TWAS hub - DLGAP1-AS2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Breast Mammary Tissue (Male)	0.102	0.122	0.2600	-0.008	NA	-0.008	NA	-0.006	0.56000	NA	5.3e-01	NA	4.6e-01
2	GTEx	Breast Mammary Tissue (Female)	0.183	0.121	0.1200	0.096	NA	0.147	NA	0.187	0.00084	NA	3.7e-05	NA	3.0e-06
3	GTEx	Ovary	0.361	0.109	0.0064	-0.011	NA	-0.012	NA	0.021	0.77000	NA	8.4e-01	NA	1.0e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Age when periods started (menarche)	6.2	15.0	42.2	6.5	0.9	1.4
Diabetes (father)	4.1	5.0	11.8	3.4	-0.1	-1.8
Chronic bronchitis/emphysema (father)	4.1	4.8	9.1	-3.0	-0.4	2.3
Shortness of breath walking on level ground	3.9	4.7	10.4	-1.5	1.2	-3.2
Medication: Co-codamol	3.8	4.4	9.7	-3.1	1.7	0.7
Alcohol drinker status: Never	3.5	4.2	7.1	0.2	-2.4	-2.7
Relative age voice broke	3.4	5.2	12.2	3.5	0.6	1.7
Hayfever, allergic rhinitis or eczema	3.3	7.2	19.4	4.4	-1.0	-1.2
Pulse wave reflection index	3.3	4.1	11.0	-3.3	-0.1	-1.1
Loud music exposure frequency	3.3	3.6	9.1	1.4	-3.0	0.1
Allergy or Eczema	3.2	8.3	21.7	4.7	-1.6	-0.9
Multivitamins +/- minerals	3.2	4.0	8.7	3.0	-0.2	-1.8
Financial difficulties in last 2 years	3.2	4.2	6.6	-1.3	-2.1	-2.6
Impedance of arm (left)	2.6	11.9	33.1	5.8	0.9	1.3
Blood clot in the leg (DVT)	2.6	3.4	6.4	-2.5	-1.9	0.6
Deep venous thrombosis (DVT) (self-reported)	2.5	3.2	6.0	-2.4	-1.8	0.5
Impedance of arm (right)	2.4	11.4	30.9	5.6	1.2	1.3
Hair/balding pattern: Pattern 2	2.3	2.9	4.0	2.0	1.8	1.2
Ovarian Cancer	2.2	3.0	5.2	-1.4	-2.3	1.3
Exposure to tobacco smoke outside home	2.2	2.9	4.7	-0.8	-2.2	-1.9
Overall health rating	2.2	4.7	6.4	-2.3	-1.6	-2.5
Qualifications: CSEs or equivalent	2.1	2.8	6.9	0.5	-2.6	-1.1
Allergy	2.1	4.7	9.1	-3.0	1.6	1.5
Osteoarthritis (self-reported)	2.1	2.7	4.5	-2.1	1.9	-0.3
Financial situation satisfaction	2.0	2.5	3.5	-1.3	-1.5	-1.9
Alzheimer’s Disease (in father)	1.9	2.0	5.2	-0.5	2.3	-0.8
Father’s age at death	1.9	2.6	5.6	2.4	1.5	0.0
Impedance of whole body	1.9	9.6	26.9	5.2	0.6	1.2
Eye problems/disorders: Diabetes related eye disease	1.8	2.0	3.8	-2.0	-0.5	-1.4
Severe depression (siblings)	1.8	2.0	4.9	2.2	0.0	-1.0
Hayfever/allergic rhinitis (self-reported)	1.8	2.4	4.0	2.0	-0.6	-1.6
Alcohol intake versus 10 years previously	1.8	2.7	7.1	0.3	-1.0	-2.7
Length of working week for main job	1.8	1.9	4.2	-1.0	0.8	-2.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.8	2.1	5.3	-0.1	-2.3	1.0
Medication: Bendroflumethiazide	1.8	2.8	7.5	-2.7	-0.9	0.2
