TWAS hub - DNAJC28

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.123	0.027	4.4e-11	0.153	0.092	0.137	0.14	0.150	3.9e-18	2.6e-11	2.6e-16	1.2e-16	7.8e-18
2	GTEx	Thyroid	0.092	0.033	1.5e-03	-0.003	NA	0.018	NA	0.003	7.2e-01	NA	1.4e-02	NA	1.8e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Crohns Disease (2017)	6.5	14.2	26.7	5.2	-1.3
Basal cell carcinoma (self-reported)	6.3	7.4	9.9	-2.2	3.2
Diastolic blood pressure, automated reading	6.1	19.0	19.8	-4.3	4.5
Exposure to tobacco smoke outside home	5.5	7.4	7.8	-2.8	2.6
Medication: Levothyroxine sodium	4.8	8.1	15.8	4.0	-0.7
Coronary Artery Disease (CAD)	4.5	5.4	10.2	-0.8	3.2
Pain type(s) experienced in last month: Hip pain	4.5	5.7	7.0	2.6	-2.1
Irritable Bowel Disease (IBD)	4.4	10.5	16.2	4.0	-2.2
Rheumatoid Arthritis	4.4	6.0	11.7	3.4	-0.5
Hypothyroidism/myxoedema (self-reported)	4.2	8.3	15.6	3.9	-1.0
Hypothyroidism (self reported)	4.1	9.5	17.1	4.1	-1.4
Ever had prostate specific antigen (PSA) test	3.8	4.3	6.9	2.6	-1.3
Crohns Disease (2012)	3.7	5.9	10.7	3.3	-1.1
Glaucoma (self-reported)	3.6	4.2	8.2	2.9	-0.4
Major Depression (MDD)	3.2	3.9	7.3	-2.7	-0.7
Number of children fathered	3.2	3.6	6.9	2.6	-0.6
Eye problems/disorders: Glaucoma	3.2	3.7	7.5	2.7	-0.1
Seen doctor (GP) for nerves, anxiety, tension or depression	3.1	4.8	7.7	1.4	-2.8
Medication: Ventolin 100micrograms inhaler	3.0	3.8	7.5	-0.3	-2.7
Back pain experienced in last month	3.0	4.4	8.8	3.0	-0.0
Risk taking	3.0	4.3	5.7	-1.7	2.4
Worrier / anxious feelings	2.9	5.5	7.4	1.9	-2.7
Illnesses of mother	2.8	3.4	5.4	1.2	-2.3
Eye problems/disorders: Cataract	2.7	3.1	5.2	2.3	-1.0
Medication: Amlodipine	2.6	3.6	4.2	-2.1	1.7
Cholesterol lowering medication	2.6	3.9	7.4	-0.6	2.7
Schizophrenia (2018)	2.5	5.1	8.9	-3.0	1.1
Systolic blood pressure, automated reading	2.5	7.2	9.7	-2.2	3.1
Mouth/teeth dental problems	2.5	3.8	6.1	2.5	-1.3
Medication: Aspirin	2.4	3.1	6.1	-0.3	2.5
Cardiovascular Disease	2.3	7.6	11.5	-1.9	3.4
Medication: Ramipril	2.3	3.0	4.2	-2.1	1.3
Pulse wave Arterial Stiffness index	2.3	2.7	4.0	-1.2	2.0
Alzheimer’s Disease (in father)	2.2	2.4	3.6	-1.1	1.9
Other serious medical condition/disability diagnosed by doctor	2.2	2.9	3.7	1.9	1.4
Supplements: Zinc	2.2	2.4	3.6	1.1	-1.9
Townsend deprivation index at recruitment	2.2	3.1	4.8	-2.2	1.2
Medication for cholesterol	2.2	3.3	5.4	1.1	-2.3
Bipolar Disorder or Schizophrenia	2.1	5.1	6.4	-2.5	1.9
Systolic Blood Pressure	2.1	10.3	12.2	-2.9	3.5
Eye problems/disorders: Diabetes related eye disease	2.0	2.2	4.3	2.1	-0.2
