TWAS hub - DIDO1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1360	0.0310	1.7e-08	0.078	0.077	0.065	0.088	0.070	1.0e-09	1.2e-09	2.3e-08	7.3e-11	7.3e-09
2	GTEx	Adipose Subcutaneous	0.1520	0.0390	3.4e-06	0.091	NA	0.089	NA	0.121	7.2e-08	NA	9.0e-08	NA	4.1e-10
3	GTEx	Artery Aorta	0.1250	0.0460	2.7e-03	0.099	NA	0.112	NA	0.123	4.3e-06	NA	1.0e-06	NA	2.6e-07
4	GTEx	Cells Transformed fibroblasts	0.1270	0.0450	1.3e-03	0.055	NA	0.035	NA	0.035	5.7e-05	NA	1.2e-03	NA	1.1e-03
5	GTEx	Esophagus Muscularis	0.1330	0.0460	1.4e-03	0.050	NA	0.027	NA	0.052	5.0e-04	NA	8.4e-03	NA	4.3e-04
6	GTEx	Muscle Skeletal	0.0798	0.0297	3.6e-03	0.033	NA	0.044	NA	0.035	2.9e-04	NA	3.6e-05	NA	2.1e-04
7	GTEx	Nerve Tibial	0.1075	0.0360	8.4e-04	0.064	NA	0.070	NA	0.074	2.5e-05	NA	1.1e-05	NA	6.2e-06
8	GTEx	Skin Sun Exposed Lower leg	0.1200	0.0380	3.0e-04	0.063	NA	0.066	NA	0.061	6.7e-06	NA	3.5e-06	NA	9.1e-06
9	GTEx	Thyroid	0.1330	0.0350	9.0e-06	0.111	NA	0.119	NA	0.126	8.2e-09	NA	2.3e-09	NA	6.7e-10
10	METSIM	Adipose	0.1390	0.0302	4.3e-11	0.077	0.090	0.092	0.095	0.090	1.1e-11	2.3e-13	1.3e-13	4.3e-14	2.6e-13
11	YFS	Blood	0.0472	0.0104	2.8e-12	0.067	0.044	0.061	0.063	0.065	7.0e-21	2.3e-14	2.3e-19	1.0e-19	2.8e-20
12	TCGA	Brain Lower Grade Glioma	0.0627	0.0223	1.7e-06	0.089	0.066	0.079	NA	0.086	2.5e-10	5.2e-08	2.6e-09	NA	5.8e-10
13	TCGA	Lung Adenocarcinoma	0.0544	0.0236	1.2e-03	0.014	0.029	0.021	NA	0.015	7.1e-03	2.2e-04	1.4e-03	NA	6.2e-03
14	TCGA	Prostate Adenocarcinoma	0.0491	0.0211	8.5e-05	0.056	0.048	0.056	NA	0.059	1.5e-06	8.7e-06	1.5e-06	NA	9.3e-07
15	TCGA	Soft Tissue Sarcoma	0.1520	0.0660	3.9e-03	-0.005	0.030	0.008	NA	-0.004	8.7e-01	6.5e-03	9.7e-02	NA	7.0e-01
16	TCGA	Thyroid Carcinoma	0.0390	0.0200	3.8e-03	0.038	0.011	0.016	NA	0.031	1.3e-04	2.4e-02	8.9e-03	NA	4.8e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16
Ever used hormone-replacement therapy (HRT)	13.0	16.5	23.5	-3.6	-4.4	-3.5	-4.3	-4.3	-4.5	-4.2	-4.0	-4.3	-4.8	-4.0	-3.9	-3.5	-4.3	-3.0	-4.0
Medication for hormone replacement therapy	6.5	7.3	12.9	-1.8	-2.3	-3.6	-3.0	-2.8	-2.5	-2.1	-2.1	-2.7	-3.1	-3.0	-3.2	-2.7	-2.9	-0.6	-3.3
Number of full brothers	6.3	8.0	12.9	2.0	3.1	3.6	3.2	2.9	3.2	2.8	3.1	3.1	1.8	3.1	3.1	1.3	2.9	1.6	3.2
Had menopause	5.7	7.2	10.8	-1.8	-3.3	-2.1	-3.0	-2.6	-3.2	-2.7	-3.1	-2.6	-2.3	-2.8	-2.7	-2.6	-2.6	-2.3	-2.7
Medication: Levothyroxine sodium	5.6	9.5	14.6	-3.6	-3.6	-2.5	-2.9	-3.6	-3.4	-3.8	-3.2	-3.5	-2.8	-2.8	-2.7	-1.8	-2.7	-3.2	-2.7
Fasting Glucose	5.4	6.5	10.2	-2.3	-3.0	-2.2	-2.5	-2.7	-2.9	-2.5	-1.8	-2.8	-3.0	-2.6	-2.5	-2.3	-3.2	-1.7	-2.4
Father’s age at death	5.4	7.3	11.7	-2.3	-3.1	-2.8	-2.8	-2.5	-3.0	-2.7	-3.2	-2.6	-2.2	-2.6	-2.5	-2.9	-3.4	-1.2	-2.6
Heart disease (siblings)	5.0	6.1	8.7	2.6	2.4	2.0	2.7	2.6	2.6	2.5	1.7	2.9	3.0	2.6	2.6	1.9	2.6	1.4	2.7
Noisy workplace	4.2	5.2	12.6	-2.6	-2.1	-2.3	-2.0	-2.7	-2.0	-3.0	-3.5	-2.4	-2.1	-1.8	-1.9	-1.2	-2.6	-1.2	-2.0
Ulcerative Colitis (UC)	3.2	5.9	7.6	-1.5	-2.7	-2.0	-2.6	-2.4	-2.8	-2.8	-2.6	-2.6	-2.0	-2.5	-2.5	-2.7	-2.7	-1.4	-2.6
Loud music exposure frequency	2.9	3.2	5.5	-1.4	-1.6	-2.2	-1.9	-1.5	-1.5	-1.6	-1.5	-1.6	-2.0	-2.0	-2.0	-2.3	-2.0	-0.7	-2.0
Pack years adult smoking proportion	2.8	4.3	5.3	2.0	2.0	1.7	2.3	2.3	2.0	2.3	1.3	2.2	1.7	2.2	2.3	2.2	2.2	1.8	2.3
Tinnitus: Yes, but not now, but have in the past	2.7	2.9	8.8	-1.9	-1.6	-0.1	-1.6	-1.9	-1.6	-2.1	-1.1	-1.7	-1.9	-1.3	-1.3	-3.0	-2.2	-1.0	-1.3
Heel bone mineral density (BMD) T-score, automated (left)	2.6	5.8	8.9	1.8	2.5	2.5	2.7	3.0	2.4	2.6	2.4	2.8	1.3	2.7	2.7	1.2	2.8	0.4	2.8
Sitting height	2.6	18.6	30.0	-5.4	-4.5	-2.9	-4.3	-4.8	-4.3	-5.5	-3.5	-5.1	-4.7	-4.0	-4.0	-3.2	-4.0	-3.9	-4.0
Lung cancer (father)	2.6	3.0	6.2	1.8	2.5	0.6	1.9	1.3	2.4	1.8	1.4	1.9	1.6	1.7	1.5	2.1	1.9	0.9	1.6
Tinnitus: Yes, now most or all of the time	2.6	3.1	7.7	-2.8	-1.5	-1.4	-1.4	-2.0	-1.5	-1.6	-1.3	-2.0	-2.6	-1.6	-1.6	-1.3	-1.9	-0.7	-1.7
Medication: Seretide 50 evohaler	2.5	2.8	5.0	-1.9	-1.2	-1.8	-1.8	-1.5	-1.4	-1.0	-0.7	-1.6	-2.2	-2.0	-2.0	-2.2	-1.9	0.3	-2.0
Had major operations	2.5	2.9	8.0	2.2	1.9	0.7	1.8	1.5	2.0	1.6	1.2	1.7	0.8	1.6	1.6	1.7	1.4	2.8	1.6
Breast cancer (self-reported)	2.4	2.8	4.9	1.5	1.9	1.5	1.7	1.5	2.1	1.7	0.9	1.8	2.2	1.7	1.6	2.0	1.8	1.1	1.6
Medication: Atorvastatin	2.4	3.0	8.9	-0.7	-1.9	-0.7	-1.6	-1.6	-1.8	-1.9	-2.1	-1.7	-1.7	-1.6	-1.6	-1.4	-1.6	-3.0	-1.5
Pack years of smoking	2.4	3.5	4.7	1.6	1.8	1.8	2.2	2.0	1.7	2.0	1.1	1.9	1.4	2.1	2.2	2.0	2.0	1.5	2.2
Type 2 Diabetes (T2D) (2018)	2.2	4.2	14.1	1.0	2.1	1.8	2.2	1.6	2.1	1.6	1.0	1.9	2.1	2.2	2.1	3.8	2.0	1.8	2.1
Chronotype (morning person)	2.2	5.1	9.6	0.9	2.8	2.6	2.6	2.1	2.8	2.1	3.1	2.2	2.0	2.4	2.4	1.2	2.2	0.7	2.4
Forced vital capacity (FVC)	2.2	8.6	11.3	-2.7	-2.9	-3.2	-3.2	-3.1	-2.8	-3.3	-2.8	-3.4	-2.9	-3.0	-3.1	-2.7	-3.0	-0.8	-3.1
Illnesses of father: None of the above (group 1)	2.2	2.7	5.0	0.5	1.9	1.4	1.8	1.3	1.6	1.6	1.2	1.3	1.6	2.0	2.0	2.1	2.2	-0.4	2.1
Eye problems/disorders: Diabetes related eye disease	2.1	2.3	5.7	1.0	1.5	1.1	1.6	0.9	1.6	0.7	0.9	1.2	2.4	1.8	1.8	2.3	1.9	-0.1	1.8
Medication: Metformin	2.1	3.0	8.2	1.2	1.6	2.0	1.8	1.5	1.8	1.3	0.9	1.6	2.4	1.7	1.6	2.9	1.9	1.0	1.6
