Hub : Genes

DHCR24

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0580	0.0250	9.9e-03	0.002	0.002	0.008	0.008	0.000	1.5e-01	1.5e-01	3.0e-02	3.4e-02	2.8e-01
2	GTEx	Brain Hypothalamus	0.4420	0.1230	2.9e-03	-0.013	NA	0.017	NA	-0.006	9.4e-01	NA	1.3e-01	NA	4.7e-01
3	GTEx	Cells Transformed fibroblasts	0.1200	0.0410	1.2e-03	0.064	NA	0.103	NA	0.103	1.5e-05	NA	3.8e-08	NA	3.8e-08
4	GTEx	Esophagus Mucosa	0.1380	0.0500	2.9e-03	0.072	NA	0.023	NA	0.051	1.4e-05	NA	1.0e-02	NA	2.3e-04
5	GTEx	Small Intestine Terminal Ileum	0.3750	0.1450	9.3e-03	0.019	NA	-0.013	NA	-0.012	1.2e-01	NA	9.3e-01	NA	7.6e-01
6	YFS	Blood	0.0572	0.0128	4.3e-14	0.061	0.050	0.054	0.053	0.057	2.4e-19	6.8e-16	4.5e-17	8.9e-17	6.5e-18
7	TCGA	Breast Invasive Carcinoma	0.0267	0.0140	1.6e-03	0.019	0.015	0.021	NA	0.019	5.7e-05	3.7e-04	3.5e-05	NA	8.2e-05
8	TCGA	Lung Adenocarcinoma	0.0523	0.0278	8.8e-04	0.015	0.024	0.037	NA	0.020	6.9e-03	7.9e-04	3.4e-05	NA	1.8e-03

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	0.8	1.2	2.4	-0.2	1.5	-0.7	0.9	-1.0	-0.2	1.5	1.5
Bipolar Disorder or Schizophrenia	0.6	1.4	5.3	0.7	2.3	-0.0	-1.3	-0.3	-1.2	1.4	0.3
Depressed Affect (Nagel 2018)	0.2	0.4	2.2	1.5	0.5	0.3	-0.3	-0.4	0.1	-0.3	-0.5
Depression (Nagel 2018)	0.9	1.3	5.5	1.7	2.3	0.3	0.9	0.8	0.5	-0.5	0.0
Intelligence (Savage-Jansen 2018)	0.1	0.3	0.8	0.9	0.5	0.3	-0.6	0.4	-0.3	0.9	0.4
Neuroticism (Nagel 2018)	0.5	1.1	3.5	1.9	1.2	0.1	-1.6	0.4	-0.8	-0.6	-0.6
Schizophrenia (2018)	0.8	1.7	5.9	1.2	1.8	0.6	-2.4	0.4	-1.3	0.5	-0.6
Schizophrenia vs Biploar Disorder	0.3	0.4	0.9	-0.5	0.2	1.0	0.6	0.8	0.8	-0.4	-0.7
Worry (Nagel 2018)	0.7	1.5	5.3	1.6	2.3	0.2	-1.3	0.4	-0.5	-0.6	-1.2
Alzheimer’s Disease (in mother)	0.4	0.5	1.6	1.1	-0.6	0.4	-0.2	-0.2	0.4	0.4	-1.3
Alzheimer’s Disease (in father)	0.3	0.4	1.6	1.3	-0.5	0.2	-0.3	-0.4	0.3	-0.8	-0.1
Alzheimer’s Disease (including proxy)	0.5	0.7	1.8	1.3	0.2	0.6	-1.1	0.3	0.2	0.7	-1.1
Crohns Disease (2017)	1.7	3.7	7.6	-2.0	-1.9	-2.5	-2.0	1.0	-2.8	1.4	1.1
Irritable Bowel Disease (IBD)	1.5	3.5	8.5	-2.5	-1.5	-2.9	-1.5	-0.1	-2.4	0.7	1.5
Ulcerative Colitis (UC)	0.9	1.6	4.6	-2.0	-0.8	-2.1	-0.6	-0.8	-1.2	-0.3	1.1
Major Depression (MDD)	0.9	1.1	4.3	2.1	1.8	0.6	-0.3	-0.1	0.3	-0.4	0.3
Reaction Time	0.4	0.8	1.5	-0.3	-0.2	-1.2	-0.5	0.9	-1.2	-1.1	0.9
Verbal and Numeric Reasoning (VNR)	0.3	0.8	1.9	1.2	0.9	1.1	-0.6	-1.4	-0.3	0.3	-0.5
Breast Cancer	0.8	1.9	5.2	-0.8	-0.7	-1.1	-2.3	1.0	-1.7	1.9	-0.2
Ovarian Cancer	1.2	1.5	7.2	-0.3	0.1	0.2	1.9	2.7	0.9	-0.6	0.1
Prostate Cancer	0.2	0.3	0.6	0.5	0.3	0.8	0.7	-0.7	0.7	-0.1	-0.4
Age at First Birth	1.2	1.8	7.3	-0.2	2.7	-0.8	-0.5	-1.2	-1.2	-0.1	1.8
Bipolar Disorder (2011)	1.0	0.9	2.1	-1.1	-0.7	-1.3	0.5	-0.9	-0.4	0.9	1.5
Body Mass Index (BMI) (2010)	1.4	2.0	7.6	-1.0	2.8	-1.0	-1.6	1.1	-1.2	-1.0	-0.0
Coronary Artery Disease (CAD)	0.3	0.3	0.9	-0.9	0.6	-0.7	0.1	-0.2	-0.9	0.4	-0.0
Crohns Disease (2012)	0.9	1.5	3.3	-1.0	-0.8	-1.7	-0.6	1.8	-1.2	1.3	0.7
Mean Putamen Volume	1.4	1.6	4.8	2.1	-1.1	1.3	-0.1	-2.2	1.0	-0.1	-0.1
Fasting Glucose	0.8	0.9	2.7	0.8	-0.7	1.2	-0.8	-1.0	0.1	0.7	-1.7
HbA1C	0.4	0.4	1.2	-0.8	0.2	-0.4	-0.5	-0.3	-0.5	-1.1	0.8
HDL Cholesterol	1.0	1.6	2.7	1.3	1.2	1.6	1.0	-0.5	1.4	1.2	-1.5
LDL Cholesterol	1.3	2.1	5.8	-0.8	-2.4	-1.0	-1.4	-2.4	-1.3	-0.1	0.2
Lupus	1.5	2.3	4.2	2.1	2.1	1.9	0.3	-1.2	1.0	-1.8	-0.5
Neuroticism (2016)	1.0	1.4	4.8	2.2	-0.7	0.9	1.0	-0.6	0.8	-1.5	-1.1
Primary Biliary Cirrhosis	0.7	1.0	2.5	0.3	1.2	1.3	0.7	1.6	1.0	-0.2	-1.1
Rheumatoid Arthritis	0.3	0.4	1.3	-0.2	-0.6	1.1	-0.3	0.3	0.6	0.6	-0.7