Number of full sisters	2.0	2.4	3.0	-1.3	1.7
Serious illness, injury or assault to yourself	1.9	2.3	3.1	-1.8	1.2
Had other major operations	1.9	2.3	4.3	-0.6	2.1
Medication: Ibuprofen (e.g. Nurofen)	1.9	2.4	3.3	1.8	-1.2
Birth weight of first child	1.9	3.4	5.0	1.4	-2.2
Number of full brothers	1.9	2.4	4.6	-2.1	0.4
Loneliness, isolation	1.9	2.6	3.3	1.4	-1.8
Ulcerative Colitis (UC)	1.8	3.4	3.6	1.8	-1.9
Prostate Cancer	1.8	2.5	3.1	-1.4	1.8
Tinnitus: Yes, but not now, but have in the past	1.8	2.0	3.7	-1.9	-0.5
Exposure to tobacco smoke at home	1.8	2.0	3.0	-1.7	-1.0
Medication: Blood pressure	1.8	3.4	5.0	-1.3	2.2
Fasting Glucose	1.5	1.8	2.0	-1.4	1.2
Father’s age at death	1.5	2.0	3.6	0.6	-1.9
Supplements: Calcium	1.5	1.6	1.7	1.3	-1.3
Heel T-Score	1.4	10.8	18.6	1.8	-4.3
Frequency of depressed mood in last 2 weeks	1.4	2.0	4.0	0.2	-2.0
Bilateral oophorectomy (both ovaries removed)	1.4	1.6	2.3	1.5	-1.0
Hair/balding pattern: Pattern 2	1.4	1.7	2.7	0.9	-1.6
Illnesses of father: High blood pressure	1.4	1.8	3.2	1.8	-0.6
Myopia	1.4	2.0	3.8	-2.0	0.3
Alcohol drinker status: Previous	1.4	1.6	1.9	-1.1	1.4
Alzheimer’s Disease (including proxy)	1.3	1.8	2.2	-1.5	1.2
Ovarian Cancer	1.3	1.8	2.3	-1.5	1.1
Schizophrenia (2014)	1.3	2.9	3.8	-1.9	1.4
Hayfever, allergic rhinitis or eczema	1.3	2.8	3.1	1.6	-1.8
High blood pressure (mother)	1.3	1.9	2.7	-1.6	1.0
Nervous feelings	1.3	2.4	4.5	0.5	-2.1
Pulse wave peak to peak time	1.3	1.6	2.5	0.8	-1.6
Medication: Ibuprofen	1.3	1.5	2.1	1.5	-0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.3	1.6	2.9	1.7	0.4
Ever had bowel cancer screening	1.3	1.5	2.1	1.0	-1.5
HbA1C	1.2	1.3	1.8	1.3	0.9
Ulcerative Colitis	1.2	1.7	2.9	0.7	-1.7
Allergy or Eczema	1.2	3.1	3.6	1.9	-1.6
Fed-up feelings	1.2	2.2	3.5	1.9	-0.9
High blood pressure	1.2	3.3	5.0	-1.3	2.2
Alcohol usually taken with meals	1.2	2.0	2.6	1.6	-1.2
Depression (self-reported)	1.2	1.4	1.8	-1.0	1.4
Headache pain in last month	1.2	2.1	4.2	-2.1	0.2
Health satisfaction	1.2	1.5	3.0	1.7	-0.3
Ever had stillbirth, spontaneous miscarriage or termination	1.2	1.3	1.5	1.0	1.2
Neuroticism (2016)	1.1	1.6	2.9	-1.7	0.6
Hand grip strength (left)	1.1	2.8	5.6	-2.4	0.0
Hearing difficulty/problems: Yes	1.1	1.8	3.4	-1.8	-0.3
Frequency of unenthusiasm / disinterest in last 2 weeks	1.1	1.4	2.8	0.0	-1.7
Stomach or abdominal pain in last month	1.1	1.4	2.6	0.5	-1.6
Mouth/teeth dental problems: Loose teeth	1.1	1.4	2.7	-0.0	1.6
Emphysema/chronic bronchitis	1.1	1.2	1.9	-1.4	0.7
Medication: Aspirin	1.1	1.4	2.7	0.3	1.7
Hypertension (Self-reported)	1.1	3.1	4.9	-1.1	2.2
