TWAS hub - CYTL1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Breast Invasive Carcinoma	0.0468	0.0176	6.0e-06	0.035	0.025	0.029	NA	0.030	7.8e-08	6.3e-06	9.6e-07	NA	6.3e-07
2	TCGA	Prostate Adenocarcinoma	0.1089	0.0369	1.1e-05	0.078	0.063	0.065	NA	0.064	1.6e-08	3.9e-07	2.4e-07	NA	2.7e-07

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Peak expiratory flow (PEF)	13.0	30.1	36.8	6.1	-4.8
Waist Hip Ratio (WHR)	6.0	27.2	53.7	0.8	7.3
Medication: Omeprazole	5.7	6.8	13.5	3.7	-0.3
Height	3.7	72.0	144.0	-0.2	12.0
Medication: Omeprazole (e.g. Zanprol)	3.6	4.4	8.6	2.9	-0.4
Body Mass Index (BMI) (2010)	3.4	4.6	5.9	-1.8	-2.4
Lung cancer (father)	3.4	3.9	7.8	0.1	2.8
Lung FVC	3.3	16.9	30.4	1.9	-5.5
Shortness of breath walking on level ground	3.1	3.7	5.1	-1.5	2.3
Stomach or abdominal pain in last month	3.0	3.7	3.8	1.9	-1.9
Alcohol drinker status: Never	3.0	3.6	5.1	-2.3	1.5
Standing height	2.6	26.0	51.7	0.5	7.2
Commuting to job workplace: Cycle	2.6	3.1	3.8	-1.9	-1.6
Number of incorrect matches in round	2.4	4.0	8.0	0.1	2.8
Medication: Cholesterol lowering	2.4	3.8	5.1	-1.6	-2.3
Number of children fathered	2.4	2.7	5.3	-2.3	0.3
Mouth/teeth dental problems: Mouth ulcers	2.4	3.8	6.8	-2.6	0.9
Medication: Aspirin	2.4	3.1	6.1	0.2	-2.5
Crohns Disease (2012)	2.3	3.7	7.5	0.0	-2.7
Glaucoma (self-reported)	2.3	2.8	5.4	2.3	0.3
Eye problems/disorders: None of the above	2.3	2.6	4.5	-2.1	-0.9
Alcohol intake versus 10 years previously	2.2	3.3	4.7	-2.2	1.4
Medication: Aspirin	2.2	2.9	5.8	0.4	-2.4
Mood swings	2.2	3.9	4.5	-1.8	-2.1
Migraine (self-reported)	2.0	2.5	5.0	2.2	0.3
Forced expiratory volume in 1-second (FEV1), predicted	2.0	4.2	7.9	0.7	2.8
Impedance of leg (right)	1.9	9.1	15.4	1.7	3.9
Mouth/teeth dental problems	1.9	3.0	4.4	2.1	-1.2
Hair/balding pattern: Pattern 3	1.9	2.8	5.1	2.3	-0.7
Comparative body size at age 10	1.9	5.2	6.9	-2.6	-1.9
BMI	1.8	10.6	21.0	-0.4	-4.6
Diverticular disease/diverticulitis (self-reported)	1.8	2.1	2.3	1.4	1.5
Illnesses of siblings: Diabetes	1.8	2.2	4.1	-2.0	0.5
Falls in the last year	1.7	2.3	4.5	0.1	2.1
Mouth/teeth dental problems: Dentures	1.7	2.8	5.4	-2.3	0.5
Birth weight	1.7	3.8	7.5	0.2	-2.7
Comparative height size at age 10	1.7	9.5	17.6	1.2	4.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.7	3.6	4.1	1.7	-2.0
Depressed Affect (Nagel 2018)	1.6	3.5	5.4	-2.3	-1.2
Prostate Cancer	1.6	2.3	4.1	-2.0	0.7
Medication: Co-codamol	1.6	1.8	3.6	-0.2	1.9
Townsend deprivation index at recruitment	1.6	2.3	4.4	0.4	-2.1
Medication: Paracetamol	1.6	2.6	4.5	2.1	-0.8
Age at first live birth	1.6	2.9	4.2	-1.3	2.0