Schizophrenia (2014)	0.3	0.7	2.0	1.1	1.2	0.4	-1.4	-0.1	-0.8	0.6	-0.3
Triglycerides	0.5	0.9	4.1	0.1	-1.2	-0.3	-0.3	-0.9	-0.7	-2.0	0.2
Type 2 Diabetes (T2D) (2012)	0.4	0.4	1.1	-1.0	0.0	-1.1	-0.3	0.3	-0.3	-0.3	0.9
Ulcerative Colitis	0.9	1.3	3.6	-1.9	0.6	-1.9	0.7	0.5	-0.2	-0.4	1.6
Blood Eosinophil Count	0.2	1.6	4.1	2.0	1.9	-0.3	-1.1	-1.7	-0.7	0.8	0.1
Blood Platelet Count	0.1	1.7	5.1	0.9	2.2	0.1	-2.2	0.0	-1.4	0.9	0.5
Blood Red Count	0.1	0.7	1.9	0.1	1.4	0.1	1.0	1.2	0.8	-0.3	0.5
Blood White Count	0.3	1.9	5.5	-0.3	1.6	-1.5	-2.4	0.8	-1.8	0.7	0.5
Heel T-Score	0.7	5.7	22.9	0.6	-4.8	2.0	2.1	-2.5	2.1	1.2	-1.4
BMI	0.2	0.9	1.8	0.3	0.1	-1.3	-0.5	0.6	-1.4	-1.1	1.3
Height	0.5	10.6	28.4	2.7	-0.2	3.0	5.3	-0.6	4.8	-4.0	-0.6
Waist Hip Ratio (WHR)	0.2	0.8	1.6	0.3	1.0	1.3	-0.9	-0.1	0.7	-1.0	-1.3
Systolic Blood Pressure	0.2	1.2	4.6	-1.5	-0.7	0.5	-0.6	-2.1	0.3	-0.9	-0.6
Smoking Status	0.8	1.9	4.4	-0.8	-0.6	-1.8	0.1	1.7	-0.8	2.1	1.8
Allergy or Eczema	0.1	0.2	1.1	-0.3	-0.6	-0.2	0.2	0.4	0.3	1.1	0.2
Cardiovascular Disease	0.6	2.0	9.5	0.4	-2.3	0.3	-0.5	-3.1	-0.6	-0.5	0.4
Hypothyroidism (self reported)	0.1	0.3	1.0	0.5	1.0	0.5	0.2	0.5	0.4	-0.5	-0.4
Respiratory disease	0.2	0.4	1.0	0.0	0.7	-0.5	-0.9	-0.2	-1.0	0.7	-0.3
Type 2 Diabetes (T2D) (2018)	0.5	0.9	2.7	-0.6	1.6	-1.1	-0.3	-0.2	-1.0	0.3	1.4
Lung FEV1/FVC ratio	0.1	0.5	2.4	-0.3	-0.5	-0.7	0.6	-0.8	-0.1	-1.6	0.1
Lung FVC	0.1	0.5	2.0	0.4	-1.4	0.0	-0.1	1.0	-0.1	0.8	0.3
Neuroticism	0.5	1.2	3.5	1.9	1.2	-0.4	-1.4	0.4	-0.8	-1.4	0.1
Chronotype (morning person)	0.2	0.4	0.9	-0.4	-0.9	0.0	-1.0	0.8	-0.6	-0.6	-0.2
Hair Pigment	0.0	1.1	3.4	0.3	-0.1	0.8	1.8	-1.1	1.5	-0.9	0.7
Tanning	0.0	0.5	1.4	-1.1	-0.2	-0.8	1.2	0.2	0.2	-0.5	0.8
Hand grip strength (left)	0.1	0.4	0.9	-0.2	-0.1	0.3	0.6	-0.9	0.8	-1.0	-0.4
Number of treatments/medications taken	0.3	0.6	1.8	-1.3	0.9	-1.0	0.2	0.5	-0.6	0.5	0.6
Average weekly spirits intake	1.1	1.4	5.6	-2.4	0.9	-1.6	0.4	-0.8	-0.4	0.7	0.8
Sensitivity / hurt feelings	1.0	1.6	3.8	-0.1	1.2	-1.2	-1.9	1.7	-1.8	-0.2	0.7
Frequency of depressed mood in last 2 weeks	1.4	1.9	5.9	1.1	2.4	-0.5	0.9	2.4	0.0	-1.2	0.4
Hearing difficulty/problems: Yes	0.3	0.5	1.5	0.5	0.2	-1.2	-0.4	0.4	-0.8	0.6	0.9
Relative age of first facial hair	1.3	2.8	5.1	-0.8	-0.5	-2.3	-1.9	0.3	-2.0	2.1	1.9
Other serious medical condition/disability diagnosed by doctor	3.4	4.4	8.5	-1.1	2.9	-2.8	-1.1	1.9	-2.5	-1.6	2.0
Ever used hormone-replacement therapy (HRT)	0.6	0.7	3.2	0.5	0.4	0.7	0.5	-1.0	0.2	0.5	-1.8
Ever had hysterectomy (womb removed)	0.8	0.9	4.4	1.1	-0.1	0.4	0.8	-2.1	0.4	-0.3	-0.6
Systolic blood pressure, automated reading	0.6	1.8	5.8	-2.4	-1.8	-0.7	-1.4	-1.0	-0.9	0.9	-0.3
Eye problems/disorders: Diabetes related eye disease	0.5	0.6	1.3	-0.4	0.1	-0.8	-0.9	0.2	-1.1	1.1	0.7
Angina	1.1	1.4	3.4	0.2	-0.2	0.2	-1.6	-1.8	-0.6	1.8	-1.3
Medication for hormone replacement therapy	0.3	0.4	1.4	0.1	0.4	-0.9	0.2	1.2	-0.6	-0.0	-0.2
Vitamin and mineral supplements	1.1	1.6	5.6	0.2	-0.3	-0.7	-1.8	-2.4	-1.2	1.3	-0.2
Supplements: Zinc	0.4	0.5	1.3	0.2	-1.1	1.0	-0.2	-0.4	0.5	-1.0	-0.4
Medication: Co-codamol	1.4	1.6	2.9	1.2	0.5	1.6	0.7	0.7	1.4	1.6	-1.7
Medication: Metformin	1.6	2.3	4.3	-0.9	1.5	-2.0	-1.4	-0.7	-2.1	1.3	1.8
Diabetes (father)	0.4	0.5	1.8	-0.3	-0.0	-0.6	-0.8	-0.1	-0.7	-1.4	0.7
Diabetes (mother)	1.2	1.5	9.5	-0.2	0.0	0.2	-0.6	1.1	-0.3	3.1	-0.8
Severe depression (siblings)	0.7	0.8	2.6	0.6	0.6	-1.2	-0.7	0.2	-1.6	1.0	0.7
Pack years adult smoking proportion	0.2	0.3	1.6	0.5	0.4	0.4	-0.5	0.1	-0.5	1.3	-0.0
