Hub : Genes

DHX8

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Brain Cerebellar Hemisphere	0.2080	0.1080	4.9e-03	0.014	NA	0.002	NA	0.034	1.4e-01	NA	2.9e-01	NA	4.8e-02
2	GTEx	Brain Cerebellum	0.1270	0.0600	4.7e-03	-0.010	NA	-0.010	NA	-0.009	8.6e-01	NA	9.3e-01	NA	7.4e-01
3	GTEx	Esophagus Mucosa	0.1480	0.0570	7.3e-03	0.076	NA	0.067	NA	0.054	8.2e-06	NA	2.8e-05	NA	1.6e-04
4	GTEx	Skin Not Sun Exposed Suprapubic	0.3530	0.0840	1.5e-09	0.263	NA	0.144	NA	0.246	1.1e-14	NA	2.8e-08	NA	9.9e-14
5	GTEx	Skin Sun Exposed Lower leg	0.4020	0.0570	1.4e-14	0.183	NA	0.236	NA	0.250	5.0e-15	NA	1.9e-19	NA	1.1e-20
6	TCGA	Breast Invasive Carcinoma	0.0146	0.0127	8.8e-03	0.006	0.006	0.003	NA	0.005	1.6e-02	0.0140	8.1e-02	NA	3.3e-02
7	TCGA	Brain Lower Grade Glioma	0.1586	0.0833	3.9e-05	0.046	0.023	0.017	NA	0.003	5.9e-06	0.0011	4.8e-03	NA	1.2e-01
8	TCGA	Prostate Adenocarcinoma	0.0526	0.0328	1.8e-03	0.016	0.024	0.014	NA	0.018	7.0e-03	0.0014	1.2e-02	NA	5.0e-03

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	0.6	1.0	2.9	0.3	-0.8	-0.2	0.7	1.1	-1.1	-1.7	-1.3
Bipolar Disorder or Schizophrenia	0.4	1.0	2.1	-0.9	-1.4	-0.3	0.9	0.6	-1.1	-1.5	-0.9
Depressed Affect (Nagel 2018)	0.3	0.7	3.3	0.1	0.0	-1.8	-0.2	-0.8	-0.6	-1.1	-0.3
Depression (Nagel 2018)	1.1	1.6	5.3	0.6	-0.8	2.3	2.3	1.1	-0.5	0.2	0.1
Intelligence (Savage-Jansen 2018)	0.5	1.5	4.1	0.5	0.4	2.0	0.5	1.0	1.2	1.6	1.4
Neuroticism (Nagel 2018)	0.2	0.4	1.6	-0.2	-1.0	-1.3	0.5	0.4	-0.1	-0.4	0.3
Schizophrenia (2018)	0.3	0.5	1.9	-1.4	-1.1	-0.2	0.6	-0.2	-0.6	-0.5	-0.1
Schizophrenia vs Biploar Disorder	1.7	2.2	4.2	-1.9	-0.1	1.2	0.4	0.2	2.0	2.1	2.0
Worry (Nagel 2018)	0.4	0.9	5.0	-0.8	-2.2	-0.8	0.6	0.5	0.2	-0.1	0.4
Alzheimer’s Disease (in mother)	0.4	0.5	1.6	-0.3	0.8	-1.3	-0.8	-0.9	0.4	-0.5	-0.2
Alzheimer’s Disease (in father)	0.2	0.2	0.4	0.6	0.6	-0.2	-0.7	-0.5	-0.1	0.2	0.3
Alzheimer’s Disease (including proxy)	0.2	0.3	0.8	0.4	0.6	-0.9	-0.5	-0.5	-0.5	-0.6	-0.1
Crohns Disease (2017)	1.3	2.8	6.5	-1.0	-0.3	-1.1	-2.5	-2.2	-1.8	-1.6	-1.7
Irritable Bowel Disease (IBD)	0.8	2.0	6.6	-1.2	-0.1	-0.7	-2.6	-2.2	-0.5	-1.3	-1.0
Ulcerative Colitis (UC)	0.3	0.6	1.8	-0.5	0.2	0.7	-1.4	-1.0	1.1	-0.4	0.4
Major Depression (MDD)	1.0	1.2	2.6	0.4	-1.1	-1.1	0.0	-1.3	-0.9	-1.3	-1.6
Reaction Time	1.7	3.2	6.0	0.1	-0.7	1.0	2.4	2.3	-2.5	-1.4	-2.3
Verbal and Numeric Reasoning (VNR)	0.2	0.5	1.2	-0.2	1.1	1.0	-0.3	0.1	0.6	1.0	0.8
Breast Cancer	0.5	1.3	5.7	0.7	-0.5	2.4	0.5	0.3	1.2	1.0	1.1
Ovarian Cancer	1.4	1.9	7.0	0.2	-0.7	1.0	2.3	2.6	0.3	1.0	0.4
Prostate Cancer	2.1	3.0	7.8	0.4	0.8	1.6	-1.8	-0.7	1.7	2.5	2.8
Age at First Birth	0.5	0.8	2.3	-0.4	0.7	1.5	0.2	0.4	1.0	1.0	1.1
Bipolar Disorder (2011)	0.9	0.9	3.2	-0.4	-1.8	-0.1	0.8	0.8	-0.9	-0.8	-1.1
Body Mass Index (BMI) (2010)	2.8	3.8	7.1	2.6	2.6	-0.7	-2.7	-2.4	1.3	1.1	0.9
Coronary Artery Disease (CAD)	0.5	0.6	2.9	-1.7	-0.7	-0.7	-0.2	0.1	0.9	0.4	0.5
Crohns Disease (2012)	0.7	1.1	2.1	-0.9	0.1	-0.6	-1.3	-1.4	-1.2	-1.1	-1.2
Mean Putamen Volume	0.6	0.6	2.9	-0.4	0.6	1.7	-0.6	-0.1	0.6	1.0	0.3
Fasting Glucose	1.6	1.9	6.6	-1.5	-0.3	-2.6	0.6	0.7	-0.8	-1.5	-1.6
HbA1C	2.8	3.2	8.8	-1.8	-2.2	1.4	2.5	3.0	-0.7	-0.4	-0.0
HDL Cholesterol	1.6	2.7	9.9	0.2	1.9	-0.8	-3.1	-2.6	-0.3	-0.5	-0.2
LDL Cholesterol	0.4	0.6	1.2	1.1	0.9	0.0	-0.7	-0.7	0.6	0.8	0.9
Lupus	2.1	3.2	6.0	-2.5	-1.3	1.6	2.1	2.2	1.4	1.0	1.7
Neuroticism (2016)	0.2	0.3	0.8	-0.5	-0.3	0.1	-0.5	-0.6	0.7	0.4	0.9
Primary Biliary Cirrhosis	0.1	0.2	0.5	0.5	0.2	-0.3	-0.4	-0.7	-0.1	0.0	-0.5
