Hub : Genes

DDT

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.2000 0.0370 0.0e+00 0.134 0.198 0.185 0.200 0.190 6.0e-16 1.6e-23 4.9e-22 7.1e-24 1.2e-22
2 GTEx Adipose Subcutaneous 0.1580 0.0420 8.9e-07 0.094 NA 0.068 NA 0.070 4.5e-08 NA 3.3e-06 NA 2.4e-06
3 GTEx Adipose Visceral Omentum 0.1340 0.0560 6.0e-03 0.072 NA 0.041 NA 0.048 1.3e-04 NA 3.2e-03 NA 1.7e-03
4 GTEx Artery Aorta 0.2500 0.0560 2.8e-08 0.151 NA 0.191 NA 0.126 1.1e-08 NA 9.6e-11 NA 2.1e-07
5 GTEx Artery Tibial 0.2490 0.0523 2.6e-11 0.146 NA 0.203 NA 0.189 1.5e-11 NA 8.7e-16 NA 9.5e-15
6 GTEx Brain Cerebellar Hemisphere 0.4180 0.0790 3.2e-07 0.241 NA 0.229 NA 0.285 7.1e-07 NA 1.4e-06 NA 5.1e-08
7 GTEx Brain Cerebellum 0.4970 0.0900 6.3e-07 0.213 NA 0.188 NA 0.254 6.3e-07 NA 3.2e-06 NA 4.1e-08
8 GTEx Breast Mammary Tissue 0.1670 0.0660 2.3e-03 0.140 NA 0.083 NA 0.102 1.1e-07 NA 4.8e-05 NA 6.6e-06
9 GTEx Breast Mammary Tissue (Female) 0.3613 0.1449 1.4e-02 0.021 NA 0.001 NA 0.053 7.6e-02 NA 3.0e-01 NA 1.1e-02
10 GTEx Cells Transformed fibroblasts 0.3100 0.0530 1.8e-14 0.193 NA 0.235 NA 0.212 2.1e-14 NA 1.5e-17 NA 7.0e-16
11 GTEx Colon Transverse 0.1770 0.0530 1.7e-04 0.091 NA 0.034 NA 0.089 4.2e-05 NA 9.8e-03 NA 4.8e-05
12 GTEx Esophagus Muscularis 0.2000 0.0650 1.7e-04 0.037 NA 0.077 NA 0.103 2.5e-03 NA 2.1e-05 NA 8.7e-07
13 GTEx Heart Atrial Appendage 0.2290 0.0720 4.7e-04 0.001 NA -0.002 NA 0.007 3.0e-01 NA 4.3e-01 NA 1.4e-01
14 GTEx Heart Left Ventricle 0.3049 0.0661 6.1e-07 0.155 NA 0.143 NA 0.096 1.2e-08 NA 5.0e-08 NA 8.8e-06
15 GTEx Liver 0.5630 0.0790 3.1e-09 0.343 NA 0.492 NA 0.486 2.2e-10 NA 1.1e-15 NA 1.9e-15
16 GTEx Muscle Skeletal 0.2698 0.0411 0.0e+00 0.310 NA 0.329 NA 0.340 6.9e-31 NA 4.2e-33 NA 1.9e-34
17 GTEx Nerve Tibial 0.2616 0.0577 4.2e-10 0.186 NA 0.196 NA 0.183 3.6e-13 NA 6.6e-14 NA 5.8e-13
18 GTEx Ovary 0.2730 0.0900 2.8e-03 0.108 NA 0.084 NA 0.172 1.4e-03 NA 4.4e-03 NA 5.3e-05
19 GTEx Pancreas 0.4860 0.0630 0.0e+00 0.386 NA 0.432 NA 0.323 2.2e-17 NA 6.8e-20 NA 2.9e-14
20 GTEx Skin Not Sun Exposed Suprapubic 0.1110 0.0470 7.1e-03 0.005 NA -0.005 NA 0.027 1.5e-01 NA 9.4e-01 NA 1.2e-02
21 GTEx Skin Sun Exposed Lower leg 0.2110 0.0570 2.4e-05 0.032 NA 0.091 NA 0.078 1.1e-03 NA 6.0e-08 NA 5.0e-07
22 GTEx Stomach 0.1870 0.0530 1.4e-05 0.121 NA 0.118 NA 0.147 2.2e-06 NA 2.9e-06 NA 1.6e-07
23 GTEx Testis 0.4730 0.0600 0.0e+00 0.310 NA 0.363 NA 0.331 2.6e-14 NA 5.5e-17 NA 2.5e-15
24 GTEx Thyroid 0.1620 0.0520 1.9e-04 0.022 NA 0.079 NA 0.087 8.1e-03 NA 1.1e-06 NA 3.3e-07
25 METSIM Adipose 0.0885 0.0256 5.5e-08 0.057 0.060 0.061 0.063 0.064 5.6e-09 2.6e-09 1.6e-09 9.7e-10 6.8e-10
26 NTR Blood 0.1661 0.0231 0.0e+00 0.265 0.230 0.265 0.215 0.265 2.0e-85 1.2e-72 2.4e-85 2.2e-67 1.8e-85
27 YFS Blood 0.5241 0.0332 0.0e+00 0.515 0.596 0.619 0.495 0.606 9.2e-201 2.4e-250 7.1e-267 2.7e-189 2.3e-257
28 TCGA Cervical Squamous Cell Carcinoma 0.1570 0.0720 9.7e-03 0.000 0.028 0.015 NA 0.009 3.0e-01 1.5e-02 5.7e-02 NA 1.1e-01
29 TCGA Colon Adenocarcinoma 0.0960 0.0400 1.0e-05 0.163 0.058 0.122 NA 0.013 1.1e-09 2.9e-04 1.6e-07 NA 5.7e-02
30 TCGA Head and Neck Squamous Cell Carcinoma 0.0440 0.0213 7.2e-03 0.012 0.016 0.001 NA 0.004 1.6e-02 6.1e-03 2.1e-01 NA 1.0e-01
31 TCGA Kidney Renal Papillary Cell Carcinoma 0.0820 0.0320 2.1e-06 0.073 0.110 0.116 NA 0.106 5.5e-05 7.4e-07 3.8e-07 NA 1.2e-06
32 TCGA Brain Lower Grade Glioma 0.3572 0.0702 0.0e+00 0.347 0.354 0.369 NA 0.372 9.4e-41 8.0e-42 5.8e-44 NA 2.0e-44
33 TCGA Liver Hepatocellular Carcinoma 0.2800 0.0730 5.6e-17 0.274 0.317 0.373 NA 0.379 2.8e-13 1.7e-15 1.5e-18 NA 6.6e-19
34 TCGA Lung Adenocarcinoma 0.0729 0.0325 2.0e-03 0.016 0.029 0.027 NA 0.028 4.8e-03 2.1e-04 3.9e-04 NA 2.5e-04
35 TCGA Prostate Adenocarcinoma 0.1544 0.0514 0.0e+00 0.157 0.189 0.205 NA 0.208 4.0e-16 1.9e-19 4.7e-21 NA 2.1e-21
36 TCGA Soft Tissue Sarcoma 0.0690 0.0360 7.0e-03 -0.001 0.017 0.012 NA -0.004 3.9e-01 3.3e-02 6.3e-02 NA 6.3e-01
37 TCGA Thyroid Carcinoma 0.1190 0.0400 3.0e-08 0.085 0.104 0.097 NA 0.084 1.3e-08 2.8e-10 1.0e-09 NA 1.5e-08

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37
Bipolar Disorder (2018) 1.1 1.7 6.7 1.3 2.0 1.7 1.3 2.0 1.1 1.1 1.5 2.6 -0.7 -1.0 0.1 0.7 1.5 -1.7 1.0 1.9 0.9 -0.9 1.3 1.4 -1.0 1.8 0.2 1.1 1.5 1.8 1.0 -0.5 -0.1 -0.5 1.5 -0.9 1.3 -0.8 1.4 1.4
Bipolar Disorder or Schizophrenia 0.3 0.8 4.3 0.9 1.0 0.0 0.1 0.8 -0.1 -0.4 -0.3 0.8 0.9 0.3 0.0 -0.8 0.6 0.0 -0.4 0.1 0.8 0.6 0.5 2.0 0.5 -0.0 -0.1 0.2 -0.0 0.8 2.1 1.4 1.0 1.2 0.2 1.3 1.5 1.3 0.6 1.3
Depressed Affect (Nagel 2018) 2.0 4.2 8.0 -2.2 -1.8 -2.4 -2.0 -2.2 -2.0 -2.2 -2.1 -0.7 1.7 1.9 -1.4 -2.6 -2.7 2.5 -2.3 -2.2 -1.7 2.1 -2.4 -0.8 1.8 -2.8 -1.9 -2.1 -2.2 -2.4 -0.7 2.3 -0.7 1.9 -2.5 2.1 -1.4 2.2 -2.3 -2.3
Depression (Nagel 2018) 0.2 0.4 3.4 0.3 0.3 0.1 0.0 0.0 -0.3 -0.1 -0.6 -0.7 0.3 0.5 1.8 0.6 0.4 -0.0 0.1 0.5 0.3 0.3 0.5 0.6 0.7 -0.6 0.9 -0.1 -0.0 -0.4 0.5 0.5 1.4 -0.6 -0.0 0.5 1.1 0.4 -0.1 0.7
Intelligence (Savage-Jansen 2018) 1.3 4.1 7.6 -2.3 -1.9 -2.2 -2.1 -1.8 -2.1 -2.2 -2.1 -1.6 2.2 2.1 -1.7 -2.1 -2.2 2.2 -2.3 -2.8 -1.7 2.7 -1.8 -1.4 2.2 -2.3 -1.6 -2.2 -2.2 -2.0 -0.4 2.2 0.3 2.6 -2.3 2.2 -1.5 2.1 -1.4 -1.6
Neuroticism (Nagel 2018) 0.6 1.4 3.3 -1.0 -0.8 -1.6 -1.2 -1.0 -1.2 -1.2 -1.1 -0.9 1.0 1.0 -0.3 -1.5 -1.6 1.6 -1.4 -1.1 -0.8 1.6 -1.4 0.2 1.1 -1.8 -0.3 -0.9 -1.3 -1.4 0.2 1.6 0.0 1.0 -1.3 1.5 -0.1 1.4 -1.3 -1.1
Schizophrenia (2018) 0.7 1.5 4.5 -0.1 -0.3 -1.1 -0.8 -0.5 -1.0 -1.5 -1.5 -1.0 1.6 1.2 -0.0 -1.6 -0.2 1.2 -1.4 -1.5 -0.0 1.5 -0.5 1.4 1.4 -1.5 -0.6 -0.8 -0.9 -0.4 1.8 2.0 1.2 1.9 -0.8 2.1 0.8 2.0 -0.4 0.5
Schizophrenia vs Biploar Disorder 1.9 2.5 5.5 -1.3 -2.1 -1.3 -1.6 -0.5 -2.2 -1.9 -2.0 -0.8 1.6 2.2 -0.4 -1.4 -1.3 1.6 -2.0 -1.5 0.2 1.5 -1.4 -0.3 2.1 -1.3 -1.3 -1.8 -1.7 -1.4 0.6 1.5 0.9 2.2 -1.8 1.6 -1.4 1.7 -2.3 -1.8
Worry (Nagel 2018) 0.1 0.3 1.0 0.3 0.0 -0.6 -0.3 0.2 -0.2 -0.4 -0.2 -0.7 0.3 0.5 0.1 -0.8 -0.5 0.6 -0.4 0.2 0.3 0.9 -0.7 0.7 0.3 -0.8 0.2 0.1 -0.4 -0.2 1.0 0.6 -0.4 0.3 -0.2 0.8 0.7 0.7 -0.3 -0.1
Alzheimer’s Disease (in mother) 0.7 0.8 2.7 1.5 1.3 0.8 0.8 1.6 0.8 0.7 0.5 -0.1 -0.7 -0.8 0.7 0.7 0.9 -1.0 0.8 1.2 1.0 -1.1 0.6 0.5 -0.8 0.2 0.6 1.2 1.1 1.0 0.4 -0.7 0.2 -0.7 1.2 -0.7 0.5 -0.7 0.8 1.2
Alzheimer’s Disease (in father) 1.4 1.6 3.5 -1.1 -1.0 -1.1 -1.2 -1.2 -1.5 -1.6 -1.5 -1.7 1.4 1.6 -0.1 -0.9 -0.8 1.1 -1.4 -1.6 -0.2 1.5 -1.2 0.1 1.6 -1.9 -1.5 -1.3 -1.3 -0.9 0.5 1.6 0.9 1.6 -1.2 1.5 0.1 1.5 -0.8 -1.1
Alzheimer’s Disease (including proxy) 0.3 0.4 1.7 0.4 -0.1 0.1 -0.4 0.6 -0.7 -0.8 -0.7 -0.8 0.5 0.9 0.8 -0.2 0.2 0.1 -0.6 -0.2 0.9 0.2 -0.6 0.2 0.7 -1.0 -0.4 -0.2 0.1 0.2 1.1 0.8 1.3 0.8 0.2 0.6 0.5 0.8 -0.4 -0.1
Crohns Disease (2017) 0.5 1.1 3.4 -0.8 0.0 -1.4 -1.1 -0.9 -0.7 -1.1 -0.7 -0.8 0.7 0.6 -1.8 -1.7 -0.8 1.1 -1.0 -1.9 -1.0 0.6 -1.0 0.4 0.5 -1.5 -1.5 -0.7 -1.0 -0.4 0.0 1.5 -0.1 1.3 -1.0 1.3 0.3 1.3 0.1 -0.9
Irritable Bowel Disease (IBD) 0.2 0.6 2.5 -0.3 0.5 -1.0 -0.6 -1.2 -0.5 -0.6 -0.2 0.3 0.4 0.1 -1.5 -1.2 -0.6 0.4 -0.7 -1.0 -0.5 0.2 -0.6 0.8 0.0 -0.4 -1.1 -0.2 -1.0 0.2 0.5 1.6 0.1 0.9 -0.7 0.9 1.0 1.1 -0.0 -0.7
Ulcerative Colitis (UC) 0.2 0.3 1.7 0.1 0.4 -0.3 -0.2 -0.9 -0.3 -0.3 0.1 0.8 0.3 -0.1 -0.7 -0.4 -0.1 -0.2 -0.3 -0.0 0.1 0.1 -0.0 0.9 -0.1 0.6 -0.3 0.0 -0.7 0.5 1.0 1.3 0.6 0.4 -0.2 0.5 1.3 0.7 -0.0 -0.1
Major Depression (MDD) 0.2 0.2 1.9 0.4 0.5 0.5 0.2 0.6 0.2 0.1 0.7 1.4 -0.4 -0.0 -0.3 -0.1 -0.0 -0.6 0.0 0.3 0.2 -0.4 0.0 1.3 -0.6 0.7 -0.8 0.1 -0.1 0.4 0.8 0.1 -0.5 0.2 0.2 -0.3 0.2 -0.2 -0.2 -0.1
Reaction Time 0.7 1.3 4.4 0.0 0.1 -0.8 -1.0 -1.2 -1.0 -1.1 -1.1 -2.0 1.6 1.1 -0.5 -1.2 -0.8 0.9 -1.2 -1.2 0.3 1.3 0.3 1.0 1.7 -1.7 -0.4 -0.4 -1.2 -0.6 -0.2 2.1 0.6 1.2 -1.2 1.8 1.4 1.9 0.5 -0.1
Verbal and Numeric Reasoning (VNR) 1.2 2.9 6.1 -1.7 -1.4 -1.9 -2.0 -0.9 -1.6 -1.9 -1.7 -1.1 1.8 1.8 -2.0 -1.8 -2.0 1.8 -1.9 -2.5 -1.1 2.3 -1.1 -0.5 1.9 -1.9 -1.2 -2.0 -2.1 -1.7 -0.3 2.3 0.6 2.2 -2.1 2.1 -1.3 2.1 -0.8 -0.8
Breast Cancer 2.4 5.8 10.6 -2.6 -3.2 -2.3 -2.6 -2.0 -3.2 -2.9 -3.0 -1.7 2.7 3.0 -0.9 -2.1 -2.1 2.6 -3.0 -2.6 -0.8 2.7 -2.7 -2.5 2.8 -2.0 -1.6 -2.7 -2.3 -2.1 -0.3 2.1 1.2 2.7 -2.4 2.4 -1.6 2.4 -2.9 -2.7
Ovarian Cancer 0.4 0.5 2.3 -1.0 -0.5 -0.7 -0.5 -0.6 -0.8 -0.8 -0.9 -0.6 0.2 0.5 1.0 -0.3 -0.7 0.5 -0.5 -0.6 -0.7 0.8 -0.8 -0.8 0.4 -0.2 -0.5 -0.8 -0.5 -0.7 -0.8 0.6 1.4 0.4 -0.7 0.4 -0.5 0.4 -0.7 -1.5
Prostate Cancer 0.7 0.9 8.3 0.2 0.4 0.5 0.5 -0.2 0.6 0.7 1.0 2.9 -0.7 -0.6 -1.5 -0.1 -0.2 -0.7 0.5 0.7 -0.5 -1.1 -0.6 -0.4 -1.2 0.2 -0.3 0.2 1.1 0.5 -0.8 -1.3 -2.6 -0.4 0.9 -1.2 -0.6 -1.3 0.4 -0.2
Age at First Birth 0.7 1.0 4.3 0.1 -0.5 -0.4 -0.9 1.0 -1.1 -1.3 -1.4 -1.9 1.2 1.2 0.9 -0.1 -0.1 0.6 -1.1 0.2 0.6 1.2 -0.3 0.3 1.7 -0.4 -0.2 -0.6 -0.9 -0.6 2.1 1.2 1.7 1.0 -0.8 1.5 0.7 1.4 -0.6 0.4
Bipolar Disorder (2011) 0.2 0.2 1.7 -0.8 0.4 -0.6 -0.3 -0.1 0.4 0.1 0.2 0.2 -0.2 -0.4 -0.3 -0.6 0.2 0.1 0.1 -1.2 -1.3 -0.0 -0.2 -0.3 -0.3 -0.2 -0.5 -0.1 -0.2 -0.1 -1.2 0.5 -0.1 -0.2 -0.3 0.0 0.0 -0.0 0.3 -0.3
Body Mass Index (BMI) (2010) 0.2 0.2 0.7 0.4 0.4 0.4 0.5 0.4 0.4 0.6 0.6 0.5 -0.4 -0.6 -0.2 0.4 0.5 -0.5 0.5 0.9 0.5 -0.3 0.1 0.0 -0.7 0.5 0.1 0.5 0.6 0.6 -0.4 -0.7 -0.2 -0.5 0.6 -0.6 0.1 -0.5 0.0 -0.1
Coronary Artery Disease (CAD) 4.7 5.6 8.7 -2.8 -2.6 -2.2 -2.6 -2.8 -3.0 -2.8 -2.9 -2.1 2.9 2.7 -1.2 -1.9 -2.3 2.3 -2.7 -2.3 -1.6 2.7 -2.2 -2.4 2.6 -2.1 -1.6 -2.6 -2.6 -2.8 -0.9 2.0 0.7 2.6 -2.8 1.8 -1.7 2.0 -2.4 -2.6
Crohns Disease (2012) 0.2 0.3 1.6 0.2 0.8 0.3 0.3 0.1 0.6 0.3 0.5 -0.3 -0.7 -0.6 -1.2 -0.1 1.1 -0.4 0.4 -0.3 -0.3 -0.9 0.2 0.5 -0.7 -0.1 -0.1 0.6 0.7 0.7 -0.9 0.2 -0.4 0.1 0.4 -0.2 0.7 -0.1 1.3 0.3
