Hub : Genes

DCLK2

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0880 0.0270 1.6e-08 0.056 0.074 0.082 0.072 0.076 2.1e-07 2.6e-09 3.3e-10 3.8e-09 1.4e-09
2 GTEx Heart Left Ventricle 0.1128 0.0469 6.9e-04 0.016 NA 0.023 NA 0.027 4.8e-02 NA 2.1e-02 NA 1.4e-02
3 GTEx Lung 0.0657 0.0320 5.7e-03 -0.003 NA -0.003 NA -0.003 7.6e-01 NA 7.9e-01 NA 6.2e-01
4 GTEx Spleen 0.3620 0.1070 2.0e-04 0.082 NA 0.165 NA 0.070 3.9e-03 NA 5.2e-05 NA 7.2e-03
5 GTEx Whole Blood 0.0940 0.0390 4.3e-04 0.053 NA 0.023 NA 0.035 1.2e-05 NA 3.1e-03 NA 3.2e-04
6 METSIM Adipose 0.0994 0.0340 3.8e-05 0.053 0.036 0.048 0.041 0.047 1.9e-08 3.4e-06 1.1e-07 7.9e-07 1.1e-07
7 NTR Blood 0.0501 0.0169 2.0e-06 0.040 0.023 0.032 0.030 0.035 6.6e-13 5.9e-08 1.6e-10 4.2e-10 2.0e-11
8 TCGA Thyroid Carcinoma 0.0660 0.0410 5.0e-03 0.007 0.018 0.022 NA 0.019 6.9e-02 6.1e-03 2.7e-03 NA 5.2e-03

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.4 0.6 2.3 -0.6 0.5 -0.8 1.1 0.3 1.5 0.3 -0.3
Bipolar Disorder or Schizophrenia 0.4 1.0 2.7 -1.2 0.8 -1.4 1.0 -0.4 0.5 -0.5 -1.6
Depressed Affect (Nagel 2018) 1.7 3.6 8.2 2.9 -1.8 -0.4 -2.2 -1.6 -0.5 -1.7 2.5
Depression (Nagel 2018) 1.2 1.8 4.4 1.9 -2.1 -1.5 -1.4 -0.7 -0.4 -0.8 0.9
Intelligence (Savage-Jansen 2018) 0.4 1.4 6.5 -0.7 0.7 1.1 -0.2 -0.5 -2.6 -0.4 -1.4
Neuroticism (Nagel 2018) 0.9 2.2 4.3 2.1 -0.7 -0.6 -1.9 -1.5 -1.7 -1.7 0.8
Schizophrenia (2018) 0.5 1.0 3.6 -1.1 0.6 -1.1 0.4 -0.7 -0.7 -0.9 -1.9
Schizophrenia vs Biploar Disorder 0.8 1.1 3.1 -1.8 0.8 0.4 1.1 0.6 0.9 0.4 -1.6
Worry (Nagel 2018) 0.2 0.5 1.6 0.1 0.7 -0.1 -0.5 -0.7 -1.3 -0.7 -0.6
Alzheimer’s Disease (in mother) 1.1 1.2 2.6 -0.1 0.9 1.3 0.9 1.6 1.3 1.6 -0.4
Alzheimer’s Disease (in father) 1.1 1.2 2.5 1.6 -1.2 -0.5 -1.2 -1.3 -0.2 -1.2 0.8
Alzheimer’s Disease (including proxy) 0.7 1.1 3.6 0.5 0.5 1.1 0.6 1.2 1.9 1.2 -0.2
Crohns Disease (2017) 0.3 0.6 3.9 0.5 -0.4 -2.0 0.1 -0.1 -0.0 -0.1 -0.6
Irritable Bowel Disease (IBD) 0.5 1.2 1.9 1.4 -1.2 -1.3 -1.2 -0.9 -0.1 -1.0 0.9
Ulcerative Colitis (UC) 0.6 1.1 2.6 1.2 -1.1 0.1 -1.6 -1.0 -0.2 -0.9 1.3
Major Depression (MDD) 0.9 1.1 3.4 -0.4 0.8 -1.4 1.1 0.8 0.6 0.7 -1.8
Reaction Time 1.1 2.0 4.6 -1.4 0.9 2.2 1.0 1.8 0.5 2.0 -0.8
Verbal and Numeric Reasoning (VNR) 0.5 1.3 3.9 -1.2 1.6 1.0 0.8 0.2 -0.8 0.3 -2.0
Breast Cancer 3.5 8.4 19.9 -4.5 3.6 3.5 2.8 2.1 0.5 2.1 -2.2
Ovarian Cancer 0.6 0.8 4.6 0.1 0.3 2.1 -0.4 -0.6 -0.1 -0.8 0.5
Prostate Cancer 0.5 0.7 1.8 -1.1 1.3 0.2 1.0 0.8 0.0 0.7 -0.7
Age at First Birth 0.6 0.8 1.9 -1.4 0.6 -1.0 1.0 1.2 0.1 1.1 -0.1
Bipolar Disorder (2011) 0.4 0.4 1.4 0.5 0.3 0.3 -0.2 -0.8 -0.2 -0.6 1.2
Body Mass Index (BMI) (2010) 0.3 0.4 1.2 -0.8 -0.1 0.6 -0.1 0.5 -1.1 0.7 -0.5
Coronary Artery Disease (CAD) 1.3 1.5 3.8 1.3 -0.8 -0.4 -1.2 -1.9 0.8 -1.9 0.5
Crohns Disease (2012) 1.3 2.2 4.7 1.8 -2.2 -1.7 -1.0 -1.5 0.0 -1.6 0.6
Mean Putamen Volume 5.3 6.0 12.0 2.4 -2.1 -1.6 -2.7 -2.6 -1.5 -2.6 3.5
Fasting Glucose 0.4 0.5 2.5 -0.5 0.6 0.7 0.2 -0.0 1.6 -0.3 0.5
HbA1C 0.1 0.1 0.3 0.6 -0.1 -0.3 -0.3 -0.2 -0.6 -0.3 -0.1
HDL Cholesterol 1.1 1.9 3.1 1.5 -0.9 -1.0 -1.4 -1.7 -0.6 -1.7 1.8
LDL Cholesterol 1.2 1.9 5.5 2.3 -1.9 -1.1 -0.3 0.2 2.0 0.2 0.7
Lupus 0.2 0.3 0.5 0.2 -0.5 -0.7 -0.6 -0.5 -0.6 -0.4 -0.6
Neuroticism (2016) 1.1 1.5 3.5 1.9 -0.6 1.1 -1.4 -0.6 -1.4 -0.7 1.4
Primary Biliary Cirrhosis 0.2 0.4 1.8 -0.9 -0.1 0.0 -0.2 -0.0 -0.4 0.0 -1.3
Rheumatoid Arthritis 0.6 0.8 1.8 -0.8 1.3 1.1 0.2 -0.7 0.9 -0.8 -1.0
