TWAS hub - CYP2D8P1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.131	0.0420	2.8e-06	0.019	NA	0.065	NA	0.058	9.6e-03	NA	4.8e-06	NA	1.6e-05
2	GTEx	Adipose Visceral Omentum	0.178	0.0500	1.8e-07	0.176	NA	0.151	NA	0.174	1.9e-09	NA	3.2e-08	NA	2.2e-09
3	GTEx	Artery Aorta	0.246	0.0640	1.9e-06	0.072	NA	0.084	NA	0.052	8.6e-05	NA	2.2e-05	NA	7.3e-04
4	GTEx	Artery Coronary	0.135	0.0620	8.6e-03	0.014	NA	0.038	NA	0.044	1.0e-01	NA	2.0e-02	NA	1.3e-02
5	GTEx	Brain Caudate basal ganglia	0.143	0.0680	9.4e-03	0.002	NA	-0.010	NA	-0.010	2.7e-01	NA	7.9e-01	NA	7.8e-01
6	GTEx	Brain Cerebellar Hemisphere	0.233	0.0800	7.2e-04	0.045	NA	0.042	NA	0.034	2.7e-02	NA	3.2e-02	NA	4.7e-02
7	GTEx	Brain Cerebellum	0.258	0.0700	1.9e-06	0.224	NA	0.239	NA	0.249	3.0e-07	NA	1.1e-07	NA	5.7e-08
8	GTEx	Breast Mammary Tissue	0.187	0.0520	3.0e-06	0.060	NA	0.076	NA	0.090	5.0e-04	NA	9.7e-05	NA	2.3e-05
9	GTEx	Breast Mammary Tissue (Male)	0.293	0.1067	5.1e-03	-0.004	NA	0.021	NA	0.023	4.2e-01	NA	1.0e-01	NA	9.7e-02
10	GTEx	Breast Mammary Tissue (Female)	0.239	0.0865	5.2e-04	0.034	NA	0.064	NA	0.051	3.6e-02	NA	5.6e-03	NA	1.2e-02
11	GTEx	Colon Transverse	0.150	0.0470	6.8e-06	0.093	NA	0.117	NA	0.128	3.6e-05	NA	3.4e-06	NA	1.1e-06
12	GTEx	Esophagus Mucosa	0.176	0.0440	3.2e-09	0.168	NA	0.169	NA	0.184	2.2e-11	NA	2.0e-11	NA	2.3e-12
13	GTEx	Esophagus Muscularis	0.124	0.0510	3.9e-04	0.032	NA	0.038	NA	0.049	4.9e-03	NA	2.2e-03	NA	6.3e-04
14	GTEx	Liver	0.454	0.1220	3.6e-04	0.145	NA	0.210	NA	0.241	7.5e-05	NA	1.6e-06	NA	2.3e-07
15	GTEx	Lung	0.165	0.0466	6.3e-08	0.081	NA	0.084	NA	0.074	9.3e-07	NA	5.3e-07	NA	2.8e-06
16	GTEx	Nerve Tibial	0.149	0.0447	6.8e-07	0.091	NA	0.102	NA	0.109	5.1e-07	NA	1.2e-07	NA	3.8e-08
17	GTEx	Ovary	0.395	0.1110	3.1e-05	0.192	NA	0.240	NA	0.249	1.8e-05	NA	1.3e-06	NA	8.2e-07
18	GTEx	Pituitary	0.355	0.1240	2.6e-04	0.031	NA	0.075	NA	0.075	5.8e-02	NA	6.2e-03	NA	6.1e-03
19	GTEx	Prostate	0.211	0.0730	7.4e-04	0.074	NA	0.105	NA	0.114	6.3e-03	NA	1.3e-03	NA	8.5e-04
20	GTEx	Skin Not Sun Exposed Suprapubic	0.202	0.0500	5.7e-09	0.134	NA	0.181	NA	0.182	8.3e-08	NA	3.3e-10	NA	3.0e-10
21	GTEx	Skin Sun Exposed Lower leg	0.144	0.0390	3.8e-09	0.041	NA	0.067	NA	0.091	2.5e-04	NA	3.2e-06	NA	5.5e-08
22	GTEx	Small Intestine Terminal Ileum	0.364	0.1340	2.6e-04	0.141	NA	0.203	NA	0.313	4.8e-04	NA	2.7e-05	NA	8.8e-08
23	GTEx	Spleen	0.203	0.0880	5.2e-03	0.068	NA	0.037	NA	0.114	8.2e-03	NA	4.1e-02	NA	7.7e-04
24	GTEx	Thyroid	0.280	0.0610	5.6e-17	0.210	NA	0.224	NA	0.249	5.6e-16	NA	4.4e-17	NA	4.5e-19
25	GTEx	Whole Blood	0.045	0.0220	7.0e-03	0.000	NA	0.008	NA	0.003	3.4e-01	NA	5.8e-02	NA	1.5e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25
Mouth/teeth dental problems: Loose teeth	7.1	8.4	13.1	2.8	2.7	2.9	3.6	2.4	1.3	2.3	3.1	2.9	2.4	3.4	3.0	2.9	2.1	2.6	2.9	2.7	3.3	3.1	3.1	3.4	3.2	3.2	3.1	3.0
Alzheimer’s Disease (in mother)	5.9	6.9	12.3	2.1	2.7	2.4	2.0	1.8	2.1	2.9	2.8	2.2	1.8	3.0	3.5	3.3	1.3	3.2	3.3	2.4	2.9	2.8	2.7	2.7	3.0	3.0	2.6	2.0
Schizophrenia (2018)	4.7	9.8	20.5	2.7	1.6	3.7	4.3	4.5	-1.4	-0.1	2.9	1.5	4.4	3.0	3.0	3.4	2.8	1.9	1.9	3.7	4.4	2.6	2.5	3.6	3.5	4.2	3.9	1.2
Chronotype (morning person)	4.5	10.3	24.0	-3.0	-4.4	-3.6	-3.0	0.5	-3.4	-4.2	-2.6	-4.9	0.6	-3.1	-3.6	-3.6	0.1	-3.3	-4.3	-1.1	-2.4	-3.9	-4.0	-3.2	-2.1	-2.4	-1.7	-4.6
Ever used hormone-replacement therapy (HRT)	4.5	5.8	8.4	-1.9	-2.8	-1.9	-1.5	-2.5	-2.6	-2.8	-2.9	-2.6	-2.2	-2.4	-2.5	-2.4	-2.2	-1.8	-2.9	-2.2	-2.5	-2.5	-2.6	-2.6	-2.9	-2.2	-2.4	-1.6
Pulse wave Arterial Stiffness index	4.1	4.8	8.9	-2.0	-2.7	-1.3	-0.7	-1.3	-3.0	-3.0	-2.7	-2.4	-1.5	-2.8	-1.7	-1.4	-2.0	-2.7	-2.5	-1.9	-2.0	-2.6	-2.3	-2.4	-1.6	-1.3	-2.3	-2.5
Pulse wave reflection index	4.0	4.9	7.0	-1.9	-2.6	-2.0	-1.5	-1.5	-2.4	-2.5	-2.5	-2.5	-1.6	-2.6	-2.3	-2.2	-1.7	-2.6	-2.6	-1.9	-2.2	-2.6	-2.5	-2.5	-1.9	-2.0	-2.4	-2.1
Pulse wave peak to peak time	4.0	4.8	8.4	2.0	2.6	1.4	0.9	1.4	2.9	2.9	2.7	2.4	1.6	2.7	1.7	1.4	2.0	2.7	2.5	1.9	2.1	2.6	2.3	2.4	1.7	1.3	2.3	2.4
Chronic bronchitis/emphysema (father)	3.8	4.4	9.8	-2.0	-2.8	-1.6	-0.7	-1.1	-3.1	-3.1	-2.3	-2.7	-1.2	-1.9	-2.5	-2.5	-1.0	-2.1	-2.8	-1.9	-1.5	-2.5	-2.3	-1.9	-1.4	-1.7	-2.0	-1.0
Chronic bronchitis/emphysema (mother)	3.8	4.4	6.4	-2.2	-2.0	-2.3	-1.5	-1.9	-1.6	-1.8	-2.3	-2.1	-1.8	-2.1	-2.3	-2.2	-1.8	-2.5	-2.1	-2.1	-2.2	-2.0	-2.1	-2.2	-2.3	-2.2	-2.0	-2.4
Schizophrenia (2014)	3.7	8.1	19.3	2.3	1.2	3.5	4.4	4.0	-2.1	-0.6	2.4	1.1	4.0	2.7	2.5	2.9	2.2	1.6	1.4	3.3	4.1	2.2	2.3	3.4	3.0	4.1	3.4	1.7
Diabetes (mother)	3.6	4.5	8.4	2.1	2.1	1.8	2.3	2.5	-0.3	1.4	2.2	1.8	2.2	2.2	2.4	2.5	-0.0	1.4	2.3	2.4	2.9	2.3	2.4	2.6	2.0	2.7	2.5	1.2
Number of incorrect matches in round	3.3	5.4	12.2	-2.4	-3.1	-3.5	-2.1	-0.3	-2.4	-2.9	-2.1	-3.4	-0.4	-1.8	-2.9	-3.0	-0.3	-1.8	-3.1	-1.5	-1.8	-2.8	-2.9	-2.1	-1.6	-2.0	-1.3	-2.2
Blood clot in the leg (DVT)	3.3	4.3	9.9	-3.1	-2.3	-1.6	-1.0	-1.4	-2.0	-2.1	-2.6	-2.2	-1.8	-1.9	-1.7	-1.5	-3.0	-2.6	-2.2	-1.8	-2.0	-2.2	-2.2	-2.1	-2.0	-1.4	-2.1	-1.4
Commuting to job workplace: Public transport	3.2	3.8	7.4	2.1	2.6	1.2	1.1	1.3	2.7	2.4	2.1	2.6	1.4	2.0	2.2	2.3	0.3	1.9	2.4	1.4	1.8	2.3	2.2	2.0	1.5	1.5	1.9	1.7
Fractured/broken bones in last 5 years	3.2	4.2	6.0	-1.3	-2.3	-1.9	-2.0	-2.0	-0.8	-2.0	-2.4	-2.3	-1.7	-2.2	-1.9	-2.0	-2.1	-1.7	-2.2	-2.3	-2.1	-2.1	-2.3	-2.5	-2.3	-2.1	-2.2	-1.5
Number of treatments/medications taken	2.9	5.3	10.0	-2.3	-2.7	-1.9	-1.9	-1.6	-3.2	-2.7	-2.4	-2.6	-1.3	-2.0	-2.4	-2.2	-2.6	-2.6	-2.8	-2.0	-2.0	-2.5	-2.6	-2.2	-1.9	-1.8	-2.2	-2.0
Nervous feelings	2.9	5.4	12.9	2.3	2.3	1.9	1.5	1.9	2.1	2.0	2.6	2.0	2.4	2.3	2.4	2.5	2.2	2.9	2.4	2.2	2.6	2.3	2.4	2.3	3.6	2.2	2.4	1.4
Medication: Cholesterol lowering	2.9	4.6	10.4	-2.2	-2.5	-1.5	-1.4	-1.0	-3.2	-2.4	-2.1	-2.9	-1.1	-1.7	-2.5	-2.5	-0.9	-2.6	-2.6	-2.1	-1.8	-2.2	-2.3	-2.0	-1.5	-1.8	-1.7	-2.7
Loud music exposure frequency	2.9	3.2	8.5	1.1	1.8	0.6	1.9	1.2	2.0	1.9	2.2	1.3	1.9	2.2	1.1	0.8	1.5	2.8	1.5	2.2	1.5	1.8	1.9	1.9	1.7	1.2	1.8	2.9
Number of self-reported non-cancer illnesses	2.9	5.1	10.5	-2.8	-2.8	-2.6	-2.0	-0.8	-3.1	-2.6	-2.2	-3.2	-0.9	-1.8	-2.1	-2.1	-2.5	-2.1	-2.6	-1.3	-1.5	-2.5	-2.7	-2.2	-1.3	-1.6	-1.7	-3.0
Body Mass Index (BMI) (2010)	2.8	3.9	8.7	-2.3	-2.9	-1.2	-1.3	-0.0	-1.8	-3.0	-1.6	-2.9	0.2	-2.0	-2.1	-1.9	-2.4	-1.3	-2.6	-0.9	-1.4	-2.6	-2.5	-2.0	-2.4	-1.3	-1.1	-1.3
Ever smoked	2.8	4.9	11.9	2.9	3.2	2.3	1.3	-1.3	3.1	3.5	1.5	3.2	-0.9	2.2	2.0	1.7	1.2	2.7	2.8	-0.1	0.9	2.8	2.8	1.8	1.7	0.9	0.8	2.9
Myopia	2.8	4.1	13.7	2.2	2.7	2.2	0.7	0.1	3.7	3.2	1.9	2.6	0.2	2.1	1.8	1.3	1.1	2.1	2.5	0.0	1.1	2.4	2.3	1.7	1.2	0.8	1.1	3.5
Supplements: Calcium	2.8	3.1	6.8	-1.4	-2.0	-2.6	-1.2	-0.4	-1.8	-1.9	-1.3	-2.0	-0.8	-1.7	-1.9	-1.8	-1.3	-2.1	-2.0	-1.4	-1.3	-2.0	-2.0	-1.8	-1.5	-1.8	-1.2	-2.6
Average weekly spirits intake	2.7	3.3	10.7	-1.3	-0.8	-0.2	-2.6	-2.9	-1.2	-0.3	-1.9	-0.6	-3.3	-2.1	-1.5	-1.5	-1.6	-1.7	-0.8	-2.6	-1.8	-1.4	-1.5	-1.9	-1.8	-2.3	-2.6	-1.3
Eye problems/disorders: Diabetes related eye disease	2.7	3.0	6.4	-2.3	-2.2	-2.5	-0.9	-0.0	-1.7	-2.3	-1.2	-2.3	-0.4	-1.9	-1.6	-1.5	-1.9	-1.7	-1.9	-0.7	-1.0	-2.1	-2.0	-1.8	-1.9	-1.4	-1.1	-2.1