Mean Putamen Volume 0.6 0.7 2.7 1.2 1.0 0.5 0.9 0.4 1.0 0.8 1.0 1.1 -0.8 -0.9 0.3 -0.3 0.2 -0.5 0.7 0.0 0.4 -0.4 0.7 1.6 -0.8 0.6 0.5 1.0 0.9 1.6 0.6 -0.4 -0.1 -0.6 1.2 -0.3 1.3 -0.5 0.9 0.9
Fasting Glucose 1.6 1.9 5.7 -1.8 -0.2 -2.0 -1.4 -1.7 -0.8 -1.3 -1.1 -0.9 0.2 0.7 -0.7 -2.1 -1.7 1.4 -1.1 -2.1 -2.4 1.1 -1.6 -1.0 0.7 -1.2 -2.0 -1.6 -1.4 -1.7 -0.6 1.9 -0.5 1.2 -1.6 1.1 -0.4 1.2 -1.2 -1.7
HbA1C 0.3 0.3 1.6 -0.1 1.1 0.1 0.3 0.4 0.5 0.5 0.7 -0.3 -0.9 -0.9 0.5 -0.0 0.2 -0.4 0.5 0.3 -1.1 -0.3 0.3 -0.0 -0.7 1.1 -0.5 0.2 0.4 0.1 -0.3 -0.3 -0.4 -0.8 0.3 -0.8 1.3 -0.6 0.7 -0.3
HDL Cholesterol 1.4 2.3 7.9 -1.4 -1.6 -1.7 -1.6 -1.1 -1.5 -1.1 -1.6 -0.9 1.6 1.2 -1.5 -1.1 -2.3 2.3 -1.5 -1.1 -0.1 1.3 -0.5 -0.9 1.5 -0.8 -1.1 -0.9 -2.1 -2.1 -2.2 0.6 -0.6 1.1 -2.3 1.4 -2.8 1.5 -1.5 -1.9
LDL Cholesterol 0.5 0.7 2.0 1.0 0.6 1.3 1.3 1.0 0.5 0.5 0.8 0.6 -0.7 -0.3 0.5 0.8 1.4 -1.2 0.6 1.2 1.0 -0.7 0.7 1.4 -0.4 0.6 1.3 0.7 0.8 1.0 0.9 -0.5 0.0 -0.2 0.8 -0.6 0.7 -0.6 0.7 1.3
Lupus 0.7 1.1 4.9 0.5 0.2 0.9 0.6 1.2 0.9 1.2 0.9 -0.5 -1.0 -0.8 2.1 2.2 0.2 -0.2 1.2 1.5 1.5 -1.0 1.4 0.2 -0.5 1.7 0.9 1.0 0.2 0.3 -0.3 -1.5 1.1 -1.9 0.4 -1.0 -0.3 -1.0 0.6 0.2
Neuroticism (2016) 0.1 0.2 0.9 -0.2 0.6 -0.4 0.1 -1.0 0.4 0.2 0.4 0.1 0.2 -0.6 -0.6 -0.4 -0.5 0.3 0.3 -0.3 -0.2 -0.2 0.1 0.9 -0.4 -0.5 -0.1 0.2 -0.2 0.3 -0.9 -0.0 -0.2 -0.1 -0.2 -0.1 -0.7 -0.0 0.1 -0.5
Primary Biliary Cirrhosis 0.4 0.6 3.3 -0.7 -0.5 -0.9 -0.8 0.5 -0.6 -0.8 -0.8 -1.8 0.4 0.6 -0.0 -0.4 -0.6 1.0 -0.6 -0.2 -0.0 1.1 -0.7 -0.2 0.6 -0.7 -0.7 -0.2 -0.9 -0.7 -1.1 0.8 0.2 0.7 -1.0 0.8 -0.3 0.9 -0.5 -1.2
Rheumatoid Arthritis 1.4 1.9 4.7 -1.0 -0.7 -1.1 -1.1 -1.6 -1.5 -1.5 -1.2 -0.4 1.9 1.4 -1.4 -2.2 -1.0 1.5 -1.8 -1.5 -0.5 1.5 -0.7 0.5 1.5 -1.5 -1.7 -1.3 -1.4 -1.0 0.6 2.1 -0.2 1.9 -1.6 1.9 -0.4 2.1 -1.6 -1.1
Schizophrenia (2014) 0.3 0.7 4.9 1.1 0.9 0.5 0.3 1.0 -0.2 -0.4 -0.4 0.5 0.6 0.4 1.0 -0.4 0.8 -0.1 -0.4 0.6 1.4 0.7 0.5 2.2 0.7 0.0 -0.1 0.2 0.6 0.9 1.9 0.6 1.2 1.0 0.6 0.8 1.7 0.7 0.2 0.5
Triglycerides 2.7 4.5 8.1 -1.3 -1.6 -2.2 -2.4 -1.7 -2.4 -2.7 -2.4 -0.5 2.5 2.6 -0.3 -2.4 -1.5 2.0 -2.5 -2.2 -1.0 2.6 -2.3 -1.1 2.3 -2.8 -1.7 -2.2 -2.1 -1.9 2.5 2.8 1.7 2.7 -2.0 2.6 0.6 2.6 -2.4 -1.4
Type 2 Diabetes (T2D) (2012) 1.1 1.2 3.3 0.8 1.8 0.9 1.0 0.8 1.7 1.3 1.4 0.8 -1.3 -1.8 0.4 0.5 0.8 -0.9 1.3 0.8 -0.1 -1.6 0.8 0.9 -1.5 1.5 0.2 1.4 1.4 1.3 -0.4 -1.0 -0.7 -0.9 1.2 -1.1 0.6 -1.2 1.1 0.5
Ulcerative Colitis 0.3 0.5 2.0 0.4 0.2 0.5 0.2 0.6 0.6 0.7 0.8 0.9 -0.8 -1.0 -0.1 1.1 0.3 -0.7 0.7 1.2 0.6 -1.0 0.6 0.2 -0.9 1.4 -0.5 0.9 -0.1 0.5 -0.8 -0.8 0.2 -1.0 0.2 -1.0 0.5 -0.8 0.5 -0.4
Blood Eosinophil Count 1.3 10.3 18.5 2.6 3.0 3.7 4.2 -0.1 3.9 3.9 4.1 3.9 -3.5 -3.9 -0.0 2.7 2.3 -3.6 3.4 3.6 0.6 -3.8 2.8 3.8 -4.3 1.2 0.3 3.1 4.0 3.7 -0.7 -3.9 -3.6 -3.0 3.7 -4.3 -0.4 -4.0 2.2 2.0
Blood Platelet Count 0.1 1.5 5.1 -1.1 -1.0 -0.9 -0.6 -1.9 -1.0 -0.9 -0.7 2.1 1.0 0.8 -1.5 -1.8 -1.9 0.8 -1.1 -1.5 -1.6 0.5 -1.3 -0.1 0.2 -2.1 -2.2 -1.4 -0.9 -1.1 -0.1 0.7 -1.1 1.1 -1.1 0.5 -0.9 0.5 -1.5 -1.6
Blood Red Count 0.0 0.4 5.1 0.6 0.7 0.0 0.3 -0.6 -0.2 -0.1 0.1 2.3 1.2 0.3 -1.1 -0.8 -0.9 -0.1 -0.4 0.5 0.7 0.5 0.0 0.3 -0.1 0.3 0.0 0.3 -0.1 0.7 -0.4 0.2 -0.5 0.5 -0.1 0.3 0.1 0.3 -0.2 0.1
Blood White Count 3.6 26.7 55.7 4.9 5.5 6.7 6.5 2.8 5.8 6.2 6.5 7.5 -5.2 -5.7 1.8 4.7 3.5 -5.9 5.6 6.0 3.1 -6.3 5.7 5.6 -5.7 4.5 2.2 5.0 6.0 5.9 -0.0 -5.7 -2.3 -5.5 5.8 -6.0 0.2 -5.7 3.7 4.3
Heel T-Score 0.1 0.7 5.6 1.3 0.2 1.1 0.7 -0.1 0.2 0.1 0.6 2.4 0.1 0.1 -1.1 -0.4 1.1 -0.9 -0.0 0.1 0.9 -0.3 0.2 0.8 0.0 0.5 0.1 0.2 1.1 0.8 1.8 0.2 -0.3 0.7 1.2 0.1 0.5 0.0 0.8 1.7
BMI 0.2 1.3 3.5 1.1 1.3 1.7 1.6 0.9 1.1 1.3 1.4 1.9 -0.7 -1.0 0.5 1.0 0.6 -1.4 1.1 1.7 1.0 -1.4 1.2 0.4 -1.3 1.7 -0.3 1.0 1.4 1.0 -0.6 -1.2 -0.8 -0.8 1.2 -1.4 -0.2 -1.2 0.4 0.3
Height 0.5 9.9 16.0 3.8 3.5 3.2 3.3 2.8 3.6 3.2 3.4 1.0 -3.6 -3.4 1.5 2.0 3.0 -3.6 3.6 3.2 2.1 -3.8 2.3 3.1 -3.6 3.2 3.3 3.7 3.9 3.8 0.3 -3.0 -0.3 -2.9 4.0 -3.3 2.5 -3.3 3.7 3.5
Waist Hip Ratio (WHR) 1.1 5.1 9.8 -2.2 -3.1 -2.1 -1.9 -2.7 -2.7 -2.2 -2.5 -2.0 2.8 2.5 -0.1 -2.2 -2.5 2.5 -2.5 -2.4 -0.9 2.0 -1.9 -1.8 2.7 -2.6 -1.5 -2.4 -2.5 -2.9 -0.1 1.7 0.6 1.9 -2.6 2.2 -1.8 2.1 -3.1 -2.8
Systolic Blood Pressure 0.5 2.5 9.9 1.8 0.1 2.1 1.7 1.5 1.0 1.5 1.3 1.6 -0.8 -0.9 2.0 2.4 1.6 -1.4 1.3 2.3 3.1 -1.9 1.2 0.2 -1.1 2.1 1.0 1.7 1.6 1.7 -0.7 -2.4 0.5 -1.8 1.7 -1.6 -0.5 -1.7 0.3 0.3
Smoking Status 0.3 0.7 1.9 -1.2 -0.4 -1.4 -0.9 -0.6 -0.6 -0.7 -1.1 -0.7 0.5 0.4 -0.1 -0.9 -0.8 0.5 -0.6 -0.8 -1.4 0.9 -0.9 -1.1 0.4 -0.8 -0.6 -1.0 -1.0 -1.1 -1.0 0.8 0.2 0.5 -1.1 0.4 -0.6 0.5 -1.0 -0.9
Allergy or Eczema 0.1 0.4 2.9 0.4 -0.9 -0.3 -0.4 0.1 0.1 -0.1 -0.2 -1.5 0.2 -0.0 0.6 0.0 0.7 0.6 0.1 -0.8 0.7 -0.2 -0.5 -0.5 -0.1 0.7 1.7 0.6 0.6 0.7 0.2 -0.1 1.1 -0.5 0.5 0.4 0.9 0.1 0.4 -0.0
Cardiovascular Disease 0.3 1.0 5.1 -1.9 -0.3 -1.2 -0.6 -1.1 -0.1 -0.4 -0.4 -0.0 0.3 -0.1 -0.1 -0.4 -1.1 0.7 -0.3 -1.4 -2.2 0.4 -0.9 -1.1 -0.2 -0.2 -1.7 -0.8 -0.9 -0.7 -2.2 0.7 -1.2 0.1 -1.2 0.1 -0.9 0.2 -0.7 -1.7
Hypothyroidism (self reported) 0.7 1.5 8.4 2.3 1.2 0.8 0.6 1.2 0.3 0.1 0.0 0.2 0.4 0.0 1.1 0.6 1.0 -0.7 0.3 1.6 1.9 0.5 0.9 2.1 0.2 -0.3 1.7 1.2 0.7 1.1 2.4 0.5 1.4 -0.1 1.1 0.6 2.9 0.6 1.5 2.2
Respiratory disease 0.6 1.3 3.7 1.2 0.8 1.1 1.4 -0.0 1.1 1.1 1.2 1.9 -1.4 -1.2 0.2 1.2 1.3 -1.2 1.1 1.3 0.7 -1.2 0.8 1.1 -1.4 0.4 1.1 1.2 1.2 1.5 0.0 -1.3 -1.1 -1.0 1.3 -1.4 0.3 -1.4 0.9 0.8
Type 2 Diabetes (T2D) (2018) 0.2 0.3 2.2 -1.1 -0.1 -0.1 -0.2 -0.1 -0.3 -0.2 -0.1 0.9 -0.0 0.1 -0.6 0.1 -1.1 -0.2 -0.1 -0.3 -1.5 0.4 -0.6 -0.6 -0.0 -0.1 -0.2 -0.9 -0.2 -0.7 -1.3 0.1 -0.5 0.3 -0.3 -0.4 -1.2 -0.3 0.0 -0.1
Lung FEV1/FVC ratio 0.2 1.1 3.3 -0.4 -0.8 -1.5 -1.0 -1.3 -1.3 -1.4 -1.6 0.3 1.7 1.1 -0.3 -0.1 -0.1 0.9 -1.0 -0.8 0.3 1.7 -1.2 -0.4 1.1 -1.8 0.1 -0.5 -1.6 -1.0 -0.9 1.5 0.2 1.0 -1.3 1.4 0.2 1.5 -0.1 -0.1
Lung FVC 0.4 2.0 5.1 -0.7 -1.0 -1.2 -1.2 -1.3 -1.7 -1.6 -1.5 -1.3 2.2 1.5 -1.2 -1.8 -0.9 1.5 -1.8 -1.3 0.2 1.6 -0.9 0.1 1.6 -1.1 -1.7 -1.3 -1.3 -0.8 2.3 1.7 0.8 1.7 -1.2 1.9 -0.3 1.9 -1.9 -0.9
Neuroticism 1.1 2.7 5.4 -1.4 -1.3 -2.0 -1.6 -1.7 -1.7 -1.8 -1.5 -1.0 1.7 1.6 -1.2 -2.3 -2.1 2.1 -1.9 -1.5 -1.0 1.9 -1.9 0.1 1.5 -2.1 -1.5 -1.5 -1.8 -1.7 0.4 1.9 -0.7 1.7 -1.9 2.0 -0.6 2.0 -1.8 -1.7
Chronotype (morning person) 0.2 0.3 3.3 -0.9 -0.5 -0.6 -0.7 -0.8 -0.2 -0.3 -0.6 -1.8 -0.0 0.1 -0.4 0.1 0.5 0.2 -0.1 -0.3 -0.9 0.4 -0.9 -0.7 0.0 -1.0 0.7 -0.4 0.0 -0.4 -1.4 -0.1 -0.0 -0.1 -0.2 -0.1 -0.3 -0.2 -0.0 -0.3
Hair Pigment 0.0 0.6 1.9 0.4 0.2 0.8 0.8 0.4 0.8 1.1 1.0 -0.3 -0.7 -0.8 0.3 0.8 0.5 -0.8 1.0 0.8 0.8 -1.3 0.8 0.2 0.1 1.0 0.5 1.0 0.7 0.5 -0.7 -1.4 0.1 -0.9 0.7 -1.1 -0.6 -1.2 0.2 0.4
Tanning 0.2 2.3 5.5 2.3 1.5 1.4 1.3 1.7 1.6 1.3 1.4 1.2 -1.3 -1.3 0.8 1.5 2.0 -1.6 1.6 1.3 1.5 -1.4 1.4 1.6 -1.3 1.4 1.9 1.9 1.4 1.6 1.1 -0.7 0.7 -1.4 1.7 -0.8 2.0 -0.8 2.3 2.4
Hand grip strength (left) 0.6 1.5 3.5 1.3 1.4 1.4 1.4 1.2 1.3 1.5 1.5 1.5 -0.6 -1.4 0.5 1.1 0.8 -1.0 1.3 1.5 1.5 -1.3 1.5 1.3 -1.4 1.9 0.2 1.5 1.3 1.8 -0.3 -1.4 0.8 -1.3 1.3 -1.2 -0.3 -1.2 0.4 0.6
Number of treatments/medications taken 0.2 0.4 4.2 -0.7 0.2 -0.6 -0.2 0.0 0.0 0.0 -0.2 -0.4 0.1 -0.2 1.5 -0.4 -1.1 0.4 0.0 -0.2 -0.8 0.2 -0.2 -0.6 -0.3 -0.6 -0.5 0.0 -0.5 -0.5 -1.5 0.2 0.4 -0.4 -0.6 -0.1 -0.4 0.0 -1.3 -2.0
Average weekly spirits intake 0.2 0.2 1.0 0.5 0.5 0.3 0.2 -0.2 0.1 0.3 0.7 0.5 -0.1 -0.2 0.1 -0.5 -1.0 -0.0 0.1 -0.2 0.5 -0.7 0.3 1.0 -0.2 -0.6 -0.5 0.2 -0.0 0.5 0.1 0.4 0.9 -0.0 0.1 0.1 -0.1 0.2 -0.3 -0.6
Sensitivity / hurt feelings 0.2 0.4 1.3 -0.5 -0.4 -0.9 -0.8 -0.6 0.0 -0.5 -0.4 -1.1 -0.0 0.0 0.5 -1.1 -0.3 1.0 -0.4 -0.9 -1.0 0.4 -0.6 0.0 0.1 -0.5 -0.2 -0.2 -0.2 -0.6 0.4 0.7 -0.0 0.2 -0.6 0.6 0.6 0.6 -0.6 -1.0
Frequency of depressed mood in last 2 weeks 0.1 0.2 1.0 0.6 0.5 0.2 0.2 -0.6 -0.2 -0.0 -0.1 0.4 0.6 0.3 0.7 -0.0 0.0 0.0 -0.0 1.0 0.5 0.0 0.0 1.0 0.1 -0.4 0.4 -0.0 -0.0 -0.3 0.9 0.5 0.0 0.0 -0.0 0.4 -0.3 0.5 -0.5 0.3
Hearing difficulty/problems: Yes 0.1 0.1 0.3 0.1 0.4 0.5 0.4 0.1 0.3 0.3 0.4 -0.3 -0.3 -0.4 -0.2 0.6 0.2 -0.4 0.5 0.3 0.2 -0.1 0.3 0.1 -0.5 -0.2 0.1 0.3 0.3 0.3 -0.5 -0.3 -0.0 -0.4 0.3 -0.4 -0.1 -0.3 0.4 -0.0
Relative age of first facial hair 1.2 2.4 6.2 -1.4 -0.9 -2.1 -1.5 -1.2 -1.5 -1.6 -1.7 -2.5 1.4 1.4 -0.2 -1.6 -1.1 1.9 -1.4 -1.7 -0.2 2.0 -1.4 -1.0 1.5 -2.2 -0.7 -1.2 -1.9 -1.5 -1.1 2.2 1.7 1.3 -1.8 2.0 -0.2 2.0 -1.2 -1.6
Other serious medical condition/disability diagnosed by doctor 0.5 0.7 5.7 -1.1 0.6 -0.4 -0.5 -0.9 0.4 0.2 0.5 0.6 -0.5 -0.7 -0.6 -0.2 -0.9 0.1 0.2 -0.2 -1.3 -0.1 -0.3 -1.0 -0.9 0.5 -1.5 -0.0 -0.3 -0.5 -2.4 0.2 -1.4 -0.4 -0.6 -0.5 -0.7 -0.2 -0.3 -1.7
Ever used hormone-replacement therapy (HRT) 1.1 1.4 4.1 -0.7 -0.5 -1.6 -1.3 -1.7 -1.0 -1.4 -1.4 -2.0 1.2 1.0 -0.4 -0.7 0.1 1.1 -1.2 -1.6 -0.6 1.4 -0.5 0.1 1.3 -1.9 -0.7 -0.8 -1.6 -0.9 0.5 2.0 0.5 1.1 -1.3 1.7 1.2 1.7 -0.1 -0.3
Ever had hysterectomy (womb removed) 0.4 0.5 2.4 -1.0 0.8 -1.0 -0.7 -1.0 0.0 -0.4 -0.1 -0.1 -0.7 0.0 -0.8 -0.5 -0.9 0.2 -0.1 -0.2 -1.5 0.7 -1.1 -1.2 -0.3 -0.8 -0.9 -0.5 -0.4 -0.5 -0.7 0.8 -0.9 0.2 -0.4 0.2 0.2 0.2 -0.1 -0.4
Systolic blood pressure, automated reading 1.6 4.6 9.4 2.4 1.7 2.8 2.5 1.6 2.0 2.3 2.2 2.4 -1.9 -1.9 1.6 2.5 1.7 -2.3 2.2 3.1 2.6 -2.7 1.9 0.7 -2.1 2.8 1.7 2.3 2.5 2.3 -0.7 -3.0 -0.1 -2.4 2.6 -2.5 -0.1 -2.5 0.9 1.2
Eye problems/disorders: Diabetes related eye disease 1.6 1.8 5.5 -2.0 -0.9 -1.0 -0.9 -1.7 -1.3 -1.2 -1.0 0.4 1.1 1.1 -1.1 -1.6 -1.7 1.1 -1.3 -1.9 -2.4 0.8 -1.4 -1.7 0.8 -1.4 -1.4 -1.7 -0.9 -1.5 -1.5 1.1 -1.2 1.3 -1.4 0.7 -1.0 0.7 -1.1 -2.0
Angina 4.3 5.6 10.0 -3.0 -1.8 -2.7 -2.3 -2.8 -2.2 -2.4 -2.1 -1.1 2.3 1.9 -1.2 -3.0 -3.1 2.4 -2.4 -3.2 -2.6 2.3 -2.6 -2.2 1.6 -2.8 -2.6 -2.6 -2.5 -2.5 -1.2 2.8 -0.1 2.4 -2.9 2.0 -1.1 2.2 -2.5 -3.1