Schizophrenia (2014) 0.4 0.8 2.8 -1.0 0.2 -1.7 0.5 -0.2 -0.7 -0.3 -1.3
Triglycerides 0.4 0.7 3.0 -1.1 0.3 -0.6 0.5 -0.2 0.8 -0.4 -1.7
Type 2 Diabetes (T2D) (2012) 0.2 0.2 0.5 -0.2 -0.7 -0.5 -0.2 0.0 -0.6 -0.0 -0.5
Ulcerative Colitis 1.0 1.5 2.7 1.4 -1.6 -0.5 -1.5 -1.0 0.1 -1.0 1.6
Blood Eosinophil Count 0.2 1.2 4.2 -1.3 1.5 2.0 0.7 0.3 0.4 0.2 -0.8
Blood Platelet Count 0.1 1.6 5.5 -2.4 1.3 1.8 0.4 0.7 -1.1 0.8 -0.5
Blood Red Count 1.1 10.9 18.7 -4.3 4.3 3.0 3.5 2.9 1.7 2.9 -3.0
Blood White Count 1.9 14.2 33.8 -5.8 4.3 2.8 3.8 3.6 0.5 3.6 -3.6
Heel T-Score 0.3 2.4 4.9 2.0 -1.3 -2.2 0.1 -1.6 1.6 -1.8 0.7
BMI 0.4 2.6 4.7 -1.7 1.3 1.6 1.5 1.2 2.2 1.5 -1.5
Height 0.2 4.8 13.5 3.7 -2.9 -3.6 -1.0 -0.4 -0.8 -0.7 1.4
Waist Hip Ratio (WHR) 0.1 0.6 1.8 0.4 -0.4 1.0 -0.6 0.1 -1.1 0.0 1.4
Systolic Blood Pressure 2.0 10.2 21.0 3.2 -4.6 -1.7 -3.9 -3.9 -0.6 -3.7 1.9
Smoking Status 1.4 3.3 6.5 1.9 -2.1 -2.6 -1.5 -2.0 0.3 -1.9 1.3
Allergy or Eczema 1.3 3.5 6.6 -1.9 1.2 -0.4 2.2 2.3 0.8 2.6 -2.3
Cardiovascular Disease 0.2 0.7 2.4 0.8 -1.6 -0.4 -0.9 -0.8 0.2 -0.7 -0.2
Hypothyroidism (self reported) 0.6 1.3 3.2 -1.8 1.8 0.4 1.1 0.8 -0.9 0.9 -0.7
Respiratory disease 0.1 0.2 0.7 0.2 0.3 0.1 0.7 0.3 0.5 0.3 -0.8
Type 2 Diabetes (T2D) (2018) 1.0 1.9 6.7 -2.6 1.4 1.3 0.9 1.3 -0.3 1.4 0.5
Lung FEV1/FVC ratio 0.1 0.6 1.6 0.4 0.8 0.6 0.9 0.8 0.3 0.9 -1.3
Lung FVC 2.7 13.5 29.5 -4.4 5.4 2.6 3.7 2.8 -1.0 2.5 -4.9
Neuroticism 0.6 1.5 4.3 0.9 0.3 1.1 -1.4 -1.1 -2.1 -1.2 1.0
Chronotype (morning person) 1.0 2.4 6.8 1.6 -0.7 2.3 -1.5 -0.7 0.9 -0.7 2.6
Hair Pigment 0.4 11.6 16.3 -4.0 4.0 3.2 3.8 3.8 1.9 3.9 -1.7
Tanning 0.2 2.3 5.0 1.4 -2.2 -2.2 -1.1 -1.7 -0.3 -1.6 -0.0
Hand grip strength (left) 0.7 1.8 6.4 1.2 -1.0 -2.5 -0.6 -1.2 -1.2 -1.4 -0.7
Number of treatments/medications taken 0.6 1.0 2.6 -1.1 0.1 0.1 1.1 1.0 1.6 1.2 -0.7
Average weekly spirits intake 2.4 3.0 4.5 1.3 -1.5 -1.7 -1.4 -2.0 -1.8 -1.9 2.1
Sensitivity / hurt feelings 0.7 1.2 5.3 -0.2 1.7 0.5 0.2 -0.4 -2.3 -0.6 -0.5
Frequency of depressed mood in last 2 weeks 1.7 2.4 5.4 1.9 -2.3 -1.7 -1.5 -0.4 -1.1 -0.4 1.8
Hearing difficulty/problems: Yes 1.1 1.7 3.1 -1.3 1.4 0.8 1.2 1.8 0.0 1.6 -1.3
Relative age of first facial hair 0.3 0.5 1.7 0.4 1.0 -0.6 0.6 0.5 0.7 0.3 1.3
Other serious medical condition/disability diagnosed by doctor 2.1 2.7 6.2 -1.9 1.0 1.1 1.8 1.6 2.5 1.8 -0.5
Ever used hormone-replacement therapy (HRT) 4.1 5.2 8.7 -2.5 3.0 0.6 2.5 2.8 0.7 2.8 -1.9
Ever had hysterectomy (womb removed) 1.9 2.1 4.3 -1.6 1.3 -0.2 1.7 1.6 -0.1 1.7 -2.1
Systolic blood pressure, automated reading 0.6 1.8 3.7 1.7 -1.9 -0.9 -1.7 -1.6 0.5 -1.3 0.7
Eye problems/disorders: Diabetes related eye disease 1.4 1.6 3.5 -1.7 1.0 0.8 1.1 1.7 0.4 1.9 -0.1
Angina 0.1 0.1 0.5 -0.2 0.1 -0.7 0.3 0.1 -0.3 0.0 0.2
Medication for hormone replacement therapy 1.7 1.9 3.5 -1.9 1.8 1.9 1.2 1.1 -0.1 1.0 -1.4
Vitamin and mineral supplements 0.9 1.2 2.5 0.5 -1.1 0.7 -1.3 -1.6 -0.1 -1.6 0.8
Supplements: Zinc 1.1 1.2 5.5 -0.2 0.2 -1.1 -1.1 -0.8 -2.3 -0.9 -0.7
Medication: Co-codamol 1.9 2.2 4.8 -1.4 0.4 0.8 1.7 1.8 2.2 1.9 -0.4
Medication: Metformin 0.8 1.1 4.4 -2.1 0.9 1.5 0.7 0.6 0.1 0.7 0.0
Diabetes (father) 4.9 6.0 8.1 -2.5 2.2 1.0 2.7 2.8 2.2 2.9 -2.8
Diabetes (mother) 4.0 5.1 9.2 -2.3 2.2 1.4 2.5 2.5 3.0 2.5 -0.6
Severe depression (siblings) 1.1 1.2 3.8 -1.0 0.7 -0.4 1.2 1.0 2.0 1.0 -0.7
Pack years adult smoking proportion 0.7 1.1 5.2 -1.1 -0.3 -0.5 0.7 -0.2 2.3 -0.2 1.2
Impedance of leg (right) 1.1 5.4 9.0 2.0 -1.8 -1.0 -2.9 -2.6 -3.0 -2.9 1.7