Birth weight of first child	2.7	4.9	12.9	-3.6	-3.0	-1.6	-1.2	0.7	-2.9	-3.5	-1.8	-2.4	0.2	-2.2	-2.3	-1.8	-1.5	-3.3	-2.9	-0.8	-1.2	-2.6	-2.6	-1.8	-2.0	-1.2	-1.2	-2.4
Friendships satisfaction	2.7	3.3	10.4	-0.5	0.7	1.6	3.2	2.7	-1.8	0.0	1.6	0.8	2.9	1.8	1.5	1.7	0.4	0.2	0.9	2.5	2.6	1.3	1.5	2.1	2.4	2.5	2.3	0.3
Bipolar Disorder or Schizophrenia	2.6	6.2	16.0	1.3	0.7	2.6	4.0	3.9	-1.7	-1.1	2.0	0.4	4.0	2.3	2.1	2.6	1.8	1.3	0.8	3.4	3.5	1.6	1.7	2.8	2.6	3.6	3.2	1.5
Qualifications: A levels/AS levels or equivalent	2.6	5.7	20.9	1.5	3.2	1.7	1.1	1.3	4.6	3.8	2.5	3.5	1.3	1.9	2.4	2.3	1.1	2.5	3.1	1.5	1.4	2.8	2.8	2.1	1.4	1.5	1.7	2.5
Smoking Status	2.4	5.7	27.6	2.3	3.1	2.9	1.7	-2.6	2.6	2.9	0.6	3.0	-1.6	2.0	2.2	2.3	0.2	2.5	2.9	-0.2	1.0	2.9	2.8	1.8	1.6	1.4	0.3	5.3
Allergy	2.4	5.4	10.2	3.0	3.0	3.2	2.2	0.4	1.2	2.7	2.0	2.7	0.8	2.3	2.4	2.3	2.2	2.0	2.8	1.6	2.0	2.9	3.0	2.5	1.7	2.1	1.8	2.6
Deep venous thrombosis (DVT) (self-reported)	2.4	3.0	8.3	-2.9	-2.0	-1.2	-0.5	-1.0	-2.0	-2.0	-2.2	-2.0	-1.3	-1.5	-1.3	-1.1	-2.8	-2.3	-1.9	-1.3	-1.6	-1.8	-1.9	-1.7	-1.6	-0.9	-1.7	-0.9
Alzheimer’s Disease (including proxy)	2.2	3.2	9.0	1.8	1.7	3.0	0.9	1.3	0.1	1.3	1.6	1.4	0.9	2.0	2.6	2.5	0.5	1.6	2.3	1.3	2.4	1.8	1.5	1.9	2.4	2.3	1.4	1.1
Past tobacco smoking	2.2	4.0	9.4	-2.3	-2.9	-2.5	-1.2	1.3	-2.5	-3.1	-1.1	-2.8	0.8	-2.0	-2.0	-1.8	-1.2	-2.1	-2.7	0.2	-0.8	-2.6	-2.5	-1.7	-2.0	-1.1	-0.7	-2.3
Intelligence (Savage-Jansen 2018)	2.1	6.4	23.7	1.2	3.8	2.2	1.3	0.1	4.9	4.5	2.7	4.9	-0.3	1.3	2.5	2.5	-0.8	2.1	3.7	1.0	1.0	3.0	3.0	1.5	-0.6	0.5	1.2	2.3
Age when periods started (menarche)	2.1	5.1	9.1	2.2	2.5	2.4	2.3	0.7	2.4	2.4	1.7	2.4	1.1	2.5	3.0	2.9	0.8	2.2	2.5	2.0	1.8	2.5	2.6	2.3	2.0	2.7	1.7	3.0
Noisy workplace	2.1	2.6	7.7	-2.3	-1.8	-1.6	-0.2	-1.3	-2.8	-2.0	-1.9	-2.5	-0.8	-0.7	-1.6	-1.6	-2.2	-1.5	-2.1	-0.7	-1.6	-1.5	-1.4	-1.2	-1.0	-0.7	-1.5	-0.2
Mouth/teeth dental problems: Mouth ulcers	2.1	3.3	5.3	1.1	2.0	1.3	1.3	1.0	2.0	2.2	2.3	1.9	1.5	2.2	1.9	1.7	0.6	2.3	2.1	2.1	1.8	2.2	1.9	2.0	1.7	1.6	1.8	1.7
Alzheimer’s Disease (in father)	2.0	2.1	8.6	2.2	1.5	2.9	0.5	0.8	-0.1	0.8	1.0	1.4	0.1	1.3	2.0	2.1	0.3	0.7	1.8	0.9	2.0	1.5	1.2	1.5	1.7	1.6	1.3	1.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.0	2.4	5.8	2.3	1.4	1.6	1.4	1.3	0.6	0.9	1.4	1.2	1.6	1.7	1.2	1.1	2.4	1.4	1.2	1.4	1.7	1.4	1.6	1.9	2.2	1.6	1.5	1.7
Schizophrenia vs Biploar Disorder	1.9	2.5	8.3	2.9	0.9	2.0	1.1	1.8	0.0	0.5	1.4	0.8	1.6	1.6	1.5	1.6	2.6	1.3	1.0	1.1	2.0	1.2	1.1	1.5	2.3	1.7	1.7	0.2
HbA1C	1.9	2.1	5.3	-0.8	-1.1	-1.8	-1.5	-0.6	-2.3	-1.6	-1.3	-1.5	-1.3	-1.6	-1.3	-1.4	-1.9	-2.0	-1.4	-0.6	-0.6	-1.0	-1.2	-1.3	-1.6	-1.3	-1.4	-2.1
Blood Eosinophil Count	1.9	14.9	31.8	2.8	2.5	2.6	5.2	5.4	4.0	2.2	4.4	1.9	5.6	3.8	4.0	3.7	3.2	4.6	2.8	4.7	4.1	3.1	3.5	3.8	3.7	4.4	4.9	1.8
Type 2 Diabetes (T2D) (2018)	1.9	3.6	6.5	-2.2	-2.1	-2.0	-1.7	-0.6	-2.3	-2.2	-2.0	-2.5	-1.2	-2.1	-2.2	-2.3	0.2	-1.8	-2.0	-1.7	-1.2	-2.1	-2.1	-1.9	-1.0	-1.9	-1.6	-2.1
Medication: Co-codamol	1.9	2.2	4.1	0.7	1.6	1.4	1.4	1.9	0.8	1.4	2.0	1.6	1.0	1.6	1.4	1.4	1.0	1.6	1.8	1.3	1.8	1.6	1.8	1.6	1.3	1.2	1.8	1.2
Severe depression (siblings)	1.9	2.1	7.4	1.1	1.0	1.2	2.7	1.6	0.5	0.5	1.4	0.7	1.8	1.7	1.6	1.7	0.8	1.1	1.0	1.7	1.5	1.4	1.6	1.6	1.6	2.0	1.5	0.9
Taking other prescription medications	1.9	2.9	5.2	-1.6	-2.0	-1.7	-1.6	-1.2	-1.3	-1.8	-1.9	-2.3	-1.1	-1.7	-1.5	-1.4	-1.8	-1.3	-1.9	-1.9	-1.6	-1.9	-2.0	-2.0	-1.4	-1.5	-1.7	-2.1
Birth weight	1.9	4.2	8.8	-2.6	-2.6	-1.9	-1.2	0.3	-2.9	-2.9	-1.5	-2.3	-0.7	-1.8	-2.0	-1.8	-3.0	-2.4	-2.4	-0.9	-1.0	-2.2	-2.4	-1.8	-2.9	-1.5	-0.9	-2.1
Heart disease (mother)	1.9	2.4	8.2	-2.1	-2.0	-2.2	-0.4	0.9	-1.8	-2.0	-1.0	-1.9	0.5	-1.5	-1.6	-1.3	-0.3	-2.1	-1.9	-0.5	-0.9	-1.7	-1.6	-1.3	-0.6	-0.8	-0.5	-2.9
Mother’s age at death	1.9	2.4	5.9	-1.8	-0.5	-1.6	-2.1	-2.4	0.4	-0.1	-1.5	0.3	-2.0	-1.9	-1.4	-1.1	-2.2	-1.3	-0.8	-1.7	-2.2	-1.1	-1.0	-1.7	-1.7	-1.9	-2.0	0.3
Blood White Count	1.8	13.1	24.9	2.6	2.0	3.5	4.8	4.2	0.6	0.7	3.2	1.5	4.7	3.7	3.9	4.1	4.8	3.1	2.4	4.3	4.0	3.1	3.1	3.7	5.0	4.9	4.3	2.9
Had menopause	1.8	2.2	6.2	-0.6	-1.0	-1.2	-2.5	-1.7	-0.7	-0.6	-1.6	-0.7	-2.1	-2.1	-1.2	-1.3	-0.8	-1.3	-0.7	-2.1	-1.5	-1.4	-1.5	-1.9	-1.8	-1.9	-1.8	-0.9
Headache pain in last month	1.8	3.1	13.9	-2.8	-2.1	-1.2	0.4	-0.8	-3.7	-2.8	-1.5	-1.7	-0.9	-1.5	-1.0	-0.5	-2.8	-1.9	-1.8	-0.3	-0.6	-1.8	-1.6	-1.3	-1.0	-0.3	-1.0	-2.6
Qualifications: College or University degree	1.8	5.7	23.6	2.1	3.3	1.8	1.1	0.6	4.9	3.9	2.7	4.4	0.3	1.2	2.4	2.7	0.3	1.6	3.4	0.9	1.2	2.7	2.8	1.6	1.0	0.9	1.3	2.1
Pulse rate, automated reading	1.8	5.9	11.2	1.0	2.4	1.5	3.0	2.5	1.1	1.9	2.9	2.1	2.7	2.7	2.7	2.6	0.5	3.3	2.5	3.2	2.6	2.6	2.7	2.8	1.5	2.9	2.9	1.4
Osteoporosis (self-reported)	1.8	2.2	7.9	-1.0	-2.3	-1.1	-0.5	-0.1	-2.0	-2.8	-1.6	-2.2	0.1	-1.3	-1.2	-0.9	-0.4	-1.2	-2.3	-0.4	-1.3	-2.0	-2.0	-1.5	-0.7	-0.6	-0.8	-1.7
Pack years adult smoking proportion	1.7	2.6	4.5	2.1	1.5	2.1	2.1	0.3	0.3	1.2	1.4	1.5	0.6	1.7	2.0	2.0	-0.0	1.7	1.8	1.7	1.8	1.7	1.7	1.8	1.1	2.0	1.5	2.0
Average weekly fortified wine intake	1.7	2.0	6.3	1.3	2.0	1.4	0.1	0.4	2.5	2.3	1.3	1.8	0.2	1.0	1.8	1.7	1.7	1.5	2.2	0.4	0.8	1.6	1.5	0.9	1.2	0.8	1.0	0.2
Stomach or abdominal pain in last month	1.7	2.2	6.3	1.0	0.4	1.8	2.5	1.9	0.1	-0.2	1.3	0.4	2.2	1.7	1.2	1.3	0.7	1.2	0.4	1.9	1.7	0.9	1.2	1.7	1.3	2.1	1.8	1.9
Financial difficulties in last 2 years	1.7	2.2	3.2	0.5	1.5	1.4	1.8	1.1	1.6	1.2	1.7	1.4	1.4	1.2	1.6	1.6	0.6	1.7	1.8	1.7	1.8	1.3	1.6	1.6	1.6	1.6	1.6	1.7
Alcohol intake frequency.	1.7	3.8	8.5	-1.9	-2.7	-2.6	-1.7	0.1	-2.5	-2.7	-1.4	-2.8	0.3	-1.9	-2.1	-2.2	0.3	-1.3	-2.5	-0.2	-1.1	-2.7	-2.6	-1.8	-1.0	-1.4	-0.8	-2.9
Smoking status: Current	1.7	2.7	16.5	2.0	1.9	2.2	1.3	-1.1	1.4	1.6	0.7	1.7	-0.3	1.3	1.4	1.6	0.0	2.1	1.8	0.6	1.1	2.0	1.9	1.4	0.8	1.2	0.6	4.1
Crohns Disease (2012)	1.6	2.5	5.8	-2.1	-2.4	-1.3	-0.5	-0.6	-1.6	-2.4	-1.4	-2.1	-0.4	-1.7	-1.8	-1.4	-1.1	-1.0	-2.2	-0.7	-1.5	-2.0	-1.9	-1.8	-1.6	-1.2	-1.4	-1.3
Hand grip strength (left)	1.6	4.2	16.7	-1.9	-3.2	-0.5	0.3	0.7	-3.5	-4.1	-2.0	-2.9	0.4	-1.6	-2.1	-1.8	-1.2	-2.6	-3.1	-0.8	-0.8	-2.4	-2.4	-1.4	-2.2	-0.5	-0.9	-1.0
Townsend deprivation index at recruitment	1.6	2.2	5.8	1.2	2.0	1.3	1.3	0.4	2.1	2.0	1.6	2.4	0.6	1.1	1.6	1.9	0.2	1.2	2.0	1.0	1.3	1.8	1.9	1.4	0.6	1.1	1.4	1.4
Serious illness, injury or assault to yourself	1.6	1.9	3.7	-1.8	-1.7	-1.6	-1.4	-0.9	-1.0	-1.5	-1.4	-1.2	-0.8	-1.5	-1.1	-1.0	-1.1	-1.4	-1.5	-1.1	-1.5	-1.7	-1.8	-1.7	-0.7	-1.3	-1.1	-1.9
Medication: Simvastatin	1.6	2.3	6.6	-1.3	-1.7	-0.7	-1.3	-0.8	-2.6	-1.7	-1.6	-2.1	-0.8	-1.4	-1.8	-1.8	0.2	-1.9	-1.8	-1.3	-1.2	-1.6	-1.6	-1.5	-1.0	-1.3	-1.2	-1.6
Happiness	1.6	1.9	5.1	-0.2	0.1	1.1	2.3	2.0	-1.7	-0.3	0.9	0.1	2.0	1.0	1.5	1.9	0.2	-0.2	0.6	2.1	1.8	0.8	0.8	1.2	1.9	2.1	1.7	-1.5
Tense / ‘highly strung’	1.6	2.6	7.6	-0.7	-1.9	-2.2	-1.4	-1.1	-0.6	-1.9	-1.7	-2.0	-0.8	-1.8	-1.5	-1.3	-1.0	-1.5	-1.9	-1.0	-1.8	-1.9	-1.8	-1.9	-1.1	-1.4	-1.5	-2.8
Arm fat-free mass (right)	1.6	8.3	24.0	-3.9	-3.9	-1.2	-0.6	0.6	-4.9	-4.4	-2.5	-4.4	0.0	-2.4	-2.4	-2.5	-2.9	-2.9	-3.6	-0.5	-1.6	-3.3	-3.1	-2.3	-3.2	-1.0	-1.4	-4.0
Eye problems/disorders: Cataract	1.6	1.9	6.1	-2.3	-0.3	-0.7	-1.6	-2.4	0.3	-0.0	-1.4	-0.1	-2.5	-1.6	-0.3	-0.1	-2.1	-1.3	-0.1	-1.1	-1.4	-0.9	-0.9	-1.4	-1.7	-1.0	-1.5	-1.5
