.8	0.7	0.1
LDL Cholesterol	0.2	0.3	0.9	-0.9	0.5	-0.6	0.7	0.3	0.3	-0.4	-0.3
Primary Biliary Cirrhosis	0.2	0.3	1.1	-1.0	0.5	-0.5	-0.3	0.3	0.2	0.5	-0.4
Diabetes (mother)	0.2	0.2	0.6	0.8	0.4	0.4	-0.0	0.5	0.2	-0.4	-0.6
Body mass index (BMI)	0.2	0.9	2.5	0.4	1.0	1.6	-0.2	1.1	1.1	-0.6	-0.7
Leg predicted mass (left)	0.2	0.8	3.5	0.6	0.6	1.9	-0.6	0.4	0.7	-1.1	-0.1
Number of incorrect matches in round	0.2	0.4	0.9	-0.4	0.4	-0.7	-0.1	0.8	0.9	0.7	-0.7
Nervous feelings	0.2	0.3	1.4	-1.2	-0.0	-0.9	0.3	-0.2	-0.5	-0.2	0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.4	1.5	-1.2	0.5	-0.7	-0.6	0.2	0.6	0.6	-0.2
Weight	0.2	0.8	3.8	0.2	0.7	1.9	-0.3	0.5	1.0	-0.7	-0.1
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.3	1.5	-1.2	-0.0	-0.0	0.1	-0.5	-0.4	-0.5	0.2
Hypothyroidism/myxoedema (self-reported)	0.2	0.3	0.6	0.5	0.6	-0.1	0.1	0.8	0.5	-0.6	-0.7
High blood pressure (siblings)	0.2	0.2	0.6	0.8	0.4	0.4	0.2	0.6	0.1	-0.7	-0.1
Leg fat percentage (right)	0.2	0.9	1.8	-0.1	1.1	1.2	0.3	1.1	1.3	-0.2	-1.0
Arm fat-free mass (right)	0.2	1.1	3.9	0.9	0.9	2.0	-0.9	0.5	1.2	-1.1	-0.2
Exposure to tobacco smoke outside home	0.2	0.3	0.9	-0.3	-0.0	0.5	-0.9	-0.5	0.1	0.7	0.5
Angina (self-reported)	0.2	0.2	1.0	0.2	-0.3	-0.1	0.8	-0.2	-1.0	-0.1	0.3
Medication: Ibuprofen	0.2	0.2	0.6	0.7	0.3	0.8	-0.2	0.4	0.1	-0.6	-0.5
Arm predicted mass (right)	0.2	1.0	3.1	0.8	0.9	1.8	-0.9	0.5	1.1	-1.0	-0.3
Alcohol intake frequency.	0.2	0.5	1.6	1.2	-0.1	0.6	1.1	0.4	-0.4	-0.7	-0.1
Overall health rating	0.2	0.4	1.1	0.8	0.3	1.0	0.5	0.5	0.4	-0.6	-0.6
Chest pain or discomfort	0.2	0.3	1.5	-0.6	0.2	0.1	-1.2	0.1	0.3	-0.3	-0.7
Illness, injury, bereavement, stress in last 2 years	0.2	0.3	1.0	-1.0	-0.0	0.6	-0.4	-0.2	0.2	0.7	0.3
Whole body fat-free mass	0.2	1.4	4.5	1.1	0.9	2.1	-0.8	0.6	1.2	-1.5	-0.3
Back pain experienced in last month	0.2	0.2	0.7	0.9	0.6	-0.0	0.8	0.4	-0.0	-0.2	-0.3
Whole body water mass	0.2	1.4	4.5	1.0	0.9	2.1	-0.9	0.6	1.2	-1.4	-0.3
Pain type(s) experienced in last month: Hip pain	0.2	0.3	1.9	-1.4	0.1	-0.2	0.4	0.1	-0.1	0.4	0.3
High cholesterol (Self-reported)	0.2	0.3	0.6	-0.7	-0.7	-0.8	0.5	-0.4	-0.5	0.2	0.3
Basal metabolic rate	0.2	1.3	4.8	0.8	0.9	2.2	-0.7	0.6	1.1	-1.4	-0.3
Leg fat percentage (left)	0.2	0.6	1.2	-0.1	0.9	1.0	0.3	1.0	1.1	-0.0	-0.6
Diastolic blood pressure, automated reading	0.2	0.5	1.4	-0.9	0.4	0.3	-1.1	0.3	0.5	1.2	0.2
Cholesterol lowering medication	0.2	0.3	1.2	-1.1	-0.5	-0.8	-0.4	-0.2	-0.2	0.4	0.4
Leg fat mass (left)	0.2	0.9	2.1	0.2	1.1	1.4	-0.0	1.0	1.4	-0.6	-0.7
Worry (Nagel 2018)	0.1	0.3	1.0	-1.0	0.3	0.4	0.0	0.2	-0.2	-0.7	-0.6
Body Mass Index (BMI) (2010)	0.1	0.1	0.5	-0.2	-0.0	-0.7	-0.4	-0.1	-0.1	-0.4	-0.1
Lupus	0.1	0.2	0.8	0.3	-0.1	-0.8	-0.9	0.1	0.1	0.2	0.0
Blood Eosinophil Count	0.1	0.8	3.7	-0.1	0.1	-1.4	1.9	0.2	-0.1	0.6	-0.2
Blood White Count	0.1	0.6	1.9	-1.4	-0.2	-0.3	0.6	-0.4	-1.0	1.1	0.5
