Hub : Genes

DHCR24

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0580 0.0250 9.9e-03 0.002 0.002 0.008 0.008 0.000 1.5e-01 1.5e-01 3.0e-02 3.4e-02 2.8e-01
2 GTEx Brain Hypothalamus 0.4420 0.1230 2.9e-03 -0.013 NA 0.017 NA -0.006 9.4e-01 NA 1.3e-01 NA 4.7e-01
3 GTEx Cells Transformed fibroblasts 0.1200 0.0410 1.2e-03 0.064 NA 0.103 NA 0.103 1.5e-05 NA 3.8e-08 NA 3.8e-08
4 GTEx Esophagus Mucosa 0.1380 0.0500 2.9e-03 0.072 NA 0.023 NA 0.051 1.4e-05 NA 1.0e-02 NA 2.3e-04
5 GTEx Small Intestine Terminal Ileum 0.3750 0.1450 9.3e-03 0.019 NA -0.013 NA -0.012 1.2e-01 NA 9.3e-01 NA 7.6e-01
6 YFS Blood 0.0572 0.0128 4.3e-14 0.061 0.050 0.054 0.053 0.057 2.4e-19 6.8e-16 4.5e-17 8.9e-17 6.5e-18
7 TCGA Breast Invasive Carcinoma 0.0267 0.0140 1.6e-03 0.019 0.015 0.021 NA 0.019 5.7e-05 3.7e-04 3.5e-05 NA 8.2e-05
8 TCGA Lung Adenocarcinoma 0.0523 0.0278 8.8e-04 0.015 0.024 0.037 NA 0.020 6.9e-03 7.9e-04 3.4e-05 NA 1.8e-03

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.8 1.2 2.4 -0.2 1.5 -0.7 0.9 -1.0 -0.2 1.5 1.5
Bipolar Disorder or Schizophrenia 0.6 1.4 5.3 0.7 2.3 -0.0 -1.3 -0.3 -1.2 1.4 0.3
Depressed Affect (Nagel 2018) 0.2 0.4 2.2 1.5 0.5 0.3 -0.3 -0.4 0.1 -0.3 -0.5
Depression (Nagel 2018) 0.9 1.3 5.5 1.7 2.3 0.3 0.9 0.8 0.5 -0.5 0.0
Intelligence (Savage-Jansen 2018) 0.1 0.3 0.8 0.9 0.5 0.3 -0.6 0.4 -0.3 0.9 0.4
Neuroticism (Nagel 2018) 0.5 1.1 3.5 1.9 1.2 0.1 -1.6 0.4 -0.8 -0.6 -0.6
Schizophrenia (2018) 0.8 1.7 5.9 1.2 1.8 0.6 -2.4 0.4 -1.3 0.5 -0.6
Schizophrenia vs Biploar Disorder 0.3 0.4 0.9 -0.5 0.2 1.0 0.6 0.8 0.8 -0.4 -0.7
Worry (Nagel 2018) 0.7 1.5 5.3 1.6 2.3 0.2 -1.3 0.4 -0.5 -0.6 -1.2
Alzheimer’s Disease (in mother) 0.4 0.5 1.6 1.1 -0.6 0.4 -0.2 -0.2 0.4 0.4 -1.3
Alzheimer’s Disease (in father) 0.3 0.4 1.6 1.3 -0.5 0.2 -0.3 -0.4 0.3 -0.8 -0.1
Alzheimer’s Disease (including proxy) 0.5 0.7 1.8 1.3 0.2 0.6 -1.1 0.3 0.2 0.7 -1.1
Crohns Disease (2017) 1.7 3.7 7.6 -2.0 -1.9 -2.5 -2.0 1.0 -2.8 1.4 1.1
Irritable Bowel Disease (IBD) 1.5 3.5 8.5 -2.5 -1.5 -2.9 -1.5 -0.1 -2.4 0.7 1.5
Ulcerative Colitis (UC) 0.9 1.6 4.6 -2.0 -0.8 -2.1 -0.6 -0.8 -1.2 -0.3 1.1
Major Depression (MDD) 0.9 1.1 4.3 2.1 1.8 0.6 -0.3 -0.1 0.3 -0.4 0.3
Reaction Time 0.4 0.8 1.5 -0.3 -0.2 -1.2 -0.5 0.9 -1.2 -1.1 0.9
Verbal and Numeric Reasoning (VNR) 0.3 0.8 1.9 1.2 0.9 1.1 -0.6 -1.4 -0.3 0.3 -0.5
Breast Cancer 0.8 1.9 5.2 -0.8 -0.7 -1.1 -2.3 1.0 -1.7 1.9 -0.2
Ovarian Cancer 1.2 1.5 7.2 -0.3 0.1 0.2 1.9 2.7 0.9 -0.6 0.1
Prostate Cancer 0.2 0.3 0.6 0.5 0.3 0.8 0.7 -0.7 0.7 -0.1 -0.4
Age at First Birth 1.2 1.8 7.3 -0.2 2.7 -0.8 -0.5 -1.2 -1.2 -0.1 1.8
Bipolar Disorder (2011) 1.0 0.9 2.1 -1.1 -0.7 -1.3 0.5 -0.9 -0.4 0.9 1.5
Body Mass Index (BMI) (2010) 1.4 2.0 7.6 -1.0 2.8 -1.0 -1.6 1.1 -1.2 -1.0 -0.0
Coronary Artery Disease (CAD) 0.3 0.3 0.9 -0.9 0.6 -0.7 0.1 -0.2 -0.9 0.4 -0.0
Crohns Disease (2012) 0.9 1.5 3.3 -1.0 -0.8 -1.7 -0.6 1.8 -1.2 1.3 0.7
Mean Putamen Volume 1.4 1.6 4.8 2.1 -1.1 1.3 -0.1 -2.2 1.0 -0.1 -0.1
Fasting Glucose 0.8 0.9 2.7 0.8 -0.7 1.2 -0.8 -1.0 0.1 0.7 -1.7
HbA1C 0.4 0.4 1.2 -0.8 0.2 -0.4 -0.5 -0.3 -0.5 -1.1 0.8
HDL Cholesterol 1.0 1.6 2.7 1.3 1.2 1.6 1.0 -0.5 1.4 1.2 -1.5
LDL Cholesterol 1.3 2.1 5.8 -0.8 -2.4 -1.0 -1.4 -2.4 -1.3 -0.1 0.2
Lupus 1.5 2.3 4.2 2.1 2.1 1.9 0.3 -1.2 1.0 -1.8 -0.5
Neuroticism (2016) 1.0 1.4 4.8 2.2 -0.7 0.9 1.0 -0.6 0.8 -1.5 -1.1
Primary Biliary Cirrhosis 0.7 1.0 2.5 0.3 1.2 1.3 0.7 1.6 1.0 -0.2 -1.1
Rheumatoid Arthritis 0.3 0.4 1.3 -0.2 -0.6 1.1 -0.3 0.3 0.6 0.6 -0.7