Eye problems/disorders: None of the above	1.7	2.0	4.4	2.1	0.0	1.3
Average weekly beer plus cider intake	1.7	2.5	5.9	-0.3	-2.4	-1.3
Cholesterol lowering medication	1.7	2.5	3.4	-1.7	-1.8	-1.1
Frequency of unenthusiasm / disinterest in last 2 weeks	1.6	2.1	6.0	0.3	-2.5	0.4
Average weekly red wine intake	1.6	2.3	5.9	-0.5	2.4	0.9
Medication for cholesterol	1.6	2.4	3.6	1.9	1.4	1.2
Pain experienced in last month	1.6	2.6	4.6	-2.1	0.8	-1.6
Angina (self-reported)	1.5	1.9	3.6	-0.2	-1.5	-1.9
Leg pain on walking	1.5	1.9	3.4	-0.9	-1.8	-1.2
Hypertension (Self-reported)	1.5	4.2	7.7	-2.8	-2.2	-0.0
Illnesses of siblings: Diabetes	1.5	1.9	3.1	1.8	-0.9	-1.3
Friendships satisfaction	1.5	1.8	3.6	1.9	-1.4	0.1
Sensitivity / hurt feelings	1.4	2.5	5.3	-1.3	2.3	0.6
Relative age of first facial hair	1.4	2.9	6.1	2.5	1.2	1.1
Vitamin and mineral supplements	1.4	1.8	4.8	-2.2	-0.5	0.7
Supplements: Zinc	1.4	1.5	2.7	0.1	-1.4	-1.6
Had other major operations	1.4	1.8	4.6	-0.1	-0.8	2.2
Happiness	1.4	1.7	4.2	0.7	-2.0	-0.6
Medication: Amlodipine	1.4	1.9	5.3	-2.3	-0.5	0.5
Reason for reducing amount of alcohol drunk: Health precaution	1.4	1.6	2.6	1.5	0.2	1.6
Medication: Aspirin	1.4	1.9	2.9	-1.7	-1.4	-0.9
Medication: Blood pressure	1.4	2.7	6.6	-2.6	-0.9	-0.7
Supplements: Fish oil (including cod liver oil)	1.4	1.9	4.1	1.2	2.0	-0.1
Commuting to job workplace: Cycle	1.4	1.7	3.3	1.8	-1.2	0.7
Cardiovascular Disease	1.3	4.4	9.0	-2.0	-3.0	0.1
Ever had hysterectomy (womb removed)	1.3	1.5	3.2	1.8	-0.7	0.8
Medication for hormone replacement therapy	1.3	1.4	3.1	0.4	0.9	-1.8
Mouth/teeth dental problems	1.3	2.0	5.1	2.3	0.4	-0.8
Mouth/teeth dental problems: Bleeding gums	1.3	1.7	4.1	-2.0	0.6	0.7
Chronic bronchitis/emphysema (mother)	1.3	1.6	2.7	1.2	1.6	0.8
Health satisfaction	1.3	1.7	4.2	-1.0	0.2	-2.0
Medication: Omeprazole	1.3	1.5	2.2	-1.2	-1.5	-1.0
Had major operations	1.3	1.6	3.6	0.1	-1.9	-1.0
Alzheimer’s Disease (in mother)	1.2	1.4	3.2	-0.5	-1.8	-0.9
HbA1C	1.2	1.3	3.0	-0.4	1.7	0.8
Hand grip strength (right)	1.2	3.2	7.5	2.7	-0.3	-1.4
Tinnitus: Yes, but not now, but have in the past	1.2	1.3	2.7	0.9	-0.6	-1.6
High blood pressure (mother)	1.2	1.7	2.8	-1.7	-1.5	-0.3
Commuting to job workplace: Car/motor vehicle	1.2	1.4	2.9	-1.7	1.0	-0.5
Forced expiratory volume in 1-second (FEV1), predicted	1.2	2.6	4.6	1.8	-2.2	-0.1
Ever had bowel cancer screening	1.2	1.4	2.6	-1.6	-1.0	-0.7
Osteoporosis (self-reported)	1.2	1.4	3.6	-0.7	1.9	-0.4