Heel T-Score	0.1	1.0	3.5	-1.2	-0.3	-1.6	-0.4	-0.1	0.4	1.9	-0.6
BMI	0.1	0.3	1.1	0.2	0.3	1.1	-0.5	0.3	0.5	-0.7	0.3
Height	0.1	2.7	7.2	-0.9	-2.2	1.2	0.1	-2.7	-1.0	1.2	2.2
Waist Hip Ratio (WHR)	0.1	0.6	3.0	-1.7	-0.7	0.2	0.1	-0.7	-0.7	0.4	0.5
Neuroticism	0.1	0.3	1.7	-1.3	0.6	0.0	-0.2	0.3	-0.2	-0.1	-0.5
Hair Pigment	0.1	2.3	5.4	1.7	1.2	2.3	0.0	1.8	1.2	-0.5	-2.0
Tanning	0.1	1.5	4.8	-0.2	1.0	2.2	-1.7	0.9	1.4	0.1	-0.5
Other serious medical condition/disability diagnosed by doctor	0.1	0.1	0.2	-0.2	-0.4	-0.4	-0.1	-0.5	-0.2	-0.3	0.4
Impedance of leg (right)	0.1	0.4	1.8	-0.6	0.3	0.0	-0.1	0.4	0.9	-0.2	-1.4
Leg fat-free mass (left)	0.1	0.7	3.2	0.4	0.5	1.8	-0.6	0.2	0.6	-1.0	0.1
Medication: Levothyroxine sodium	0.1	0.1	0.5	0.7	0.2	0.1	0.6	0.3	0.2	0.1	-0.1
High blood pressure (mother)	0.1	0.1	0.3	0.3	-0.5	0.3	-0.1	-0.2	-0.4	-0.2	0.4
Trunk fat mass	0.1	0.3	1.2	-0.3	0.5	1.1	0.2	0.4	0.9	-0.2	-0.0
Waist circumference	0.1	0.3	0.8	-0.9	-0.2	0.9	0.3	-0.2	-0.0	0.5	0.5
Arm fat percentage (right)	0.1	0.3	1.0	0.1	0.1	0.9	1.0	0.3	0.5	-0.4	-0.0
Hip circumference	0.1	0.3	1.3	-0.3	-0.2	1.1	0.6	-0.1	-0.2	0.4	0.7
Pulse rate	0.1	0.1	0.3	-0.1	0.4	0.5	0.5	0.2	0.5	0.4	0.1
Mouth/teeth dental problems: Dentures	0.1	0.2	0.4	-0.1	0.3	0.6	-0.5	0.4	0.3	0.5	-0.2
Medication: Ibuprofen (e.g. Nurofen)	0.1	0.2	0.6	0.8	0.1	0.7	-0.5	0.3	0.2	-0.2	-0.3
Arm fat mass (right)	0.1	0.4	1.8	0.1	0.4	1.4	0.4	0.5	0.8	-0.8	-0.1
Standing height	0.1	0.7	1.9	-0.8	-0.8	0.8	-0.4	-1.2	-0.2	0.0	1.4
Peak expiratory flow (PEF)	0.1	0.1	0.3	0.0	-0.1	0.2	-0.4	-0.3	-0.5	-0.5	0.5
Body fat percentage	0.1	0.3	0.7	-0.3	0.5	0.8	0.6	0.5	0.8	-0.1	-0.2
Comparative body size at age 10	0.1	0.3	0.8	0.6	-0.2	0.6	-0.9	-0.2	-0.4	-0.5	0.6
Whole body fat mass	0.1	0.4	1.8	-0.1	0.5	1.3	0.3	0.5	0.9	-0.3	-0.1
Comparative height size at age 10	0.1	0.7	1.3	0.9	0.6	1.1	1.1	0.4	1.1	-0.8	-0.1
Leg fat-free mass (right)	0.1	0.6	2.3	0.7	0.4	1.5	-0.5	0.1	0.4	-1.1	0.3
Arm fat percentage (left)	0.1	0.2	1.1	-0.1	-0.1	0.6	1.0	0.1	0.3	-0.1	0.2
Long-standing illness, disability or infirmity	0.1	0.2	0.7	-0.3	0.2	0.0	-0.4	0.4	-0.1	-0.8	-0.1
Leg predicted mass (right)	0.1	0.5	2.1	0.7	0.3	1.4	-0.4	0.1	0.4	-1.0	0.4
Arm fat mass (left)	0.1	0.3	1.1	0.0	0.4	1.1	0.4	0.4	0.7	-0.4	-0.0
Mother’s age at death	0.1	0.1	0.2	0.3	0.3	0.4	0.2	-0.0	0.4	-0.3	0.1
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.6	-0.0	0.0
Chronotype (morning person)	0.0	0.1	0.3	0.3	0.1	0.0	0.5	0.2	-0.2	-0.5	-0.3
Trunk fat percentage	0.0	0.2	0.4	-0.6	0.2	0.5	0.6	0.2	0.5	0.2	0.1
Townsend deprivation index at recruitment	0.0	0.1	0.3	-0.2	0.0	0.3	0.1	0.0	0.0	-0.6	-0.2
Sitting height	0.0	0.3	0.7	-0.8	-0.0	0.7	-0.2	-0.6	0.5	-0.3	0.5
Impedance of leg (left)	0.0	0.2	0.7	-0.4	0.0	-0.6	0.3	0.1	0.5	0.0	-0.8

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