Ever unenthusiastic/disinterested for a whole week	2.1	2.5	5.5	-1.1	-1.6	-1.6	-1.5	-1.7	-1.4	-1.9	-2.3	-1.8	-1.6	-1.6	-1.6	-0.2	-1.7	-0.5	-1.7
Medication: Gliclazide	2.1	2.3	7.0	1.1	1.5	1.4	1.7	1.5	1.6	1.3	0.3	1.5	1.3	1.6	1.5	2.6	1.7	1.4	1.5
Mean Putamen Volume	2.0	2.3	4.1	0.3	1.7	2.0	1.7	1.5	1.6	1.6	1.5	1.8	0.7	1.5	1.6	1.3	1.5	1.6	1.6
Hand grip strength (left)	2.0	5.4	9.2	-2.9	-1.9	-2.1	-2.7	-2.0	-2.2	-1.4	-0.2	-2.2	-2.2	-2.8	-3.0	-3.0	-2.4	0.2	-3.0
Illnesses of father: High blood pressure	2.0	2.4	4.4	-1.2	-1.6	-1.4	-1.7	-1.7	-1.4	-1.8	-1.0	-1.6	-1.5	-1.7	-1.7	-1.7	-2.1	0.6	-1.8
Heel bone mineral density (BMD) T-score, automated (right)	1.9	4.3	7.8	1.9	1.9	2.0	2.1	2.8	1.9	2.3	2.3	2.4	1.6	2.3	2.3	1.0	2.4	0.6	2.4
Hair/balding pattern: Pattern 4	1.9	4.5	7.3	-2.0	-2.7	-1.3	-2.2	-2.1	-2.7	-2.6	-2.7	-2.2	-2.4	-1.9	-1.8	-1.3	-2.3	-1.0	-1.8
Leg fat percentage (right)	1.9	6.8	15.1	1.2	2.3	3.9	3.0	2.3	2.6	1.9	3.3	2.3	2.2	2.8	2.9	2.2	2.9	-1.8	2.9
Forced expiratory volume in 1-second (FEV1), predicted	1.9	3.9	5.6	-2.1	-2.2	-2.0	-2.2	-1.7	-2.1	-1.9	-1.5	-2.0	-2.4	-2.2	-2.2	-2.0	-2.0	-0.1	-2.1
Medication: Lisinopril	1.9	2.5	4.3	1.5	1.6	1.3	1.7	1.6	1.5	1.7	1.0	1.8	2.1	1.7	1.8	1.0	1.5	0.9	1.8
Leg fat percentage (left)	1.9	6.9	16.3	1.1	2.3	4.0	2.9	2.5	2.5	2.0	3.3	2.4	2.1	2.8	2.9	2.1	3.0	-1.8	2.9
Glaucoma (self-reported)	1.8	2.1	4.2	0.8	1.9	2.1	1.7	1.5	1.7	1.2	1.8	1.4	0.5	1.6	1.6	0.7	1.6	-0.8	1.5
Friendships satisfaction	1.8	2.2	4.5	0.9	1.6	2.1	1.3	1.5	1.4	1.4	0.8	1.2	2.0	1.5	1.4	1.8	1.8	0.6	1.4
Osteoporosis (self-reported)	1.8	2.2	5.1	-0.9	-1.6	-1.6	-1.4	-1.3	-1.5	-1.4	-1.4	-1.3	-2.3	-1.4	-1.4	-1.9	-1.9	-0.5	-1.5
Ulcerative Colitis	1.7	2.5	4.8	-1.2	-1.9	-1.1	-1.8	-1.3	-1.9	-1.6	-1.5	-1.7	-0.5	-1.6	-1.6	-2.2	-1.6	-1.5	-1.6
Forced vital capacity (FVC), Best measure	1.7	6.1	9.9	-2.0	-2.1	-3.1	-2.8	-2.9	-2.1	-2.7	-2.1	-2.9	-2.0	-2.8	-2.9	-1.7	-2.3	-1.0	-2.9
Handedness (chirality/laterality): Left-handed	1.7	2.1	3.7	0.1	1.3	1.9	1.6	1.9	1.3	1.7	1.8	1.6	0.4	1.5	1.6	0.7	1.8	0.0	1.5
Eye problems/disorders: Glaucoma	1.7	2.1	5.4	0.5	1.8	2.3	1.7	1.4	1.7	1.1	1.7	1.3	0.8	1.7	1.6	0.9	1.4	-0.1	1.5
Breast Cancer	1.6	4.0	6.4	-0.8	-2.4	-1.2	-2.2	-2.0	-2.3	-2.4	-2.1	-2.3	-1.8	-2.2	-2.0	-0.5	-1.8	-2.5	-2.1
Other serious medical condition/disability diagnosed by doctor	1.6	2.0	5.7	-1.9	-1.8	-0.3	-1.0	-1.9	-1.7	-2.4	-1.7	-1.8	-0.9	-0.8	-0.7	0.7	-1.4	-1.3	-0.7
Relative age voice broke	1.6	2.4	5.8	-0.4	-1.7	-1.4	-1.6	-1.4	-1.7	-1.3	-0.9	-1.6	-2.4	-1.7	-1.5	-1.6	-1.8	-1.4	-1.5
Age when periods started (menarche)	1.6	3.8	14.2	-0.8	-2.2	-1.6	-1.6	-2.1	-2.0	-2.2	-3.8	-2.1	-2.5	-1.5	-1.5	-0.9	-2.1	0.4	-1.5
Standing height	1.6	15.6	31.5	-5.0	-4.5	-2.3	-3.7	-4.6	-4.2	-5.6	-3.3	-4.9	-4.0	-3.3	-3.2	-2.4	-3.5	-3.8	-3.2
Medication for cholesterol	1.6	2.4	7.6	1.7	1.8	0.8	1.5	1.4	1.8	1.4	0.7	1.4	1.4	1.4	1.4	2.8	1.4	1.4	1.4
Intelligence (Savage-Jansen 2018)	1.5	4.5	6.8	1.8	2.5	2.5	2.1	2.0	2.5	2.5	2.4	2.0	2.0	2.2	2.0	1.1	2.6	0.6	2.0
Verbal and Numeric Reasoning (VNR)	1.5	3.5	7.2	2.7	1.9	1.9	1.6	2.3	1.9	2.5	1.6	1.9	2.1	1.6	1.5	-0.0	1.9	1.6	1.5
Heel T-Score	1.5	12.2	22.1	3.0	4.2	3.4	3.5	3.6	4.0	3.8	4.7	3.8	3.4	3.5	3.4	2.1	3.5	0.1	3.5
Forced expiratory volume in 1-second (FEV1)	1.5	4.9	6.7	-2.3	-2.1	-2.3	-2.6	-2.1	-2.1	-2.3	-1.7	-2.5	-2.2	-2.3	-2.4	-2.5	-2.0	-1.4	-2.4
Hypothyroidism/myxoedema (self-reported)	1.5	2.9	9.0	-3.0	-1.8	-0.7	-1.4	-2.2	-1.7	-2.3	-1.6	-2.1	-1.1	-1.1	-1.1	-0.4	-1.2	-2.2	-1.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.5	1.8	5.8	-1.0	-1.3	-0.7	-1.2	-0.9	-1.4	-1.0	0.4	-1.1	-2.2	-1.2	-1.3	-2.4	-1.2	-1.4	-1.3
Number of operations (self-reported)	1.5	2.2	4.9	2.2	1.5	1.6	1.5	1.4	1.5	1.3	1.1	1.6	1.1	1.6	1.5	0.8	1.0	1.9	1.5
Frequency of depressed mood in last 2 weeks	1.4	2.0	5.7	0.7	1.1	2.4	1.2	1.6	1.1	1.3	0.9	1.2	1.0	1.4	1.5	2.3	1.5	-0.2	1.5
Neck or shoulder pain in last month	1.4	1.9	3.9	-0.1	-1.8	-1.9	-1.5	-1.2	-1.9	-1.2	-2.0	-1.1	-1.7	-1.5	-1.4	-0.0	-1.2	0.2	-1.4
Loneliness, isolation	1.4	1.9	9.3	-1.2	-1.7	0.3	-1.4	-1.0	-1.7	-1.5	-0.3	-1.6	-1.5	-1.1	-1.0	-0.5	-0.9	-3.0	-1.1
Commuting to job workplace: Cycle	1.4	1.7	2.5	-1.3	-1.4	-0.8	-1.4	-1.5	-1.3	-1.4	-0.6	-1.6	-1.5	-1.4	-1.4	-1.0	-1.3	-0.9	-1.5
Basal cell carcinoma (self-reported)	1.4	1.7	3.5	-0.8	-1.1	-1.4	-1.4	-1.8	-0.9	-1.8	-1.9	-1.6	-0.6	-1.4	-1.4	-0.1	-1.4	0.2	-1.4
Alcohol drinker status: Previous	1.4	1.6	5.0	-0.5	-1.8	-1.0	-1.2	-1.1	-1.6	-1.6	-2.2	-1.2	-0.8	-1.0	-0.9	-1.0	-1.3	-0.5	-0.9
Serious illness, injury or assault to yourself	1.3	1.6	3.6	0.0	1.4	1.8	1.5	0.9	1.3	1.0	0.9	1.0	0.2	1.3	1.3	1.9	0.6	1.6	1.4
Chronic bronchitis/emphysema (father)	1.3	1.5	3.7	-0.4	-1.2	-1.3	-1.6	-1.0	-1.2	-0.7	-0.2	-1.2	-0.7	-1.8	-1.9	-0.3	-1.1	-1.1	-1.9
Pulse rate	1.3	2.2	3.6	-0.9	-1.7	-1.1	-1.7	-1.2	-1.9	-1.3	-0.9	-1.7	-1.6	-1.5	-1.5	-1.4	-1.9	-1.2	-1.5
Schizophrenia (2014)	1.2	2.7	8.5	-0.5	-1.9	-0.7	-1.9	-0.6	-1.9	-0.9	-1.1	-1.5	-2.9	-1.9	-1.7	-2.3	-1.4	-1.3	-1.7
Height	1.2	24.0	54.8	-6.7	-5.2	-2.7	-4.0	-6.1	-4.8	-7.4	-4.2	-6.0	-4.7	-3.7	-3.6	-2.3	-4.0	-6.2	-3.6
Lung FEV1/FVC ratio	1.2	6.2	12.0	1.3	2.9	2.2	2.6	2.7	2.6	2.6	2.3	2.6	2.3	2.9	2.6	1.7	3.5	-1.4	2.6
Severe depression (siblings)	1.2	1.3	4.3	0.5	1.0	2.1	1.2	1.4	1.2	0.9	0.9	1.2	1.2	1.2	1.3	-0.2	0.7	0.7	1.3