Medication: Lisinopril	1.2	1.5	2.8	-1.7	-0.7	-1.1
Vascular/heart problems diagnosed by doctor	1.2	3.2	5.9	2.4	1.8	0.7
Supplements: Calcium	1.2	1.3	3.8	1.9	0.0	-0.2
Alzheimer’s Disease (including proxy)	1.1	1.6	3.1	-1.8	0.0	-1.3
Prostate Cancer	1.1	1.5	3.3	1.8	0.5	-1.0
Angina	1.1	1.4	2.9	-0.1	-1.2	-1.7
Average weekly fortified wine intake	1.1	1.3	2.9	-0.5	1.7	0.9
Hearing difficulty/problems with background noise	1.1	1.8	4.2	1.0	2.0	0.6
Illnesses of siblings	1.1	1.6	2.6	-1.2	1.6	0.8
Pulse rate	1.1	1.8	2.1	1.4	-1.2	1.4
Wheeze or whistling in the chest in last year	1.1	1.9	3.2	1.8	-1.5	-0.6
Chest pain or discomfort	1.1	1.6	3.9	0.6	-2.0	-0.7
Commuting to job workplace: Public transport	1.1	1.3	3.4	1.8	-0.5	-0.4
Ever had prostate specific antigen (PSA) test	1.1	1.3	1.9	-1.1	1.4	0.9
Systolic blood pressure, automated reading	1.0	2.9	5.2	-1.3	1.4	-2.3
High blood pressure	1.0	2.9	5.6	-2.4	-1.7	-0.6
Medication: Atenolol	1.0	1.2	1.6	-1.3	-0.7	-1.3
Number of incorrect matches in round	1.0	1.7	4.6	-2.1	-0.5	0.5
Medication: Paracetamol	1.0	1.6	3.4	0.7	-1.0	1.8
Medication: Ventolin 100micrograms inhaler	1.0	1.3	1.9	0.6	-1.3	-1.4
Pulse wave peak to peak time	1.0	1.1	2.5	1.6	0.3	0.9
Medication: Allopurinol	1.0	1.3	2.0	-1.4	-0.8	1.1
Alcohol intake frequency.	1.0	2.2	5.2	-0.3	-1.2	-2.3
Mineral and other dietary supplements	1.0	1.4	2.3	-1.5	-1.3	0.3
Medication: Aspirin	1.0	1.4	2.3	-1.5	-1.3	-0.2
Tinnitus: Yes, now most or all of the time	1.0	1.2	3.3	0.0	-0.4	1.8
Respiratory disease	0.9	1.9	2.6	1.1	1.6	-1.4
Hand grip strength (left)	0.9	2.3	3.8	1.7	-0.3	-1.9
Frequency of depressed mood in last 2 weeks	0.9	1.2	2.8	-0.4	-1.7	-0.9
Hearing difficulty/problems: Yes	0.9	1.4	2.1	1.4	0.4	1.4
Impedance of leg (right)	0.9	4.6	12.1	3.5	1.0	0.8
Alcohol usually taken with meals	0.9	1.5	3.3	-0.0	1.8	1.1
Ever unenthusiastic/disinterested for a whole week	0.9	1.1	2.9	-0.0	0.6	-1.7
Diabetes (self-reported)	0.9	1.4	2.4	-1.3	-0.0	-1.6
Medication: Lansoprazole	0.9	1.0	3.0	0.3	-0.0	1.7
Lung cancer (father)	0.9	1.1	2.3	1.0	0.1	1.5
Number of children fathered	0.9	1.1	2.8	-1.7	-0.5	0.4
Knee pain experienced in last month	0.9	1.4	1.5	-1.2	-1.2	-1.1
Illnesses of father: Heart disease	0.9	1.2	1.9	-1.4	-0.3	-1.3
Average weekly champagne plus white wine intake	0.9	1.2	2.4	1.0	1.6	-0.3
Hearing aid user	0.9	1.0	1.8	-1.3	0.8	0.8
Triglycerides	0.8	1.4	4.0	-0.2	-2.0	-0.2
Serious illness, injury or assault to yourself	0.8	1.0	1.6	-0.6	-1.0	-1.3