Schizophrenia (2014) 0.3 0.7 2.0 1.1 1.2 0.4 -1.4 -0.1 -0.8 0.6 -0.3
Triglycerides 0.5 0.9 4.1 0.1 -1.2 -0.3 -0.3 -0.9 -0.7 -2.0 0.2
Type 2 Diabetes (T2D) (2012) 0.4 0.4 1.1 -1.0 0.0 -1.1 -0.3 0.3 -0.3 -0.3 0.9
Ulcerative Colitis 0.9 1.3 3.6 -1.9 0.6 -1.9 0.7 0.5 -0.2 -0.4 1.6
Blood Eosinophil Count 0.2 1.6 4.1 2.0 1.9 -0.3 -1.1 -1.7 -0.7 0.8 0.1
Blood Platelet Count 0.1 1.7 5.1 0.9 2.2 0.1 -2.2 0.0 -1.4 0.9 0.5
Blood Red Count 0.1 0.7 1.9 0.1 1.4 0.1 1.0 1.2 0.8 -0.3 0.5
Blood White Count 0.3 1.9 5.5 -0.3 1.6 -1.5 -2.4 0.8 -1.8 0.7 0.5
Heel T-Score 0.7 5.7 22.9 0.6 -4.8 2.0 2.1 -2.5 2.1 1.2 -1.4
BMI 0.2 0.9 1.8 0.3 0.1 -1.3 -0.5 0.6 -1.4 -1.1 1.3
Height 0.5 10.6 28.4 2.7 -0.2 3.0 5.3 -0.6 4.8 -4.0 -0.6
Waist Hip Ratio (WHR) 0.2 0.8 1.6 0.3 1.0 1.3 -0.9 -0.1 0.7 -1.0 -1.3
Systolic Blood Pressure 0.2 1.2 4.6 -1.5 -0.7 0.5 -0.6 -2.1 0.3 -0.9 -0.6
Smoking Status 0.8 1.9 4.4 -0.8 -0.6 -1.8 0.1 1.7 -0.8 2.1 1.8
Allergy or Eczema 0.1 0.2 1.1 -0.3 -0.6 -0.2 0.2 0.4 0.3 1.1 0.2
Cardiovascular Disease 0.6 2.0 9.5 0.4 -2.3 0.3 -0.5 -3.1 -0.6 -0.5 0.4
Hypothyroidism (self reported) 0.1 0.3 1.0 0.5 1.0 0.5 0.2 0.5 0.4 -0.5 -0.4
Respiratory disease 0.2 0.4 1.0 0.0 0.7 -0.5 -0.9 -0.2 -1.0 0.7 -0.3
Type 2 Diabetes (T2D) (2018) 0.5 0.9 2.7 -0.6 1.6 -1.1 -0.3 -0.2 -1.0 0.3 1.4
Lung FEV1/FVC ratio 0.1 0.5 2.4 -0.3 -0.5 -0.7 0.6 -0.8 -0.1 -1.6 0.1
Lung FVC 0.1 0.5 2.0 0.4 -1.4 0.0 -0.1 1.0 -0.1 0.8 0.3
Neuroticism 0.5 1.2 3.5 1.9 1.2 -0.4 -1.4 0.4 -0.8 -1.4 0.1
Chronotype (morning person) 0.2 0.4 0.9 -0.4 -0.9 0.0 -1.0 0.8 -0.6 -0.6 -0.2
Hair Pigment 0.0 1.1 3.4 0.3 -0.1 0.8 1.8 -1.1 1.5 -0.9 0.7
Tanning 0.0 0.5 1.4 -1.1 -0.2 -0.8 1.2 0.2 0.2 -0.5 0.8
Hand grip strength (left) 0.1 0.4 0.9 -0.2 -0.1 0.3 0.6 -0.9 0.8 -1.0 -0.4
Number of treatments/medications taken 0.3 0.6 1.8 -1.3 0.9 -1.0 0.2 0.5 -0.6 0.5 0.6
Average weekly spirits intake 1.1 1.4 5.6 -2.4 0.9 -1.6 0.4 -0.8 -0.4 0.7 0.8
Sensitivity / hurt feelings 1.0 1.6 3.8 -0.1 1.2 -1.2 -1.9 1.7 -1.8 -0.2 0.7
Frequency of depressed mood in last 2 weeks 1.4 1.9 5.9 1.1 2.4 -0.5 0.9 2.4 0.0 -1.2 0.4
Hearing difficulty/problems: Yes 0.3 0.5 1.5 0.5 0.2 -1.2 -0.4 0.4 -0.8 0.6 0.9
Relative age of first facial hair 1.3 2.8 5.1 -0.8 -0.5 -2.3 -1.9 0.3 -2.0 2.1 1.9
Other serious medical condition/disability diagnosed by doctor 3.4 4.4 8.5 -1.1 2.9 -2.8 -1.1 1.9 -2.5 -1.6 2.0
Ever used hormone-replacement therapy (HRT) 0.6 0.7 3.2 0.5 0.4 0.7 0.5 -1.0 0.2 0.5 -1.8
Ever had hysterectomy (womb removed) 0.8 0.9 4.4 1.1 -0.1 0.4 0.8 -2.1 0.4 -0.3 -0.6
Systolic blood pressure, automated reading 0.6 1.8 5.8 -2.4 -1.8 -0.7 -1.4 -1.0 -0.9 0.9 -0.3
Eye problems/disorders: Diabetes related eye disease 0.5 0.6 1.3 -0.4 0.1 -0.8 -0.9 0.2 -1.1 1.1 0.7
Angina 1.1 1.4 3.4 0.2 -0.2 0.2 -1.6 -1.8 -0.6 1.8 -1.3
Medication for hormone replacement therapy 0.3 0.4 1.4 0.1 0.4 -0.9 0.2 1.2 -0.6 -0.0 -0.2
Vitamin and mineral supplements 1.1 1.6 5.6 0.2 -0.3 -0.7 -1.8 -2.4 -1.2 1.3 -0.2
Supplements: Zinc 0.4 0.5 1.3 0.2 -1.1 1.0 -0.2 -0.4 0.5 -1.0 -0.4
Medication: Co-codamol 1.4 1.6 2.9 1.2 0.5 1.6 0.7 0.7 1.4 1.6 -1.7
Medication: Metformin 1.6 2.3 4.3 -0.9 1.5 -2.0 -1.4 -0.7 -2.1 1.3 1.8
Diabetes (father) 0.4 0.5 1.8 -0.3 -0.0 -0.6 -0.8 -0.1 -0.7 -1.4 0.7
Diabetes (mother) 1.2 1.5 9.5 -0.2 0.0 0.2 -0.6 1.1 -0.3 3.1 -0.8
Severe depression (siblings) 0.7 0.8 2.6 0.6 0.6 -1.2 -0.7 0.2 -1.6 1.0 0.7
Pack years adult smoking proportion 0.2 0.3 1.6 0.5 0.4 0.4 -0.5 0.1 -0.5 1.3 -0.0