Waist circumference	1.2	4.5	13.0	-0.0	1.9	3.6	2.0	1.6	2.0	1.3	3.4	1.3	2.3	1.8	1.9	1.2	2.2	-2.8	1.8
Hair/balding pattern: Pattern 2	1.2	1.5	3.0	1.0	1.2	1.5	1.2	1.2	1.2	1.0	1.7	1.3	1.3	1.1	1.1	1.1	0.8	1.5	1.0
Number of live births	1.2	1.6	3.7	0.6	1.6	1.9	1.4	1.3	1.6	1.5	1.3	1.3	0.4	1.3	1.5	0.6	1.0	0.1	1.5
Wheeze or whistling in the chest in last year	1.2	2.2	5.6	-0.7	-1.4	-1.6	-1.4	-1.7	-1.6	-1.6	-2.4	-1.6	-1.5	-1.6	-1.6	0.2	-1.6	0.2	-1.6
Diabetes diagnosed by doctor	1.2	1.9	14.9	0.2	1.0	1.4	1.4	0.3	1.1	0.2	0.1	0.7	1.4	1.3	1.4	3.9	1.4	0.2	1.4
Medication: Omeprazole (e.g. Zanprol)	1.2	1.4	2.6	-0.7	-1.6	-1.3	-1.3	-1.4	-1.4	-1.2	-0.8	-1.3	-1.6	-1.2	-1.2	-0.3	-1.2	-0.4	-1.2
Lupus	1.1	1.7	3.0	-0.6	-1.0	-1.7	-1.4	-1.5	-1.1	-1.0	-1.0	-1.3	-1.6	-1.5	-1.6	-1.1	-1.2	-0.7	-1.6
Hypothyroidism (self reported)	1.1	2.5	7.8	-2.2	-1.8	-0.2	-1.3	-2.0	-1.8	-2.3	-1.3	-2.0	-0.9	-0.9	-0.9	0.2	-1.0	-2.8	-0.9
Medication: Atenolol	1.1	1.4	5.1	0.4	0.6	2.3	1.2	0.9	0.7	0.4	1.2	0.8	-0.3	1.4	1.4	0.0	1.3	-2.2	1.3
Hearing difficulty/problems with background noise	1.1	1.7	3.8	-1.9	-1.1	-0.7	-1.1	-1.3	-1.0	-1.5	-1.5	-1.3	-1.8	-1.3	-1.2	-0.7	-1.0	-1.7	-1.3
Breastfed as a baby	1.1	1.4	2.8	-1.7	-1.4	-0.2	-1.1	-1.2	-1.4	-1.5	-1.6	-1.4	-0.8	-0.9	-0.9	-1.1	-0.9	-1.3	-0.9
Suffer from ‘nerves’	1.1	1.7	3.0	-1.7	-1.1	-1.4	-1.3	-1.5	-1.0	-1.4	-1.0	-1.3	-1.7	-1.4	-1.5	-0.2	-1.1	-0.7	-1.5
Supplements: Vitamin C	1.1	1.3	2.0	0.4	1.4	0.7	1.4	1.2	1.4	1.2	1.4	1.3	0.4	1.3	1.2	0.8	1.1	0.4	1.3
Depressed Affect (Nagel 2018)	1.0	2.1	4.9	-2.1	-1.7	-0.3	-1.4	-1.6	-1.7	-2.1	-1.2	-1.5	-0.9	-1.0	-1.1	-0.3	-1.2	-2.2	-1.1
Hayfever, allergic rhinitis or eczema	1.0	2.1	4.2	0.4	1.4	1.8	1.7	1.8	1.5	1.7	1.8	1.4	0.6	1.5	1.5	0.8	2.1	0.2	1.4
Body mass index (BMI)	1.0	4.2	12.5	-0.4	1.7	3.5	1.8	1.6	1.8	1.5	3.5	1.3	2.5	1.6	1.7	1.3	2.1	-2.4	1.7
Medication: Ramipril	1.0	1.3	2.6	-1.5	-1.6	-0.4	-1.0	-1.2	-1.4	-1.4	-1.2	-1.3	-1.0	-1.0	-0.8	-0.4	-1.2	-1.1	-0.8
Trunk fat-free mass	1.0	5.6	17.8	-4.2	-2.2	0.3	-2.1	-2.4	-2.0	-2.9	0.1	-3.0	-1.1	-2.0	-1.9	-1.9	-1.7	-4.0	-2.0
Depression (self-reported)	1.0	1.1	2.2	-0.7	-1.2	-1.5	-1.2	-1.1	-1.1	-0.9	-1.4	-1.1	-1.2	-1.1	-1.1	-0.3	-1.1	0.4	-1.1
Medication: Lansoprazole	1.0	1.1	2.3	1.1	0.9	0.6	1.2	0.9	0.9	0.7	0.4	1.2	0.8	1.5	1.5	1.1	1.0	0.9	1.5
Trunk predicted mass	1.0	5.5	17.4	-4.2	-2.1	0.2	-2.1	-2.4	-2.0	-2.8	0.1	-2.9	-1.0	-1.9	-1.9	-1.9	-1.6	-4.0	-1.9
Prostate Cancer	0.9	1.3	2.3	1.1	1.1	1.2	1.3	0.7	1.2	0.9	1.5	1.0	1.2	1.2	1.2	1.3	1.4	-0.5	1.2
HDL Cholesterol	0.9	1.5	3.4	-0.3	-1.0	-1.8	-1.5	-1.1	-1.1	-0.7	-1.5	-1.2	-1.0	-1.6	-1.6	-0.6	-1.3	0.5	-1.6
Diabetes (self-reported)	0.9	1.4	9.9	0.3	1.0	1.1	1.3	0.4	1.2	0.2	-0.1	0.7	1.1	1.2	1.2	3.1	1.2	0.1	1.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.9	3.0	4.9	-1.8	-1.2	-2.2	-2.1	-1.9	-1.3	-1.7	-0.8	-2.1	-1.4	-2.0	-2.2	-1.6	-1.4	-1.2	-2.2
Arm fat-free mass (right)	0.9	4.8	17.1	-3.7	-2.0	0.6	-1.9	-2.2	-1.9	-2.6	0.4	-2.7	-0.9	-1.8	-1.7	-1.6	-1.4	-4.1	-1.7
Exposure to tobacco smoke outside home	0.9	1.2	1.6	-1.1	-1.1	-1.1	-1.2	-1.2	-1.2	-1.2	-1.2	-1.3	-1.1	-0.9	-0.9	0.2	-1.0	-1.2	-0.9
Age at first live birth	0.9	1.5	4.0	0.6	-1.1	-1.7	-1.4	-0.4	-1.2	-0.3	-2.0	-0.5	-0.6	-1.2	-1.3	-1.2	-1.2	2.0	-1.2
Arm predicted mass (right)	0.9	4.6	14.6	-3.7	-2.0	0.5	-1.9	-2.2	-1.9	-2.7	0.3	-2.7	-1.1	-1.8	-1.7	-1.6	-1.5	-3.8	-1.8
Commuting to job workplace: Walk	0.9	1.0	3.2	0.8	0.8	1.5	0.8	1.2	0.7	1.2	0.7	1.1	1.8	0.9	0.9	0.5	1.0	0.3	0.9
Whole body water mass	0.9	5.2	18.0	-4.2	-2.0	0.6	-2.0	-2.2	-1.9	-2.7	0.4	-2.8	-0.9	-1.8	-1.8	-1.8	-1.5	-4.0	-1.8
Arm fat-free mass (left)	0.9	4.4	16.9	-4.0	-1.9	0.9	-1.6	-2.0	-1.7	-2.5	0.7	-2.5	-0.8	-1.5	-1.5	-1.5	-1.3	-4.1	-1.5
Risk taking	0.9	1.3	4.1	-1.6	-0.4	-0.6	-1.1	-0.7	-0.6	-0.2	0.9	-1.0	-1.1	-1.1	-1.2	-2.0	-0.8	-1.9	-1.3
Supplements: Calcium	0.9	1.0	2.0	-1.2	-0.6	-1.0	-0.8	-1.2	-0.5	-1.2	-0.6	-1.0	-1.4	-1.0	-1.1	-0.3	-0.7	-1.3	-1.1
Blood Eosinophil Count	0.8	6.4	13.9	0.7	2.4	3.7	3.1	1.8	2.5	1.2	2.0	2.0	2.6	3.2	3.3	3.1	2.5	0.7	3.3
Allergy or Eczema	0.8	2.1	3.8	0.2	1.4	1.7	1.7	1.9	1.5	1.7	1.2	1.5	0.5	1.5	1.5	1.3	2.0	0.7	1.5
Lung FVC	0.8	4.0	12.0	0.4	-1.5	-3.5	-2.4	-1.6	-1.7	-1.3	-2.5	-1.7	-1.1	-2.3	-2.4	-2.2	-2.1	0.4	-2.3
Maternal smoking around birth	0.8	1.2	2.5	-0.3	-1.1	-1.4	-1.2	-1.2	-1.0	-1.1	-1.6	-1.2	-1.1	-1.2	-1.2	-0.4	-0.8	0.2	-1.3
Nervous feelings	0.8	1.5	3.3	-1.0	-1.3	-1.0	-1.1	-1.4	-1.1	-1.6	-1.8	-1.3	-1.6	-1.1	-1.0	0.3	-1.4	-0.8	-1.0
Chronic bronchitis/emphysema (mother)	0.8	1.0	1.6	0.2	1.2	1.3	1.1	0.9	1.1	0.7	-0.2	0.8	1.2	1.2	1.2	0.8	1.0	0.6	1.2
Comparative body size at age 10	0.8	2.2	14.3	0.9	1.2	2.1	0.9	1.3	1.2	1.2	0.7	1.1	3.8	1.0	1.0	1.2	1.7	0.0	1.0
Leg fat mass (right)	0.8	3.1	11.0	-0.3	1.1	3.3	1.6	1.1	1.3	0.6	2.6	0.9	1.7	1.6	1.7	1.4	1.8	-2.6	1.7
Overall health rating	0.8	1.7	6.3	1.4	1.1	1.5	1.4	1.0	1.2	1.0	1.0	1.2	0.5	1.1	1.2	2.5	1.5	-0.6	1.2
Age at last live birth	0.8	1.2	3.8	-0.4	-1.0	-0.9	-1.4	-0.5	-1.1	-0.4	-1.5	-0.8	-0.9	-1.2	-1.2	-1.9	-1.3	0.7	-1.2
Whole body fat-free mass	0.8	4.8	17.1	-4.1	-1.9	0.6	-1.9	-2.2	-1.8	-2.6	0.5	-2.7	-0.8	-1.8	-1.7	-1.7	-1.4	-3.9	-1.8
Miserableness	0.8	1.4	5.1	-1.3	-1.0	-0.6	-1.1	-1.3	-0.9	-1.4	-0.8	-1.2	-0.7	-1.2	-1.2	0.5	-0.9	-2.3	-1.2