Medication for hormone replacement therapy 1.2 1.4 2.9 0.7 1.1 1.3 1.4 -0.2 1.5 1.6 1.6 1.1 -1.4 -1.5 0.1 0.4 1.1 -1.2 1.3 0.6 0.5 -1.7 1.3 0.9 -1.5 0.7 0.1 1.4 1.6 1.4 -0.7 -1.5 -0.8 -1.3 1.3 -1.4 0.8 -1.4 0.7 -0.1
Vitamin and mineral supplements 0.9 1.3 4.0 0.8 2.0 1.0 1.3 0.1 1.2 1.1 1.3 1.5 -1.5 -1.4 -0.5 0.8 0.9 -1.4 1.1 1.2 -0.1 -1.2 1.1 1.3 -1.3 1.1 -0.3 1.2 1.0 0.9 -0.8 -0.6 -1.5 -0.8 1.0 -1.2 1.3 -1.0 1.5 0.5
Supplements: Zinc 0.2 0.3 3.0 0.7 -0.4 0.3 -0.2 0.7 0.1 -0.1 0.1 0.3 0.3 0.2 0.3 0.1 0.1 0.1 0.0 0.2 1.2 0.1 -0.1 0.1 0.0 0.5 0.9 -0.0 0.2 0.4 1.7 -0.1 0.8 0.2 0.4 0.3 -0.6 0.2 -0.0 0.9
Medication: Co-codamol 1.4 1.6 7.7 -1.8 -1.2 -1.0 -0.8 -0.7 -1.1 -0.8 -1.5 -2.8 1.1 0.7 2.6 0.5 -0.9 1.0 -0.4 -1.2 -1.4 1.1 -0.3 -1.7 1.0 -1.1 -0.1 -1.3 -0.9 -1.6 -0.7 0.6 2.8 -0.5 -1.1 0.5 0.0 0.4 -1.3 -1.3
Medication: Metformin 0.3 0.4 3.3 -0.8 0.2 0.1 0.1 -0.3 0.6 0.3 0.6 0.5 -0.8 -0.7 -0.5 -0.2 -0.7 -0.1 0.4 -0.8 -1.8 -0.5 -0.3 -0.1 -0.8 -0.1 -0.5 -0.2 0.3 -0.4 -1.4 -0.2 -1.5 -0.4 0.1 -0.7 -0.8 -0.7 0.4 -0.4
Diabetes (father) 0.3 0.4 1.9 0.4 0.9 0.7 0.6 0.4 0.2 0.4 0.4 -0.4 -0.2 -0.2 1.3 0.8 0.6 -0.8 0.5 1.4 0.8 -0.4 0.2 -0.2 -0.4 1.0 1.1 0.0 0.4 0.3 0.8 -0.4 0.9 -0.5 0.5 -0.5 -0.1 -0.4 -0.7 0.0
Diabetes (mother) 1.1 1.4 6.3 1.2 0.9 1.6 1.3 0.1 1.4 1.4 1.7 2.5 -1.2 -1.2 0.4 0.7 0.1 -0.8 1.1 0.8 0.6 -1.6 1.5 1.6 -1.3 1.4 1.3 1.2 1.2 1.1 0.0 -1.3 -0.8 -1.1 1.1 -1.3 -0.6 -1.1 0.6 0.5
Severe depression (siblings) 0.9 1.0 3.4 1.7 0.6 0.8 0.9 0.5 0.9 0.7 0.5 0.6 -0.6 -0.7 0.1 0.1 1.7 -0.9 0.9 0.0 0.8 -0.4 0.8 1.5 -0.6 0.6 1.4 0.9 1.5 1.4 1.6 -0.5 0.6 -0.5 1.4 -0.3 1.5 -0.5 1.1 1.9
Pack years adult smoking proportion 1.8 2.7 8.9 -2.4 -1.0 -1.4 -1.6 -1.1 -1.6 -1.5 -1.2 0.4 1.3 1.4 -1.3 -1.3 -1.9 1.4 -1.6 -1.1 -2.1 1.4 -1.7 -1.5 1.1 -1.8 -3.0 -2.2 -2.0 -2.3 -0.9 1.3 -1.0 1.5 -2.1 0.8 -2.2 1.1 -2.0 -2.2
Impedance of leg (right) 1.5 7.1 16.3 -2.5 -4.0 -2.9 -3.7 -1.6 -3.4 -3.3 -3.3 -2.2 2.1 3.2 -0.9 -2.0 -1.6 3.0 -3.0 -3.0 -0.6 2.7 -3.6 -4.0 3.0 -3.0 -0.9 -2.8 -2.7 -3.0 -0.1 2.1 1.7 2.4 -2.8 2.7 -1.3 2.5 -2.5 -2.8
Leg fat-free mass (left) 1.6 8.7 17.0 2.9 4.1 3.2 3.9 2.0 3.6 3.6 3.8 2.7 -2.6 -3.7 0.8 1.9 1.6 -3.3 3.3 3.1 1.2 -3.5 3.2 3.4 -3.8 3.4 1.2 3.3 3.3 3.3 -0.9 -2.9 -2.0 -2.7 3.3 -3.3 0.7 -3.2 2.4 2.3
Trunk fat percentage 0.7 2.7 6.3 1.5 2.3 2.2 2.0 1.0 1.8 2.0 2.1 2.0 -1.9 -1.8 0.9 1.4 0.4 -2.0 1.8 2.5 0.9 -2.0 1.9 0.9 -1.8 2.1 -0.1 1.4 1.8 1.2 -1.3 -1.9 -0.9 -1.4 1.6 -2.1 -0.6 -1.9 0.6 0.5
Hand grip strength (right) 0.3 0.9 3.6 1.2 0.7 1.2 1.0 1.1 0.7 1.0 0.9 1.0 -0.1 -0.7 0.3 1.0 0.9 -0.4 0.7 1.2 1.9 -1.0 1.4 1.2 -0.5 1.4 0.0 1.2 0.9 1.2 0.1 -1.0 1.0 -0.8 1.0 -0.6 -0.7 -0.6 0.3 0.7
Townsend deprivation index at recruitment 0.2 0.3 1.6 -0.4 -0.3 -0.7 -0.6 -0.3 -0.2 -0.6 -0.3 -0.6 0.1 0.1 0.6 -0.7 -0.1 0.3 -0.2 -1.1 -1.1 0.3 -1.3 -1.1 -0.3 -0.6 0.1 -0.6 -0.2 -0.8 -0.0 0.8 0.6 0.3 -0.4 0.2 0.1 0.3 -0.5 -0.7
Current tobacco smoking 0.3 0.4 1.5 -0.7 0.0 -1.2 -0.8 -0.2 -0.1 -0.4 -0.6 -1.2 0.3 -0.1 0.4 -0.7 -0.7 0.5 -0.1 -0.7 -0.8 0.5 -0.7 -1.1 -0.2 -0.4 -0.2 -0.3 -0.9 -0.6 -1.1 0.6 0.8 0.1 -0.8 0.3 -0.5 0.4 -0.6 -0.8
Average weekly fortified wine intake 0.0 0.1 0.6 -0.2 0.4 -0.2 -0.1 -0.5 -0.0 -0.1 0.1 0.1 0.2 -0.0 0.2 -0.2 -0.1 0.0 -0.0 0.0 0.1 -0.1 -0.3 -0.2 -0.2 0.3 -0.8 -0.0 -0.2 0.3 0.1 0.2 0.1 0.2 -0.1 0.1 0.2 0.1 -0.1 -0.4
Maternal smoking around birth 0.3 0.5 2.5 0.3 1.6 0.5 0.6 -0.3 0.8 0.7 0.8 -0.3 -0.9 -0.9 0.0 -0.2 0.3 -1.0 0.7 0.3 -0.7 -0.6 0.5 0.9 -0.9 0.7 0.1 0.4 0.9 0.9 -0.0 -0.1 -0.2 -0.1 0.9 -0.7 0.8 -0.7 0.5 0.5
Fed-up feelings 0.5 0.9 2.7 -0.7 0.3 -1.3 -0.8 -0.7 -0.7 -1.0 -0.8 -0.5 0.8 0.7 -0.9 -1.5 -1.3 1.2 -1.0 -0.7 -0.6 0.9 -1.1 0.4 0.6 -1.2 -0.6 -0.8 -1.2 -1.0 -0.5 1.7 -0.3 0.9 -1.4 1.2 -0.9 1.4 -1.1 -1.0
Frequency of unenthusiasm / disinterest in last 2 weeks 0.3 0.4 2.7 -0.4 0.9 -0.3 0.1 -0.7 0.3 0.1 -0.1 -1.4 -0.2 -0.5 1.6 -0.2 0.5 -0.0 0.3 -0.7 -1.2 0.0 0.3 0.2 -0.3 -0.4 0.4 -0.1 0.1 -0.3 -0.8 1.0 0.9 -0.6 -0.2 0.2 1.3 0.3 -0.0 -0.3
Relative age voice broke 0.3 0.4 2.0 0.2 0.4 -0.4 0.2 0.0 -0.2 -0.3 -0.4 -0.7 0.6 0.4 0.1 -0.7 0.7 0.3 -0.3 -0.4 0.5 0.8 0.2 1.4 0.6 -1.1 0.0 -0.1 -0.2 0.2 1.1 1.1 0.7 0.5 -0.0 1.0 1.1 0.9 -0.1 0.6
Taking other prescription medications 0.5 0.7 2.6 -0.6 1.0 0.4 0.5 0.6 0.9 0.9 1.0 0.2 -1.0 -1.0 0.8 0.3 -0.7 -0.6 0.8 0.7 -1.2 -0.4 0.2 -0.6 -1.3 0.5 -1.0 0.4 0.7 0.1 -1.6 -1.0 -0.9 -1.2 0.3 -1.3 -0.2 -1.2 -0.4 -1.5
Age when periods started (menarche) 0.1 0.2 1.1 0.3 -0.1 0.5 -0.2 0.1 -0.2 0.1 -0.1 0.4 0.0 0.0 0.6 1.1 -0.1 -0.1 0.2 0.7 0.8 -0.4 0.4 -0.3 -0.0 0.2 0.2 0.3 0.1 -0.1 -0.5 -0.4 0.8 -0.7 0.1 -0.3 -0.4 -0.2 -0.4 -0.4
Bilateral oophorectomy (both ovaries removed) 0.4 0.4 5.2 -0.4 0.7 -0.3 -0.1 -0.4 0.7 0.4 0.9 1.1 -0.6 -0.7 -1.2 -0.3 -0.5 0.2 0.2 -0.1 -0.7 -0.4 -0.3 -0.2 -0.9 0.2 -0.7 0.2 -0.3 0.0 -0.5 0.0 -2.3 -0.2 -0.3 -0.2 -0.9 -0.1 -0.1 -0.3
Heel bone mineral density (BMD) T-score, automated (left) 0.5 1.1 6.8 2.1 -0.1 0.9 0.6 1.4 0.0 0.2 0.3 1.6 0.8 0.2 0.2 -0.1 1.3 -0.3 -0.0 0.3 2.6 -0.5 0.9 1.6 0.2 0.5 1.7 0.7 0.4 0.8 2.3 0.1 1.3 0.3 1.0 0.6 0.6 0.6 0.3 1.5
Tinnitus: Yes, but not now, but have in the past 0.8 0.9 3.0 -1.1 -1.3 -0.4 -1.1 -1.2 -1.3 -1.0 -0.8 0.3 0.8 1.4 -0.2 -0.8 -1.4 0.8 -1.1 -0.7 -0.2 0.8 -0.8 -1.0 1.2 -0.3 -0.7 -1.1 -1.0 -0.8 -0.0 0.7 0.3 1.1 -1.1 0.6 -0.6 0.8 -1.3 -1.7
Qualifications: CSEs or equivalent 0.4 0.5 7.2 0.4 0.3 0.5 0.5 0.5 0.6 0.5 0.9 2.7 -0.3 -0.7 -0.7 -0.2 0.1 -0.7 0.4 -0.2 -0.4 -0.6 0.1 0.6 -1.0 1.3 -0.3 0.2 0.6 0.7 0.4 -0.1 -0.8 -0.3 0.6 -0.7 0.1 -0.5 0.2 0.3
Serious illness, injury or assault to yourself 0.5 0.6 2.2 -0.7 -0.5 -0.5 -0.8 -0.3 -0.6 -0.7 -0.2 0.6 0.4 0.5 -1.2 -1.3 -1.3 0.5 -0.8 -0.7 -0.4 0.3 -0.9 -0.7 0.0 0.1 -1.5 -0.6 -0.6 -0.4 0.0 0.5 -1.1 1.2 -0.7 0.3 -0.7 0.5 -1.1 -1.3
High blood pressure 0.4 1.2 3.6 0.5 1.4 0.7 1.2 0.4 1.5 1.2 1.2 0.4 -1.3 -1.6 1.7 0.9 0.6 -1.2 1.4 0.6 -0.4 -1.3 0.5 -0.0 -1.9 1.5 1.0 1.1 1.4 1.2 -0.4 -1.0 -0.1 -1.4 1.2 -1.4 0.4 -1.5 0.4 0.1
Hayfever, allergic rhinitis or eczema 0.2 0.4 2.6 0.7 -0.7 -0.2 -0.2 0.7 0.0 -0.1 -0.1 -1.5 0.4 0.1 0.4 -0.2 0.8 0.5 0.0 -0.6 1.1 -0.1 -0.2 -0.2 0.1 0.4 1.6 0.5 0.4 0.7 1.2 0.1 1.0 -0.1 0.5 0.6 0.6 0.4 0.1 0.5
Multivitamins +/- minerals 0.3 0.3 1.8 -0.5 -1.3 -0.5 -0.6 -0.1 -0.4 -0.3 -0.5 -0.4 0.5 0.6 1.0 -0.5 -0.6 0.6 -0.4 -0.7 -0.1 0.4 -0.7 -0.6 0.4 -0.7 0.4 -0.6 -0.1 -0.1 0.6 -0.3 0.6 0.1 -0.4 0.2 -0.7 0.0 -1.3 -0.9
Stomach or abdominal pain in last month 1.3 1.6 4.3 2.0 1.0 1.2 1.2 1.6 1.2 1.1 1.2 1.0 -0.7 -1.0 1.3 1.3 1.3 -0.8 1.3 1.2 2.1 -1.3 1.2 1.4 -1.1 0.8 2.0 1.6 1.0 1.4 1.5 -0.8 1.1 -1.2 1.4 -0.5 1.0 -0.5 1.0 1.5
Supplements: Glucosamine 2.0 2.7 10.0 -0.5 -1.9 -1.5 -1.7 -1.1 -2.0 -2.1 -2.6 -3.2 2.2 2.0 0.2 -0.8 -0.5 1.7 -1.9 -1.7 0.0 2.0 -1.2 -0.3 2.4 -1.8 -0.4 -1.1 -1.5 -1.3 1.5 2.1 1.7 1.8 -1.3 2.2 0.4 2.2 -0.8 0.4
Diverticular disease/diverticulitis (self-reported) 0.2 0.3 2.5 0.3 -1.0 0.1 -0.2 0.7 -0.5 -0.2 -0.4 -0.0 0.0 0.5 0.5 0.6 0.6 0.1 -0.1 0.3 1.4 0.1 -0.1 -0.7 0.4 0.1 0.9 0.0 -0.1 0.1 0.1 -0.4 1.6 -0.1 0.2 0.1 -0.3 0.0 -0.5 0.1
Medication: Atenolol 0.7 0.9 1.9 -0.3 -1.4 -0.8 -1.1 -1.2 -1.1 -1.1 -1.2 -0.4 0.8 1.2 0.3 -0.8 -0.7 0.9 -0.9 -0.5 0.4 0.8 -1.4 -1.3 1.0 -1.3 1.0 -0.6 -0.8 -0.6 -0.4 0.4 1.3 0.9 -0.9 0.9 -1.0 0.8 -1.1 -0.9
Medication: Levothyroxine sodium 1.0 1.7 5.9 2.0 2.2 1.0 1.2 1.2 1.3 1.1 1.0 0.4 -0.7 -1.3 1.1 0.7 1.2 -1.4 1.2 1.6 0.8 -0.6 1.1 1.9 -1.3 0.7 1.1 1.6 1.6 1.6 1.1 -0.4 0.3 -1.0 1.7 -0.7 2.4 -0.7 1.4 1.5
Sitting height 0.7 4.8 8.4 2.0 2.9 2.1 2.6 1.6 2.6 2.6 2.5 0.8 -2.7 -2.8 0.1 1.8 2.2 -2.4 2.6 2.2 0.6 -2.7 2.1 2.3 -2.7 2.2 1.2 2.5 2.3 2.4 -1.1 -2.2 -1.5 -2.4 2.4 -2.5 0.9 -2.4 2.5 1.9
Chronic bronchitis/emphysema (father) 2.4 2.8 10.9 2.4 0.1 1.5 1.3 2.1 1.1 1.2 0.7 -0.1 -1.6 -0.9 3.2 2.1 2.4 -1.0 1.4 1.4 2.9 -1.3 1.2 1.0 -0.6 0.8 3.3 1.9 1.8 1.7 2.2 -1.8 1.8 -1.5 1.8 -0.8 1.6 -1.2 0.6 1.6
High blood pressure (mother) 0.3 0.4 2.9 1.2 -0.5 0.2 0.4 0.9 0.2 0.2 0.3 1.4 0.4 -0.0 0.4 0.2 -0.1 0.2 0.1 0.6 1.7 0.0 0.3 0.9 -0.2 0.4 0.2 0.8 -0.1 0.5 1.3 -0.1 0.6 -0.2 0.3 0.3 -0.4 0.3 -0.1 0.9
Body mass index (BMI) 1.0 4.1 8.0 1.9 2.8 2.6 2.8 1.2 2.3 2.6 2.5 2.3 -1.5 -2.4 1.3 1.9 0.9 -2.4 2.3 2.5 1.2 -2.4 2.7 1.8 -2.3 2.5 0.3 2.0 2.2 2.0 -0.9 -2.1 -0.8 -1.8 2.1 -2.4 -0.1 -2.2 1.0 1.3
Impedance of leg (left) 1.0 4.9 11.8 -1.8 -3.3 -2.3 -3.3 -1.0 -2.8 -2.8 -2.9 -2.0 1.5 2.8 -0.2 -1.3 -1.0 2.5 -2.4 -2.2 -0.1 2.3 -2.8 -3.4 2.9 -2.3 -0.4 -2.3 -2.3 -2.5 0.2 1.9 2.2 1.8 -2.4 2.4 -0.7 2.3 -1.8 -2.0
Leg predicted mass (left) 1.6 8.7 17.1 2.9 4.1 3.2 3.9 2.0 3.6 3.6 3.8 2.7 -2.6 -3.8 0.7 1.9 1.5 -3.3 3.3 3.1 1.2 -3.5 3.1 3.4 -3.9 3.4 1.2 3.3 3.3 3.3 -0.9 -2.9 -2.0 -2.7 3.3 -3.3 0.7 -3.2 2.4 2.3
Trunk fat mass 1.4 6.1 11.6 2.2 3.4 3.1 3.1 1.5 2.9 3.1 3.2 2.8 -2.7 -3.0 1.1 1.9 1.0 -2.9 2.8 3.2 0.9 -3.1 2.6 1.7 -3.1 3.1 0.3 2.4 2.8 2.2 -1.5 -2.8 -1.6 -2.3 2.6 -3.2 -0.2 -2.9 1.3 1.1
Waist circumference 0.9 3.2 6.3 1.3 2.2 2.3 2.5 0.3 2.1 2.4 2.5 2.3 -1.4 -2.3 0.8 1.4 0.3 -2.0 2.0 2.0 0.6 -2.4 2.0 1.1 -2.4 2.1 0.1 1.7 2.0 1.5 -1.6 -2.2 -1.6 -1.7 1.8 -2.5 -0.9 -2.2 0.4 0.2
Number of incorrect matches in round 0.4 0.7 2.1 1.0 0.7 0.7 0.6 0.8 1.0 0.7 0.6 0.5 -1.4 -0.8 0.8 0.6 0.8 -0.7 0.8 0.8 0.5 -0.8 0.3 0.3 -0.8 0.3 1.1 1.2 1.2 0.8 -0.1 -1.0 -0.3 -0.9 1.0 -0.7 1.3 -0.9 1.0 0.3
Past tobacco smoking 0.2 0.3 2.1 0.0 -0.5 -0.6 -0.4 0.5 -0.3 -0.4 -0.5 -1.3 0.6 0.3 0.5 0.1 -0.1 0.8 -0.2 -0.8 0.5 0.3 -0.1 -0.7 0.4 -0.1 0.3 0.2 -0.6 -0.2 -0.3 0.7 1.4 0.2 -0.5 0.8 -0.0 0.8 0.2 -0.2