Impedance of leg (right)	0.1	0.4	1.4	0.3	-0.5	0.7	0.6	-0.1	1.2	0.7	-0.7
Leg fat-free mass (left)	0.1	0.7	2.5	0.3	0.6	-1.0	0.2	-0.2	-0.6	-1.6	1.2
Trunk fat percentage	0.3	1.3	4.0	0.1	-0.6	-1.2	-2.0	0.4	-1.8	0.8	0.6
Hand grip strength (right)	0.1	0.2	1.5	-0.3	0.0	-0.3	-0.1	-1.2	0.1	0.2	0.4
Townsend deprivation index at recruitment	0.6	0.9	2.3	-1.1	0.1	-1.0	1.1	1.5	-0.3	-1.0	0.7
Current tobacco smoking	1.2	2.0	4.6	-1.0	1.4	-2.1	-0.9	1.1	-1.6	1.1	1.7
Average weekly fortified wine intake	0.6	0.7	3.5	0.2	0.1	1.0	0.2	-0.2	0.8	0.4	-1.9
Maternal smoking around birth	0.5	0.7	2.7	1.6	0.3	1.0	-0.2	-1.1	-0.1	0.2	-0.7
Fed-up feelings	0.2	0.3	0.7	0.8	-0.1	-0.8	0.2	0.5	-0.4	-0.8	0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	1.0	6.0	0.4	2.5	-0.7	0.2	0.6	-0.5	0.6	0.4
Relative age voice broke	0.4	0.6	2.8	1.7	-0.7	0.5	-0.1	-0.7	0.5	0.1	-0.1
Taking other prescription medications	0.3	0.5	1.2	-1.1	0.6	-0.8	0.3	0.9	-0.6	-0.0	0.6
Age when periods started (menarche)	0.4	1.0	2.2	-0.8	-1.5	-0.6	1.4	-1.1	0.6	-1.2	0.6
Bilateral oophorectomy (both ovaries removed)	0.3	0.3	1.9	-0.1	-0.7	-0.2	0.1	-1.4	-0.5	0.1	-0.2
Heel bone mineral density (BMD) T-score, automated (left)	1.4	3.2	12.3	-2.4	-3.5	-1.4	-0.1	0.7	-1.1	1.3	1.4
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	0.7	0.7	0.1	0.1	0.7	0.9	0.3	-0.6	0.1
Qualifications: CSEs or equivalent	1.3	1.8	3.8	-0.4	0.8	-1.4	-1.9	-1.5	-2.0	-0.5	1.3
Serious illness, injury or assault to yourself	2.4	2.9	9.3	-1.3	1.5	-1.3	1.7	3.1	-0.0	-1.3	1.8
High blood pressure	0.3	1.0	2.8	-0.5	-0.9	-1.0	-0.8	-0.3	-1.7	0.7	1.3
Hayfever, allergic rhinitis or eczema	0.2	0.3	1.2	-1.1	-0.2	-0.3	0.6	0.5	0.5	-0.0	0.7
Multivitamins +/- minerals	0.4	0.5	2.0	0.2	0.3	0.1	1.4	1.3	0.2	-0.5	0.4
Stomach or abdominal pain in last month	0.7	0.8	3.4	0.9	1.9	-0.3	-0.5	0.9	-0.9	0.2	0.6
Supplements: Glucosamine	0.4	0.6	2.5	0.3	-0.9	0.2	1.6	-0.4	1.0	-0.2	0.2
Diverticular disease/diverticulitis (self-reported)	2.6	3.1	6.8	-1.1	0.2	-1.5	-2.6	1.4	-2.5	2.4	-0.1
Medication: Atenolol	0.2	0.3	1.1	0.1	-0.8	0.3	-0.3	-0.1	-0.1	0.4	-1.1
Medication: Levothyroxine sodium	0.2	0.4	1.7	-0.0	1.0	0.5	0.2	0.1	0.2	0.4	-1.3
Sitting height	0.6	4.5	15.0	0.5	1.6	0.4	3.9	-0.3	2.4	-3.4	0.9
Chronic bronchitis/emphysema (father)	0.5	0.6	3.4	1.8	0.1	0.5	0.9	-0.1	0.6	0.1	0.4
High blood pressure (mother)	0.7	0.9	3.2	-1.1	0.3	0.5	0.8	-0.6	0.7	1.8	-1.0
Body mass index (BMI)	0.4	1.9	5.6	-0.1	-0.3	-1.8	-2.1	0.3	-2.4	0.5	1.1
Impedance of leg (left)	0.0	0.2	0.8	0.3	-0.0	0.4	0.4	0.1	0.9	-0.0	-0.1
Leg predicted mass (left)	0.1	0.7	2.5	0.4	0.7	-0.9	0.2	-0.3	-0.5	-1.6	1.1
Trunk fat mass	0.2	0.9	2.2	0.3	-0.3	-1.3	-1.3	0.4	-1.5	0.1	1.1
Waist circumference	0.2	0.6	1.7	0.4	-0.3	-1.0	-1.2	-0.0	-1.3	0.4	0.5
Number of incorrect matches in round	0.2	0.3	0.9	0.9	-0.2	0.3	-0.4	0.7	-0.3	-0.9	-0.0
Past tobacco smoking	0.7	1.3	4.8	0.5	0.8	1.5	-0.1	-0.6	0.9	-2.2	-1.0
Alcohol usually taken with meals	1.1	1.7	4.4	1.1	-0.8	1.6	1.9	-0.2	2.1	-0.5	-1.1
Nervous feelings	0.3	0.5	2.1	0.1	0.5	-0.5	-0.4	0.6	-0.8	1.4	0.3
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.8	2.1	1.0	0.8	-0.6	1.3	0.8	0.5	-1.4	0.2
Hearing difficulty/problems with background noise	0.4	0.6	2.1	-0.1	-0.1	0.1	-0.7	-1.5	-0.4	1.1	-0.8
Hair/balding pattern: Pattern 2	0.6	0.7	3.2	0.7	-1.8	0.9	0.4	-0.3	0.8	-0.2	-0.6
Had menopause	0.6	0.7	1.7	0.3	-0.1	1.3	1.2	-0.8	1.3	0.2	-0.5
Had other major operations	0.7	0.9	2.7	-1.1	1.6	-1.0	0.2	0.1	-0.8	-0.7	1.2