Guilty feelings	1.6	2.3	6.8	0.8	0.7	1.0	2.3	2.5	0.3	0.0	1.4	0.4	2.6	1.4	1.6	1.9	1.7	1.1	0.8	1.9	1.6	1.0	1.2	1.4	1.9	2.1	2.0	-0.7
Pack years of smoking	1.6	2.4	4.0	2.0	1.6	1.9	1.8	-0.1	0.2	1.4	1.3	1.6	0.3	1.7	1.9	1.9	0.0	1.7	1.9	1.5	1.6	1.7	1.7	1.7	1.1	1.8	1.3	2.0
Medication for cholesterol, blood pressure or diabetes	1.5	2.4	6.1	1.0	2.1	1.2	1.8	0.4	1.9	1.8	1.5	2.5	0.3	1.4	1.7	1.7	0.1	1.3	1.9	1.0	1.3	1.9	2.0	1.7	1.0	1.3	1.0	2.2
Exposure to tobacco smoke outside home	1.5	2.0	4.0	1.2	1.7	1.5	1.2	0.4	1.0	1.8	1.3	1.3	0.8	1.5	1.3	1.1	1.7	1.7	1.7	1.4	1.1	1.7	1.7	1.5	2.0	1.3	1.0	1.8
Average weekly red wine intake	1.5	2.2	5.5	-1.4	-0.9	-0.8	-0.8	-2.2	-1.0	-0.6	-1.7	-0.5	-2.3	-1.5	-1.3	-1.2	-1.7	-1.8	-1.0	-2.3	-1.6	-1.1	-1.0	-1.4	-2.0	-1.5	-1.7	-1.0
Wears glasses or contact lenses	1.5	1.8	4.0	-0.6	-1.1	-0.8	-1.0	-1.5	-0.4	-0.9	-1.5	-0.8	-1.5	-1.5	-1.0	-0.9	-1.5	-1.4	-1.2	-1.7	-1.9	-1.1	-1.2	-1.6	-2.0	-1.2	-1.7	-1.5
Illnesses of father: High blood pressure	1.5	1.8	8.6	0.8	0.7	0.6	0.8	2.4	1.4	0.8	1.8	0.2	2.9	1.2	0.8	0.7	1.3	1.7	0.8	2.4	1.3	0.9	0.8	1.1	1.0	1.1	1.9	0.3
Depression (Nagel 2018)	1.4	2.1	9.8	1.1	0.2	0.8	3.1	1.6	-0.5	-0.5	1.3	-0.0	2.1	1.5	1.1	1.2	0.9	1.2	0.4	1.5	2.0	0.8	1.1	1.6	1.4	1.9	1.7	1.8
Respiratory disease	1.4	3.2	9.1	-1.8	-2.4	-2.8	-1.8	1.1	-0.7	-2.2	-0.7	-2.3	0.3	-1.7	-2.0	-2.0	-0.2	-1.5	-2.2	-0.7	-0.9	-2.3	-2.4	-1.7	-1.0	-1.7	-0.5	-3.0
Frequency of unenthusiasm / disinterest in last 2 weeks	1.4	1.9	7.2	0.9	0.4	0.9	2.7	1.7	0.4	-0.2	1.4	0.2	2.2	1.4	1.0	1.1	0.9	1.3	0.6	1.3	1.9	0.9	1.2	1.5	1.3	1.7	1.7	1.8
Medication for pain relief, constipation, heartburn	1.4	2.3	9.1	1.4	1.9	0.4	0.4	1.1	2.4	2.6	1.8	2.2	0.6	0.9	1.2	1.1	3.0	1.4	2.0	0.7	0.9	1.5	1.6	1.1	1.5	0.5	1.2	-0.1
Mean time to correctly identify matches	1.4	2.6	10.8	2.2	2.6	0.7	-1.0	-0.5	1.1	3.3	1.6	2.6	-0.1	1.7	1.5	1.2	1.5	1.1	2.4	0.4	0.6	2.2	1.8	1.3	1.7	0.4	1.0	0.4
Arm predicted mass (right)	1.4	7.1	24.6	-3.6	-3.7	-0.9	-0.1	1.2	-5.0	-4.3	-2.1	-4.2	0.5	-1.9	-2.1	-2.1	-2.5	-2.9	-3.3	-0.2	-1.0	-3.0	-2.8	-1.8	-2.8	-0.5	-0.9	-3.7
Hearing aid user	1.4	1.6	2.7	-0.8	-1.6	-1.2	-1.3	-0.8	-1.1	-1.3	-1.2	-1.1	-0.9	-1.6	-1.6	-1.4	-0.5	-0.7	-1.4	-0.8	-1.4	-1.5	-1.5	-1.5	-1.4	-1.4	-1.1	-1.4
Reaction Time	1.3	2.4	7.1	2.3	2.2	0.5	-0.1	0.2	0.8	2.7	1.7	2.1	0.9	1.8	1.5	1.4	1.3	1.3	2.1	0.9	1.0	2.2	1.8	1.5	2.0	1.0	1.4	0.6
Bipolar Disorder (2011)	1.3	1.2	4.0	-1.5	-1.5	-1.1	-0.1	-0.7	-1.2	-2.0	-1.4	-1.6	-0.0	-1.0	-1.2	-0.9	-0.9	-0.4	-1.6	-0.0	-0.9	-1.4	-1.2	-1.0	-1.0	-0.5	-0.8	0.6
Blood Platelet Count	1.3	15.1	27.6	2.9	4.5	2.9	5.2	3.0	2.5	3.9	4.3	3.7	3.0	5.0	4.1	3.9	1.1	3.3	4.0	3.5	3.5	4.8	5.1	4.8	3.2	4.3	3.8	4.3
BMI	1.3	7.3	19.7	-3.4	-4.0	-2.5	-1.6	0.5	-3.1	-3.8	-2.1	-4.4	0.4	-2.4	-2.8	-3.1	-0.8	-1.6	-3.6	-0.3	-1.7	-3.6	-3.5	-2.5	-2.6	-1.7	-1.2	-3.5
Current tobacco smoking	1.3	2.1	14.3	1.6	1.8	2.0	1.1	-1.3	1.0	1.5	0.5	1.7	-0.7	1.1	1.0	1.2	-0.1	1.7	1.6	0.2	0.8	1.9	1.7	1.2	0.5	0.8	0.3	3.8
Frequency of tenseness / restlessness in last 2 weeks	1.3	2.0	3.3	1.6	1.2	1.2	1.5	1.3	1.8	1.0	1.5	0.7	1.5	1.4	1.7	1.7	0.8	1.5	1.5	1.1	1.8	1.2	1.4	1.4	1.7	1.6	1.6	1.0
Diabetes (self-reported)	1.3	2.0	4.9	-1.7	-1.4	-1.5	-1.5	-0.5	-1.9	-1.4	-1.5	-1.8	-1.3	-1.7	-1.3	-1.4	-0.4	-1.6	-1.2	-1.3	-0.8	-1.5	-1.5	-1.4	-0.5	-1.3	-1.4	-2.2
Exposure to tobacco smoke at home	1.3	1.5	4.1	2.0	0.7	0.9	1.3	1.7	1.0	0.3	1.5	0.9	1.8	1.0	0.6	0.6	1.6	1.3	0.6	1.5	1.1	0.8	1.0	1.2	1.1	0.9	1.5	1.7
Diabetes diagnosed by doctor	1.3	2.1	3.9	-1.7	-1.4	-1.7	-1.8	-0.7	-1.8	-1.3	-1.5	-1.7	-1.3	-1.6	-1.6	-1.8	-0.2	-1.4	-1.3	-1.4	-1.0	-1.5	-1.5	-1.4	-0.6	-1.6	-1.4	-2.0
Arm fat mass (left)	1.3	5.5	12.5	-3.1	-3.4	-1.7	-0.8	-0.5	-2.7	-3.4	-2.3	-3.5	-0.5	-2.4	-2.0	-1.8	-2.1	-1.8	-2.9	-0.6	-1.8	-3.1	-3.0	-2.5	-2.0	-1.2	-1.7	-3.2
Frequency of tiredness / lethargy in last 2 weeks	1.2	1.9	7.0	-1.6	-2.1	-1.4	0.4	0.3	-1.9	-2.6	-1.1	-1.7	0.4	-1.2	-1.0	-0.5	-1.6	-1.4	-1.8	-0.1	-0.4	-1.7	-1.6	-1.1	-0.6	-0.3	-0.3	-2.3
Illnesses of mother	1.2	1.5	7.4	1.9	1.7	1.6	0.4	-1.4	1.8	1.7	0.5	1.3	-0.8	1.2	0.9	0.6	0.2	1.6	1.3	0.1	0.1	1.3	1.3	0.9	0.3	0.4	0.0	2.7
Arm fat mass (right)	1.2	5.1	11.5	-3.0	-3.3	-1.8	-0.8	-0.5	-2.5	-3.2	-2.2	-3.4	-0.4	-2.3	-2.0	-1.9	-1.8	-1.7	-2.8	-0.6	-1.8	-3.0	-2.8	-2.3	-1.9	-1.2	-1.6	-3.1
Worry too long after embarrassment	1.2	1.9	6.5	1.7	1.5	0.7	1.8	0.5	0.4	0.9	0.8	1.0	1.0	1.8	1.4	1.5	1.9	0.7	1.2	0.7	1.4	1.7	1.7	1.6	2.5	1.5	1.1	1.2
Eye problems/disorders: None of the above	1.2	1.4	5.1	2.3	0.7	0.9	1.3	1.2	0.3	0.6	1.1	0.5	1.6	1.7	0.3	0.0	1.1	1.7	0.4	0.6	1.1	1.1	1.0	1.5	1.0	0.8	1.1	2.1
Emphysema/chronic bronchitis	1.2	1.3	3.2	-1.4	-1.2	-1.0	-1.0	-1.8	-1.2	-1.2	-1.6	-1.2	-1.4	-0.6	-1.3	-1.4	-0.5	-0.7	-1.3	-1.3	-1.2	-1.2	-1.2	-0.9	-0.4	-1.0	-1.3	0.0
Qualifications: NVQ or HND or HNC or equivalent	1.2	1.5	9.2	-1.8	-1.4	-0.2	-0.4	-0.1	-3.0	-1.7	-1.1	-1.4	-0.1	-0.7	-1.5	-1.5	-0.7	-1.5	-1.6	-0.6	-0.4	-1.0	-1.3	-0.7	-0.5	-0.7	-0.8	-0.6
Knee pain experienced in last month	1.2	1.8	4.4	-2.1	-1.5	-1.6	-0.9	-0.5	-1.7	-1.5	-1.2	-1.2	-1.0	-1.1	-1.6	-1.6	-1.4	-1.0	-1.5	-1.6	-1.1	-1.5	-1.4	-1.1	-1.4	-1.3	-1.2	-0.1
Qualifications: nursing, teaching	1.2	1.9	5.3	-0.3	-0.6	-0.7	-1.9	-2.0	0.9	-0.2	-1.5	-0.3	-2.3	-2.0	-0.5	-0.4	-2.0	-1.0	-0.3	-1.5	-1.7	-1.1	-1.1	-1.7	-2.0	-1.4	-1.7	-1.4
Breast cancer (self-reported)	1.2	1.4	5.8	-0.7	0.0	-0.9	-2.4	-1.9	0.9	0.4	-1.0	0.4	-2.1	-1.3	-0.8	-0.7	-0.6	-1.2	-0.1	-1.8	-1.4	-0.6	-0.9	-1.3	-0.5	-1.7	-1.4	-0.4
Pain experienced in last month	1.2	1.9	13.5	2.2	1.1	0.2	0.2	0.8	2.8	1.4	1.1	0.7	1.1	0.7	1.0	0.8	3.7	1.7	1.2	0.9	0.7	1.0	0.9	0.7	1.7	0.6	1.1	0.7
Crohns Disease (2017)	1.1	2.4	5.3	-2.3	-2.3	-1.4	-0.7	-0.9	-1.0	-2.1	-1.6	-2.3	-0.3	-1.3	-1.9	-1.7	-0.8	-0.6	-2.2	-0.7	-1.7	-2.0	-1.9	-1.7	-1.1	-1.2	-1.4	-1.1
Heel T-Score	1.1	8.8	31.9	2.3	4.2	2.0	0.7	-0.1	5.7	4.9	3.0	4.3	0.6	2.8	2.3	2.0	2.4	3.6	3.7	1.2	1.3	3.4	3.4	2.5	3.0	1.0	1.6	3.8
Body mass index (BMI)	1.1	4.9	13.8	-2.9	-3.4	-1.4	-1.0	-0.2	-2.8	-3.4	-2.1	-3.7	-0.1	-2.1	-1.9	-1.8	-1.2	-1.5	-2.8	-0.3	-1.5	-3.0	-2.9	-2.2	-1.8	-1.0	-1.3	-2.6
Pain all over the body in last month	1.1	1.2	2.6	0.0	-0.8	-0.7	-0.9	-1.5	-1.0	-0.9	-1.2	-0.8	-1.6	-0.9	-1.2	-1.3	-1.5	-1.3	-1.0	-1.5	-0.9	-0.9	-0.9	-1.0	-1.4	-1.4	-1.3	-0.1
Weight	1.1	5.5	13.5	-3.2	-3.4	-1.4	-0.5	0.3	-2.9	-3.5	-2.0	-3.7	0.1	-2.3	-1.9	-1.7	-2.5	-2.1	-2.9	-0.2	-1.5	-3.0	-2.8	-2.2	-2.3	-0.9	-1.3	-3.4
Lung cancer (father)	1.1	1.3	2.8	1.7	1.5	0.8	0.9	0.4	-0.2	1.4	1.6	1.5	0.6	0.7	1.3	1.3	0.6	1.1	1.5	1.6	1.4	1.2	1.4	1.1	0.8	0.8	1.1	-0.3
Migraine (self-reported)	1.1	1.3	4.8	-0.6	-1.6	-1.2	0.2	-1.4	-1.2	-2.0	-1.2	-1.2	-0.6	-1.4	-0.2	0.4	-1.7	-0.6	-1.1	0.0	-0.7	-1.4	-1.3	-1.4	-1.0	-0.0	-0.7	-2.2
Whole body water mass	1.1	6.1	20.1	-3.5	-3.3	-1.1	0.0	1.0	-4.5	-3.9	-1.9	-3.7	0.5	-1.8	-2.0	-1.9	-2.9	-2.8	-3.1	-0.1	-1.0	-2.7	-2.5	-1.7	-2.7	-0.5	-0.8	-3.6
Tinnitus: Yes, now most or all of the time	1.1	1.3	6.5	1.7	1.3	1.3	1.3	0.2	1.2	1.2	1.0	1.7	0.3	0.8	0.7	0.8	0.8	0.5	1.2	0.4	0.9	1.2	1.3	1.1	0.4	0.6	0.8	2.5