Supplements: Glucosamine	0.8	1.0	2.5	-0.8	-0.1	1.6
Impedance of leg (left)	0.8	4.0	11.3	3.4	0.2	0.9
Fluid intelligence score	0.8	1.6	3.0	-1.4	0.3	-1.7
Worrier / anxious feelings	0.8	1.5	2.1	-1.5	-0.7	1.3
Pulse wave Arterial Stiffness index	0.8	1.0	1.8	-1.4	-0.4	-0.9
Standing height	0.8	8.0	14.1	3.8	-2.2	2.3
Qualifications: O levels/GCSEs or equivalent	0.8	1.2	3.1	-0.3	-1.8	0.7
High blood pressure (siblings)	0.8	1.1	1.7	1.3	-0.7	-1.0
Forced vital capacity (FVC), Best measure	0.8	3.0	3.4	1.6	-1.8	1.8
Comparative body size at age 10	0.8	2.3	4.4	-2.1	0.3	-1.5
Number of full brothers	0.8	1.0	2.5	-1.6	0.1	0.6
Emphysema/chronic bronchitis	0.8	0.9	2.3	0.1	0.7	-1.5
Medication for pain relief, constipation, heartburn	0.8	1.3	2.2	0.4	1.2	-1.5
Neck or shoulder pain in last month	0.8	1.2	2.1	1.5	-1.1	-0.4
Medication: Blood pressure	0.8	1.5	2.3	-1.5	-1.4	0.4
Heart disease (mother)	0.8	0.9	2.4	0.5	0.4	1.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.8	0.9	2.5	0.3	0.3	-1.6
Smoking status: Previous	0.8	1.1	2.3	-0.8	-1.5	-0.7
Alcohol drinker status: Previous	0.8	0.9	2.0	-1.4	0.1	-0.8
Ulcerative Colitis (UC)	0.7	1.4	3.6	0.1	0.7	-1.9
Major Depression (MDD)	0.7	0.8	2.4	-0.2	1.6	0.2
Reaction Time	0.7	1.4	3.7	-0.5	1.9	-0.4
Lupus	0.7	1.0	2.7	0.1	-0.7	1.6
Neuroticism (2016)	0.7	1.0	1.9	-0.2	1.1	1.4
Type 2 Diabetes (T2D) (2012)	0.7	0.8	1.7	-0.6	-1.3	-0.7
Number of treatments/medications taken	0.7	1.2	2.0	0.4	-1.4	1.2
Diverticular disease/diverticulitis (self-reported)	0.7	0.9	1.5	-0.7	-0.8	-1.2
Nervous feelings	0.7	1.3	2.7	-0.5	-0.9	1.6
Pain all over the body in last month	0.7	0.7	2.0	-1.4	0.1	0.5
Forced expiratory volume in 1-second (FEV1)	0.7	2.4	4.6	1.1	-1.1	2.2
Breastfed as a baby	0.7	0.9	2.1	1.5	-0.3	-0.6
Worry too long after embarrassment	0.7	1.1	3.1	0.3	1.8	-0.3
Mood swings	0.7	1.2	1.9	-1.3	-1.4	0.2
Diabetes diagnosed by doctor	0.7	1.2	2.1	-1.1	-0.6	-1.5
Eye problems/disorders: Cataract	0.7	0.8	1.3	-0.5	-1.0	-1.1
Asthma (self-reported)	0.7	1.5	2.2	1.5	-0.3	-1.5
Wears glasses or contact lenses	0.7	0.9	2.1	-0.7	1.4	-0.1
Medication: Paracetamol	0.7	1.1	2.3	1.0	-0.1	1.5
Ulcerative Colitis	0.6	0.9	2.4	0.6	0.0	-1.6
Height	0.6	11.3	27.8	5.3	-0.7	2.4
Current tobacco smoking	0.6	1.0	1.5	-1.2	1.2	-0.2
Body mass index (BMI)	0.6	2.6	7.5	-2.7	-0.3	-0.4
Past tobacco smoking	0.6	1.2	1.7	1.3	1.2	0.5
Had menopause	0.6	0.7	2.1	-1.4	0.0	0.2
Forced vital capacity (FVC)	0.6	2.2	3.5	0.8	-1.6	1.9