Rheumatoid Arthritis	0.5	0.7	1.9	-0.2	0.9	0.6	-0.5	-0.5	1.3	0.5	1.4
Schizophrenia (2014)	0.7	1.5	4.6	-2.1	-2.1	0.4	1.3	0.5	0.2	0.3	0.7
Triglycerides	3.0	4.9	19.6	-0.4	-0.7	0.8	4.4	4.3	-0.3	0.1	0.1
Type 2 Diabetes (T2D) (2012)	1.5	1.7	6.4	-2.5	-1.8	-0.8	1.3	1.1	0.2	-0.3	-0.6
Ulcerative Colitis	0.1	0.2	0.5	-0.7	-0.0	-0.2	-0.5	-0.2	0.6	-0.2	0.2
Blood Eosinophil Count	1.3	9.6	21.3	3.6	4.0	-1.1	-4.2	-4.6	2.0	1.9	0.9
Blood Platelet Count	0.3	3.4	11.7	3.4	1.7	-2.6	1.1	1.0	-1.5	-0.3	-1.2
Blood Red Count	0.2	2.0	6.2	-2.5	0.7	1.3	0.1	0.3	1.6	1.0	2.0
Blood White Count	2.5	18.6	55.2	4.9	7.4	-2.9	-5.8	-4.8	0.7	1.7	1.1
Heel T-Score	1.6	13.1	35.6	3.2	-1.2	-5.4	6.0	4.5	-1.3	1.6	-2.0
BMI	1.5	8.8	30.0	3.0	5.5	-3.8	-2.5	-1.9	2.2	0.9	1.2
Height	0.4	8.3	22.3	3.8	1.8	0.7	-2.3	-1.1	3.8	4.7	2.2
Waist Hip Ratio (WHR)	0.8	3.4	11.6	1.7	0.9	-0.5	3.3	3.4	-0.9	0.2	0.2
Systolic Blood Pressure	0.3	1.5	3.9	-1.0	-1.8	1.3	0.9	0.7	1.0	2.0	-0.1
Smoking Status	1.0	2.4	4.6	-0.4	-2.1	0.9	2.1	2.1	-1.7	-0.2	-1.4
Allergy or Eczema	0.1	0.3	0.9	-0.8	0.3	-0.2	-0.3	-1.0	-0.1	-0.6	0.0
Cardiovascular Disease	0.7	2.3	5.2	-0.8	-0.2	1.8	2.3	2.2	1.4	1.2	0.9
Hypothyroidism (self reported)	0.4	0.9	2.6	-1.6	-1.2	0.1	-1.1	-1.0	-0.1	-0.5	-0.6
Respiratory disease	0.5	1.2	3.0	0.3	-0.4	-0.5	-0.1	-1.5	-1.5	-1.2	-1.7
Type 2 Diabetes (T2D) (2018)	1.3	2.4	5.4	-0.7	0.6	-1.1	1.2	1.7	2.3	1.8	2.0
Lung FEV1/FVC ratio	1.1	5.5	11.3	0.7	3.2	2.0	-0.4	-0.6	3.0	3.0	3.4
Lung FVC	0.5	2.8	7.8	-1.2	-2.8	0.7	1.1	0.8	-2.5	-0.8	-2.0
Neuroticism	0.3	0.6	2.3	-0.5	-1.2	-1.5	0.3	-0.1	-0.3	-1.0	-0.1
Chronotype (morning person)	0.8	1.8	3.9	-0.8	0.6	1.5	0.6	1.1	2.0	1.5	1.9
Hair Pigment	0.1	2.9	8.5	-0.4	1.7	1.1	-1.1	-0.3	2.9	1.6	2.6
Tanning	0.2	2.1	7.4	-1.0	-2.7	0.1	1.2	1.1	-1.7	-1.2	-1.4
Hand grip strength (left)	0.9	2.3	7.6	-2.8	-2.0	0.2	1.4	1.3	1.2	1.1	0.7
Number of treatments/medications taken	0.3	0.6	1.4	-0.8	-1.2	1.0	1.0	0.6	0.4	-0.2	0.0
Average weekly spirits intake	1.5	1.8	6.5	-0.5	-0.9	2.5	1.5	1.4	0.7	1.0	1.1
Sensitivity / hurt feelings	0.6	1.0	3.1	-1.7	0.3	-0.1	1.0	1.2	0.7	-0.3	1.4
Frequency of depressed mood in last 2 weeks	0.5	0.7	2.2	0.5	-0.4	1.4	0.5	-0.1	-1.5	-0.3	-0.8
Hearing difficulty/problems: Yes	0.6	0.9	1.8	0.8	0.4	-0.9	-1.0	-0.9	-1.3	-0.9	-1.1
Relative age of first facial hair	0.7	1.4	3.9	-1.2	-0.0	0.6	2.0	1.4	0.9	0.6	1.4
Other serious medical condition/disability diagnosed by doctor	0.6	0.8	2.5	-0.6	-0.7	0.7	1.6	1.5	0.3	0.4	0.5
Ever used hormone-replacement therapy (HRT)	2.0	2.5	6.1	2.5	2.3	1.1	-1.5	-0.8	0.8	1.6	1.2
Ever had hysterectomy (womb removed)	1.0	1.2	3.3	1.4	0.1	-0.8	-0.8	-0.5	-1.4	-0.8	-1.8
Systolic blood pressure, automated reading	0.2	0.7	2.2	1.2	0.4	0.4	-0.6	-0.9	0.4	1.5	-0.4
Eye problems/disorders: Diabetes related eye disease	0.9	1.0	3.6	-0.4	-0.7	0.2	1.7	1.9	-0.2	0.6	0.4
Angina	0.8	1.0	2.3	-0.5	0.9	0.3	-0.0	0.4	1.5	1.5	1.5
Medication for hormone replacement therapy	0.3	0.3	1.1	0.1	-0.4	-0.5	-1.1	-0.7	-0.3	0.5	-0.4
Vitamin and mineral supplements	0.9	1.2	4.0	0.7	2.0	0.3	-1.2	-0.6	-1.4	-0.8	-0.8
Supplements: Zinc	1.6	1.7	3.4	-1.8	-1.8	1.1	0.4	0.0	1.6	1.1	1.6
Medication: Co-codamol	0.9	1.1	3.2	0.3	0.1	0.0	0.1	-0.3	1.7	1.8	1.6
Medication: Metformin	2.0	2.8	7.2	0.8	1.8	-0.9	0.7	1.0	2.7	1.9	2.2
Diabetes (father)	0.4	0.5	1.3	-0.1	0.3	0.4	-0.3	-0.1	1.1	1.0	1.1
Diabetes (mother)	0.9	1.2	2.7	0.8	1.5	0.1	-1.6	-1.4	0.5	0.1	1.2
Severe depression (siblings)	3.7	4.1	8.1	-2.8	-2.9	1.5	2.6	2.7	-0.4	-0.4	-0.0
Pack years adult smoking proportion	0.7	1.0	3.3	-0.5	-0.4	0.9	0.5	0.4	1.6	0.8	1.8
