TWAS hub - DNASE2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Brain Cerebellar Hemisphere	0.4550	0.1070	2.0e-04	0.099	NA	0.058	NA	0.064	1.7e-03	NA	1.4e-02	NA	9.8e-03
2	GTEx	Muscle Skeletal	0.1926	0.0390	3.3e-12	0.164	NA	0.157	NA	0.153	7.0e-16	NA	3.5e-15	NA	7.4e-15
3	GTEx	Thyroid	0.0850	0.0380	9.3e-03	0.024	NA	0.005	NA	0.025	6.1e-03	NA	1.2e-01	NA	5.2e-03
4	GTEx	Whole Blood	0.0860	0.0370	3.0e-03	0.031	NA	0.028	NA	0.019	6.9e-04	NA	1.3e-03	NA	6.0e-03
5	NTR	Blood	0.0501	0.0126	5.6e-11	0.051	0.041	0.052	0.053	0.051	4.9e-16	3.0e-13	1.8e-16	1.7e-16	3.9e-16
6	YFS	Blood	0.2164	0.0305	0.0e+00	0.273	0.266	0.292	0.218	0.287	1.3e-89	4.6e-87	4.5e-97	1.6e-69	8.5e-95
7	TCGA	Breast Invasive Carcinoma	0.0279	0.0150	2.8e-03	0.015	0.006	0.014	NA	0.013	4.2e-04	1.5e-02	5.5e-04	NA	1.0e-03
8	TCGA	Kidney Renal Clear Cell Carcinoma	0.0389	0.0302	9.1e-03	0.012	0.017	0.023	NA	0.020	1.4e-02	4.0e-03	1.1e-03	NA	2.2e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Blood Red Count	17.1	165.2	282.2	-14.7	-16.5	-1.8	-15.4	-6.2	-14.5	7.9	16.8
Diabetes (self-reported)	5.9	9.1	24.2	-4.9	-3.1	-1.6	-3.0	-3.4	-3.3	-1.7	1.7
Type 2 Diabetes (T2D) (2018)	4.9	9.1	22.4	-4.7	-3.1	-1.8	-3.2	-3.2	-3.5	-1.3	1.9
Diabetes (mother)	4.9	6.3	18.9	-4.3	-2.8	-0.0	-2.7	-2.7	-2.8	-1.2	-0.1
Medication: Metformin	4.4	6.2	21.5	-4.6	-2.1	-2.4	-2.3	-2.1	-2.4	-0.3	1.7
Family relationship satisfaction	4.2	5.2	8.2	-1.5	-2.5	-2.4	-2.6	-2.5	-2.0	-1.4	2.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	3.7	4.3	11.5	1.8	3.4	0.0	2.2	2.1	3.0	0.4	-0.9
BMI	3.4	19.9	45.0	-3.0	-5.8	-0.3	-6.7	-4.1	-6.3	-0.9	3.7
Diabetes diagnosed by doctor	3.3	5.3	19.0	-4.4	-2.1	-1.9	-1.8	-2.3	-2.2	-1.2	1.1
Hair/balding pattern: Pattern 3	3.0	4.5	7.6	-1.8	-2.6	0.6	-2.4	-2.8	-2.2	-2.3	1.4
Smoking status: Previous	3.0	4.5	10.8	3.3	2.4	-0.9	2.3	1.0	2.4	-1.5	-2.3
Leg pain on walking	2.7	3.4	6.6	1.4	2.5	-1.0	1.7	2.6	2.1	1.8	-1.0
Hip circumference	2.6	11.1	21.1	-2.2	-3.8	-1.2	-4.4	-3.9	-4.6	-3.3	1.4
Loneliness, isolation	2.6	3.5	6.3	-2.3	-1.5	-1.6	-1.6	-1.7	-1.9	-1.7	2.5
Alcohol drinker status: Never	2.5	3.0	6.5	1.7	2.0	-1.0	2.5	1.6	2.5	-0.1	-0.9