LDL Cholesterol	1.0	1.6	2.4	-0.8	1.6
Blood Red Count	1.0	9.3	10.5	-3.2	2.9
Lung FEV1/FVC ratio	1.0	5.1	9.7	3.1	-0.7
Current tobacco smoking	1.0	1.6	2.2	1.5	-1.0
Heel bone mineral density (BMD) T-score, automated (right)	1.0	2.2	4.1	0.5	-2.0
Illnesses of siblings	1.0	1.4	2.7	-1.6	-0.2
Neuroticism score	1.0	2.2	3.7	0.8	-1.9
Alcohol intake versus 10 years previously	1.0	1.5	2.6	-0.7	1.6
Miserableness	1.0	1.8	3.6	-0.0	-1.9
Heart disease (siblings)	1.0	1.3	2.3	0.4	1.5
Bipolar Disorder (2018)	0.9	1.5	2.8	-0.3	1.7
Depressed Affect (Nagel 2018)	0.9	1.9	2.9	1.7	-0.9
Breast Cancer	0.9	2.1	3.3	1.8	-0.9
Body Mass Index (BMI) (2010)	0.9	1.3	1.4	-1.1	1.2
Lung cancer (father)	0.9	1.0	1.9	-0.3	1.4
Shortness of breath walking on level ground	0.9	1.0	1.5	1.2	-0.7
Qualifications: College or University degree	0.9	2.8	4.9	-2.2	0.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.9	1.1	1.5	0.9	-1.2
Smoking status: Current	0.9	1.4	1.9	1.4	-0.9
Medication: Bendroflumethiazide	0.9	1.3	1.5	-1.2	1.1
Vascular/heart problems diagnosed by doctor	0.9	2.4	4.0	0.9	-2.0
Worry (Nagel 2018)	0.8	1.7	2.6	0.9	-1.6
Triglycerides	0.8	1.4	1.7	1.3	-1.0
Type 2 Diabetes (T2D) (2012)	0.8	0.9	1.9	-1.4	0.0
Blood White Count	0.8	5.8	6.9	-2.2	2.6
Neuroticism	0.8	1.8	2.7	1.0	-1.7
Sensitivity / hurt feelings	0.8	1.3	2.2	0.7	-1.5
Hayfever/allergic rhinitis (self-reported)	0.8	1.0	1.5	-1.2	0.7
Frequency of tiredness / lethargy in last 2 weeks	0.8	1.3	1.9	0.9	-1.4
Falls in the last year	0.8	1.1	1.5	-0.8	1.2
Hair/balding pattern: Pattern 3	0.8	1.2	2.1	0.4	1.5
Peak expiratory flow (PEF)	0.8	1.9	3.7	1.9	0.0
Comparative body size at age 10	0.8	2.3	4.1	2.0	-0.6
Pulse rate, automated reading	0.8	2.5	3.4	-1.3	1.8
Alcohol intake frequency.	0.8	1.9	2.1	-1.3	1.5
Illnesses of siblings: Diabetes	0.8	0.9	1.7	0.4	1.3
Commuting to job workplace: Walk	0.8	0.8	1.6	-0.1	-1.3
Number of self-reported non-cancer illnesses	0.8	1.4	2.9	-0.2	1.7
Financial situation satisfaction	0.8	0.9	1.1	0.9	-1.0
Verbal and Numeric Reasoning (VNR)	0.7	1.7	3.1	0.6	-1.7
Number of treatments/medications taken	0.7	1.3	2.6	1.6	0.1
Severe depression (siblings)	0.7	0.8	1.4	-1.2	0.4
Had menopause	0.7	0.8	1.1	0.8	1.0
Allergy	0.7	1.5	1.8	-1.1	1.3
Fluid intelligence score	0.7	1.5	2.7	-0.5	-1.6
Noisy workplace	0.7	0.8	1.0	-1.0	0.9
Mouth/teeth dental problems: Dentures	0.7	1.2	1.4	-1.0	1.2
Neck or shoulder pain in last month	0.7	1.0	1.9	1.4	-0.3
Migraine (self-reported)	0.7	0.9	1.4	-1.2	0.7
Heart disease (mother)	0.7	0.8	1.6	0.2	1.2
Illness, injury, bereavement, stress in last 2 years	0.7	0.8	1.6	1.2	-0.4
