TWAS hub - DMTF1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.160	0.0520	0.00021	0.022	NA	0.034	NA	0.008	6.2e-03	NA	8.8e-04	NA	6.2e-02
2	GTEx	Nerve Tibial	0.116	0.0449	0.00250	0.089	NA	0.074	NA	0.093	7.2e-07	NA	6.6e-06	NA	4.2e-07
3	TCGA	Stomach Adenocarcinoma	0.083	0.0470	0.00470	0.020	0.052	0.016	NA	0.016	1.4e-02	0.00012	2.2e-02	NA	2.4e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Pain all over the body in last month	4.9	5.2	10.2	-3.2	-2.3	-0.1
Bipolar Disorder or Schizophrenia	4.1	10.0	27.8	1.3	-0.8	5.3
Schizophrenia (2018)	3.8	7.9	21.3	0.9	-1.2	4.6
Major Depression (MDD)	3.8	4.6	9.4	2.0	3.1	0.6
Medication: Gliclazide	3.8	4.3	7.4	2.3	2.7	-0.2
Financial situation satisfaction	3.8	4.7	5.6	-2.2	-2.4	1.9
Pain experienced in last month	3.7	6.1	11.6	1.6	2.1	-3.4
Back pain experienced in last month	3.6	5.3	13.2	-0.4	-1.6	3.6
Schizophrenia (2014)	3.3	7.2	20.0	0.4	-1.2	4.5
Bipolar Disorder (2011)	3.1	3.0	5.8	1.3	1.3	2.4
Stomach or abdominal pain in last month	3.0	3.7	9.1	1.4	0.2	3.0
Prostate Cancer	2.9	4.1	8.9	-1.7	-0.7	-3.0
Hair/balding pattern: Pattern 4	2.6	6.2	10.2	-2.9	-3.2	-0.4
Family relationship satisfaction	2.6	3.2	5.7	-1.4	-1.4	2.4
Supplements: Calcium	2.6	2.9	5.9	-0.9	-2.4	1.4
Diabetes (father)	2.4	3.0	8.1	-2.9	-0.9	-0.4
Eye problems/disorders: Cataract	2.4	2.8	3.5	-1.8	-1.3	-1.9
Bilateral oophorectomy (both ovaries removed)	2.3	2.7	6.1	1.2	0.7	2.5
Qualifications: nursing, teaching	2.3	3.5	4.9	2.2	2.2	-1.0
Myopia	2.3	3.4	6.4	1.9	2.5	-0.2
Ever taken oral contraceptive pill	2.2	2.4	4.5	-0.7	-1.5	2.1
Lupus	2.1	3.2	8.9	0.8	0.3	3.0
Frequency of unenthusiasm / disinterest in last 2 weeks	2.1	2.9	4.1	-1.3	-1.7	2.0
Depression (self-reported)	2.1	2.5	6.4	-2.5	-1.0	0.2
Unable to work because of sickness or disability	2.1	2.7	3.6	-1.2	-1.8	1.9
Alzheimer’s Disease (in father)	2.0	2.2	5.3	1.1	0.1	2.3
Hair/balding pattern: Pattern 3	2.0	3.0	5.0	1.9	2.2	-0.5
Medication: Ibuprofen	2.0	2.4	3.5	-1.8	-0.8	1.9
Tinnitus: Yes, but not now, but have in the past	1.9	2.0	3.5	-1.1	-1.2	1.9
Medication: Atenolol	1.9	2.3	6.0	0.3	1.0	-2.4
Mouth/teeth dental problems: Dentures	1.9	3.3	4.8	2.1	2.2	-0.8
High blood pressure (siblings)	1.9	2.7	4.2	1.9	2.1	0.6
Ever depressed for a whole week	1.9	2.3	4.3	1.1	1.2	2.1
Fasting Glucose	1.8	2.1	5.2	1.0	0.3	2.3
Ever had hysterectomy (womb removed)	1.8	2.0	3.2	-1.4	-1.8	0.9
Number of children fathered	1.8	2.1	3.5	-1.9	-1.5	-0.7