Basal metabolic rate	1.1	5.9	16.7	-3.4	-3.4	-1.2	0.1	1.0	-4.1	-3.8	-1.8	-3.6	0.6	-1.9	-1.9	-1.8	-2.9	-2.7	-3.0	-0.0	-1.0	-2.8	-2.5	-1.8	-2.6	-0.5	-0.8	-3.6
Arm fat-free mass (left)	1.1	5.7	20.5	-3.4	-3.2	-0.8	0.1	1.0	-4.5	-3.8	-1.9	-3.9	0.5	-1.6	-1.7	-1.8	-2.5	-2.6	-2.9	0.2	-0.9	-2.5	-2.3	-1.5	-2.3	-0.2	-0.7	-3.6
Heart attack/myocardial infarction (self-reported)	1.1	1.5	4.3	-1.7	-1.3	-1.2	-0.4	-0.8	-2.1	-1.6	-1.3	-1.8	-0.4	-0.8	-1.5	-1.5	-1.2	-0.4	-1.7	-0.6	-1.2	-1.2	-1.1	-1.0	-1.2	-0.8	-1.2	-0.1
Verbal and Numeric Reasoning (VNR)	1.0	2.4	12.5	-0.6	2.2	0.4	-0.6	-1.5	3.5	3.3	0.8	3.1	-1.8	-0.0	0.7	0.7	-1.5	0.1	1.9	-0.9	-0.7	1.3	1.3	-0.1	-1.1	-1.0	-0.6	0.9
Ovarian Cancer	1.0	1.3	3.1	-1.2	-1.0	-1.4	-1.6	-1.1	-0.0	-0.5	-0.9	-0.8	-1.4	-1.3	-1.2	-1.1	0.0	-0.9	-0.7	-1.3	-1.1	-1.2	-1.4	-1.6	-0.8	-1.8	-1.1	-1.4
Rheumatoid Arthritis	1.0	1.4	4.6	0.2	1.6	0.4	-0.2	0.4	0.7	1.8	1.4	1.6	0.1	1.3	1.0	0.7	2.2	1.5	1.7	0.8	1.2	1.3	1.3	1.2	1.5	0.4	0.8	0.6
Hayfever, allergic rhinitis or eczema	1.0	2.2	6.4	-2.1	-1.9	-2.5	-1.9	0.3	-0.2	-1.8	-1.0	-1.6	-0.2	-1.8	-1.4	-1.2	-0.9	-1.3	-1.7	-0.8	-1.1	-2.0	-2.0	-1.7	-0.8	-1.4	-0.9	-1.4
Leg predicted mass (left)	1.0	5.1	11.8	-3.1	-3.1	-1.4	-0.6	0.8	-3.0	-3.3	-1.7	-3.0	0.2	-2.2	-1.9	-1.7	-2.7	-2.5	-2.7	-0.4	-1.2	-2.7	-2.6	-2.0	-2.7	-1.0	-0.9	-3.4
Trunk fat mass	1.0	4.2	9.3	-2.6	-3.1	-1.6	-0.9	-0.5	-1.6	-2.8	-1.9	-3.0	-0.5	-2.4	-1.6	-1.4	-1.9	-1.3	-2.5	-0.5	-1.8	-2.9	-2.7	-2.4	-1.8	-1.1	-1.6	-2.9
Alcohol usually taken with meals	1.0	1.6	5.5	-0.5	-1.6	-0.6	-0.5	-0.4	-1.0	-1.6	-1.4	-1.3	-0.4	-1.6	-1.5	-1.5	-1.0	-1.7	-1.6	-0.7	-1.2	-1.5	-1.4	-1.3	-2.3	-1.2	-1.0	-0.8
Father’s age at death	1.0	1.4	4.3	0.7	1.3	0.4	0.7	0.8	2.1	1.5	1.2	1.4	0.7	1.0	0.9	0.9	2.0	1.0	1.1	0.7	0.5	1.1	1.3	1.0	2.0	0.8	0.8	1.4
Prospective memory result	1.0	1.2	6.0	-1.2	-1.6	-1.7	-1.0	-0.6	-0.7	-1.0	-0.9	-2.4	-0.5	-0.8	-0.9	-1.3	-0.5	0.3	-1.2	-0.2	-0.7	-1.5	-1.4	-1.2	-0.5	-0.9	-1.0	-1.1
Leg fat mass (right)	1.0	4.0	9.8	-2.6	-3.1	-1.5	-1.1	-0.1	-2.0	-2.8	-1.7	-3.1	-0.1	-2.2	-1.8	-1.7	-1.1	-1.2	-2.5	-0.2	-1.5	-2.8	-2.7	-2.2	-1.7	-1.2	-1.3	-2.9
Whole body fat-free mass	1.0	6.0	19.6	-3.4	-3.3	-1.1	0.1	1.2	-4.4	-3.9	-1.8	-3.6	0.7	-1.8	-1.9	-1.8	-2.9	-2.8	-3.0	-0.1	-0.9	-2.7	-2.5	-1.6	-2.6	-0.5	-0.7	-3.7
Arm fat percentage (left)	1.0	4.0	8.4	-2.4	-2.9	-1.9	-1.2	-1.0	-1.4	-2.6	-2.0	-2.7	-0.8	-2.3	-1.8	-1.6	-1.2	-1.1	-2.4	-0.8	-1.9	-2.8	-2.7	-2.4	-1.6	-1.4	-1.7	-2.6
Loneliness, isolation	1.0	1.4	6.4	-1.4	-1.3	-2.5	-0.7	0.1	-0.7	-1.2	-0.5	-1.1	-0.1	-1.2	-1.3	-1.1	-0.5	-1.2	-1.2	-1.0	-0.7	-1.5	-1.1	-1.1	-1.0	-1.1	-0.5	-2.2
Leg predicted mass (right)	1.0	5.1	12.4	-3.1	-3.1	-1.2	-0.3	0.8	-3.2	-3.5	-1.7	-3.0	0.4	-2.1	-1.9	-1.6	-2.9	-2.6	-2.8	-0.4	-1.1	-2.7	-2.6	-1.9	-2.7	-0.8	-0.8	-3.2
Pain type(s) experienced in last month: Hip pain	1.0	1.3	4.3	0.1	0.8	1.2	2.1	0.2	-0.4	0.4	0.8	1.1	0.5	1.3	1.6	1.8	-1.5	1.5	0.8	1.5	0.9	1.0	1.0	1.1	0.7	1.6	1.0	1.1
Unable to work because of sickness or disability	1.0	1.3	4.2	-0.1	0.7	1.0	2.1	1.2	-0.8	-0.1	0.9	0.3	1.4	1.5	1.2	1.3	-0.5	0.6	0.6	1.5	1.4	1.1	1.1	1.4	1.3	1.7	1.1	1.3
Arm predicted mass (left)	1.0	5.3	20.1	-3.4	-3.1	-0.8	0.2	1.0	-4.5	-3.7	-1.9	-3.7	0.5	-1.5	-1.6	-1.5	-2.7	-2.4	-2.8	0.3	-0.8	-2.5	-2.2	-1.4	-2.2	-0.1	-0.7	-3.4
Lung FVC	0.9	4.7	16.4	1.6	3.3	1.7	1.4	-0.3	2.4	3.6	2.0	4.1	-0.9	1.6	2.5	2.8	-0.5	1.4	3.2	0.5	1.1	2.9	2.8	1.9	0.5	1.4	1.1	2.0
Leg fat-free mass (left)	0.9	4.8	11.7	-3.0	-3.0	-1.2	-0.5	0.8	-3.0	-3.3	-1.6	-3.0	0.3	-2.1	-1.8	-1.6	-2.7	-2.4	-2.6	-0.3	-1.1	-2.7	-2.5	-1.9	-2.7	-0.9	-0.8	-3.4
Qualifications: CSEs or equivalent	0.9	1.2	3.5	-0.4	-1.7	-1.0	-0.5	-0.4	-0.9	-1.8	-1.3	-1.9	-0.1	-1.1	-1.3	-1.3	0.4	-1.0	-1.6	-0.4	-1.0	-1.4	-1.5	-1.1	-0.6	-0.7	-0.9	-0.8
Trunk fat-free mass	0.9	5.0	23.8	-3.0	-2.9	-0.7	0.8	1.5	-4.9	-3.7	-1.5	-3.5	1.0	-1.1	-1.5	-1.5	-2.7	-2.6	-2.7	0.4	-0.4	-2.1	-1.9	-1.0	-2.1	0.1	-0.3	-3.3
Trunk predicted mass	0.9	5.1	24.0	-3.0	-2.9	-0.7	0.8	1.5	-4.9	-3.7	-1.5	-3.5	1.0	-1.1	-1.5	-1.5	-2.6	-2.6	-2.7	0.4	-0.4	-2.1	-1.9	-1.0	-2.1	0.1	-0.3	-3.4
Mouth/teeth dental problems: Bleeding gums	0.9	1.2	3.2	-1.2	-1.5	-1.6	0.2	0.3	-1.3	-1.7	-0.7	-1.8	0.6	-0.5	-1.0	-1.0	-1.5	-0.3	-1.5	-0.2	-0.6	-1.3	-1.1	-0.8	-1.0	-0.4	-0.3	-1.5
Glaucoma (self-reported)	0.9	1.1	3.7	0.9	0.9	0.9	0.8	1.0	1.9	1.2	1.4	0.8	0.8	1.1	0.9	0.6	0.4	1.4	1.2	0.9	1.1	0.9	0.9	0.8	0.7	0.5	1.1	1.4
Leg fat-free mass (right)	0.9	5.0	12.1	-3.1	-3.1	-1.2	-0.3	0.8	-3.2	-3.5	-1.6	-3.0	0.4	-2.1	-1.8	-1.6	-2.9	-2.6	-2.7	-0.3	-1.1	-2.7	-2.5	-1.8	-2.7	-0.8	-0.8	-3.2
Long-standing illness, disability or infirmity	0.9	1.4	5.2	-1.4	-1.5	-0.6	-0.0	-0.4	-2.3	-1.8	-1.2	-1.5	-0.2	-0.8	-1.3	-1.1	-0.3	-1.7	-1.5	-1.0	-0.7	-1.1	-1.1	-1.0	-0.1	-0.7	-0.8	-2.0
Financial situation satisfaction	0.9	1.1	4.8	0.5	0.6	1.2	2.2	1.4	-0.4	0.2	1.1	0.9	1.3	1.1	0.9	1.1	-0.2	0.4	0.6	1.6	1.0	0.9	1.0	1.2	0.6	1.3	1.4	0.5
Waist Hip Ratio (WHR)	0.8	3.8	6.9	2.3	2.4	1.5	1.2	1.5	1.0	2.1	1.9	2.5	1.2	1.5	1.9	2.0	2.5	1.5	2.5	1.8	2.1	2.4	2.2	2.0	2.6	1.5	1.9	1.2
Medication: Metformin	0.8	1.2	2.9	-0.7	-0.9	-1.0	-1.5	-0.5	-1.3	-0.7	-1.1	-1.2	-0.9	-1.0	-1.4	-1.7	0.1	-1.2	-1.0	-1.3	-0.8	-1.0	-1.1	-1.0	-0.7	-1.4	-1.2	-0.8
Trunk fat percentage	0.8	3.2	7.1	-2.1	-2.7	-1.6	-1.1	-0.8	-0.5	-2.3	-1.8	-2.5	-0.7	-2.4	-1.4	-1.1	-1.4	-0.9	-2.1	-0.7	-1.8	-2.7	-2.5	-2.4	-1.4	-1.2	-1.7	-2.2
Hair/balding pattern: Pattern 2	0.8	1.0	2.4	1.3	-0.2	1.1	1.5	1.5	-1.3	-1.2	0.4	-0.0	1.6	0.8	0.8	0.7	1.2	0.6	-0.1	1.0	1.3	0.1	0.2	1.0	1.1	1.5	1.2	-0.1
Had other major operations	0.8	0.9	4.4	-0.3	0.8	-0.1	-1.2	-2.0	1.3	1.3	-0.5	0.8	-2.1	-0.2	-0.3	-0.5	-0.2	0.4	0.5	-1.5	-1.1	0.2	0.2	-0.6	0.1	-1.2	-1.3	0.9
Qualifications: None of the above	0.8	1.7	5.5	-1.1	-1.5	-1.1	-2.3	-1.2	-1.8	-1.5	-1.5	-2.3	-1.1	-0.6	-1.2	-1.6	0.1	-0.6	-1.4	-1.1	-0.6	-1.4	-1.6	-1.0	-0.0	-1.0	-1.1	-0.3
Arm fat percentage (right)	0.8	3.0	6.7	-2.3	-2.6	-1.9	-0.8	-0.9	-1.2	-2.3	-1.8	-2.6	-0.6	-1.9	-1.4	-1.3	-1.2	-0.8	-2.1	-0.5	-1.7	-2.4	-2.3	-2.1	-1.2	-1.1	-1.5	-2.2
Hip circumference	0.8	3.5	8.1	-2.8	-2.7	-1.4	-0.4	0.3	-1.4	-2.6	-1.4	-2.8	0.1	-2.0	-1.7	-1.6	-2.0	-1.5	-2.2	-0.2	-1.3	-2.5	-2.2	-1.9	-2.2	-1.0	-1.2	-2.5
Whole body fat mass	0.8	3.5	8.1	-2.6	-2.8	-1.3	-0.6	-0.3	-1.7	-2.7	-1.7	-2.9	-0.3	-2.1	-1.4	-1.2	-1.8	-1.2	-2.3	-0.2	-1.5	-2.6	-2.4	-2.1	-1.7	-0.9	-1.4	-2.8
Ever had stillbirth, spontaneous miscarriage or termination	0.8	0.8	2.5	1.1	1.2	-0.7	0.5	1.0	1.6	1.3	1.3	1.2	0.8	0.7	-0.1	-0.4	1.4	0.5	1.0	0.6	0.7	1.0	0.9	0.8	0.2	-0.4	0.8	0.1
Osteoarthritis (self-reported)	0.8	1.0	3.9	-2.0	-0.6	-1.1	-1.5	-1.3	-1.0	-0.1	-0.9	-1.0	-1.6	-0.7	-0.7	-1.0	-1.3	-0.4	-0.4	-1.1	-0.7	-0.8	-0.9	-0.9	-0.4	-1.1	-1.2	-0.4
Leg fat mass (left)	0.8	3.2	8.7	-2.4	-2.8	-1.2	-0.7	0.0	-1.9	-2.7	-1.5	-3.0	0.1	-1.9	-1.4	-1.3	-1.1	-1.1	-2.3	0.1	-1.3	-2.5	-2.4	-1.9	-1.4	-0.7	-1.1	-2.5
Age at First Birth	0.7	1.0	5.2	-0.1	1.3	0.0	0.4	-0.3	2.0	1.7	0.8	1.7	-0.0	0.2	0.9	1.1	-2.3	0.8	1.3	0.3	-0.2	1.0	1.0	0.3	-0.3	0.3	-0.0	-0.1
Other serious medical condition/disability diagnosed by doctor	0.7	0.9	2.3	0.3	1.2	0.2	1.0	0.6	0.4	1.1	1.0	1.1	0.7	1.5	0.9	0.7	0.3	0.9	1.0	0.7	0.9	1.2	1.2	1.2	1.1	0.8	1.0	0.7
