TWAS hub - DAGLA

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Nerve Tibial	0.132	0.0469	0.00580	0.071	NA	0.021	NA	0.056	1.0e-05	NA	0.01100	NA	7.6e-05
2	GTEx	Testis	0.255	0.0710	0.00014	0.157	NA	0.087	NA	0.010	1.9e-07	NA	0.00011	NA	1.2e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Headache pain in last month	11.4	19.5	20.3	-4.3	-4.5
Illness, injury, bereavement, stress in last 2 years	9.8	12.0	13.7	3.7	3.2
Schizophrenia vs Biploar Disorder	8.7	11.5	12.6	-3.5	-3.2
Ever depressed for a whole week	7.5	9.3	12.0	3.5	2.6
Pulse rate	6.9	11.7	11.8	3.4	3.4
Major Depression (MDD)	6.8	8.3	8.5	2.9	2.8
Wheeze or whistling in the chest in last year	6.4	11.3	11.6	-3.3	-3.4
Blood Red Count	6.3	60.5	65.1	8.1	7.5
Hearing aid user	6.2	7.0	9.3	-3.0	-2.2
Fasting Glucose	6.1	7.3	8.5	-2.9	-2.5
Qualifications: NVQ or HND or HNC or equivalent	5.8	6.9	8.2	-2.9	-2.4
Triglycerides	5.4	8.9	9.4	2.9	3.1
Pulse rate, automated reading	5.2	16.8	18.8	3.8	4.3
Family relationship satisfaction	5.1	6.2	6.5	2.4	2.5
Knee pain experienced in last month	5.1	7.9	9.6	-3.1	-2.5
Medication: Lisinopril	4.9	6.3	7.4	2.7	2.3
Fractured/broken bones in last 5 years	4.8	6.2	7.8	-2.1	-2.8
Blood Eosinophil Count	4.7	36.5	38.6	-6.2	-5.9
Ulcerative Colitis	4.5	6.5	7.3	2.7	2.4
Age started oral contraceptive pill	4.5	5.7	6.2	2.2	2.5
Irritable Bowel Disease (IBD)	4.2	9.9	10.2	3.2	3.1
Myopia	4.1	6.0	7.0	2.7	2.2
Blood White Count	4.0	29.6	29.7	-5.4	-5.5
Breastfed as a baby	4.0	4.9	8.5	2.9	1.1
Ulcerative Colitis (UC)	3.8	7.0	8.6	2.9	2.3
Pain experienced in last month	3.8	6.3	7.3	2.7	2.3
Neuroticism (Nagel 2018)	3.7	8.7	9.1	3.0	2.9
Blood Platelet Count	3.6	42.2	49.3	5.9	7.0
Hypothyroidism (self reported)	3.6	8.4	9.5	-2.7	-3.1
Neuroticism	3.6	8.6	9.3	3.0	2.8
Irritability	3.6	6.1	7.0	2.6	2.3
Emphysema/chronic bronchitis	3.5	4.0	5.0	-1.7	-2.2
Neuroticism (2016)	3.4	5.0	6.1	2.0	2.5
Type 2 Diabetes (T2D) (2012)	3.3	3.8	4.1	-1.9	-2.0
Worrier / anxious feelings	3.3	6.2	7.2	2.3	2.7
Seen doctor (GP) for nerves, anxiety, tension or depression	3.2	5.0	6.6	2.6	1.8
Body Mass Index (BMI) (2010)	3.1	4.3	4.4	-2.1	-2.0
Neuroticism score	3.1	6.4	7.9	2.8	2.2
Bipolar Disorder (2018)	3.0	4.7	7.3	2.7	1.5
Fluid intelligence score	2.9	6.0	8.5	2.9	1.9
Glaucoma (self-reported)	2.8	3.2	4.2	-2.0	-1.5
Fed-up feelings	2.7	5.0	6.5	1.9	2.5
Falls in the last year	2.7	3.7	3.8	-1.9	-1.9
Asthma (self-reported)	2.7	5.5	6.3	-2.1	-2.5
Crohns Disease (2017)	2.6	5.7	6.6	2.2	2.6
Systolic blood pressure, automated reading	2.6	7.6	8.0	2.7	2.8
Medication: Levothyroxine sodium	2.6	4.4	5.4	-2.3	-1.8