Impedance of leg (right)	0.3	1.5	8.2	-0.4	-2.9	0.4	1.3	0.9	-0.5	0.8	0.4
Leg fat-free mass (left)	0.8	4.3	15.7	2.2	4.0	-1.4	-1.6	-0.9	2.3	1.7	1.0
Trunk fat percentage	1.7	6.7	23.0	4.5	4.8	-2.7	-1.7	-0.6	0.3	0.2	0.1
Hand grip strength (right)	1.2	3.2	8.7	-2.9	-2.9	-0.7	1.9	1.7	1.1	0.6	0.4
Townsend deprivation index at recruitment	0.3	0.5	1.4	0.3	-0.1	0.6	-0.7	-0.7	-0.6	-1.2	-0.7
Current tobacco smoking	1.5	2.4	7.7	0.0	-1.5	0.9	0.8	0.8	-2.8	-1.2	-2.4
Average weekly fortified wine intake	3.5	4.1	9.8	-1.8	-2.4	3.1	3.0	2.1	0.3	0.7	0.4
Maternal smoking around birth	0.6	0.8	2.7	-1.6	-0.5	0.3	-0.4	-0.5	-0.9	-1.4	-0.7
Fed-up feelings	0.3	0.5	1.0	1.0	1.0	0.5	-0.3	0.0	-0.6	-0.9	-0.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.5	1.7	1.1	1.3	0.8	0.1	-0.4	-0.4	0.1	0.1
Relative age voice broke	1.3	1.9	6.9	-1.3	-0.7	0.1	2.6	2.4	0.7	-0.3	0.3
Taking other prescription medications	0.2	0.3	1.4	-0.0	-0.6	-0.1	-0.0	-0.1	-0.3	-0.6	-1.2
Age when periods started (menarche)	1.6	3.9	11.2	-1.3	-0.7	0.8	0.3	0.7	3.0	2.7	3.4
Bilateral oophorectomy (both ovaries removed)	0.9	1.0	2.3	-0.3	-0.5	0.3	1.1	1.1	-1.5	-1.1	-1.3
Heel bone mineral density (BMD) T-score, automated (left)	1.2	2.7	9.9	1.8	1.0	-3.1	1.6	1.9	-0.5	-0.0	-1.2
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	0.5	0.4	-0.7	0.7	0.3	-0.2	0.0	0.3	-0.3
Qualifications: CSEs or equivalent	0.4	0.5	1.4	-0.9	-0.9	-1.2	0.7	-0.1	0.3	0.3	-0.3
Serious illness, injury or assault to yourself	0.4	0.5	1.3	-0.3	1.1	0.4	-0.2	0.2	1.1	0.5	0.6
High blood pressure	0.3	0.9	3.1	-0.5	0.9	1.8	0.8	1.5	0.1	-0.4	-0.2
Hayfever, allergic rhinitis or eczema	0.1	0.2	0.6	-0.3	0.7	-0.8	0.3	-0.6	-0.1	-0.2	-0.3
Multivitamins +/- minerals	0.4	0.5	1.2	0.5	0.1	-0.3	-0.6	-0.7	1.1	1.1	0.4
Stomach or abdominal pain in last month	0.4	0.5	1.4	0.1	-0.7	0.3	0.5	0.1	-0.9	-1.2	-0.6
Supplements: Glucosamine	1.4	1.9	6.8	2.6	1.9	-0.8	-1.3	-1.0	0.8	0.6	-0.1
Diverticular disease/diverticulitis (self-reported)	0.6	0.8	2.2	0.1	-0.2	-0.4	1.5	1.2	0.6	1.3	0.4
Medication: Atenolol	0.2	0.2	1.3	0.2	-0.2	-1.2	0.2	0.2	0.0	0.1	-0.2
Medication: Levothyroxine sodium	0.6	1.0	3.7	-0.7	-0.2	-0.2	-1.9	-1.9	0.4	-0.0	0.4
Sitting height	0.8	5.6	12.7	2.3	3.6	-0.8	-2.9	-1.5	2.9	2.2	1.6
Chronic bronchitis/emphysema (father)	0.1	0.1	0.2	0.3	-0.0	-0.4	-0.5	-0.2	0.3	0.4	0.1
High blood pressure (mother)	0.8	1.2	5.4	-0.0	-0.4	-0.2	-0.1	0.1	-2.3	-1.3	-1.5
Body mass index (BMI)	1.1	4.5	19.4	2.4	4.4	-2.8	-1.5	-0.9	0.3	-0.6	-0.2
Impedance of leg (left)	0.3	1.6	8.9	-0.4	-3.0	0.6	1.1	1.0	-0.8	0.4	0.3
Leg predicted mass (left)	0.8	4.5	16.2	2.2	4.0	-1.4	-1.6	-0.9	2.3	1.7	1.1
Trunk fat mass	1.7	7.2	25.6	4.4	5.1	-2.6	-1.8	-0.6	1.0	0.9	0.5
Waist circumference	1.3	4.9	20.1	3.7	4.5	-2.2	-0.7	-0.2	0.4	0.1	0.3
Number of incorrect matches in round	1.8	3.0	7.3	-1.5	0.0	1.4	-1.5	-1.1	2.5	2.7	1.7
Past tobacco smoking	1.4	2.7	6.3	-0.3	1.6	-1.3	-2.5	-2.5	1.7	0.3	1.2
Alcohol usually taken with meals	0.6	0.9	2.2	-1.2	-0.6	-0.3	-0.5	-0.9	1.3	0.7	1.5
Nervous feelings	0.4	0.8	2.3	1.1	0.3	-0.3	-0.7	-0.6	1.0	1.5	1.1
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.7	2.3	-0.7	-1.1	0.5	1.5	0.8	-0.0	0.2	0.2
Hearing difficulty/problems with background noise	1.2	1.9	5.1	1.0	0.8	-0.7	-0.2	-0.7	-2.3	-1.8	-2.0
Hair/balding pattern: Pattern 2	0.5	0.6	2.7	-1.6	0.1	1.0	0.1	-0.1	0.6	0.2	0.9
Had menopause	3.6	4.4	15.8	4.0	2.3	0.1	-2.5	-2.2	-0.9	-0.7	-1.4
Had other major operations	1.0	1.3	3.4	1.1	0.2	0.6	1.8	1.9	-1.0	-0.7	-0.7