Vitamin and mineral supplements	0.7	0.9	2.5	0.9	0.6	0.7	0.5	0.8	1.0	0.6	0.8	0.6	1.1	0.7	1.2	1.3	1.2	1.2	0.9	1.6	0.9	0.9	0.7	0.8	0.7	1.2	1.2	1.2
Heel bone mineral density (BMD) T-score, automated (left)	0.7	1.5	8.2	1.6	1.6	1.1	-0.2	-1.1	2.9	2.0	0.6	1.4	-0.3	0.9	1.0	0.9	0.7	1.3	1.5	-0.3	-0.1	1.3	1.2	0.4	1.1	0.1	0.2	2.0
Diverticular disease/diverticulitis (self-reported)	0.7	0.9	2.1	-1.4	-1.0	-0.4	-0.9	-1.4	-0.9	-0.9	-1.3	-1.1	-0.8	-0.7	-1.0	-1.0	0.1	-0.5	-1.1	-0.8	-1.0	-1.0	-1.0	-0.8	-0.5	-0.7	-1.0	0.1
Heart attack	0.7	0.9	2.9	-1.3	-0.9	-0.9	-0.2	-0.8	-1.7	-1.2	-1.1	-1.4	-0.3	-0.5	-1.1	-1.1	-0.9	-0.2	-1.3	-0.3	-1.0	-0.8	-0.7	-0.7	-0.8	-0.5	-0.9	0.2
Impedance of arm (right)	0.7	3.3	18.7	2.1	2.5	-0.2	0.6	-0.4	4.3	3.0	1.6	3.2	-0.2	1.0	1.6	1.8	0.7	1.6	2.3	0.2	0.6	1.9	1.8	1.1	1.9	0.3	0.6	1.8
Pulse rate	0.7	1.1	3.4	0.7	0.9	0.8	1.8	0.8	0.5	0.4	1.1	1.3	1.2	1.2	1.0	1.2	0.6	1.6	0.7	1.2	0.9	1.1	1.2	1.2	0.7	1.2	1.0	0.6
Depression (self-reported)	0.7	0.8	1.8	-1.3	-1.3	-0.3	-0.4	-0.8	-0.7	-1.3	-1.1	-1.3	-0.2	-1.1	-1.1	-0.7	0.1	-0.5	-1.1	-0.8	-0.9	-1.2	-1.1	-1.0	-0.2	-0.6	-1.0	-0.1
Forced vital capacity (FVC), Best measure	0.7	2.4	6.3	1.5	2.1	0.8	1.8	0.9	1.8	1.9	1.4	2.5	0.4	0.8	1.9	2.1	-1.9	0.7	2.0	1.0	1.2	1.9	2.0	1.5	-0.3	1.4	1.2	0.6
Body fat percentage	0.7	2.9	6.8	-2.1	-2.6	-1.5	-1.1	-0.6	-0.7	-2.2	-1.6	-2.6	-0.5	-2.1	-1.3	-1.1	-1.0	-0.6	-2.0	-0.3	-1.6	-2.5	-2.4	-2.2	-1.2	-1.0	-1.5	-2.2
Leg fat percentage (right)	0.7	2.4	7.1	-1.9	-2.5	-1.3	-1.3	-0.2	-1.0	-2.0	-1.3	-2.7	-0.3	-1.8	-1.3	-1.3	-0.0	-0.5	-1.8	-0.1	-1.3	-2.3	-2.3	-2.0	-0.9	-1.0	-1.1	-2.2
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.8	1.9	0.5	0.5	1.0	1.4	1.2	-0.0	0.2	0.8	0.1	1.4	0.9	0.9	0.8	0.5	0.6	0.5	1.3	1.2	0.8	0.9	1.0	0.7	1.2	1.1	0.9
Chest pain or discomfort	0.7	1.0	5.4	-0.3	0.1	0.5	2.3	1.3	-1.9	-0.5	1.0	0.3	1.3	0.9	0.4	0.7	-1.0	0.2	0.0	1.3	1.1	0.6	0.7	1.0	0.8	1.1	1.0	-0.5
Age at last live birth	0.7	1.0	6.7	1.1	1.3	0.4	0.5	0.3	2.6	1.3	1.2	1.9	0.2	0.3	0.9	1.0	-0.2	1.0	1.2	0.1	0.4	1.0	1.0	0.4	-0.1	0.1	0.6	0.7
Family relationship satisfaction	0.7	0.9	3.8	-0.9	0.1	0.2	1.9	1.4	-1.5	-0.3	0.6	0.3	1.4	0.7	0.6	0.9	0.0	-0.7	0.2	1.2	1.1	0.5	0.5	0.8	0.9	1.2	1.0	-0.9
Medication: Aspirin	0.7	0.9	2.6	-0.4	-0.6	0.2	-0.6	-1.6	-1.6	-0.8	-1.3	-0.7	-1.5	-0.4	-0.9	-1.0	-1.1	-1.1	-0.9	-1.1	-1.0	-0.6	-0.5	-0.7	-0.3	-0.8	-1.3	0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.8	1.4	-0.6	-0.7	-0.8	-1.2	-1.2	-0.9	-0.7	-1.0	-0.6	-1.0	-0.8	-1.1	-1.1	-0.8	-0.9	-0.9	-1.0	-1.0	-0.8	-0.9	-0.8	-0.7	-1.1	-1.1	-0.2
Handedness (chirality/laterality): Left-handed	0.7	0.8	2.2	1.3	0.6	0.9	0.5	1.0	1.0	0.5	1.0	0.2	0.9	0.5	1.0	0.9	1.5	1.1	0.9	1.1	1.1	0.6	0.6	0.7	0.6	0.8	1.1	0.7
Back pain experienced in last month	0.7	1.0	6.2	-2.2	-0.7	-0.3	0.6	-0.5	-1.4	-1.4	-1.1	-0.4	-0.5	-0.5	-0.5	-0.2	-2.5	-1.5	-1.0	-0.6	-0.6	-0.7	-0.5	-0.3	-0.9	0.0	-0.8	-0.1
Medication: Lisinopril	0.7	0.9	1.7	-0.8	-1.0	-0.9	-0.9	-0.9	-1.1	-0.8	-1.1	-1.1	-0.9	-1.3	-0.7	-0.6	-0.3	-0.4	-0.8	-0.8	-1.1	-0.9	-0.8	-1.2	-0.9	-0.7	-1.1	-1.3
Leg fat percentage (left)	0.7	2.5	7.7	-1.9	-2.5	-1.1	-1.0	-0.3	-1.1	-2.2	-1.4	-2.8	-0.3	-1.8	-1.2	-1.1	-0.2	-0.6	-1.9	-0.0	-1.3	-2.3	-2.3	-1.9	-0.8	-0.8	-1.2	-2.0
Average weekly beer plus cider intake	0.7	1.1	2.6	-0.0	1.2	1.1	1.4	0.4	0.4	0.9	1.0	1.6	0.6	1.0	0.9	1.1	-1.2	1.1	1.1	1.1	1.2	1.3	1.1	1.2	0.6	0.9	0.5	1.6
Diastolic blood pressure, automated reading	0.7	2.0	7.7	-1.5	-1.6	0.0	1.2	2.8	-2.4	-2.5	0.4	-1.9	2.4	-0.2	0.3	0.8	-0.5	-0.2	-0.9	2.0	1.3	-0.8	-0.8	0.2	0.4	1.6	1.2	-1.3
Ever depressed for a whole week	0.7	0.9	2.2	0.4	1.0	0.4	1.5	1.2	-0.5	0.8	1.1	0.9	1.1	1.3	0.6	0.7	-0.0	0.4	0.7	1.3	0.9	1.2	1.2	1.2	0.4	1.0	1.2	-0.5
Depressed Affect (Nagel 2018)	0.6	1.2	4.5	-0.8	-1.7	-2.1	0.1	0.3	-1.2	-1.8	-0.6	-1.7	0.4	-1.0	-0.9	-0.8	0.1	-0.8	-1.4	-0.4	-0.5	-1.5	-1.4	-1.1	-0.3	-0.6	-0.4	-1.8
Fasting Glucose	0.6	0.8	2.6	-0.3	-1.0	-0.6	-1.2	-0.5	-0.9	-0.7	-0.8	-1.0	-1.1	-1.0	-0.5	-0.6	-0.8	-0.7	-0.6	-0.3	-0.6	-1.1	-1.3	-1.1	-0.6	-0.9	-0.7	-1.6
Systolic Blood Pressure	0.6	3.2	8.6	1.4	-0.1	2.0	1.4	2.7	-1.1	-1.1	1.2	-0.4	2.4	1.0	2.1	2.6	1.5	0.9	0.8	2.9	2.6	0.8	0.4	1.3	2.9	2.8	2.0	0.8
Frequency of depressed mood in last 2 weeks	0.6	0.9	5.1	0.3	0.1	0.6	2.3	0.8	-0.0	-0.4	0.7	-0.1	1.4	0.8	1.0	1.3	-0.1	0.4	0.3	1.3	1.2	0.4	0.7	0.8	1.0	1.5	1.1	0.7
Hand grip strength (right)	0.6	1.6	7.5	-0.6	-1.9	0.9	1.3	1.6	-2.7	-2.7	-0.8	-1.7	1.1	-0.6	-0.9	-0.7	-0.5	-1.6	-1.7	0.3	0.5	-1.2	-1.1	-0.2	-1.1	0.5	0.1	-0.7
Multivitamins +/- minerals	0.6	0.8	1.4	-1.2	-0.8	-0.5	-0.6	-0.8	-1.1	-0.9	-0.9	-0.7	-0.9	-0.9	-1.1	-1.1	-0.8	-1.0	-1.0	-1.1	-0.9	-0.9	-0.8	-0.7	-0.5	-0.8	-1.2	-0.9
Medication: Atenolol	0.6	0.8	5.9	-0.8	-0.8	0.1	-1.0	0.2	-2.4	-0.9	-0.7	-0.6	-0.2	-0.3	-1.1	-1.1	0.8	-1.2	-1.0	-0.8	-0.5	-0.7	-0.8	-0.4	0.1	-0.6	-0.6	-1.0
Mouth/teeth dental problems	0.6	1.0	2.9	-0.2	-0.5	0.3	-1.7	-0.8	0.4	-0.4	-1.3	-0.6	-1.2	-1.5	-0.9	-0.9	1.0	-1.2	-0.6	-1.4	-1.3	-0.7	-0.9	-1.1	-0.3	-1.1	-1.5	0.1
Fluid intelligence score	0.6	1.3	6.7	0.0	1.6	1.0	-0.1	-0.5	2.6	2.3	1.1	2.5	-0.8	0.0	0.7	0.8	-0.6	0.5	1.7	-0.2	0.0	1.1	1.0	0.2	-0.8	-0.4	0.2	0.4
Time employed in main current job	0.6	0.7	3.6	-0.5	0.7	1.0	0.1	1.9	0.2	0.7	1.2	0.4	1.5	0.7	0.4	0.2	-0.6	0.4	0.8	0.9	1.2	0.8	0.6	1.0	0.3	0.6	1.1	0.6
Qualifications: O levels/GCSEs or equivalent	0.6	0.9	4.3	0.9	1.4	1.2	1.0	-0.2	1.7	1.4	0.5	2.1	-0.1	0.3	0.9	1.0	-0.8	0.5	1.2	0.2	-0.0	1.1	1.2	0.7	-0.0	0.5	0.2	1.0
Health satisfaction	0.6	0.8	4.0	-1.3	0.1	0.8	1.5	0.9	-2.0	-0.3	0.3	0.2	0.6	1.2	0.6	0.7	-1.0	-0.7	0.1	0.6	0.9	0.6	0.5	1.0	1.4	1.2	0.6	-0.7
Shortness of breath walking on level ground	0.6	0.7	2.0	0.2	0.4	0.6	1.2	0.2	-0.9	0.3	0.5	0.2	0.5	1.4	1.1	1.0	-0.1	1.3	0.4	1.2	0.7	0.5	0.7	0.9	1.4	1.3	0.9	-0.1
Medication: Seretide 50 evohaler	0.6	0.7	4.0	0.2	0.6	0.2	0.1	0.9	0.4	0.6	0.6	-0.2	1.3	1.5	0.3	-0.1	2.0	0.9	0.3	0.5	0.5	0.8	0.6	1.0	1.7	0.7	0.8	0.1
Leg pain on walking	0.6	0.7	4.1	0.6	0.5	1.1	1.2	0.4	-0.2	0.1	0.5	0.9	0.4	1.0	0.5	0.5	1.6	0.8	0.3	0.4	0.7	0.5	0.7	0.9	1.1	0.7	0.8	2.0
Smoking status: Previous	0.6	0.9	2.8	0.5	1.5	1.1	0.0	-1.4	1.3	1.7	0.0	1.5	-1.3	0.7	0.8	0.7	0.1	0.3	1.3	-1.1	-0.1	1.1	1.1	0.5	1.0	0.1	-0.3	0.4
Medication: Gliclazide	0.6	0.6	1.8	-1.0	-0.9	-0.1	-0.1	-0.1	-1.2	-1.1	-1.0	-1.2	-0.2	-0.4	-1.1	-1.4	-0.2	-0.7	-1.1	-0.9	-0.3	-0.8	-0.7	-0.4	-0.7	-0.5	-0.6	0.8
Illnesses of father: None of the above (group 1)	0.6	0.8	3.0	0.2	1.1	-0.2	-0.9	-1.5	1.7	1.4	-0.0	1.4	-1.5	-0.2	1.0	1.2	-0.3	-0.3	1.2	0.0	-0.3	0.6	0.5	-0.1	-0.1	-0.0	-0.1	0.8
Supplements: Fish oil (including cod liver oil)	0.6	0.8	5.1	-0.8	-0.5	0.4	0.1	-0.8	-2.3	-1.3	-1.0	-0.4	-1.0	-0.5	-0.3	-0.1	-1.5	-1.6	-0.6	-0.6	-0.2	-0.5	-0.4	-0.2	0.0	0.1	-0.9	-0.9
Medication: Atorvastatin	0.6	0.7	1.9	-0.8	-0.5	-0.2	-0.7	-1.0	-1.0	-0.7	-1.1	-0.4	-1.4	-0.8	-0.7	-0.6	-1.1	-1.1	-0.5	-1.1	-0.9	-0.6	-0.7	-0.8	-0.6	-0.8	-1.2	-1.1
Number of operations (self-reported)	0.6	0.9	4.8	-0.2	-0.2	-0.8	-1.1	-2.2	-0.8	0.1	-1.1	-0.2	-1.9	-0.4	-0.8	-0.9	-1.1	0.1	-0.3	-1.3	-1.1	-0.3	-0.5	-0.8	-0.5	-1.2	-1.5	0.2
Worry (Nagel 2018)	0.5	1.1	4.5	0.9	-0.2	-0.2	0.9	1.7	0.2	-0.7	0.8	-0.7	2.1	0.6	0.3	0.5	1.9	1.0	-0.1	1.1	1.3	0.2	0.2	0.7	2.1	1.0	1.0	0.4