Asthma	2.6	5.1	5.9	-2.1	-2.4
Overall health rating	2.6	5.5	5.7	-2.4	-2.3
Osteoarthritis (self-reported)	2.6	3.4	4.5	-2.1	-1.5
Basal cell carcinoma (self-reported)	2.6	3.1	3.4	-1.8	-1.7
Depressed Affect (Nagel 2018)	2.5	5.3	6.4	2.5	2.1
Allergy	2.5	5.7	8.1	1.8	2.9
Depression (self-reported)	2.5	3.0	3.2	1.8	1.6
Tense / ‘highly strung’	2.5	4.2	4.9	2.2	1.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.5	3.0	3.4	1.6	1.8
Relative age voice broke	2.4	3.7	4.6	2.1	1.7
Medication for cholesterol, blood pressure or diabetes	2.4	4.0	4.6	-1.8	-2.1
Eye problems/disorders: None of the above	2.4	2.7	3.7	1.9	1.3
Ever unenthusiastic/disinterested for a whole week	2.3	2.8	3.8	1.9	1.3
Comparative body size at age 10	2.3	6.2	6.3	-2.5	-2.5
HbA1C	2.2	2.4	2.9	-1.4	-1.7
Hair/balding pattern: Pattern 4	2.2	5.4	5.9	-2.4	-2.2
Respiratory disease	2.1	4.7	5.1	-2.1	-2.3
Eye problems/disorders: Glaucoma	2.1	2.4	3.6	-1.9	-1.1
Ever had prostate specific antigen (PSA) test	2.1	2.4	2.7	1.4	1.6
Number of incorrect matches in round	2.0	3.3	3.7	1.7	1.9
Serious illness, injury or assault of a close relative in last 2 years	2.0	2.3	2.3	-1.5	-1.5
Medication: Cholesterol lowering	2.0	3.2	4.4	1.4	2.1
Exposure to tobacco smoke at home	2.0	2.3	2.4	-1.4	-1.6
Bipolar Disorder or Schizophrenia	1.9	4.6	7.3	2.7	1.4
HDL Cholesterol	1.9	3.2	3.9	-2.0	-1.6
Serious illness, injury or assault to yourself	1.9	2.3	2.9	-1.7	-1.3
Illnesses of father: None of the above (group 1)	1.9	2.4	2.6	1.5	1.6
Miserableness	1.9	3.3	4.4	2.1	1.5
Supplements: Calcium	1.9	2.1	2.6	1.6	1.3
Impedance of leg (left)	1.8	8.6	9.3	2.8	3.1
Had major operations	1.8	2.1	2.9	1.7	1.1
Age at First Birth	1.7	2.4	4.1	2.0	0.8
Health satisfaction	1.7	2.2	2.3	-1.5	-1.5
Guilty feelings	1.7	2.6	3.0	1.7	1.5
Worry (Nagel 2018)	1.6	3.4	3.8	1.9	1.7
LDL Cholesterol	1.6	2.5	3.7	-1.9	-1.2
Qualifications: A levels/AS levels or equivalent	1.6	3.4	5.3	-1.3	-2.3
Blood clot in the leg (DVT)	1.6	2.1	3.1	-1.8	-1.0
Exposure to tobacco smoke outside home	1.6	2.1	2.9	-1.7	-1.1
Medication: Blood pressure	1.6	2.8	3.5	1.9	1.5
Smoking status: Current	1.6	2.5	4.2	-2.1	-0.8
Reaction Time	1.5	2.8	3.1	-1.8	-1.6
Alcohol intake versus 10 years previously	1.5	2.2	2.9	1.2	1.7
Number of live births	1.5	2.1	2.1	-1.4	-1.4
Systolic Blood Pressure	1.4	7.1	8.9	3.0	2.3
Impedance of leg (right)	1.4	6.8	6.8	2.6	2.6
Current tobacco smoking	1.4	2.3	4.0	-2.0	-0.8
Hayfever/allergic rhinitis (self-reported)	1.4	1.8	2.0	-1.3	-1.4
Average weekly champagne plus white wine intake	1.4	1.9	2.7	1.6	1.1