Impedance of leg (right) 0.1 0.4 1.4 0.3 -0.5 0.7 0.6 -0.1 1.2 0.7 -0.7
Leg fat-free mass (left) 0.1 0.7 2.5 0.3 0.6 -1.0 0.2 -0.2 -0.6 -1.6 1.2
Trunk fat percentage 0.3 1.3 4.0 0.1 -0.6 -1.2 -2.0 0.4 -1.8 0.8 0.6
Hand grip strength (right) 0.1 0.2 1.5 -0.3 0.0 -0.3 -0.1 -1.2 0.1 0.2 0.4
Townsend deprivation index at recruitment 0.6 0.9 2.3 -1.1 0.1 -1.0 1.1 1.5 -0.3 -1.0 0.7
Current tobacco smoking 1.2 2.0 4.6 -1.0 1.4 -2.1 -0.9 1.1 -1.6 1.1 1.7
Average weekly fortified wine intake 0.6 0.7 3.5 0.2 0.1 1.0 0.2 -0.2 0.8 0.4 -1.9
Maternal smoking around birth 0.5 0.7 2.7 1.6 0.3 1.0 -0.2 -1.1 -0.1 0.2 -0.7
Fed-up feelings 0.2 0.3 0.7 0.8 -0.1 -0.8 0.2 0.5 -0.4 -0.8 0.4
Frequency of unenthusiasm / disinterest in last 2 weeks 0.7 1.0 6.0 0.4 2.5 -0.7 0.2 0.6 -0.5 0.6 0.4
Relative age voice broke 0.4 0.6 2.8 1.7 -0.7 0.5 -0.1 -0.7 0.5 0.1 -0.1
Taking other prescription medications 0.3 0.5 1.2 -1.1 0.6 -0.8 0.3 0.9 -0.6 -0.0 0.6
Age when periods started (menarche) 0.4 1.0 2.2 -0.8 -1.5 -0.6 1.4 -1.1 0.6 -1.2 0.6
Bilateral oophorectomy (both ovaries removed) 0.3 0.3 1.9 -0.1 -0.7 -0.2 0.1 -1.4 -0.5 0.1 -0.2
Heel bone mineral density (BMD) T-score, automated (left) 1.4 3.2 12.3 -2.4 -3.5 -1.4 -0.1 0.7 -1.1 1.3 1.4
Tinnitus: Yes, but not now, but have in the past 0.3 0.3 0.7 0.7 0.1 0.1 0.7 0.9 0.3 -0.6 0.1
Qualifications: CSEs or equivalent 1.3 1.8 3.8 -0.4 0.8 -1.4 -1.9 -1.5 -2.0 -0.5 1.3
Serious illness, injury or assault to yourself 2.4 2.9 9.3 -1.3 1.5 -1.3 1.7 3.1 -0.0 -1.3 1.8
High blood pressure 0.3 1.0 2.8 -0.5 -0.9 -1.0 -0.8 -0.3 -1.7 0.7 1.3
Hayfever, allergic rhinitis or eczema 0.2 0.3 1.2 -1.1 -0.2 -0.3 0.6 0.5 0.5 -0.0 0.7
Multivitamins +/- minerals 0.4 0.5 2.0 0.2 0.3 0.1 1.4 1.3 0.2 -0.5 0.4
Stomach or abdominal pain in last month 0.7 0.8 3.4 0.9 1.9 -0.3 -0.5 0.9 -0.9 0.2 0.6
Supplements: Glucosamine 0.4 0.6 2.5 0.3 -0.9 0.2 1.6 -0.4 1.0 -0.2 0.2
Diverticular disease/diverticulitis (self-reported) 2.6 3.1 6.8 -1.1 0.2 -1.5 -2.6 1.4 -2.5 2.4 -0.1
Medication: Atenolol 0.2 0.3 1.1 0.1 -0.8 0.3 -0.3 -0.1 -0.1 0.4 -1.1
Medication: Levothyroxine sodium 0.2 0.4 1.7 -0.0 1.0 0.5 0.2 0.1 0.2 0.4 -1.3
Sitting height 0.6 4.5 15.0 0.5 1.6 0.4 3.9 -0.3 2.4 -3.4 0.9
Chronic bronchitis/emphysema (father) 0.5 0.6 3.4 1.8 0.1 0.5 0.9 -0.1 0.6 0.1 0.4
High blood pressure (mother) 0.7 0.9 3.2 -1.1 0.3 0.5 0.8 -0.6 0.7 1.8 -1.0
Body mass index (BMI) 0.4 1.9 5.6 -0.1 -0.3 -1.8 -2.1 0.3 -2.4 0.5 1.1
Impedance of leg (left) 0.0 0.2 0.8 0.3 -0.0 0.4 0.4 0.1 0.9 -0.0 -0.1
Leg predicted mass (left) 0.1 0.7 2.5 0.4 0.7 -0.9 0.2 -0.3 -0.5 -1.6 1.1
Trunk fat mass 0.2 0.9 2.2 0.3 -0.3 -1.3 -1.3 0.4 -1.5 0.1 1.1
Waist circumference 0.2 0.6 1.7 0.4 -0.3 -1.0 -1.2 -0.0 -1.3 0.4 0.5
Number of incorrect matches in round 0.2 0.3 0.9 0.9 -0.2 0.3 -0.4 0.7 -0.3 -0.9 -0.0
Past tobacco smoking 0.7 1.3 4.8 0.5 0.8 1.5 -0.1 -0.6 0.9 -2.2 -1.0
Alcohol usually taken with meals 1.1 1.7 4.4 1.1 -0.8 1.6 1.9 -0.2 2.1 -0.5 -1.1
Nervous feelings 0.3 0.5 2.1 0.1 0.5 -0.5 -0.4 0.6 -0.8 1.4 0.3
Frequency of tenseness / restlessness in last 2 weeks 0.5 0.8 2.1 1.0 0.8 -0.6 1.3 0.8 0.5 -1.4 0.2
Hearing difficulty/problems with background noise 0.4 0.6 2.1 -0.1 -0.1 0.1 -0.7 -1.5 -0.4 1.1 -0.8
Hair/balding pattern: Pattern 2 0.6 0.7 3.2 0.7 -1.8 0.9 0.4 -0.3 0.8 -0.2 -0.6
Had menopause 0.6 0.7 1.7 0.3 -0.1 1.3 1.2 -0.8 1.3 0.2 -0.5
Had other major operations 0.7 0.9 2.7 -1.1 1.6 -1.0 0.2 0.1 -0.8 -0.7 1.2