Illnesses of father: Heart disease	0.7	1.0	1.4	-0.8	-1.2
Smoking status: Previous	0.7	1.0	2.0	-0.0	1.4
Osteoarthritis (self-reported)	0.7	1.0	1.1	0.9	1.0
Average weekly champagne plus white wine intake	0.7	0.9	1.8	0.3	-1.3
Mother’s age at death	0.7	0.9	1.8	1.3	-0.0
High cholesterol (Self-reported)	0.7	1.3	1.4	1.2	1.1
Medication: Lisinopril	0.7	0.9	1.7	0.1	1.3
Lupus	0.6	0.9	1.1	-0.9	1.1
Primary Biliary Cirrhosis	0.6	0.9	1.8	-1.3	0.0
Height	0.6	11.9	19.0	-2.2	4.4
Ever used hormone-replacement therapy (HRT)	0.6	0.7	0.9	0.9	0.7
Angina	0.6	0.8	1.2	-1.1	0.6
Leg fat-free mass (left)	0.6	3.1	3.5	-1.9	1.6
Hand grip strength (right)	0.6	1.5	2.3	-0.9	-1.5
Chronic bronchitis/emphysema (father)	0.6	0.7	0.9	-0.9	0.8
Leg predicted mass (left)	0.6	3.3	3.7	-1.9	1.7
Past tobacco smoking	0.6	1.1	2.1	-0.5	-1.4
Medication: Simvastatin	0.6	0.8	1.4	1.2	0.5
Happiness	0.6	0.7	0.9	0.7	-1.0
Asthma	0.6	1.2	1.7	0.8	-1.3
Blood clot in the leg (DVT)	0.6	0.7	1.4	1.2	-0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.6	0.7	0.7	-0.8	0.8
Mood swings	0.6	1.1	1.3	1.1	-1.0
Leg predicted mass (right)	0.6	3.1	3.3	-1.8	1.7
Guilty feelings	0.6	0.9	1.4	0.6	-1.2
Number of operations (self-reported)	0.6	0.9	1.8	0.3	-1.3
Ever depressed for a whole week	0.6	0.8	1.5	-1.2	-0.2
Unable to work because of sickness or disability	0.6	0.8	1.5	0.3	-1.2
Pain experienced in last month	0.6	1.0	1.9	-1.4	0.4
Deep venous thrombosis (DVT) (self-reported)	0.6	0.7	1.3	1.2	0.3
Intelligence (Savage-Jansen 2018)	0.5	1.6	3.2	-1.8	0.2
Bipolar Disorder (2011)	0.5	0.5	0.8	0.9	-0.4
Ever had hysterectomy (womb removed)	0.5	0.6	0.7	0.8	-0.7
Diabetes (father)	0.5	0.6	1.2	-0.1	1.1
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.8	1.5	-0.3	-1.2
Qualifications: A levels/AS levels or equivalent	0.5	1.1	1.9	-1.4	-0.6
Length of working week for main job	0.5	0.6	1.1	1.0	0.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.6	1.0	-0.5	-1.0
Age at first live birth	0.5	0.9	1.5	-0.6	-1.2
Eye problems/disorders: None of the above	0.5	0.6	1.0	-1.0	0.4
Age at last live birth	0.5	0.8	1.4	-1.2	0.4
Whole body fat-free mass	0.5	2.7	3.4	-1.4	1.9
Leg fat-free mass (right)	0.5	2.9	3.0	-1.7	1.7
Handedness (chirality/laterality): Left-handed	0.5	0.6	0.7	-0.8	0.8
Asthma (self-reported)	0.5	1.0	1.5	0.6	-1.2
Basal metabolic rate	0.5	2.7	3.4	-1.4	1.8
Average weekly beer plus cider intake	0.5	0.8	1.5	-1.2	0.0
Age started oral contraceptive pill	0.5	0.6	1.2	-1.1	-0.2
Depression (Nagel 2018)	0.4	0.6	1.1	0.4	-1.0