Handedness (chirality/laterality): Left-handed	2.4	2.9	6.9	-0.5	1.8	-0.5	2.0	2.3	2.6	1.7	-0.8
Mouth/teeth dental problems: Mouth ulcers	2.4	3.8	7.7	0.2	1.9	-2.8	2.3	2.0	2.1	1.3	-2.1
Wears glasses or contact lenses	2.4	2.8	7.2	-0.6	-1.6	-1.6	-2.7	-2.1	-1.8	-1.4	-0.1
Falls in the last year	2.3	3.2	6.7	1.1	-1.8	-0.8	-2.0	-1.8	-2.6	-1.6	1.9
Qualifications: O levels/GCSEs or equivalent	2.2	3.5	8.3	-0.7	-2.6	-0.9	-2.9	-2.2	-2.2	-1.2	-0.1
Number of full brothers	2.1	2.6	4.9	-1.3	-1.4	1.0	-2.2	-1.9	-2.2	-0.8	1.3
Breast cancer (self-reported)	2.1	2.5	4.7	1.7	1.5	0.8	2.2	1.8	1.9	0.6	-1.3
Risk taking	2.1	3.1	6.9	-0.4	-2.1	-1.0	-2.6	-2.1	-1.9	-1.7	1.0
Primary Biliary Cirrhosis	2.0	2.9	5.4	-2.1	-1.2	1.0	-1.8	-2.3	-1.4	-2.3	-0.5
Basal cell carcinoma (self-reported)	2.0	2.4	4.7	1.8	1.8	0.9	1.5	1.8	2.2	1.3	-0.2
Breast Cancer	1.9	4.5	25.1	-5.0	-1.6	1.4	-1.0	-1.2	-1.7	0.9	-0.5
Diabetes (father)	1.9	2.3	6.5	-2.5	-1.2	1.9	-0.3	-1.4	-1.1	-1.6	1.0
Hair/balding pattern: Pattern 2	1.9	2.4	8.1	1.0	1.2	-2.8	0.9	1.8	1.0	1.8	0.7
Impedance of arm (left)	1.9	8.8	14.2	3.3	3.6	-1.6	3.8	2.6	3.5	0.6	-3.2
Illnesses of father: Heart disease	1.9	2.6	5.3	-0.8	-2.0	0.8	-2.3	-1.4	-1.7	-0.8	2.2
Average weekly champagne plus white wine intake	1.9	2.7	7.1	-0.8	-2.0	-0.6	-1.9	-0.8	-2.0	1.0	2.7
Waist Hip Ratio (WHR)	1.8	8.1	17.5	3.1	3.0	1.7	3.2	3.1	4.2	1.4	-2.0
Worrier / anxious feelings	1.8	3.5	8.0	0.3	2.8	-0.1	2.4	2.1	2.4	1.1	-1.5
Hand grip strength (left)	1.7	4.4	9.2	2.9	2.6	1.0	2.1	1.8	3.0	-0.1	-1.3
Impedance of arm (right)	1.7	8.0	12.7	3.1	3.5	-2.1	3.6	2.4	3.1	0.2	-3.2
Qualifications: A levels/AS levels or equivalent	1.7	3.8	9.1	-0.2	-3.0	-0.5	-2.7	-2.5	-2.3	-1.5	0.0
Illnesses of mother	1.7	2.1	5.2	1.8	1.9	-0.2	2.3	1.6	1.5	0.1	-0.2
Hearing aid user	1.7	1.9	5.3	-0.2	-1.6	-2.3	-1.2	-1.4	-1.6	-1.0	0.6
Allergy or Eczema	1.6	4.1	6.3	-2.1	-2.5	2.5	-2.3	-1.9	-2.5	-0.6	1.0
Osteoarthritis (self-reported)	1.6	2.1	6.0	-0.5	-2.1	0.6	-2.4	-1.2	-1.7	-0.7	1.0
Medication: Omeprazole (e.g. Zanprol)	1.6	2.0	6.1	0.4	2.5	-0.1	1.6	1.7	1.9	0.4	-0.1
Ulcerative Colitis (UC)	1.5	2.9	5.9	1.4	2.0	-0.3	2.4	2.0	2.4	1.0	-0.8
Medication: Lansoprazole	1.5	1.7	4.8	1.0	2.2	-0.4	1.8	1.2	1.5	0.1	-1.0