Forced vital capacity (FVC)	0.1	0.3	0.7	0.8	-0.5	-0.2	0.7	0.3	0.3	-0.5	0.6
Heel bone mineral density (BMD) T-score, automated (right)	1.2	2.7	8.9	-1.6	-3.0	-1.4	-0.9	0.9	-1.5	1.8	0.9
Ever unenthusiastic/disinterested for a whole week	1.3	1.6	5.6	0.8	2.4	-0.9	-0.4	0.7	-0.9	-1.7	0.9
Qualifications: None of the above	0.4	0.9	2.8	-1.1	-0.7	-1.7	0.2	0.7	-0.9	0.6	1.2
Financial difficulties in last 2 years	1.0	1.3	4.7	1.1	1.8	-0.2	0.5	0.5	-0.0	-2.2	1.0
Mouth/teeth dental problems	0.2	0.4	0.9	-0.0	0.5	1.0	-0.7	0.4	-0.1	0.6	-0.9
Heart attack	0.6	0.7	1.4	1.2	0.8	1.1	-0.2	-0.1	0.9	-1.0	-0.8
Allergy	0.1	0.3	1.0	0.5	-0.1	1.0	-0.4	-0.3	0.1	-0.0	-1.0
Pain all over the body in last month	0.5	0.6	2.3	-1.0	1.0	-0.1	0.1	-0.1	-0.5	-1.5	0.4
Diabetes (self-reported)	0.3	0.5	3.0	0.0	1.7	0.3	-0.5	-0.6	-0.4	0.5	0.1
Hayfever/allergic rhinitis (self-reported)	1.9	2.5	6.9	1.6	0.5	2.6	0.5	-0.5	1.9	-0.2	-2.4
Medication: Ramipril	0.4	0.5	2.8	-0.5	1.7	0.1	-0.7	-0.6	-0.4	-0.2	0.3
Medication: Simvastatin	0.6	0.8	2.5	-0.2	-1.4	-0.8	-0.4	-1.6	-0.7	0.8	-0.3
Fluid intelligence score	0.2	0.5	1.1	1.0	0.9	1.0	0.3	-0.3	0.4	-0.2	-0.5
Illnesses of siblings	1.5	2.2	9.4	-1.4	1.2	0.7	1.0	-1.0	1.4	-3.1	-0.1
Neuroticism score	0.5	1.0	2.3	0.8	0.8	-1.2	-1.5	0.8	-1.5	-0.2	0.3
Weight	0.2	0.9	2.2	0.5	0.3	-1.5	-0.6	-0.1	-1.3	-0.6	1.5
Impedance of arm (right)	0.2	0.9	3.1	-0.4	-1.4	0.9	-0.3	-0.4	0.6	1.8	-0.8
Arm fat percentage (right)	0.5	2.0	5.2	-0.3	-0.1	-1.6	-2.3	0.8	-2.2	1.2	0.9
Trunk fat-free mass	0.3	1.9	6.2	1.0	1.4	-0.3	1.9	-0.2	0.8	-2.5	1.2
Hip circumference	0.1	0.5	1.1	0.9	-0.2	-0.9	-0.8	-0.1	-1.1	-0.1	0.9
Time employed in main current job	0.4	0.5	1.2	0.6	1.1	-0.7	-0.2	0.2	-0.2	-1.0	0.9
Alcohol intake versus 10 years previously	0.9	1.4	6.9	-1.4	0.3	-0.7	-0.5	2.6	-1.1	0.1	0.6
Father’s age at death	0.5	0.6	1.5	-0.7	0.6	1.2	0.5	-0.1	1.0	0.1	-1.2
Worrier / anxious feelings	0.3	0.6	1.1	1.1	0.0	-0.6	-1.0	1.1	-1.0	-0.7	-0.1
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.6	3.0	-0.4	1.7	-0.6	-0.7	0.3	-0.7	-0.4	-0.1
Falls in the last year	0.4	0.5	2.9	-0.3	-1.7	-0.2	0.2	0.8	-0.0	0.5	0.2
Hair/balding pattern: Pattern 3	0.2	0.3	1.1	0.3	-0.7	0.3	-0.1	-0.4	0.5	-0.2	-1.1
Number of live births	0.6	0.9	2.5	1.2	1.6	-0.4	-0.3	-0.4	-0.6	-0.7	1.4
Forced expiratory volume in 1-second (FEV1)	0.1	0.2	0.6	0.1	-0.5	-0.7	0.3	0.3	-0.1	-0.4	0.5
Pulse rate	0.9	1.5	6.7	-0.3	2.6	-0.4	0.4	2.0	0.2	-0.2	0.8
Happiness	1.6	2.0	8.1	0.6	0.5	0.4	2.8	0.6	1.6	-2.0	0.0
Noisy workplace	0.4	0.5	1.5	0.2	0.5	-0.3	-1.0	-1.2	-0.6	0.9	0.1
Qualifications: A levels/AS levels or equivalent	1.4	3.1	8.1	2.6	1.2	2.9	0.2	-0.4	1.8	-1.4	-1.8
Serious illness, injury or assault of a close relative in last 2 years	0.8	1.0	1.7	0.2	-1.1	-1.1	-1.1	-1.2	-1.3	0.4	0.8
Mouth/teeth dental problems: Dentures	0.3	0.6	1.9	-1.1	0.1	-0.7	-0.6	0.6	-0.3	1.4	-0.4
Asthma	0.1	0.2	0.3	0.4	0.4	-0.1	-0.4	-0.5	-0.5	0.2	-0.3
Medication: Ibuprofen (e.g. Nurofen)	0.1	0.2	0.5	-0.4	0.4	-0.7	0.4	-0.0	-0.4	0.4	0.4
Medication: Cholesterol lowering	1.2	1.8	7.4	0.9	-1.6	0.3	0.4	-2.7	0.6	-1.8	-0.1
Depression (self-reported)	0.5	0.6	1.8	1.3	0.7	0.9	-0.3	-0.2	-0.0	1.2	-0.4
Medication: Lansoprazole	0.4	0.5	1.8	0.0	-0.2	0.5	-1.0	-1.4	-0.4	-0.5	0.5
Prospective memory result	0.7	0.8	3.1	-0.9	-0.2	-0.6	0.8	1.8	0.6	0.4	1.0
Lung cancer (father)	0.8	0.9	4.5	2.1	-0.3	1.1	0.1	-0.8	0.8	0.1	-0.4
Illnesses of mother	1.3	1.7	3.6	-0.5	1.1	-1.2	0.0	1.9	-0.8	-1.8	1.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.4	1.2	1.0	-0.2	0.0	0.4	1.1	0.4	-0.6	-0.5