Bipolar Disorder (2018)	1.7	2.6	7.1	0.9	0.2	2.7
Long-standing illness, disability or infirmity	1.7	2.7	3.9	-1.5	-1.4	2.0
Ovarian Cancer	1.6	2.1	4.3	-1.4	0.5	-2.1
Heart attack	1.6	2.0	4.8	-2.2	-0.9	-0.7
Illnesses of siblings	1.6	2.3	2.7	-1.6	-1.6	-1.3
Ever had stillbirth, spontaneous miscarriage or termination	1.6	1.7	2.9	-0.5	-1.4	1.7
Alzheimer’s Disease (including proxy)	1.5	2.1	5.2	1.1	-0.2	2.3
Coronary Artery Disease (CAD)	1.5	1.7	3.5	-1.9	-1.0	0.9
Multivitamins +/- minerals	1.4	1.8	3.3	-1.8	-0.9	-1.1
Hair/balding pattern: Pattern 2	1.4	1.7	2.8	0.6	-1.4	1.7
Worrier / anxious feelings	1.4	2.6	6.3	0.4	2.5	-1.1
Number of full brothers	1.4	1.8	3.2	0.0	-1.8	1.5
Heart attack/myocardial infarction (self-reported)	1.4	1.8	4.4	-2.1	-1.0	-0.2
Falls in the last year	1.3	1.8	3.8	-2.0	-0.8	0.9
Headache pain in last month	1.3	2.2	3.4	-1.0	-1.8	1.5
Migraine (self-reported)	1.3	1.7	4.2	-0.9	-0.2	-2.1
Handedness (chirality/laterality): Left-handed	1.3	1.6	4.1	-0.3	-0.8	2.0
Crohns Disease (2017)	1.2	2.5	7.4	0.3	-0.3	2.7
Diabetes (mother)	1.2	1.5	2.1	-1.4	-0.8	1.3
Mouth/teeth dental problems: Loose teeth	1.2	1.4	2.6	-0.6	-1.1	1.6
Emphysema/chronic bronchitis	1.2	1.4	2.7	1.1	0.4	1.6
Average weekly champagne plus white wine intake	1.2	1.6	2.9	0.2	-1.4	1.7
Tinnitus: Yes, now most or all of the time	1.2	1.4	3.0	0.3	1.7	-1.1
Ever had prostate specific antigen (PSA) test	1.2	1.4	2.9	-0.3	1.0	-1.7
Medication: Omeprazole (e.g. Zanprol)	1.2	1.5	2.8	0.8	1.7	1.0
Primary Biliary Cirrhosis	1.1	1.6	3.9	1.0	-0.0	2.0
Cardiovascular Disease	1.1	3.6	7.0	-2.6	-1.6	-1.1
Had other major operations	1.1	1.3	3.6	-0.4	-0.5	1.9
Mouth/teeth dental problems	1.1	1.6	2.5	-1.4	-1.6	0.8
Gout (self-reported)	1.1	1.5	1.9	-1.1	-1.2	1.4
Illnesses of father: Heart disease	1.1	1.5	3.9	0.5	0.6	-2.0
Commuting to job workplace: Cycle	1.1	1.3	2.9	-1.0	-0.3	-1.7
Other serious medical condition/disability diagnosed by doctor	1.0	1.3	2.9	-0.3	-1.0	1.7
Eye problems/disorders: Diabetes related eye disease	1.0	1.1	3.1	-0.4	-0.3	1.8
Medication for hormone replacement therapy	1.0	1.1	3.3	-0.0	-0.3	1.8
Townsend deprivation index at recruitment	1.0	1.5	1.8	-1.1	-1.3	1.1
Supplements: Glucosamine	1.0	1.2	2.8	-1.7	-0.8	-0.5
Pulse wave reflection index	1.0	1.2	2.5	-1.1	-1.6	0.0
Mouth/teeth dental problems: Bleeding gums	1.0	1.3	2.2	1.5	0.9	0.9
Exposure to tobacco smoke outside home	1.0	1.3	2.7	1.6	1.1	-0.0