Alcohol usually taken with meals 0.4 0.7 3.6 0.6 1.1 -0.2 0.3 0.9 1.1 0.6 0.7 -0.0 -0.5 -1.0 -0.2 0.5 0.8 -0.3 0.9 0.1 -0.5 0.0 0.1 0.6 -1.1 0.6 1.2 1.0 0.9 1.3 0.9 -0.3 -0.0 -0.8 0.9 -0.3 1.9 -0.6 1.7 1.3
Nervous feelings 0.6 1.0 2.8 1.5 1.2 0.7 1.0 1.5 1.2 1.1 1.1 -0.4 -0.6 -0.8 1.3 0.4 0.5 -0.7 1.0 1.7 0.6 -0.6 0.9 1.1 -1.0 1.0 1.4 1.3 1.0 0.9 0.9 -0.8 -0.2 -1.3 1.2 -0.6 1.4 -0.7 0.9 0.9
Frequency of tenseness / restlessness in last 2 weeks 0.1 0.2 1.0 -0.1 0.1 -0.2 -0.1 -0.7 -0.5 -0.4 -0.3 -0.3 0.7 0.2 0.4 -0.3 0.1 -0.1 -0.3 0.1 -0.0 0.2 -0.7 0.1 -0.1 -0.8 -0.3 -0.5 -0.1 -0.2 0.5 0.6 0.2 0.5 -0.2 0.3 -0.2 0.4 -1.0 -0.6
Hearing difficulty/problems with background noise 0.1 0.1 0.4 -0.3 -0.2 -0.2 0.0 -0.6 -0.3 -0.2 -0.1 -0.6 0.6 0.3 -0.6 -0.4 -0.6 0.4 -0.3 -0.2 -0.3 0.6 0.1 0.6 0.1 -0.4 -0.4 -0.3 -0.4 -0.2 0.2 0.2 -0.6 0.3 -0.4 0.3 -0.3 0.3 -0.1 -0.1
Hair/balding pattern: Pattern 2 0.6 0.8 6.5 -1.0 -0.3 -0.1 -0.3 -1.1 -0.1 0.2 0.2 0.8 -0.1 -0.3 -1.4 0.2 -1.5 0.4 0.0 0.1 -0.8 -0.6 -0.4 -1.8 -0.5 0.2 -0.5 -0.2 -0.3 -0.8 -2.5 -0.8 -1.8 -0.5 -0.5 -0.8 -1.6 -0.6 -0.4 -1.3
Had menopause 0.6 0.7 2.3 -0.6 -0.3 -1.0 -1.3 -1.0 -1.0 -1.2 -1.3 -1.5 0.3 1.0 -0.5 -0.5 -0.7 0.6 -0.9 -0.3 -0.5 1.1 -1.4 -1.0 0.9 -1.5 -0.4 -0.5 -0.7 -1.0 -0.4 0.9 0.1 0.8 -0.7 0.7 0.2 0.7 -0.2 -0.3
Had other major operations 0.2 0.3 0.9 0.2 0.4 0.6 0.4 0.2 0.6 0.6 0.8 0.3 -0.6 -0.7 0.4 0.1 -0.0 -0.7 0.6 0.1 -0.1 -0.6 0.1 -0.2 -0.8 1.0 -0.2 0.2 0.6 0.7 0.0 -0.4 -0.6 -0.7 0.6 -0.7 0.2 -0.7 -0.3 -0.3
Forced vital capacity (FVC) 0.3 1.2 4.0 -1.5 -0.8 -1.4 -1.1 -0.9 -0.8 -0.8 -0.5 -1.1 0.7 0.6 -2.0 -1.2 -1.3 1.5 -0.9 -1.2 -1.3 0.8 -1.0 -0.7 0.5 -0.6 -1.9 -1.1 -1.5 -1.3 -0.1 0.6 -0.8 0.8 -1.4 0.7 -1.6 0.8 -1.0 -1.5
Heel bone mineral density (BMD) T-score, automated (right) 0.3 0.6 3.7 1.5 0.1 0.8 0.6 1.4 0.2 0.3 0.5 1.9 0.4 0.0 -0.3 0.0 0.9 -0.3 0.1 0.3 1.9 -0.5 0.6 1.0 -0.1 0.4 1.2 0.6 0.5 0.7 1.4 -0.1 0.3 0.2 0.8 0.2 0.5 0.2 0.6 1.0
Ever unenthusiastic/disinterested for a whole week 0.4 0.5 3.4 0.5 0.7 1.2 0.5 0.9 0.4 0.5 1.0 1.8 -0.8 -0.1 0.1 0.7 0.8 -1.0 0.3 1.2 0.5 -0.6 0.1 0.5 -0.7 1.0 -1.1 0.2 0.6 0.6 0.7 -0.5 -0.7 -0.3 0.7 -0.8 0.1 -0.6 0.0 0.5
Qualifications: None of the above 0.8 1.6 5.7 0.6 2.4 1.8 2.0 -0.5 1.5 1.6 1.6 1.4 -1.3 -1.7 0.7 0.5 0.4 -1.5 1.3 1.5 -0.7 -1.5 1.6 1.6 -1.6 0.3 -0.4 0.7 1.7 1.1 0.1 -1.0 -1.4 -1.0 1.3 -1.6 -0.7 -1.4 -0.2 0.4
Financial difficulties in last 2 years 0.3 0.3 3.1 -0.8 -0.5 -0.7 -0.1 -0.1 0.1 0.1 -0.4 -1.1 -0.3 -0.1 1.8 0.3 -0.4 0.6 0.3 -0.9 -1.1 0.2 0.2 -0.2 0.1 -0.2 0.1 -0.5 -0.6 -1.0 0.3 -0.2 0.8 -0.7 -0.7 -0.0 -0.6 -0.1 -0.5 -0.3
Mouth/teeth dental problems 2.0 3.1 8.0 2.0 1.1 1.7 1.9 1.5 2.1 2.0 2.1 2.0 -1.7 -2.1 0.3 1.3 1.5 -1.4 1.9 0.8 1.4 -1.7 2.0 2.8 -1.8 1.5 2.2 2.2 1.9 2.4 0.5 -1.5 0.0 -2.1 2.0 -1.4 1.3 -1.4 2.1 1.9
Heart attack 0.7 0.9 2.5 -0.6 -0.2 -1.4 -1.1 -1.4 -0.6 -1.1 -1.1 -1.3 0.7 0.7 0.1 -0.9 -0.9 1.1 -0.8 -1.2 -0.5 1.2 -1.0 -0.5 0.7 -1.5 -0.2 -0.5 -0.9 -0.4 -0.1 1.6 1.2 1.0 -0.9 1.3 0.6 1.3 -0.4 -0.6
Allergy 0.3 0.8 3.0 -1.0 -0.4 -0.7 -0.7 -0.8 -1.0 -0.7 -0.9 0.2 0.9 0.8 -0.5 -0.6 -1.4 0.7 -0.9 -0.4 -0.4 1.0 -0.2 -0.4 1.0 -0.8 -1.7 -0.8 -1.2 -1.4 -1.2 0.8 0.2 0.8 -1.2 0.6 -1.1 0.8 -0.9 -1.2
Pain all over the body in last month 0.3 0.3 1.7 0.6 0.2 0.2 0.6 0.4 0.5 0.5 0.4 -0.8 -0.1 -0.7 1.3 0.2 0.8 -0.0 0.4 -0.0 0.8 -0.8 0.5 0.8 -0.4 0.1 0.5 0.7 0.3 0.7 0.5 -0.3 0.5 -0.7 0.3 -0.2 0.8 -0.1 0.2 -0.0
Diabetes (self-reported) 0.5 0.8 2.8 -1.3 -0.5 -0.7 -0.8 -1.0 -0.8 -0.9 -0.8 -0.7 0.8 0.8 -1.2 -0.7 -1.4 0.7 -0.8 -0.7 -1.7 1.2 -0.7 -0.6 0.8 -0.9 -0.3 -1.2 -0.8 -1.2 -0.7 1.0 -0.8 1.1 -0.9 0.7 -1.0 0.8 -0.1 -0.5
Hayfever/allergic rhinitis (self-reported) 1.6 2.1 4.6 1.3 0.9 1.4 1.2 1.8 1.6 1.8 2.0 1.4 -1.5 -1.4 0.3 1.3 0.8 -1.1 1.6 2.0 1.0 -1.5 0.8 -0.6 -2.0 2.0 1.3 1.6 1.7 1.4 -0.8 -2.1 -1.4 -1.8 1.5 -1.7 0.2 -1.7 0.5 -0.6
Medication: Ramipril 0.7 0.9 2.2 -1.1 -0.7 -0.7 -0.8 -1.1 -0.9 -1.0 -1.0 -0.4 0.9 0.8 -0.4 -0.9 -1.1 0.9 -1.0 -0.9 -1.0 0.9 -0.8 -1.0 0.8 -0.9 -1.2 -1.3 -0.7 -1.2 0.4 0.9 -0.2 1.1 -0.9 0.8 -1.2 0.8 -1.5 -1.0
Medication: Simvastatin 1.0 1.5 4.0 -1.3 0.0 -1.1 -1.0 -1.3 -1.1 -1.4 -1.3 -1.0 1.3 1.1 0.6 -1.3 -1.7 0.9 -1.2 -1.0 -1.5 1.9 -0.9 0.2 1.2 -1.6 -0.9 -1.6 -1.1 -1.2 0.5 2.0 0.8 1.3 -1.4 1.3 -0.4 1.5 -1.5 -0.6
Fluid intelligence score 1.0 2.1 8.7 -1.7 -1.8 -1.8 -1.6 -1.0 -1.1 -1.4 -1.4 -1.1 1.5 1.1 -2.0 -1.6 -1.3 1.8 -1.5 -2.9 -1.5 1.6 -0.9 -0.4 1.5 -1.2 -1.2 -1.5 -1.6 -1.5 -1.5 1.6 0.1 1.6 -1.7 1.6 -1.0 1.4 -0.1 -0.7
Illnesses of siblings 0.1 0.2 1.4 -0.0 0.6 0.1 0.2 0.5 0.4 0.3 0.5 -0.1 -0.2 -0.3 -1.2 -0.1 -0.1 -0.2 0.2 0.3 -0.1 0.1 0.1 0.4 -0.5 -0.1 0.3 0.3 0.3 0.5 -0.5 -0.1 -0.6 -0.1 0.3 -0.2 0.3 -0.2 0.9 0.4
Neuroticism score 0.3 0.7 2.4 -0.1 -0.0 -0.9 -0.6 -0.5 -0.7 -0.9 -0.6 -0.7 0.9 0.8 -0.0 -1.3 -0.7 0.9 -0.9 -0.5 -0.1 1.1 -0.7 1.2 0.8 -1.0 -0.2 -0.5 -0.8 -0.7 1.1 1.5 0.3 0.8 -0.7 1.3 0.5 1.4 -0.6 -0.3
Weight 1.9 9.3 16.6 3.0 4.1 3.6 3.9 2.0 3.7 3.8 3.9 2.8 -2.9 -3.7 1.4 2.5 1.7 -3.4 3.5 3.4 1.5 -3.8 3.4 2.8 -3.8 3.5 1.1 3.3 3.5 3.2 -1.2 -3.3 -1.5 -3.0 3.4 -3.6 0.5 -3.4 2.2 2.1
Impedance of arm (right) 0.5 2.2 6.0 -1.4 -2.5 -1.4 -2.1 -0.6 -1.7 -1.7 -1.8 -2.0 0.5 1.8 -0.1 -0.8 -0.8 1.7 -1.6 -1.2 -0.6 1.6 -1.7 -1.9 2.0 -2.0 -1.1 -1.5 -1.5 -2.1 -0.5 1.0 0.7 1.1 -1.6 1.4 -1.0 1.4 -1.1 -1.6
Arm fat percentage (right) 0.7 2.8 5.5 1.5 2.2 2.3 2.3 0.8 1.9 2.2 2.1 1.9 -1.6 -1.9 1.4 1.6 0.4 -2.0 1.8 2.3 0.9 -2.0 2.3 1.3 -1.7 1.9 -0.3 1.6 1.9 1.3 -1.3 -2.0 -0.6 -1.5 1.7 -2.1 -0.6 -1.9 0.5 0.6
Trunk fat-free mass 1.5 8.7 16.6 2.7 3.9 3.0 3.7 1.8 3.7 3.6 3.8 2.3 -2.7 -3.9 0.8 2.0 1.7 -3.2 3.5 2.5 0.9 -3.7 2.9 3.0 -4.1 3.1 1.6 3.5 3.4 3.5 -1.2 -3.1 -2.0 -3.0 3.3 -3.4 1.2 -3.3 2.7 2.1
Hip circumference 2.3 9.9 16.2 2.9 4.0 3.7 3.9 2.1 3.8 3.9 4.0 3.2 -3.1 -3.8 1.2 3.0 1.8 -3.6 3.6 3.8 1.4 -3.6 3.4 2.5 -3.9 3.8 1.2 3.4 3.5 3.2 -1.5 -3.5 -1.8 -3.2 3.4 -3.8 0.2 -3.6 2.4 2.2
Time employed in main current job 0.4 0.5 2.2 0.2 -0.6 -0.6 -0.6 0.4 -0.9 -0.8 -1.0 -0.9 0.6 0.8 0.3 -0.7 -0.3 0.6 -0.8 -0.8 0.8 0.6 -0.4 -0.1 1.1 -0.5 -0.0 -0.2 -0.5 -0.2 1.0 0.5 1.5 0.8 -0.4 0.9 0.6 0.7 -0.5 -0.2
Alcohol intake versus 10 years previously 1.8 2.8 5.7 -2.2 -1.0 -1.9 -1.8 -0.9 -1.4 -1.7 -1.4 -1.1 1.0 1.4 -1.3 -1.9 -2.4 1.6 -1.6 -2.1 -2.3 1.9 -2.0 -1.4 1.0 -1.7 -2.0 -2.1 -1.9 -2.0 -0.1 2.0 -0.3 1.8 -2.0 1.4 -1.8 1.5 -1.5 -1.0
Father’s age at death 0.4 0.6 2.5 0.5 -1.1 0.4 0.2 1.6 0.1 0.2 -0.2 -1.2 -0.0 0.1 1.1 1.4 0.9 -0.2 0.5 0.5 1.2 -0.1 0.5 -0.4 0.3 0.7 1.6 0.5 0.3 0.2 0.7 -0.8 1.3 -0.7 0.4 -0.2 0.3 -0.4 0.8 1.3
Worrier / anxious feelings 0.2 0.5 2.1 -0.0 -0.2 -0.7 -0.7 0.1 -0.6 -0.9 -0.9 -1.5 0.4 0.8 0.2 -0.5 -0.2 0.5 -0.6 0.0 0.2 1.1 -0.6 0.7 0.8 -0.1 0.2 -0.2 -0.7 -0.2 1.2 1.1 0.9 0.7 -0.4 1.0 1.0 1.0 0.1 0.2
Frequency of tiredness / lethargy in last 2 weeks 0.2 0.4 2.6 -0.5 0.2 -0.6 -0.4 -0.4 0.4 0.2 0.5 -0.5 -0.1 -0.8 0.1 -0.6 -0.9 0.6 0.3 -0.7 -1.0 -0.3 -0.4 -0.6 -1.0 0.3 -0.2 0.3 -0.3 -0.4 -1.6 0.2 -0.7 -0.5 -0.6 -0.2 -0.3 0.0 -0.4 -1.6
Falls in the last year 0.7 1.0 4.6 0.5 0.8 1.6 1.5 0.2 0.6 1.1 1.3 2.1 -0.9 -0.7 1.1 0.7 -0.4 -1.4 0.9 1.3 0.6 -1.2 1.0 0.5 -0.8 1.2 -0.7 0.4 0.9 0.6 0.1 -1.3 -0.4 -0.8 0.9 -1.5 -0.6 -1.4 -0.5 -0.1
Hair/balding pattern: Pattern 3 0.5 0.7 4.6 1.4 -0.3 0.0 0.3 0.5 -0.0 -0.1 -0.2 -1.1 0.3 0.2 1.4 0.0 0.9 -0.1 0.0 0.1 1.5 0.5 0.0 1.1 0.3 -0.0 1.5 0.7 0.2 0.4 2.1 0.3 1.8 -0.0 0.5 0.7 1.6 0.4 0.4 1.2
Number of live births 1.4 2.0 5.3 0.7 1.3 1.2 1.6 0.1 1.8 1.8 1.9 1.7 -1.4 -2.2 -0.4 0.9 0.7 -1.3 1.6 0.7 -0.1 -1.9 1.2 0.8 -2.2 0.9 0.1 1.6 1.4 1.5 -2.3 -1.5 -2.3 -1.4 1.2 -1.9 0.2 -1.7 1.4 -0.1
Forced expiratory volume in 1-second (FEV1) 0.5 1.7 3.9 -1.5 -0.8 -1.7 -1.4 -1.4 -1.2 -1.3 -0.9 -0.5 1.5 1.1 -2.0 -1.4 -1.4 1.7 -1.3 -1.4 -1.1 1.4 -1.4 -0.8 0.9 -1.1 -1.7 -1.4 -1.9 -1.4 0.2 1.3 -0.5 1.2 -1.7 1.3 -1.3 1.4 -1.0 -1.4
Pulse rate 0.2 0.3 2.2 -0.3 1.0 0.0 0.2 -0.3 -0.4 -0.3 -0.3 -0.1 0.5 0.6 0.1 0.1 -0.2 -0.5 -0.3 0.3 -1.1 0.7 0.3 0.5 0.7 -0.1 -0.9 -0.9 -0.7 -0.6 1.5 0.7 0.4 0.5 -0.3 0.3 -0.2 0.4 -0.1 0.9
Happiness 0.4 0.5 1.7 0.1 1.2 0.3 0.7 -1.0 0.8 0.7 0.6 -1.1 -0.5 -0.9 1.3 0.6 0.9 -0.6 0.7 0.0 -0.8 -0.6 0.7 1.1 -0.8 -0.0 -0.4 0.2 0.7 0.5 0.9 -0.1 0.3 -0.9 0.5 -0.6 1.1 -0.6 0.2 0.6
Noisy workplace 0.5 0.6 1.7 -0.2 1.0 0.9 0.6 -0.2 0.7 0.9 0.8 0.1 -1.0 -0.7 0.2 1.3 0.2 -0.9 0.9 1.3 -0.9 -1.2 0.9 -0.1 -0.7 1.0 0.6 0.3 0.6 0.1 -1.3 -0.9 -0.7 -0.9 0.4 -1.3 -0.2 -1.2 0.7 -0.1
Qualifications: A levels/AS levels or equivalent 0.5 1.0 2.9 -1.2 -1.1 -1.3 -1.3 -0.5 -0.8 -0.9 -0.8 -0.9 0.8 1.1 -0.7 -0.7 -0.9 1.3 -1.0 -1.7 -0.8 0.9 -0.6 -0.9 1.3 -1.2 -1.0 -1.2 -1.6 -1.2 -0.5 0.9 -0.6 1.1 -1.4 1.1 -0.4 1.0 -0.0 -0.6
Serious illness, injury or assault of a close relative in last 2 years 1.7 1.9 3.6 -1.6 -1.4 -1.4 -1.5 -0.7 -1.5 -1.6 -1.1 -0.8 1.6 1.6 -1.4 -1.3 -1.3 1.5 -1.5 -1.2 -0.8 1.6 -1.4 -1.4 1.5 -0.7 -1.1 -1.7 -1.9 -1.5 0.0 1.5 0.1 1.8 -1.7 1.5 -1.2 1.5 -1.0 -1.5
Mouth/teeth dental problems: Dentures 0.5 0.8 3.9 -0.6 1.0 0.5 0.3 0.0 0.5 0.6 0.3 -0.4 -1.3 -0.6 0.6 0.7 0.1 -1.2 0.7 1.3 -1.6 -0.6 -0.4 -2.0 -1.1 0.7 -0.6 -0.1 1.1 -0.1 -1.7 -1.1 -0.9 -0.5 0.6 -1.7 -0.9 -1.6 -0.3 -0.4
Asthma 0.4 0.8 6.3 1.3 0.4 1.1 1.2 0.3 0.8 0.7 1.1 2.5 -0.7 -0.6 -0.4 -0.2 0.6 -0.7 0.4 0.6 1.0 -0.8 0.7 1.6 -0.8 0.1 0.4 0.7 1.0 1.4 1.4 -0.6 -1.4 -0.1 1.0 -0.6 0.2 -0.5 0.3 0.7
Medication: Ibuprofen (e.g. Nurofen) 0.8 1.0 5.5 1.9 0.9 1.1 0.8 1.1 0.4 0.7 0.5 1.3 -0.3 -0.3 0.8 0.5 0.3 -0.6 0.5 1.6 2.3 -0.5 1.3 1.3 -0.1 1.0 1.4 1.1 0.9 1.3 1.2 -0.5 1.0 -0.4 1.1 -0.1 0.7 -0.1 0.1 1.1