Forced vital capacity (FVC)	0.1	0.2	1.0	0.1	-0.6	0.0	0.4	0.4	0.5	1.0	0.1
Heel bone mineral density (BMD) T-score, automated (right)	1.1	2.4	9.6	1.4	0.2	-3.1	1.7	1.8	-0.1	0.8	-0.7
Ever unenthusiastic/disinterested for a whole week	0.6	0.8	2.0	-0.7	-0.8	-0.3	-0.0	-0.5	-1.2	-1.4	-1.2
Qualifications: None of the above	0.8	1.8	5.1	1.9	0.2	-0.1	-0.1	0.1	-1.7	-2.3	-1.6
Financial difficulties in last 2 years	0.8	1.0	2.7	-1.6	0.5	-0.4	1.2	0.9	-1.1	-1.2	-0.6
Mouth/teeth dental problems	1.4	2.1	7.0	-0.5	-0.0	2.7	-0.2	-0.7	1.3	2.3	1.5
Heart attack	0.8	1.0	2.5	-0.3	1.5	-0.5	0.7	0.6	1.1	1.2	1.6
Allergy	0.1	0.3	0.7	0.5	-0.7	0.1	-0.8	0.1	0.3	0.7	0.4
Pain all over the body in last month	0.4	0.4	1.1	0.8	0.0	-0.8	-0.9	-1.0	0.2	0.0	0.2
Diabetes (self-reported)	1.3	2.0	3.9	0.3	1.1	-1.0	1.0	1.6	1.8	2.0	1.6
Hayfever/allergic rhinitis (self-reported)	0.5	0.7	1.7	0.4	0.5	-1.1	-1.3	-1.3	-0.1	-0.7	-0.4
Medication: Ramipril	1.8	2.3	7.9	2.8	2.3	0.1	-1.1	-1.0	1.0	0.8	0.8
Medication: Simvastatin	0.6	0.9	2.6	0.1	0.9	-0.2	0.2	0.9	1.6	1.3	1.0
Fluid intelligence score	0.0	0.1	0.2	-0.5	-0.4	0.3	0.3	0.2	-0.2	0.4	0.1
Illnesses of siblings	0.9	1.3	2.9	-1.7	-1.4	-1.0	-0.8	-1.2	-0.7	-0.7	-1.0
Neuroticism score	0.2	0.4	1.3	0.4	-0.4	-1.2	-0.5	-0.9	-0.0	-0.2	0.4
Weight	1.1	5.4	20.6	3.2	4.5	-2.2	-1.6	-0.6	1.6	1.1	0.6
Impedance of arm (right)	0.2	1.0	4.3	0.2	-2.1	0.2	1.2	0.9	-1.0	-0.3	-0.6
Arm fat percentage (right)	1.4	5.3	18.5	3.2	4.3	-3.4	-1.2	-0.7	-0.3	-0.6	-0.5
Trunk fat-free mass	0.4	2.4	5.2	1.1	2.2	-0.8	-1.1	-0.7	2.3	2.1	1.0
Hip circumference	1.0	4.5	12.5	2.8	3.5	-1.9	-2.5	-2.0	1.2	0.4	0.5
Time employed in main current job	0.3	0.4	1.4	1.2	0.2	0.1	0.5	0.4	-0.8	-0.3	-0.6
Alcohol intake versus 10 years previously	0.4	0.6	3.1	-1.8	0.1	-0.1	0.6	0.8	0.1	-0.8	-0.0
Father’s age at death	0.9	1.2	6.2	0.4	-0.5	2.5	-0.2	1.0	0.3	0.8	1.0
Worrier / anxious feelings	0.9	1.7	5.2	-1.7	-2.3	0.6	0.8	0.7	0.9	0.7	1.6
Frequency of tiredness / lethargy in last 2 weeks	1.0	1.6	4.5	-0.0	-2.1	0.4	1.5	0.6	-1.7	-0.6	-1.5
Falls in the last year	1.1	1.5	6.8	0.3	-1.4	-0.2	0.6	0.3	1.2	2.6	1.1
Hair/balding pattern: Pattern 3	0.7	1.1	2.6	1.6	1.0	1.2	0.2	1.1	0.4	1.1	1.1
Number of live births	1.1	1.5	4.9	-0.5	0.9	-1.3	0.1	0.1	-1.6	-2.2	-1.5
Forced expiratory volume in 1-second (FEV1)	0.4	1.3	4.4	-0.3	-0.1	0.7	0.6	0.6	1.7	2.1	1.5
Pulse rate	0.5	0.8	1.9	-1.1	-0.6	1.0	0.9	1.4	-0.8	-0.3	0.3
Happiness	0.6	0.7	2.6	0.1	1.3	1.6	0.0	0.3	-0.6	-0.9	-0.2
Noisy workplace	1.0	1.2	2.0	0.8	0.4	-1.4	-0.8	-1.1	-1.1	-1.4	-1.4
Qualifications: A levels/AS levels or equivalent	1.2	2.7	8.7	0.8	1.9	-0.5	-3.0	-2.7	0.5	0.7	0.4
Serious illness, injury or assault of a close relative in last 2 years	0.8	0.9	3.7	0.1	-0.6	0.3	0.6	0.3	-1.4	-1.0	-1.9
Mouth/teeth dental problems: Dentures	1.0	1.7	4.3	0.6	0.2	-1.0	1.1	1.4	-1.3	-2.1	-1.8
Asthma	0.3	0.5	1.6	-0.3	-0.1	0.2	0.0	-1.2	-0.7	-1.1	-0.9
Medication: Ibuprofen (e.g. Nurofen)	1.1	1.4	3.8	-1.0	-1.4	0.8	-0.1	-0.0	1.3	1.4	2.0
Medication: Cholesterol lowering	0.8	1.3	4.2	0.6	2.0	-0.6	-0.4	0.1	1.7	1.4	0.8
Depression (self-reported)	0.6	0.8	2.2	0.5	-0.8	1.0	-0.4	-0.9	-1.5	-0.3	-1.0
Medication: Lansoprazole	0.1	0.2	0.6	-0.3	-0.4	0.1	0.4	0.2	0.5	0.8	0.2
Prospective memory result	0.3	0.4	1.2	1.1	0.2	0.7	0.4	0.8	0.6	-0.6	0.4
Lung cancer (father)	0.2	0.3	0.9	-0.2	0.3	-0.3	-0.6	-0.9	-0.9	-0.1	-0.1
Illnesses of mother	0.7	0.9	3.3	-0.1	0.9	0.1	0.8	0.9	1.8	0.8	0.8
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.5	2.1	-0.3	0.0	0.3	0.1	0.1	1.0	1.5	0.7