Prostate Cancer	0.5	0.7	3.2	1.4	0.8	0.9	0.1	-0.4	1.8	1.0	0.7	0.8	0.3	0.6	1.1	1.3	0.3	0.9	0.8	0.6	0.4	0.8	0.7	0.3	0.9	0.6	0.7	-0.6
Lupus	0.5	0.7	2.2	-0.6	-0.7	-0.2	-0.9	-1.5	-0.6	-0.6	-1.3	-0.8	-1.2	-0.2	-0.9	-0.9	-0.4	-0.7	-0.9	-1.4	-1.4	-0.8	-1.0	-0.7	-0.3	-0.6	-0.7	-0.1
Lung FEV1/FVC ratio	0.5	2.4	11.6	0.3	-0.3	1.0	1.7	3.3	-0.5	-0.8	1.3	-0.4	3.4	1.0	0.8	1.1	2.4	1.1	-0.0	2.7	1.5	0.3	0.5	1.2	1.6	1.9	2.0	-0.3
Impedance of leg (right)	0.5	2.6	8.2	2.2	1.9	0.7	1.1	0.3	2.9	2.4	1.6	2.0	0.5	1.3	1.5	1.5	1.4	2.1	1.9	1.0	1.1	1.8	1.8	1.4	1.8	0.9	0.9	1.5
Tinnitus: Yes, but not now, but have in the past	0.5	0.6	1.7	0.3	0.8	0.5	1.3	0.2	-0.2	0.6	0.5	0.8	0.9	1.2	0.9	0.9	-0.3	0.4	0.4	0.3	0.3	1.1	1.0	1.0	0.7	1.2	0.7	0.6
High blood pressure (mother)	0.5	0.7	4.1	-0.4	-0.7	0.3	0.8	2.0	-1.2	-1.1	0.4	-0.6	1.5	0.2	0.2	0.2	0.4	-0.1	-0.3	1.3	1.1	-0.1	-0.3	0.5	0.2	0.9	1.1	-0.1
Impedance of leg (left)	0.5	2.5	7.0	2.1	1.7	0.9	1.5	0.4	2.6	1.9	1.4	1.7	0.7	1.4	1.5	1.6	1.4	1.9	1.7	1.2	1.1	1.8	1.7	1.4	2.1	1.3	0.8	1.9
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.2	5.8	1.4	1.4	1.1	0.3	-0.3	2.4	1.7	1.0	1.2	0.3	1.3	0.7	0.5	0.9	1.3	1.2	-0.4	0.2	1.2	1.1	0.7	1.0	0.1	0.5	1.8
Illnesses of siblings	0.5	0.7	3.9	0.3	0.1	0.2	-0.4	-2.0	1.9	0.3	-1.1	0.3	-1.6	-0.7	0.2	0.1	0.0	0.5	-0.0	-0.9	-1.3	-0.4	-0.1	-0.7	-0.4	-0.3	-1.2	1.1
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.5	2.5	0.4	0.9	1.1	1.0	0.2	-0.2	0.6	0.1	0.7	-0.1	0.8	0.6	0.5	-0.5	-0.3	0.7	0.5	0.5	0.9	1.1	1.0	0.5	0.8	0.3	1.6
Medication: Lansoprazole	0.5	0.6	2.0	0.1	0.1	0.3	1.1	1.0	-0.9	-0.4	0.5	-0.3	0.9	-0.0	1.1	1.4	0.0	0.0	0.6	1.3	1.3	0.3	0.3	0.4	0.8	1.2	0.9	-0.1
Length of working week for main job	0.5	0.5	1.9	-0.6	-0.6	-0.6	-0.2	0.0	-1.4	-0.5	-0.6	-0.9	-0.5	-0.2	-0.6	-0.9	-1.0	-1.2	-0.6	-0.9	-0.5	-0.5	-0.5	-0.4	-1.1	-0.5	-0.3	-1.0
Breastfed as a baby	0.5	0.6	1.8	1.1	1.1	0.3	0.2	-0.7	1.1	1.1	0.3	1.4	-0.8	0.1	1.2	1.3	-0.5	0.2	1.3	0.4	0.1	0.6	0.8	0.2	0.6	0.3	0.2	-0.8
Medication: Paracetamol	0.5	0.8	3.6	-0.4	-1.1	0.8	1.0	0.1	-1.9	-1.8	-0.8	-1.4	0.2	-0.1	0.5	0.6	-1.6	-0.5	-0.7	0.5	0.5	-0.5	-0.6	-0.2	-0.8	1.0	0.2	-0.4
Hypothyroidism/myxoedema (self-reported)	0.5	1.0	6.0	-1.4	-0.3	0.0	-1.4	-1.6	-1.7	0.0	-1.1	-0.3	-1.2	-0.2	-0.4	-0.4	-2.5	-0.7	-0.3	-1.3	-0.7	-0.4	-0.5	-0.4	-1.1	-0.3	-1.1	-0.8
High blood pressure (siblings)	0.5	0.7	4.0	-0.8	-1.0	-0.5	-0.3	1.1	-2.0	-1.1	-0.0	-1.3	1.1	0.2	-1.2	-1.3	0.5	-0.6	-1.1	0.3	0.3	-0.5	-0.8	-0.1	-0.1	-0.3	0.3	-0.4
Neck or shoulder pain in last month	0.5	0.7	5.9	-1.3	-0.3	0.4	0.9	-1.1	-1.2	-0.5	-0.7	0.0	-1.2	0.1	-0.3	-0.3	-2.4	-0.9	-0.5	-1.0	-0.4	-0.3	-0.1	-0.2	-0.9	-0.2	-0.8	-0.4
Medication: Allopurinol	0.5	0.6	2.5	0.1	-0.8	-0.8	-0.7	-0.6	-0.4	-0.7	-0.5	-0.2	-0.5	-1.0	-0.7	-0.7	-1.0	-0.3	-0.9	-0.2	-0.9	-1.0	-0.9	-0.9	-0.8	-0.9	-0.5	-1.6
Number of full sisters	0.5	0.6	3.1	0.3	0.1	1.2	1.3	-0.5	-0.8	-0.2	0.1	0.1	0.3	1.0	0.6	0.6	-0.1	1.0	0.1	0.9	0.5	0.5	0.4	0.7	1.1	1.2	-0.1	1.8
Commuting to job workplace: Car/motor vehicle	0.5	0.6	5.5	-0.8	-1.1	0.1	0.6	0.7	-2.3	-1.3	-0.3	-1.2	0.5	-0.2	-0.7	-0.6	-0.7	-0.8	-0.8	0.3	0.2	-0.6	-0.6	0.0	-0.2	0.3	-0.0	-0.4
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	4.4	1.2	0.7	0.2	-0.6	-0.7	2.1	1.2	0.2	0.8	-0.4	0.1	0.2	0.1	1.8	0.6	0.5	-0.2	-0.5	0.5	0.3	-0.1	0.5	-0.4	-0.2	0.6
Mood swings	0.5	0.9	4.8	-0.4	-1.8	-1.0	0.6	0.3	-1.0	-2.2	-0.7	-1.8	0.7	-0.7	-0.3	0.0	-0.2	-0.4	-1.3	0.2	-0.1	-1.4	-1.3	-0.9	0.3	0.0	-0.1	-0.7
Ever had bowel cancer screening	0.5	0.5	2.4	-0.7	-1.1	-0.0	-0.9	-0.1	-1.0	-1.0	-0.8	-1.6	-0.4	-0.1	-0.5	-0.8	0.8	-0.3	-1.0	-0.7	-0.3	-1.0	-0.9	-0.6	0.4	-0.3	-0.5	0.1
Commuting to job workplace: Walk	0.5	0.5	1.6	1.0	0.9	1.2	0.3	0.8	0.9	0.7	0.8	1.3	0.1	-0.1	0.6	0.6	0.1	0.5	1.1	0.3	1.0	0.6	0.7	0.5	0.1	0.1	0.3	1.1
Asthma (self-reported)	0.5	1.0	6.9	-0.6	-1.1	-1.5	-1.0	1.2	0.7	-0.7	0.2	-1.0	0.7	-0.6	-1.1	-1.2	0.1	-0.3	-0.9	-0.3	-0.2	-0.9	-1.2	-0.8	-0.8	-1.1	0.3	-2.6
Average weekly champagne plus white wine intake	0.5	0.7	2.2	-1.1	-1.0	-0.6	-0.5	0.0	-1.5	-1.0	-0.7	-1.5	-0.4	-0.2	-0.8	-1.1	-0.2	-1.1	-1.1	-0.2	-0.5	-0.9	-0.9	-0.6	-0.6	-0.5	-0.2	-1.2
Irritability	0.5	0.9	4.1	-0.9	-1.6	-0.7	0.4	0.2	-0.8	-2.0	-0.9	-1.6	0.3	-0.9	-0.6	-0.4	-0.3	-1.0	-1.3	0.2	-0.2	-1.3	-1.1	-0.9	-0.7	-0.3	-0.2	-1.4
Risk taking	0.5	0.7	2.5	0.6	1.0	0.6	0.9	-0.9	1.5	1.1	0.4	1.1	-0.4	0.6	0.7	0.7	-1.1	0.9	0.9	0.4	0.0	0.9	1.0	0.5	-0.0	0.4	0.1	1.6
Commuting to job workplace: Cycle	0.5	0.6	1.5	-1.0	-1.1	-0.8	-0.7	-0.4	0.4	-0.8	-0.6	-1.2	0.2	-0.6	-0.8	-0.9	0.5	-0.0	-1.0	-0.2	-0.8	-1.0	-0.9	-0.9	-1.0	-0.6	-0.1	-0.7
Impedance of whole body	0.5	2.4	15.9	2.0	2.0	0.1	0.4	-0.3	4.0	2.5	1.3	2.5	-0.2	0.6	1.2	1.3	0.9	1.6	1.9	0.2	0.4	1.5	1.5	0.8	1.6	0.2	0.3	1.5
Bipolar Disorder (2018)	0.4	0.6	2.9	-1.1	-0.9	-0.4	1.1	0.5	-0.9	-1.7	-0.4	-1.1	0.9	-0.1	-0.4	-0.0	-1.0	-0.3	-1.0	0.9	0.1	-0.6	-0.3	0.0	-0.5	0.6	0.2	0.9
Irritable Bowel Disease (IBD)	0.4	0.9	3.4	-1.3	-1.8	-0.4	-0.2	0.2	-0.9	-1.8	-0.6	-1.8	0.8	-0.2	-1.0	-0.9	0.4	0.4	-1.6	-0.0	-0.3	-1.3	-1.2	-0.6	0.1	-0.2	-0.3	0.0
Mean Putamen Volume	0.4	0.5	1.7	1.1	0.8	1.3	-0.6	-0.9	1.1	1.0	-0.1	0.2	-0.5	0.3	0.7	0.4	1.0	1.2	0.8	-0.0	-0.0	0.6	0.6	0.2	0.4	0.1	-0.0	0.7
Primary Biliary Cirrhosis	0.4	0.5	3.0	1.7	-0.1	0.8	1.2	0.2	0.2	-0.3	0.6	0.0	0.8	0.7	0.5	0.7	1.1	0.7	0.0	0.4	0.9	0.1	0.3	0.6	0.7	0.8	1.0	0.2
Type 2 Diabetes (T2D) (2012)	0.4	0.5	1.6	0.2	0.8	0.9	0.1	-0.0	0.5	1.0	0.5	0.9	0.5	0.7	0.6	0.5	0.7	1.3	0.8	0.4	0.3	0.8	0.7	0.6	1.0	0.5	0.7	0.9
Hearing difficulty/problems: Yes	0.4	0.6	2.3	0.0	1.2	1.3	-0.5	-0.7	0.6	1.5	0.1	1.5	-1.2	0.2	0.5	0.5	-0.6	0.2	1.1	-0.3	-0.3	0.8	0.8	0.2	0.1	-0.2	-0.3	0.2
Systolic blood pressure, automated reading	0.4	1.3	7.7	-0.2	-1.4	0.8	0.4	1.3	-2.8	-2.0	-0.3	-1.9	1.0	0.1	0.7	0.9	0.2	-0.1	-0.7	1.4	1.1	-0.6	-0.8	0.1	1.3	1.5	0.6	-0.8
Angina	0.4	0.5	6.0	0.0	-0.5	0.3	0.8	1.0	-2.5	-1.0	0.1	-0.5	0.5	0.1	-0.1	-0.0	-0.7	-0.3	-0.5	0.6	0.5	-0.2	-0.1	0.3	0.2	0.5	0.3	-0.2
Diabetes (father)	0.4	0.5	2.4	0.1	-0.5	0.4	0.7	1.3	-1.2	-0.8	0.6	-0.6	1.6	0.6	-0.4	-0.6	0.8	0.9	-0.7	0.5	0.7	-0.1	-0.2	0.5	0.2	0.3	0.9	-0.4
Supplements: Glucosamine	0.4	0.6	2.6	-0.3	0.9	-0.0	-0.2	-1.4	0.2	1.1	-0.1	1.6	-1.6	-0.3	-0.4	-0.5	0.2	-0.2	0.5	-1.4	-0.6	0.1	0.6	-0.1	0.0	-1.0	-0.9	0.3
Medication: Levothyroxine sodium	0.4	0.8	1.8	-0.5	1.0	1.4	-0.1	-0.3	-0.4	1.1	0.3	0.9	0.4	1.2	1.2	1.3	-0.6	0.6	0.9	0.7	0.6	1.0	1.0	1.0	1.2	1.3	0.4	0.6
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	2.8	-0.2	-0.0	-0.5	0.9	1.7	-0.3	-0.4	0.8	0.2	1.3	0.2	0.6	1.0	-0.3	0.1	0.2	1.1	0.9	0.2	0.2	0.5	1.0	0.8	0.9	-0.2
Medication: Ramipril	0.4	0.5	2.0	-0.5	-1.1	-0.6	-0.5	0.7	-1.1	-1.4	-0.3	-1.3	0.2	-0.7	-0.3	-0.2	0.3	-0.7	-0.7	0.3	0.3	-1.0	-1.0	-0.6	0.3	-0.1	0.2	-0.6
Neuroticism score	0.4	0.9	3.9	0.6	-0.2	-0.4	1.5	1.5	0.1	-0.7	0.7	-0.6	2.0	0.7	0.5	0.8	1.6	0.5	-0.1	1.3	0.9	0.1	0.4	0.6	1.6	1.0	1.1	-0.9
Worrier / anxious feelings	0.4	0.7	2.6	0.7	-1.0	-0.9	0.2	1.6	-0.6	-1.3	-0.1	-1.5	1.4	-0.0	-0.3	-0.4	1.4	-0.2	-0.9	0.4	0.4	-0.6	-0.5	-0.1	0.9	0.2	0.6	-1.4