Heart attack	0.6	0.8	1.7	-0.7	-1.3	-0.4
Asthma	0.6	1.2	2.3	1.5	-0.4	-1.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	2.0	2.9	1.5	-1.0	1.7
Birth weight of first child	0.6	1.1	1.8	1.3	-0.7	1.1
Arm fat-free mass (right)	0.6	3.2	5.9	-2.4	-1.9	0.1
Mean time to correctly identify matches	0.6	1.1	2.0	-1.1	1.4	0.0
Arm predicted mass (right)	0.6	3.0	5.6	-2.4	-1.9	0.1
Suffer from ‘nerves’	0.6	1.0	1.6	0.2	-1.3	1.1
Age at last live birth	0.6	0.9	1.9	0.5	-1.4	-0.8
Supplements: Vitamin C	0.6	0.7	1.3	0.7	-0.6	1.1
Handedness (chirality/laterality): Left-handed	0.6	0.7	1.4	0.7	-1.2	0.4
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.6	1.6	0.6	-1.3	0.2
Smoking status: Current	0.6	0.9	1.4	-1.2	1.2	0.1
Fractured/broken bones in last 5 years	0.6	0.8	2.0	1.4	0.6	0.1
Unable to work because of sickness or disability	0.6	0.7	1.9	0.2	-0.6	-1.4
Heart attack/myocardial infarction (self-reported)	0.6	0.7	1.3	-0.8	-1.1	-0.6
Depression (Nagel 2018)	0.5	0.7	1.0	-0.6	-0.9	-1.0
Irritable Bowel Disease (IBD)	0.5	1.3	3.2	0.2	0.8	-1.8
Verbal and Numeric Reasoning (VNR)	0.5	1.3	2.6	-0.6	-1.0	-1.6
Smoking Status	0.5	1.2	2.1	-1.5	0.8	-0.9
Type 2 Diabetes (T2D) (2018)	0.5	1.0	1.8	0.2	-1.0	-1.4
Medication: Metformin	0.5	0.7	1.7	-1.3	0.1	-0.6
Townsend deprivation index at recruitment	0.5	0.7	2.0	0.0	-0.2	-1.4
Bilateral oophorectomy (both ovaries removed)	0.5	0.6	1.0	1.0	0.4	-0.7
Stomach or abdominal pain in last month	0.5	0.6	0.9	-0.9	0.5	-1.0
Medication: Levothyroxine sodium	0.5	0.9	2.6	1.6	-0.3	0.3
Medication: Ramipril	0.5	0.6	1.3	-0.7	-0.1	-1.1
Medication: Simvastatin	0.5	0.7	1.3	-1.1	-0.4	-0.9
Noisy workplace	0.5	0.6	1.0	-0.8	0.3	1.0
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.7	1.6	-0.5	-1.2	0.5
Prospective memory result	0.5	0.6	0.9	0.9	0.2	0.9
Illnesses of mother	0.5	0.6	1.3	0.7	1.1	0.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.8	1.4	-1.2	-0.1	1.0
Glaucoma (self-reported)	0.5	0.6	1.0	-0.9	-1.0	0.4
Birth weight	0.5	1.2	3.3	0.1	-0.5	1.8
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.7	1.1	-0.7	1.1	0.6
Pulse rate, automated reading	0.5	1.6	2.7	1.4	0.1	1.6
Family relationship satisfaction	0.5	0.7	1.7	1.3	-0.5	0.3
Long-standing illness, disability or infirmity	0.5	0.8	1.7	-0.8	-1.3	-0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.6	0.9	0.7	0.6	0.9
Eye problems/disorders: Glaucoma	0.5	0.5	1.4	-0.4	-1.2	0.1
High cholesterol (Self-reported)	0.5	0.9	1.5	-1.2	-1.0	-0.2