Leg fat-free mass (left) 0.2 1.2 4.1 0.4 -0.8 -1.4 1.1 0.7 2.0 0.9 -0.3
Trunk fat percentage 0.4 1.5 3.9 1.5 -1.3 -1.9 0.5 0.2 2.0 0.5 -0.5
Hand grip strength (right) 0.4 1.0 4.1 0.4 0.2 -1.8 0.6 0.4 -0.3 0.2 -2.0
Townsend deprivation index at recruitment 0.6 0.9 1.7 0.3 -1.2 -0.8 -0.8 -0.9 -1.3 -0.9 -0.8
Current tobacco smoking 1.4 2.3 4.1 2.0 -1.8 -2.0 -0.9 -1.5 1.0 -1.5 1.0
Average weekly fortified wine intake 0.2 0.3 0.6 0.3 0.4 0.6 0.1 -0.6 0.6 -0.7 0.4
Maternal smoking around birth 0.2 0.3 1.8 0.1 -0.0 0.4 -0.4 0.3 -0.0 0.3 1.3
Fed-up feelings 2.9 5.3 9.1 3.0 -2.8 -1.0 -2.8 -2.1 -0.7 -2.1 2.8
Frequency of unenthusiasm / disinterest in last 2 weeks 1.0 1.3 3.0 1.3 -1.7 -0.2 -1.6 -0.9 -0.7 -1.0 0.8
Relative age voice broke 0.8 1.2 3.7 0.8 0.7 -1.8 0.6 0.1 0.9 -0.1 1.9
Taking other prescription medications 1.1 1.7 5.8 -1.0 -0.3 0.5 1.3 1.5 2.4 1.6 -0.2
Age when periods started (menarche) 0.2 0.5 3.1 -0.4 0.6 -0.2 -0.3 0.5 -1.8 0.2 -0.1
Bilateral oophorectomy (both ovaries removed) 0.1 0.2 0.4 0.3 -0.5 -0.3 -0.1 0.4 -0.6 0.5 -0.3
Heel bone mineral density (BMD) T-score, automated (left) 0.3 0.7 3.1 0.6 0.1 -1.2 0.6 -0.4 1.8 -0.5 -0.5
Tinnitus: Yes, but not now, but have in the past 0.4 0.5 1.0 0.8 -0.5 -0.8 -0.5 -0.8 -0.3 -1.0 0.4
Qualifications: CSEs or equivalent 0.4 0.5 1.5 -1.1 0.3 0.1 0.4 -0.2 1.2 -0.2 1.1
Serious illness, injury or assault to yourself 0.5 0.6 2.0 -1.3 1.4 0.8 0.6 0.3 0.2 0.2 -0.5
High blood pressure 0.1 0.3 1.3 -0.5 -0.2 1.1 -0.4 -0.3 0.3 0.0 -0.6
Hayfever, allergic rhinitis or eczema 1.2 2.7 5.9 -1.6 1.1 -0.0 1.9 2.2 0.8 2.4 -1.6
Multivitamins +/- minerals 0.7 0.9 2.4 -0.1 0.8 -1.6 1.5 0.9 0.7 0.9 -0.3
Stomach or abdominal pain in last month 0.4 0.4 1.3 -0.7 0.6 0.9 0.2 0.6 -0.3 0.5 -1.1
Supplements: Glucosamine 0.6 0.8 1.8 -0.9 0.9 -1.4 0.7 0.9 -0.3 0.9 -0.9
Diverticular disease/diverticulitis (self-reported) 1.2 1.4 6.3 -0.9 0.5 0.2 1.2 0.9 0.8 1.1 -2.5
Medication: Atenolol 0.4 0.5 2.2 0.2 -0.2 -1.1 0.9 0.1 1.5 0.3 -0.0
Medication: Levothyroxine sodium 0.5 0.9 3.2 -1.8 1.0 0.1 1.1 0.2 0.8 0.2 -1.0
Sitting height 0.2 1.6 4.8 1.6 -1.9 -2.2 -0.7 -0.4 -0.5 -0.5 0.8
Chronic bronchitis/emphysema (father) 0.1 0.1 0.9 -0.2 -0.3 -0.9 0.4 0.0 0.0 0.1 -0.1
High blood pressure (mother) 0.4 0.6 2.7 0.6 -0.3 -0.4 -1.1 -0.3 -1.7 -0.2 -0.1
Body mass index (BMI) 0.9 3.7 8.4 -1.5 1.0 -0.1 2.3 1.9 2.9 2.2 -2.1
Impedance of leg (left) 0.8 4.1 10.3 1.7 -1.3 -1.1 -2.3 -2.1 -3.2 -2.4 1.2
Leg predicted mass (left) 0.2 1.2 4.2 0.4 -0.7 -1.4 1.1 0.7 2.1 0.9 -0.4
Trunk fat mass 0.3 1.3 3.5 1.2 -1.0 -1.9 0.6 0.5 1.8 0.8 -0.5
Waist circumference 0.4 1.5 4.9 -0.4 0.6 0.1 1.3 1.2 2.2 1.4 -1.1
Number of incorrect matches in round 0.4 0.7 1.7 -0.2 1.3 0.8 0.8 1.1 0.5 0.9 -0.1
Past tobacco smoking 0.5 1.0 2.1 -0.9 1.2 1.2 0.9 0.8 0.4 0.6 -1.4
Alcohol usually taken with meals 0.4 0.6 1.4 0.4 -1.2 0.9 -1.1 -0.3 0.0 -0.1 1.2
Nervous feelings 0.1 0.2 0.8 -0.2 0.8 -0.1 -0.1 0.2 -0.9 0.0 -0.0
Frequency of tenseness / restlessness in last 2 weeks 0.4 0.7 3.0 0.4 -0.2 1.0 -0.6 -0.4 -1.7 -0.4 -0.9
Hearing difficulty/problems with background noise 1.1 1.7 3.2 -1.2 1.2 -1.1 1.5 1.4 -0.1 1.5 -1.8
Hair/balding pattern: Pattern 2 0.1 0.2 0.5 0.5 -0.2 0.3 -0.4 -0.5 -0.7 -0.5 0.1
Had menopause 1.1 1.4 3.1 -1.7 1.6 0.8 0.9 0.5 0.4 0.6 -1.8
Had other major operations 6.4 7.9 12.5 -3.3 3.1 2.7 3.0 3.3 1.0 3.5 -1.6
Forced vital capacity (FVC) 0.8 2.9 10.4 -1.6 2.3 -0.0 1.9 0.7 -0.9 0.4 -3.2