Reason for reducing amount of alcohol drunk: Health precaution	1.0	1.1	3.1	0.5	1.8	-0.2
Smoking status: Current	1.0	1.6	2.5	1.5	1.6	0.4
Miserableness	1.0	1.7	3.9	-2.0	-1.0	-0.4
Supplements: Fish oil (including cod liver oil)	1.0	1.4	2.5	-1.6	-1.0	0.8
Alcohol drinker status: Never	1.0	1.2	1.7	0.9	1.1	1.3
Schizophrenia vs Biploar Disorder	0.9	1.2	2.4	-1.5	-0.8	-0.9
Average weekly spirits intake	0.9	1.1	1.6	-0.1	-1.3	-1.2
Severe depression (siblings)	0.9	1.0	1.9	1.0	0.3	1.4
Fed-up feelings	0.9	1.6	3.2	-1.8	-1.3	0.1
Hayfever, allergic rhinitis or eczema	0.9	1.9	5.4	0.3	-0.4	2.3
Impedance of leg (left)	0.9	4.4	9.7	-0.3	-1.8	3.1
Hearing difficulty/problems with background noise	0.9	1.4	3.7	-1.9	-0.8	0.3
Ever unenthusiastic/disinterested for a whole week	0.9	1.2	3.2	-0.5	0.1	1.8
Financial difficulties in last 2 years	0.9	1.3	1.9	-1.1	-1.4	0.9
Lung cancer (father)	0.9	1.1	2.0	1.4	0.5	-1.0
Angina (self-reported)	0.9	1.2	2.6	0.2	1.6	-1.0
HDL Cholesterol	0.8	1.3	1.8	-1.4	-0.4	-1.4
Angina	0.8	1.1	1.8	-0.2	1.3	-1.2
Medication: Co-codamol	0.8	0.9	2.4	-1.5	-0.2	0.7
Current tobacco smoking	0.8	1.3	2.2	1.4	1.5	0.2
Hayfever/allergic rhinitis (self-reported)	0.8	1.0	2.2	0.4	-0.8	1.5
Alcohol intake versus 10 years previously	0.8	1.2	1.8	1.4	1.1	0.8
Frequency of tiredness / lethargy in last 2 weeks	0.8	1.3	3.3	-0.7	-0.3	1.8
Qualifications: A levels/AS levels or equivalent	0.8	1.8	3.9	2.0	1.1	-0.5
Breastfed as a baby	0.8	1.0	2.0	-1.4	-0.9	-0.6
Wheeze or whistling in the chest in last year	0.8	1.4	2.1	-0.9	-1.1	1.5
Neck or shoulder pain in last month	0.8	1.2	2.0	-1.1	-0.6	1.4
Medication: Allopurinol	0.8	1.0	1.5	-0.9	-0.9	1.2
Chest pain or discomfort	0.8	1.2	2.5	-0.7	-0.8	1.6
Mineral and other dietary supplements	0.8	1.1	2.3	1.5	1.0	0.4
Breast cancer (self-reported)	0.8	1.0	2.3	-1.5	-0.6	-0.4
Irritable Bowel Disease (IBD)	0.7	1.6	4.5	0.3	0.3	2.1
Lung FVC	0.7	3.5	7.0	2.6	1.7	-0.8
Diabetes (self-reported)	0.7	1.1	1.5	0.8	1.0	1.2
Medication: Omeprazole	0.7	0.9	1.2	0.5	1.1	1.1
Heart disease (mother)	0.7	0.9	1.8	0.1	0.9	1.4
Number of full sisters	0.7	0.9	1.5	1.2	-0.2	1.1
Leg pain on walking	0.7	0.9	1.4	1.0	0.4	1.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.7	0.8	2.5	-0.1	0.2	1.6
Medication: Aspirin	0.7	0.9	2.0	-0.5	-0.6	1.4
Guilty feelings	0.7	1.0	2.7	-0.3	1.7	0.5
Wears glasses or contact lenses	0.7	0.8	1.3	0.0	1.0	-1.2
Commuting to job workplace: Public transport	0.7	0.8	1.3	1.1	1.1	-0.2
Risk taking	0.7	1.0	1.6	0.9	0.7	1.3