Neuroticism (Nagel 2018)	0.4	0.8	1.5	1.2	-0.3
Schizophrenia vs Biploar Disorder	0.4	0.5	1.1	-1.0	-0.1
Age at First Birth	0.4	0.5	1.0	-0.1	1.0
HDL Cholesterol	0.4	0.6	1.2	-1.1	0.3
Waist Hip Ratio (WHR)	0.4	1.7	3.4	-0.1	1.8
Lung FVC	0.4	2.2	3.4	1.8	-1.0
Average weekly spirits intake	0.4	0.5	0.7	0.9	-0.6
Medication for hormone replacement therapy	0.4	0.5	0.9	-0.1	1.0
Diabetes (mother)	0.4	0.5	0.9	-0.3	0.9
Taking other prescription medications	0.4	0.6	1.2	1.1	-0.1
Heel bone mineral density (BMD) T-score, automated (left)	0.4	1.0	1.9	0.2	-1.4
Medication: Atenolol	0.4	0.5	1.0	-1.0	-0.2
Impedance of leg (left)	0.4	1.8	3.4	1.8	-0.5
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	0.9	-1.0	-0.0
Pain all over the body in last month	0.4	0.4	0.8	-0.2	0.9
Trunk fat-free mass	0.4	2.3	3.3	-1.1	1.8
Time employed in main current job	0.4	0.5	0.8	0.9	-0.5
Number of live births	0.4	0.5	0.9	-0.9	0.3
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.5	0.8	0.9	0.5
Medication: Cholesterol lowering	0.4	0.7	1.3	1.1	-0.2
Trunk predicted mass	0.4	2.5	3.5	-1.3	1.9
Pulse wave reflection index	0.4	0.6	1.1	-0.1	1.0
Birth weight	0.4	0.8	1.0	1.0	0.7
Angina (self-reported)	0.4	0.5	0.8	-0.9	0.6
Knee pain experienced in last month	0.4	0.6	1.2	0.0	1.1
Long-standing illness, disability or infirmity	0.4	0.7	1.3	1.1	-0.0
Mouth/teeth dental problems: Mouth ulcers	0.4	0.7	1.2	-1.1	0.4
Osteoporosis (self-reported)	0.4	0.5	0.9	-0.4	0.9
Whole body water mass	0.4	2.5	3.0	-1.4	1.7
Wears glasses or contact lenses	0.4	0.4	0.8	0.3	0.9
BMI	0.3	1.5	2.0	-1.4	1.0
Smoking Status	0.3	0.6	1.1	1.1	0.2
Tanning	0.3	3.1	6.0	-0.3	2.5
Sitting height	0.3	1.9	3.7	-0.3	1.9
Qualifications: None of the above	0.3	0.7	1.0	1.0	0.7
Weight	0.3	1.3	1.7	-0.9	1.3
Standing height	0.3	2.9	5.3	-0.7	2.3
Loud music exposure frequency	0.3	0.3	0.6	-0.0	-0.8
Medication: Paracetamol	0.3	0.4	0.7	-0.9	0.4
Worry too long after embarrassment	0.3	0.5	0.8	0.5	-0.9
Wheeze or whistling in the chest in last year	0.3	0.5	1.0	-0.3	-1.0
Medication for pain relief, constipation, heartburn	0.3	0.5	0.9	-1.0	0.2
Medication: Blood pressure	0.3	0.5	0.6	-0.8	0.5
Medication: Allopurinol	0.3	0.3	0.5	-0.7	-0.4
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.6	1.1	0.0	1.1
Qualifications: nursing, teaching	0.3	0.4	0.6	-0.8	-0.5
Breast cancer (self-reported)	0.3	0.3	0.5	0.2	-0.7
Ever taken oral contraceptive pill	0.3	0.3	0.5	-0.7	0.4
Ever smoked	0.3	0.5	0.9	1.0	0.4
Arm fat-free mass (left)	0.3	1.4	2.5	-0.6	1.6
Arm predicted mass (left)	0.3	1.3	2.2	-0.7	1.5
Alzheimer’s Disease (in mother)	0.2	0.2	0.3	-0.2	-0.6