Medication: Atorvastatin	0.5	0.6	1.5	-0.3	0.4	-1.2
Number of operations (self-reported)	0.5	0.8	2.4	1.5	0.1	0.0
Risk taking	0.5	0.7	1.9	0.3	1.4	0.5
Arm predicted mass (left)	0.5	2.3	4.3	-2.1	-1.5	0.5
Intelligence (Savage-Jansen 2018)	0.4	1.3	1.9	-0.5	-1.3	-1.4
Mean Putamen Volume	0.4	0.4	1.0	-0.4	0.3	1.0
Schizophrenia (2014)	0.4	0.9	1.7	-0.9	-1.3	-0.3
Waist Hip Ratio (WHR)	0.4	2.0	4.6	2.2	1.1	0.2
Systolic Blood Pressure	0.4	1.8	5.3	-0.2	0.4	-2.3
Neuroticism	0.4	1.1	1.9	-0.8	0.8	1.4
Ever used hormone-replacement therapy (HRT)	0.4	0.5	1.1	1.1	0.5	0.1
Sitting height	0.4	3.2	6.2	0.7	-2.5	1.7
Hip circumference	0.4	1.9	2.2	-1.2	-1.4	1.5
Time employed in main current job	0.4	0.4	1.2	-1.1	-0.1	-0.3
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.4	0.8	0.9	0.2	0.7
Exposure to tobacco smoke at home	0.4	0.5	1.0	0.3	-0.5	-1.0
Tense / ‘highly strung’	0.4	0.7	1.7	0.7	-1.3	0.3
Hair/balding pattern: Pattern 4	0.4	1.1	2.3	-0.5	-1.5	-0.8
Peak expiratory flow (PEF)	0.4	0.8	1.9	1.4	-0.2	0.8
Ever highly irritable/argumentative for 2 days	0.4	0.5	1.4	-0.4	0.1	-1.2
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	1.4	1.2	0.6	-0.5
Migraine (self-reported)	0.4	0.5	0.9	0.9	0.6	-0.3
Leg fat-free mass (right)	0.4	1.9	4.9	-0.8	-2.2	0.5
Qualifications: nursing, teaching	0.4	0.5	1.3	-1.1	0.3	0.6
Commuting to job workplace: Walk	0.4	0.4	1.0	1.0	0.4	-0.0
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	1.2	-1.1	-0.2	0.8
Illnesses of father: None of the above (group 1)	0.4	0.5	0.6	0.7	0.8	0.7
Number of self-reported non-cancer illnesses	0.4	0.8	2.2	0.0	-1.5	0.1
Ever smoked	0.4	0.8	2.0	-1.4	-0.6	-0.0
Arm fat-free mass (left)	0.4	2.0	3.3	-1.8	-1.6	0.2
Age started oral contraceptive pill	0.4	0.6	1.4	-1.2	0.1	-0.5
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	0.9	-1.0	-0.4	-0.7
Bipolar Disorder (2018)	0.3	0.4	1.1	-1.0	0.0	-0.5
Bipolar Disorder or Schizophrenia	0.3	0.7	1.2	-1.1	-0.9	-0.5
Schizophrenia (2018)	0.3	0.7	1.6	-0.6	-1.3	-0.1
Age at First Birth	0.3	0.5	1.4	0.3	1.2	-0.0
Coronary Artery Disease (CAD)	0.3	0.4	1.2	-0.2	0.0	1.1
LDL Cholesterol	0.3	0.4	0.7	-0.2	-0.7	0.8
Primary Biliary Cirrhosis	0.3	0.4	1.1	-1.0	0.3	-0.2
Blood Eosinophil Count	0.3	2.6	7.3	-0.6	-2.7	-0.3
Lung FVC	0.3	1.5	3.4	-1.9	0.3	1.0
Average weekly spirits intake	0.3	0.4	1.0	1.0	-0.5	0.1
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	0.8	-0.5	-0.2	0.9
Diabetes (mother)	0.3	0.4	1.0	-0.4	-0.3	-1.0