Age started oral contraceptive pill	0.7	0.8	1.6	0.1	1.0	-1.2
Impedance of whole body	0.7	3.4	9.0	0.5	-0.9	3.0
Depressed Affect (Nagel 2018)	0.6	1.2	1.9	-1.3	-1.4	-0.1
Breast Cancer	0.6	1.4	2.6	-1.3	-0.1	1.6
Rheumatoid Arthritis	0.6	0.8	2.2	-0.3	-0.1	1.5
Smoking Status	0.6	1.5	3.1	1.8	1.1	-0.2
Frequency of depressed mood in last 2 weeks	0.6	0.8	2.2	-0.3	-0.4	1.5
Vitamin and mineral supplements	0.6	0.8	1.6	1.3	0.4	0.8
Impedance of leg (right)	0.6	3.1	6.0	-0.5	-1.7	2.4
Maternal smoking around birth	0.6	0.9	2.2	0.4	-0.5	1.5
Frequency of tenseness / restlessness in last 2 weeks	0.6	1.0	1.5	0.2	-1.2	1.2
Happiness	0.6	0.8	1.3	-1.1	0.0	1.0
Impedance of arm (left)	0.6	2.8	6.9	0.9	-0.8	2.6
Birth weight of first child	0.6	1.0	1.2	0.9	1.0	-1.1
Hypothyroidism/myxoedema (self-reported)	0.6	1.1	1.5	-1.1	-1.2	-0.8
Health satisfaction	0.6	0.8	2.4	0.1	1.6	0.1
Medication: Blood pressure	0.6	1.0	2.4	-1.6	0.1	-0.7
Illness, injury, bereavement, stress in last 2 years	0.6	0.7	1.0	0.7	1.0	-0.8
Irritability	0.6	1.0	2.2	-1.5	0.1	-0.8
Worry (Nagel 2018)	0.5	1.0	1.1	-1.0	1.1	-1.0
Verbal and Numeric Reasoning (VNR)	0.5	1.1	2.5	0.9	-0.3	-1.6
HbA1C	0.5	0.6	1.3	-0.4	-1.2	0.6
Neuroticism (2016)	0.5	0.7	0.9	0.8	0.9	0.7
Triglycerides	0.5	0.8	2.3	0.3	0.1	1.5
Height	0.5	8.8	14.3	3.8	2.4	2.5
Lung FEV1/FVC ratio	0.5	2.7	5.7	2.4	1.1	1.2
Neuroticism	0.5	1.1	2.6	-1.6	-0.3	-0.8
Average weekly fortified wine intake	0.5	0.6	1.0	-0.5	-0.7	1.0
Age when periods started (menarche)	0.5	1.2	1.6	1.2	1.2	-0.8
Allergy	0.5	1.3	3.6	-0.0	0.4	-1.9
Medication: Ramipril	0.5	0.7	1.1	0.8	0.4	-1.1
Medication: Simvastatin	0.5	0.7	2.0	-1.4	-0.0	-0.4
Fluid intelligence score	0.5	0.9	1.6	0.1	-1.3	-1.1
Impedance of arm (right)	0.5	2.2	5.9	0.8	-0.1	2.4
Time employed in main current job	0.5	0.6	1.8	-0.2	0.2	-1.4
Father’s age at death	0.5	0.6	1.5	-0.6	0.1	1.2
Number of live births	0.5	0.8	1.4	1.2	-0.1	0.9
Prospective memory result	0.5	0.7	1.8	-0.2	1.4	0.3
Ever highly irritable/argumentative for 2 days	0.5	0.5	1.1	-0.3	-0.6	1.1
Loud music exposure frequency	0.5	0.6	1.0	-1.0	-0.8	0.3
Chronic bronchitis/emphysema (mother)	0.5	0.6	1.0	-0.1	1.0	-0.9
Eye problems/disorders: None of the above	0.5	0.6	1.2	0.7	1.1	-0.3
Average weekly red wine intake	0.5	0.7	1.1	0.7	0.7	-1.0
Mood swings	0.5	0.8	1.4	-1.0	-1.2	-0.0
Friendships satisfaction	0.5	0.6	0.8	-0.9	-0.8	0.5
Medication for cholesterol	0.5	0.7	1.3	1.1	0.7	-0.6