Intelligence (Savage-Jansen 2018)	1.3	4.0	5.4	2.3	1.6
Frequency of depressed mood in last 2 weeks	1.3	1.8	2.3	1.5	1.1
Other serious medical condition/disability diagnosed by doctor	1.3	1.7	1.7	-1.3	-1.3
Severe depression (siblings)	1.3	1.5	2.2	-0.9	-1.5
Leg fat-free mass (left)	1.3	6.7	7.8	-2.4	-2.8
Frequency of tenseness / restlessness in last 2 weeks	1.3	2.0	3.2	1.8	0.9
Illnesses of siblings	1.3	1.9	2.4	-1.2	-1.5
High blood pressure (siblings)	1.3	1.8	1.9	1.4	1.3
Medication for pain relief, constipation, heartburn	1.3	2.2	3.9	2.0	0.7
Suffer from ‘nerves’	1.3	2.0	2.6	1.2	1.6
Leg fat-free mass (right)	1.3	7.2	8.0	-2.5	-2.8
Leg predicted mass (right)	1.3	7.1	7.8	-2.5	-2.8
Wears glasses or contact lenses	1.3	1.5	1.6	1.3	1.2
Mother’s age at death	1.3	1.6	1.8	1.2	1.3
Unable to work because of sickness or disability	1.3	1.7	2.7	-1.6	-0.8
Taking other prescription medications	1.2	1.9	3.3	-1.8	-0.7
Leg predicted mass (left)	1.2	6.4	7.4	-2.3	-2.7
Alcohol usually taken with meals	1.2	2.0	3.2	1.8	0.8
Seen a psychiatrist for nerves, anxiety, tension or depression	1.2	1.5	2.8	1.7	0.6
Supplements: Fish oil (including cod liver oil)	1.2	1.6	2.5	-1.6	-0.9
Verbal and Numeric Reasoning (VNR)	1.1	2.5	4.3	2.1	0.9
Ovarian Cancer	1.1	1.5	2.2	-1.5	-0.8
Crohns Disease (2012)	1.1	1.7	1.9	1.2	1.4
Primary Biliary Cirrhosis	1.1	1.6	1.9	-1.1	-1.4
Relative age of first facial hair	1.1	2.3	2.3	1.5	1.5
Nervous feelings	1.1	2.0	3.0	1.7	1.0
Had menopause	1.1	1.4	1.7	1.3	1.0
Qualifications: None of the above	1.1	2.4	4.6	0.4	2.1
Financial difficulties in last 2 years	1.1	1.5	1.6	-1.3	-1.2
Medication: Ventolin 100micrograms inhaler	1.1	1.4	1.5	1.2	1.1
Age at last live birth	1.1	1.6	2.5	-0.8	-1.6
Forced expiratory volume in 1-second (FEV1), predicted	1.1	2.2	2.4	-1.6	-1.4
Long-standing illness, disability or infirmity	1.1	1.7	2.8	-1.7	-0.8
Heel T-Score	1.0	7.6	8.9	2.5	3.0
Sensitivity / hurt feelings	1.0	1.7	2.1	1.4	1.2
Frequency of unenthusiasm / disinterest in last 2 weeks	1.0	1.4	2.1	0.8	1.4
Qualifications: CSEs or equivalent	1.0	1.4	1.4	-1.1	-1.2
Medication: Atenolol	1.0	1.2	1.3	1.1	1.1
Heel bone mineral density (BMD) T-score, automated (right)	1.0	2.3	2.4	1.5	1.6
Heart attack	1.0	1.2	1.5	-1.2	-1.0
Trunk fat-free mass	1.0	5.5	7.2	-2.0	-2.7
Time employed in main current job	1.0	1.2	1.2	1.1	1.0
Father’s age at death	1.0	1.4	1.9	1.4	0.9
Medication: Paracetamol	1.0	1.6	2.5	-1.6	-0.9
Qualifications: College or University degree	1.0	3.2	6.1	-0.5	-2.5
Whole body fat-free mass	1.0	5.8	7.2	-2.1	-2.7