Pulse wave Arterial Stiffness index	0.4	0.5	1.7	0.3	-1.3	0.4	0.4	-0.6	0.6	0.7	-0.5
Impedance of arm (left)	0.3	1.3	3.2	0.2	-1.0	1.6	-0.6	-0.6	0.9	1.8	-1.4
Arm fat mass (right)	0.3	1.3	3.9	0.1	0.2	-1.6	-1.8	0.2	-2.0	0.2	1.0
Trunk predicted mass	0.4	2.0	6.6	1.1	1.5	-0.3	2.0	-0.2	0.8	-2.6	1.3
Standing height	0.3	2.7	7.2	1.1	1.2	0.6	2.7	-1.3	2.1	-2.3	0.6
Length of working week for main job	0.7	0.8	3.7	-0.2	1.9	-0.7	0.3	-0.4	-0.5	-1.2	0.5
Exposure to tobacco smoke at home	0.9	1.0	2.4	-0.7	0.8	-1.1	-1.2	-0.8	-1.5	-0.5	1.0
Breastfed as a baby	0.2	0.2	0.5	0.3	-0.6	-0.2	0.7	-0.0	0.3	-0.7	-0.5
Tense / ‘highly strung’	0.6	1.1	2.2	1.2	1.4	0.1	1.0	0.7	0.9	-1.5	-0.6
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.3	1.6	1.3	0.7	0.5	-0.2	0.2	-0.3	0.3	-0.0
Hair/balding pattern: Pattern 4	0.7	1.7	5.0	1.2	1.1	0.6	2.2	0.4	0.8	-1.7	1.2
Birth weight of first child	0.4	0.7	2.2	-0.8	1.5	-0.5	0.1	-0.7	-0.3	-0.5	1.2
Peak expiratory flow (PEF)	0.6	1.3	3.7	-1.0	-0.2	-1.9	-0.6	0.2	-1.4	-1.3	1.3
Pulse wave reflection index	1.6	2.0	6.5	0.7	-2.5	1.0	1.7	-1.6	1.4	0.0	-0.6
Ever highly irritable/argumentative for 2 days	1.1	1.3	2.9	1.6	1.5	0.4	0.2	-1.7	0.3	-1.4	0.4
Loud music exposure frequency	2.0	2.1	5.8	-0.3	2.0	-1.3	-1.5	-0.5	-1.6	2.4	0.8
Qualifications: O levels/GCSEs or equivalent	1.1	1.7	3.4	1.8	1.3	1.9	-0.5	-0.9	1.1	-1.0	-1.3
Mouth/teeth dental problems: Bleeding gums	0.2	0.3	1.0	-0.2	-1.0	-0.9	0.2	-0.4	-0.3	-0.2	0.2
Blood clot in the leg (DVT)	1.1	1.4	3.5	0.8	-1.3	0.7	1.8	0.1	1.9	-0.3	-1.2
Medication: Paracetamol	1.0	1.7	3.7	-0.7	1.4	-1.3	-1.8	0.9	-1.9	0.0	1.1
Headache pain in last month	0.7	1.2	3.4	-0.7	1.9	-0.9	-1.5	1.2	-1.0	0.2	-0.0
Medication for cholesterol, blood pressure or diabetes	0.9	1.5	6.8	-1.1	0.8	0.2	0.4	2.6	0.7	1.4	-1.0
Glaucoma (self-reported)	0.3	0.4	1.0	0.9	-0.3	0.8	0.3	-1.0	0.3	0.1	-0.5
Gout (self-reported)	0.6	0.8	3.5	-0.2	-1.9	0.6	-0.8	0.4	0.2	1.0	-0.8
Hypothyroidism/myxoedema (self-reported)	0.1	0.3	0.9	0.4	0.9	0.4	-0.2	-0.1	0.1	-0.8	-0.5
Medication: Amlodipine	0.3	0.4	1.8	-0.5	0.6	-0.3	0.3	0.8	-0.2	0.5	1.3
Medication: Ventolin 100micrograms inhaler	0.5	0.6	2.0	-0.5	1.0	-1.0	-0.7	-0.2	-1.4	0.3	0.3
Birth weight	0.6	1.2	5.8	0.4	0.7	-0.0	0.3	1.6	0.4	-2.4	0.6
Chronic bronchitis/emphysema (mother)	0.6	0.7	2.7	0.2	-1.6	-0.3	-0.3	-0.1	-0.5	1.5	0.3
High blood pressure (siblings)	1.6	2.3	5.8	2.4	-1.5	1.1	0.6	0.0	0.7	2.4	-1.6
Forced vital capacity (FVC), Best measure	0.1	0.3	0.9	0.9	-0.2	0.3	0.4	0.7	0.5	-0.1	-0.5
Body fat percentage	0.4	1.6	4.1	-0.1	-0.2	-1.6	-2.0	0.7	-2.0	0.9	1.0
Leg fat percentage (right)	0.5	1.9	4.5	-0.3	-0.1	-2.1	-1.6	1.0	-2.0	1.4	1.2
Arm fat-free mass (right)	0.4	2.1	8.0	1.2	1.4	-0.6	1.6	-0.7	0.3	-2.8	1.5
Exposure to tobacco smoke outside home	1.1	1.5	4.2	-0.6	0.6	-1.5	-2.1	-0.8	-1.7	-0.2	1.1
Comparative body size at age 10	0.3	1.0	3.0	0.7	0.4	0.6	-1.0	-1.6	-0.4	1.7	-0.2
Number of full brothers	0.3	0.4	2.3	0.5	-0.0	-0.3	0.3	-0.4	-0.3	-1.5	-0.4
Worry too long after embarrassment	1.7	2.8	7.6	0.8	0.6	-1.8	-2.8	0.1	-2.7	-1.3	1.3
Seen a psychiatrist for nerves, anxiety, tension or depression	1.2	1.6	5.9	0.8	2.4	0.0	0.4	2.4	0.5	-0.5	-0.2
Wheeze or whistling in the chest in last year	1.1	2.0	4.3	0.3	1.3	-1.4	-2.1	0.6	-1.9	2.0	0.3
Number of children fathered	1.3	1.4	6.4	-1.1	-0.1	-1.3	-0.7	0.5	-1.1	2.5	0.1
Reason for reducing amount of alcohol drunk: Health precaution	2.0	2.3	7.1	-2.1	-0.6	-2.1	-0.5	-0.4	-1.5	-0.1	2.7