Financial situation satisfaction	1.5	1.9	5.2	-0.5	-1.5	-0.4	-1.8	-1.3	-1.3	-0.8	2.3
HbA1C	1.4	1.5	5.7	-0.3	-0.5	-0.4	-1.1	0.7	-0.1	2.4	2.1
Type 2 Diabetes (T2D) (2012)	1.4	1.7	8.5	-2.9	-1.1	0.1	-1.2	-0.7	-1.3	0.0	0.0
Past tobacco smoking	1.4	2.6	10.5	-3.2	-1.2	1.9	-1.2	-0.5	-1.2	1.1	0.9
Nervous feelings	1.4	2.7	4.6	2.1	1.7	-0.4	2.1	1.9	2.1	1.1	-0.3
Hearing difficulty/problems with background noise	1.4	2.2	6.1	-1.0	-1.1	-1.4	-1.4	-1.5	-0.9	-1.5	2.5
Pulse rate	1.4	2.4	5.5	-0.2	1.5	-1.7	1.6	1.7	2.3	1.2	-1.2
Ever had stillbirth, spontaneous miscarriage or termination	1.4	1.5	5.1	1.7	0.7	-0.8	0.5	-0.4	0.2	-2.3	-1.5
Heart disease (siblings)	1.4	1.7	2.8	-1.7	-1.5	0.8	-1.5	-1.4	-1.4	0.0	1.3
Intelligence (Savage-Jansen 2018)	1.3	4.1	12.0	0.5	-3.1	-2.0	-3.5	-1.6	-1.8	-0.5	0.8
Ever had hysterectomy (womb removed)	1.3	1.5	3.2	-1.7	-1.4	-1.8	-0.9	-0.5	-1.3	0.8	0.7
Body mass index (BMI)	1.3	5.5	12.4	-1.8	-3.0	-0.7	-3.5	-2.0	-3.1	-0.6	2.2
Happiness	1.3	1.6	6.3	0.1	-0.7	-2.5	-1.3	-1.1	-1.0	-1.4	0.2
High blood pressure (siblings)	1.3	1.9	3.0	-1.3	-1.6	-0.0	-1.7	-1.7	-1.6	-1.7	0.0
Age at last live birth	1.3	1.8	3.9	1.1	2.0	0.7	1.6	1.0	1.4	0.2	-1.9
Medication: Lisinopril	1.3	1.7	3.3	0.0	1.2	0.5	1.8	1.7	1.7	0.9	-1.4
Blood Eosinophil Count	1.2	9.1	20.6	-2.5	-4.5	-1.9	-4.0	-2.9	-3.4	-0.6	2.4
Heel bone mineral density (BMD) T-score, automated (left)	1.2	2.6	10.4	-0.8	-1.8	0.9	-1.7	-1.4	-1.0	-0.1	3.2
Financial difficulties in last 2 years	1.2	1.7	3.5	0.2	-1.7	-1.6	-1.9	-0.3	-1.0	0.5	1.8
Exposure to tobacco smoke outside home	1.2	1.6	7.0	-2.6	-0.8	-0.7	-1.4	-0.5	-1.1	0.5	1.1
Medication: Omeprazole	1.2	1.4	5.2	0.5	2.3	-0.4	1.2	1.0	1.5	-0.8	-0.0
Qualifications: NVQ or HND or HNC or equivalent	1.2	1.5	4.2	0.3	1.0	2.1	1.4	1.1	0.6	1.2	1.3
Eye problems/disorders: Cataract	1.2	1.4	4.9	-1.8	-1.1	0.6	-0.5	-0.7	-0.4	0.3	2.2
Leg fat percentage (left)	1.2	4.3	7.0	-2.0	-2.6	-0.3	-2.6	-2.1	-2.4	-1.6	1.8
Myopia	1.2	1.8	3.2	-1.5	-1.0	0.2	-1.7	-1.8	-1.2	-1.8	-0.3
Alcohol drinker status: Previous	1.2	1.3	9.0	3.0	1.0	-0.5	-0.2	0.4	0.3	0.1	0.3
Ovarian Cancer	1.1	1.5	3.1	-0.7	-1.4	0.5	-1.6	-1.8	-1.5	-1.1	-0.3