Supplements: Vitamin C	1.6	1.9	2.7	1.1	-1.6
Ever had stillbirth, spontaneous miscarriage or termination	1.6	1.7	3.0	0.7	1.7
Breast cancer (self-reported)	1.6	1.9	3.0	-0.9	1.7
Unable to work because of sickness or disability	1.6	2.0	4.0	0.3	-2.0
Rheumatoid Arthritis	1.5	2.0	3.5	-0.8	1.9
Ever used hormone-replacement therapy (HRT)	1.5	1.9	3.8	1.9	0.0
High blood pressure (mother)	1.5	2.1	3.6	-1.9	-0.8
Impedance of leg (left)	1.5	7.2	13.7	0.9	3.7
Illnesses of mother	1.5	1.9	3.6	1.9	-0.5
Mineral and other dietary supplements	1.5	2.0	3.8	0.4	-2.0
Supplements: Fish oil (including cod liver oil)	1.5	1.9	3.8	-0.3	1.9
LDL Cholesterol	1.4	2.2	4.2	2.1	0.4
Relative age of first facial hair	1.4	2.8	2.9	-1.7	-1.6
Body mass index (BMI)	1.4	6.1	11.8	-0.6	-3.4
Had menopause	1.4	1.8	2.2	1.5	1.2
Age at last live birth	1.4	2.0	4.0	0.0	2.0
HDL Cholesterol	1.3	2.2	2.4	1.4	-1.6
Past tobacco smoking	1.3	2.4	4.6	2.1	0.3
Hair/balding pattern: Pattern 2	1.3	1.7	2.6	-0.9	1.6
Handedness (chirality/laterality): Left-handed	1.3	1.6	2.4	-1.6	0.9
Miserableness	1.3	2.2	2.4	-1.6	-1.4
Pain type(s) experienced in last month: Hip pain	1.3	1.6	1.8	1.2	-1.4
Smoking Status	1.2	2.8	3.9	-2.0	-1.3
Impedance of arm (right)	1.2	5.6	9.4	1.3	3.1
Mouth/teeth dental problems: Bleeding gums	1.2	1.6	1.7	1.2	1.3
Alcohol intake frequency.	1.2	2.9	3.7	-1.5	1.9
Qualifications: NVQ or HND or HNC or equivalent	1.2	1.5	2.2	-0.9	-1.5
Back pain experienced in last month	1.2	1.8	1.9	1.4	-1.3
Eye problems/disorders: Glaucoma	1.2	1.4	2.3	1.5	0.7
Medication: Paracetamol	1.2	1.9	3.4	1.9	-0.5
Pain experienced in last month	1.2	2.1	4.0	-2.0	0.3
Number of treatments/medications taken	1.1	2.0	3.5	1.9	-0.6
Serious illness, injury or assault of a close relative in last 2 years	1.1	1.3	1.9	1.4	-0.8
Medication for cholesterol, blood pressure or diabetes	1.1	1.8	3.5	0.2	1.9
Emphysema/chronic bronchitis	1.1	1.3	1.7	0.9	-1.3
Medication for pain relief, constipation, heartburn	1.1	1.9	3.1	-0.8	1.8
Chest pain or discomfort	1.1	1.6	3.1	0.0	1.8
Illnesses of father: Heart disease	1.1	1.5	3.1	1.8	-0.0
Ever had bowel cancer screening	1.1	1.3	2.5	1.6	-0.3
Commuting to job workplace: Walk	1.1	1.2	1.4	-1.0	-1.2
Wears glasses or contact lenses	1.1	1.3	2.4	1.5	-0.5
High cholesterol (Self-reported)	1.1	1.9	2.5	-1.1	-1.6
Medication: Atorvastatin	1.1	1.3	2.3	-1.5	-0.6
Ever smoked	1.1	1.9	3.9	-2.0	-0.1
Impedance of whole body	1.1	5.7	10.0	1.2	3.2
Reaction Time	1.0	1.9	2.7	-1.6	1.0
Heel T-Score	1.0	8.1	14.9	3.9	1.1
Hypothyroidism (self reported)	1.0	2.2	4.2	0.5	-2.1