Age at first live birth	0.3	0.6	2.1	-1.1	0.0	-0.4	-0.0	1.5	-0.2	-1.1	0.3
Pulse wave peak to peak time	0.5	0.6	2.2	-0.2	1.5	-0.5	-0.0	0.8	-0.6	-0.8	0.8
Health satisfaction	1.1	1.4	4.3	-0.6	1.0	-1.0	-1.9	-0.4	-2.1	0.1	0.8
Shortness of breath walking on level ground	1.0	1.2	5.0	-0.0	0.9	-0.0	-2.2	-1.3	-1.5	0.3	-0.2
Qualifications: College or University degree	0.7	2.1	6.5	0.5	0.0	2.5	-0.0	-2.0	1.5	0.1	-1.9
Eye problems/disorders: None of the above	1.1	1.3	7.5	-0.7	2.7	-0.9	-0.1	-0.3	-0.6	0.1	1.0
Mouth/teeth dental problems: Loose teeth	0.8	1.0	4.5	1.0	-2.1	-0.3	-0.7	-0.8	-0.6	-0.5	0.6
Emphysema/chronic bronchitis	0.7	0.8	1.7	0.5	0.2	0.7	-1.0	-1.3	-0.2	0.8	-1.3
Medication for pain relief, constipation, heartburn	0.3	0.5	0.8	0.8	-0.8	0.8	0.5	-0.8	0.9	0.3	-0.5
Neck or shoulder pain in last month	0.6	0.8	2.4	-0.0	-0.8	-0.6	1.0	0.6	0.2	-1.6	1.3
Medication: Blood pressure	0.6	1.1	2.6	0.6	-0.2	-0.9	-1.0	-1.0	-1.5	-1.0	1.6
Angina (self-reported)	1.2	1.5	4.5	0.2	0.3	0.3	-1.4	-1.9	-0.4	2.1	-1.3
Migraine (self-reported)	0.5	0.6	1.3	0.6	-0.4	1.1	-0.2	-0.6	1.0	-0.6	-1.1
Medication: Ibuprofen	0.1	0.1	0.4	-0.0	0.3	0.1	0.3	-0.1	0.4	0.7	-0.7
Medication: Allopurinol	0.5	0.6	3.1	-0.7	-1.8	0.6	0.2	0.3	0.6	0.6	-0.6
Medication: Omeprazole	0.8	1.0	2.9	0.8	-0.2	1.3	1.7	0.2	1.4	-0.6	-0.7
Medication: Seretide 50 evohaler	0.8	0.9	2.4	1.1	0.7	0.6	0.1	-1.6	0.3	1.5	-0.7
Mean time to correctly identify matches	1.1	2.1	4.7	-1.5	-0.5	-2.2	-0.9	0.8	-2.0	0.1	2.1
Heart disease (mother)	0.4	0.5	2.7	-0.4	-0.8	-0.2	0.5	-0.4	-0.0	-1.6	0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.6	1.9	4.0	-1.0	0.8	-1.6	-1.8	0.3	-2.0	-0.8	1.7
Whole body fat mass	0.3	1.4	3.5	-0.1	0.1	-1.9	-1.5	0.4	-1.8	-0.0	1.4
Leg fat mass (right)	0.5	1.8	5.0	-0.3	0.1	-2.2	-1.5	0.6	-2.1	0.4	1.5
Arm predicted mass (right)	0.5	2.4	9.4	1.3	1.6	-0.3	1.7	-0.7	0.6	-3.1	1.4
Pulse rate, automated reading	0.6	1.9	9.8	-0.9	-0.4	-1.4	0.2	3.1	-0.5	1.5	0.3
Alcohol intake frequency.	0.5	1.2	3.4	-0.4	-0.5	-0.8	-1.8	0.9	-1.8	0.9	0.7
Comparative height size at age 10	0.2	1.0	4.2	0.2	2.1	-0.7	0.7	0.7	-0.2	0.2	1.5
Number of full sisters	1.4	1.7	5.6	-0.3	0.6	-1.7	0.9	1.5	-1.3	-0.1	2.4
Suffer from ‘nerves’	0.5	0.8	4.4	0.5	2.1	-0.8	-0.7	0.1	-0.6	0.5	-0.2
Overall health rating	0.6	1.2	2.2	-1.5	1.0	-1.1	-0.9	1.1	-1.4	0.8	0.6
Chest pain or discomfort	1.3	1.9	6.0	1.4	-0.4	1.9	0.8	-0.4	1.4	-0.4	-2.5
Had major operations	0.4	0.5	1.3	0.0	1.1	-0.7	-0.9	-0.6	-0.8	-0.1	0.5
Age at last live birth	0.8	1.2	4.2	-1.4	1.0	-0.8	0.2	2.0	-0.2	-1.1	0.7
Family relationship satisfaction	0.2	0.3	0.8	0.9	0.3	0.1	-0.1	0.1	-0.1	-0.7	0.7
Leg pain on walking	0.2	0.3	0.8	-0.8	0.1	0.1	-0.3	0.3	0.6	-0.5	-0.9
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	2.3	-0.4	0.1	-1.0	0.7	1.5	0.0	-0.8	0.5
Commuting to job workplace: Car/motor vehicle	1.0	1.1	2.3	-1.1	0.8	-1.5	-1.2	0.2	-1.5	-0.6	1.0
Illness, injury, bereavement, stress in last 2 years	0.7	0.8	3.5	-1.9	0.0	-0.9	-0.2	0.9	-0.5	0.9	0.6
Medication: Aspirin	0.4	0.5	2.4	-1.6	0.5	-0.9	-0.0	0.1	-0.7	0.2	0.5
Supplements: Vitamin C	2.2	2.6	12.3	0.3	-0.7	0.7	1.7	3.5	1.4	-1.4	0.4
Knee pain experienced in last month	1.7	2.7	7.3	-0.3	2.6	-2.1	0.6	1.1	-1.2	-0.4	2.7
Hypertension (Self-reported)	0.2	0.6	1.4	-0.1	-1.2	-0.1	-0.5	-1.1	-0.9	0.9	0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.8	0.9	3.7	0.6	-0.9	0.6	1.0	1.9	0.6	0.8	-0.0
Illnesses of father: Heart disease	0.5	0.7	2.3	-0.1	-1.5	-0.6	-0.1	0.2	-0.7	1.5	-0.0
Illnesses of siblings: Diabetes	0.6	0.7	1.8	0.8	-0.8	-0.4	-0.8	1.4	-0.7	1.1	0.2