Forced vital capacity (FVC) 0.1 0.3 0.7 0.8 -0.5 -0.2 0.7 0.3 0.3 -0.5 0.6
Heel bone mineral density (BMD) T-score, automated (right) 1.2 2.7 8.9 -1.6 -3.0 -1.4 -0.9 0.9 -1.5 1.8 0.9
Ever unenthusiastic/disinterested for a whole week 1.3 1.6 5.6 0.8 2.4 -0.9 -0.4 0.7 -0.9 -1.7 0.9
Qualifications: None of the above 0.4 0.9 2.8 -1.1 -0.7 -1.7 0.2 0.7 -0.9 0.6 1.2
Financial difficulties in last 2 years 1.0 1.3 4.7 1.1 1.8 -0.2 0.5 0.5 -0.0 -2.2 1.0
Mouth/teeth dental problems 0.2 0.4 0.9 -0.0 0.5 1.0 -0.7 0.4 -0.1 0.6 -0.9
Heart attack 0.6 0.7 1.4 1.2 0.8 1.1 -0.2 -0.1 0.9 -1.0 -0.8
Allergy 0.1 0.3 1.0 0.5 -0.1 1.0 -0.4 -0.3 0.1 -0.0 -1.0
Pain all over the body in last month 0.5 0.6 2.3 -1.0 1.0 -0.1 0.1 -0.1 -0.5 -1.5 0.4
Diabetes (self-reported) 0.3 0.5 3.0 0.0 1.7 0.3 -0.5 -0.6 -0.4 0.5 0.1
Hayfever/allergic rhinitis (self-reported) 1.9 2.5 6.9 1.6 0.5 2.6 0.5 -0.5 1.9 -0.2 -2.4
Medication: Ramipril 0.4 0.5 2.8 -0.5 1.7 0.1 -0.7 -0.6 -0.4 -0.2 0.3
Medication: Simvastatin 0.6 0.8 2.5 -0.2 -1.4 -0.8 -0.4 -1.6 -0.7 0.8 -0.3
Fluid intelligence score 0.2 0.5 1.1 1.0 0.9 1.0 0.3 -0.3 0.4 -0.2 -0.5
Illnesses of siblings 1.5 2.2 9.4 -1.4 1.2 0.7 1.0 -1.0 1.4 -3.1 -0.1
Neuroticism score 0.5 1.0 2.3 0.8 0.8 -1.2 -1.5 0.8 -1.5 -0.2 0.3
Weight 0.2 0.9 2.2 0.5 0.3 -1.5 -0.6 -0.1 -1.3 -0.6 1.5
Impedance of arm (right) 0.2 0.9 3.1 -0.4 -1.4 0.9 -0.3 -0.4 0.6 1.8 -0.8
Arm fat percentage (right) 0.5 2.0 5.2 -0.3 -0.1 -1.6 -2.3 0.8 -2.2 1.2 0.9
Trunk fat-free mass 0.3 1.9 6.2 1.0 1.4 -0.3 1.9 -0.2 0.8 -2.5 1.2
Hip circumference 0.1 0.5 1.1 0.9 -0.2 -0.9 -0.8 -0.1 -1.1 -0.1 0.9
Time employed in main current job 0.4 0.5 1.2 0.6 1.1 -0.7 -0.2 0.2 -0.2 -1.0 0.9
Alcohol intake versus 10 years previously 0.9 1.4 6.9 -1.4 0.3 -0.7 -0.5 2.6 -1.1 0.1 0.6
Father’s age at death 0.5 0.6 1.5 -0.7 0.6 1.2 0.5 -0.1 1.0 0.1 -1.2
Worrier / anxious feelings 0.3 0.6 1.1 1.1 0.0 -0.6 -1.0 1.1 -1.0 -0.7 -0.1
Frequency of tiredness / lethargy in last 2 weeks 0.4 0.6 3.0 -0.4 1.7 -0.6 -0.7 0.3 -0.7 -0.4 -0.1
Falls in the last year 0.4 0.5 2.9 -0.3 -1.7 -0.2 0.2 0.8 -0.0 0.5 0.2
Hair/balding pattern: Pattern 3 0.2 0.3 1.1 0.3 -0.7 0.3 -0.1 -0.4 0.5 -0.2 -1.1
Number of live births 0.6 0.9 2.5 1.2 1.6 -0.4 -0.3 -0.4 -0.6 -0.7 1.4
Forced expiratory volume in 1-second (FEV1) 0.1 0.2 0.6 0.1 -0.5 -0.7 0.3 0.3 -0.1 -0.4 0.5
Pulse rate 0.9 1.5 6.7 -0.3 2.6 -0.4 0.4 2.0 0.2 -0.2 0.8
Happiness 1.6 2.0 8.1 0.6 0.5 0.4 2.8 0.6 1.6 -2.0 0.0
Noisy workplace 0.4 0.5 1.5 0.2 0.5 -0.3 -1.0 -1.2 -0.6 0.9 0.1
Qualifications: A levels/AS levels or equivalent 1.4 3.1 8.1 2.6 1.2 2.9 0.2 -0.4 1.8 -1.4 -1.8
Serious illness, injury or assault of a close relative in last 2 years 0.8 1.0 1.7 0.2 -1.1 -1.1 -1.1 -1.2 -1.3 0.4 0.8
Mouth/teeth dental problems: Dentures 0.3 0.6 1.9 -1.1 0.1 -0.7 -0.6 0.6 -0.3 1.4 -0.4
Asthma 0.1 0.2 0.3 0.4 0.4 -0.1 -0.4 -0.5 -0.5 0.2 -0.3
Medication: Ibuprofen (e.g. Nurofen) 0.1 0.2 0.5 -0.4 0.4 -0.7 0.4 -0.0 -0.4 0.4 0.4
Medication: Cholesterol lowering 1.2 1.8 7.4 0.9 -1.6 0.3 0.4 -2.7 0.6 -1.8 -0.1
Depression (self-reported) 0.5 0.6 1.8 1.3 0.7 0.9 -0.3 -0.2 -0.0 1.2 -0.4
Medication: Lansoprazole 0.4 0.5 1.8 0.0 -0.2 0.5 -1.0 -1.4 -0.4 -0.5 0.5
Prospective memory result 0.7 0.8 3.1 -0.9 -0.2 -0.6 0.8 1.8 0.6 0.4 1.0
Lung cancer (father) 0.8 0.9 4.5 2.1 -0.3 1.1 0.1 -0.8 0.8 0.1 -0.4
Illnesses of mother 1.3 1.7 3.6 -0.5 1.1 -1.2 0.0 1.9 -0.8 -1.8 1.7
Forced expiratory volume in 1-second (FEV1), Best measure 0.1 0.4 1.2 1.0 -0.2 0.0 0.4 1.1 0.4 -0.6 -0.5