Average weekly spirits intake	1.0	1.2	1.6	0.9	1.3
Ever had hysterectomy (womb removed)	1.0	1.1	2.2	1.5	-0.1
Vitamin and mineral supplements	1.0	1.3	2.3	-1.5	-0.5
Relative age voice broke	1.0	1.5	2.2	-0.9	-1.5
Frequency of tenseness / restlessness in last 2 weeks	1.0	1.6	2.0	-1.1	-1.4
Had other major operations	1.0	1.2	2.1	-1.5	0.6
Fluid intelligence score	1.0	2.0	3.7	0.6	-1.9
Frequency of tiredness / lethargy in last 2 weeks	1.0	1.6	2.6	-1.6	-0.8
Heart disease (mother)	1.0	1.3	1.8	-0.9	1.3
Smoking status: Previous	1.0	1.5	2.8	-1.7	-0.4
Hearing aid user	1.0	1.1	2.3	-1.5	0.0
Medication: Bendroflumethiazide	1.0	1.5	2.9	1.7	-0.0
Supplements: Calcium	1.0	1.1	1.7	0.8	1.3
Heart attack/myocardial infarction (self-reported)	1.0	1.4	2.2	-1.5	-0.7
Heart disease (siblings)	1.0	1.3	1.5	-1.2	-1.0
Alzheimer’s Disease (including proxy)	0.9	1.3	1.8	1.3	-0.9
Ulcerative Colitis (UC)	0.9	1.8	3.3	1.8	-0.4
Hayfever, allergic rhinitis or eczema	0.9	2.0	2.9	-1.1	-1.7
Heart attack	0.9	1.1	1.8	-1.4	-0.7
Long-standing illness, disability or infirmity	0.9	1.4	2.4	1.5	-0.6
Lupus	0.8	1.2	1.4	1.0	-1.2
Hearing difficulty/problems: Yes	0.8	1.3	2.3	0.5	1.5
Other serious medical condition/disability diagnosed by doctor	0.8	1.0	1.3	1.1	-0.8
Diabetes (father)	0.8	1.0	2.0	-1.4	0.1
Serious illness, injury or assault to yourself	0.8	0.9	1.4	-0.7	-1.2
Alcohol usually taken with meals	0.8	1.3	2.4	0.4	1.6
Hip circumference	0.8	3.3	6.5	0.1	-2.5
Father’s age at death	0.8	1.1	2.1	0.2	-1.4
Impedance of arm (left)	0.8	3.6	6.3	1.0	2.5
Exposure to tobacco smoke at home	0.8	0.9	1.9	1.4	-0.0
Hair/balding pattern: Pattern 4	0.8	1.9	3.8	-2.0	-0.2
High blood pressure (siblings)	0.8	1.1	1.4	1.2	-0.9
Medication: Seretide 50 evohaler	0.8	0.9	1.8	1.3	-0.2
Knee pain experienced in last month	0.8	1.2	2.4	0.2	1.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.8	0.9	1.6	1.3	0.4
Age started oral contraceptive pill	0.8	1.0	2.0	0.2	1.4
Bipolar Disorder (2018)	0.7	1.1	1.2	-1.0	-1.1
Alzheimer’s Disease (in mother)	0.7	0.8	1.6	1.2	-0.4
Age at First Birth	0.7	1.0	1.2	-0.9	-1.1
HbA1C	0.7	0.7	0.9	0.7	1.0
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	0.9	1.8	-0.1	1.3
Heel bone mineral density (BMD) T-score, automated (left)	0.7	1.6	3.0	-0.5	1.7
Multivitamins +/- minerals	0.7	0.9	1.7	1.3	0.3
Financial difficulties in last 2 years	0.7	0.9	1.3	-1.1	0.7
Hayfever/allergic rhinitis (self-reported)	0.7	0.9	1.6	-1.3	-0.5
Medication: Simvastatin	0.7	1.0	1.5	-0.8	-1.2
Neuroticism score	0.7	1.5	2.0	-1.0	-1.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.7	2.3	3.1	1.8	-1.2