Medication: Cholesterol lowering 0.7 1.1 3.7 -1.6 -0.2 -1.5 -1.1 -1.4 -0.5 -0.9 -0.9 -1.0 0.1 0.3 -0.1 -1.1 -1.9 1.1 -0.6 -1.5 -1.9 1.6 -1.2 -0.4 0.4 -1.4 -0.5 -0.9 -0.9 -0.9 -1.0 1.5 0.1 0.7 -1.2 0.8 -0.5 0.9 -0.7 -1.0
Depression (self-reported) 1.4 1.6 3.5 -1.4 -1.7 -1.1 -1.1 -1.0 -1.7 -1.2 -1.5 -1.3 1.4 1.5 -0.0 -0.9 -1.8 1.2 -1.3 -0.7 -0.2 1.7 -0.8 -1.1 1.6 -1.2 -1.2 -1.1 -1.5 -1.5 -1.6 1.0 0.8 1.1 -1.6 1.1 -0.8 1.1 -1.3 -1.9
Medication: Lansoprazole 1.1 1.2 3.7 -0.7 0.8 0.9 1.1 0.2 1.3 1.4 1.5 0.8 -1.3 -1.4 0.6 1.2 0.4 -0.9 1.3 0.7 -1.0 -1.1 0.6 -0.3 -1.7 0.7 0.2 0.4 1.0 0.3 -1.9 -1.6 -1.2 -1.4 0.6 -1.9 -1.4 -1.8 -0.3 -0.9
Prospective memory result 0.7 0.8 3.5 0.7 0.5 0.7 1.0 0.5 0.6 0.7 0.4 -1.4 -0.6 -0.9 1.9 1.5 1.4 -1.0 1.1 1.2 0.3 -0.7 0.3 0.2 -0.8 0.3 1.1 1.2 0.8 0.5 -0.6 -1.1 0.2 -1.2 0.8 -0.9 1.2 -0.9 0.8 0.4
Lung cancer (father) 2.4 2.8 10.3 2.6 0.7 1.8 1.7 2.2 1.5 1.7 1.3 0.6 -1.3 -1.4 1.6 1.9 2.3 -1.1 1.7 1.8 3.2 -1.9 1.7 1.2 -1.2 1.0 1.6 2.3 1.8 1.8 0.5 -2.3 1.0 -1.8 1.9 -1.2 -0.1 -1.4 1.0 1.5
Illnesses of mother 0.4 0.5 2.9 -1.1 0.1 -0.7 -0.6 -1.2 -0.4 -0.4 -0.4 -1.3 -0.1 0.1 -0.3 -0.2 0.8 -0.2 -0.2 -0.6 -1.7 0.3 -1.1 -1.2 -0.2 -0.9 -0.2 -0.5 -0.1 -0.5 -1.4 0.3 -0.7 0.1 -0.4 -0.3 1.0 -0.2 0.1 -1.1
Forced expiratory volume in 1-second (FEV1), Best measure 0.2 0.6 1.8 -0.7 -0.3 -1.1 -0.8 -0.3 -0.8 -0.8 -0.7 -0.6 1.1 0.6 -0.4 -0.5 -0.4 1.1 -0.7 -0.7 -0.3 0.8 -0.6 -0.0 0.7 -0.7 -0.6 -0.7 -1.3 -1.0 0.7 0.9 0.5 0.4 -1.1 1.0 -0.4 1.0 -0.8 -0.6
Pulse wave Arterial Stiffness index 0.7 0.8 4.4 1.3 0.8 0.9 0.4 0.7 0.6 0.5 0.9 1.6 -0.3 -0.3 0.3 0.3 0.9 -0.7 0.5 1.5 1.0 -0.1 -0.1 0.4 -0.7 1.1 1.0 0.7 1.3 1.1 2.1 -0.8 -0.2 -0.5 1.3 -0.4 0.5 -0.5 0.1 1.4
Impedance of arm (left) 0.3 1.3 3.1 -1.1 -1.8 -1.1 -1.6 -0.5 -1.4 -1.3 -1.4 -1.2 0.3 1.4 -0.5 -0.7 -0.8 1.3 -1.2 -0.6 -0.5 1.3 -1.3 -1.6 1.6 -1.4 -0.9 -1.3 -1.2 -1.8 -0.4 0.7 0.2 0.9 -1.3 1.0 -1.0 1.0 -1.0 -1.3
Arm fat mass (right) 1.3 5.2 9.8 2.2 3.1 2.9 3.1 1.2 2.8 2.9 2.9 2.2 -2.1 -2.8 1.3 1.9 1.0 -2.6 2.6 2.8 1.1 -2.8 2.8 2.0 -2.7 2.7 0.3 2.4 2.6 2.2 -1.2 -2.5 -1.1 -2.1 2.5 -2.8 -0.2 -2.6 1.3 1.4
Trunk predicted mass 1.5 8.3 16.0 2.7 3.8 2.9 3.6 1.7 3.7 3.6 3.7 2.2 -2.6 -3.8 0.7 1.9 1.7 -3.1 3.4 2.4 0.9 -3.6 2.8 3.0 -4.0 3.0 1.5 3.5 3.4 3.4 -1.2 -3.0 -2.0 -2.9 3.3 -3.4 1.2 -3.3 2.7 2.0
Standing height 0.7 6.9 13.0 2.7 3.4 2.5 2.7 2.1 3.3 3.0 3.4 1.4 -3.2 -3.4 0.4 1.5 1.9 -2.7 3.1 2.5 0.9 -3.4 1.8 2.4 -3.6 2.6 1.7 3.2 3.2 3.0 -0.7 -2.9 -1.7 -2.9 3.1 -3.0 1.5 -3.0 2.8 1.9
Length of working week for main job 0.2 0.2 1.7 -0.1 0.4 -0.4 -0.2 0.4 0.2 -0.0 -0.1 -0.6 -0.3 -0.2 1.0 0.1 -0.1 0.2 0.3 -0.1 -0.4 0.4 -0.0 -0.0 0.0 0.6 0.9 0.0 -0.0 0.1 1.0 0.1 1.3 -0.5 0.1 0.2 0.6 -0.0 0.4 0.8
Exposure to tobacco smoke at home 0.4 0.5 2.7 -0.6 -0.2 0.1 0.3 -1.6 -0.3 0.1 0.1 1.3 0.6 0.1 -1.0 -1.2 -1.3 0.0 -0.4 -0.5 -0.8 0.3 0.3 0.7 0.0 -0.1 -1.0 -0.8 -0.1 -0.2 -0.3 0.0 -1.2 0.5 -0.3 -0.2 -1.3 -0.1 -1.1 -0.4
Breastfed as a baby 0.6 0.8 4.5 -0.7 -1.3 -0.8 -0.7 -0.9 -0.7 -0.8 -0.8 -0.5 0.9 0.8 -0.8 -1.1 -0.7 1.2 -1.0 -0.7 -0.7 0.6 -1.0 -0.6 0.5 -0.8 -0.0 -0.8 -0.8 -1.0 0.7 0.2 -1.1 0.8 -0.9 0.6 -2.1 0.6 -1.2 -0.6
Tense / ‘highly strung’ 0.5 0.8 2.2 1.2 1.5 0.6 1.1 0.9 1.2 1.1 1.1 -0.2 -0.7 -1.2 1.1 0.2 0.8 -0.8 1.0 0.9 0.6 -0.9 0.7 1.3 -1.2 0.9 1.0 1.2 0.9 0.9 0.1 -0.5 0.0 -1.0 1.0 -0.7 1.2 -0.7 0.6 0.2
Seen doctor (GP) for nerves, anxiety, tension or depression 0.2 0.4 2.2 0.3 -0.2 -0.6 -0.5 0.7 -0.4 -0.5 -0.6 -1.3 0.7 0.5 1.3 -0.2 -0.3 0.5 -0.3 0.0 0.4 1.0 -0.1 -0.1 0.4 0.2 0.6 0.1 -0.6 -0.5 -0.3 0.9 1.5 0.2 -0.4 0.8 0.7 0.9 -0.3 -0.0
Hair/balding pattern: Pattern 4 0.1 0.3 3.6 0.2 0.1 0.5 0.3 0.7 0.2 0.3 -0.0 -0.3 -0.6 -0.1 1.9 0.3 0.3 -0.3 0.4 0.3 0.2 -0.7 0.5 -0.5 0.1 0.3 -0.2 0.3 0.5 0.1 -0.5 -0.7 1.2 -0.5 0.4 -0.5 0.2 -0.6 -0.0 -0.6
Birth weight of first child 0.2 0.4 2.5 -0.3 -0.2 0.6 0.1 -0.7 0.0 0.4 0.2 1.3 -0.3 0.1 -0.8 -0.3 -0.7 -0.1 -0.2 0.1 -0.7 -0.7 0.5 0.2 0.1 0.3 -1.5 -0.7 0.5 -0.3 0.1 -0.9 -1.6 0.3 0.1 -0.6 -1.3 -0.6 -0.6 -0.4
Peak expiratory flow (PEF) 0.4 0.9 2.5 -1.0 -0.4 -0.8 -0.6 -1.5 -1.0 -1.0 -0.5 0.3 1.1 0.8 -1.6 -0.6 -1.3 1.0 -0.9 -0.5 -0.6 1.5 -1.0 0.1 0.6 -1.3 -1.6 -0.9 -1.3 -0.7 -0.0 1.1 -0.3 1.0 -1.0 0.8 -1.1 1.0 -0.7 -0.9
Pulse wave reflection index 0.1 0.2 1.2 0.2 0.2 -0.1 -0.3 -0.6 -0.0 -0.2 0.2 1.0 0.4 0.2 -0.3 -1.1 -0.2 0.2 -0.4 -0.2 -0.0 0.4 -0.5 0.2 -0.1 -0.5 -0.2 0.0 0.4 0.3 0.6 0.4 -0.3 0.3 0.1 0.4 0.5 0.3 -0.6 -0.3
Ever highly irritable/argumentative for 2 days 0.1 0.1 0.7 -0.0 -0.5 0.5 0.2 0.1 -0.0 0.1 0.3 0.0 -0.4 -0.1 -0.1 0.0 0.5 0.1 -0.0 -0.1 0.5 -0.5 -0.3 -0.3 -0.3 -0.2 -0.7 0.3 0.4 0.4 -0.6 -0.5 -0.7 -0.1 0.2 -0.4 0.2 -0.3 -0.2 -0.8
Loud music exposure frequency 0.2 0.2 1.2 -1.1 0.2 -0.0 -0.0 0.1 0.1 0.2 -0.0 -0.8 -0.8 -0.2 0.1 0.0 -0.7 0.1 0.1 0.1 -1.0 0.0 0.3 -0.1 0.0 0.4 -0.3 -0.6 -0.1 -0.3 -0.8 -0.2 0.7 -0.4 -0.3 -0.5 -0.7 -0.4 -0.4 -0.8
Qualifications: O levels/GCSEs or equivalent 1.1 1.7 5.3 -0.3 -1.9 -1.7 -1.6 -0.7 -1.2 -1.4 -1.3 -1.5 1.7 1.4 -0.8 -1.4 -0.8 1.9 -1.4 -2.3 0.3 1.2 -0.8 -0.3 1.6 -0.5 0.6 -0.9 -1.9 -1.4 1.1 1.4 0.3 1.6 -1.5 2.0 -0.4 1.8 -0.3 -0.0
Mouth/teeth dental problems: Bleeding gums 0.7 0.8 2.3 -0.8 -0.9 -0.9 -1.2 -1.0 -1.0 -1.0 -0.9 -1.4 1.1 1.0 0.4 -0.4 -0.1 1.1 -1.0 -0.8 0.2 0.4 -0.9 -1.3 0.9 -0.4 -0.8 -0.7 -1.4 -1.1 -0.5 0.9 0.6 0.7 -1.2 1.0 -0.2 1.1 -0.9 -1.5
Blood clot in the leg (DVT) 2.1 2.7 6.4 0.5 1.8 1.6 1.7 0.3 2.0 1.9 2.1 1.3 -2.3 -2.3 1.3 1.5 1.1 -1.9 1.9 1.5 -0.8 -2.2 1.0 -0.1 -2.4 1.2 0.7 1.5 2.0 1.3 -0.8 -2.1 -1.7 -2.1 1.8 -2.5 1.0 -2.5 1.1 0.2
Medication: Paracetamol 0.2 0.4 3.8 0.3 0.3 1.0 0.6 -0.5 0.0 0.3 0.7 2.0 -0.1 -0.2 0.5 -0.6 0.0 -0.5 0.1 0.2 0.6 -0.6 0.3 0.3 -0.4 0.1 -1.1 0.0 0.7 0.5 0.4 -0.2 -0.1 0.2 0.5 -0.5 0.2 -0.3 -1.0 -1.2
Headache pain in last month 0.2 0.3 1.8 0.5 -0.2 -0.1 -0.1 -0.0 -0.4 -0.1 -0.0 1.3 1.0 0.4 -0.2 -0.8 -0.4 0.4 -0.4 -0.3 1.0 0.3 0.2 0.4 0.4 -0.3 -0.4 -0.2 -0.2 0.1 1.2 0.6 0.9 0.6 -0.1 0.8 -0.3 0.8 -1.0 -0.4
Medication for cholesterol, blood pressure or diabetes 0.2 0.4 4.5 1.1 -0.7 0.5 0.1 0.8 -0.5 -0.1 -0.2 -0.5 0.8 0.6 -0.1 0.4 0.8 0.1 -0.2 0.6 2.1 -0.4 0.6 0.1 0.6 0.3 0.3 0.1 -0.2 0.1 1.3 -0.4 1.0 0.1 0.2 0.4 -0.1 0.3 0.0 0.7
Glaucoma (self-reported) 0.4 0.4 2.0 0.6 1.4 0.3 0.8 0.4 0.9 0.7 0.7 0.2 -0.9 -0.9 -0.1 0.4 0.1 -0.8 0.7 1.0 0.1 -0.6 0.6 0.3 -1.0 1.0 -0.2 0.9 0.4 0.7 -0.8 -0.5 -0.4 -0.4 0.6 -0.7 -0.0 -0.6 0.7 0.7
Gout (self-reported) 0.2 0.3 2.8 -0.9 -0.5 -0.1 -0.1 -0.7 -0.1 -0.1 -0.0 -0.9 -0.4 -0.1 -0.0 -0.1 -0.8 0.5 -0.1 0.0 -0.3 0.0 -0.3 -0.4 -0.0 -0.3 -0.5 -0.1 -0.1 -0.3 -1.3 -0.3 -0.2 -0.1 -0.4 -0.3 -0.8 -0.2 -0.7 -1.7
Hypothyroidism/myxoedema (self-reported) 1.5 3.0 8.9 2.6 2.3 1.7 1.6 1.8 1.6 1.4 1.3 0.3 -0.9 -1.4 1.6 1.4 1.8 -1.8 1.5 2.0 1.4 -0.9 1.8 2.4 -1.2 1.0 2.2 2.0 1.8 1.9 1.8 -0.7 0.8 -1.3 2.0 -0.9 3.0 -0.9 2.1 2.5
Medication: Amlodipine 0.5 0.7 1.7 -0.7 -0.9 -0.3 -0.6 -0.6 -1.2 -1.0 -1.1 0.3 1.3 1.1 -0.6 -1.3 -0.8 0.7 -1.2 -0.8 -0.2 0.9 -0.9 -0.1 0.9 -0.4 -0.9 -0.9 -0.1 -0.1 0.1 0.5 0.4 1.3 -0.4 0.8 -0.5 0.6 -1.1 -1.1
Medication: Ventolin 100micrograms inhaler 0.7 0.9 4.6 0.7 1.1 1.1 1.6 -0.6 0.9 1.1 1.2 2.1 -0.6 -1.0 0.1 -0.4 -0.6 -1.0 0.6 0.9 -0.2 -0.8 1.0 1.3 -1.1 0.4 -0.7 0.6 1.1 1.2 0.0 -0.9 -1.2 -0.4 0.9 -1.1 -0.2 -1.0 -0.5 -0.5
Birth weight 0.6 1.3 4.9 -1.3 -1.0 -1.4 -1.5 -1.5 -0.6 -1.0 -0.7 -1.3 0.7 0.6 -2.2 -1.7 -1.2 1.5 -1.1 -2.0 -1.4 0.5 -1.5 -1.1 0.3 -0.6 -0.5 -0.9 -0.7 -0.8 -1.0 0.9 -0.7 1.2 -1.0 0.8 -1.2 0.7 -0.4 -1.2
Chronic bronchitis/emphysema (mother) 2.3 2.7 7.2 0.3 1.4 1.9 1.4 0.5 1.9 1.9 1.9 1.0 -2.4 -1.9 0.3 1.6 1.5 -1.8 1.8 1.6 -0.6 -1.8 1.2 0.2 -1.9 1.7 0.8 1.3 2.5 1.5 -1.6 -2.4 -1.5 -1.7 2.0 -2.5 0.6 -2.7 1.8 0.7
High blood pressure (siblings) 0.3 0.4 3.7 0.8 -0.7 -0.1 0.1 0.8 -0.4 -0.3 -0.8 -0.8 0.3 0.4 1.6 0.4 0.4 0.0 -0.0 0.2 1.1 0.3 0.1 -0.2 0.7 0.8 0.5 0.1 0.0 0.2 1.6 -0.1 1.9 -0.0 0.2 0.4 0.6 0.1 -0.2 0.7
Forced vital capacity (FVC), Best measure 0.1 0.2 0.9 -0.5 -0.0 -0.6 -0.4 0.0 -0.1 -0.1 -0.0 -0.8 0.1 -0.1 -0.4 -0.4 -0.5 0.7 -0.2 -0.5 -0.4 -0.0 -0.2 0.2 0.0 0.0 -0.9 -0.3 -0.7 -0.6 0.5 0.1 0.1 -0.2 -0.6 0.2 -0.7 0.3 -0.7 -0.6
Body fat percentage 0.6 2.2 4.6 1.3 2.0 2.1 1.9 0.8 1.6 1.8 1.8 2.0 -1.6 -1.7 1.0 1.2 0.3 -1.8 1.6 2.2 0.9 -1.8 1.7 0.6 -1.6 2.0 -0.3 1.3 1.7 1.1 -1.2 -1.8 -0.7 -1.2 1.5 -2.0 -0.6 -1.7 0.3 0.4
Leg fat percentage (right) 0.2 0.7 2.3 0.5 0.8 1.3 1.1 0.1 0.6 0.9 0.9 1.5 -0.6 -0.8 0.8 0.6 -0.2 -0.9 0.7 1.1 0.7 -0.9 0.7 -0.4 -0.8 1.0 -0.4 0.4 1.0 0.4 -0.9 -1.2 -0.3 -0.6 0.8 -1.1 -1.0 -1.0 -0.7 -0.2
Arm fat-free mass (right) 1.7 8.7 17.6 2.9 4.2 3.0 3.7 1.8 3.6 3.6 3.8 3.0 -2.6 -3.8 0.7 1.9 1.7 -3.3 3.4 2.7 1.2 -3.8 2.8 2.8 -4.1 3.4 1.7 3.4 3.3 3.4 -1.1 -2.9 -1.8 -2.8 3.3 -3.4 1.0 -3.3 2.5 2.0
Exposure to tobacco smoke outside home 0.8 1.0 3.1 -1.3 -0.9 -1.0 -0.9 -1.0 -1.1 -0.9 -0.9 -1.0 0.8 0.8 -0.8 -1.2 -1.8 1.1 -1.0 -1.0 -0.4 1.0 -1.3 -0.9 0.6 -0.7 -0.7 -1.2 -0.8 -0.8 -0.9 1.0 -0.1 0.8 -1.0 0.8 -1.6 0.9 -1.5 -1.3
Comparative body size at age 10 0.3 0.8 2.8 0.8 1.1 0.7 1.2 0.9 1.2 1.2 1.2 0.1 -0.8 -1.3 0.3 0.5 0.3 -0.7 1.1 0.9 0.6 -1.1 0.7 0.6 -1.4 1.7 0.8 1.1 0.9 1.3 -0.2 -1.0 -0.7 -0.9 0.9 -0.9 -0.1 -0.9 0.4 0.6
Number of full brothers 2.0 2.5 6.5 2.0 2.0 1.4 1.5 1.9 1.6 1.6 1.7 1.3 -1.7 -1.6 1.6 1.1 0.6 -1.5 1.8 1.9 1.7 -1.5 1.0 1.3 -1.8 1.4 2.5 1.5 1.5 1.9 1.2 -1.3 1.3 -1.6 1.7 -1.3 1.2 -1.4 1.1 1.4
Worry too long after embarrassment 1.1 1.8 4.2 1.3 1.1 1.2 1.5 1.4 1.6 1.3 1.3 0.3 -1.4 -1.4 1.8 0.7 1.4 -1.1 1.4 0.5 0.5 -1.2 1.3 2.0 -1.2 1.7 1.6 1.3 1.8 1.6 1.4 -0.7 0.8 -1.3 1.8 -0.9 2.0 -1.0 1.3 1.4