Pulse wave Arterial Stiffness index 0.4 0.5 1.7 0.3 -1.3 0.4 0.4 -0.6 0.6 0.7 -0.5
Impedance of arm (left) 0.3 1.3 3.2 0.2 -1.0 1.6 -0.6 -0.6 0.9 1.8 -1.4
Arm fat mass (right) 0.3 1.3 3.9 0.1 0.2 -1.6 -1.8 0.2 -2.0 0.2 1.0
Trunk predicted mass 0.4 2.0 6.6 1.1 1.5 -0.3 2.0 -0.2 0.8 -2.6 1.3
Standing height 0.3 2.7 7.2 1.1 1.2 0.6 2.7 -1.3 2.1 -2.3 0.6
Length of working week for main job 0.7 0.8 3.7 -0.2 1.9 -0.7 0.3 -0.4 -0.5 -1.2 0.5
Exposure to tobacco smoke at home 0.9 1.0 2.4 -0.7 0.8 -1.1 -1.2 -0.8 -1.5 -0.5 1.0
Breastfed as a baby 0.2 0.2 0.5 0.3 -0.6 -0.2 0.7 -0.0 0.3 -0.7 -0.5
Tense / ‘highly strung’ 0.6 1.1 2.2 1.2 1.4 0.1 1.0 0.7 0.9 -1.5 -0.6
Seen doctor (GP) for nerves, anxiety, tension or depression 0.2 0.3 1.6 1.3 0.7 0.5 -0.2 0.2 -0.3 0.3 -0.0
Hair/balding pattern: Pattern 4 0.7 1.7 5.0 1.2 1.1 0.6 2.2 0.4 0.8 -1.7 1.2
Birth weight of first child 0.4 0.7 2.2 -0.8 1.5 -0.5 0.1 -0.7 -0.3 -0.5 1.2
Peak expiratory flow (PEF) 0.6 1.3 3.7 -1.0 -0.2 -1.9 -0.6 0.2 -1.4 -1.3 1.3
Pulse wave reflection index 1.6 2.0 6.5 0.7 -2.5 1.0 1.7 -1.6 1.4 0.0 -0.6
Ever highly irritable/argumentative for 2 days 1.1 1.3 2.9 1.6 1.5 0.4 0.2 -1.7 0.3 -1.4 0.4
Loud music exposure frequency 2.0 2.1 5.8 -0.3 2.0 -1.3 -1.5 -0.5 -1.6 2.4 0.8
Qualifications: O levels/GCSEs or equivalent 1.1 1.7 3.4 1.8 1.3 1.9 -0.5 -0.9 1.1 -1.0 -1.3
Mouth/teeth dental problems: Bleeding gums 0.2 0.3 1.0 -0.2 -1.0 -0.9 0.2 -0.4 -0.3 -0.2 0.2
Blood clot in the leg (DVT) 1.1 1.4 3.5 0.8 -1.3 0.7 1.8 0.1 1.9 -0.3 -1.2
Medication: Paracetamol 1.0 1.7 3.7 -0.7 1.4 -1.3 -1.8 0.9 -1.9 0.0 1.1
Headache pain in last month 0.7 1.2 3.4 -0.7 1.9 -0.9 -1.5 1.2 -1.0 0.2 -0.0
Medication for cholesterol, blood pressure or diabetes 0.9 1.5 6.8 -1.1 0.8 0.2 0.4 2.6 0.7 1.4 -1.0
Glaucoma (self-reported) 0.3 0.4 1.0 0.9 -0.3 0.8 0.3 -1.0 0.3 0.1 -0.5
Gout (self-reported) 0.6 0.8 3.5 -0.2 -1.9 0.6 -0.8 0.4 0.2 1.0 -0.8
Hypothyroidism/myxoedema (self-reported) 0.1 0.3 0.9 0.4 0.9 0.4 -0.2 -0.1 0.1 -0.8 -0.5
Medication: Amlodipine 0.3 0.4 1.8 -0.5 0.6 -0.3 0.3 0.8 -0.2 0.5 1.3
Medication: Ventolin 100micrograms inhaler 0.5 0.6 2.0 -0.5 1.0 -1.0 -0.7 -0.2 -1.4 0.3 0.3
Birth weight 0.6 1.2 5.8 0.4 0.7 -0.0 0.3 1.6 0.4 -2.4 0.6
Chronic bronchitis/emphysema (mother) 0.6 0.7 2.7 0.2 -1.6 -0.3 -0.3 -0.1 -0.5 1.5 0.3
High blood pressure (siblings) 1.6 2.3 5.8 2.4 -1.5 1.1 0.6 0.0 0.7 2.4 -1.6
Forced vital capacity (FVC), Best measure 0.1 0.3 0.9 0.9 -0.2 0.3 0.4 0.7 0.5 -0.1 -0.5
Body fat percentage 0.4 1.6 4.1 -0.1 -0.2 -1.6 -2.0 0.7 -2.0 0.9 1.0
Leg fat percentage (right) 0.5 1.9 4.5 -0.3 -0.1 -2.1 -1.6 1.0 -2.0 1.4 1.2
Arm fat-free mass (right) 0.4 2.1 8.0 1.2 1.4 -0.6 1.6 -0.7 0.3 -2.8 1.5
Exposure to tobacco smoke outside home 1.1 1.5 4.2 -0.6 0.6 -1.5 -2.1 -0.8 -1.7 -0.2 1.1
Comparative body size at age 10 0.3 1.0 3.0 0.7 0.4 0.6 -1.0 -1.6 -0.4 1.7 -0.2
Number of full brothers 0.3 0.4 2.3 0.5 -0.0 -0.3 0.3 -0.4 -0.3 -1.5 -0.4
Worry too long after embarrassment 1.7 2.8 7.6 0.8 0.6 -1.8 -2.8 0.1 -2.7 -1.3 1.3
Seen a psychiatrist for nerves, anxiety, tension or depression 1.2 1.6 5.9 0.8 2.4 0.0 0.4 2.4 0.5 -0.5 -0.2
Wheeze or whistling in the chest in last year 1.1 2.0 4.3 0.3 1.3 -1.4 -2.1 0.6 -1.9 2.0 0.3
Number of children fathered 1.3 1.4 6.4 -1.1 -0.1 -1.3 -0.7 0.5 -1.1 2.5 0.1
Reason for reducing amount of alcohol drunk: Health precaution 2.0 2.3 7.1 -2.1 -0.6 -2.1 -0.5 -0.4 -1.5 -0.1 2.7