Breastfed as a baby	0.7	0.9	1.7	0.3	-1.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.7	1.1	1.2	1.0	-1.1
Chronic bronchitis/emphysema (mother)	0.7	0.9	1.4	-1.2	-0.6
Mouth/teeth dental problems: Loose teeth	0.7	0.9	1.0	0.8	-1.0
Leg pain on walking	0.7	0.8	1.6	0.3	-1.3
Arm fat percentage (left)	0.7	2.8	5.5	-0.3	-2.3
Irritability	0.7	1.2	1.4	-1.2	-1.0
Cardiovascular Disease	0.6	1.9	3.7	0.1	-1.9
Fed-up feelings	0.6	1.1	2.1	-1.4	-0.4
Age when periods started (menarche)	0.6	1.4	2.1	-0.8	1.5
Medication: Levothyroxine sodium	0.6	1.1	1.3	0.9	-1.1
Hearing difficulty/problems with background noise	0.6	0.9	1.7	1.3	0.4
Arm fat percentage (right)	0.6	2.2	4.4	-0.3	-2.1
Qualifications: A levels/AS levels or equivalent	0.6	1.3	1.5	-1.2	1.0
Hypothyroidism/myxoedema (self-reported)	0.6	1.3	2.1	0.7	-1.4
Forced vital capacity (FVC), Best measure	0.6	2.2	3.8	1.9	-0.8
Neck or shoulder pain in last month	0.6	0.9	1.1	1.1	-0.8
Mean time to correctly identify matches	0.6	1.1	1.4	-0.9	1.2
Illness, injury, bereavement, stress in last 2 years	0.6	0.7	1.2	1.1	0.5
Average weekly red wine intake	0.6	0.8	1.7	-0.1	1.3
Osteoporosis (self-reported)	0.6	0.8	0.8	0.9	0.9
Average weekly champagne plus white wine intake	0.6	0.8	1.0	-0.7	-1.0
Mother’s age at death	0.6	0.8	0.8	-0.9	0.9
Commuting to job workplace: Public transport	0.6	0.7	0.9	0.7	-0.9
Neuroticism (Nagel 2018)	0.5	1.2	1.5	-1.2	-1.0
Neuroticism	0.5	1.2	2.3	-1.5	-0.4
Hand grip strength (left)	0.5	1.3	1.5	-1.2	-1.1
Hand grip strength (right)	0.5	1.3	2.1	-1.5	-0.7
Qualifications: CSEs or equivalent	0.5	0.7	1.2	-1.1	-0.4
Allergy	0.5	1.1	2.1	0.4	1.5
Trunk fat-free mass	0.5	2.8	5.2	-0.5	2.3
Happiness	0.5	0.6	1.2	-1.1	-0.3
Prospective memory result	0.5	0.6	1.1	0.5	-1.0
Trunk predicted mass	0.5	2.7	5.2	-0.5	2.3
Length of working week for main job	0.5	0.6	1.0	1.0	-0.4
Pulse wave reflection index	0.5	0.6	1.1	-0.4	1.0
Ever highly irritable/argumentative for 2 days	0.5	0.6	0.9	-0.9	-0.6
Gout (self-reported)	0.5	0.7	1.3	-0.3	-1.2
Leg fat percentage (right)	0.5	1.7	3.3	0.4	-1.8
Exposure to tobacco smoke outside home	0.5	0.7	1.0	1.0	0.6
Number of full brothers	0.5	0.7	1.2	1.1	0.3
Qualifications: College or University degree	0.5	1.6	3.1	-1.7	0.3
Suffer from ‘nerves’	0.5	0.8	1.1	0.7	-1.1
Eye problems/disorders: Cataract	0.5	0.6	1.1	-0.4	1.0
Tinnitus: Yes, now most or all of the time	0.5	0.6	1.1	-0.2	1.0
Risk taking	0.5	0.7	1.2	0.3	1.1
Ever had prostate specific antigen (PSA) test	0.5	0.6	1.0	-0.5	-1.0
Schizophrenia vs Biploar Disorder	0.4	0.5	1.1	0.0	1.0