Mean Putamen Volume	0.2	0.3	0.5	-0.7	-0.2
Blood Eosinophil Count	0.2	1.6	3.2	1.8	0.1
Blood Platelet Count	0.2	2.6	4.3	-1.0	-2.1
Chronotype (morning person)	0.2	0.6	0.8	0.9	0.6
Relative age of first facial hair	0.2	0.5	0.8	0.9	-0.4
Vitamin and mineral supplements	0.2	0.3	0.5	-0.2	-0.7
Impedance of leg (right)	0.2	1.1	2.0	1.4	-0.4
Multivitamins +/- minerals	0.2	0.2	0.4	-0.1	0.6
Supplements: Glucosamine	0.2	0.3	0.4	0.6	-0.4
Waist circumference	0.2	0.8	1.2	-0.6	1.1
Hearing difficulty/problems with background noise	0.2	0.4	0.7	-0.9	-0.1
Diabetes (self-reported)	0.2	0.3	0.4	0.4	0.7
Arm fat percentage (right)	0.2	0.7	1.2	-1.1	0.4
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	0.6	0.0	-0.8
Mouth/teeth dental problems: Bleeding gums	0.2	0.3	0.5	-0.7	0.1
High blood pressure (siblings)	0.2	0.2	0.4	0.6	0.3
Suffer from ‘nerves’	0.2	0.2	0.4	-0.3	-0.6
Family relationship satisfaction	0.2	0.2	0.3	-0.6	0.3
Leg pain on walking	0.2	0.3	0.5	-0.1	-0.7
Supplements: Vitamin C	0.2	0.2	0.4	-0.2	0.6
Diabetes diagnosed by doctor	0.2	0.3	0.5	-0.1	0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.4	0.6	0.4	-0.8
Hearing aid user	0.2	0.3	0.3	0.6	-0.5
Commuting to job workplace: Public transport	0.2	0.2	0.4	-0.2	0.6
Medication: Atorvastatin	0.2	0.3	0.6	-0.0	0.8
Irritability	0.2	0.3	0.6	0.2	0.8
Fractured/broken bones in last 5 years	0.2	0.3	0.3	-0.6	0.5
Commuting to job workplace: Cycle	0.2	0.3	0.5	-0.7	0.2
Heart attack/myocardial infarction (self-reported)	0.2	0.3	0.4	-0.5	0.6
Hair Pigment	0.1	4.1	5.4	2.3	-1.7
Medication: Co-codamol	0.1	0.1	0.2	-0.0	0.5
Medication: Metformin	0.1	0.2	0.3	0.2	0.6
Average weekly fortified wine intake	0.1	0.2	0.3	-0.1	-0.6
Maternal smoking around birth	0.1	0.2	0.2	0.3	0.5
Relative age voice broke	0.1	0.1	0.2	-0.4	-0.3
Qualifications: CSEs or equivalent	0.1	0.1	0.1	-0.2	0.3
Trunk fat mass	0.1	0.4	0.5	-0.6	0.7
Financial difficulties in last 2 years	0.1	0.2	0.3	0.6	0.2
Forced expiratory volume in 1-second (FEV1)	0.1	0.4	0.9	0.9	0.2
Prospective memory result	0.1	0.1	0.2	-0.3	0.4
Impedance of arm (left)	0.1	0.2	0.4	0.3	-0.6
Arm fat mass (right)	0.1	0.5	0.9	-0.9	0.5
Tense / ‘highly strung’	0.1	0.2	0.2	-0.3	-0.5
Hair/balding pattern: Pattern 4	0.1	0.3	0.7	0.0	0.8
Medication for cholesterol, blood pressure or diabetes	0.1	0.1	0.1	-0.3	-0.3
Gout (self-reported)	0.1	0.2	0.3	0.1	-0.6
Chronic bronchitis/emphysema (mother)	0.1	0.1	0.2	0.5	-0.0
Arm fat-free mass (right)	0.1	0.6	1.0	-0.4	1.0
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.1	0.1	-0.4	-0.4