Pulse wave Arterial Stiffness index	0.6	0.7	2.1	0.7	0.2	1.1	0.2	0.5	-1.4	-0.7	-0.9
Impedance of arm (left)	0.2	0.8	3.5	1.0	-1.9	0.6	0.4	0.2	-1.0	0.0	-0.5
Arm fat mass (right)	1.3	5.3	20.0	3.3	4.5	-3.0	-1.2	-0.5	0.8	0.3	0.2
Trunk predicted mass	0.4	2.5	5.5	1.1	2.2	-0.7	-1.2	-0.8	2.4	2.2	1.1
Standing height	0.5	4.6	16.2	2.1	0.7	0.8	-0.1	0.7	3.2	4.0	2.0
Length of working week for main job	0.6	0.7	2.5	0.8	-0.4	0.2	1.6	1.2	-0.6	0.1	-0.1
Exposure to tobacco smoke at home	1.4	1.6	4.8	-0.6	-0.3	-1.5	0.7	1.2	-1.1	-2.2	-1.4
Breastfed as a baby	0.9	1.1	2.1	1.1	-1.3	0.1	1.0	1.1	-1.4	-0.4	-1.3
Tense / ‘highly strung’	0.9	1.4	2.9	-1.7	-1.6	0.8	1.4	1.4	0.8	0.5	0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	0.6	1.0	2.9	0.2	-0.2	0.7	1.7	1.7	-0.9	-0.5	-0.7
Hair/balding pattern: Pattern 4	0.3	0.8	2.0	0.1	-0.4	0.7	0.2	0.1	-1.3	-1.3	-1.4
Birth weight of first child	0.4	0.8	3.4	-0.5	-1.8	-0.6	0.2	-0.3	-0.7	-0.8	-1.2
Peak expiratory flow (PEF)	1.7	4.0	9.3	-0.7	0.3	1.8	1.2	1.4	3.0	2.9	2.8
Pulse wave reflection index	0.6	0.8	2.1	0.6	0.0	0.2	-0.4	-0.8	-0.9	-1.4	-1.5
Ever highly irritable/argumentative for 2 days	2.8	3.4	7.0	1.2	-1.9	-1.9	1.1	0.7	-2.6	-1.8	-2.5
Loud music exposure frequency	1.0	1.1	4.4	-2.1	-0.6	-0.9	-0.5	-0.1	-0.3	-1.7	0.1
Qualifications: O levels/GCSEs or equivalent	0.5	0.8	2.1	-1.4	-0.3	-1.1	-0.8	-1.1	-0.7	-0.5	-0.7
Mouth/teeth dental problems: Bleeding gums	0.1	0.1	0.6	0.7	0.1	-0.1	-0.3	0.4	0.2	-0.1	0.2
Blood clot in the leg (DVT)	0.2	0.2	0.7	0.2	0.8	0.1	0.0	0.4	0.8	0.2	0.1
Medication: Paracetamol	1.2	2.0	5.2	-1.3	-2.3	1.4	1.4	0.8	1.2	1.2	1.3
Headache pain in last month	1.5	2.5	10.7	-2.3	-3.3	0.7	0.7	0.5	0.9	0.8	1.1
Medication for cholesterol, blood pressure or diabetes	0.4	0.6	2.4	-0.5	-1.5	0.1	0.2	-0.6	-1.1	-0.5	-0.5
Glaucoma (self-reported)	0.2	0.2	0.9	0.2	-0.4	0.1	0.4	1.0	0.2	-0.6	-0.1
Gout (self-reported)	0.8	1.1	3.8	0.4	2.0	-0.8	-1.8	-0.9	0.1	0.0	0.1
Hypothyroidism/myxoedema (self-reported)	0.8	1.5	4.3	-1.7	-1.0	-0.3	-1.8	-2.1	0.3	-0.7	-0.2
Medication: Amlodipine	0.9	1.3	2.1	1.4	1.4	-1.2	-0.3	0.1	-0.8	-1.5	-1.4
Medication: Ventolin 100micrograms inhaler	0.2	0.3	1.0	-0.4	-0.0	1.0	0.6	0.1	0.5	0.7	0.1
Birth weight	0.6	1.3	3.5	1.9	1.4	0.2	0.4	0.8	-1.1	-1.3	-1.0
Chronic bronchitis/emphysema (mother)	0.5	0.6	1.0	-1.0	-0.8	0.9	-0.5	-0.7	0.6	0.7	0.6
High blood pressure (siblings)	0.3	0.4	1.2	1.1	0.6	-0.1	0.4	0.8	0.4	0.0	0.7
Forced vital capacity (FVC), Best measure	0.0	0.1	0.5	0.1	-0.7	-0.3	0.1	0.1	0.3	0.4	-0.2
Body fat percentage	1.8	7.0	23.7	4.4	4.9	-3.1	-1.7	-0.6	-0.0	-0.2	-0.1
Leg fat percentage (right)	1.6	5.7	20.8	3.7	4.6	-2.8	-1.6	-0.7	-0.3	-0.3	-0.1
Arm fat-free mass (right)	0.6	3.1	8.2	1.8	2.9	-0.9	-1.3	-0.6	2.2	1.9	1.2
Exposure to tobacco smoke outside home	1.3	1.7	4.3	-0.4	-0.1	1.9	0.9	0.8	1.4	1.4	2.1
Comparative body size at age 10	0.1	0.3	1.1	0.8	0.5	-1.1	0.4	-0.1	-0.7	0.2	0.1
Number of full brothers	0.6	0.7	4.0	2.0	0.6	-0.1	0.2	0.4	-0.4	-0.4	-0.8
Worry too long after embarrassment	0.3	0.4	1.2	1.1	-0.6	0.1	0.7	1.0	-0.2	0.4	0.4
Seen a psychiatrist for nerves, anxiety, tension or depression	1.4	1.8	4.0	1.4	1.2	0.5	0.0	-0.1	-1.9	-1.7	-2.0
Wheeze or whistling in the chest in last year	0.6	1.0	2.5	-0.2	-1.6	-1.1	-0.3	-1.3	-0.9	-0.8	-1.1
Number of children fathered	0.1	0.1	0.4	-0.3	0.2	0.6	0.1	-0.0	0.2	0.0	-0.0
Reason for reducing amount of alcohol drunk: Health precaution	2.4	2.8	4.7	-0.7	-1.3	1.4	2.2	2.0	1.6	1.9	1.9