Alzheimer’s Disease (in father)	0.4	0.4	0.7	0.8	-0.4
Irritable Bowel Disease (IBD)	0.4	1.0	1.8	1.3	-0.4
Major Depression (MDD)	0.4	0.5	1.0	-1.0	0.3
Pack years adult smoking proportion	0.4	0.6	1.1	1.1	0.2
Maternal smoking around birth	0.4	0.6	1.0	1.0	0.3
Supplements: Glucosamine	0.4	0.5	1.1	1.0	-0.0
Illnesses of siblings	0.4	0.5	0.7	-0.5	0.8
Pulse wave Arterial Stiffness index	0.4	0.5	0.7	-0.8	0.5
Headache pain in last month	0.4	0.7	1.0	-1.0	-0.5
Medication: Ventolin 100micrograms inhaler	0.4	0.6	1.1	1.1	0.1
Pulse wave peak to peak time	0.4	0.4	0.9	0.9	0.0
Medication: Allopurinol	0.4	0.6	1.0	0.4	-1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.4	0.8	-0.9	0.3
Number of self-reported non-cancer illnesses	0.4	0.8	1.2	1.1	-0.6
Illnesses of father: High blood pressure	0.4	0.5	0.9	-0.4	1.0
Leg fat percentage (left)	0.4	1.5	3.0	-0.1	-1.7
Bipolar Disorder or Schizophrenia	0.3	0.6	1.3	-0.1	-1.1
Verbal and Numeric Reasoning (VNR)	0.3	0.7	1.3	-0.0	-1.2
Triglycerides	0.3	0.4	0.8	-0.2	0.9
Lung FEV1/FVC ratio	0.3	1.7	2.5	1.6	-1.0
Eye problems/disorders: Diabetes related eye disease	0.3	0.4	0.7	0.0	0.9
Medication for hormone replacement therapy	0.3	0.4	0.7	0.1	0.9
Supplements: Zinc	0.3	0.3	0.6	-0.8	-0.2
Bilateral oophorectomy (both ovaries removed)	0.3	0.4	0.6	-0.8	-0.3
Pain all over the body in last month	0.3	0.3	0.6	0.7	-0.2
Time employed in main current job	0.3	0.3	0.6	-0.8	0.2
Worrier / anxious feelings	0.3	0.6	1.1	-0.3	-1.0
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.4	0.6	0.4	-0.7
Medication: Lansoprazole	0.3	0.4	0.8	-0.9	0.1
Body fat percentage	0.3	1.2	2.4	0.2	-1.6
Wheeze or whistling in the chest in last year	0.3	0.5	0.8	0.9	0.3
Pulse rate, automated reading	0.3	0.9	1.1	0.8	1.1
Loneliness, isolation	0.3	0.4	0.8	-0.1	-0.9
Qualifications: nursing, teaching	0.3	0.5	0.7	0.8	-0.5
Arm fat mass (left)	0.3	1.2	2.1	-0.4	-1.5
Diastolic blood pressure, automated reading	0.3	0.9	1.2	0.8	1.1
Myopia	0.3	0.4	0.8	-0.1	-0.9
Alcohol drinker status: Previous	0.3	0.3	0.4	-0.6	0.4
Pack years of smoking	0.3	0.4	0.8	0.9	-0.1
Intelligence (Savage-Jansen 2018)	0.2	0.7	1.2	0.4	-1.1
Schizophrenia (2018)	0.2	0.3	0.4	0.6	-0.6
Mean Putamen Volume	0.2	0.2	0.4	0.6	-0.1
Blood Red Count	0.2	2.3	2.6	-1.4	1.6
Allergy or Eczema	0.2	0.6	1.1	-0.3	-1.1
Frequency of depressed mood in last 2 weeks	0.2	0.2	0.3	-0.5	-0.4
Systolic blood pressure, automated reading	0.2	0.7	1.4	0.1	1.2
Diabetes (mother)	0.2	0.3	0.3	-0.6	-0.5
Current tobacco smoking	0.2	0.4	0.5	0.7	0.5
Medication: Atenolol	0.2	0.2	0.4	-0.2	0.6