Leg fat mass (left)	0.8	3.1	11.7	-0.4	1.1	3.4	1.6	1.2	1.3	0.6	2.5	0.9	1.6	1.6	1.7	1.4	1.8	-2.7	1.7
Worry (Nagel 2018)	0.7	1.4	2.7	-1.6	-1.1	-0.8	-1.1	-1.6	-1.0	-1.5	-0.9	-1.3	-1.6	-1.0	-0.9	-0.5	-1.1	-1.1	-1.0
Triglycerides	0.7	1.2	2.5	0.2	1.0	1.6	1.3	1.1	1.0	0.8	1.0	1.1	0.7	1.4	1.5	1.1	0.9	0.1	1.4
Sensitivity / hurt feelings	0.7	1.2	3.7	-0.2	1.0	1.3	1.1	0.5	1.2	0.4	0.9	0.6	1.3	1.1	1.1	1.9	1.5	-1.0	1.1
Diabetes (mother)	0.7	0.9	3.1	-0.4	0.4	1.8	0.8	0.4	0.6	0.1	1.5	0.5	1.2	0.9	0.9	1.0	1.0	-1.0	1.0
Leg predicted mass (left)	0.7	3.5	14.6	-3.8	-1.5	0.9	-1.4	-1.8	-1.3	-2.2	0.9	-2.3	-0.5	-1.4	-1.3	-1.1	-1.1	-3.5	-1.4
Qualifications: None of the above	0.7	1.5	2.8	-0.8	-1.2	-1.7	-1.1	-1.5	-1.2	-1.5	-1.5	-1.1	-1.7	-1.2	-1.2	-0.2	-1.2	-0.6	-1.2
Financial difficulties in last 2 years	0.7	1.0	3.6	-0.2	0.9	0.9	0.7	0.2	0.9	0.5	1.3	0.3	1.3	0.8	0.8	1.9	1.3	-1.3	0.8
Fluid intelligence score	0.7	1.4	5.3	2.3	1.2	0.3	0.7	1.1	1.2	1.6	0.2	1.1	1.6	0.7	0.7	0.5	1.0	2.1	0.6
Arm fat percentage (right)	0.7	2.7	6.7	-0.7	1.2	2.6	1.6	0.9	1.4	0.8	2.4	0.9	1.7	1.5	1.6	1.5	1.7	-2.6	1.6
Frequency of tiredness / lethargy in last 2 weeks	0.7	1.1	3.3	1.2	0.6	1.5	0.9	1.0	0.7	0.8	1.0	1.1	0.7	1.0	0.9	1.8	1.0	1.0	0.9
Body fat percentage	0.7	2.8	8.3	-0.2	1.0	2.9	1.7	1.1	1.2	0.6	2.0	1.0	1.3	1.7	1.8	1.8	1.9	-2.5	1.9
Number of children fathered	0.7	0.7	1.7	-0.1	0.7	1.3	1.0	0.9	0.6	1.0	1.0	0.8	0.4	1.0	0.9	-1.0	0.5	0.8	1.0
Medication: Allopurinol	0.7	0.9	1.9	-0.8	-0.5	-0.6	-1.0	-1.1	-0.7	-0.7	0.1	-1.0	-1.1	-1.3	-1.4	-0.3	-0.7	-1.1	-1.3
Chest pain or discomfort	0.7	1.0	2.0	0.0	-1.0	-0.9	-1.1	-0.9	-1.0	-0.7	-0.4	-0.8	-1.4	-1.3	-1.3	-1.1	-1.1	-0.9	-1.3
Medication: Aspirin	0.7	0.9	1.7	-1.2	-1.0	-0.7	-0.8	-1.3	-1.0	-1.3	-1.2	-0.9	-1.0	-0.7	-0.7	-1.0	-1.1	0.1	-0.8
Leg fat-free mass (right)	0.7	3.6	15.3	-3.9	-1.6	0.8	-1.5	-1.7	-1.4	-2.1	0.8	-2.2	-0.6	-1.5	-1.4	-1.4	-1.1	-3.5	-1.5
Arm fat percentage (left)	0.7	2.9	7.5	-0.6	1.3	2.7	1.6	1.0	1.5	0.8	2.5	1.0	1.6	1.5	1.7	1.7	1.8	-2.4	1.7
Qualifications: nursing, teaching	0.7	1.2	6.8	0.7	1.2	0.2	0.6	0.8	1.2	1.1	0.7	0.9	2.6	0.5	0.4	1.7	1.2	-0.1	0.3
Leg predicted mass (right)	0.7	3.7	15.7	-4.0	-1.6	0.8	-1.5	-1.7	-1.4	-2.1	0.8	-2.2	-0.6	-1.5	-1.5	-1.4	-1.2	-3.5	-1.5
Hearing aid user	0.7	0.8	10.5	-0.5	-0.3	0.4	0.1	-0.5	-0.1	-0.8	-0.3	-0.5	-0.9	0.2	0.2	0.3	0.3	-3.2	0.1
Medication: Bendroflumethiazide	0.7	1.0	4.0	-1.3	-1.2	-0.4	-0.9	-0.9	-1.3	-0.8	-0.0	-0.8	0.8	-0.8	-0.7	-1.3	-0.4	-2.0	-0.7
Basal metabolic rate	0.7	3.7	15.4	-3.8	-1.6	1.0	-1.4	-1.8	-1.4	-2.3	0.8	-2.3	-0.5	-1.3	-1.3	-1.2	-1.0	-3.9	-1.3
Diastolic blood pressure, automated reading	0.7	2.0	4.5	0.0	1.1	1.9	2.0	1.3	1.3	1.2	0.8	1.6	0.1	1.8	2.1	0.6	1.0	1.5	2.1
Ever depressed for a whole week	0.7	0.8	1.6	-1.0	-0.9	-1.3	-0.8	-0.8	-0.7	-1.1	-1.2	-0.7	-0.9	-1.0	-0.9	0.1	-1.1	0.5	-0.9
Unable to work because of sickness or disability	0.7	0.9	7.1	0.3	0.8	0.7	0.5	0.3	0.8	0.7	1.4	0.6	-0.1	0.4	0.4	2.7	0.5	0.7	0.4
Arm predicted mass (left)	0.7	3.6	16.5	-3.6	-1.6	1.0	-1.4	-1.6	-1.5	-2.1	0.8	-2.2	-0.4	-1.3	-1.3	-1.4	-1.0	-4.1	-1.3
Diabetes (father)	0.6	0.7	2.5	-0.2	-1.3	-0.6	-0.7	-0.8	-1.1	-1.3	-1.6	-0.8	-0.3	-0.4	-0.4	-0.9	-0.7	-0.8	-0.4
Leg fat-free mass (left)	0.6	3.4	14.5	-3.8	-1.4	0.9	-1.3	-1.8	-1.2	-2.1	0.9	-2.2	-0.4	-1.3	-1.3	-1.1	-1.0	-3.5	-1.3
Hand grip strength (right)	0.6	1.7	5.3	-2.3	-1.0	-0.5	-1.4	-1.1	-1.2	-0.7	0.1	-1.3	-0.9	-1.4	-1.5	-1.9	-1.1	1.0	-1.6
Bilateral oophorectomy (both ovaries removed)	0.6	0.7	1.9	-0.9	-0.2	-1.0	-0.4	-1.2	-0.2	-1.1	-0.8	-0.7	-1.4	-0.4	-0.6	0.8	-0.8	1.0	-0.6
Pain all over the body in last month	0.6	0.7	2.0	0.2	0.6	0.8	0.8	0.3	0.7	0.1	1.4	0.7	-0.4	0.9	0.9	0.9	0.3	1.4	1.0
Neuroticism score	0.6	1.2	3.8	-1.7	-1.2	0.2	-0.9	-1.2	-1.0	-1.7	-0.9	-1.2	-0.9	-0.7	-0.7	0.6	-0.5	-1.9	-0.8
Hip circumference	0.6	2.7	14.5	-1.4	0.5	3.2	1.1	0.5	0.8	-0.1	2.5	0.1	1.3	1.0	1.1	0.5	1.5	-3.8	1.1
Length of working week for main job	0.6	0.6	3.4	1.8	0.7	0.6	-0.0	0.9	0.6	1.5	0.8	0.8	0.9	-0.2	-0.3	-0.4	0.3	0.2	-0.3
High blood pressure (siblings)	0.6	0.8	1.4	-0.9	-1.1	-0.9	-0.8	-0.7	-0.9	-1.0	-0.9	-0.7	-0.7	-1.0	-0.9	-1.1	-1.2	0.1	-0.9
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.8	2.8	-0.7	-1.0	-0.5	-0.8	-0.9	-0.9	-1.2	-0.5	-1.0	-0.7	-0.7	-0.6	0.5	-1.0	-1.7	-0.6
Emphysema/chronic bronchitis	0.6	0.7	2.4	-1.0	-0.6	-0.7	-0.6	-1.0	-0.9	-1.0	-1.2	-0.8	-1.6	-0.6	-0.4	0.1	-1.1	0.1	-0.4
Guilty feelings	0.6	0.9	4.4	-0.6	0.9	2.1	1.0	0.6	1.0	0.3	1.5	0.4	-0.3	0.9	0.8	0.4	1.2	-0.6	0.8
Mother’s age at death	0.6	0.7	2.6	0.3	0.0	1.2	0.7	1.3	0.2	0.8	0.7	1.0	0.3	1.0	1.0	-0.7	0.5	1.6	1.0
Ever smoked	0.6	1.0	3.6	-1.4	-0.9	-0.7	-0.9	-0.8	-1.0	-0.7	0.2	-1.1	-1.9	-0.9	-0.8	-0.6	-1.4	-0.6	-0.9
Age started oral contraceptive pill	0.6	0.7	2.1	-0.4	-0.7	-0.9	-0.8	-1.3	-0.6	-1.0	-0.7	-1.1	0.2	-0.8	-0.7	-0.6	-0.9	-1.4	-0.7
Myopia	0.6	0.9	3.1	-1.8	-1.4	0.2	-0.6	-0.7	-1.2	-1.3	0.2	-0.9	0.0	-0.3	-0.2	-1.5	-0.5	-1.4	-0.3
Alzheimer’s Disease (in father)	0.5	0.6	1.9	0.6	1.0	0.1	0.6	0.8	1.0	0.7	0.3	0.9	0.8	0.5	0.5	1.1	0.5	1.4	0.5
Irritable Bowel Disease (IBD)	0.5	1.3	3.8	-0.0	-1.4	-1.3	-1.1	-0.6	-1.4	-1.0	-1.3	-0.9	-1.4	-0.9	-1.0	-2.0	-1.3	0.3	-1.0