Smoking status: Previous	0.4	0.6	2.1	0.3	-1.1	-0.6	0.9	0.6	0.0	1.4	0.5
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.8	3.7	0.0	0.6	0.2	0.5	-1.1	0.5	-1.9	-0.6
Whole body fat-free mass	0.3	1.5	5.6	0.8	1.3	-0.5	1.3	-0.2	0.2	-2.4	1.2
Leg fat-free mass (right)	0.2	1.0	3.9	0.4	0.9	-1.0	0.3	-0.2	-0.6	-2.0	1.4
Arm fat percentage (left)	0.4	1.5	4.6	0.1	0.2	-1.3	-2.1	0.8	-2.0	1.0	0.7
Average weekly red wine intake	2.5	3.6	5.6	2.4	-1.6	2.3	0.9	-1.9	2.3	-1.8	-1.5
Handedness (chirality/laterality): Left-handed	0.6	0.7	2.2	-0.3	-1.5	-0.9	0.7	1.0	-0.1	0.0	1.1
Mood swings	0.7	1.3	5.5	1.3	2.3	-0.6	-1.1	-0.2	-1.0	-0.3	0.1
Loneliness, isolation	0.2	0.2	0.7	0.7	-0.3	0.3	0.8	0.5	0.0	0.4	0.3
Long-standing illness, disability or infirmity	1.6	2.4	6.6	-0.9	1.4	-1.9	-1.9	0.4	-2.6	0.5	1.5
Ever had bowel cancer screening	0.9	1.0	3.2	1.8	-0.2	0.4	-1.3	-0.5	-0.9	-1.3	-0.1
Diabetes diagnosed by doctor	0.4	0.7	4.6	-0.3	2.1	-0.4	-0.4	-0.1	-0.6	0.3	0.4
Ever had stillbirth, spontaneous miscarriage or termination	2.9	3.2	5.5	-1.1	2.2	-2.3	-2.0	0.2	-2.3	-0.3	2.0
Friendships satisfaction	0.4	0.5	2.7	1.7	-0.5	0.6	-0.3	-0.5	0.1	-0.5	-0.2
Qualifications: nursing, teaching	0.3	0.5	1.6	0.4	-1.3	-0.0	-0.9	-0.8	-0.4	0.4	0.4
Commuting to job workplace: Walk	0.2	0.2	0.4	0.0	0.1	0.4	0.7	0.4	0.7	0.3	-0.3
Eye problems/disorders: Cataract	0.7	0.8	5.1	-0.2	-2.3	-0.3	0.5	0.3	0.4	-0.2	-0.6
Mouth/teeth dental problems: Mouth ulcers	0.9	1.4	3.3	1.1	-0.5	0.2	1.5	-1.8	0.5	-0.6	1.8
Medication for cholesterol	0.4	0.5	1.4	0.3	0.7	-0.0	-1.2	-1.0	-0.2	-1.1	0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.7	0.8	2.1	-0.5	1.2	0.5	-1.4	-0.8	-0.3	1.2	-0.6
Back pain experienced in last month	1.4	2.0	3.5	-1.4	0.8	-1.9	-1.5	1.4	-1.8	0.8	1.5
Mineral and other dietary supplements	0.7	0.9	3.1	-0.3	1.8	-0.4	-0.8	-0.3	-0.8	1.6	-0.4
Breast cancer (self-reported)	0.3	0.3	1.0	-0.7	-0.1	-0.9	1.0	0.1	0.4	0.4	0.3
Asthma (self-reported)	0.1	0.1	0.4	-0.2	0.4	-0.6	-0.2	-0.4	-0.7	0.2	0.1
Osteoporosis (self-reported)	0.2	0.3	1.5	-0.3	1.2	0.4	-0.5	-0.0	0.3	-0.1	-0.4
Osteoarthritis (self-reported)	0.5	0.7	1.3	-1.0	0.9	-0.7	-0.2	0.7	-0.9	1.1	0.9
Medication: Aspirin	0.2	0.3	2.0	-1.4	0.2	-0.4	0.2	0.2	-0.3	0.2	0.0
Medication: Gliclazide	1.4	1.6	3.7	-0.8	0.5	-1.3	-1.9	-0.8	-1.9	0.9	1.1
Illnesses of father: None of the above (group 1)	0.4	0.5	1.5	-1.0	-0.1	0.8	0.8	-0.2	1.2	0.4	-0.7
Smoking status: Current	1.3	2.1	5.1	-1.2	0.9	-2.3	-0.9	1.1	-1.7	0.9	1.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.5	1.5	1.0	-1.2	0.4	0.0	0.9	0.2	-0.2	-0.7
Whole body water mass	0.3	1.5	5.8	0.9	1.4	-0.5	1.3	-0.5	0.3	-2.4	1.2
Leg predicted mass (right)	0.2	1.1	4.2	0.4	1.0	-1.0	0.4	-0.1	-0.5	-2.1	1.4
Arm fat mass (left)	0.3	1.2	3.3	0.3	0.6	-1.4	-1.7	0.4	-1.8	0.0	0.9
Number of self-reported non-cancer illnesses	0.6	1.0	3.0	-1.4	-0.5	-0.5	-0.3	-1.7	-0.9	0.2	1.1
Average weekly champagne plus white wine intake	0.5	0.7	1.3	-1.0	0.5	0.5	0.8	-0.9	1.1	0.9	-0.6
Miserableness	0.2	0.4	1.2	1.1	0.6	0.2	-0.5	-0.9	-0.1	-0.6	-0.2
Guilty feelings	0.7	1.1	2.5	1.2	-1.0	-0.9	0.2	1.1	-0.9	-0.7	1.6
Wears glasses or contact lenses	1.1	1.2	6.0	0.5	0.4	0.1	-0.7	-1.7	-0.5	2.4	0.0
Ever taken oral contraceptive pill	0.2	0.3	0.6	0.8	0.7	0.2	-0.5	-0.4	-0.5	-0.5	-0.2
Hearing aid user	0.5	0.6	1.3	0.1	0.8	0.3	1.1	0.6	1.0	-0.2	-1.1
Mother’s age at death	1.4	1.8	4.9	2.2	-1.5	1.4	0.2	-1.3	1.2	-0.7	-1.1
Financial situation satisfaction	0.9	1.2	3.6	1.9	-1.4	1.3	-0.1	-0.7	0.3	0.7	-0.9