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.4	0.7	0.3	0.9
Ever unenthusiastic/disinterested for a whole week	0.2	0.2	0.3	-0.5	0.3
Diabetes (self-reported)	0.2	0.3	0.5	-0.2	-0.7
Medication: Ramipril	0.2	0.3	0.3	-0.4	0.6
Forced expiratory volume in 1-second (FEV1)	0.2	0.7	0.8	0.9	-0.7
Arm fat mass (right)	0.2	0.8	1.3	-0.5	-1.1
Birth weight of first child	0.2	0.3	0.5	0.7	0.2
Loud music exposure frequency	0.2	0.2	0.3	-0.3	0.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.3	0.3	0.6	0.5
Health satisfaction	0.2	0.3	0.4	0.4	-0.6
Medication: Ibuprofen	0.2	0.2	0.3	0.3	-0.6
Leg fat mass (right)	0.2	0.9	1.7	0.0	-1.3
Arm predicted mass (right)	0.2	0.8	1.2	-0.6	1.1
Number of full sisters	0.2	0.3	0.5	0.7	-0.1
Had major operations	0.2	0.3	0.4	0.7	-0.4
Family relationship satisfaction	0.2	0.2	0.4	-0.1	0.6
Whole body fat-free mass	0.2	1.2	2.2	-0.6	1.5
Illnesses of father: None of the above (group 1)	0.2	0.2	0.5	-0.7	-0.1
Smoking status: Current	0.2	0.3	0.6	0.8	0.2
Whole body water mass	0.2	1.1	2.0	-0.5	1.4
Financial situation satisfaction	0.2	0.3	0.5	0.7	-0.1
Medication: Lisinopril	0.2	0.3	0.5	-0.7	-0.4
Ever depressed for a whole week	0.2	0.2	0.2	-0.5	0.5
Basal cell carcinoma (self-reported)	0.2	0.2	0.4	-0.6	0.1
Leg fat mass (left)	0.2	0.7	1.3	-0.1	-1.2
Worry (Nagel 2018)	0.1	0.2	0.3	-0.3	-0.6
Crohns Disease (2017)	0.1	0.3	0.5	0.0	-0.7
Ovarian Cancer	0.1	0.2	0.3	0.5	-0.1
Fasting Glucose	0.1	0.1	0.2	-0.4	0.2
Ulcerative Colitis	0.1	0.1	0.3	-0.1	0.5
Systolic Blood Pressure	0.1	0.4	0.8	-0.2	0.9
Respiratory disease	0.1	0.3	0.6	0.8	0.2
Type 2 Diabetes (T2D) (2018)	0.1	0.1	0.2	-0.4	-0.4
Chronotype (morning person)	0.1	0.3	0.3	0.5	-0.5
Hair Pigment	0.1	2.4	4.4	-0.6	2.1
Tanning	0.1	1.3	1.5	-1.0	-1.2
Sensitivity / hurt feelings	0.1	0.1	0.2	-0.2	-0.4
Angina	0.1	0.1	0.2	-0.2	0.5
Medication: Metformin	0.1	0.1	0.1	0.1	0.4
Trunk fat percentage	0.1	0.5	0.9	0.4	-1.0
Average weekly fortified wine intake	0.1	0.1	0.1	0.3	0.2
Taking other prescription medications	0.1	0.2	0.3	0.3	-0.5
Waist circumference	0.1	0.5	0.9	0.3	0.9
Forced vital capacity (FVC)	0.1	0.4	0.8	0.9	0.2
Qualifications: None of the above	0.1	0.2	0.4	0.3	0.6
Number of live births	0.1	0.2	0.2	0.5	-0.4
Pulse rate	0.1	0.2	0.3	0.2	0.6
Noisy workplace	0.1	0.1	0.2	0.4	0.2
Asthma	0.1	0.2	0.3	-0.2	0.6
Depression (self-reported)	0.1	0.1	0.3	0.0	0.5
Tense / ‘highly strung’	0.1	0.2	0.3	0.4	-0.6
Qualifications: O levels/GCSEs or equivalent	0.1	0.1	0.2	0.1	0.5
Arm fat-free mass (right)	0.1	0.6	1.0	-0.5	1.0
Medication: Blood pressure	0.1	0.1	0.2	-0.4	-0.2