Neuroticism score	0.3	0.6	1.1	-0.7	-0.3	1.0
Trunk fat-free mass	0.3	2.0	2.9	-1.7	-1.7	0.3
Hair/balding pattern: Pattern 3	0.3	0.5	0.7	-0.8	-0.6	0.5
Trunk predicted mass	0.3	1.9	2.8	-1.7	-1.7	0.3
Headache pain in last month	0.3	0.6	0.7	0.8	-0.9	0.6
Hypothyroidism/myxoedema (self-reported)	0.3	0.7	1.6	1.3	-0.7	0.1
Age at first live birth	0.3	0.5	1.4	1.2	-0.1	0.0
Comparative height size at age 10	0.3	1.5	2.7	-1.6	-1.3	0.3
Number of full sisters	0.3	0.3	0.5	0.2	-0.7	0.7
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.4	0.9	0.3	0.5	-1.0
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	0.9	1.0	0.1	0.4
Whole body fat-free mass	0.3	1.7	2.7	-1.4	-1.7	0.3
Whole body water mass	0.3	1.9	3.2	-1.5	-1.8	0.2
Leg predicted mass (right)	0.3	1.9	4.8	-0.8	-2.2	0.4
Ever taken oral contraceptive pill	0.3	0.4	0.6	0.8	-0.6	-0.2
Mother’s age at death	0.3	0.4	0.9	1.0	0.2	0.5
Illnesses of father: High blood pressure	0.3	0.4	1.0	-0.5	-1.0	-0.1
Basal metabolic rate	0.3	1.5	2.9	-1.2	-1.7	0.4
Leg fat percentage (left)	0.3	1.0	2.8	-1.7	-0.3	-0.1
Ever depressed for a whole week	0.3	0.4	0.8	-0.1	0.6	0.9
Pack years of smoking	0.3	0.5	1.4	-1.2	-0.1	0.3
Leg fat mass (left)	0.3	1.1	2.5	-1.6	-0.9	0.4
Worry (Nagel 2018)	0.2	0.5	1.3	-0.1	-1.2	0.5
Crohns Disease (2017)	0.2	0.4	1.1	0.3	0.1	-1.1
Fasting Glucose	0.2	0.3	0.6	0.2	-0.8	-0.5
Blood Red Count	0.2	2.4	6.7	2.6	0.3	0.6
BMI	0.2	1.0	1.7	-1.3	-1.1	0.0
Chronotype (morning person)	0.2	0.5	0.9	-0.7	-1.0	-0.2
Pack years adult smoking proportion	0.2	0.4	1.1	-1.1	-0.2	-0.0
Leg fat-free mass (left)	0.2	1.1	2.4	-0.8	-1.6	0.4
Taking other prescription medications	0.2	0.3	0.4	0.4	-0.5	0.6
Leg predicted mass (left)	0.2	1.2	2.7	-0.9	-1.6	0.3
Waist circumference	0.2	0.6	1.3	-1.1	-0.6	0.4
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.4	0.8	0.2	-0.9	-0.6
Qualifications: None of the above	0.2	0.5	1.4	0.0	-1.2	0.2
Weight	0.2	0.9	1.3	-1.1	-1.2	0.6
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.3	0.7	0.3	-0.8	-0.4
Falls in the last year	0.2	0.3	0.7	0.3	0.2	-0.8
Number of live births	0.2	0.2	0.3	-0.5	-0.5	0.4
Qualifications: A levels/AS levels or equivalent	0.2	0.4	1.2	0.0	-0.2	1.1
Mouth/teeth dental problems: Dentures	0.2	0.3	0.6	-0.3	-0.5	-0.8
Depression (self-reported)	0.2	0.2	0.6	0.8	0.3	0.2
Gout (self-reported)	0.2	0.3	0.6	-0.3	-0.4	0.7
Leg fat percentage (right)	0.2	0.7	2.0	-1.4	0.3	0.0
Mouth/teeth dental problems: Loose teeth	0.2	0.3	0.6	0.4	0.1	0.8