Age at first live birth 0.3 0.6 2.1 -1.1 0.0 -0.4 -0.0 1.5 -0.2 -1.1 0.3
Pulse wave peak to peak time 0.5 0.6 2.2 -0.2 1.5 -0.5 -0.0 0.8 -0.6 -0.8 0.8
Health satisfaction 1.1 1.4 4.3 -0.6 1.0 -1.0 -1.9 -0.4 -2.1 0.1 0.8
Shortness of breath walking on level ground 1.0 1.2 5.0 -0.0 0.9 -0.0 -2.2 -1.3 -1.5 0.3 -0.2
Qualifications: College or University degree 0.7 2.1 6.5 0.5 0.0 2.5 -0.0 -2.0 1.5 0.1 -1.9
Eye problems/disorders: None of the above 1.1 1.3 7.5 -0.7 2.7 -0.9 -0.1 -0.3 -0.6 0.1 1.0
Mouth/teeth dental problems: Loose teeth 0.8 1.0 4.5 1.0 -2.1 -0.3 -0.7 -0.8 -0.6 -0.5 0.6
Emphysema/chronic bronchitis 0.7 0.8 1.7 0.5 0.2 0.7 -1.0 -1.3 -0.2 0.8 -1.3
Medication for pain relief, constipation, heartburn 0.3 0.5 0.8 0.8 -0.8 0.8 0.5 -0.8 0.9 0.3 -0.5
Neck or shoulder pain in last month 0.6 0.8 2.4 -0.0 -0.8 -0.6 1.0 0.6 0.2 -1.6 1.3
Medication: Blood pressure 0.6 1.1 2.6 0.6 -0.2 -0.9 -1.0 -1.0 -1.5 -1.0 1.6
Angina (self-reported) 1.2 1.5 4.5 0.2 0.3 0.3 -1.4 -1.9 -0.4 2.1 -1.3
Migraine (self-reported) 0.5 0.6 1.3 0.6 -0.4 1.1 -0.2 -0.6 1.0 -0.6 -1.1
Medication: Ibuprofen 0.1 0.1 0.4 -0.0 0.3 0.1 0.3 -0.1 0.4 0.7 -0.7
Medication: Allopurinol 0.5 0.6 3.1 -0.7 -1.8 0.6 0.2 0.3 0.6 0.6 -0.6
Medication: Omeprazole 0.8 1.0 2.9 0.8 -0.2 1.3 1.7 0.2 1.4 -0.6 -0.7
Medication: Seretide 50 evohaler 0.8 0.9 2.4 1.1 0.7 0.6 0.1 -1.6 0.3 1.5 -0.7
Mean time to correctly identify matches 1.1 2.1 4.7 -1.5 -0.5 -2.2 -0.9 0.8 -2.0 0.1 2.1
Heart disease (mother) 0.4 0.5 2.7 -0.4 -0.8 -0.2 0.5 -0.4 -0.0 -1.6 0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.6 1.9 4.0 -1.0 0.8 -1.6 -1.8 0.3 -2.0 -0.8 1.7
Whole body fat mass 0.3 1.4 3.5 -0.1 0.1 -1.9 -1.5 0.4 -1.8 -0.0 1.4
Leg fat mass (right) 0.5 1.8 5.0 -0.3 0.1 -2.2 -1.5 0.6 -2.1 0.4 1.5
Arm predicted mass (right) 0.5 2.4 9.4 1.3 1.6 -0.3 1.7 -0.7 0.6 -3.1 1.4
Pulse rate, automated reading 0.6 1.9 9.8 -0.9 -0.4 -1.4 0.2 3.1 -0.5 1.5 0.3
Alcohol intake frequency. 0.5 1.2 3.4 -0.4 -0.5 -0.8 -1.8 0.9 -1.8 0.9 0.7
Comparative height size at age 10 0.2 1.0 4.2 0.2 2.1 -0.7 0.7 0.7 -0.2 0.2 1.5
Number of full sisters 1.4 1.7 5.6 -0.3 0.6 -1.7 0.9 1.5 -1.3 -0.1 2.4
Suffer from ‘nerves’ 0.5 0.8 4.4 0.5 2.1 -0.8 -0.7 0.1 -0.6 0.5 -0.2
Overall health rating 0.6 1.2 2.2 -1.5 1.0 -1.1 -0.9 1.1 -1.4 0.8 0.6
Chest pain or discomfort 1.3 1.9 6.0 1.4 -0.4 1.9 0.8 -0.4 1.4 -0.4 -2.5
Had major operations 0.4 0.5 1.3 0.0 1.1 -0.7 -0.9 -0.6 -0.8 -0.1 0.5
Age at last live birth 0.8 1.2 4.2 -1.4 1.0 -0.8 0.2 2.0 -0.2 -1.1 0.7
Family relationship satisfaction 0.2 0.3 0.8 0.9 0.3 0.1 -0.1 0.1 -0.1 -0.7 0.7
Leg pain on walking 0.2 0.3 0.8 -0.8 0.1 0.1 -0.3 0.3 0.6 -0.5 -0.9
Qualifications: NVQ or HND or HNC or equivalent 0.5 0.6 2.3 -0.4 0.1 -1.0 0.7 1.5 0.0 -0.8 0.5
Commuting to job workplace: Car/motor vehicle 1.0 1.1 2.3 -1.1 0.8 -1.5 -1.2 0.2 -1.5 -0.6 1.0
Illness, injury, bereavement, stress in last 2 years 0.7 0.8 3.5 -1.9 0.0 -0.9 -0.2 0.9 -0.5 0.9 0.6
Medication: Aspirin 0.4 0.5 2.4 -1.6 0.5 -0.9 -0.0 0.1 -0.7 0.2 0.5
Supplements: Vitamin C 2.2 2.6 12.3 0.3 -0.7 0.7 1.7 3.5 1.4 -1.4 0.4
Knee pain experienced in last month 1.7 2.7 7.3 -0.3 2.6 -2.1 0.6 1.1 -1.2 -0.4 2.7
Hypertension (Self-reported) 0.2 0.6 1.4 -0.1 -1.2 -0.1 -0.5 -1.1 -0.9 0.9 0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.8 0.9 3.7 0.6 -0.9 0.6 1.0 1.9 0.6 0.8 -0.0
Illnesses of father: Heart disease 0.5 0.7 2.3 -0.1 -1.5 -0.6 -0.1 0.2 -0.7 1.5 -0.0
Illnesses of siblings: Diabetes 0.6 0.7 1.8 0.8 -0.8 -0.4 -0.8 1.4 -0.7 1.1 0.2