Heel bone mineral density (BMD) T-score, automated (right) 0.3 0.7 1.8 0.7 -0.1 -1.0 -0.0 -1.1 0.7 -1.3 -0.7
Ever unenthusiastic/disinterested for a whole week 0.3 0.4 1.1 0.2 0.2 -1.0 0.6 0.8 -0.4 0.8 -0.6
Qualifications: None of the above 0.1 0.1 0.3 0.2 -0.6 -0.1 -0.5 -0.5 -0.0 -0.4 -0.1
Financial difficulties in last 2 years 0.3 0.4 0.9 -0.8 1.0 0.4 0.9 0.6 0.1 0.7 -0.2
Mouth/teeth dental problems 0.1 0.2 0.6 -0.5 -0.8 0.2 -0.4 -0.5 -0.2 -0.4 -0.0
Heart attack 0.3 0.3 0.7 -0.4 0.3 0.6 0.4 0.8 0.1 0.8 0.8
Allergy 2.5 5.8 10.4 2.5 -1.8 -0.4 -2.8 -3.2 -1.5 -3.2 2.3
Pain all over the body in last month 2.8 3.0 7.0 -2.6 1.6 1.8 1.8 1.6 1.3 1.6 -0.8
Diabetes (self-reported) 0.4 0.6 2.7 -1.6 0.5 0.8 0.4 0.6 -0.5 0.7 0.1
Hayfever/allergic rhinitis (self-reported) 0.6 0.8 2.4 -1.1 0.1 0.7 0.6 0.4 1.1 0.5 -1.6
Medication: Ramipril 1.2 1.6 3.2 1.8 -1.1 -1.3 -1.6 -0.8 -1.3 -0.8 1.1
Medication: Simvastatin 0.6 0.9 3.2 0.7 -1.8 -1.4 -0.7 -0.7 0.2 -0.5 -0.2
Fluid intelligence score 0.3 0.7 2.0 -0.9 0.8 0.4 -0.0 -0.4 -1.4 -0.3 -1.4
Illnesses of siblings 1.5 2.1 7.3 -0.6 0.4 0.5 1.4 2.7 1.2 2.4 -0.0
Neuroticism score 0.7 1.4 5.0 1.0 -0.0 0.7 -1.3 -1.0 -2.2 -1.1 0.9
Weight 0.2 1.2 3.1 0.5 -0.5 -1.6 1.0 0.8 1.8 1.1 -0.7
Impedance of arm (right) 2.1 9.7 20.0 4.5 -4.1 -2.7 -3.1 -2.9 -0.8 -3.2 2.0
Arm fat percentage (right) 0.4 1.6 6.4 0.3 -0.6 -1.3 1.0 0.6 2.5 1.0 -1.3
Trunk fat-free mass 0.0 0.2 0.5 -0.4 0.3 -0.5 0.6 0.6 -0.0 0.7 -0.2
Hip circumference 0.5 2.0 8.5 -0.0 -0.1 -1.8 1.4 0.6 2.9 0.8 -1.3
Time employed in main current job 0.4 0.4 2.0 -0.5 0.9 1.4 0.2 0.1 0.5 0.0 0.3
Alcohol intake versus 10 years previously 0.7 1.1 3.1 0.1 0.6 1.8 0.6 1.4 -0.0 1.4 -1.0
Father’s age at death 0.4 0.5 1.0 -0.7 1.0 0.9 0.3 0.5 -1.0 0.6 -0.3
Worrier / anxious feelings 0.4 0.8 4.2 -0.2 0.8 1.1 -0.5 -0.3 -2.0 -0.4 0.0
Frequency of tiredness / lethargy in last 2 weeks 1.9 3.0 7.1 -2.7 1.9 1.5 2.1 1.1 1.5 1.2 -1.5
Falls in the last year 5.0 6.7 12.8 -2.8 2.7 1.4 3.6 2.4 3.2 2.3 -1.4
Hair/balding pattern: Pattern 3 0.5 0.8 3.3 0.7 0.1 -0.5 -1.0 -0.6 -1.8 -0.8 -0.6
Number of live births 1.2 1.8 3.7 1.9 -1.9 -1.8 -1.1 -1.0 0.2 -1.1 0.2
Forced expiratory volume in 1-second (FEV1) 1.4 4.7 16.9 -2.1 2.8 0.0 2.5 1.1 -0.4 0.8 -4.1
Pulse rate 0.2 0.4 1.6 -0.1 0.4 -0.2 0.4 0.6 1.3 0.6 0.8
Happiness 0.9 1.1 2.5 0.0 -0.8 -1.6 -0.8 -1.3 -1.2 -1.3 0.6
Noisy workplace 4.6 5.6 8.7 -2.4 2.7 2.0 2.4 2.9 -0.5 2.8 -2.3
Qualifications: A levels/AS levels or equivalent 0.6 1.3 3.0 0.8 -0.0 1.2 -1.2 -1.7 -0.9 -1.7 0.2
Serious illness, injury or assault of a close relative in last 2 years 0.5 0.6 3.7 -0.5 0.6 1.9 -0.0 0.1 0.4 0.0 0.4
Mouth/teeth dental problems: Dentures 0.2 0.4 1.2 0.3 0.8 -1.1 0.2 -0.3 0.4 -0.4 0.8
Asthma 0.5 1.0 3.4 -0.4 0.4 0.9 1.0 1.2 1.8 1.1 -0.3
Medication: Ibuprofen (e.g. Nurofen) 5.0 6.4 9.2 3.0 -3.0 -2.0 -2.9 -3.0 -0.8 -2.7 1.9
Medication: Cholesterol lowering 1.4 2.2 4.7 2.1 -2.2 -1.3 -1.6 -1.2 -0.8 -1.2 0.6
Depression (self-reported) 0.5 0.6 1.3 0.3 -0.7 -0.8 -0.9 -1.1 -0.4 -1.1 0.3
Medication: Lansoprazole 0.9 1.1 3.6 -1.1 0.7 0.2 1.3 0.6 1.9 0.6 -0.7
Prospective memory result 0.9 1.1 2.4 0.2 -0.4 -1.1 -0.5 -1.5 0.5 -1.5 1.5
Lung cancer (father) 1.1 1.3 3.3 0.6 -1.1 -0.6 -1.2 -1.2 -1.8 -1.2 -1.0
Illnesses of mother 0.3 0.3 1.3 -0.1 -0.0 0.3 0.0 -1.1 0.3 -1.1 -0.3
Forced expiratory volume in 1-second (FEV1), Best measure 1.0 3.3 9.7 -1.4 2.1 -0.5 2.2 1.6 -0.6 1.5 -3.1