Friendships satisfaction	1.0	1.2	1.7	1.3	0.8
Whole body water mass	1.0	5.5	6.8	-2.1	-2.6
Basal metabolic rate	1.0	5.5	6.7	-2.0	-2.6
Heart attack/myocardial infarction (self-reported)	1.0	1.3	1.5	-1.2	-1.0
Rheumatoid Arthritis	0.9	1.2	1.4	-1.0	-1.2
Ever used hormone-replacement therapy (HRT)	0.9	1.2	1.3	1.0	1.2
Medication for hormone replacement therapy	0.9	1.0	1.2	-0.8	-1.1
Supplements: Glucosamine	0.9	1.2	1.5	-1.2	-0.9
Forced expiratory volume in 1-second (FEV1)	0.9	2.9	3.8	-1.4	-1.9
Trunk predicted mass	0.9	5.2	7.0	-1.9	-2.6
Hypothyroidism/myxoedema (self-reported)	0.9	1.8	1.9	-1.3	-1.4
Shortness of breath walking on level ground	0.9	1.1	1.4	-1.2	-0.9
Illnesses of father: High blood pressure	0.9	1.1	1.2	-1.1	-1.0
Number of operations (self-reported)	0.9	1.4	1.8	1.3	1.0
Cholesterol lowering medication	0.9	1.3	2.1	-1.4	-0.7
BMI	0.8	4.4	5.3	-1.8	-2.3
Mouth/teeth dental problems: Dentures	0.8	1.4	2.0	-1.4	-0.9
Illnesses of mother	0.8	1.0	1.3	-0.8	-1.1
Length of working week for main job	0.8	0.9	1.0	-0.9	-1.0
Ever highly irritable/argumentative for 2 days	0.8	0.9	1.1	0.9	1.0
Number of full sisters	0.8	1.0	1.4	0.8	1.2
Medication: Atorvastatin	0.8	1.0	1.3	0.8	1.1
Deep venous thrombosis (DVT) (self-reported)	0.8	1.1	1.9	-1.4	-0.5
Impedance of whole body	0.8	4.2	5.1	1.8	2.3
Schizophrenia (2014)	0.7	1.5	2.8	1.7	0.5
Allergy or Eczema	0.7	1.8	2.8	-0.9	-1.7
Lung FEV1/FVC ratio	0.7	3.3	3.9	-1.7	-2.0
Townsend deprivation index at recruitment	0.7	1.0	1.0	1.0	1.0
Happiness	0.7	0.9	1.0	0.9	1.0
Number of children fathered	0.7	0.7	0.8	0.8	0.9
Smoking status: Previous	0.7	1.0	1.2	0.9	1.1
Breast cancer (self-reported)	0.7	0.8	1.5	0.4	1.2
Tinnitus: Yes, now most or all of the time	0.7	0.8	1.5	-1.2	0.2
Medication: Paracetamol	0.7	1.1	1.9	-1.4	-0.4
Alcohol drinker status: Never	0.7	0.9	1.3	-1.1	-0.7
Depression (Nagel 2018)	0.6	0.9	1.1	1.0	0.9
Supplements: Zinc	0.6	0.6	0.8	0.9	0.7
Tinnitus: Yes, but not now, but have in the past	0.6	0.6	1.1	0.2	-1.1
Impedance of arm (right)	0.6	2.8	3.6	1.4	1.9
Hair/balding pattern: Pattern 3	0.6	0.9	1.1	1.0	0.8
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	2.0	3.0	-1.0	-1.7
Pulse wave Arterial Stiffness index	0.6	0.7	1.0	0.6	1.0
Impedance of arm (left)	0.6	2.6	3.7	1.3	1.9
Birth weight of first child	0.6	1.0	1.0	1.0	1.0
Pulse wave reflection index	0.6	0.8	1.2	-1.1	-0.6
Arm predicted mass (right)	0.6	2.9	3.6	-1.4	-1.9
Illnesses of father: Heart disease	0.6	0.9	1.3	-0.7	-1.1
Ever had bowel cancer screening	0.6	0.7	0.8	-0.9	-0.8
Qualifications: nursing, teaching	0.6	1.0	1.9	-0.2	-1.4