Age at first live birth	0.8	1.4	3.6	-1.2	-0.1	0.0	0.5	1.0	1.4	1.9	1.8
Pulse wave peak to peak time	0.9	1.1	3.2	-0.3	0.3	-1.2	-0.5	-0.8	1.8	1.2	1.2
Health satisfaction	0.3	0.4	1.3	-0.3	-0.5	-0.1	0.5	1.1	-0.1	-0.5	-0.8
Shortness of breath walking on level ground	2.0	2.4	7.5	0.5	-0.4	-0.4	1.1	0.7	-2.0	-2.4	-2.7
Qualifications: College or University degree	0.2	0.6	1.4	-0.4	0.1	-0.6	-1.2	-1.1	0.9	0.9	0.7
Eye problems/disorders: None of the above	1.1	1.3	3.7	-0.2	0.6	-1.9	-1.4	-1.3	-0.8	-0.3	-1.3
Mouth/teeth dental problems: Loose teeth	1.1	1.4	4.9	1.3	2.2	-0.7	-0.6	-0.2	0.9	1.1	1.1
Emphysema/chronic bronchitis	0.8	0.9	2.9	-1.7	-1.0	0.3	0.7	0.2	-0.9	-1.3	-0.7
Medication for pain relief, constipation, heartburn	0.9	1.6	3.0	0.7	0.7	-1.7	-0.4	-0.6	-1.7	-1.7	-1.6
Neck or shoulder pain in last month	1.4	1.9	4.5	-1.7	-2.1	-0.5	2.1	1.9	-0.4	-0.0	-0.2
Medication: Blood pressure	0.3	0.5	1.5	-0.5	1.2	-0.5	0.2	1.2	0.5	-0.5	0.2
Angina (self-reported)	0.8	1.1	2.6	-0.5	0.9	0.4	-0.0	0.2	1.5	1.5	1.6
Migraine (self-reported)	2.6	3.2	6.2	-2.5	-2.5	0.9	2.4	1.9	1.1	0.7	1.4
Medication: Ibuprofen	1.7	2.1	3.6	-1.7	-1.3	1.8	0.8	1.1	1.2	1.4	1.9
Medication: Allopurinol	1.1	1.5	6.0	0.7	2.4	-1.2	-1.6	-0.7	0.2	-0.9	0.2
Medication: Omeprazole	0.4	0.5	2.8	0.2	1.7	0.7	0.4	0.3	0.4	0.2	-0.1
Medication: Seretide 50 evohaler	0.4	0.5	2.8	-0.2	0.0	1.7	0.8	0.4	-0.1	0.4	0.2
Mean time to correctly identify matches	2.3	4.4	9.6	0.8	-0.7	1.0	2.3	2.6	-3.1	-1.6	-2.8
Heart disease (mother)	1.0	1.2	2.6	1.0	-0.3	-1.5	0.6	0.0	-1.6	-1.1	-1.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.3	1.6	3.3	0.6	-0.2	-0.2	-1.0	-1.5	-1.8	-1.7	-1.7
Whole body fat mass	1.7	7.0	24.7	4.1	5.0	-3.0	-1.9	-0.8	0.8	0.7	0.4
Leg fat mass (right)	1.6	6.2	22.5	3.6	4.7	-3.1	-1.7	-0.8	0.6	0.3	0.3
Arm predicted mass (right)	0.6	3.2	9.3	1.9	3.0	-1.1	-1.4	-0.5	2.2	1.8	1.1
Pulse rate, automated reading	0.4	1.4	5.1	-0.9	-0.6	1.2	1.6	2.2	0.1	0.8	0.6
Alcohol intake frequency.	0.4	0.8	2.4	-1.6	0.6	0.1	0.6	-0.3	-1.0	-1.5	-0.4
Comparative height size at age 10	0.5	2.9	8.2	2.6	0.2	0.1	-1.8	-1.3	1.7	2.9	0.8
Number of full sisters	2.6	3.1	4.5	1.2	1.9	-2.0	-2.1	-2.0	-1.3	-1.8	-1.6
Suffer from ‘nerves’	0.3	0.4	1.4	0.6	-1.2	-0.5	0.5	0.5	0.7	0.1	0.4
Overall health rating	1.3	2.7	5.3	-0.3	-1.4	-0.7	1.5	1.1	-2.2	-2.3	-2.3
Chest pain or discomfort	2.7	3.8	10.0	-1.1	-3.2	-0.1	2.0	1.0	-2.6	-1.9	-2.0
Had major operations	0.2	0.3	0.6	-0.1	-0.6	0.5	-0.6	-0.6	-0.5	-0.8	0.0
Age at last live birth	0.8	1.2	2.2	-0.9	0.3	-0.2	1.4	1.5	0.9	1.2	1.4
Family relationship satisfaction	0.5	0.6	2.1	1.4	1.5	0.9	-0.1	-0.1	-0.3	0.1	0.0
Leg pain on walking	0.6	0.8	1.8	0.2	-1.3	-1.1	0.8	0.6	-0.7	-0.7	-1.2
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.3	0.9	-0.2	-0.1	-0.4	0.4	0.1	0.6	0.6	1.0
Commuting to job workplace: Car/motor vehicle	0.9	1.0	2.7	1.1	0.2	-0.6	0.2	0.6	-1.7	-1.0	-1.4
Illness, injury, bereavement, stress in last 2 years	2.1	2.6	6.7	1.9	1.6	-1.2	-2.6	-2.0	1.0	0.4	1.0
Medication: Aspirin	0.6	0.8	2.6	0.2	1.6	-0.5	-1.3	-0.8	0.5	1.1	0.0
Supplements: Vitamin C	2.1	2.5	6.1	-1.9	-2.5	0.5	2.5	1.6	0.9	0.4	0.7
Knee pain experienced in last month	0.5	0.7	2.9	1.7	1.2	-0.8	-0.4	-0.3	-0.2	-0.2	-0.5
Hypertension (Self-reported)	0.4	1.0	3.5	-0.4	0.6	1.9	1.1	1.6	0.1	-0.2	-0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.1	0.5	0.3	0.7	-0.2	-0.3	-0.4	-0.4	0.1	-0.3
Illnesses of father: Heart disease	0.6	0.9	3.0	-0.6	-0.9	-1.0	0.9	0.3	1.7	0.6	0.9
Illnesses of siblings: Diabetes	0.2	0.3	0.7	-0.4	-0.4	0.2	0.6	0.8	-0.2	-0.8	-0.4