Illnesses of father: None of the above (group 1)	0.5	0.6	1.0	0.6	1.0	0.6
Depression (Nagel 2018)	0.4	0.6	1.7	-0.2	0.0	1.3
Intelligence (Savage-Jansen 2018)	0.4	1.3	2.5	0.4	-1.2	-1.6
Age at First Birth	0.4	0.6	1.7	-0.0	0.0	-1.3
Blood Platelet Count	0.4	4.8	8.2	-2.9	-1.9	-1.6
Waist Hip Ratio (WHR)	0.4	1.6	3.4	0.8	0.9	1.9
Pack years adult smoking proportion	0.4	0.6	1.1	1.0	0.8	-0.3
Qualifications: CSEs or equivalent	0.4	0.5	0.8	-0.9	-0.4	-0.7
Pulse rate	0.4	0.6	1.4	0.6	1.2	-0.3
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.6	1.6	-1.3	-0.1	0.3
Medication: Cholesterol lowering	0.4	0.7	1.8	0.1	1.3	-0.5
Medication: Lansoprazole	0.4	0.5	1.4	-1.2	0.1	0.2
Exposure to tobacco smoke at home	0.4	0.5	0.9	0.6	-0.4	0.9
Qualifications: O levels/GCSEs or equivalent	0.4	0.6	1.2	0.6	1.1	-0.3
Comparative body size at age 10	0.4	1.0	2.2	-1.5	-0.9	-0.1
Qualifications: College or University degree	0.4	1.4	3.9	0.4	-0.1	-2.0
Medication for pain relief, constipation, heartburn	0.4	0.6	0.9	0.3	-1.0	-1.0
Suffer from ‘nerves’	0.4	0.7	1.9	0.2	1.4	0.1
Overall health rating	0.4	0.8	1.4	-1.0	0.0	1.2
Age at last live birth	0.4	0.6	1.0	0.3	0.9	1.0
Supplements: Vitamin C	0.4	0.4	0.6	-0.5	-0.8	0.6
Knee pain experienced in last month	0.4	0.5	1.1	-1.0	-0.5	0.5
Hypertension (Self-reported)	0.4	1.1	2.3	-1.5	-0.9	-0.5
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.8	1.6	-0.0	-1.3	0.9
Loneliness, isolation	0.4	0.6	1.1	-0.8	-1.0	-0.1
Ever had bowel cancer screening	0.4	0.5	0.7	-0.8	0.7	0.6
Diabetes diagnosed by doctor	0.4	0.7	1.8	0.4	0.4	1.3
Commuting to job workplace: Walk	0.4	0.4	0.9	0.5	-0.3	1.0
Osteoarthritis (self-reported)	0.4	0.5	1.2	0.1	-0.6	1.1
Eye problems/disorders: Glaucoma	0.4	0.4	0.9	0.3	-1.0	0.6
Pain type(s) experienced in last month: Hip pain	0.4	0.5	1.1	-0.5	1.1	0.1
Medication: Atorvastatin	0.4	0.5	0.8	-0.3	0.9	-0.8
Ever smoked	0.4	0.8	2.1	1.5	0.4	0.3
Fractured/broken bones in last 5 years	0.4	0.5	0.8	0.4	0.9	0.7
Vascular/heart problems diagnosed by doctor	0.4	1.2	2.4	1.6	0.8	0.7
Cholesterol lowering medication	0.4	0.5	1.5	-1.2	0.3	-0.2
Basal cell carcinoma (self-reported)	0.4	0.5	1.1	1.1	0.6	-0.2
Heart disease (siblings)	0.4	0.4	0.9	-0.6	-0.2	1.0
Pack years of smoking	0.4	0.6	1.0	1.0	0.9	-0.1
Alzheimer’s Disease (in mother)	0.3	0.3	0.6	0.8	0.1	0.6
Type 2 Diabetes (T2D) (2012)	0.3	0.3	0.4	0.3	-0.6	0.7
Allergy or Eczema	0.3	0.8	2.5	0.2	-0.1	1.6
Hypothyroidism (self reported)	0.3	0.6	1.5	-0.5	-0.1	-1.2