Tinnitus: Yes, now most or all of the time	1.4	1.6	4.0	-1.7	0.8	-2.0	-1.2	0.4	-1.6	-0.9	0.8
Commuting to job workplace: Public transport	0.6	0.7	2.9	0.8	0.9	0.7	-0.3	0.2	-0.1	1.7	-0.7
Eye problems/disorders: Glaucoma	1.2	1.5	3.5	1.5	-0.7	1.8	-0.3	-1.1	0.8	0.4	-1.9
Medication: Blood pressure	0.5	1.0	3.6	-0.6	-1.0	0.7	1.2	-0.7	0.7	1.9	0.3
Pain type(s) experienced in last month: Hip pain	0.7	0.8	2.5	0.0	0.8	-0.6	-1.6	-0.2	-1.2	1.3	-0.5
Supplements: Fish oil (including cod liver oil)	1.2	1.5	5.9	1.2	-2.4	0.9	0.8	0.2	1.2	-1.3	-0.0
High cholesterol (Self-reported)	1.0	1.8	5.2	-1.1	-1.8	0.5	-0.0	-2.3	0.6	0.9	-1.7
Medication: Bendroflumethiazide	0.2	0.3	1.6	0.2	-0.1	0.1	1.3	0.0	0.4	0.5	0.5
Medication: Paracetamol	0.9	1.4	2.7	-0.6	1.3	-1.4	-1.6	1.1	-1.6	0.3	0.6
Medication: Lisinopril	0.8	1.1	3.0	-0.8	-0.1	-1.6	-0.3	-0.5	-1.4	0.6	1.7
Medication: Atorvastatin	0.4	0.5	1.8	0.7	-1.4	0.2	-0.6	-0.8	0.2	-0.0	-0.7
Illnesses of father: High blood pressure	1.0	1.3	4.1	1.6	2.0	-0.1	-1.4	-0.2	-1.2	0.1	0.4
Alcohol drinker status: Never	0.6	0.7	2.3	-0.3	-0.3	-0.5	-1.2	0.9	-1.5	-0.1	0.7
Ever smoked	0.8	1.5	5.1	-1.1	-0.3	-1.7	-0.3	0.6	-1.1	2.3	0.8
Basal metabolic rate	0.2	1.2	4.4	0.7	1.1	-0.8	0.8	-0.2	-0.2	-2.1	1.4
Leg fat percentage (left)	0.7	2.4	6.0	-0.3	0.1	-2.5	-1.8	1.1	-2.3	0.9	1.6
Arm fat-free mass (left)	0.4	1.8	7.0	0.9	1.3	-0.8	1.3	-0.3	0.2	-2.6	1.6
Number of operations (self-reported)	0.5	0.7	1.8	0.6	1.4	0.4	0.6	-1.3	0.4	-1.1	-0.1
Average weekly beer plus cider intake	1.0	1.4	8.2	0.2	0.2	-0.8	0.9	2.9	-0.2	-0.1	1.4
Irritability	0.4	0.7	1.7	1.1	-1.3	-0.2	-1.2	-0.3	-0.3	-0.7	-0.3
Risk taking	0.2	0.2	1.0	0.6	0.0	-0.5	1.0	0.3	0.0	0.3	0.5
Ever had prostate specific antigen (PSA) test	0.2	0.2	0.7	0.4	-0.4	-0.2	-0.3	0.2	-0.3	-0.8	0.5
Fractured/broken bones in last 5 years	0.7	0.9	4.7	0.3	-0.4	-1.0	0.6	0.7	-0.4	0.7	2.2
Age started oral contraceptive pill	1.5	1.9	6.7	-0.6	-0.7	0.4	2.1	2.6	1.4	0.9	0.4
Diastolic blood pressure, automated reading	0.4	1.1	2.2	-0.9	-1.4	-0.7	-1.5	-1.3	-1.1	0.9	0.0
Ever depressed for a whole week	0.4	0.5	1.9	1.4	0.1	0.4	-1.3	-0.4	-0.7	0.0	-0.3
Unable to work because of sickness or disability	1.8	2.3	5.7	-1.4	-0.1	-2.4	0.1	1.9	-1.7	0.3	2.0
Commuting to job workplace: Cycle	0.5	0.6	2.2	1.3	-0.1	0.6	0.2	-0.5	0.3	-1.5	0.5
Myopia	1.4	2.0	4.9	-0.8	1.1	-1.0	-1.9	-2.2	-1.9	0.7	0.9
Vascular/heart problems diagnosed by doctor	0.2	0.5	1.5	0.1	0.7	0.7	0.5	0.5	1.2	0.1	-1.1
Cholesterol lowering medication	1.2	1.8	5.9	-1.2	-1.2	-0.5	-1.8	-0.0	-1.0	2.4	-1.2
Medication: Omeprazole (e.g. Zanprol)	0.7	0.9	1.7	0.7	-0.4	1.2	1.2	-0.1	1.0	-1.3	-0.8
Pain experienced in last month	0.7	1.2	3.3	0.7	-0.3	1.8	0.1	-0.7	1.3	0.7	-1.8
Supplements: Calcium	0.4	0.4	1.3	-0.4	0.4	0.1	-1.2	0.6	-0.4	-0.8	0.6
Basal cell carcinoma (self-reported)	1.5	1.7	8.0	1.4	2.8	0.9	0.4	-1.3	0.7	-0.7	-0.5
Heart attack/myocardial infarction (self-reported)	0.5	0.6	1.5	1.2	0.6	1.1	0.0	-0.1	0.9	-0.8	-0.6
Deep venous thrombosis (DVT) (self-reported)	1.2	1.5	3.2	0.8	-1.8	0.7	1.7	0.2	1.8	-0.1	-1.4
Heart disease (siblings)	1.0	1.3	3.6	0.0	-0.3	-1.6	-0.9	0.2	-1.9	0.9	1.4
Alcohol drinker status: Previous	0.3	0.3	1.1	-0.2	-1.0	-0.1	-0.5	1.0	-0.0	0.4	-0.2
Pack years of smoking	0.3	0.5	1.9	0.6	0.9	0.5	-0.6	-0.0	-0.5	1.4	-0.3
Impedance of whole body	0.1	0.6	1.3	0.0	-1.0	1.1	-0.2	-0.3	0.9	1.1	-0.9
Leg fat mass (left)	0.5	2.1	5.5	-0.2	0.3	-2.4	-1.6	0.7	-2.2	0.2	1.7
Arm predicted mass (left)	0.4	2.0	7.1	1.0	1.7	-0.6	1.5	-0.5	0.4	-2.7	1.4