Smoking status: Previous	0.9	1.3	4.1	-0.1	-0.5	1.1	2.0	2.0	0.2	0.9	0.4
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.5	1.2	-0.6	0.2	-1.1	-0.9	-0.7	-0.6	0.0	-0.7
Whole body fat-free mass	0.6	3.2	9.2	1.6	3.0	-1.0	-1.3	-0.7	2.4	2.0	1.1
Leg fat-free mass (right)	0.7	3.6	13.1	2.0	3.6	-1.3	-1.6	-0.9	2.0	1.4	0.8
Arm fat percentage (left)	1.5	6.0	20.7	3.7	4.5	-3.1	-1.6	-0.9	-0.3	-0.5	-0.4
Average weekly red wine intake	0.8	1.2	3.5	-0.9	-1.6	-0.4	1.4	1.9	0.0	0.4	-0.4
Handedness (chirality/laterality): Left-handed	1.6	1.9	3.4	-0.7	-1.4	1.7	1.9	1.4	1.0	1.6	1.1
Mood swings	0.1	0.1	0.3	-0.3	-0.5	-0.5	0.2	0.2	-0.5	-0.2	0.1
Loneliness, isolation	1.9	2.7	6.2	1.1	2.3	-0.7	-2.4	-2.5	1.1	0.6	1.0
Long-standing illness, disability or infirmity	1.4	2.1	5.8	-1.2	-1.6	1.3	2.4	2.1	-0.9	0.1	-0.3
Ever had bowel cancer screening	0.1	0.1	0.3	0.5	0.1	0.6	-0.2	-0.3	0.4	-0.1	0.1
Diabetes diagnosed by doctor	1.2	2.0	4.3	-0.1	0.8	-0.7	1.4	2.1	1.7	1.6	1.7
Ever had stillbirth, spontaneous miscarriage or termination	0.7	0.8	2.6	-0.3	-0.5	-1.1	0.2	-0.4	-1.4	-1.6	-0.6
Friendships satisfaction	0.7	0.9	3.2	0.9	1.8	0.0	-0.2	-0.3	1.5	0.5	0.4
Qualifications: nursing, teaching	1.0	1.6	4.9	-1.0	-2.2	1.3	1.7	1.1	0.6	1.0	0.3
Commuting to job workplace: Walk	0.6	0.7	1.8	-0.1	0.5	-1.2	-1.2	-1.4	-0.0	-0.3	-0.6
Eye problems/disorders: Cataract	0.8	0.9	2.2	-0.5	-0.7	1.5	1.0	1.5	1.0	-0.1	0.4
Mouth/teeth dental problems: Mouth ulcers	2.4	3.8	9.3	-0.2	-1.1	-3.0	-0.4	-0.5	-2.2	-2.9	-2.5
Medication for cholesterol	0.2	0.3	0.5	-0.6	-0.7	-0.6	0.7	0.2	0.2	-0.7	0.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.7	0.8	3.1	-0.5	-1.1	1.8	0.2	-0.1	0.6	1.3	0.4
Back pain experienced in last month	1.6	2.3	6.8	-0.0	-0.5	-1.1	0.1	-0.0	-2.6	-2.0	-2.5
Mineral and other dietary supplements	0.7	1.0	2.5	-1.6	0.4	-0.9	-0.2	0.0	-1.5	-1.2	-0.8
Breast cancer (self-reported)	0.6	0.7	2.0	0.8	-0.3	0.4	-0.6	-0.4	-1.1	-1.2	-1.4
Asthma (self-reported)	0.3	0.6	2.5	-0.2	0.1	-0.1	-0.4	-1.6	-0.4	-1.0	-0.7
Osteoporosis (self-reported)	0.2	0.3	1.9	0.1	0.0	-0.0	-0.6	-0.3	0.1	0.1	1.4
Osteoarthritis (self-reported)	1.0	1.3	6.9	1.2	0.7	-2.6	-0.1	0.1	-0.4	-0.8	-0.9
Medication: Aspirin	0.3	0.4	1.2	-0.4	1.1	-0.7	-0.8	-0.3	0.1	0.8	-0.3
Medication: Gliclazide	2.4	2.7	7.2	1.1	1.8	-1.6	-0.2	0.0	2.7	1.4	2.2
Illnesses of father: None of the above (group 1)	0.6	0.7	2.3	0.2	-0.2	0.9	-0.4	-0.1	-1.5	-0.7	-1.4
Smoking status: Current	1.6	2.6	8.3	-0.1	-1.8	0.8	1.0	0.9	-2.9	-1.1	-2.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.7	2.9	-0.4	-0.0	1.3	-0.3	-0.4	0.3	1.7	0.7
Whole body water mass	0.5	2.8	7.7	1.3	2.8	-0.9	-1.1	-0.6	2.4	2.0	1.1
Leg predicted mass (right)	0.7	3.6	13.7	2.1	3.7	-1.3	-1.6	-0.8	2.0	1.3	0.7
Arm fat mass (left)	1.3	5.5	20.4	3.6	4.5	-2.9	-1.4	-0.7	0.6	0.2	0.0
Number of self-reported non-cancer illnesses	0.4	0.8	1.6	-0.7	-0.6	0.6	1.0	1.2	-0.7	-0.8	-1.1
Average weekly champagne plus white wine intake	0.2	0.3	1.1	-0.3	0.7	0.1	-0.6	-0.3	1.1	0.3	0.7
Miserableness	2.2	3.8	13.2	0.5	0.8	-3.6	-1.6	-1.7	-1.8	-2.0	-1.9
Guilty feelings	0.3	0.4	1.0	0.2	0.6	-1.0	-0.8	-0.9	0.2	0.5	0.1
Wears glasses or contact lenses	0.3	0.4	1.3	0.4	0.7	0.6	-0.3	0.6	-0.0	-1.1	-0.2
Ever taken oral contraceptive pill	1.0	1.1	2.2	0.3	0.6	-0.4	-1.3	-1.4	1.0	1.5	0.9
Hearing aid user	0.4	0.4	2.2	1.5	0.4	0.3	-0.2	-0.8	0.2	-0.2	-0.4
Mother’s age at death	0.2	0.3	0.7	0.8	0.3	0.8	-0.3	-0.6	-0.3	-0.1	-0.1
Financial situation satisfaction	0.8	1.0	3.2	-1.0	0.1	-0.5	0.7	0.4	-1.2	-1.8	-1.4