Type 2 Diabetes (T2D) (2018)	0.3	0.6	1.5	-0.3	-0.5	1.2
Hand grip strength (left)	0.3	0.8	1.7	-0.6	-1.3	-0.6
Number of treatments/medications taken	0.3	0.6	0.9	-1.0	-0.3	0.9
Systolic blood pressure, automated reading	0.3	1.0	1.8	1.3	1.0	0.2
Supplements: Zinc	0.3	0.4	0.8	0.6	0.9	-0.1
High blood pressure	0.3	0.8	1.8	-1.4	-0.6	-0.3
Chronic bronchitis/emphysema (father)	0.3	0.4	0.8	0.9	0.3	-0.5
High blood pressure (mother)	0.3	0.4	0.9	0.2	0.6	-0.9
Qualifications: None of the above	0.3	0.7	1.5	-0.7	-0.4	1.2
Hip circumference	0.3	1.1	3.0	-0.5	-1.7	-0.2
Forced expiratory volume in 1-second (FEV1)	0.3	1.0	2.4	1.5	-0.6	0.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	0.8	2.5	1.6	-0.3	0.1
Peak expiratory flow (PEF)	0.3	0.6	1.7	-0.0	-1.3	0.4
Medication: Paracetamol	0.3	0.5	1.1	-0.6	1.1	0.2
Pulse rate, automated reading	0.3	1.0	1.5	1.2	1.1	0.5
Had major operations	0.3	0.3	0.5	-0.7	0.3	-0.7
Medication: Aspirin	0.3	0.5	1.3	-0.2	-0.3	1.1
Illnesses of siblings: Diabetes	0.3	0.3	0.6	-0.3	0.5	0.8
Mouth/teeth dental problems: Mouth ulcers	0.3	0.5	1.5	-1.2	-0.3	-0.1
Hearing aid user	0.3	0.4	1.0	-1.0	0.3	-0.3
Medication: Paracetamol	0.3	0.5	1.1	-0.6	1.0	0.1
Medication: Lisinopril	0.3	0.4	0.9	-0.2	1.0	-0.5
Illnesses of father: High blood pressure	0.3	0.4	0.9	0.0	-0.3	-1.0
Neuroticism (Nagel 2018)	0.2	0.6	1.7	-1.3	-0.1	-0.0
Systolic Blood Pressure	0.2	1.2	3.0	0.2	0.8	-1.7
Sensitivity / hurt feelings	0.2	0.3	0.9	0.2	-0.1	0.9
Hearing difficulty/problems: Yes	0.2	0.3	0.4	-0.1	0.6	0.6
Relative age of first facial hair	0.2	0.5	0.9	0.2	0.6	-1.0
Ever used hormone-replacement therapy (HRT)	0.2	0.3	0.8	0.2	0.3	0.9
Trunk fat percentage	0.2	0.6	1.0	1.0	-0.3	0.9
Hand grip strength (right)	0.2	0.5	1.1	0.4	-1.0	0.4
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.5	0.7	-0.9	-0.5	0.6
Serious illness, injury or assault to yourself	0.2	0.2	0.4	-0.4	-0.1	0.7
Alcohol usually taken with meals	0.2	0.2	0.4	0.7	-0.5	0.2
Had menopause	0.2	0.2	0.4	0.1	-0.4	0.6
Forced vital capacity (FVC)	0.2	0.6	0.9	1.0	-0.9	0.4
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	0.3	0.5	-0.4	0.4
Standing height	0.2	2.1	4.6	1.0	-0.9	2.1
Length of working week for main job	0.2	0.2	0.3	0.5	0.4	0.2
Tense / ‘highly strung’	0.2	0.4	0.9	-1.0	-0.2	-0.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.3	0.7	-0.9	-0.1	-0.0
Medication for cholesterol, blood pressure or diabetes	0.2	0.3	0.8	0.9	-0.2	0.3