Medication: Gliclazide	0.6	0.7	1.1	0.5	1.0
Schizophrenia (2018)	0.5	1.0	1.6	1.3	0.6
Coronary Artery Disease (CAD)	0.5	0.5	1.0	0.3	1.0
Eye problems/disorders: Diabetes related eye disease	0.5	0.5	0.7	0.9	0.6
Bilateral oophorectomy (both ovaries removed)	0.5	0.5	0.8	0.5	0.9
Diverticular disease/diverticulitis (self-reported)	0.5	0.6	1.0	0.5	1.0
Chronic bronchitis/emphysema (father)	0.5	0.6	0.7	-0.9	-0.6
Mouth/teeth dental problems	0.5	0.8	1.0	0.8	1.0
Medication: Ramipril	0.5	0.7	0.9	0.6	0.9
Prospective memory result	0.5	0.6	1.2	-1.1	-0.3
Qualifications: O levels/GCSEs or equivalent	0.5	0.7	1.5	-0.1	-1.2
Arm fat-free mass (right)	0.5	2.6	3.4	-1.3	-1.8
Pulse wave peak to peak time	0.5	0.5	0.9	-0.4	-0.9
Medication: Omeprazole	0.5	0.5	0.8	0.5	0.9
Commuting to job workplace: Walk	0.5	0.5	0.8	0.5	0.9
Diastolic blood pressure, automated reading	0.5	1.6	2.1	1.0	1.4
Heart disease (siblings)	0.5	0.6	0.8	0.5	0.9
Breast Cancer	0.4	0.9	1.4	-1.2	-0.6
Cardiovascular Disease	0.4	1.3	1.9	0.8	1.4
Number of treatments/medications taken	0.4	0.6	0.7	-0.8	0.8
Hayfever, allergic rhinitis or eczema	0.4	1.0	1.6	-0.6	-1.3
Stomach or abdominal pain in last month	0.4	0.5	0.6	-0.7	-0.8
Hearing difficulty/problems with background noise	0.4	0.7	1.1	0.6	1.0
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	0.7	-0.8	-0.5
Peak expiratory flow (PEF)	0.4	0.9	1.1	1.1	0.9
Medication for cholesterol	0.4	0.6	0.7	0.8	0.8
Mineral and other dietary supplements	0.4	0.6	0.8	0.9	0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.9	1.2	-1.1	-0.7
Ever taken oral contraceptive pill	0.4	0.5	0.7	-0.5	-0.8
High cholesterol (Self-reported)	0.4	0.6	1.2	0.1	1.1
Arm predicted mass (left)	0.4	1.9	2.8	-1.0	-1.7
Alzheimer’s Disease (in father)	0.3	0.4	0.6	-0.4	-0.8
Mean Putamen Volume	0.3	0.3	0.5	0.7	0.4
Lupus	0.3	0.5	0.9	0.4	-0.9
Waist Hip Ratio (WHR)	0.3	1.3	1.4	1.1	1.2
Type 2 Diabetes (T2D) (2018)	0.3	0.5	0.8	-0.9	-0.4
Angina	0.3	0.4	0.7	0.3	0.8
Medication: Metformin	0.3	0.4	0.8	-0.9	-0.0
Age when periods started (menarche)	0.3	0.8	0.9	0.9	0.9
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.6	1.0	0.5	1.0
Forced vital capacity (FVC)	0.3	1.0	1.5	-0.8	-1.2
Diabetes (self-reported)	0.3	0.5	1.0	0.0	1.0
Medication: Simvastatin	0.3	0.5	1.0	-0.0	1.0
Weight	0.3	1.7	2.0	-1.2	-1.4
Noisy workplace	0.3	0.3	0.5	-0.7	-0.4
Mouth/teeth dental problems: Bleeding gums	0.3	0.3	0.5	0.4	-0.7
Forced vital capacity (FVC), Best measure	0.3	0.9	1.3	-0.7	-1.2
Medication: Aspirin	0.3	0.4	0.8	-0.1	0.9
Supplements: Vitamin C	0.3	0.4	0.6	0.7	0.4