Tinnitus: Yes, now most or all of the time	1.5	1.8	4.2	-0.4	-1.6	-0.3	1.3	2.0	-1.7	-1.2	-1.2
Commuting to job workplace: Public transport	1.2	1.4	2.8	0.3	-0.8	1.6	0.6	1.0	1.4	1.3	1.7
Eye problems/disorders: Glaucoma	0.2	0.2	0.8	-0.3	0.3	0.1	-0.2	0.2	0.9	-0.0	0.8
Medication: Blood pressure	0.5	1.0	3.3	0.4	0.1	1.8	1.4	1.4	-0.6	-0.0	-0.4
Pain type(s) experienced in last month: Hip pain	0.4	0.5	1.4	0.4	-0.1	-1.2	1.0	1.1	0.2	-0.0	-0.3
Supplements: Fish oil (including cod liver oil)	2.0	2.6	4.7	1.4	-0.9	1.9	1.4	1.0	1.9	2.2	1.8
High cholesterol (Self-reported)	0.6	1.1	2.9	0.0	-0.2	1.5	1.7	1.7	-0.2	-0.3	-0.7
Medication: Bendroflumethiazide	1.7	2.6	9.0	-3.0	-0.2	0.6	2.2	2.4	0.4	-0.3	0.4
Medication: Paracetamol	1.6	2.5	5.7	-1.6	-2.4	1.5	1.2	0.6	1.6	1.6	1.5
Medication: Lisinopril	3.5	4.5	11.4	-1.4	-0.8	2.5	3.4	3.3	1.2	0.7	1.7
Medication: Atorvastatin	0.5	0.7	3.2	1.1	1.8	0.3	-0.6	-0.1	-0.5	-0.3	-0.1
Illnesses of father: High blood pressure	0.6	0.7	1.8	-0.8	1.3	0.4	0.3	0.1	1.0	0.5	1.2
Alcohol drinker status: Never	1.1	1.3	4.3	0.4	0.1	-1.0	-0.3	-0.5	-1.7	-2.1	-1.2
Ever smoked	2.2	3.9	7.6	0.3	-2.4	1.4	2.4	2.4	-2.8	-0.9	-1.9
Basal metabolic rate	0.7	3.9	12.2	2.1	3.5	-1.5	-1.5	-0.8	2.2	1.8	1.0
Leg fat percentage (left)	1.5	5.5	21.1	3.6	4.6	-2.5	-1.8	-0.7	-0.4	-0.5	-0.1
Arm fat-free mass (left)	0.5	2.5	7.8	1.5	2.8	-1.2	-1.0	-0.4	2.0	1.5	0.9
Number of operations (self-reported)	0.5	0.8	1.9	1.4	0.5	0.4	-0.6	-0.7	-1.1	-1.1	-0.9
Average weekly beer plus cider intake	0.3	0.5	1.7	0.3	0.3	0.7	1.3	1.0	-0.2	0.8	0.0
Irritability	0.4	0.6	1.0	1.0	0.8	-0.3	-0.8	-0.9	0.6	0.7	1.0
Risk taking	0.1	0.2	0.7	-0.6	0.3	-0.8	0.1	-0.0	0.2	0.4	0.5
Ever had prostate specific antigen (PSA) test	0.5	0.5	3.2	0.3	-0.0	1.8	-0.3	-0.5	0.4	0.4	0.4
Fractured/broken bones in last 5 years	3.0	3.9	10.2	0.1	1.7	0.9	-3.2	-2.7	1.7	1.7	2.1
Age started oral contraceptive pill	0.9	1.1	6.2	0.9	0.6	2.5	-0.9	-0.0	-0.3	0.6	-0.2
Diastolic blood pressure, automated reading	0.9	2.7	9.3	0.9	3.1	0.8	-1.8	-1.1	1.7	1.1	1.4
Ever depressed for a whole week	1.3	1.6	4.3	-1.9	-2.1	-0.1	0.9	0.8	-0.5	-1.4	-1.1
Unable to work because of sickness or disability	1.2	1.5	4.7	1.1	0.0	-0.5	0.5	-0.1	-1.9	-2.2	-1.5
Commuting to job workplace: Cycle	0.3	0.3	0.6	-0.5	0.1	0.4	-0.7	-0.7	0.3	0.8	0.7
Myopia	1.1	1.6	4.0	1.6	0.6	1.1	0.6	0.5	1.3	1.4	2.0
Vascular/heart problems diagnosed by doctor	0.4	1.1	3.7	0.1	-1.7	-1.9	-0.5	-1.2	-0.8	-0.4	-0.4
Cholesterol lowering medication	0.4	0.6	1.7	1.3	0.8	0.1	0.7	1.3	-0.4	-0.4	-0.5
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	1.4	-0.4	1.2	0.6	0.9	0.7	0.9	0.3	0.5
Pain experienced in last month	0.4	0.7	1.9	0.7	1.4	0.8	-0.7	-1.1	-0.8	0.3	-0.3
Supplements: Calcium	0.8	0.9	1.9	0.2	-0.9	0.7	-1.0	-1.2	1.0	0.9	1.4
Basal cell carcinoma (self-reported)	0.6	0.7	1.7	0.9	1.3	0.5	-1.2	0.1	0.5	0.6	0.6
Heart attack/myocardial infarction (self-reported)	0.5	0.7	1.4	-0.2	1.1	-0.6	0.8	0.7	0.7	0.9	1.2
Deep venous thrombosis (DVT) (self-reported)	0.2	0.2	0.9	-0.1	0.9	-0.0	-0.2	0.3	0.8	0.0	0.1
Heart disease (siblings)	0.6	0.7	1.4	0.7	0.4	1.0	0.9	1.2	1.1	0.3	0.8
Alcohol drinker status: Previous	1.0	1.1	2.2	-0.7	-0.5	0.8	1.0	0.7	-1.4	-1.3	-1.5
Pack years of smoking	0.4	0.6	2.1	-0.1	-0.5	0.6	0.4	0.5	1.2	0.5	1.4
Impedance of whole body	0.2	0.9	4.2	0.7	-2.0	0.3	0.6	0.6	-1.1	-0.2	-0.4
Leg fat mass (left)	1.5	6.0	22.6	3.5	4.8	-2.8	-1.9	-0.8	0.7	0.3	0.4
Arm predicted mass (left)	0.6	2.9	8.9	1.6	3.0	-1.0	-0.9	-0.2	2.3	1.8	1.1