Medication: Omeprazole	0.1	0.1	0.1	0.3	-0.3
Mean time to correctly identify matches	0.1	0.1	0.2	-0.4	0.4
Whole body fat mass	0.1	0.2	0.3	-0.3	0.6
Arm predicted mass (right)	0.1	0.6	1.1	-0.2	1.1
Overall health rating	0.1	0.3	0.5	0.7	0.2
Chest pain or discomfort	0.1	0.1	0.2	-0.5	-0.1
Had major operations	0.1	0.2	0.3	0.6	0.2
Qualifications: NVQ or HND or HNC or equivalent	0.1	0.1	0.2	0.2	-0.4
Commuting to job workplace: Car/motor vehicle	0.1	0.2	0.2	0.5	-0.3
Arm fat percentage (left)	0.1	0.2	0.4	-0.6	-0.0
Mineral and other dietary supplements	0.1	0.2	0.4	-0.6	0.2
Arm fat mass (left)	0.1	0.2	0.4	-0.6	0.3
Tinnitus: Yes, now most or all of the time	0.1	0.1	0.1	0.2	0.3
Supplements: Fish oil (including cod liver oil)	0.1	0.1	0.1	0.4	-0.4
Medication: Paracetamol	0.1	0.1	0.2	0.1	0.5
Alcohol drinker status: Never	0.1	0.1	0.1	0.4	0.4
Reaction Time	0.0	0.1	0.1	0.1	-0.3
Respiratory disease	0.0	0.1	0.1	-0.0	-0.4
Type 2 Diabetes (T2D) (2018)	0.0	0.1	0.1	-0.3	-0.0
Pack years adult smoking proportion	0.0	0.1	0.1	0.3	0.1
Trunk fat percentage	0.0	0.2	0.2	-0.5	0.4
Age when periods started (menarche)	0.0	0.0	0.0	0.1	0.1
Diverticular disease/diverticulitis (self-reported)	0.0	0.0	0.0	-0.2	-0.2
Body mass index (BMI)	0.0	0.2	0.4	-0.6	0.2
Number of incorrect matches in round	0.0	0.0	0.0	0.1	-0.1
Forced vital capacity (FVC)	0.0	0.0	0.0	-0.0	-0.1
Heart attack	0.0	0.1	0.1	-0.1	0.3
Impedance of arm (right)	0.0	0.0	0.1	-0.2	-0.1
Hip circumference	0.0	0.1	0.2	-0.4	-0.2
Pulse rate	0.0	0.0	0.0	-0.2	0.2
Medication: Lansoprazole	0.0	0.0	0.0	-0.1	0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.0	0.0	0.0	0.1	0.1
Breastfed as a baby	0.0	0.0	0.0	0.2	-0.1
Ever highly irritable/argumentative for 2 days	0.0	0.0	0.1	-0.1	-0.2
Forced vital capacity (FVC), Best measure	0.0	0.1	0.2	-0.5	0.2
Body fat percentage	0.0	0.1	0.1	-0.2	0.3
Leg fat percentage (right)	0.0	0.0	0.0	0.2	0.1
Medication: Seretide 50 evohaler	0.0	0.0	0.0	-0.1	-0.1
Leg fat mass (right)	0.0	0.1	0.2	-0.2	0.4
Comparative height size at age 10	0.0	0.3	0.3	0.4	0.6
Average weekly red wine intake	0.0	0.0	0.1	0.3	-0.1
Friendships satisfaction	0.0	0.0	0.0	-0.0	0.0
Medication: Gliclazide	0.0	0.0	0.1	0.2	-0.1
Illnesses of father: None of the above (group 1)	0.0	0.0	0.1	0.1	0.3
Leg fat percentage (left)	0.0	0.1	0.2	0.4	-0.0
Medication: Omeprazole (e.g. Zanprol)	0.0	0.0	0.1	0.1	-0.3
Pack years of smoking	0.0	0.1	0.1	0.4	0.1
Impedance of whole body	0.0	0.3	0.4	0.6	-0.4
Leg fat mass (left)	0.0	0.1	0.1	-0.1	0.4

Hub : Genes

DNAJC28

Models

Trait associations