Smoking status: Previous 0.4 0.6 2.1 0.3 -1.1 -0.6 0.9 0.6 0.0 1.4 0.5
Forced expiratory volume in 1-second (FEV1), predicted 0.4 0.8 3.7 0.0 0.6 0.2 0.5 -1.1 0.5 -1.9 -0.6
Whole body fat-free mass 0.3 1.5 5.6 0.8 1.3 -0.5 1.3 -0.2 0.2 -2.4 1.2
Leg fat-free mass (right) 0.2 1.0 3.9 0.4 0.9 -1.0 0.3 -0.2 -0.6 -2.0 1.4
Arm fat percentage (left) 0.4 1.5 4.6 0.1 0.2 -1.3 -2.1 0.8 -2.0 1.0 0.7
Average weekly red wine intake 2.5 3.6 5.6 2.4 -1.6 2.3 0.9 -1.9 2.3 -1.8 -1.5
Handedness (chirality/laterality): Left-handed 0.6 0.7 2.2 -0.3 -1.5 -0.9 0.7 1.0 -0.1 0.0 1.1
Mood swings 0.7 1.3 5.5 1.3 2.3 -0.6 -1.1 -0.2 -1.0 -0.3 0.1
Loneliness, isolation 0.2 0.2 0.7 0.7 -0.3 0.3 0.8 0.5 0.0 0.4 0.3
Long-standing illness, disability or infirmity 1.6 2.4 6.6 -0.9 1.4 -1.9 -1.9 0.4 -2.6 0.5 1.5
Ever had bowel cancer screening 0.9 1.0 3.2 1.8 -0.2 0.4 -1.3 -0.5 -0.9 -1.3 -0.1
Diabetes diagnosed by doctor 0.4 0.7 4.6 -0.3 2.1 -0.4 -0.4 -0.1 -0.6 0.3 0.4
Ever had stillbirth, spontaneous miscarriage or termination 2.9 3.2 5.5 -1.1 2.2 -2.3 -2.0 0.2 -2.3 -0.3 2.0
Friendships satisfaction 0.4 0.5 2.7 1.7 -0.5 0.6 -0.3 -0.5 0.1 -0.5 -0.2
Qualifications: nursing, teaching 0.3 0.5 1.6 0.4 -1.3 -0.0 -0.9 -0.8 -0.4 0.4 0.4
Commuting to job workplace: Walk 0.2 0.2 0.4 0.0 0.1 0.4 0.7 0.4 0.7 0.3 -0.3
Eye problems/disorders: Cataract 0.7 0.8 5.1 -0.2 -2.3 -0.3 0.5 0.3 0.4 -0.2 -0.6
Mouth/teeth dental problems: Mouth ulcers 0.9 1.4 3.3 1.1 -0.5 0.2 1.5 -1.8 0.5 -0.6 1.8
Medication for cholesterol 0.4 0.5 1.4 0.3 0.7 -0.0 -1.2 -1.0 -0.2 -1.1 0.1
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.7 0.8 2.1 -0.5 1.2 0.5 -1.4 -0.8 -0.3 1.2 -0.6
Back pain experienced in last month 1.4 2.0 3.5 -1.4 0.8 -1.9 -1.5 1.4 -1.8 0.8 1.5
Mineral and other dietary supplements 0.7 0.9 3.1 -0.3 1.8 -0.4 -0.8 -0.3 -0.8 1.6 -0.4
Breast cancer (self-reported) 0.3 0.3 1.0 -0.7 -0.1 -0.9 1.0 0.1 0.4 0.4 0.3
Asthma (self-reported) 0.1 0.1 0.4 -0.2 0.4 -0.6 -0.2 -0.4 -0.7 0.2 0.1
Osteoporosis (self-reported) 0.2 0.3 1.5 -0.3 1.2 0.4 -0.5 -0.0 0.3 -0.1 -0.4
Osteoarthritis (self-reported) 0.5 0.7 1.3 -1.0 0.9 -0.7 -0.2 0.7 -0.9 1.1 0.9
Medication: Aspirin 0.2 0.3 2.0 -1.4 0.2 -0.4 0.2 0.2 -0.3 0.2 0.0
Medication: Gliclazide 1.4 1.6 3.7 -0.8 0.5 -1.3 -1.9 -0.8 -1.9 0.9 1.1
Illnesses of father: None of the above (group 1) 0.4 0.5 1.5 -1.0 -0.1 0.8 0.8 -0.2 1.2 0.4 -0.7
Smoking status: Current 1.3 2.1 5.1 -1.2 0.9 -2.3 -0.9 1.1 -1.7 0.9 1.9
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.2 0.5 1.5 1.0 -1.2 0.4 0.0 0.9 0.2 -0.2 -0.7
Whole body water mass 0.3 1.5 5.8 0.9 1.4 -0.5 1.3 -0.5 0.3 -2.4 1.2
Leg predicted mass (right) 0.2 1.1 4.2 0.4 1.0 -1.0 0.4 -0.1 -0.5 -2.1 1.4
Arm fat mass (left) 0.3 1.2 3.3 0.3 0.6 -1.4 -1.7 0.4 -1.8 0.0 0.9
Number of self-reported non-cancer illnesses 0.6 1.0 3.0 -1.4 -0.5 -0.5 -0.3 -1.7 -0.9 0.2 1.1
Average weekly champagne plus white wine intake 0.5 0.7 1.3 -1.0 0.5 0.5 0.8 -0.9 1.1 0.9 -0.6
Miserableness 0.2 0.4 1.2 1.1 0.6 0.2 -0.5 -0.9 -0.1 -0.6 -0.2
Guilty feelings 0.7 1.1 2.5 1.2 -1.0 -0.9 0.2 1.1 -0.9 -0.7 1.6
Wears glasses or contact lenses 1.1 1.2 6.0 0.5 0.4 0.1 -0.7 -1.7 -0.5 2.4 0.0
Ever taken oral contraceptive pill 0.2 0.3 0.6 0.8 0.7 0.2 -0.5 -0.4 -0.5 -0.5 -0.2
Hearing aid user 0.5 0.6 1.3 0.1 0.8 0.3 1.1 0.6 1.0 -0.2 -1.1
Mother’s age at death 1.4 1.8 4.9 2.2 -1.5 1.4 0.2 -1.3 1.2 -0.7 -1.1
Financial situation satisfaction 0.9 1.2 3.6 1.9 -1.4 1.3 -0.1 -0.7 0.3 0.7 -0.9