Age at First Birth	0.5	0.7	3.7	0.4	-1.2	-0.6	-1.1	-0.1	-1.1	-0.1	-1.2	-0.3	0.3	-0.7	-0.7	-1.9	-0.7	0.5	-0.7
Body Mass Index (BMI) (2010)	0.5	0.6	3.1	0.5	0.3	1.8	0.6	0.9	0.3	0.7	1.1	0.4	-0.1	0.6	0.7	-0.6	1.0	-0.9	0.7
BMI	0.5	3.0	11.3	-0.1	1.7	3.1	1.3	1.5	1.8	1.5	3.4	1.2	2.1	1.1	1.0	0.7	1.6	-1.9	1.0
Supplements: Zinc	0.5	0.5	4.0	-2.0	-0.3	0.2	-0.0	-0.5	-0.2	-0.9	0.1	-0.5	-1.1	0.0	0.0	-0.7	0.1	-1.0	0.0
High blood pressure (mother)	0.5	0.8	1.7	-1.0	-1.0	-1.0	-0.7	-1.0	-0.9	-1.3	-1.2	-1.1	-0.1	-0.7	-0.7	-0.4	-0.7	-0.7	-0.7
Illnesses of siblings	0.5	0.7	1.5	-0.6	-0.3	-1.0	-1.0	-0.8	-0.5	-0.2	0.1	-1.1	-1.2	-1.1	-1.1	-0.4	-0.5	-1.0	-1.1
Time employed in main current job	0.5	0.6	2.4	1.2	-0.5	-0.6	-0.8	0.0	-0.7	0.4	-0.5	0.1	-0.6	-0.7	-0.7	-1.5	-0.7	0.9	-0.6
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.5	1.3	-1.0	-0.6	-0.3	-0.4	-1.0	-0.6	-1.0	-0.8	-0.9	-0.8	-0.5	-0.6	0.4	-0.3	-1.1	-0.5
Arm fat mass (right)	0.5	2.0	12.0	-1.8	0.4	2.4	0.8	0.1	0.6	-0.2	2.1	-0.1	1.1	0.7	0.8	0.9	1.0	-3.5	0.8
Exposure to tobacco smoke at home	0.5	0.5	2.0	-0.5	0.7	1.4	0.6	0.6	0.6	0.7	1.3	0.6	0.2	0.6	0.6	0.7	0.5	-0.5	0.6
Pulse wave reflection index	0.5	0.7	2.2	-0.2	0.6	0.6	1.2	0.6	0.8	0.5	0.1	0.8	0.0	1.0	1.1	0.7	0.8	1.5	1.1
Ever highly irritable/argumentative for 2 days	0.5	0.6	1.6	0.9	0.6	0.4	0.7	1.0	0.7	0.6	-0.5	0.9	1.3	0.7	0.8	1.2	0.7	0.4	0.8
Birth weight	0.5	1.1	2.2	-1.5	-1.1	-0.1	-1.1	-1.0	-1.1	-1.2	-1.0	-1.2	-1.4	-1.0	-0.9	-0.4	-1.0	-0.8	-0.9
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.6	4.1	-2.0	-0.6	-0.0	-0.5	-0.9	-0.7	-1.0	-0.5	-0.9	-0.3	-0.5	-0.3	-0.3	-0.7	-0.2	-0.3
Eye problems/disorders: None of the above	0.5	0.6	2.2	0.7	-0.5	-1.2	-0.7	0.1	-0.5	0.3	-0.1	0.0	-0.9	-0.9	-0.9	-1.5	-0.2	-0.6	-0.8
Angina (self-reported)	0.5	0.7	1.7	-0.8	-1.0	0.1	-0.2	-1.0	-0.9	-1.3	-1.1	-0.8	-1.1	-0.3	-0.1	-0.4	-0.5	-1.2	-0.2
Mean time to correctly identify matches	0.5	1.0	9.6	-0.8	-1.1	1.1	-0.4	-0.3	-1.0	-0.7	-0.5	-0.6	-0.0	-0.3	-0.0	-0.7	-0.2	-3.1	-0.0
Illnesses of siblings: Diabetes	0.5	0.6	2.5	-0.4	0.6	0.8	1.0	-0.0	0.5	-0.3	-0.2	0.2	0.3	1.0	1.1	1.6	0.7	0.1	1.1
Long-standing illness, disability or infirmity	0.5	0.7	3.1	-1.6	0.0	0.5	0.3	-1.2	0.1	-1.2	-0.1	-0.8	-0.5	0.2	0.2	1.8	0.1	-1.3	0.2
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.6	2.8	-1.7	-0.5	0.5	-0.4	-0.1	-0.7	-0.2	0.6	-0.7	-1.0	-0.2	-0.1	-1.6	-0.6	-0.2	-0.0
Osteoarthritis (self-reported)	0.5	0.6	2.9	0.4	0.6	1.0	0.6	1.0	0.6	0.8	1.7	0.7	0.3	0.5	0.5	-0.9	0.5	-1.0	0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.0	3.5	-1.0	-0.7	-1.1	-1.1	-1.1	-0.7	-0.9	-0.6	-1.1	0.3	-0.9	-1.0	-1.9	-0.5	-1.1	-1.0
Arm fat mass (left)	0.5	1.9	12.3	-1.9	0.3	2.4	0.6	0.0	0.5	-0.3	2.0	-0.2	1.0	0.6	0.8	0.9	0.9	-3.5	0.8
Wears glasses or contact lenses	0.5	0.5	3.8	-0.7	-0.4	-0.2	-0.0	-0.6	-0.3	-1.1	-2.0	-0.4	0.6	0.3	0.2	-0.1	-0.0	-1.3	0.2
Schizophrenia (2018)	0.4	0.8	2.9	-0.1	-1.1	0.3	-0.9	-0.2	-1.1	-0.5	-0.5	-0.8	-1.7	-0.9	-0.8	-1.4	-0.8	-0.2	-0.8
Reaction Time	0.4	0.7	6.5	-0.9	-0.7	0.8	-0.3	0.0	-0.5	-0.2	0.6	-0.3	-0.2	-0.4	-0.3	-1.1	-0.2	-2.5	-0.2
Neuroticism (2016)	0.4	0.6	2.1	-0.4	0.6	0.8	0.8	0.3	0.9	-0.1	0.0	0.3	1.0	1.1	1.1	1.4	0.9	-0.1	0.9
Primary Biliary Cirrhosis	0.4	0.6	3.5	0.1	0.2	0.2	0.7	0.1	0.3	-0.2	-0.8	0.2	1.0	0.7	0.7	1.9	0.5	1.1	0.7
Blood White Count	0.4	2.9	5.8	1.1	1.4	2.0	2.2	1.3	1.7	0.6	0.4	1.6	1.8	2.2	2.3	2.4	1.4	0.3	2.3
Systolic Blood Pressure	0.4	1.8	4.4	-1.6	-0.9	-1.4	-0.7	-1.8	-1.1	-1.7	-2.1	-1.3	-0.8	-0.9	-0.7	2.0	-1.2	0.9	-0.7
Tanning	0.4	4.4	7.6	-2.0	-2.3	-2.8	-2.0	-2.2	-2.3	-2.3	-1.7	-2.1	-2.0	-2.0	-2.0	-1.7	-2.0	-1.6	-2.0
Hearing difficulty/problems: Yes	0.4	0.6	3.8	-1.1	-0.5	-0.1	-0.3	-0.7	-0.3	-0.8	-0.7	-0.6	-1.3	-0.2	-0.2	-0.2	-0.2	-2.0	-0.3
Vitamin and mineral supplements	0.4	0.6	1.3	-0.2	-0.8	-0.4	-1.0	-0.9	-1.0	-0.5	-0.5	-0.8	-0.3	-0.9	-0.9	-0.5	-0.8	-1.2	-0.9
Trunk fat percentage	0.4	1.7	8.5	-0.7	0.3	2.3	1.1	0.5	0.5	-0.2	1.2	0.4	0.5	1.2	1.4	1.1	1.3	-2.9	1.4
Taking other prescription medications	0.4	0.7	2.0	-0.8	-1.1	0.1	-0.6	-1.2	-0.9	-1.4	-1.0	-1.1	-0.6	-0.4	-0.3	0.7	-0.3	-0.7	-0.3
Trunk fat mass	0.4	1.7	12.6	-1.5	-0.1	2.4	0.6	0.0	0.1	-0.7	1.4	-0.2	0.4	0.7	0.8	0.5	0.9	-3.6	0.9
Alcohol usually taken with meals	0.4	0.7	1.4	0.0	0.9	1.2	1.1	0.8	0.9	0.6	1.0	0.7	0.9	1.1	1.0	-0.5	0.8	-0.2	1.0
Weight	0.4	2.1	16.2	-2.4	-0.3	2.4	0.1	-0.4	-0.0	-0.9	1.9	-0.8	0.7	0.1	0.2	0.1	0.6	-4.0	0.2
Happiness	0.4	0.5	1.7	1.0	0.5	0.8	0.5	0.9	0.6	0.4	-0.2	0.5	-0.8	0.5	0.6	0.7	0.4	1.3	0.6
Prospective memory result	0.4	0.5	1.7	0.1	0.8	0.3	0.8	0.4	0.8	0.3	0.5	0.6	-0.0	0.8	0.8	0.8	0.5	1.3	0.7
Blood clot in the leg (DVT)	0.4	0.5	1.1	-0.4	0.6	0.8	1.0	0.6	0.6	0.4	-0.2	0.9	-0.2	1.0	1.0	0.7	0.4	0.5	1.1
Headache pain in last month	0.4	0.7	2.0	0.7	0.6	0.8	0.2	1.1	0.6	1.3	1.4	0.8	0.3	-0.1	-0.1	-1.4	0.7	-1.3	-0.2
Health satisfaction	0.4	0.5	4.8	-0.4	0.3	0.8	0.6	-0.7	0.5	-0.7	-0.4	-0.5	0.0	0.3	0.5	2.2	0.4	-0.0	0.5
Migraine (self-reported)	0.4	0.5	4.1	0.3	-0.0	0.6	0.4	0.4	0.2	-0.1	-0.3	0.3	0.8	0.5	0.6	-0.1	0.8	-2.0	0.7
Medication: Omeprazole	0.4	0.5	1.4	-0.2	-1.2	-0.7	-0.7	-0.8	-1.0	-0.8	-1.1	-0.7	-0.6	-0.6	-0.6	0.1	-0.7	0.3	-0.6