Hypertension (Self-reported)	0.3	0.9	0.9	1.0	0.9
Mood swings	0.3	0.6	0.7	0.8	0.7
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	0.5	-0.4	-0.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.3	0.6	-0.8	0.3
Osteoporosis (self-reported)	0.3	0.3	0.7	0.1	-0.8
Medication: Aspirin	0.3	0.4	0.9	-0.0	0.9
Arm fat-free mass (left)	0.3	1.5	2.2	-0.9	-1.5
Commuting to job workplace: Cycle	0.3	0.4	0.7	-0.1	0.8
Alcohol drinker status: Previous	0.3	0.3	0.4	0.6	0.4
Smoking Status	0.2	0.5	1.0	-1.0	0.2
Hearing difficulty/problems: Yes	0.2	0.3	0.6	-0.8	-0.1
Ever had hysterectomy (womb removed)	0.2	0.2	0.3	0.4	0.5
Vitamin and mineral supplements	0.2	0.2	0.2	0.4	0.5
Average weekly fortified wine intake	0.2	0.2	0.4	0.6	-0.2
High blood pressure	0.2	0.7	0.7	0.8	0.8
Multivitamins +/- minerals	0.2	0.2	0.3	-0.3	-0.6
Body mass index (BMI)	0.2	0.9	1.1	-0.9	-1.1
Had other major operations	0.2	0.2	0.3	0.6	0.4
Hip circumference	0.2	1.0	1.1	-1.1	-0.9
Medication: Lansoprazole	0.2	0.2	0.3	-0.6	-0.3
Loud music exposure frequency	0.2	0.2	0.4	0.3	0.6
Chronic bronchitis/emphysema (mother)	0.2	0.2	0.4	-0.6	0.1
Number of full brothers	0.2	0.3	0.3	-0.6	-0.4
Angina (self-reported)	0.2	0.3	0.6	0.2	0.8
Medication: Ibuprofen	0.2	0.3	0.5	-0.7	-0.0
Mean time to correctly identify matches	0.2	0.4	0.5	-0.7	-0.4
Heart disease (mother)	0.2	0.2	0.4	-0.0	0.6
Alcohol intake frequency.	0.2	0.4	0.8	-0.9	0.0
Leg pain on walking	0.2	0.2	0.4	0.2	0.6
Average weekly red wine intake	0.2	0.2	0.3	0.4	-0.6
Diabetes diagnosed by doctor	0.2	0.3	0.6	-0.3	0.8
Back pain experienced in last month	0.2	0.3	0.6	-0.8	0.0
Number of self-reported non-cancer illnesses	0.2	0.3	0.6	-0.8	0.1
Pain type(s) experienced in last month: Hip pain	0.2	0.2	0.4	-0.6	-0.4
Average weekly beer plus cider intake	0.2	0.3	0.3	-0.6	-0.5
Vascular/heart problems diagnosed by doctor	0.2	0.5	0.7	-0.5	-0.8
Alzheimer’s Disease (in mother)	0.1	0.1	0.1	0.4	0.0
Alzheimer’s Disease (including proxy)	0.1	0.1	0.1	-0.2	-0.4
Chronotype (morning person)	0.1	0.2	0.3	0.6	0.4
Hair Pigment	0.1	1.7	2.4	1.0	1.5
Tanning	0.1	1.4	2.0	-0.8	-1.4
Hand grip strength (left)	0.1	0.2	0.2	0.4	-0.4
Average weekly spirits intake	0.1	0.1	0.1	-0.1	-0.4
Medication: Co-codamol	0.1	0.1	0.1	-0.1	-0.3
Pack years adult smoking proportion	0.1	0.2	0.4	-0.6	-0.3
Trunk fat percentage	0.1	0.3	0.5	0.4	0.7
Hand grip strength (right)	0.1	0.3	0.4	0.4	-0.7
Maternal smoking around birth	0.1	0.2	0.3	-0.3	0.6
High blood pressure (mother)	0.1	0.2	0.3	-0.3	-0.5
Waist circumference	0.1	0.4	0.5	-0.7	-0.6
Past tobacco smoking	0.1	0.2	0.5	-0.2	-0.7