Tinnitus: Yes, now most or all of the time 1.4 1.6 4.0 -1.7 0.8 -2.0 -1.2 0.4 -1.6 -0.9 0.8
Commuting to job workplace: Public transport 0.6 0.7 2.9 0.8 0.9 0.7 -0.3 0.2 -0.1 1.7 -0.7
Eye problems/disorders: Glaucoma 1.2 1.5 3.5 1.5 -0.7 1.8 -0.3 -1.1 0.8 0.4 -1.9
Medication: Blood pressure 0.5 1.0 3.6 -0.6 -1.0 0.7 1.2 -0.7 0.7 1.9 0.3
Pain type(s) experienced in last month: Hip pain 0.7 0.8 2.5 0.0 0.8 -0.6 -1.6 -0.2 -1.2 1.3 -0.5
Supplements: Fish oil (including cod liver oil) 1.2 1.5 5.9 1.2 -2.4 0.9 0.8 0.2 1.2 -1.3 -0.0
High cholesterol (Self-reported) 1.0 1.8 5.2 -1.1 -1.8 0.5 -0.0 -2.3 0.6 0.9 -1.7
Medication: Bendroflumethiazide 0.2 0.3 1.6 0.2 -0.1 0.1 1.3 0.0 0.4 0.5 0.5
Medication: Paracetamol 0.9 1.4 2.7 -0.6 1.3 -1.4 -1.6 1.1 -1.6 0.3 0.6
Medication: Lisinopril 0.8 1.1 3.0 -0.8 -0.1 -1.6 -0.3 -0.5 -1.4 0.6 1.7
Medication: Atorvastatin 0.4 0.5 1.8 0.7 -1.4 0.2 -0.6 -0.8 0.2 -0.0 -0.7
Illnesses of father: High blood pressure 1.0 1.3 4.1 1.6 2.0 -0.1 -1.4 -0.2 -1.2 0.1 0.4
Alcohol drinker status: Never 0.6 0.7 2.3 -0.3 -0.3 -0.5 -1.2 0.9 -1.5 -0.1 0.7
Ever smoked 0.8 1.5 5.1 -1.1 -0.3 -1.7 -0.3 0.6 -1.1 2.3 0.8
Basal metabolic rate 0.2 1.2 4.4 0.7 1.1 -0.8 0.8 -0.2 -0.2 -2.1 1.4
Leg fat percentage (left) 0.7 2.4 6.0 -0.3 0.1 -2.5 -1.8 1.1 -2.3 0.9 1.6
Arm fat-free mass (left) 0.4 1.8 7.0 0.9 1.3 -0.8 1.3 -0.3 0.2 -2.6 1.6
Number of operations (self-reported) 0.5 0.7 1.8 0.6 1.4 0.4 0.6 -1.3 0.4 -1.1 -0.1
Average weekly beer plus cider intake 1.0 1.4 8.2 0.2 0.2 -0.8 0.9 2.9 -0.2 -0.1 1.4
Irritability 0.4 0.7 1.7 1.1 -1.3 -0.2 -1.2 -0.3 -0.3 -0.7 -0.3
Risk taking 0.2 0.2 1.0 0.6 0.0 -0.5 1.0 0.3 0.0 0.3 0.5
Ever had prostate specific antigen (PSA) test 0.2 0.2 0.7 0.4 -0.4 -0.2 -0.3 0.2 -0.3 -0.8 0.5
Fractured/broken bones in last 5 years 0.7 0.9 4.7 0.3 -0.4 -1.0 0.6 0.7 -0.4 0.7 2.2
Age started oral contraceptive pill 1.5 1.9 6.7 -0.6 -0.7 0.4 2.1 2.6 1.4 0.9 0.4
Diastolic blood pressure, automated reading 0.4 1.1 2.2 -0.9 -1.4 -0.7 -1.5 -1.3 -1.1 0.9 0.0
Ever depressed for a whole week 0.4 0.5 1.9 1.4 0.1 0.4 -1.3 -0.4 -0.7 0.0 -0.3
Unable to work because of sickness or disability 1.8 2.3 5.7 -1.4 -0.1 -2.4 0.1 1.9 -1.7 0.3 2.0
Commuting to job workplace: Cycle 0.5 0.6 2.2 1.3 -0.1 0.6 0.2 -0.5 0.3 -1.5 0.5
Myopia 1.4 2.0 4.9 -0.8 1.1 -1.0 -1.9 -2.2 -1.9 0.7 0.9
Vascular/heart problems diagnosed by doctor 0.2 0.5 1.5 0.1 0.7 0.7 0.5 0.5 1.2 0.1 -1.1
Cholesterol lowering medication 1.2 1.8 5.9 -1.2 -1.2 -0.5 -1.8 -0.0 -1.0 2.4 -1.2
Medication: Omeprazole (e.g. Zanprol) 0.7 0.9 1.7 0.7 -0.4 1.2 1.2 -0.1 1.0 -1.3 -0.8
Pain experienced in last month 0.7 1.2 3.3 0.7 -0.3 1.8 0.1 -0.7 1.3 0.7 -1.8
Supplements: Calcium 0.4 0.4 1.3 -0.4 0.4 0.1 -1.2 0.6 -0.4 -0.8 0.6
Basal cell carcinoma (self-reported) 1.5 1.7 8.0 1.4 2.8 0.9 0.4 -1.3 0.7 -0.7 -0.5
Heart attack/myocardial infarction (self-reported) 0.5 0.6 1.5 1.2 0.6 1.1 0.0 -0.1 0.9 -0.8 -0.6
Deep venous thrombosis (DVT) (self-reported) 1.2 1.5 3.2 0.8 -1.8 0.7 1.7 0.2 1.8 -0.1 -1.4
Heart disease (siblings) 1.0 1.3 3.6 0.0 -0.3 -1.6 -0.9 0.2 -1.9 0.9 1.4
Alcohol drinker status: Previous 0.3 0.3 1.1 -0.2 -1.0 -0.1 -0.5 1.0 -0.0 0.4 -0.2
Pack years of smoking 0.3 0.5 1.9 0.6 0.9 0.5 -0.6 -0.0 -0.5 1.4 -0.3
Impedance of whole body 0.1 0.6 1.3 0.0 -1.0 1.1 -0.2 -0.3 0.9 1.1 -0.9
Leg fat mass (left) 0.5 2.1 5.5 -0.2 0.3 -2.4 -1.6 0.7 -2.2 0.2 1.7
Arm predicted mass (left) 0.4 2.0 7.1 1.0 1.7 -0.6 1.5 -0.5 0.4 -2.7 1.4