Pulse wave Arterial Stiffness index 4.6 5.4 7.2 2.4 -2.7 -1.9 -2.4 -2.4 -1.4 -2.4 2.7
Impedance of arm (left) 1.9 8.7 18.2 4.3 -3.8 -2.7 -2.8 -2.7 -0.5 -2.9 2.2
Arm fat mass (right) 0.4 1.6 6.4 0.1 -0.5 -1.7 1.2 0.7 2.5 1.0 -0.9
Trunk predicted mass 0.0 0.2 0.6 -0.5 0.3 -0.4 0.7 0.7 0.0 0.7 -0.1
Standing height 1.0 9.7 19.3 4.4 -3.6 -3.4 -2.8 -2.4 -2.2 -2.6 2.9
Length of working week for main job 0.3 0.3 0.8 0.4 -0.9 -0.5 -0.1 -0.6 0.3 -0.6 -0.9
Exposure to tobacco smoke at home 0.5 0.6 2.0 0.3 -0.4 -1.1 -0.8 -0.6 -1.4 -0.5 0.3
Breastfed as a baby 1.1 1.4 6.0 1.5 -0.4 1.1 -1.1 -0.2 -2.4 -0.0 0.3
Tense / ‘highly strung’ 0.6 0.9 2.0 1.1 -0.6 -0.3 -1.3 -1.4 -0.3 -1.4 0.3
Seen doctor (GP) for nerves, anxiety, tension or depression 0.5 0.8 3.2 0.6 -0.6 -1.8 0.2 0.6 1.2 0.7 0.3
Hair/balding pattern: Pattern 4 0.5 1.3 2.1 -1.0 0.7 1.0 1.4 1.4 1.1 1.5 -0.2
Birth weight of first child 0.5 0.9 3.6 -0.7 0.2 1.2 0.8 0.4 1.9 0.6 0.5
Peak expiratory flow (PEF) 0.7 1.6 6.4 -0.6 0.8 -1.9 1.1 -0.3 -0.2 -0.3 -2.5
Pulse wave reflection index 0.7 0.9 2.4 0.4 -1.5 -1.3 -1.0 -0.6 -1.0 -0.5 0.4
Ever highly irritable/argumentative for 2 days 1.2 1.5 2.5 -0.9 1.6 0.6 1.5 1.4 1.1 1.4 -0.7
Loud music exposure frequency 1.7 1.9 3.0 -1.4 1.6 0.9 1.2 1.7 -0.5 1.7 -1.4
Qualifications: O levels/GCSEs or equivalent 0.9 1.4 5.8 0.4 -0.3 0.1 -1.4 -1.0 -2.4 -0.9 1.2
Mouth/teeth dental problems: Bleeding gums 0.3 0.4 1.9 1.4 -0.7 0.5 -0.7 -0.0 -0.5 -0.0 -0.4
Blood clot in the leg (DVT) 1.4 1.9 3.3 -1.6 1.8 0.4 1.8 1.4 1.0 1.3 -1.1
Medication: Paracetamol 0.3 0.4 2.4 -0.2 -0.5 0.7 0.3 0.3 1.6 0.3 0.1
Headache pain in last month 0.4 0.7 1.8 -0.4 0.2 1.0 0.3 1.3 0.7 1.3 -0.5
Medication for cholesterol, blood pressure or diabetes 1.4 2.4 4.6 -2.1 2.0 0.4 1.6 1.9 -0.5 1.9 -0.6
Glaucoma (self-reported) 0.4 0.5 1.6 -0.5 0.6 -0.5 0.9 0.2 -0.5 0.4 -1.3
Gout (self-reported) 0.7 0.9 1.6 -1.1 1.1 1.2 1.0 1.0 0.7 0.8 -0.7
Hypothyroidism/myxoedema (self-reported) 0.9 1.7 5.8 -2.4 1.9 0.5 1.4 0.9 0.4 1.0 -0.6
Medication: Amlodipine 0.5 0.7 1.6 0.4 0.5 1.3 -0.5 -1.2 -0.2 -1.3 -0.3
Medication: Ventolin 100micrograms inhaler 1.1 1.4 5.9 1.4 -1.3 -0.5 -0.6 0.3 0.8 0.2 2.4
Birth weight 0.2 0.3 0.9 0.2 0.5 -0.5 0.9 0.5 0.9 0.4 0.2
Chronic bronchitis/emphysema (mother) 0.9 1.0 2.9 -1.1 1.7 0.4 1.0 1.0 -0.9 1.0 -0.2
High blood pressure (siblings) 1.1 1.6 4.2 -0.4 0.0 0.0 -1.6 -2.0 -1.6 -1.9 0.1
Forced vital capacity (FVC), Best measure 0.6 2.1 6.1 -1.1 1.5 -0.5 1.7 1.2 -1.4 1.0 -2.5
Body fat percentage 0.3 1.2 4.0 0.7 -0.6 -1.5 0.8 0.5 2.0 0.9 -1.0
Leg fat percentage (right) 0.3 1.2 2.6 -0.8 0.6 -0.1 1.3 1.0 1.6 1.2 -1.4
Arm fat-free mass (right) 0.1 0.6 1.5 -0.9 0.6 -0.5 1.2 0.8 0.4 1.0 -0.4
Exposure to tobacco smoke outside home 0.1 0.1 0.4 -0.1 0.1 0.1 0.3 -0.2 -0.2 -0.2 -0.7
Comparative body size at age 10 1.5 4.0 6.5 2.3 -2.3 -2.0 -2.5 -2.3 -0.4 -2.2 0.8
Number of full brothers 0.4 0.4 1.0 -0.4 0.4 1.0 0.1 -0.6 0.8 -0.6 -0.9
Worry too long after embarrassment 0.7 1.2 5.4 -0.1 0.8 0.1 -0.8 -1.1 -2.3 -1.1 -0.3
Seen a psychiatrist for nerves, anxiety, tension or depression 0.3 0.3 1.1 1.1 -0.2 -1.0 -0.6 -0.1 -0.3 -0.1 0.4
Wheeze or whistling in the chest in last year 0.3 0.6 1.6 0.3 -1.3 0.9 -0.3 0.7 1.1 0.7 0.5
Number of children fathered 0.4 0.4 1.8 0.4 0.1 1.4 -0.4 -0.5 -0.7 -0.5 0.6
Reason for reducing amount of alcohol drunk: Health precaution 1.1 1.3 3.4 1.8 -1.1 -1.3 -1.3 -0.6 -1.4 -0.6 -0.2
Age at first live birth 1.0 1.9 6.1 0.3 -0.1 1.5 -1.7 -0.9 -2.5 -1.0 1.3