Heart disease (mother)	0.4	0.5	1.3	0.4	0.2	1.1	0.8	0.9	0.3	0.5	-0.1	0.8	0.6	1.0	1.1	0.1	0.9	0.3	1.1
Whole body fat mass	0.4	1.9	10.9	-1.4	0.2	2.7	0.8	0.3	0.4	-0.3	1.7	0.0	0.8	0.9	1.1	1.0	1.1	-3.3	1.1
Comparative height size at age 10	0.4	2.4	9.2	-2.6	-1.7	-0.1	-1.2	-1.8	-1.5	-2.5	-0.8	-2.0	-0.2	-0.8	-0.8	-0.2	-0.5	-3.0	-0.8
Smoking status: Previous	0.4	0.5	2.2	-0.3	-0.6	-0.5	-0.6	-0.7	-0.6	-0.5	-0.0	-0.9	-1.5	-0.7	-0.7	-0.5	-1.1	-0.7	-0.8
Ever had bowel cancer screening	0.4	0.5	2.0	-0.6	-0.7	-0.3	-0.4	-0.7	-0.5	-1.0	-0.9	-0.5	0.6	-0.3	-0.2	-0.7	-0.6	-1.4	-0.2
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	4.4	-0.7	0.1	-0.9	-0.3	-0.1	0.2	0.0	-0.0	-0.1	-1.3	-0.6	-0.6	-0.9	-0.7	2.1	-0.5
Medication: Aspirin	0.4	0.5	1.3	-1.1	-0.7	-0.3	-0.4	-0.9	-0.6	-1.1	-1.1	-0.6	-0.5	-0.2	-0.2	-1.0	-0.7	0.1	-0.2
Number of self-reported non-cancer illnesses	0.4	0.7	2.5	-1.2	-0.5	0.9	0.3	-1.1	-0.3	-1.6	-1.3	-0.6	0.0	0.5	0.6	1.0	0.2	-0.8	0.6
High cholesterol (Self-reported)	0.4	0.8	3.3	-1.1	-0.6	0.5	0.1	-1.0	-0.4	-1.7	-0.8	-0.7	-0.5	0.3	0.4	1.0	-0.1	-1.8	0.4
Ever had prostate specific antigen (PSA) test	0.4	0.5	2.2	0.1	-1.1	0.0	-0.4	-0.2	-1.0	-0.5	-1.5	-0.4	0.3	-0.1	0.0	-1.3	-0.6	-0.9	0.0
Fractured/broken bones in last 5 years	0.4	0.5	2.5	-1.3	-0.7	-0.1	-0.3	-0.9	-0.6	-0.8	-0.1	-0.6	-1.6	-0.4	-0.3	0.1	-0.8	0.2	-0.2
Cholesterol lowering medication	0.4	0.7	2.4	-0.3	0.1	1.6	0.8	0.4	0.3	-0.2	0.5	0.6	0.7	1.1	1.1	-0.1	1.1	-1.1	1.2
Depression (Nagel 2018)	0.3	0.4	2.5	-1.2	-0.8	0.8	-0.6	-0.2	-0.7	-0.6	-0.4	-0.5	-0.0	-0.3	-0.2	0.1	-0.1	-1.6	-0.2
Neuroticism (Nagel 2018)	0.3	0.6	2.6	-1.6	-0.7	0.5	-0.5	-0.8	-0.6	-1.2	-0.4	-0.7	-0.8	-0.2	-0.2	-0.1	-0.4	-1.3	-0.2
Crohns Disease (2012)	0.3	0.4	1.6	1.0	-0.1	-0.6	0.2	0.9	0.0	0.5	0.0	0.8	0.3	0.4	0.5	-1.2	0.1	1.3	0.5
HbA1C	0.3	0.3	0.9	0.4	-1.0	-0.4	-0.5	-0.4	-0.8	-0.7	-0.9	-0.6	0.1	-0.2	0.0	-0.8	-0.6	-0.1	-0.1
LDL Cholesterol	0.3	0.5	3.5	1.0	0.9	-0.2	0.3	0.3	0.8	0.6	-0.1	0.4	0.4	0.2	0.1	1.9	0.5	1.0	0.2
Type 2 Diabetes (T2D) (2012)	0.3	0.4	2.9	0.8	-0.1	-0.8	0.1	0.4	0.0	0.5	-0.3	0.6	-0.4	-0.0	-0.1	-1.0	-0.1	1.7	-0.2
Blood Platelet Count	0.3	3.3	6.6	-2.0	-2.1	-0.8	-1.5	-2.3	-2.0	-2.6	-2.4	-2.2	-1.4	-1.8	-1.3	-0.4	-1.7	-1.7	-1.3
Blood Red Count	0.3	2.7	6.9	-0.5	-1.7	-1.6	-1.4	-1.9	-1.6	-1.8	-2.0	-1.9	-2.6	-1.6	-1.3	0.6	-2.1	-1.1	-1.3
Waist Hip Ratio (WHR)	0.3	1.2	1.9	1.4	1.3	0.5	1.3	1.3	1.4	1.2	0.5	1.2	0.7	1.2	1.2	1.2	0.9	0.9	1.1
Smoking Status	0.3	0.7	1.2	-0.9	-0.6	-0.6	-0.9	-0.9	-0.7	-0.9	0.0	-1.0	-1.1	-0.9	-1.0	0.2	-0.6	-0.7	-1.0
Neuroticism	0.3	0.7	2.9	-1.5	-0.8	0.5	-0.7	-0.7	-0.7	-1.1	-0.2	-0.8	-0.7	-0.4	-0.4	0.6	-0.2	-1.7	-0.5
Number of treatments/medications taken	0.3	0.5	1.3	-0.4	-1.2	-0.2	-0.6	-0.4	-1.1	-0.9	-0.8	-0.5	-0.9	-0.3	-0.3	-0.6	-0.3	-1.0	-0.3
Average weekly spirits intake	0.3	0.3	1.4	-0.4	0.7	0.8	0.5	0.2	0.6	0.3	0.7	0.3	-0.5	0.4	0.4	1.2	0.1	0.6	0.5
Angina	0.3	0.4	1.0	-0.5	-0.8	0.3	-0.0	-0.7	-0.7	-0.9	-1.0	-0.5	-0.8	-0.0	0.1	-0.3	-0.2	-1.0	0.1
Impedance of leg (right)	0.3	1.4	5.3	2.3	0.0	-1.3	0.8	-0.0	0.1	-0.3	-1.9	0.5	-1.5	0.8	0.9	1.5	0.3	1.9	1.0
Fed-up feelings	0.3	0.5	1.8	-1.1	-0.7	0.4	-0.1	-0.4	-0.7	-0.8	-1.1	-0.5	-0.7	0.0	0.1	1.3	-0.1	-0.8	0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.4	1.1	-0.5	-0.9	0.1	-0.6	-0.0	-0.8	-0.4	-1.1	-0.4	-1.0	-0.4	-0.3	0.7	-0.0	-0.9	-0.3
Multivitamins +/- minerals	0.3	0.4	1.0	0.2	0.5	0.5	0.6	1.0	0.6	0.7	0.8	0.7	0.8	0.5	0.5	0.1	0.7	0.4	0.5
Stomach or abdominal pain in last month	0.3	0.4	1.0	-0.3	-0.6	-0.8	-0.8	-0.5	-0.5	-0.5	-1.0	-0.4	0.3	-0.8	-0.7	-0.2	-0.4	-0.5	-0.7
Diverticular disease/diverticulitis (self-reported)	0.3	0.3	1.5	0.6	-0.8	-0.8	-0.3	0.1	-0.6	-0.1	-1.2	-0.2	-0.4	-0.3	-0.2	-0.7	0.0	0.6	-0.2
Impedance of leg (left)	0.3	1.6	6.3	2.5	0.2	-1.0	1.0	0.5	0.3	0.1	-1.8	1.0	-1.5	1.1	1.2	1.5	0.5	1.9	1.2
Past tobacco smoking	0.3	0.5	2.9	0.7	0.6	-0.1	0.4	0.4	0.5	0.4	-0.3	0.8	1.7	0.5	0.5	0.4	0.9	0.9	0.5
Had other major operations	0.3	0.4	1.5	0.3	0.6	1.2	0.7	0.5	0.6	0.6	0.2	0.5	0.6	0.8	0.9	-0.1	0.2	0.0	0.9
Heart attack	0.3	0.4	3.3	0.2	-0.2	-0.6	-0.0	-0.8	-0.1	-0.8	-0.4	-0.5	-0.4	-0.2	-0.2	1.8	-0.1	-0.8	-0.2
Alcohol intake versus 10 years previously	0.3	0.5	1.9	-0.9	0.2	0.7	0.5	-0.2	0.3	-0.6	-0.4	-0.2	0.4	0.6	0.7	1.3	0.6	-1.4	0.7
Hair/balding pattern: Pattern 3	0.3	0.5	1.1	0.2	-0.7	-0.4	-0.4	-0.9	-0.6	-1.0	-1.0	-0.8	-0.3	-0.5	-0.5	-1.0	-0.4	-0.8	-0.4
Impedance of arm (left)	0.3	1.2	6.1	0.7	-0.7	-1.9	-0.1	-0.8	-0.6	-1.1	-2.5	-0.3	-1.8	-0.0	0.1	1.2	-0.5	1.2	0.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.5	1.3	0.3	0.6	0.5	0.8	0.5	0.8	0.4	0.4	0.4	0.1	0.9	1.0	1.2	0.8	0.1	0.9
Peak expiratory flow (PEF)	0.3	0.6	2.3	-1.5	-0.1	0.3	-0.8	-0.2	-0.2	-0.1	1.1	-0.6	0.4	-0.5	-0.7	-1.4	-0.1	-1.2	-0.7
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	2.4	-1.6	0.2	0.7	0.4	-0.4	0.1	-0.5	-0.1	-0.4	-1.0	0.3	0.4	0.8	0.0	-0.4	0.5
Qualifications: College or University degree	0.3	0.9	3.7	0.6	0.9	1.2	0.8	0.8	1.0	1.0	1.1	0.6	1.9	0.6	0.7	0.7	0.7	0.8	0.7
Medication: Ibuprofen	0.3	0.4	1.6	0.3	-0.2	0.6	-0.2	1.1	-0.2	0.8	0.3	0.6	-0.4	0.1	0.1	-1.3	0.6	-1.0	0.0
Pulse rate, automated reading	0.3	1.0	3.6	-0.7	-1.0	-0.0	-0.7	-1.0	-1.2	-1.0	-1.1	-1.3	-1.9	-0.7	-0.6	-0.9	-1.0	-1.3	-0.5