Glaucoma (self-reported)	0.2	0.3	0.8	0.2	-0.1	-0.9
Medication: Ventolin 100micrograms inhaler	0.2	0.3	0.6	-0.8	-0.1	0.5
Birth weight	0.2	0.4	0.6	-0.5	-0.8	0.5
Forced vital capacity (FVC), Best measure	0.2	0.7	1.1	1.0	-0.9	0.3
Worry too long after embarrassment	0.2	0.4	1.0	0.2	0.4	1.0
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.2	0.4	0.5	-0.2	0.7
Shortness of breath walking on level ground	0.2	0.2	0.4	-0.5	0.3	-0.6
Mean time to correctly identify matches	0.2	0.3	0.6	0.6	0.8	0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.2	0.6	-0.1	-0.7	-0.3
Commuting to job workplace: Car/motor vehicle	0.2	0.2	0.4	-0.4	-0.6	0.2
Smoking status: Previous	0.2	0.2	0.5	0.2	-0.7	-0.4
Osteoporosis (self-reported)	0.2	0.3	0.8	0.3	-0.9	0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.3	0.5	-0.3	-0.7	-0.6
Mother’s age at death	0.2	0.3	0.5	-0.6	-0.3	-0.7
High cholesterol (Self-reported)	0.2	0.3	0.8	-0.3	0.9	-0.2
Number of operations (self-reported)	0.2	0.3	0.5	-0.7	0.1	0.5
Deep venous thrombosis (DVT) (self-reported)	0.2	0.2	0.4	0.4	-0.6	-0.2
Alcohol drinker status: Previous	0.2	0.2	0.5	-0.2	0.2	0.7
Ulcerative Colitis (UC)	0.1	0.3	0.6	-0.1	0.8	0.5
Body Mass Index (BMI) (2010)	0.1	0.2	0.3	-0.5	-0.5	-0.2
Mean Putamen Volume	0.1	0.1	0.2	0.5	0.0	0.1
LDL Cholesterol	0.1	0.2	0.3	-0.1	0.5	0.5
Ulcerative Colitis	0.1	0.2	0.4	-0.7	-0.3	0.4
Blood Red Count	0.1	0.9	1.1	-0.9	-1.0	-1.0
Heel T-Score	0.1	0.7	0.7	-0.8	-0.9	-0.7
BMI	0.1	0.7	1.9	-0.2	-0.0	-1.4
Respiratory disease	0.1	0.2	0.4	-0.3	-0.7	0.4
Chronotype (morning person)	0.1	0.3	0.6	0.1	0.8	-0.5
Tanning	0.1	1.7	2.8	-1.7	-0.4	-1.5
Medication: Metformin	0.1	0.1	0.2	0.0	0.5	0.2
Leg fat-free mass (left)	0.1	0.3	0.8	0.4	0.0	-0.9
Relative age voice broke	0.1	0.1	0.2	0.4	0.3	0.3
Taking other prescription medications	0.1	0.2	0.3	0.5	0.6	-0.0
Diverticular disease/diverticulitis (self-reported)	0.1	0.2	0.4	-0.3	0.1	0.7
Medication: Levothyroxine sodium	0.1	0.2	0.4	0.1	0.1	-0.7
Sitting height	0.1	0.9	1.1	1.0	-0.7	1.1
Body mass index (BMI)	0.1	0.4	1.2	-0.0	0.1	-1.1
Leg predicted mass (left)	0.1	0.3	0.8	0.4	0.0	-0.9
Trunk fat mass	0.1	0.4	0.7	0.8	-0.3	0.6
Past tobacco smoking	0.1	0.2	0.6	-0.8	0.2	0.2
Nervous feelings	0.1	0.1	0.2	-0.5	0.4	-0.1
Neuroticism score	0.1	0.3	0.8	-0.9	0.2	0.3
Noisy workplace	0.1	0.1	0.2	-0.2	-0.0	0.4
Illnesses of mother	0.1	0.2	0.5	-0.0	-0.7	0.2
Blood clot in the leg (DVT)	0.1	0.2	0.4	0.6	-0.3	-0.0
Body fat percentage	0.1	0.2	0.3	0.4	-0.5	0.4