Seen a psychiatrist for nerves, anxiety, tension or depression 0.4 0.6 1.8 -0.5 -0.4 -0.9 -0.5 -1.0 -0.6 -0.7 -0.8 -1.2 1.2 0.6 0.3 -0.4 -0.9 0.6 -0.6 -0.3 -0.7 1.3 -0.4 -0.3 0.5 -1.1 -0.3 -0.5 -1.1 -1.0 -0.2 1.2 0.0 0.4 -0.9 0.9 -0.1 1.0 -0.5 -0.4
Wheeze or whistling in the chest in last year 0.4 0.7 5.5 0.1 1.4 0.4 0.6 0.1 0.5 0.4 1.1 2.3 -0.9 -0.6 -1.1 -0.8 -0.8 -0.7 0.3 0.7 -0.7 -0.4 -0.6 0.3 -1.4 0.3 -0.8 -0.1 0.5 0.7 0.1 -0.1 -2.0 0.1 0.4 -0.8 -0.5 -0.6 -0.7 -0.5
Number of children fathered 1.2 1.3 3.7 1.4 0.8 1.4 1.5 0.8 1.2 1.3 1.2 0.7 -1.4 -1.2 0.0 0.6 1.5 -1.1 1.0 1.2 1.0 -1.1 1.1 1.4 -1.1 0.3 0.7 1.3 1.9 1.8 0.3 -1.3 -0.7 -1.0 1.6 -1.2 1.1 -1.3 0.6 0.5
Reason for reducing amount of alcohol drunk: Health precaution 2.1 2.5 4.5 1.7 1.5 1.5 1.7 1.6 1.8 1.9 1.4 -0.2 -1.6 -1.9 1.0 1.7 2.1 -1.6 1.9 1.4 1.5 -1.7 1.8 1.2 -1.6 1.6 0.9 2.0 1.8 1.6 -0.9 -1.6 0.6 -1.8 1.8 -1.6 0.7 -1.6 1.6 1.4
Age at first live birth 3.8 6.7 16.2 -2.1 -3.8 -2.2 -3.0 -0.6 -3.4 -3.1 -3.4 -2.8 3.1 3.6 -0.2 -1.3 -2.3 2.9 -3.0 -2.3 -0.0 3.1 -1.9 -2.3 4.0 -1.7 -0.6 -2.6 -3.2 -3.2 1.3 2.4 1.9 2.7 -3.0 3.2 -1.6 3.2 -1.9 -1.1
Pulse wave peak to peak time 0.5 0.5 4.7 -1.0 -0.8 -0.6 -0.2 -0.5 -0.3 -0.2 -0.7 -1.7 0.0 0.0 -0.0 -0.1 -0.6 0.6 -0.3 -1.3 -0.7 -0.2 0.4 -0.2 0.5 -0.9 -0.7 -0.3 -1.0 -0.9 -2.2 0.4 0.2 0.2 -1.0 0.1 -0.4 0.3 0.0 -1.3
Health satisfaction 0.2 0.3 1.3 -0.2 -0.4 -0.6 -0.5 -0.6 -0.5 -0.5 -0.4 -0.3 0.6 0.4 -0.4 -1.2 0.2 0.7 -0.6 -1.1 -0.5 0.7 -0.5 0.7 0.5 -0.8 -0.6 -0.3 -0.1 -0.6 0.7 0.6 -0.3 0.4 -0.3 0.7 0.5 0.6 -0.5 -0.2
Shortness of breath walking on level ground 1.1 1.3 3.4 0.7 1.1 1.5 1.4 0.5 0.9 1.0 1.0 1.6 -1.6 -1.2 0.8 1.1 1.2 -1.7 1.2 1.2 -0.2 -1.2 0.5 0.1 -1.4 1.2 0.7 0.9 1.8 1.1 -0.4 -1.3 -0.5 -1.2 1.6 -1.7 0.9 -1.6 0.4 0.5
Qualifications: College or University degree 0.1 0.5 2.6 -1.1 -0.9 -0.6 -0.8 -0.4 -0.7 -0.7 -0.4 -0.2 0.6 1.0 -0.9 -0.4 -0.2 -0.0 -0.6 -0.7 -0.8 0.6 -1.3 -1.6 0.6 0.2 -1.1 -1.0 -0.5 -0.5 -0.3 0.1 -0.1 0.5 -0.4 0.2 -0.3 -0.1 -0.2 -0.5
Eye problems/disorders: None of the above 0.9 1.0 2.7 -1.2 -1.0 -1.2 -0.8 -1.7 -0.9 -0.8 -0.9 0.1 1.0 0.7 -0.7 -1.1 -1.4 1.1 -0.9 -1.3 -1.0 1.0 -0.7 0.1 0.8 -1.4 -1.7 -1.2 -1.1 -1.3 0.3 1.0 -0.3 0.9 -1.2 0.9 -0.5 0.9 -0.9 -1.1
Mouth/teeth dental problems: Loose teeth 1.0 1.2 3.3 1.0 1.7 0.6 1.0 0.2 1.3 1.0 1.3 0.7 -1.7 -1.3 0.1 -0.3 1.4 -1.4 1.1 0.2 0.1 -1.7 -0.0 0.1 -1.8 0.3 0.5 1.3 1.6 1.3 -1.3 -1.0 -1.5 -0.3 1.2 -1.2 1.2 -1.3 0.9 -0.2
Emphysema/chronic bronchitis 0.8 0.9 2.3 1.0 1.4 1.2 0.7 0.3 0.9 0.8 1.2 0.2 -0.7 -1.0 0.2 1.2 1.0 -1.1 0.9 1.4 0.5 -0.9 0.8 1.0 -0.9 0.7 1.4 0.9 0.9 1.0 0.2 -0.5 -0.1 -1.1 0.9 -0.9 1.5 -0.7 1.4 1.0
Medication for pain relief, constipation, heartburn 0.1 0.2 2.9 -0.2 0.1 -0.5 -0.3 0.1 0.1 -0.1 -0.1 -1.7 0.1 0.1 -0.8 0.7 0.4 0.2 0.1 0.2 -0.5 0.2 -0.0 -0.1 0.1 -0.1 0.8 0.1 -0.5 -0.5 -0.2 -0.1 -0.5 -0.2 -0.3 0.2 0.2 0.0 1.4 1.0
Neck or shoulder pain in last month 0.3 0.4 3.0 0.5 0.9 0.6 0.5 -0.3 0.7 0.4 1.0 1.7 -0.6 -0.6 -0.6 -0.5 -0.2 -0.7 0.5 -0.0 -0.8 -0.8 0.0 0.7 -0.9 0.3 -0.1 -0.0 0.8 0.2 1.2 0.1 -0.7 0.0 0.7 -0.5 0.1 -0.5 0.4 0.6
Medication: Blood pressure 0.2 0.3 2.4 -0.7 0.5 -0.6 -0.0 -1.1 0.3 -0.0 0.1 0.8 -0.5 -0.4 0.0 -0.7 -0.8 -0.1 0.1 -0.6 -1.5 0.1 -0.9 -0.6 -0.7 -0.4 0.1 -0.0 0.2 0.1 -1.0 0.4 -0.6 0.0 -0.1 -0.2 0.1 -0.3 -0.3 -0.8
Angina (self-reported) 4.5 5.9 10.6 -3.0 -2.0 -2.7 -2.4 -2.7 -2.3 -2.5 -2.2 -1.1 2.3 1.9 -1.3 -3.0 -3.3 2.4 -2.5 -3.2 -2.6 2.2 -2.7 -2.5 1.5 -2.8 -2.6 -2.6 -2.6 -2.6 -1.4 2.7 -0.1 2.4 -3.0 2.0 -1.4 2.2 -2.6 -3.2
Migraine (self-reported) 0.1 0.2 1.3 -0.7 0.0 -0.8 -0.3 -0.8 -0.0 -0.2 -0.1 -0.5 0.1 -0.1 -0.0 -0.0 -0.1 0.1 0.1 -0.4 -0.5 0.0 -0.8 -1.1 -0.3 -0.3 0.4 -0.1 -0.4 -0.3 -1.0 0.2 0.1 -0.1 -0.3 0.0 0.1 -0.0 0.1 -0.5
Medication: Ibuprofen 0.7 0.9 4.6 1.9 0.8 0.9 0.6 1.0 0.3 0.4 0.2 1.1 -0.1 -0.2 0.7 0.4 0.5 -0.6 0.3 1.5 2.2 -0.3 1.1 1.1 0.1 0.6 1.6 1.0 0.7 1.1 1.3 -0.2 1.2 -0.3 1.0 0.0 1.3 0.0 0.5 1.3
Medication: Allopurinol 0.4 0.5 6.3 -0.9 -0.3 -0.6 -0.3 -0.6 0.2 -0.0 0.1 -1.0 -0.5 -0.4 -0.3 -0.2 -1.2 0.6 0.1 -0.3 -0.7 0.1 -0.6 -0.8 -0.5 -0.3 -0.3 0.2 -0.4 -0.5 -2.5 -0.1 -0.6 -0.1 -0.6 -0.2 -0.8 -0.1 -0.2 -1.9
Medication: Omeprazole 0.3 0.4 3.0 -0.7 -0.4 -0.5 -0.3 -0.5 -0.0 -0.1 -0.1 0.1 -0.2 0.1 0.3 -0.8 -0.4 0.6 -0.3 -1.0 -0.7 -0.1 -0.1 -0.6 0.1 -0.6 -1.7 -0.2 -0.6 -0.6 -1.2 0.0 -0.1 0.1 -0.8 0.1 -0.4 0.1 -0.8 -1.7
Medication: Seretide 50 evohaler 1.1 1.3 3.1 0.7 1.0 1.2 1.4 1.7 1.3 1.5 1.8 1.7 -1.4 -1.3 0.3 0.0 -0.2 -0.8 1.2 1.4 0.3 -1.2 0.9 0.5 -1.6 1.5 0.3 0.7 1.2 1.1 0.7 -1.6 -1.2 -1.0 1.0 -1.4 -1.1 -1.3 -0.7 -0.5
Mean time to correctly identify matches 0.5 0.9 3.3 0.2 0.4 -0.5 -0.6 -1.1 -0.7 -0.9 -1.0 -1.8 1.2 0.9 0.0 -0.6 -0.4 0.4 -0.9 -0.7 0.1 1.0 0.4 1.3 1.6 -1.6 -0.3 -0.3 -0.9 -0.5 0.0 1.8 0.7 0.8 -0.8 1.4 1.7 1.5 0.8 0.5
Heart disease (mother) 1.4 1.6 3.9 -0.4 -2.0 -1.1 -1.3 -0.3 -1.2 -1.3 -1.1 -0.0 1.8 1.4 -0.6 -1.5 -1.5 1.9 -1.5 -1.6 0.3 1.3 -0.7 -0.2 1.6 -1.0 -1.3 -1.1 -1.5 -1.2 1.7 1.3 0.4 1.6 -1.3 1.8 -1.0 1.8 -1.5 -0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.7 0.8 2.4 0.5 0.3 0.7 0.4 0.7 0.8 0.6 0.6 0.5 -1.2 -0.6 0.8 1.5 1.0 -1.0 0.9 1.0 -0.3 -0.5 0.4 0.1 -0.6 0.7 1.3 0.7 1.0 0.8 0.8 -1.1 -0.3 -1.0 0.9 -1.1 1.5 -1.2 1.5 1.1
Whole body fat mass 1.4 5.7 10.3 2.2 3.2 3.0 3.0 1.5 2.8 3.0 3.0 2.6 -2.4 -2.9 1.4 1.9 1.0 -2.8 2.7 3.0 1.2 -3.0 2.7 1.7 -2.9 3.1 0.5 2.4 2.7 2.2 -1.4 -2.7 -1.1 -2.2 2.5 -3.0 -0.2 -2.8 1.2 1.1
Leg fat mass (right) 1.0 3.8 6.9 1.9 2.4 2.5 2.6 1.1 2.2 2.4 2.4 2.3 -1.8 -2.3 1.2 1.6 0.9 -2.3 2.2 2.3 1.3 -2.5 2.2 1.3 -2.3 2.5 0.4 1.9 2.3 1.9 -1.0 -2.3 -0.8 -1.7 2.1 -2.4 -0.5 -2.2 0.8 1.2
Arm predicted mass (right) 1.4 7.2 15.0 2.5 3.9 2.8 3.3 1.4 3.3 3.2 3.6 3.1 -2.2 -3.5 0.2 1.5 1.4 -3.1 3.0 2.5 0.9 -3.5 2.4 2.5 -3.9 3.1 1.4 3.0 3.1 3.2 -1.1 -2.7 -2.1 -2.4 3.0 -3.2 0.7 -3.1 2.1 1.7
Pulse rate, automated reading 0.3 0.8 2.2 -1.1 0.2 -1.0 -0.6 -0.3 -0.8 -0.8 -0.7 -0.3 0.9 0.8 -0.5 -1.2 -0.8 0.6 -0.9 -1.5 -1.2 1.0 -0.4 -0.3 1.0 -0.7 -1.5 -1.3 -1.3 -1.2 0.3 1.5 -0.0 1.1 -1.1 1.0 -0.5 1.1 -0.8 -0.3
Alcohol intake frequency. 1.0 2.4 6.1 -1.3 0.4 -1.6 -1.2 -1.7 -0.9 -1.4 -0.6 1.9 1.3 0.9 -1.7 -2.3 -2.5 1.2 -1.4 -1.5 -2.4 1.6 -1.5 -0.0 0.6 -1.7 -2.0 -1.9 -1.7 -1.9 1.2 2.4 -1.4 1.6 -1.7 1.4 -0.8 1.7 -1.2 -0.5
Comparative height size at age 10 0.3 1.5 3.5 1.3 1.8 0.9 1.1 0.7 1.7 1.3 1.6 0.6 -1.6 -1.7 -0.9 -0.1 -0.4 -1.0 1.3 0.9 -0.1 -1.6 0.5 1.3 -1.9 1.1 0.8 1.4 1.4 1.1 -0.6 -1.3 -1.8 -1.1 1.4 -1.4 -0.3 -1.5 1.5 1.3
Number of full sisters 0.6 0.8 4.4 0.3 0.7 0.6 1.0 -0.3 0.9 0.8 0.8 2.1 -0.6 -1.1 0.2 0.7 1.2 -1.1 1.0 0.7 -0.6 -0.9 -0.1 -0.5 -1.6 0.1 -0.3 0.6 1.0 0.4 -0.9 -1.1 -1.3 -1.0 0.9 -1.3 -0.0 -1.3 0.4 0.1
Suffer from ‘nerves’ 0.1 0.1 0.8 0.1 -0.3 0.0 0.1 0.1 0.1 0.1 0.1 -0.8 0.0 0.0 0.9 0.4 0.1 0.2 0.1 0.5 -0.0 0.1 0.1 -0.6 0.0 0.4 0.1 0.3 -0.2 -0.4 -0.3 -0.1 -0.5 -0.5 -0.1 0.1 0.0 0.1 -0.1 -0.2
Overall health rating 0.7 1.6 5.1 0.5 2.3 0.8 1.3 0.0 1.9 1.6 1.9 1.3 -1.4 -2.2 0.2 -0.3 0.2 -1.0 1.4 -0.3 -1.2 -1.6 1.3 1.5 -2.2 1.2 0.1 1.1 1.1 0.9 -1.3 -0.4 -1.2 -1.6 0.9 -1.3 0.8 -1.1 0.8 0.1
Chest pain or discomfort 1.1 1.6 4.3 -1.3 -0.3 -1.5 -1.4 -2.1 -1.1 -1.2 -0.8 0.1 1.0 0.6 -1.1 -1.8 -2.0 1.4 -1.3 -1.2 -1.0 1.1 -1.3 -0.9 0.4 -1.2 -1.6 -1.2 -1.5 -1.3 -0.6 1.6 -0.4 1.0 -1.7 1.1 -0.4 1.3 -1.7 -1.9
Had major operations 0.5 0.6 3.3 0.4 0.1 0.8 0.6 1.0 0.3 0.6 0.3 -0.2 -0.7 -0.4 0.6 1.8 1.1 -0.9 0.9 0.8 0.9 -0.4 0.8 0.7 -0.2 0.8 1.3 0.7 0.5 0.6 -1.0 -0.5 1.0 -0.5 0.7 -0.7 0.2 -0.7 1.4 1.1
Age at last live birth 5.0 7.2 13.5 -2.9 -3.7 -2.6 -3.0 -1.5 -3.1 -3.0 -3.1 -2.2 2.8 3.1 -0.6 -1.8 -3.0 3.4 -3.0 -3.0 -1.2 3.0 -1.9 -2.4 3.6 -2.4 -1.8 -2.8 -3.6 -3.4 -0.1 2.5 0.7 2.6 -3.5 3.0 -2.2 3.1 -2.4 -2.3
Family relationship satisfaction 0.4 0.5 2.1 -0.6 -0.8 -0.8 -0.7 -0.7 -0.6 -0.8 -0.9 -1.5 0.3 0.6 0.0 -0.1 0.1 0.9 -0.5 -1.2 -0.4 0.5 -0.8 -0.4 0.5 -1.2 -0.2 -0.6 -0.7 -0.7 0.6 0.8 0.5 0.5 -0.7 0.8 0.0 0.8 -0.3 0.0
Leg pain on walking 0.4 0.4 1.6 -0.0 0.9 -0.1 0.0 -0.1 1.0 0.6 0.9 0.4 -0.8 -1.0 -1.2 -0.8 -0.1 -0.2 0.6 -0.8 -1.1 -0.8 0.0 0.3 -1.1 0.4 -0.1 0.4 0.4 0.2 -1.3 -0.2 -1.2 -0.4 0.1 -0.5 0.4 -0.6 0.9 -0.2
Qualifications: NVQ or HND or HNC or equivalent 0.4 0.4 3.0 -0.9 -0.6 -0.4 -0.5 -0.3 -0.0 -0.1 -0.2 0.7 -0.0 0.0 0.0 0.2 -1.0 0.6 -0.1 -0.3 -1.0 0.2 -0.2 -1.3 -0.1 0.0 -0.6 -0.3 -0.7 -1.0 -1.7 -0.3 -0.7 -0.1 -0.8 -0.2 -1.4 -0.1 -0.7 -1.2
Commuting to job workplace: Car/motor vehicle 0.4 0.4 1.4 0.2 0.4 0.3 0.3 0.1 0.7 0.7 0.8 0.5 -1.2 -0.8 0.3 0.4 -0.8 -0.1 0.6 0.8 0.3 -1.1 0.1 -0.4 -1.0 0.6 -0.5 0.8 0.3 0.4 -0.8 -1.0 -1.1 -0.9 0.3 -0.9 -0.2 -0.7 -0.1 -0.8
Illness, injury, bereavement, stress in last 2 years 0.3 0.3 1.0 0.4 0.5 1.0 0.7 -0.5 -0.0 0.3 0.3 1.0 0.1 -0.0 -0.6 0.6 0.9 -1.0 0.2 0.9 0.2 -0.3 0.2 0.4 -0.2 -0.2 -0.6 0.3 0.8 0.7 -0.4 -0.4 -1.0 -0.2 0.7 -0.6 0.4 -0.6 0.3 0.5
Medication: Aspirin 0.7 0.9 3.3 -1.1 0.3 -1.3 -0.8 -1.0 -0.5 -1.0 -0.8 -0.3 0.3 0.2 -0.0 -1.6 -1.3 0.4 -0.6 -1.7 -1.8 1.0 -1.4 -0.4 0.1 -1.2 -1.1 -0.9 -0.7 -0.3 -0.6 1.7 0.0 0.8 -0.9 0.8 0.4 0.9 -1.0 -0.8
Supplements: Vitamin C 1.1 1.3 2.8 -0.7 -1.1 -1.2 -1.2 -0.5 -1.1 -1.3 -1.2 -1.1 1.5 1.1 -1.0 -1.6 -1.3 1.5 -1.3 -1.6 -0.3 1.4 -1.1 -0.8 1.2 -1.1 -0.4 -1.0 -1.3 -1.0 0.7 1.5 0.3 1.5 -1.2 1.6 -1.1 1.7 -0.7 -0.1
Knee pain experienced in last month 0.4 0.6 3.2 -0.9 0.2 -0.9 -0.4 -0.6 0.4 -0.2 -0.1 -0.2 -0.6 -0.4 -0.9 -1.3 -0.8 0.6 -0.2 -1.6 -1.5 -0.0 -0.4 -0.6 -0.3 -0.6 -1.4 -0.2 -0.3 -0.4 -1.8 0.7 -1.6 0.4 -0.6 0.2 -0.3 0.3 -0.0 -0.7