Pulse wave peak to peak time 3.6 4.2 6.0 -2.1 2.3 1.4 2.3 2.1 1.4 2.1 -2.5
Health satisfaction 2.3 3.0 7.1 -2.7 2.5 1.2 1.6 1.2 -0.2 1.1 -2.0
Shortness of breath walking on level ground 0.6 0.7 3.3 -1.1 0.4 0.8 0.1 -0.3 1.8 -0.3 -0.0
Qualifications: College or University degree 0.3 1.1 3.8 -0.6 1.5 2.0 0.9 0.7 0.6 0.6 -0.3
Eye problems/disorders: None of the above 0.1 0.1 0.4 0.3 0.1 0.2 -0.6 -0.5 -0.0 -0.6 -0.2
Mouth/teeth dental problems: Loose teeth 0.3 0.4 0.9 0.8 -0.9 0.3 -0.4 0.2 -0.9 0.4 0.6
Emphysema/chronic bronchitis 0.3 0.4 1.5 0.3 -0.0 0.2 0.3 0.7 1.2 0.7 -0.4
Medication for pain relief, constipation, heartburn 0.8 1.3 3.7 -1.7 1.9 0.8 0.5 0.6 -1.5 0.4 -0.6
Neck or shoulder pain in last month 0.5 0.7 4.1 0.6 0.6 2.0 0.3 0.4 0.8 0.3 -0.1
Medication: Blood pressure 2.1 3.7 7.4 2.3 -2.0 -0.5 -2.1 -2.7 0.3 -2.7 1.2
Angina (self-reported) 0.1 0.2 0.3 -0.4 0.5 -0.5 0.5 0.5 -0.4 0.3 0.1
Migraine (self-reported) 0.8 0.9 3.5 0.5 -1.0 -1.9 -0.8 -0.7 -0.7 -0.9 -0.3
Medication: Ibuprofen 3.0 3.6 6.0 2.5 -2.0 -1.0 -2.1 -2.4 0.1 -2.2 1.8
Medication: Allopurinol 1.6 2.2 3.4 -1.5 1.6 1.9 1.3 1.8 0.3 1.7 -1.2
Medication: Omeprazole 1.2 1.5 4.2 -1.0 -0.1 -0.9 1.5 1.3 2.0 1.4 -0.0
Medication: Seretide 50 evohaler 1.9 2.2 4.8 -1.2 1.3 2.2 0.8 1.9 1.2 1.8 0.8
Mean time to correctly identify matches 1.6 3.1 6.6 -1.7 2.0 2.6 1.2 1.9 0.0 2.1 -1.4
Heart disease (mother) 1.3 1.6 2.6 -1.6 1.4 -1.0 1.5 1.4 -0.3 1.4 -0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.8 2.1 3.9 0.8 -1.3 -1.4 -1.8 -2.0 -1.4 -1.8 0.8
Whole body fat mass 0.3 1.2 3.2 0.4 -0.4 -1.5 1.0 0.7 1.8 1.1 -1.1
Leg fat mass (right) 0.3 1.1 3.0 -0.3 0.2 -0.7 1.1 1.0 1.7 1.3 -1.0
Arm predicted mass (right) 0.3 1.3 2.8 -1.3 1.0 -0.3 1.7 1.2 1.0 1.4 -0.6
Pulse rate, automated reading 0.5 1.5 3.8 -1.6 0.9 0.3 1.3 0.7 1.4 0.9 -1.9
Alcohol intake frequency. 0.6 1.5 4.1 1.8 -2.0 -0.4 -1.4 -0.8 -0.9 -0.9 -0.6
Comparative height size at age 10 1.2 6.6 11.0 3.3 -3.1 -3.0 -2.5 -1.5 -2.2 -1.6 2.7
Number of full sisters 1.1 1.3 5.8 -0.4 0.9 0.8 1.2 0.9 0.1 0.9 -2.4
Suffer from ‘nerves’ 1.0 1.6 2.6 -1.5 1.4 -0.5 1.2 1.3 -0.4 1.5 -1.6
Overall health rating 1.6 3.4 8.1 -2.8 2.0 1.9 1.9 1.8 0.9 1.9 -0.5
Chest pain or discomfort 2.6 3.8 5.6 -1.8 1.4 2.2 2.2 2.3 1.9 2.4 -0.8
Had major operations 2.3 2.7 5.6 -2.4 1.8 1.2 1.2 1.8 -0.5 1.7 -1.9
Age at last live birth 2.7 4.0 9.0 1.8 -1.1 0.8 -2.5 -2.3 -3.0 -2.3 1.1
Family relationship satisfaction 1.4 1.7 3.9 0.5 -0.8 -1.4 -1.3 -2.0 -0.9 -1.9 0.6
Leg pain on walking 2.6 3.2 7.0 -2.2 2.6 1.0 2.1 1.5 0.6 1.4 -1.9
Qualifications: NVQ or HND or HNC or equivalent 0.8 1.0 3.6 -0.9 -0.0 -1.9 1.4 0.7 0.6 0.6 -0.3
Commuting to job workplace: Car/motor vehicle 0.3 0.3 2.3 -0.3 0.4 1.5 -0.0 -0.2 -0.1 -0.1 0.1
Illness, injury, bereavement, stress in last 2 years 0.7 0.9 1.5 0.1 -1.0 -1.1 -1.1 -1.1 0.3 -1.2 0.9
Medication: Aspirin 0.6 0.8 2.3 1.5 -1.4 -0.9 -0.6 -0.3 0.4 -0.2 0.7
Supplements: Vitamin C 0.4 0.5 1.9 -0.1 0.6 -0.3 -0.4 0.4 -1.4 0.4 -1.1
Knee pain experienced in last month 1.7 2.7 5.0 -1.3 2.2 1.2 1.8 1.5 1.6 1.5 -1.8
Hypertension (Self-reported) 0.1 0.2 0.9 -0.3 -0.2 0.6 -0.2 -0.4 0.3 -0.1 -1.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.3 0.4 1.9 -0.5 0.3 0.3 0.3 -0.4 -0.7 -0.2 -1.4
Illnesses of father: Heart disease 1.0 1.4 2.9 -1.5 0.6 -0.6 1.2 1.6 -0.1 1.7 -1.1
Illnesses of siblings: Diabetes 0.1 0.2 0.4 -0.3 -0.2 -0.1 -0.2 -0.6 -0.1 -0.6 -0.7