Mouth/teeth dental problems: Dentures	0.4	0.6	3.7	0.6	0.5	0.9	1.6	-0.7	-1.9	-0.1	0.1	0.5	-0.4	1.1	0.8	0.8	-0.6	0.2	0.4	0.1	0.8	0.6	0.8	0.9	0.5	1.0	0.4	0.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.3	3.4	0.8	1.2	0.6	1.6	1.3	1.1	0.8	1.0	1.6	0.8	0.5	1.5	1.8	-1.6	0.5	1.2	1.2	0.9	1.1	1.3	1.1	-0.2	1.4	1.1	0.1
Ever highly irritable/argumentative for 2 days	0.4	0.4	5.2	-1.3	-0.2	-0.2	-0.1	-0.3	-1.2	-0.5	-0.2	0.0	-0.2	-0.2	-0.6	-0.4	-2.3	-0.6	-0.5	-0.1	-0.3	-0.2	-0.2	-0.1	-0.8	-0.2	-0.3	-0.6
Comparative body size at age 10	0.4	1.2	5.0	-0.2	-1.0	0.9	1.3	2.2	-1.4	-1.7	0.4	-1.4	2.2	0.6	-0.5	-0.6	1.6	-0.2	-1.1	1.0	0.7	-0.4	-0.3	0.6	-0.4	0.8	1.2	0.9
Number of full brothers	0.4	0.5	2.2	0.1	0.7	-0.8	0.3	0.2	1.5	1.0	1.0	0.7	0.3	0.4	0.5	0.5	0.9	0.8	0.8	0.6	0.4	0.5	0.6	0.3	0.9	0.0	0.3	0.8
Number of children fathered	0.4	0.4	2.1	0.2	0.3	1.1	0.8	0.9	-1.5	-0.1	0.3	0.1	0.4	0.6	0.2	0.0	1.0	-0.4	0.3	0.5	1.0	0.6	0.5	0.8	0.7	0.7	0.4	0.6
Medication: Blood pressure	0.4	0.6	2.2	-0.6	-1.2	-0.7	-1.5	0.1	-1.0	-0.8	-0.6	-1.4	0.3	-0.5	-0.7	-0.8	0.3	-0.1	-1.0	-0.2	-0.6	-0.9	-1.2	-0.9	-0.2	-0.5	-0.3	-1.1
Angina (self-reported)	0.4	0.5	6.0	0.1	-0.5	0.3	0.8	1.2	-2.5	-1.0	0.3	-0.5	0.7	0.2	-0.1	-0.1	-0.4	-0.1	-0.5	0.8	0.6	-0.2	-0.1	0.4	0.3	0.5	0.5	-0.1
Medication: Omeprazole	0.4	0.5	1.9	0.7	0.4	1.4	0.3	0.6	0.2	0.4	0.8	0.4	0.7	0.8	0.3	0.2	1.1	1.0	0.3	0.5	0.6	0.6	0.6	0.7	1.0	0.4	0.6	1.2
Overall health rating	0.4	0.9	3.5	-0.9	-0.5	0.0	1.1	1.4	-1.8	-1.1	0.1	-1.0	1.6	1.0	0.3	0.2	0.7	-0.0	-0.5	1.2	0.9	0.0	0.0	0.7	1.9	1.2	0.9	-0.9
Illnesses of father: Heart disease	0.4	0.6	3.5	-1.0	-0.7	-0.3	-0.1	0.9	-1.7	-0.7	-0.1	-1.2	0.3	-0.1	-0.9	-1.1	-0.8	-0.7	-0.7	-0.1	0.2	-0.4	-0.5	-0.2	-0.8	-0.4	-0.1	-1.9
Illnesses of siblings: Diabetes	0.4	0.5	2.9	-0.8	-0.2	-0.4	0.1	1.0	-1.7	-0.3	0.3	-0.7	0.7	-0.0	0.2	0.3	0.8	-0.9	0.1	0.8	0.6	0.0	-0.1	0.2	1.0	0.5	0.5	-1.2
Mineral and other dietary supplements	0.4	0.5	2.5	0.8	-0.1	-0.4	-0.1	1.4	1.6	0.4	0.7	-0.1	1.5	0.2	0.1	-0.1	1.2	1.2	0.1	0.6	0.2	0.1	-0.0	0.1	-0.3	0.1	1.0	0.4
Ever taken oral contraceptive pill	0.4	0.4	3.1	0.1	0.8	0.5	0.8	0.0	0.9	0.8	0.5	0.5	0.2	1.1	0.3	0.2	-0.1	0.7	0.4	0.1	0.2	0.9	0.8	0.7	0.6	0.4	0.4	1.8
Eye problems/disorders: Glaucoma	0.4	0.4	1.7	0.1	0.4	0.4	0.7	0.5	1.3	0.6	0.7	0.2	0.3	0.7	0.7	0.6	0.3	0.7	0.7	0.7	0.8	0.4	0.5	0.5	0.9	0.5	0.7	1.1
Medication: Paracetamol	0.4	0.7	3.3	-0.6	-1.2	0.4	0.8	0.2	-1.6	-1.8	-0.6	-1.3	0.7	-0.2	0.1	0.4	-1.1	-0.4	-0.9	0.6	0.4	-0.6	-0.7	-0.2	-0.7	0.9	0.2	-0.5
Alcohol drinker status: Never	0.4	0.5	2.9	-0.5	-0.6	-0.1	-0.4	1.5	-0.2	-0.6	0.7	-0.3	1.7	-0.2	-0.0	0.1	1.0	0.6	-0.3	1.1	0.6	-0.6	-0.5	0.0	-0.0	0.2	1.1	-0.4
Age started oral contraceptive pill	0.4	0.5	2.1	-0.2	0.7	-0.4	-1.1	-1.5	0.6	1.1	-0.2	1.0	-1.2	-0.6	0.5	0.4	1.4	0.5	0.7	0.1	-0.6	0.1	0.2	-0.4	0.5	-0.5	-0.6	-0.4
Alcohol drinker status: Previous	0.4	0.5	1.8	-0.5	0.6	-0.1	0.8	1.3	-0.4	0.4	0.9	0.7	0.9	0.8	0.4	0.5	0.5	-0.1	0.6	0.8	1.0	0.5	0.8	0.9	0.9	0.7	0.8	0.1
Neuroticism (Nagel 2018)	0.3	0.7	3.1	0.3	-0.7	-0.9	1.0	1.4	-0.4	-1.1	0.3	-1.1	1.7	0.2	0.1	0.2	1.6	0.2	-0.5	0.8	0.8	-0.3	-0.3	0.1	1.6	0.6	0.7	-0.6
Ulcerative Colitis (UC)	0.3	0.7	1.9	0.2	-0.2	0.8	0.4	1.2	-0.3	-0.5	0.7	-0.3	1.4	1.0	0.3	0.5	1.0	1.3	-0.0	0.7	1.1	0.1	0.2	0.8	1.4	0.9	0.9	1.2
Major Depression (MDD)	0.3	0.4	3.5	0.7	0.3	1.2	0.5	0.6	-0.1	0.1	0.5	0.5	0.6	0.4	-0.3	-0.5	1.9	0.1	0.1	0.2	0.5	0.4	0.2	0.6	0.1	-0.1	0.5	1.0
Neuroticism (2016)	0.3	0.4	1.7	0.4	-0.7	-0.8	-0.6	0.2	0.3	-1.0	-0.6	-0.7	-0.3	-0.4	-0.6	-0.5	1.3	-1.0	-0.5	-0.9	-0.3	-0.8	-0.7	-0.6	0.5	-0.6	-0.2	0.1
Triglycerides	0.3	0.5	1.1	-0.8	-0.8	-0.7	-0.5	-0.8	0.3	-0.6	-0.6	-0.4	-0.4	-0.8	-1.0	-1.0	-0.0	0.0	-0.7	-0.8	-0.5	-0.9	-1.0	-0.8	-0.6	-0.9	-0.7	0.7
Allergy or Eczema	0.3	0.8	4.3	-1.3	-1.1	-2.1	-0.9	1.4	0.4	-1.2	0.1	-0.6	0.8	-1.0	-0.5	-0.3	-0.6	-0.4	-0.9	0.2	-0.1	-1.2	-1.1	-0.7	-0.1	-0.5	-0.0	-0.6
Neuroticism	0.3	0.8	5.2	1.0	-0.5	-0.8	1.0	1.1	-0.1	-0.9	0.3	-1.1	1.5	0.4	0.1	0.3	2.3	0.3	-0.4	0.6	0.6	-0.2	0.0	0.2	1.7	0.6	0.7	-0.7
Sensitivity / hurt feelings	0.3	0.5	2.9	0.6	0.6	0.3	1.1	0.4	0.7	0.4	0.6	0.4	0.8	0.5	0.6	0.7	1.7	0.3	0.5	0.4	0.8	0.5	0.8	0.6	1.5	0.6	0.7	-0.0
Medication for hormone replacement therapy	0.3	0.3	1.1	0.3	-0.5	-0.0	0.8	-0.3	-1.0	-1.0	-0.6	-0.7	-0.3	-0.1	-0.6	-0.7	-0.3	-0.4	-0.8	-0.0	-0.4	-0.3	-0.2	-0.3	-0.5	-0.3	-0.5	0.5
Maternal smoking around birth	0.3	0.5	3.1	1.0	-0.0	1.4	1.1	-0.7	-1.8	-0.7	-0.5	-0.2	-0.3	0.5	0.2	0.2	0.9	-0.2	-0.3	-0.1	0.2	0.3	0.2	0.3	0.7	0.6	0.1	0.7
Fed-up feelings	0.3	0.6	5.5	-0.3	-1.0	-1.4	0.9	0.4	-0.5	-1.1	-0.1	-0.7	0.5	-0.8	-0.2	0.3	0.2	-0.3	-0.7	0.6	-0.2	-0.9	-0.6	-0.7	-0.1	-0.0	0.2	-2.4
Relative age voice broke	0.3	0.5	1.4	0.8	0.4	0.4	0.7	1.0	1.0	0.3	0.6	0.3	0.8	0.7	1.2	1.1	0.2	0.3	0.6	1.0	0.5	0.5	0.4	0.5	0.6	1.1	0.9	-0.3
High blood pressure	0.3	0.8	4.3	0.0	-0.8	-0.0	0.1	2.1	-1.2	-1.0	0.6	-1.3	1.9	0.5	0.1	0.2	0.2	0.8	-0.5	1.7	0.9	-0.1	-0.4	0.3	0.7	0.8	1.0	-0.5
Waist circumference	0.3	1.2	4.8	-1.7	-1.6	-0.6	-0.1	0.9	-1.7	-1.6	-0.5	-1.8	0.5	-1.0	-0.6	-0.6	-0.3	-0.7	-1.0	0.6	-0.1	-1.4	-1.3	-0.9	-0.4	-0.1	-0.2	-2.2
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	2.0	-0.7	0.3	0.8	0.8	0.1	-1.1	0.1	0.1	0.4	0.0	0.6	0.6	0.9	-1.4	-0.2	0.4	0.6	0.5	0.5	0.5	0.4	0.1	0.8	0.3	-1.1
Number of live births	0.3	0.4	1.1	-0.4	-0.6	-0.5	-0.5	-1.0	-0.3	-0.8	-1.0	0.1	-1.1	-0.9	-0.7	-0.3	-0.4	-0.8	-0.6	-0.8	-0.5	-0.7	-0.6	-0.5	-0.6	-0.6	-0.9	-0.6
Asthma	0.3	0.6	4.6	-0.2	-0.8	-1.2	-0.6	1.2	0.8	-0.4	0.4	-0.8	0.8	-0.3	-0.8	-0.9	-0.1	0.0	-0.7	-0.1	0.0	-0.7	-0.9	-0.6	-0.7	-0.9	0.5	-2.1
Impedance of arm (left)	0.3	1.6	14.4	1.6	1.5	-0.7	-0.4	-1.0	3.8	2.1	0.7	2.4	-0.9	-0.3	0.6	0.8	0.4	0.8	1.4	-0.9	-0.3	0.8	0.8	-0.0	0.8	-0.7	-0.3	0.9
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.4	1.6	0.2	0.7	1.3	1.2	-0.4	-0.4	0.2	0.0	0.6	0.2	0.5	0.7	0.9	0.1	0.2	0.6	0.5	0.4	0.7	0.9	0.6	0.7	0.8	0.3	0.1
Age at first live birth	0.3	0.5	4.9	0.3	0.9	-0.3	-0.1	0.1	2.2	1.3	0.6	1.2	-0.2	-0.2	0.3	0.3	0.4	0.1	0.8	-0.3	-0.3	0.5	0.6	-0.0	-0.3	-0.4	0.1	-0.4
Medication: Ibuprofen	0.3	0.4	2.3	-0.6	-0.6	-1.2	-0.1	-0.3	-0.5	-0.9	-0.5	-0.6	0.0	-0.4	-0.5	-0.5	-1.5	-0.0	-0.7	-0.3	-0.4	-0.6	-0.6	-0.4	-0.8	-0.4	-0.3	0.2
Had major operations	0.3	0.3	2.6	-0.1	0.2	0.0	0.5	-0.8	-1.2	0.3	0.0	0.2	-0.5	0.4	0.5	0.7	-1.6	0.6	0.4	0.4	0.1	0.2	0.3	0.2	0.2	0.5	-0.3	-0.2
Hypertension (Self-reported)	0.3	0.7	3.6	0.1	-0.8	-0.1	-0.0	1.9	-1.0	-0.9	0.6	-1.1	1.8	0.4	0.1	0.2	0.3	1.0	-0.4	1.7	0.9	-0.2	-0.5	0.2	0.7	0.7	0.9	-0.7
Medication: Aspirin	0.3	0.4	2.6	-0.5	-0.2	0.3	-0.2	-1.1	-1.6	-0.5	-0.8	-0.4	-0.8	0.2	-0.5	-0.6	-0.9	-0.7	-0.6	-0.5	-0.5	-0.1	-0.1	-0.2	0.3	-0.2	-0.8	0.5
High cholesterol (Self-reported)	0.3	0.5	2.8	0.2	-0.7	0.6	-0.5	-0.4	-1.7	-0.8	-0.9	-0.9	-0.3	-0.4	-0.8	-0.7	0.9	-0.8	-0.7	-0.9	-0.3	-0.6	-0.5	-0.4	0.4	-0.4	-0.5	-0.6
Ever had prostate specific antigen (PSA) test	0.3	0.4	1.1	-0.2	-0.8	-0.4	-0.5	0.4	-1.0	-0.8	-0.3	-1.0	0.2	-0.2	-0.7	-0.7	-0.4	-1.0	-0.8	-0.8	-0.1	-0.6	-0.6	-0.4	-0.4	-0.4	-0.1	-0.5
Vascular/heart problems diagnosed by doctor	0.3	0.9	4.8	0.4	1.3	0.4	0.3	-1.6	2.2	1.4	-0.1	1.7	-1.4	-0.1	0.4	0.3	0.1	-0.2	1.0	-1.4	-0.4	0.6	0.9	0.2	-0.4	-0.4	-0.4	0.9