Hypertension (Self-reported) 0.4 1.1 3.1 0.5 1.4 0.7 1.2 0.3 1.5 1.2 1.2 0.5 -1.3 -1.5 1.2 0.8 0.6 -1.1 1.3 0.5 -0.4 -1.2 0.5 -0.0 -1.8 1.4 0.7 1.0 1.4 1.2 -0.4 -0.9 -0.4 -1.2 1.2 -1.3 0.3 -1.4 0.6 0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.5 0.6 4.3 -0.8 0.1 0.4 0.1 -0.1 0.2 0.4 0.8 2.1 -0.6 -0.2 -0.9 -0.0 -0.7 -0.3 0.1 0.3 -1.0 -0.4 -0.2 -1.1 -0.7 0.0 -1.2 -0.3 0.2 -0.2 -1.1 -0.6 -1.8 -0.0 -0.1 -0.9 -0.9 -0.6 -0.6 -1.3
Illnesses of father: Heart disease 2.5 3.5 10.0 -2.2 -1.1 -2.1 -2.0 -3.2 -1.6 -1.7 -1.4 -0.4 2.2 1.4 -1.9 -2.3 -2.6 2.0 -2.0 -1.9 -2.4 1.9 -1.9 -1.6 1.1 -1.6 -2.1 -2.0 -1.9 -1.9 -0.6 2.0 -1.0 1.9 -2.1 1.5 -1.1 1.6 -1.5 -2.1
Illnesses of siblings: Diabetes 0.6 0.7 2.6 0.0 0.8 0.4 0.8 -0.5 1.1 1.1 0.9 1.1 -1.1 -1.2 0.6 0.3 -0.3 -0.7 0.9 0.3 -0.6 -1.2 0.6 -0.0 -1.3 0.5 0.5 0.7 0.7 0.3 -1.6 -1.0 -0.8 -1.1 0.5 -1.3 -0.9 -1.2 -0.3 -0.5
Smoking status: Previous 0.3 0.5 3.4 0.2 0.5 1.0 0.6 -0.5 0.2 0.3 0.6 1.7 -0.6 -0.1 -1.0 -0.1 0.2 -0.8 0.1 0.9 -0.5 -0.4 0.3 1.3 -0.2 0.0 -0.4 -0.3 0.9 0.2 1.2 -0.7 -1.9 0.2 0.7 -0.7 -0.1 -0.7 -0.0 0.6
Forced expiratory volume in 1-second (FEV1), predicted 0.1 0.2 1.3 0.2 0.1 -0.4 0.0 0.9 0.2 0.3 0.2 -0.1 -0.2 -0.6 -0.0 -0.6 -1.0 0.5 0.3 -0.3 0.4 -0.5 -0.4 -0.5 -0.8 0.6 0.5 0.6 -0.1 -0.1 -0.9 -0.5 -0.0 -0.1 -0.1 -0.2 -0.9 -0.2 -0.5 -1.1
Whole body fat-free mass 1.7 9.7 17.7 3.0 4.2 3.3 3.9 2.1 3.9 3.8 4.0 2.6 -2.8 -4.0 0.8 2.2 1.9 -3.4 3.6 3.0 1.2 -3.8 3.1 3.3 -4.2 3.4 1.7 3.6 3.6 3.6 -1.0 -3.2 -2.0 -3.0 3.5 -3.6 1.1 -3.4 2.8 2.4
Leg fat-free mass (right) 1.9 10.3 20.1 3.3 4.5 3.5 4.1 2.3 3.9 3.9 4.0 2.7 -3.0 -4.0 1.2 2.4 1.9 -3.6 3.7 3.5 1.5 -3.8 3.6 3.8 -3.9 3.7 1.6 3.7 3.5 3.6 -0.7 -3.1 -1.7 -3.0 3.5 -3.5 1.2 -3.3 2.9 2.8
Arm fat percentage (left) 0.7 2.7 5.7 1.4 2.4 2.3 2.3 0.6 1.9 2.1 2.1 2.2 -1.5 -1.9 1.0 1.3 0.2 -2.0 1.8 2.3 0.7 -1.9 2.3 1.3 -1.8 2.0 -0.5 1.4 1.8 1.3 -1.2 -1.8 -0.9 -1.3 1.6 -2.1 -0.8 -1.8 0.4 0.6
Average weekly red wine intake 2.1 3.1 6.7 1.5 1.8 1.2 1.7 2.0 2.3 2.1 2.1 1.0 -2.1 -2.3 -0.4 1.0 1.6 -1.4 2.1 1.1 0.9 -1.8 1.2 1.4 -2.3 2.2 1.7 2.2 2.1 2.6 -0.7 -2.0 -0.9 -1.9 2.1 -1.8 0.8 -2.0 2.2 1.9
Handedness (chirality/laterality): Left-handed 0.2 0.3 1.2 -0.3 0.3 0.2 0.5 -0.3 0.7 0.5 0.5 0.5 -0.8 -0.6 1.0 0.3 0.1 -0.6 0.6 0.0 -1.1 -0.1 0.1 0.3 -0.8 0.3 -0.1 0.1 0.4 0.4 0.3 -0.6 -0.4 -0.7 0.4 -0.8 0.8 -0.9 0.3 -0.1
Mood swings 1.4 2.5 5.9 -1.9 -0.8 -1.7 -1.5 -2.3 -1.2 -1.3 -1.0 0.1 0.8 1.0 -1.8 -2.2 -2.4 1.6 -1.5 -1.3 -2.1 1.3 -1.8 -1.0 0.6 -1.7 -2.1 -1.5 -1.6 -2.0 -1.6 1.5 -1.6 1.5 -1.9 1.0 -1.8 1.2 -1.6 -2.1
Loneliness, isolation 0.5 0.6 2.1 -0.5 0.1 -1.1 -0.6 -0.8 -0.3 -0.6 -0.7 -0.7 0.4 0.3 1.5 -0.9 -1.3 0.9 -0.5 -0.5 -0.8 0.8 -0.5 0.2 0.4 -1.3 0.0 -0.5 -1.1 -1.1 0.2 1.1 0.8 0.2 -1.1 0.8 -0.5 0.8 -1.3 -1.1
Long-standing illness, disability or infirmity 1.1 1.7 6.3 -2.1 -0.1 -1.3 -1.2 -1.0 -0.7 -0.8 -0.4 0.7 0.4 0.5 -1.0 -1.3 -2.4 1.1 -0.9 -1.3 -2.3 1.2 -1.1 -1.5 0.3 -0.5 -2.5 -1.6 -1.4 -1.6 -1.1 1.2 -1.1 0.5 -1.6 0.5 -1.4 0.7 -1.5 -1.8
Ever had bowel cancer screening 0.7 0.8 2.5 -0.2 -1.2 -0.9 -1.0 -0.7 -1.1 -1.2 -1.6 -1.6 1.0 1.2 -0.1 -0.5 0.1 1.0 -1.2 -0.7 0.2 1.2 -0.8 -0.1 1.5 -1.3 0.1 -0.3 -0.7 -0.6 0.5 0.8 0.7 1.0 -0.7 1.2 0.3 1.1 -0.1 0.2
Diabetes diagnosed by doctor 0.2 0.4 3.1 -0.9 0.4 -0.1 -0.2 -0.6 -0.1 -0.3 0.1 0.5 0.2 0.2 -1.2 -0.5 -1.4 -0.1 -0.2 -0.5 -1.8 0.5 -0.4 0.0 -0.0 -0.2 -0.2 -1.0 -0.2 -0.5 -0.5 0.6 -1.1 0.6 -0.2 0.0 -0.7 0.0 0.4 0.2
Ever had stillbirth, spontaneous miscarriage or termination 1.1 1.2 6.7 -1.5 -1.4 -1.3 -1.0 -1.3 -0.0 -0.3 -0.0 0.2 -0.1 -0.1 -0.9 -1.6 -1.5 1.4 -0.4 -2.6 -1.6 0.4 -1.1 -1.6 -0.2 -0.7 -0.7 -0.8 -0.6 -0.6 -1.4 0.5 -0.9 0.5 -1.0 0.4 -1.6 0.4 -0.7 -1.7
Friendships satisfaction 0.3 0.3 2.0 -1.1 -0.5 -0.9 -0.7 -0.9 0.0 -0.2 -0.4 -1.1 -0.1 -0.2 -0.0 0.0 -0.1 0.7 -0.0 -0.9 -1.4 0.3 -0.8 -0.9 -0.3 -0.4 -0.3 -0.2 -0.2 -0.5 -1.1 0.1 -0.4 -0.2 -0.5 -0.0 0.0 -0.1 -0.0 -0.6
Qualifications: nursing, teaching 0.3 0.5 3.0 0.2 -0.7 -0.1 -0.7 1.1 -0.5 -0.6 -0.3 -0.3 0.6 0.7 0.0 0.4 0.3 0.2 -0.3 -0.5 0.9 0.6 -0.1 0.3 0.8 0.4 1.0 -0.4 -0.5 -0.2 1.6 0.5 1.7 0.3 -0.1 0.7 0.0 0.6 0.6 1.3
Commuting to job workplace: Walk 1.0 1.0 8.0 0.1 -0.1 -0.5 -0.5 0.5 -0.8 -0.9 -1.0 -1.7 1.4 0.9 0.8 -0.3 0.1 0.4 -0.6 -0.6 0.5 1.3 0.1 1.0 1.2 -0.4 1.5 -0.6 -1.0 -0.5 2.0 1.5 2.8 0.6 -0.6 1.3 0.6 1.2 -0.5 0.8
Eye problems/disorders: Cataract 0.9 1.1 3.7 1.3 0.6 1.2 0.8 1.9 0.9 0.7 0.9 0.5 -1.2 -0.6 0.9 1.0 1.8 -1.0 0.9 1.0 1.2 -1.1 0.4 0.4 -0.8 1.4 1.3 1.1 1.3 1.3 0.6 -0.9 0.5 -0.9 1.3 -0.7 1.0 -0.8 1.2 1.3
Mouth/teeth dental problems: Mouth ulcers 1.3 2.1 4.0 -0.9 -0.6 -1.7 -1.5 -0.7 -1.7 -1.9 -1.6 -1.6 1.8 2.0 -0.5 -1.4 -0.8 1.4 -1.7 -1.0 -0.4 2.0 -1.7 -1.1 1.7 -1.7 -1.1 -1.5 -1.8 -1.6 1.0 2.0 0.3 1.8 -1.5 2.0 0.5 1.9 -0.9 -0.8
Medication for cholesterol 0.4 0.7 2.7 -0.0 -1.6 -0.6 -1.1 0.2 -1.3 -1.1 -1.1 -0.5 0.6 1.2 -0.2 -0.1 -0.4 0.9 -0.9 -0.1 0.6 1.0 -1.4 -1.2 1.0 -0.6 0.7 -0.6 -0.7 -1.0 0.3 0.5 0.6 0.9 -0.6 0.9 -0.3 0.9 -0.6 -0.2
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.3 0.3 1.5 0.7 -0.8 0.2 0.0 1.0 0.4 0.5 0.1 -1.0 0.4 -0.2 0.8 1.2 0.9 0.4 0.4 0.5 1.1 -0.3 0.9 -0.3 -0.0 0.4 0.8 0.9 -0.1 -0.0 0.3 -0.3 -0.3 -0.5 0.1 0.1 -0.3 0.2 0.4 0.7
Back pain experienced in last month 0.1 0.2 1.4 -0.1 -0.1 -0.1 -0.0 0.3 0.5 0.4 0.5 -0.4 -0.3 -0.7 -0.5 -0.3 -0.4 0.4 0.3 -0.6 -0.2 -0.3 0.1 -0.4 -0.7 0.1 0.1 0.4 0.3 0.1 -1.2 -0.1 -0.5 -0.4 0.1 -0.2 0.3 -0.2 0.5 -0.4
Mineral and other dietary supplements 1.3 1.8 5.3 0.5 1.9 1.1 1.5 1.2 1.6 1.6 1.9 2.3 -1.7 -1.8 -0.3 0.5 0.6 -1.6 1.5 1.2 -0.3 -1.3 1.0 0.8 -2.0 1.4 -0.1 1.1 1.2 1.2 -1.4 -1.2 -1.8 -1.4 1.2 -1.7 0.8 -1.6 1.2 0.3
Breast cancer (self-reported) 0.5 0.6 3.3 0.4 0.0 0.9 0.4 0.7 0.5 0.8 0.7 0.7 -0.9 -0.4 0.5 0.7 0.4 -0.6 0.8 1.1 0.8 -0.9 0.2 -0.7 -0.6 0.8 0.9 0.5 1.2 0.6 -0.4 -1.8 0.1 -1.2 0.9 -1.1 -0.0 -1.4 0.2 0.1
Asthma (self-reported) 0.5 0.9 5.3 1.4 0.7 1.1 1.3 0.3 0.9 0.8 1.2 2.3 -0.9 -0.8 -0.1 -0.1 0.6 -0.8 0.6 0.7 1.0 -0.9 0.7 1.7 -1.0 0.3 0.5 0.9 1.1 1.6 1.3 -0.6 -1.2 -0.2 1.1 -0.7 0.6 -0.6 0.4 0.7
Osteoporosis (self-reported) 0.1 0.2 1.1 -0.3 0.6 -0.1 -0.0 0.2 0.4 0.3 0.6 0.4 -0.1 -0.4 -0.4 -0.1 -0.7 0.2 0.2 0.3 -0.1 0.1 0.0 0.1 -0.5 -0.2 -0.6 0.2 -0.2 0.0 -0.9 -0.2 -1.1 -0.5 -0.2 -0.2 -0.4 -0.2 0.1 -0.5
Osteoarthritis (self-reported) 1.2 1.6 3.7 0.1 1.3 1.4 1.4 0.9 1.7 1.6 1.9 0.9 -1.7 -1.9 1.1 0.8 0.9 -1.4 1.6 0.3 -1.1 -1.9 1.2 0.6 -1.9 0.9 0.3 0.7 1.6 1.2 -0.5 -1.1 -0.4 -1.7 1.3 -1.8 0.6 -1.7 0.6 0.0
Medication: Aspirin 0.8 1.0 4.6 -1.3 0.1 -1.5 -0.9 -0.9 -0.4 -1.0 -0.9 -0.6 0.3 0.2 0.1 -1.7 -1.3 0.6 -0.7 -1.9 -2.1 1.1 -1.4 -0.4 0.2 -1.1 -1.3 -0.9 -0.8 -0.5 -0.7 1.7 -0.1 0.8 -1.0 0.8 0.2 0.9 -1.0 -0.8
Medication: Gliclazide 0.6 0.7 2.7 -1.1 -0.5 -0.7 -0.6 -0.5 -0.6 -0.7 -0.6 0.3 0.8 0.7 -0.8 -1.3 -1.7 0.5 -0.7 -1.1 -1.3 0.8 -0.8 -0.7 0.5 0.3 -1.4 -1.2 -0.6 -0.8 -0.3 0.8 -0.1 1.0 -0.7 0.5 -1.3 0.4 -0.6 -0.6
Illnesses of father: None of the above (group 1) 0.6 0.7 2.2 0.5 0.4 0.8 0.9 0.9 1.1 1.0 0.9 1.2 -1.5 -1.0 -0.1 0.0 0.2 -0.8 0.8 0.1 -0.2 -1.4 0.7 0.2 -1.0 0.7 -0.3 0.8 1.2 0.6 -0.9 -1.2 -1.2 -0.8 0.9 -1.1 -0.2 -1.2 0.5 0.5
Smoking status: Current 0.3 0.4 1.7 -0.7 0.1 -1.2 -0.8 -0.2 -0.2 -0.4 -0.6 -1.1 0.3 -0.1 0.7 -0.5 -0.7 0.4 -0.1 -0.6 -0.7 0.5 -0.7 -1.3 -0.2 -0.4 0.0 -0.2 -0.9 -0.6 -1.2 0.6 0.9 0.0 -0.8 0.3 -0.3 0.4 -0.6 -0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.2 2.4 4.7 -1.8 -1.9 -2.1 -1.8 -1.5 -1.5 -1.5 -1.7 -0.8 1.5 1.3 -0.9 -1.2 -1.4 2.0 -1.5 -2.0 -1.6 0.9 -1.7 -1.9 1.1 -1.5 -1.6 -1.6 -2.0 -2.2 -0.5 0.8 -0.5 1.1 -2.0 1.1 -2.0 1.0 -1.8 -2.0
Whole body water mass 1.6 9.3 16.9 3.0 4.1 3.2 3.9 2.0 3.8 3.7 3.9 2.6 -2.7 -3.9 0.9 2.1 1.9 -3.4 3.5 2.9 1.2 -3.8 3.1 3.2 -4.1 3.4 1.7 3.5 3.6 3.6 -1.0 -3.1 -1.9 -3.0 3.5 -3.5 1.1 -3.4 2.6 2.3
Leg predicted mass (right) 2.0 10.5 20.5 3.3 4.5 3.6 4.2 2.4 3.9 3.9 4.0 2.7 -2.9 -4.0 1.2 2.4 2.0 -3.6 3.7 3.6 1.5 -3.8 3.7 3.9 -3.9 3.7 1.6 3.7 3.5 3.6 -0.6 -3.1 -1.6 -3.0 3.6 -3.5 1.3 -3.3 2.9 2.8
Arm fat mass (left) 1.4 5.7 11.2 2.2 3.4 2.9 3.2 1.3 2.9 3.1 3.0 2.3 -2.2 -2.9 1.1 1.9 0.9 -2.8 2.7 2.9 0.9 -3.0 2.9 2.1 -2.9 2.7 0.3 2.4 2.7 2.2 -1.3 -2.7 -1.5 -2.2 2.5 -3.0 -0.3 -2.7 1.4 1.4
Number of self-reported non-cancer illnesses 0.3 0.6 2.6 -0.5 1.6 0.2 0.5 -0.4 1.1 0.7 0.9 0.4 -1.0 -1.1 1.1 0.5 -0.2 -0.7 0.9 0.4 -1.6 -0.5 0.4 -0.1 -1.3 0.3 -0.8 0.3 0.4 0.1 -1.1 0.0 -0.8 -0.7 0.2 -0.9 0.4 -0.6 0.2 -0.5
Average weekly champagne plus white wine intake 0.5 0.7 4.2 1.0 0.4 0.5 0.5 1.6 0.3 0.4 0.2 -1.1 -0.4 -0.1 0.7 0.7 0.8 -0.6 0.4 0.4 1.1 0.2 0.7 1.2 0.3 -0.1 0.8 0.5 0.8 0.9 2.0 -0.1 1.1 -0.4 1.0 0.1 2.0 -0.1 1.0 1.4
Miserableness 2.3 4.0 10.1 -1.8 -1.4 -2.3 -1.9 -2.0 -1.8 -2.0 -1.4 0.3 2.2 1.8 -2.0 -3.2 -2.6 2.3 -2.2 -2.4 -1.9 2.1 -2.3 -0.3 1.3 -2.1 -2.1 -2.1 -2.1 -2.1 0.6 2.6 -1.0 2.3 -2.3 2.2 -1.4 2.3 -2.2 -2.0
Guilty feelings 0.8 1.2 3.7 -0.4 -0.2 -1.3 -1.0 -0.9 -0.9 -1.2 -1.0 -1.4 1.1 1.0 0.3 -1.5 -1.1 1.0 -1.0 -0.9 -0.8 1.5 -0.9 0.9 1.1 -1.3 0.1 -1.0 -1.1 -0.9 1.9 1.9 0.9 1.0 -0.9 1.6 1.2 1.5 -0.3 -0.1
Wears glasses or contact lenses 0.3 0.3 1.8 -0.4 0.0 0.0 -0.1 -0.6 -0.3 -0.5 -0.3 0.2 0.3 0.4 -1.0 -0.7 0.1 -0.2 -0.6 -0.4 -1.0 0.7 -0.6 0.3 0.2 -0.8 -1.3 -0.7 0.4 0.2 0.9 0.7 -0.8 0.8 0.2 0.2 0.7 0.2 -0.1 -0.0
Ever taken oral contraceptive pill 1.0 1.1 2.8 -0.8 -0.7 -1.4 -1.3 -0.6 -1.1 -1.2 -1.3 0.4 1.1 1.1 -1.7 -1.4 -0.9 1.4 -1.3 -0.6 -0.5 1.5 -1.1 -0.5 1.1 -1.5 -0.6 -0.8 -0.9 -1.1 0.0 1.0 -0.5 1.4 -1.0 1.4 -0.7 1.3 -0.9 -0.8
Hearing aid user 0.3 0.4 2.6 0.5 -0.3 -0.3 -0.5 -0.5 -0.5 -0.6 -0.2 0.3 1.0 0.7 -0.8 -0.3 0.4 0.5 -0.6 -0.3 0.7 0.5 -0.3 0.3 0.6 -0.7 -0.2 -0.1 -0.5 -0.2 1.6 1.0 0.1 0.8 -0.3 1.1 0.3 1.1 -0.0 0.7