Commuting to job workplace: Car/motor vehicle	0.3	0.4	1.4	-0.5	-0.1	1.2	0.4	0.5	0.1	0.5	0.5	0.5	1.2	0.4	0.4	0.9	0.7	-0.3	0.5
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	1.2	0.9	-0.2	-1.1	-0.6	0.1	-0.2	0.2	-0.1	-0.0	-0.3	-0.9	-0.8	-1.1	-0.3	0.3	-0.8
Knee pain experienced in last month	0.3	0.5	2.2	-1.4	0.1	0.7	0.2	-0.3	0.0	0.0	1.5	-0.2	0.3	0.1	0.1	1.4	0.2	0.6	0.1
Eye problems/disorders: Cataract	0.3	0.3	0.7	-0.5	-0.4	-0.3	-0.7	-0.7	-0.4	-0.5	-0.5	-0.8	-0.2	-0.8	-0.7	-0.8	-0.6	0.1	-0.7
Financial situation satisfaction	0.3	0.4	1.1	0.4	0.6	0.8	0.5	0.6	0.6	0.7	0.9	0.4	0.6	0.5	0.6	1.1	0.5	0.3	0.6
Pain experienced in last month	0.3	0.6	1.6	-0.1	-0.5	-0.7	-0.5	-0.9	-0.6	-1.1	-1.3	-0.8	-1.0	-0.6	-0.7	-0.6	-0.9	-0.2	-0.6
Heart attack/myocardial infarction (self-reported)	0.3	0.4	3.3	0.2	-0.2	-0.6	-0.0	-0.8	-0.2	-0.8	-0.6	-0.6	-0.5	-0.1	-0.1	1.8	-0.2	-0.7	-0.1
Impedance of whole body	0.3	1.4	6.5	1.5	-0.6	-1.6	0.3	-0.3	-0.4	-0.7	-2.6	0.2	-1.9	0.4	0.5	1.3	-0.2	1.7	0.6
Bipolar Disorder or Schizophrenia	0.2	0.5	1.4	0.3	-0.9	0.7	-0.9	0.2	-1.1	-0.1	0.2	-0.6	-1.1	-0.7	-0.6	-1.2	-0.5	-0.5	-0.6
Alzheimer’s Disease (including proxy)	0.2	0.3	1.6	0.6	0.3	-0.3	-0.1	0.7	0.1	0.8	0.2	0.5	0.7	-0.0	-0.0	-0.0	0.3	1.3	-0.0
Crohns Disease (2017)	0.2	0.5	2.5	0.8	0.1	-0.2	0.5	1.0	0.2	0.6	0.1	0.8	-0.5	0.6	0.6	-0.6	0.3	1.6	0.7
Rheumatoid Arthritis	0.2	0.2	0.4	0.2	0.6	-0.0	0.7	0.3	0.7	0.3	0.0	0.4	0.5	0.6	0.5	0.1	0.5	-0.6	0.5
Cardiovascular Disease	0.2	0.7	2.3	-1.1	-0.2	1.5	0.8	-0.1	-0.1	-0.8	-0.3	0.2	0.3	0.9	1.2	1.5	0.4	-0.1	1.2
Hair Pigment	0.2	5.0	12.8	1.7	2.4	2.1	2.2	2.0	2.5	1.6	2.7	2.0	1.8	2.2	2.1	3.6	2.5	1.4	2.1
Ever had hysterectomy (womb removed)	0.2	0.2	1.5	-0.2	0.1	0.6	-0.0	-0.4	0.0	-0.5	-0.5	-0.1	-0.4	0.1	0.0	1.2	-0.2	0.7	0.0
Systolic blood pressure, automated reading	0.2	0.6	3.4	-0.1	0.6	0.8	1.0	0.0	0.6	-0.0	-0.2	0.6	0.7	0.9	1.0	1.9	0.3	0.1	1.1
Townsend deprivation index at recruitment	0.2	0.3	1.1	-0.6	-0.0	-0.3	-0.2	-0.8	-0.1	-1.0	-0.0	-0.6	-0.7	-0.1	-0.1	1.0	0.1	-0.1	-0.1
Qualifications: CSEs or equivalent	0.2	0.3	1.0	1.0	0.4	-0.2	-0.1	0.4	0.4	0.6	0.8	0.3	-0.7	-0.2	-0.3	0.4	0.2	0.6	-0.3
Mouth/teeth dental problems	0.2	0.2	1.2	1.1	0.1	0.4	-0.1	0.5	0.1	0.5	-0.1	0.3	0.6	0.2	0.1	0.2	0.4	1.0	0.1
Hayfever/allergic rhinitis (self-reported)	0.2	0.3	2.2	-0.2	-0.1	0.1	-0.1	-0.2	-0.1	-0.1	0.1	-0.2	0.2	-0.2	-0.3	-0.8	0.8	-1.5	-0.3
Medication: Simvastatin	0.2	0.3	0.9	0.1	-0.6	0.9	0.4	0.1	-0.4	-0.6	-0.5	0.3	-0.1	0.7	0.8	-0.6	0.2	-0.4	0.8
Impedance of arm (right)	0.2	1.0	5.2	0.6	-0.6	-2.0	0.0	-0.8	-0.5	-0.9	-2.3	-0.3	-1.5	0.0	0.2	0.9	-0.5	1.3	0.2
Worrier / anxious feelings	0.2	0.4	1.5	-1.2	-0.6	-0.3	-0.3	-0.9	-0.4	-1.2	-0.9	-0.7	-1.0	-0.2	-0.3	0.3	-0.3	0.0	-0.3
Falls in the last year	0.2	0.3	1.6	-0.3	0.8	-0.1	0.5	-0.1	1.0	0.0	1.3	0.1	-0.6	0.3	0.2	0.2	0.1	-0.3	0.3
Mouth/teeth dental problems: Dentures	0.2	0.3	3.2	0.0	0.0	-0.2	0.2	-0.1	-0.0	-0.1	-0.1	0.1	0.9	0.1	0.2	-0.0	0.1	-1.8	0.2
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.3	0.7	-0.5	0.0	0.4	-0.0	0.8	0.0	0.8	0.8	0.4	-0.6	0.1	0.1	-0.8	0.6	-0.8	0.1
Medication: Cholesterol lowering	0.2	0.3	1.1	0.7	-0.2	0.3	0.3	-0.3	-0.1	-0.8	-0.7	-0.1	-0.5	0.5	0.5	1.0	0.1	-0.3	0.5
Medication for cholesterol, blood pressure or diabetes	0.2	0.4	1.3	-0.0	0.8	-0.5	0.0	0.6	0.7	1.2	0.7	0.4	0.9	-0.2	-0.3	-1.0	0.2	0.6	-0.3
Medication: Ventolin 100micrograms inhaler	0.2	0.3	2.2	0.2	-0.3	0.6	-0.2	-0.3	-0.2	-0.5	-0.1	-0.3	-0.5	0.0	0.1	-1.5	-0.1	0.7	-0.0
Medication for pain relief, constipation, heartburn	0.2	0.4	1.4	0.3	0.9	0.4	0.7	0.1	0.8	0.3	0.3	0.3	1.0	0.6	0.5	0.8	0.2	1.2	0.6
Medication: Blood pressure	0.2	0.4	2.4	-0.3	-0.4	0.9	0.5	0.1	-0.3	-0.4	-0.3	0.2	0.2	0.6	0.8	1.6	0.4	0.1	0.8
Leg pain on walking	0.2	0.2	0.6	-0.1	0.5	0.2	0.6	0.1	0.6	-0.1	0.8	0.5	0.7	0.4	0.4	0.6	-0.0	0.4	0.5
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.3	1.3	-0.8	-0.2	-0.4	-0.5	-0.2	-0.1	-0.4	-0.3	-0.5	-1.1	-0.5	-0.5	-0.6	-0.4	-0.2	-0.5
Mood swings	0.2	0.4	1.3	-1.0	-0.5	-0.4	-0.3	-0.8	-0.3	-1.1	-0.9	-0.4	-0.6	-0.4	-0.5	1.0	-0.5	-0.7	-0.5
Mineral and other dietary supplements	0.2	0.3	1.6	0.7	0.1	0.3	0.2	0.6	-0.2	0.7	0.3	0.4	-0.0	0.3	0.4	-0.0	0.4	1.3	0.4
Average weekly champagne plus white wine intake	0.2	0.3	1.0	-0.6	-0.6	0.4	-0.4	-0.0	-0.6	-0.4	-0.9	-0.4	-1.0	-0.2	-0.1	-1.0	-0.8	0.0	-0.2
Commuting to job workplace: Public transport	0.2	0.2	0.8	0.9	0.1	0.6	0.4	0.5	0.0	0.2	0.5	0.3	-0.4	0.5	0.6	-0.4	0.0	-0.6	0.5
Medication: Blood pressure	0.2	0.5	2.7	-0.7	-0.6	0.3	-0.3	-0.7	-0.6	-0.6	0.0	-0.4	0.4	-0.4	-0.4	-1.1	-0.6	-1.6	-0.4
Alcohol drinker status: Never	0.2	0.2	0.9	0.9	0.7	0.2	0.5	0.6	0.7	0.6	0.4	0.6	0.1	0.4	0.4	0.1	0.3	0.1	0.4
Vascular/heart problems diagnosed by doctor	0.2	0.4	1.9	1.4	0.7	-0.6	-0.0	0.9	0.6	1.0	0.4	0.4	-0.1	0.1	-0.1	0.3	0.2	1.3	-0.2
Deep venous thrombosis (DVT) (self-reported)	0.2	0.3	0.6	-0.3	0.3	0.7	0.7	0.5	0.4	0.2	-0.5	0.7	-0.4	0.8	0.8	0.4	0.1	0.4	0.8
Bipolar Disorder (2018)	0.1	0.2	0.8	0.6	-0.2	0.8	-0.2	0.5	-0.3	0.5	0.9	0.1	0.6	-0.1	0.0	-0.2	0.3	-0.5	0.1
Alzheimer’s Disease (in mother)	0.1	0.2	0.5	0.4	-0.2	-0.2	-0.5	0.2	-0.3	0.4	0.4	0.2	0.6	-0.4	-0.5	-0.7	0.2	-0.3	-0.5