Age at first live birth	0.1	0.1	0.3	-0.5	0.1	0.3
Medication: Seretide 50 evohaler	0.1	0.1	0.1	0.3	0.3	0.2
Whole body fat mass	0.1	0.3	0.4	0.6	-0.4	0.5
Alcohol intake frequency.	0.1	0.3	0.9	-0.0	-0.0	0.9
Comparative height size at age 10	0.1	0.4	0.4	0.5	-0.6	0.7
Qualifications: NVQ or HND or HNC or equivalent	0.1	0.1	0.2	-0.1	-0.3	0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.1	0.3	0.1	0.5	-0.3
Whole body fat-free mass	0.1	0.3	0.9	0.1	-0.1	-1.0
Asthma (self-reported)	0.1	0.1	0.3	-0.5	-0.2	-0.3
Number of self-reported non-cancer illnesses	0.1	0.3	0.5	-0.4	0.4	0.7
Medication: Bendroflumethiazide	0.1	0.2	0.5	-0.2	-0.7	-0.2
Leg fat percentage (left)	0.1	0.3	0.5	0.3	-0.6	0.7
Average weekly beer plus cider intake	0.1	0.2	0.4	0.3	0.6	0.1
Diastolic blood pressure, automated reading	0.1	0.2	0.4	0.7	0.0	-0.3
Reaction Time	0.0	0.1	0.1	0.4	-0.2	0.3
Crohns Disease (2012)	0.0	0.1	0.1	0.2	-0.2	0.3
Blood Eosinophil Count	0.0	0.3	0.4	-0.7	-0.1	-0.7
Blood White Count	0.0	0.4	1.0	0.2	1.0	0.3
Hair Pigment	0.0	0.9	1.3	-0.1	-1.1	1.1
Waist circumference	0.0	0.1	0.2	0.3	-0.2	0.5
Number of incorrect matches in round	0.0	0.0	0.1	-0.2	0.1	0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.0	0.0	0.1	-0.3	-0.2	0.1
Weight	0.0	0.1	0.2	0.3	-0.4	-0.1
Arm fat percentage (right)	0.0	0.1	0.2	0.4	0.3	-0.3
Trunk fat-free mass	0.0	0.2	0.7	0.1	-0.1	-0.9
Asthma	0.0	0.1	0.2	-0.4	-0.1	-0.3
Pulse wave Arterial Stiffness index	0.0	0.1	0.1	0.0	-0.2	0.4
Arm fat mass (right)	0.0	0.1	0.3	0.5	0.2	-0.3
Trunk predicted mass	0.0	0.3	0.7	0.0	-0.1	-0.9
Medication: Amlodipine	0.0	0.1	0.1	0.1	-0.3	-0.3
Leg fat percentage (right)	0.0	0.2	0.5	0.1	-0.7	0.2
Arm fat-free mass (right)	0.0	0.2	0.5	0.1	-0.5	-0.7
Pulse wave peak to peak time	0.0	0.0	0.0	-0.1	-0.0	-0.1
Leg fat mass (right)	0.0	0.2	0.4	0.1	-0.7	-0.1
Arm predicted mass (right)	0.0	0.2	0.3	0.3	-0.4	-0.5
Leg fat-free mass (right)	0.0	0.3	0.5	0.5	0.1	-0.7
Arm fat percentage (left)	0.0	0.1	0.3	0.5	-0.0	-0.1
Whole body water mass	0.0	0.3	0.8	0.1	-0.1	-0.9
Leg predicted mass (right)	0.0	0.2	0.4	0.5	0.1	-0.6
Arm fat mass (left)	0.0	0.1	0.2	0.4	-0.1	-0.2
Medication: Blood pressure	0.0	0.0	0.1	0.1	-0.0	-0.3
Basal metabolic rate	0.0	0.2	0.6	0.3	-0.1	-0.8
Arm fat-free mass (left)	0.0	0.2	0.5	0.1	-0.1	-0.7
Leg fat mass (left)	0.0	0.1	0.3	0.2	-0.5	0.2
Arm predicted mass (left)	0.0	0.2	0.4	0.1	-0.3	-0.6

Hub : Genes

DMTF1

Models

Trait associations