Angina (self-reported)	0.1	0.1	0.2	0.2	0.5
Whole body fat mass	0.1	0.4	0.7	0.0	-0.8
Overall health rating	0.1	0.3	0.5	-0.7	-0.3
Hypertension (Self-reported)	0.1	0.2	0.3	-0.3	0.5
Diabetes diagnosed by doctor	0.1	0.1	0.2	-0.4	-0.1
Medication for cholesterol	0.1	0.2	0.2	0.5	-0.3
Asthma (self-reported)	0.1	0.1	0.2	-0.3	0.4
Guilty feelings	0.1	0.1	0.2	-0.2	-0.5
Ever taken oral contraceptive pill	0.1	0.1	0.1	0.4	0.2
Medication: Blood pressure	0.1	0.1	0.2	0.3	0.4
Basal metabolic rate	0.1	0.7	1.1	-0.6	1.1
Arm fat-free mass (left)	0.1	0.7	1.1	-0.5	1.0
Number of operations (self-reported)	0.1	0.2	0.4	0.2	-0.6
Average weekly beer plus cider intake	0.1	0.2	0.2	-0.3	-0.5
Fractured/broken bones in last 5 years	0.1	0.1	0.1	-0.4	0.2
Arm predicted mass (left)	0.1	0.6	1.0	-0.4	1.0
Depression (Nagel 2018)	0.0	0.0	0.0	0.1	0.1
Breast Cancer	0.0	0.1	0.2	0.1	0.4
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0
Neuroticism (2016)	0.0	0.0	0.1	0.1	0.2
Primary Biliary Cirrhosis	0.0	0.0	0.0	0.0	-0.0
Schizophrenia (2014)	0.0	0.0	0.0	-0.0	0.1
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.1	0.0	0.3
Blood Eosinophil Count	0.0	0.2	0.3	0.5	0.2
Blood Platelet Count	0.0	0.3	0.5	-0.3	0.7
Blood White Count	0.0	0.1	0.1	0.3	0.2
Severe depression (siblings)	0.0	0.0	0.0	0.0	0.0
Leg fat-free mass (left)	0.0	0.0	0.0	-0.1	0.1
Tinnitus: Yes, but not now, but have in the past	0.0	0.0	0.0	0.2	0.2
High blood pressure	0.0	0.1	0.2	-0.5	0.2
Sitting height	0.0	0.3	0.6	0.8	0.1
Chronic bronchitis/emphysema (father)	0.0	0.1	0.1	-0.0	0.3
Leg predicted mass (left)	0.0	0.0	0.0	-0.1	0.0
Trunk fat mass	0.0	0.1	0.1	0.1	-0.3
Nervous feelings	0.0	0.1	0.1	-0.1	-0.4
Weight	0.0	0.0	0.0	-0.2	-0.0
Blood clot in the leg (DVT)	0.0	0.0	0.0	-0.0	0.1
Medication: Amlodipine	0.0	0.0	0.0	-0.1	0.1
Worry too long after embarrassment	0.0	0.1	0.1	0.2	-0.2
Reason for reducing amount of alcohol drunk: Health precaution	0.0	0.0	0.1	-0.3	0.1
Commuting to job workplace: Car/motor vehicle	0.0	0.0	0.1	0.1	0.3
Leg fat-free mass (right)	0.0	0.1	0.3	-0.5	0.0
Friendships satisfaction	0.0	0.0	0.0	0.0	-0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.0	0.1	0.1	0.3	-0.0
Osteoarthritis (self-reported)	0.0	0.0	0.1	0.3	0.1
Medication: Gliclazide	0.0	0.0	0.0	0.0	0.1
Leg predicted mass (right)	0.0	0.1	0.3	-0.5	0.0
Vascular/heart problems diagnosed by doctor	0.0	0.1	0.2	0.4	0.1
Cholesterol lowering medication	0.0	0.0	0.1	-0.1	-0.3
Deep venous thrombosis (DVT) (self-reported)	0.0	0.0	0.0	-0.1	-0.0

Hub : Genes

CYTL1

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Trait associations