Smoking status: Previous 0.1 0.2 1.1 -0.1 -0.1 0.3 -0.4 -0.1 -0.6 0.1 1.0
Forced expiratory volume in 1-second (FEV1), predicted 1.1 2.3 7.8 1.2 -2.2 -2.8 -0.8 -0.8 -0.8 -0.9 0.9
Whole body fat-free mass 0.1 0.4 0.8 -0.2 -0.0 -0.9 0.9 0.6 0.8 0.8 -0.3
Leg fat-free mass (right) 0.2 1.3 3.7 0.3 -0.6 -1.5 1.3 0.8 1.9 1.1 -0.4
Arm fat percentage (left) 0.5 2.0 8.1 0.0 -0.2 -1.2 1.4 0.8 2.9 1.2 -1.4
Average weekly red wine intake 0.4 0.6 1.5 -1.0 1.2 0.5 0.9 -0.2 0.6 -0.2 -0.9
Handedness (chirality/laterality): Left-handed 0.7 0.9 1.9 0.7 0.2 -0.9 -0.3 -1.2 -1.3 -1.4 0.7
Mood swings 1.5 2.7 7.2 2.2 -0.9 1.4 -1.5 -1.5 -0.7 -1.6 2.7
Loneliness, isolation 4.1 5.7 10.3 3.2 -2.8 -0.9 -3.0 -2.1 -1.4 -2.1 2.5
Long-standing illness, disability or infirmity 3.0 4.6 7.5 -2.7 2.5 1.9 2.6 2.0 1.2 2.1 -1.7
Ever had bowel cancer screening 1.5 1.7 3.9 1.6 -1.6 -0.3 -1.9 -0.7 -0.5 -0.5 2.0
Diabetes diagnosed by doctor 0.4 0.7 2.5 -1.6 0.5 0.7 0.5 0.9 0.2 1.1 0.5
Ever had stillbirth, spontaneous miscarriage or termination 1.3 1.3 3.3 -1.8 1.4 0.6 0.9 0.9 -0.1 1.1 -1.5
Friendships satisfaction 1.0 1.2 2.4 0.4 -0.4 -0.3 -1.3 -1.3 -1.4 -1.3 1.5
Qualifications: nursing, teaching 1.2 1.9 4.1 1.5 -1.0 -0.4 -1.3 -2.0 -1.5 -2.0 0.3
Commuting to job workplace: Walk 1.5 1.6 3.2 -1.3 1.5 -0.1 1.3 1.2 -1.0 1.3 -1.8
Eye problems/disorders: Cataract 1.1 1.3 2.5 -1.0 0.6 1.0 1.6 1.4 0.7 1.4 -0.7
Mouth/teeth dental problems: Mouth ulcers 3.1 5.0 8.1 -2.0 2.1 -0.5 2.7 2.8 1.2 2.6 -2.7
Medication for cholesterol 2.5 3.7 7.6 2.8 -2.1 -1.8 -2.0 -1.8 -0.8 -2.0 1.7
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.3 0.3 1.0 0.6 0.2 -1.0 0.2 0.1 1.0 0.0 0.0
Back pain experienced in last month 5.0 7.3 9.5 -2.8 2.3 2.3 2.9 3.0 3.0 3.1 -1.8
Mineral and other dietary supplements 1.0 1.4 2.8 1.2 -1.7 0.7 -1.2 -1.5 -0.3 -1.4 0.9
Breast cancer (self-reported) 0.2 0.3 0.6 0.2 0.2 0.4 0.2 0.7 -0.8 0.7 -0.6
Asthma (self-reported) 0.5 1.1 4.3 -0.4 0.4 1.0 1.0 1.1 2.1 1.0 -0.0
Osteoporosis (self-reported) 1.0 1.2 4.0 -1.4 0.7 0.5 0.9 0.8 2.0 0.6 -1.0
Osteoarthritis (self-reported) 1.6 2.0 4.7 -1.6 1.7 -0.4 2.2 0.8 1.2 0.9 -1.7
Medication: Aspirin 0.7 0.9 2.4 1.4 -1.4 -1.5 -0.5 -0.2 0.1 -0.1 0.4
Medication: Gliclazide 0.3 0.4 1.3 -0.5 -0.5 1.0 0.2 0.2 0.4 0.2 1.1
Illnesses of father: None of the above (group 1) 1.4 1.7 2.3 1.4 -1.5 -1.2 -1.3 -1.1 -1.1 -1.3 1.3
Smoking status: Current 1.7 2.7 4.8 2.2 -1.9 -2.1 -1.1 -1.7 0.7 -1.7 0.9
Forced expiratory volume in 1-second (FEV1), predicted percentage 2.1 4.4 7.7 -1.9 2.8 1.0 2.4 2.4 -1.2 2.2 -2.4
Whole body water mass 0.1 0.5 1.1 -0.3 -0.1 -1.1 0.9 0.7 0.7 0.9 -0.3
Leg predicted mass (right) 0.3 1.3 3.8 0.1 -0.5 -1.4 1.4 0.9 2.0 1.1 -0.6
Arm fat mass (left) 0.4 1.8 6.3 -0.1 -0.3 -1.5 1.3 1.0 2.5 1.3 -1.0
Number of self-reported non-cancer illnesses 2.2 3.8 5.5 -2.4 1.5 0.9 2.3 2.0 2.0 2.2 -1.8
Average weekly champagne plus white wine intake 0.8 1.1 5.2 -0.6 0.5 2.3 -0.9 -0.7 -0.1 -0.6 1.2
Miserableness 1.5 2.6 4.9 2.2 -1.7 -1.1 -1.8 -1.6 -1.8 -1.5 0.6
Guilty feelings 1.3 1.9 3.2 1.4 -0.5 1.1 -1.6 -1.5 -1.8 -1.6 1.1
Wears glasses or contact lenses 0.1 0.1 0.2 -0.4 0.4 0.3 -0.0 0.0 -0.1 -0.1 0.1
Ever taken oral contraceptive pill 0.4 0.4 1.2 0.7 -1.1 0.3 -0.7 0.0 -0.9 -0.2 0.4
Hearing aid user 1.0 1.1 2.6 -1.6 1.2 0.9 0.3 -0.1 -1.2 -0.3 -1.6
Mother’s age at death 0.3 0.3 0.9 0.3 0.2 -0.8 0.4 0.8 -0.0 0.9 0.4
Financial situation satisfaction 0.7 0.8 2.1 0.6 -0.5 -0.2 -0.9 -0.9 -1.1 -1.0 1.5