Cholesterol lowering medication	0.3	0.4	3.3	0.7	0.1	1.0	0.0	-0.2	-1.8	-0.6	-0.6	0.1	-0.5	0.1	0.2	0.4	1.4	-0.6	-0.0	0.1	0.2	0.3	0.3	0.3	1.3	0.6	-0.2	-0.0
Heart disease (siblings)	0.3	0.3	1.2	0.3	-0.6	-0.5	0.5	0.8	-1.1	-1.0	0.1	-0.6	0.8	-0.2	-0.3	-0.1	-0.8	-0.5	-0.5	0.2	0.6	-0.3	-0.4	-0.0	-0.4	0.0	0.3	-0.9
Breast Cancer	0.2	0.6	2.9	-0.8	-0.8	0.2	-0.5	0.5	-1.7	-0.8	-0.1	-0.7	0.3	-0.2	-0.5	-0.4	-1.6	-0.3	-0.7	-0.1	-0.3	-0.3	-0.8	-0.2	-1.4	-0.0	0.1	-1.3
Hypothyroidism (self reported)	0.2	0.5	3.9	-0.6	0.5	1.0	-0.6	-1.0	-1.1	0.8	-0.1	0.4	-0.6	0.7	0.1	-0.1	-2.0	-0.0	0.4	-0.6	0.2	0.4	0.4	0.5	-0.8	0.1	-0.3	-0.0
Relative age of first facial hair	0.2	0.5	3.5	-0.6	-0.6	-1.3	0.0	-0.0	1.3	-0.2	-0.2	-0.1	-0.3	-0.6	-0.0	0.0	-1.1	-0.3	-0.3	-0.4	-0.7	-0.5	-0.6	-0.8	-0.9	-0.4	0.1	-1.9
Ever had hysterectomy (womb removed)	0.2	0.3	0.8	0.2	-0.7	-0.9	0.0	-0.5	-0.2	-0.6	-0.6	-0.8	-0.2	-0.4	-0.5	-0.5	0.8	0.0	-0.6	-0.5	-0.4	-0.6	-0.5	-0.7	-0.1	-0.5	-0.4	-0.3
Supplements: Zinc	0.2	0.2	0.7	-0.7	-0.6	-0.6	-0.2	-0.4	0.5	-0.6	-0.1	0.2	-0.3	-0.5	-0.3	0.0	-0.6	0.4	-0.5	0.1	-0.2	-0.8	-0.6	-0.4	-0.3	-0.3	-0.3	0.4
Sitting height	0.2	1.6	6.4	-0.9	-1.1	0.4	0.1	-0.3	-1.4	-1.3	-1.2	-1.0	-0.8	-1.3	-0.8	-0.6	-2.5	-2.2	-1.2	-0.5	-1.0	-1.0	-0.9	-1.0	-2.4	-0.4	-0.8	-2.0
Forced vital capacity (FVC)	0.2	0.7	3.3	0.5	1.3	0.3	0.8	-0.1	1.0	1.2	0.3	1.4	-0.5	0.0	0.7	0.8	-1.8	0.1	1.0	-0.1	0.1	0.9	1.1	0.6	-1.1	0.4	0.1	-0.0
Alcohol intake versus 10 years previously	0.2	0.3	1.5	-0.1	-0.5	-0.8	0.3	0.7	-1.2	-0.9	0.0	-0.7	0.9	-0.1	-0.2	-0.1	-0.4	-0.1	-0.7	0.7	0.2	-0.4	-0.3	0.0	-0.0	0.3	0.4	-1.1
Hair/balding pattern: Pattern 4	0.2	0.4	2.5	0.1	0.8	-0.1	-0.8	-0.6	1.6	1.4	0.4	0.7	-0.5	-0.2	-0.2	-0.2	1.0	0.5	0.9	-0.5	-0.1	0.2	0.5	-0.1	0.0	-0.8	-0.3	0.3
Comparative height size at age 10	0.2	1.2	6.4	-1.8	-0.5	-0.6	-0.7	-0.6	-1.8	-0.3	-0.8	-1.0	-1.2	-0.8	-0.8	-0.7	-2.5	-1.6	-0.4	-0.9	-0.7	-0.5	-0.5	-0.7	-0.8	-0.6	-1.3	-1.6
Suffer from ‘nerves’	0.2	0.4	1.8	0.5	0.2	0.3	0.8	0.8	-0.3	-0.5	0.6	0.3	1.4	0.2	0.1	0.5	0.2	0.4	0.0	0.7	1.0	0.3	0.4	0.7	1.0	0.7	0.5	0.1
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.5	3.1	-0.2	-0.3	0.3	1.2	1.8	0.1	-0.3	0.6	-0.3	1.3	-0.2	0.2	0.4	-0.4	-0.7	-0.1	0.9	0.6	0.0	-0.0	0.2	-0.5	0.5	0.7	-1.5
Medication for cholesterol	0.2	0.2	1.2	-0.2	0.0	-0.2	0.4	0.9	1.1	0.3	0.8	0.1	0.7	0.2	0.2	-0.0	-0.5	0.3	0.3	-0.3	0.6	0.0	-0.1	0.2	-0.6	-0.1	0.9	-0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.2	1.1	0.4	-0.1	0.5	0.1	0.8	-0.5	-0.4	0.4	-0.4	1.0	0.6	0.2	-0.1	-0.3	0.0	-0.1	0.8	0.8	0.2	0.1	0.5	0.0	0.5	0.5	0.1
Miserableness	0.2	0.3	1.2	-0.0	-0.1	-0.1	0.8	0.8	0.1	-0.4	0.5	-0.1	0.8	0.2	0.3	0.5	1.1	0.4	0.2	0.9	0.7	0.0	0.1	0.3	1.0	0.5	0.6	-0.6
Medication: Bendroflumethiazide	0.2	0.3	1.6	0.5	-0.3	-0.1	-1.3	-0.2	0.5	0.1	-0.0	-0.4	-0.1	-0.6	0.4	0.4	0.9	0.8	0.1	0.2	-0.4	-0.5	-0.6	-0.8	0.1	-0.3	-0.2	-1.0
Medication: Omeprazole (e.g. Zanprol)	0.2	0.3	1.9	0.4	0.4	1.4	0.1	0.5	0.5	0.4	0.5	0.5	0.4	0.4	0.2	0.1	0.8	0.6	0.3	0.3	0.4	0.5	0.4	0.4	0.6	0.1	0.4	0.9
Basal cell carcinoma (self-reported)	0.2	0.3	2.1	0.9	-0.5	-0.0	-0.1	0.9	1.4	-0.6	0.4	-0.3	0.7	-0.4	0.1	0.1	0.4	0.4	-0.1	0.1	0.3	-0.4	-0.5	-0.4	-0.4	-0.2	0.6	0.2
Coronary Artery Disease (CAD)	0.1	0.1	1.0	0.1	0.5	-0.3	-1.0	-0.2	0.2	0.3	-0.1	0.1	-0.7	-0.7	0.2	0.3	-0.5	-0.1	0.3	-0.0	-0.3	0.4	0.2	-0.4	-0.2	-0.3	-0.3	0.0
LDL Cholesterol	0.1	0.2	0.8	0.5	-0.7	-0.0	-0.2	-0.1	-0.6	-0.9	-0.8	-0.5	-0.2	-0.3	-0.4	-0.5	0.2	-0.7	-0.7	-0.2	-0.1	-0.6	-0.6	-0.3	-0.5	-0.2	-0.2	-0.7
Ulcerative Colitis	0.1	0.2	1.0	-0.7	-0.4	-1.0	-0.3	0.9	-0.7	-0.4	0.4	-0.2	0.6	0.2	-0.4	-0.2	0.6	0.3	-0.3	-0.4	0.2	-0.2	-0.2	0.0	0.4	-0.2	0.3	-0.3
Blood Red Count	0.1	0.8	3.5	1.2	0.2	1.0	1.3	1.9	-0.7	-0.0	0.9	0.5	1.2	0.1	1.0	1.3	0.8	-0.4	0.6	0.7	1.2	0.5	0.6	0.7	0.5	1.2	1.1	0.0
Height	0.1	2.3	21.8	-0.9	-0.6	0.4	1.8	1.3	-2.9	-1.0	-0.1	-0.5	0.4	-0.4	-0.1	0.2	-4.7	-1.8	-0.6	0.6	0.1	-0.2	0.1	0.0	-2.4	0.6	0.1	-3.0
Cardiovascular Disease	0.1	0.5	1.9	0.3	-1.0	-0.0	0.0	1.4	-0.5	-1.2	0.1	-1.2	1.2	-0.3	-0.1	0.1	0.1	0.2	-0.5	1.0	0.9	-0.6	-0.7	-0.1	0.5	0.4	0.5	-0.7
Tanning	0.1	0.8	2.2	0.8	1.1	-0.0	1.5	0.4	0.4	1.1	1.1	1.3	0.5	1.4	0.2	0.1	-1.1	0.7	0.7	0.1	0.5	1.1	1.2	1.2	-0.6	0.4	0.9	1.1
Bilateral oophorectomy (both ovaries removed)	0.1	0.1	0.8	0.5	-0.5	-0.1	-0.1	0.5	-0.9	-0.7	-0.0	-0.4	0.2	0.1	-0.2	-0.1	0.3	-0.2	-0.4	-0.1	0.3	-0.3	-0.4	-0.1	-0.4	-0.1	0.4	0.2
Hearing difficulty/problems with background noise	0.1	0.2	2.0	0.1	0.3	0.4	-0.6	-1.1	0.2	0.6	-0.3	0.3	-1.4	0.3	0.1	0.1	-0.1	0.2	0.3	-0.5	-0.4	0.2	0.1	-0.2	0.5	-0.3	-0.5	0.4
Falls in the last year	0.1	0.1	0.7	0.1	-0.3	-0.8	-0.1	0.1	-0.1	-0.4	-0.1	-0.2	0.4	-0.2	-0.5	-0.5	-0.7	-0.5	-0.5	-0.3	-0.2	-0.4	-0.2	-0.3	-0.1	-0.4	-0.1	-0.0
Hair/balding pattern: Pattern 3	0.1	0.1	0.5	-0.3	0.2	0.1	-0.3	-0.5	-0.5	0.3	-0.0	0.3	-0.4	0.2	-0.3	-0.4	-0.1	-0.7	-0.0	-0.4	-0.1	0.4	0.1	0.2	0.6	-0.2	-0.5	-0.3
Forced expiratory volume in 1-second (FEV1)	0.1	0.4	1.3	0.3	0.8	0.2	1.1	0.9	0.6	0.5	0.5	1.0	0.5	0.1	0.7	0.9	-1.0	0.4	0.6	0.7	0.3	0.6	0.9	0.7	-0.5	0.8	0.5	-0.1
Medication: Ibuprofen (e.g. Nurofen)	0.1	0.2	1.6	-0.3	-0.3	-0.5	0.3	-0.2	-0.5	-0.8	-0.4	-0.4	0.2	-0.2	-0.0	-0.0	-1.3	-0.2	-0.4	-0.0	-0.1	-0.3	-0.3	-0.1	-0.6	0.1	-0.2	0.5
Standing height	0.1	1.0	9.9	-0.8	-0.4	0.1	1.4	1.3	-1.0	-0.8	-0.1	-0.4	0.7	-0.4	-0.0	0.2	-3.1	-1.5	-0.5	0.5	0.1	-0.2	0.0	-0.0	-1.4	0.5	0.1	-2.0
Peak expiratory flow (PEF)	0.1	0.3	1.0	-0.5	-0.7	-0.4	0.8	0.9	-0.2	-1.0	-0.3	-0.4	0.9	-0.4	-0.1	0.2	-0.6	0.4	-0.8	0.4	-0.3	-0.5	-0.3	-0.1	-0.5	0.5	-0.0	0.3
Gout (self-reported)	0.1	0.1	0.7	0.8	-0.3	-0.2	0.6	0.5	-0.1	-0.6	0.1	0.2	0.4	-0.2	0.0	0.2	-0.1	0.3	-0.3	0.8	-0.1	-0.3	-0.1	-0.0	0.1	0.2	0.4	-0.6
Medication: Ventolin 100micrograms inhaler	0.1	0.2	1.9	0.3	-0.0	0.3	-0.5	0.7	1.4	0.3	0.5	0.1	0.5	0.2	-0.0	-0.0	0.0	0.3	0.1	0.1	0.3	0.1	-0.2	-0.0	-0.2	-0.2	0.5	-0.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.1	0.2	0.8	-0.1	0.1	0.5	0.9	0.3	0.1	-0.4	0.2	0.2	0.5	0.3	0.3	0.5	-0.3	-0.1	0.1	0.6	0.6	0.2	0.3	0.4	0.7	0.5	0.4	0.3
Supplements: Vitamin C	0.1	0.1	0.4	-0.0	0.5	-0.0	0.4	-0.6	-0.1	0.6	0.1	0.2	-0.6	0.4	0.1	0.1	-0.2	0.4	0.3	0.2	0.0	0.2	0.5	0.1	0.3	-0.1	-0.1	-0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.3	2.1	0.5	0.5	-0.3	-0.4	-0.4	1.4	0.6	-0.2	0.6	-0.5	-0.7	0.2	0.3	-0.2	0.0	0.4	-0.4	-0.5	0.1	0.2	-0.3	-0.9	-0.2	-0.3	0.3
Medication: Blood pressure	0.1	0.2	1.3	0.1	-0.2	0.2	-0.3	0.7	-0.9	-0.3	0.1	-0.3	0.6	0.3	0.3	0.5	0.5	0.3	-0.0	1.1	0.3	-0.0	-0.0	0.1	0.7	0.7	0.2	-0.1
HDL Cholesterol	0.0	0.0	0.4	0.3	0.0	-0.1	0.2	0.2	0.3	0.2	-0.1	-0.7	-0.3	0.4	0.2	0.0	0.0	-0.2	-0.0	0.1	-0.1	0.1	0.1	0.1	0.2	0.2	-0.1	0.1
Hair Pigment	0.0	1.1	4.1	0.6	1.4	1.7	0.3	-1.1	0.5	1.5	0.3	1.5	-1.7	0.9	0.8	0.6	0.3	1.0	1.2	-0.5	0.2	1.2	1.1	0.7	0.8	0.2	0.0	2.0
Medication: Amlodipine	0.0	0.1	0.2	0.2	0.2	-0.2	0.0	0.1	-0.3	0.1	0.2	0.4	0.5	0.4	0.0	0.0	0.4	0.3	-0.1	0.2	-0.2	0.3	0.2	0.2	0.4	0.2	-0.0	0.1
Wheeze or whistling in the chest in last year	0.0	0.0	0.2	-0.3	-0.2	-0.1	0.3	-0.0	-0.2	-0.3	0.1	-0.1	-0.0	-0.1	-0.2	-0.0	-0.3	0.2	-0.1	-0.1	0.2	0.0	0.0	-0.0	0.2	-0.1	-0.1	-0.5

Hub : Genes

CYP2D8P1

Models

Trait associations