Ovarian Cancer	0.1	0.1	0.4	-0.3	-0.2	-0.2	-0.3	-0.4	-0.2	-0.2	0.6	-0.1	-0.5	-0.2	-0.0	-0.2	-0.1	-0.4	0.0
Respiratory disease	0.1	0.2	0.7	0.4	-0.1	-0.4	-0.3	-0.6	-0.2	-0.4	-0.8	-0.5	-0.6	-0.2	-0.2	0.7	-0.2	0.8	-0.2
Relative age of first facial hair	0.1	0.2	2.1	0.1	-0.1	-0.1	0.2	-0.2	-0.1	0.1	0.2	0.0	-0.7	0.1	0.0	1.4	0.1	0.4	-0.0
Medication: Co-codamol	0.1	0.1	0.7	-0.6	-0.4	0.6	0.0	0.1	-0.2	0.0	0.0	-0.0	0.2	0.3	0.4	-0.1	0.4	-0.8	0.3
Average weekly fortified wine intake	0.1	0.1	0.7	0.8	-0.0	0.2	-0.3	0.2	-0.0	-0.2	0.4	0.0	0.6	-0.3	-0.4	-0.7	-0.3	-0.1	-0.4
High blood pressure	0.1	0.4	1.4	-1.2	-0.4	1.2	0.4	-0.3	-0.3	-0.7	0.0	0.1	0.3	0.4	0.6	-0.3	0.1	-1.2	0.6
Supplements: Glucosamine	0.1	0.1	0.5	-0.5	0.3	0.1	0.2	-0.3	0.3	-0.2	0.5	-0.2	0.7	0.2	0.2	0.3	0.0	-0.6	0.1
Number of incorrect matches in round	0.1	0.2	1.1	0.2	0.1	0.8	0.3	0.5	0.2	0.0	-0.2	0.4	-0.0	0.3	0.4	1.0	0.2	0.3	0.4
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.2	1.4	0.3	-0.1	0.6	-0.1	0.5	0.1	0.5	0.4	0.0	-0.8	-0.1	-0.1	1.2	0.5	-0.4	-0.1
Allergy	0.1	0.1	1.3	0.4	-0.0	-0.2	-0.2	-0.4	-0.1	-0.2	0.3	-0.0	1.1	-0.1	-0.1	-0.3	-0.4	-0.3	-0.1
Qualifications: A levels/AS levels or equivalent	0.1	0.2	0.9	-0.1	-0.2	0.1	-0.4	-0.4	-0.1	-0.3	-0.0	-0.7	0.4	-0.5	-0.7	0.6	-0.4	-0.9	-0.7
Asthma	0.1	0.2	0.9	-0.2	-0.2	-0.3	-0.3	-0.5	-0.3	-0.3	-0.7	-0.6	-0.9	-0.3	-0.3	-0.5	-0.1	0.6	-0.3
Illnesses of mother	0.1	0.1	0.5	-0.0	0.1	-0.4	-0.3	-0.3	-0.0	0.1	-0.0	-0.3	-0.7	-0.5	-0.5	-0.2	-0.6	0.0	-0.5
Pulse wave Arterial Stiffness index	0.1	0.2	0.9	-0.6	-0.1	-0.4	0.4	-0.3	-0.2	-0.4	-1.0	-0.1	-0.3	0.4	0.5	-0.0	-0.1	-0.4	0.5
Tense / ‘highly strung’	0.1	0.2	0.9	0.7	0.1	0.5	0.1	0.5	0.3	0.5	0.9	0.4	0.4	0.2	0.3	-0.1	0.3	-0.9	0.3
Birth weight of first child	0.1	0.2	1.3	-0.3	0.5	0.1	0.2	-0.4	0.5	-0.1	0.4	-0.3	0.1	0.1	-0.1	1.2	0.2	-1.0	-0.1
Qualifications: O levels/GCSEs or equivalent	0.1	0.1	0.4	0.3	-0.3	0.2	-0.4	0.3	-0.6	0.5	0.6	-0.2	0.5	-0.3	-0.2	-0.4	-0.2	0.5	-0.3
Medication: Paracetamol	0.1	0.2	0.8	0.5	0.1	0.2	0.4	0.9	0.2	0.6	0.9	0.5	0.1	0.3	0.4	0.2	0.7	-0.6	0.3
Gout (self-reported)	0.1	0.1	0.6	-0.1	0.4	0.7	0.1	0.2	0.3	0.5	0.8	0.1	-0.1	-0.0	-0.1	0.2	0.5	-0.2	-0.0
Medication: Amlodipine	0.1	0.1	0.3	-0.3	-0.4	-0.4	-0.2	0.1	-0.5	0.1	-0.2	-0.2	-0.3	-0.1	-0.0	-0.1	-0.4	0.3	-0.1
Worry too long after embarrassment	0.1	0.2	2.0	-0.5	0.1	1.4	0.3	0.2	0.2	-0.3	0.1	0.0	0.1	0.5	0.5	0.2	0.3	0.1	0.5
Pulse wave peak to peak time	0.1	0.1	0.7	0.3	-0.0	0.4	-0.4	0.1	0.0	0.2	0.8	-0.0	0.2	-0.4	-0.5	0.0	0.0	0.4	-0.4
Shortness of breath walking on level ground	0.1	0.1	0.4	-0.2	-0.1	0.0	0.0	-0.4	-0.0	-0.3	0.2	-0.3	-0.2	-0.1	-0.0	-0.3	0.1	-0.6	-0.1
Mouth/teeth dental problems: Loose teeth	0.1	0.2	0.7	0.5	-0.6	-0.2	-0.2	0.3	-0.8	0.2	-0.8	-0.0	0.1	-0.0	0.0	-0.2	0.0	-0.8	0.1
Alcohol intake frequency.	0.1	0.2	0.7	-0.8	-0.3	-0.3	-0.2	-0.1	-0.2	-0.3	-0.9	-0.3	-0.1	-0.2	-0.1	-0.6	-0.3	-0.7	-0.2
Number of full sisters	0.1	0.1	0.5	-0.0	-0.1	0.4	-0.2	-0.2	-0.1	-0.2	-0.2	-0.3	-0.7	-0.3	-0.4	-0.5	-0.4	0.6	-0.4
Family relationship satisfaction	0.1	0.2	0.7	0.0	-0.2	0.6	-0.4	0.1	-0.2	-0.3	0.0	-0.1	-0.8	-0.3	-0.3	-0.7	0.2	-0.4	-0.4
Hypertension (Self-reported)	0.1	0.3	1.1	-1.1	-0.5	1.0	0.3	-0.4	-0.4	-0.8	-0.3	0.0	0.5	0.3	0.5	-0.2	-0.1	-0.9	0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.1	0.7	-0.1	-0.1	-0.0	0.2	-0.2	0.1	-0.1	0.2	0.2	0.4	0.3	0.3	0.8	0.2	0.7	0.3
Illnesses of father: Heart disease	0.1	0.1	1.5	0.3	0.1	0.4	0.0	0.3	0.2	0.4	0.4	0.1	0.2	0.0	0.0	-1.2	0.0	0.2	0.0
Average weekly red wine intake	0.1	0.1	0.7	-0.4	-0.3	-0.1	0.0	-0.0	-0.2	-0.2	0.0	-0.2	-0.5	0.1	0.1	-0.8	-0.4	0.5	0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.1	0.2	2.0	-0.0	0.0	0.2	-0.2	0.1	0.1	-0.1	0.1	-0.0	-0.5	-0.3	-0.4	0.2	0.3	-1.4	-0.3
Back pain experienced in last month	0.1	0.2	1.4	-0.7	0.0	0.2	0.3	0.0	0.0	-0.1	0.0	-0.1	0.0	0.4	0.4	1.2	0.4	-0.5	0.4
Asthma (self-reported)	0.1	0.2	0.8	-0.1	-0.1	-0.3	-0.2	-0.5	-0.2	-0.3	-0.6	-0.5	-0.9	-0.2	-0.1	-0.4	-0.1	0.7	-0.1
Ever taken oral contraceptive pill	0.1	0.2	0.9	-0.3	0.3	-0.1	0.2	-0.7	0.2	-0.3	0.0	-0.5	-1.0	-0.1	-0.0	0.5	-0.0	0.3	0.1
Pain type(s) experienced in last month: Hip pain	0.1	0.1	0.4	0.2	0.2	-0.2	-0.3	0.1	0.3	0.2	-0.1	0.1	0.6	-0.4	-0.4	0.5	0.1	0.1	-0.5
Average weekly beer plus cider intake	0.1	0.2	1.2	0.5	-0.3	0.7	-0.2	-0.0	-0.3	0.0	0.2	0.3	1.1	0.1	0.1	0.1	0.3	-0.4	0.1
Schizophrenia vs Biploar Disorder	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	-0.4	-0.4	-0.2	-0.0	-0.4	-0.4
Major Depression (MDD)	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	-0.3	0.0	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Current tobacco smoking	0.0	0.1	0.2	-0.2	0.1	0.1	-0.3	0.1	-0.1	0.1	0.3	0.1	0.3	-0.2	-0.2	0.4	0.4	-0.3	-0.2
Smoking status: Current	0.0	0.0	0.2	-0.5	0.1	0.2	-0.3	0.1	-0.1	0.1	0.3	-0.0	-0.2	-0.2	-0.2	0.2	0.3	-0.2	-0.3
Supplements: Fish oil (including cod liver oil)	0.0	0.1	0.2	-0.2	0.1	0.1	-0.0	-0.2	0.3	-0.4	-0.2	-0.1	0.1	-0.0	-0.0	0.5	0.0	-0.5	-0.0
Medication: Paracetamol	0.0	0.1	0.3	0.4	-0.4	-0.2	-0.2	0.5	-0.4	0.1	-0.0	0.2	0.0	-0.1	-0.2	0.0	-0.1	-0.5	-0.2
Irritability	0.0	0.1	0.4	-0.0	-0.2	0.4	-0.2	0.4	-0.3	0.2	0.1	0.1	-0.2	-0.2	-0.2	-0.7	0.1	-0.2	-0.2

Hub : Genes

DIDO1

Models

Trait associations