Medication: Ibuprofen	0.2	0.2	0.5	-0.0	-0.7	0.5
Medication: Seretide 50 evohaler	0.2	0.2	0.4	0.6	-0.4	-0.3
Leg fat mass (right)	0.2	0.9	2.0	-1.4	-0.6	0.5
Back pain experienced in last month	0.2	0.3	0.7	0.8	0.4	0.4
Breast cancer (self-reported)	0.2	0.2	0.3	-0.4	0.6	-0.3
Medication: Gliclazide	0.2	0.3	0.5	0.7	-0.5	-0.2
Guilty feelings	0.2	0.3	0.6	-0.6	0.8	-0.1
Irritability	0.2	0.3	0.7	-0.1	0.2	0.8
Myopia	0.2	0.3	0.7	0.8	0.3	-0.2
Depressed Affect (Nagel 2018)	0.1	0.1	0.3	-0.2	-0.6	-0.1
Neuroticism (Nagel 2018)	0.1	0.2	0.5	-0.4	0.7	0.1
Breast Cancer	0.1	0.1	0.3	-0.2	-0.3	0.6
Body Mass Index (BMI) (2010)	0.1	0.1	0.2	-0.2	0.0	-0.5
Crohns Disease (2012)	0.1	0.1	0.2	0.4	0.0	-0.4
HDL Cholesterol	0.1	0.2	0.4	-0.3	0.4	0.6
Rheumatoid Arthritis	0.1	0.1	0.2	-0.2	0.1	-0.4
Blood White Count	0.1	0.8	1.3	-0.5	-1.1	0.9
Heel T-Score	0.1	0.9	2.1	-0.3	0.6	-1.5
Hypothyroidism (self reported)	0.1	0.3	0.7	0.8	-0.3	-0.1
Lung FEV1/FVC ratio	0.1	0.6	1.3	1.2	0.1	0.7
Trunk fat percentage	0.1	0.3	0.6	0.8	-0.1	0.7
Maternal smoking around birth	0.1	0.1	0.1	-0.4	0.2	0.3
Fed-up feelings	0.1	0.2	0.3	-0.4	-0.6	0.3
Trunk fat mass	0.1	0.4	0.6	0.3	-0.7	0.8
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.2	0.5	-0.4	-0.7	-0.2
Medication: Cholesterol lowering	0.1	0.1	0.2	-0.4	0.3	-0.2
Arm fat mass (right)	0.1	0.2	0.4	-0.6	-0.6	0.0
Qualifications: College or University degree	0.1	0.4	0.7	-0.6	0.9	-0.1
Whole body fat mass	0.1	0.4	0.8	0.1	-0.9	0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.2	0.3	0.6	-0.3	-0.3
Arm fat mass (left)	0.1	0.3	0.5	-0.7	-0.6	0.1
Miserableness	0.1	0.2	0.3	-0.5	-0.5	0.1
Pain type(s) experienced in last month: Hip pain	0.1	0.1	0.3	0.5	0.0	-0.4
Diastolic blood pressure, automated reading	0.1	0.3	0.5	0.1	0.6	-0.7
Basal cell carcinoma (self-reported)	0.1	0.2	0.4	-0.0	0.6	0.3
Heart disease (siblings)	0.1	0.1	0.4	-0.6	0.1	0.2
Schizophrenia vs Biploar Disorder	0.0	0.0	0.1	0.3	0.0	0.1
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0
Blood Platelet Count	0.0	0.3	0.5	0.5	-0.7	0.3
Hair Pigment	0.0	1.1	2.7	-0.1	0.9	1.6
Tanning	0.0	0.2	0.4	0.1	0.1	0.7
Heel bone mineral density (BMD) T-score, automated (left)	0.0	0.1	0.2	-0.3	0.1	0.4
Arm fat percentage (right)	0.0	0.0	0.1	-0.3	0.1	0.0
Body fat percentage	0.0	0.1	0.2	0.2	-0.2	0.4
Arm fat percentage (left)	0.0	0.0	0.1	-0.3	-0.0	-0.0
Loneliness, isolation	0.0	0.0	0.1	0.1	0.3	0.2

Hub : Genes

DLGAP1-AS2

Models

Trait associations