Pain all over the body in last month	0.1	0.1	0.2	0.1	0.5
Arm fat mass (right)	0.1	0.5	0.7	-0.6	-0.8
Standing height	0.1	0.6	1.0	-0.5	-1.0
Gout (self-reported)	0.1	0.1	0.3	0.0	0.5
Medication: Amlodipine	0.1	0.2	0.3	-0.3	-0.6
Worry too long after embarrassment	0.1	0.2	0.4	0.6	-0.1
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.1	0.2	-0.2	-0.4
Age at first live birth	0.1	0.2	0.5	-0.1	-0.7
Mouth/teeth dental problems: Loose teeth	0.1	0.2	0.2	-0.5	0.4
Neck or shoulder pain in last month	0.1	0.1	0.1	-0.4	-0.3
Migraine (self-reported)	0.1	0.1	0.1	0.4	-0.1
Medication: Allopurinol	0.1	0.1	0.1	-0.2	0.3
Whole body fat mass	0.1	0.6	0.6	-0.8	-0.8
Leg fat mass (right)	0.1	0.5	0.7	-0.5	-0.9
Chest pain or discomfort	0.1	0.1	0.2	0.1	-0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.1	0.2	0.4	0.4
Illnesses of siblings: Diabetes	0.1	0.1	0.2	0.0	0.5
Arm fat percentage (left)	0.1	0.3	0.3	-0.6	-0.5
Mouth/teeth dental problems: Mouth ulcers	0.1	0.1	0.3	0.5	-0.0
Arm fat mass (left)	0.1	0.6	0.8	-0.6	-0.9
Medication: Bendroflumethiazide	0.1	0.1	0.1	0.3	0.3
Leg fat percentage (left)	0.1	0.3	0.4	0.6	0.6
Risk taking	0.1	0.2	0.2	0.3	-0.5
Leg fat mass (left)	0.1	0.3	0.4	-0.3	-0.6
Prostate Cancer	0.0	0.0	0.0	0.2	-0.2
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0
Height	0.0	0.2	0.2	-0.4	-0.5
Lung FVC	0.0	0.0	0.1	0.0	0.3
Diabetes (father)	0.0	0.0	0.1	-0.3	-0.0
Diabetes (mother)	0.0	0.0	0.0	-0.1	0.0
Sitting height	0.0	0.2	0.3	-0.5	-0.2
Trunk fat mass	0.0	0.1	0.1	-0.3	-0.2
Hair/balding pattern: Pattern 2	0.0	0.0	0.0	0.0	0.0
Arm fat percentage (right)	0.0	0.1	0.1	-0.3	-0.2
Frequency of tiredness / lethargy in last 2 weeks	0.0	0.1	0.1	-0.2	0.3
Lung cancer (father)	0.0	0.0	0.0	-0.1	-0.2
Birth weight	0.0	0.0	0.1	0.3	0.0
Body fat percentage	0.0	0.0	0.1	0.0	0.2
Leg fat percentage (right)	0.0	0.1	0.2	0.4	0.3
Medication: Seretide 50 evohaler	0.0	0.0	0.0	0.1	0.0
Comparative height size at age 10	0.0	0.2	0.3	-0.4	-0.6
Commuting to job workplace: Car/motor vehicle	0.0	0.0	0.0	0.0	-0.0
Handedness (chirality/laterality): Left-handed	0.0	0.0	0.0	0.1	0.1
Loneliness, isolation	0.0	0.0	0.0	0.2	0.2
Eye problems/disorders: Cataract	0.0	0.0	0.0	-0.2	0.2
Financial situation satisfaction	0.0	0.1	0.1	-0.3	0.1
Commuting to job workplace: Public transport	0.0	0.1	0.1	0.2	-0.2
Medication: Blood pressure	0.0	0.0	0.1	0.3	0.0
Ever smoked	0.0	0.0	0.1	-0.3	0.1
Medication: Omeprazole (e.g. Zanprol)	0.0	0.0	0.0	0.1	0.2
Pack years of smoking	0.0	0.0	0.1	0.0	0.3

Hub : Genes

DAGLA

Models

Trait associations