Tinnitus: Yes, now most or all of the time 2.0 2.3 4.8 -2.2 1.2 -0.8 1.5 1.9 -0.1 1.8 -1.6
Commuting to job workplace: Public transport 1.8 2.1 4.0 -1.3 1.4 -1.0 1.8 1.8 -0.6 2.0 -1.1
Eye problems/disorders: Glaucoma 0.1 0.1 0.4 -0.2 0.1 -0.6 0.6 -0.1 0.1 -0.0 -0.2
Medication: Blood pressure 0.6 1.1 3.4 -1.9 1.6 1.4 0.6 0.5 -0.1 0.8 -0.3
Pain type(s) experienced in last month: Hip pain 0.2 0.2 0.5 0.1 0.5 0.6 -0.0 -0.7 0.2 -0.5 0.4
Supplements: Fish oil (including cod liver oil) 0.8 1.1 2.1 -1.2 1.5 -1.1 0.9 1.1 -0.1 1.3 -0.3
High cholesterol (Self-reported) 1.6 2.9 7.9 2.0 -2.8 -2.0 -1.4 -1.7 0.2 -1.5 0.3
Medication: Bendroflumethiazide 0.6 0.9 3.0 0.1 -0.6 0.0 -1.2 -1.7 -0.3 -1.5 -0.7
Medication: Paracetamol 0.6 0.9 2.1 -0.8 0.2 1.3 0.8 1.0 1.5 1.1 -0.1
Medication: Lisinopril 0.3 0.4 1.7 -0.5 0.2 -0.5 0.9 0.1 1.3 0.1 -0.2
Medication: Atorvastatin 1.0 1.3 2.5 -1.0 0.3 0.2 1.4 1.6 1.4 1.6 -0.5
Illnesses of father: High blood pressure 0.7 0.8 1.9 0.8 -0.4 -0.4 -0.4 -1.4 0.7 -1.3 1.1
Alcohol drinker status: Never 0.5 0.6 2.4 0.5 -0.7 -1.5 0.4 0.3 -0.0 0.2 -1.2
Ever smoked 0.7 1.3 2.3 1.4 -1.4 -1.2 -1.1 -1.0 -0.2 -0.9 1.5
Basal metabolic rate 0.1 0.7 1.8 0.0 -0.4 -1.3 0.9 0.6 1.1 0.8 -0.4
Leg fat percentage (left) 0.5 1.9 3.4 -1.2 1.1 -0.1 1.7 1.3 1.5 1.6 -1.9
Arm fat-free mass (left) 0.2 0.8 1.6 -1.0 0.5 -0.8 1.3 1.0 0.5 1.2 -0.7
Number of operations (self-reported) 6.8 10.1 16.7 -4.1 3.9 1.9 3.5 3.7 0.5 3.7 -2.3
Average weekly beer plus cider intake 0.6 0.9 4.1 -0.2 0.3 -1.0 1.1 0.1 0.7 0.1 -2.0
Irritability 0.8 1.4 3.9 1.6 -0.4 1.0 -1.4 -0.7 -2.0 -0.8 0.7
Risk taking 1.0 1.4 2.5 -1.0 1.3 1.3 1.6 0.8 1.4 0.7 -1.1
Ever had prostate specific antigen (PSA) test 0.9 1.0 3.1 1.8 -0.5 1.3 -1.0 -1.1 0.1 -1.0 -0.1
Fractured/broken bones in last 5 years 0.6 0.8 2.5 -1.4 0.9 1.6 0.6 -0.5 -0.0 -0.4 -0.6
Age started oral contraceptive pill 1.9 2.3 5.9 -1.5 2.4 0.8 1.9 0.8 1.1 0.6 -2.0
Diastolic blood pressure, automated reading 0.3 0.8 3.4 -0.2 -1.0 -1.9 -0.2 -0.9 0.8 -0.6 -0.6
Ever depressed for a whole week 0.3 0.3 1.6 0.4 -0.4 -1.3 0.0 -0.4 0.7 -0.3 0.0
Unable to work because of sickness or disability 1.0 1.3 2.7 -1.4 1.1 -0.4 1.2 1.5 0.7 1.7 0.5
Commuting to job workplace: Cycle 3.5 4.3 9.5 1.5 -2.0 -1.5 -2.3 -2.9 -1.4 -3.1 0.6
Myopia 0.5 0.7 2.1 -1.0 0.3 1.4 0.5 0.8 -0.4 1.0 -0.8
Vascular/heart problems diagnosed by doctor 0.1 0.3 1.0 0.6 -0.1 -1.0 -0.1 -0.3 -0.7 -0.5 0.5
Cholesterol lowering medication 0.5 0.7 2.3 -1.0 -0.4 -0.2 0.6 0.7 1.5 0.8 -0.6
Medication: Omeprazole (e.g. Zanprol) 1.5 1.8 3.6 -1.5 0.5 -0.3 1.9 1.6 1.8 1.6 0.2
Pain experienced in last month 3.9 6.5 14.7 2.5 -2.8 -3.8 -2.1 -2.5 -2.7 -2.5 0.2
Supplements: Calcium 1.6 1.8 5.0 -0.9 0.9 0.0 1.2 2.2 1.0 2.1 -0.8
Basal cell carcinoma (self-reported) 0.8 1.0 3.6 -0.6 0.9 -0.1 1.3 0.7 1.9 0.7 -0.6
Heart attack/myocardial infarction (self-reported) 0.3 0.4 0.6 -0.5 0.3 0.7 0.6 0.8 0.2 0.8 0.5
Deep venous thrombosis (DVT) (self-reported) 1.2 1.6 2.7 -1.5 1.6 0.4 1.7 1.3 0.8 1.2 -1.1
Heart disease (siblings) 0.3 0.4 2.2 0.2 -0.2 -0.1 0.3 -0.6 0.5 -0.4 -1.5
Alcohol drinker status: Previous 0.8 0.9 4.8 -0.4 0.3 2.2 -0.3 -0.4 0.9 -0.6 -1.0
Pack years of smoking 0.7 1.0 4.6 -1.3 0.2 0.3 0.9 0.3 2.1 0.2 0.9
Impedance of whole body 1.5 7.4 12.7 3.6 -3.1 -2.3 -2.9 -2.7 -1.8 -3.0 1.9
Leg fat mass (left) 0.4 1.5 3.0 -0.6 0.5 -0.6 1.5 1.2 1.7 1.6 -1.3
Arm predicted mass (left) 0.1 0.6 1.2 -0.7 0.3 -0.8 1.1 0.9 0.5 1.0 -0.3