Mother’s age at death 0.4 0.5 2.4 0.5 0.2 0.8 0.5 0.5 0.4 0.4 0.1 0.5 -0.5 -0.3 -0.5 1.2 0.7 -0.7 0.5 1.3 0.2 -0.5 0.5 0.0 -0.2 0.6 0.5 0.6 0.7 0.5 -0.5 -1.1 -0.8 -0.5 0.8 -0.8 -0.6 -0.8 1.1 1.6
Financial situation satisfaction 0.4 0.5 2.6 -1.3 -0.2 0.1 -0.2 -1.5 -0.0 0.1 0.1 -0.6 -0.4 -0.2 0.2 0.2 -0.3 0.3 0.0 -0.3 -1.3 -0.3 -0.3 -0.9 -0.4 -0.4 -1.4 -0.5 0.1 -0.5 -1.0 -0.6 -1.4 -0.4 -0.4 -0.6 -1.2 -0.6 -1.1 -1.6
Tinnitus: Yes, now most or all of the time 0.1 0.1 0.3 -0.2 0.5 -0.2 -0.2 0.1 0.1 0.1 0.0 -0.3 0.4 -0.2 0.1 0.3 -0.3 0.2 0.0 0.4 -0.3 -0.1 0.1 0.4 -0.2 -0.6 0.2 0.0 -0.4 -0.3 -0.4 0.0 -0.5 -0.2 -0.4 -0.0 -0.4 0.1 -0.4 -0.4
Commuting to job workplace: Public transport 1.0 1.2 3.1 -1.5 -1.0 -0.9 -1.2 -1.0 -1.2 -1.3 -0.8 0.6 1.0 1.3 -1.7 -1.4 -0.8 0.8 -1.1 -0.9 -1.2 1.3 -1.8 -1.2 0.9 -0.6 -1.4 -1.6 -0.9 -1.1 0.1 1.0 -0.9 1.4 -0.9 0.9 -1.1 0.8 -0.5 -0.3
Eye problems/disorders: Glaucoma 2.0 2.4 4.3 1.5 1.7 1.2 1.5 1.2 2.1 1.8 1.6 0.3 -2.0 -2.0 0.3 1.4 1.1 -1.6 1.8 1.3 0.5 -1.7 1.4 0.6 -2.1 1.9 1.1 2.0 1.7 1.6 -1.7 -1.8 -0.8 -1.6 1.7 -1.8 0.7 -1.9 2.0 1.4
Medication: Blood pressure 0.2 0.3 1.1 -0.1 0.8 0.6 0.6 0.1 0.6 0.6 0.5 -0.5 -0.5 -0.7 0.4 0.5 0.8 -0.7 0.6 0.3 -0.2 -0.8 0.5 -0.2 -0.8 1.0 -0.2 0.4 0.9 0.9 -0.5 -0.6 -0.1 -0.8 0.7 -0.8 -0.0 -0.8 0.1 -0.0
Pain type(s) experienced in last month: Hip pain 0.2 0.3 2.9 0.4 0.7 0.7 0.6 0.6 0.4 0.3 0.5 -0.2 -0.4 -0.4 -0.7 0.4 0.2 -0.8 0.4 1.0 -0.2 -0.6 0.3 0.1 -0.5 0.4 -0.0 0.5 0.4 -0.1 -0.6 -0.2 -1.7 0.2 0.3 -0.5 -0.0 -0.3 0.8 0.3
Supplements: Fish oil (including cod liver oil) 0.5 0.6 2.6 -0.3 -1.6 -0.6 -0.8 -1.0 -1.1 -0.8 -1.2 -1.0 1.0 1.1 -0.1 0.3 -0.5 0.8 -0.8 -0.5 0.4 0.5 -0.5 -1.1 1.3 -0.9 0.1 -0.6 -0.7 -0.9 -0.3 0.2 1.0 0.7 -0.7 0.7 -0.8 0.5 -0.5 -0.2
High cholesterol (Self-reported) 0.3 0.6 1.7 -1.1 -0.4 -1.1 -0.9 -0.5 -0.4 -0.7 -0.8 -0.9 0.4 0.4 -0.2 -0.6 -1.1 0.9 -0.5 -1.0 -1.3 1.2 -0.6 -0.0 0.6 -0.7 -0.1 -0.9 -1.0 -0.9 -0.4 1.0 0.0 0.6 -1.1 0.8 -1.2 0.8 -0.3 -0.0
Medication: Bendroflumethiazide 0.7 1.0 3.4 0.5 1.0 1.1 1.1 0.5 1.1 1.2 1.2 1.5 -0.7 -1.2 -0.6 1.0 0.4 -1.1 1.0 1.1 0.0 -1.1 0.8 0.6 -1.4 1.2 0.0 0.9 1.0 1.1 -1.4 -0.9 -1.9 -0.8 0.9 -1.4 -0.6 -1.2 0.7 0.1
Medication: Paracetamol 0.4 0.6 2.7 0.4 1.1 1.0 0.9 0.1 0.8 0.8 1.1 1.6 -0.7 -0.9 1.0 -0.2 0.4 -1.0 0.7 0.6 -0.1 -0.8 0.7 0.3 -1.1 0.8 -0.6 0.5 1.1 0.9 -0.2 -0.4 -0.3 -0.5 0.9 -1.0 1.0 -0.8 0.0 -0.5
Medication: Lisinopril 0.3 0.5 1.7 -1.0 -0.1 -0.9 -0.6 -0.7 -0.5 -0.8 -0.6 -0.6 0.3 0.4 -0.7 -0.8 -0.5 0.3 -0.5 -0.7 -1.3 1.0 -1.1 -0.7 0.3 -0.6 -0.4 -0.8 -0.6 -0.6 0.3 1.0 -0.8 0.8 -0.6 0.6 -0.1 0.5 -0.4 0.1
Medication: Atorvastatin 0.4 0.5 3.5 -0.9 0.2 -0.8 -0.5 -1.0 0.1 -0.2 -0.2 -0.6 -0.1 0.0 -1.0 -0.4 -1.4 0.7 -0.2 -0.5 -1.1 0.5 -0.2 -0.3 0.2 -0.1 -0.4 -0.4 -0.9 -0.7 -1.9 0.5 -1.2 0.4 -1.0 0.3 -1.4 0.4 0.2 -0.4
Illnesses of father: High blood pressure 0.1 0.1 0.7 -0.2 -0.0 -0.5 -0.3 0.2 0.1 -0.1 0.0 -0.5 0.3 -0.1 0.0 -0.2 -0.4 0.3 0.1 0.0 -0.4 0.5 -0.4 -0.3 -0.2 -0.1 0.5 -0.2 -0.6 -0.5 -0.3 0.1 0.3 -0.2 -0.5 0.1 -0.8 0.1 -0.1 -0.0
Alcohol drinker status: Never 0.2 0.2 1.5 0.2 1.2 -0.3 -0.1 0.4 0.6 0.1 0.5 0.5 -0.4 -0.6 -0.3 -0.3 -0.2 -0.3 0.4 0.0 -0.9 0.2 -0.4 0.0 -0.7 0.1 0.0 0.2 0.1 -0.0 0.5 0.8 -0.4 -0.2 0.1 0.1 0.8 0.2 0.5 0.7
Ever smoked 0.3 0.5 4.4 -0.7 0.3 -0.0 -0.0 -0.8 0.2 0.3 0.5 1.7 -0.7 -0.3 -1.1 -0.7 -0.4 -0.5 0.1 0.2 -1.1 -0.3 -0.6 -0.6 -0.6 0.0 -1.3 -0.5 0.2 -0.2 -0.8 -0.6 -2.1 -0.0 0.0 -0.8 -0.5 -0.8 -0.5 -0.9
Basal metabolic rate 1.8 9.9 17.8 3.1 4.2 3.4 4.0 2.1 3.9 3.9 4.0 2.7 -2.8 -4.0 1.1 2.3 1.9 -3.5 3.6 3.2 1.5 -3.9 3.3 3.3 -4.1 3.5 1.6 3.6 3.6 3.6 -1.0 -3.2 -1.7 -3.1 3.5 -3.6 1.0 -3.4 2.6 2.4
Leg fat percentage (left) 0.3 1.2 3.3 1.1 1.3 1.7 1.4 0.6 1.0 1.3 1.3 1.8 -1.0 -1.1 1.2 1.0 0.2 -1.3 1.1 1.7 1.1 -1.3 1.3 0.2 -1.1 1.6 -0.0 0.9 1.3 0.8 -0.6 -1.4 -0.1 -0.9 1.1 -1.4 -0.6 -1.2 -0.2 0.4
Arm fat-free mass (left) 1.5 7.6 14.7 2.6 3.7 2.9 3.4 1.7 3.4 3.4 3.6 2.5 -2.4 -3.6 0.7 1.9 1.6 -3.0 3.2 2.4 1.1 -3.7 2.6 2.5 -3.8 3.0 1.4 3.2 3.3 3.2 -1.2 -3.0 -1.8 -2.7 3.1 -3.3 0.8 -3.2 2.2 1.7
Number of operations (self-reported) 0.1 0.1 0.7 -0.1 -0.5 -0.3 -0.4 -0.5 0.0 -0.1 -0.0 -0.8 -0.4 0.0 0.1 -0.3 -0.1 0.1 -0.0 -0.6 -0.2 0.2 -0.4 -0.1 -0.0 -0.2 0.1 0.1 0.1 0.2 0.4 0.3 -0.5 0.1 0.1 0.2 0.6 0.2 -0.0 -0.1
Average weekly beer plus cider intake 0.1 0.2 1.2 0.1 -0.2 0.7 0.3 0.6 -0.2 0.2 0.3 -0.3 -0.2 -0.1 0.5 0.5 0.1 -0.3 0.1 0.6 0.9 -0.7 0.2 -0.2 -0.2 0.4 -0.5 -0.0 -0.0 -0.1 -0.2 -0.4 0.4 -0.3 -0.1 -0.4 -1.0 -0.1 -1.1 -0.7
Irritability 0.8 1.4 4.4 -0.8 -1.2 -1.2 -1.5 -0.6 -1.7 -1.3 -1.5 -2.1 1.6 1.6 -1.2 -0.5 -0.3 1.4 -1.4 -0.2 0.4 1.3 -1.0 -0.5 1.7 -1.2 -0.2 -0.9 -1.5 -1.5 -0.3 1.0 0.9 1.2 -1.3 1.4 -0.8 1.3 -0.9 -0.7
Risk taking 0.1 0.2 1.4 0.1 0.3 -0.0 -0.3 0.7 -0.3 -0.4 -0.3 0.1 0.1 0.0 1.1 0.1 0.1 -0.5 -0.1 0.4 0.2 0.4 -0.4 -0.6 -0.0 0.5 -0.3 -0.1 -0.3 -0.0 0.1 0.5 1.2 -0.0 -0.0 -0.0 0.4 0.2 -0.5 0.4
Ever had prostate specific antigen (PSA) test 0.8 0.9 3.9 -0.2 -1.1 -1.3 -1.1 -0.5 -0.6 -1.0 -1.6 -2.0 0.6 0.9 0.2 -1.0 -0.6 1.2 -0.8 -0.9 -0.2 1.4 -0.7 -0.2 1.2 -1.0 1.2 -0.2 -0.6 -1.1 -0.1 1.2 1.4 0.6 -0.6 1.3 -0.0 1.1 -0.0 0.5
Fractured/broken bones in last 5 years 0.4 0.5 2.4 -1.0 -0.2 -0.3 -0.2 -1.5 -0.6 -0.5 -0.2 -0.1 0.3 0.5 -0.6 -0.8 -0.6 0.0 -0.5 -0.7 -1.5 0.7 -0.7 0.0 0.2 -1.1 -1.5 -1.3 -0.3 -0.5 1.0 0.5 -0.5 0.7 -0.4 0.0 -1.1 0.0 -1.3 -0.4
Age started oral contraceptive pill 0.3 0.3 1.7 0.6 0.6 0.8 0.0 0.5 -0.2 -0.0 -0.2 -0.3 0.3 0.4 0.1 1.1 1.1 -0.7 -0.0 1.2 0.2 -0.1 0.6 0.4 0.5 0.1 -0.2 0.1 0.6 0.2 0.8 -0.0 -0.5 0.1 0.7 -0.1 1.0 -0.0 1.0 1.3
Diastolic blood pressure, automated reading 0.7 2.1 5.2 1.9 1.9 1.5 1.8 1.1 1.5 1.7 1.6 1.4 -0.8 -1.4 1.2 1.3 1.0 -1.5 1.6 1.7 1.8 -1.7 1.6 1.0 -1.5 2.3 1.4 1.7 1.4 1.9 0.0 -1.4 0.7 -1.5 1.7 -1.3 0.4 -1.3 0.8 1.3
Ever depressed for a whole week 0.2 0.2 2.2 -0.5 -0.2 -0.0 -0.1 0.1 -0.2 -0.2 0.2 1.1 0.1 0.4 -0.1 -0.4 -0.3 0.2 -0.4 -0.3 -0.2 0.1 -0.4 -0.0 0.0 -0.2 -1.5 -0.4 -0.5 -0.2 -0.0 0.2 -0.2 0.4 -0.4 0.0 -0.8 0.2 -0.8 -0.9
Unable to work because of sickness or disability 0.1 0.2 0.7 0.7 0.3 0.4 0.4 -0.2 0.3 0.4 0.6 -0.1 -0.2 -0.3 0.9 -0.0 0.3 -0.3 0.3 -0.0 0.8 -0.4 0.2 0.6 -0.5 -0.1 -0.6 0.6 0.3 0.4 0.1 -0.2 0.4 -0.4 0.3 -0.1 0.1 -0.0 -0.5 -0.4
Commuting to job workplace: Cycle 0.9 1.1 6.6 0.8 -0.5 0.3 -0.3 1.1 -0.5 -0.3 -0.8 -1.6 0.4 0.6 1.5 1.7 1.9 -0.2 0.1 0.4 1.7 0.5 0.6 0.4 1.1 0.3 2.5 0.4 -0.1 0.3 1.0 0.4 2.6 -0.2 0.2 0.6 1.3 0.5 1.0 1.8
Myopia 0.3 0.4 2.1 -0.2 0.7 -0.5 -0.3 -0.2 -0.2 -0.3 -0.5 -0.3 0.4 0.5 0.1 -0.5 -1.3 0.4 -0.4 -0.3 -0.8 0.7 0.6 0.9 0.9 -0.4 -1.4 -0.5 -0.8 -0.8 0.2 1.0 0.2 0.5 -0.7 0.8 0.0 0.8 0.1 0.4
Vascular/heart problems diagnosed by doctor 0.2 0.5 2.5 0.2 -1.3 -0.0 -0.5 0.3 -1.1 -0.7 -0.8 -0.2 1.0 1.2 -1.2 -0.3 0.3 0.7 -0.9 0.0 1.3 0.7 0.1 0.5 1.6 -1.0 -0.3 -0.5 -0.6 -0.5 0.7 0.2 0.4 0.9 -0.5 0.9 -0.2 0.9 -0.1 0.3
Cholesterol lowering medication 1.2 1.7 3.7 -1.7 -0.2 -1.3 -1.0 -1.6 -1.0 -1.2 -1.1 -0.7 1.5 1.2 -0.5 -1.5 -1.7 1.1 -1.4 -1.4 -1.9 1.5 -0.8 0.2 1.2 -1.9 -1.6 -1.9 -1.6 -1.4 0.1 1.6 -0.6 1.5 -1.6 1.3 -1.4 1.3 -1.3 -0.6
Medication: Omeprazole (e.g. Zanprol) 0.5 0.6 4.1 -0.3 0.2 0.0 0.3 0.1 0.9 0.8 0.8 0.5 -1.1 -1.0 1.0 0.1 -0.0 -0.0 0.7 -0.3 -0.6 -1.2 0.3 -0.6 -1.1 0.7 -0.7 0.7 0.1 -0.0 -2.0 -1.0 -0.4 -1.0 -0.1 -1.0 -0.4 -0.9 -0.3 -1.7
Pain experienced in last month 0.2 0.3 2.6 0.2 0.1 0.7 0.4 0.1 -0.2 0.0 0.0 0.9 0.0 0.4 0.3 1.1 0.2 -0.8 0.0 1.6 0.4 0.4 0.2 0.1 0.3 0.5 0.5 -0.2 0.0 0.3 0.4 -1.0 0.0 -0.3 0.3 -0.6 -0.3 -0.7 0.3 0.8
Supplements: Calcium 0.4 0.4 1.2 -0.4 -0.9 -0.6 -0.7 -0.3 -0.6 -0.7 -0.5 -0.9 1.1 0.8 -0.5 -0.5 -0.2 0.8 -0.7 -0.6 0.6 0.7 -0.8 -0.2 0.6 -0.3 -0.3 -0.6 -0.9 -0.5 0.5 0.6 0.0 0.7 -0.7 0.9 -1.1 0.9 -0.6 -0.0
Basal cell carcinoma (self-reported) 1.8 2.2 6.6 0.2 1.7 0.9 1.2 0.6 2.2 2.0 2.6 1.0 -1.9 -2.2 -1.2 0.5 0.3 -1.2 1.8 0.5 -1.5 -1.9 1.1 1.0 -2.3 1.0 -1.0 0.8 1.2 1.3 -0.8 -1.7 -2.5 -1.8 1.1 -2.1 -0.2 -2.1 1.3 0.6
Heart attack/myocardial infarction (self-reported) 0.9 1.1 2.8 -0.7 -0.4 -1.5 -1.2 -1.6 -0.8 -1.2 -1.1 -1.1 0.8 0.8 -0.1 -1.1 -1.1 1.3 -1.0 -1.5 -0.5 1.2 -1.1 -0.4 0.8 -1.7 -0.5 -0.6 -1.1 -0.5 -0.1 1.7 1.1 1.2 -1.0 1.4 0.2 1.5 -0.6 -0.8
Deep venous thrombosis (DVT) (self-reported) 2.3 3.0 7.1 0.6 1.9 1.7 1.7 0.4 2.1 2.0 2.2 1.4 -2.5 -2.4 1.3 1.5 1.4 -2.1 2.0 1.6 -0.9 -2.4 1.0 -0.1 -2.6 1.3 0.7 1.5 2.2 1.4 -0.7 -2.2 -1.7 -2.2 1.9 -2.7 1.2 -2.6 1.1 0.2
Heart disease (siblings) 4.8 5.8 13.4 -3.2 -1.3 -3.1 -2.7 -3.3 -1.7 -2.1 -1.8 -0.2 1.6 1.5 -1.6 -2.9 -2.8 2.5 -2.2 -3.3 -3.7 1.7 -2.5 -2.5 1.3 -2.5 -2.6 -2.7 -2.8 -3.1 -1.3 2.6 -1.4 2.3 -3.1 1.8 -1.9 2.0 -2.5 -3.2
Alcohol drinker status: Previous 0.4 0.4 2.0 1.0 0.3 0.6 0.5 0.8 0.5 0.7 0.7 1.1 -0.3 -0.6 -0.3 -0.1 0.1 -0.2 0.4 0.7 1.2 -0.8 0.8 1.0 -0.4 0.5 1.4 0.7 0.3 0.4 0.1 -0.6 -0.2 -0.5 0.4 -0.3 -1.0 -0.1 0.0 0.4
Pack years of smoking 1.4 2.1 8.2 -2.1 -1.0 -1.1 -1.3 -0.9 -1.5 -1.4 -1.0 0.3 1.1 1.3 -1.2 -0.8 -1.6 1.1 -1.4 -0.8 -1.9 1.2 -1.5 -1.4 1.0 -1.7 -2.9 -2.0 -1.7 -2.1 -0.9 1.0 -1.0 1.3 -1.9 0.6 -2.0 0.8 -1.7 -2.0
Impedance of whole body 0.5 2.7 6.8 -1.6 -2.6 -1.6 -2.4 -0.7 -2.1 -2.0 -2.0 -1.4 0.8 2.1 -0.5 -1.0 -1.0 1.8 -1.8 -1.2 -0.4 1.6 -2.2 -2.6 2.1 -1.8 -0.7 -1.9 -1.7 -2.2 -0.2 1.1 1.0 1.3 -1.8 1.5 -1.1 1.5 -1.6 -1.9
Leg fat mass (left) 1.1 4.3 7.7 2.1 2.7 2.7 2.8 1.2 2.3 2.5 2.6 2.5 -1.9 -2.4 1.4 1.8 1.0 -2.4 2.3 2.6 1.4 -2.5 2.5 1.7 -2.4 2.7 0.6 2.1 2.4 2.0 -0.8 -2.3 -0.7 -1.8 2.3 -2.4 -0.4 -2.2 1.0 1.5
Arm predicted mass (left) 1.5 7.5 13.6 2.7 3.6 2.9 3.4 1.9 3.3 3.3 3.4 2.2 -2.4 -3.5 1.1 1.9 1.6 -3.0 3.2 2.4 1.3 -3.6 2.7 2.5 -3.7 3.1 1.5 3.2 3.2 3.2 -1.1 -2.9 -1.3 -2.8 3.1 -3.2 0.9 -3.1 2.2 1.8