Prostate Cancer	1.1	1.5	3.8	1.4	1.3	0.4	1.4	1.5	1.9	0.6	-0.6
Cardiovascular Disease	1.1	3.6	5.4	-2.3	-2.1	1.0	-1.9	-2.3	-1.9	-2.3	0.6
Illnesses of siblings	1.1	1.5	2.3	1.5	1.4	-0.1	1.5	1.5	1.4	0.9	-0.7
Noisy workplace	1.1	1.3	2.8	0.6	1.5	-0.9	1.4	1.7	1.3	0.9	0.2
Medication: Ibuprofen (e.g. Nurofen)	1.1	1.4	4.1	0.2	-1.0	0.2	-1.8	-0.9	-1.4	-0.0	2.0
Peak expiratory flow (PEF)	1.1	2.5	13.9	3.7	0.7	0.9	1.2	0.5	1.5	-0.9	0.1
Loud music exposure frequency	1.1	1.2	3.0	0.7	1.7	0.3	1.7	0.9	1.4	-0.3	-0.5
Leg fat percentage (right)	1.1	4.0	6.5	-1.6	-2.5	-0.2	-2.4	-2.2	-2.4	-1.8	1.8
Seen a psychiatrist for nerves, anxiety, tension or depression	1.1	1.5	5.9	2.0	-0.4	-2.4	-0.6	0.7	-0.1	0.8	0.2
Medication: Allopurinol	1.1	1.4	2.5	-0.7	-1.5	-0.5	-1.3	-1.6	-1.6	-1.3	-0.4
Chest pain or discomfort	1.1	1.6	3.2	-0.0	-1.8	-0.1	-1.1	-1.8	-1.5	-1.4	0.8
Friendships satisfaction	1.1	1.3	2.6	-1.1	-1.2	-0.0	-1.6	-1.1	-1.4	-0.5	1.4
Medication: Aspirin	1.1	1.5	4.0	0.1	-0.8	-2.0	-1.4	-1.6	-0.9	-1.3	0.5
Impedance of whole body	1.1	5.8	12.5	2.1	3.0	-0.9	3.5	1.6	2.9	-0.5	-2.8
Schizophrenia (2014)	1.0	2.3	11.9	1.3	-0.3	-0.2	0.0	-2.1	-0.5	-3.5	0.0
Blood Platelet Count	1.0	11.3	29.6	0.9	3.4	-1.2	3.1	-0.7	2.9	-5.4	-5.3
Pack years adult smoking proportion	1.0	1.5	6.8	-0.3	0.9	2.6	1.5	0.8	0.7	0.7	0.1
High blood pressure (mother)	1.0	1.5	3.3	-1.0	-1.8	-0.7	-1.8	-1.4	-1.3	-0.4	0.2
Forced vital capacity (FVC)	1.0	4.0	12.4	3.5	1.8	1.6	2.0	1.8	2.0	0.9	-1.2
Forced expiratory volume in 1-second (FEV1)	1.0	3.5	17.4	4.2	1.2	1.6	1.3	1.3	1.7	0.3	-0.4
Prospective memory result	1.0	1.3	2.5	-0.9	1.3	-1.5	1.6	0.7	0.8	0.3	-1.3
Leg fat mass (right)	1.0	4.0	8.7	-0.8	-2.7	-0.7	-2.9	-2.0	-2.7	-1.3	1.5
Arm fat mass (left)	1.0	4.0	10.4	-0.7	-2.5	-1.2	-3.2	-1.6	-2.9	-0.4	1.7
Medication: Paracetamol	1.0	1.5	4.6	-2.1	1.2	1.8	0.3	-0.7	0.3	-1.3	0.3
Age started oral contraceptive pill	1.0	1.2	5.5	-1.7	0.4	-2.3	0.4	0.3	0.3	0.3	-0.8
Ever depressed for a whole week	1.0	1.2	3.2	-0.3	0.6	-1.8	0.4	1.6	0.9	1.5	0.0
Leg fat mass (left)	1.0	4.0	9.1	-1.0	-2.6	-0.8	-3.0	-1.9	-2.7	-1.1	1.5
Irritable Bowel Disease (IBD)	0.9	2.2	5.2	1.6	1.8	0.3	2.2	1.2	2.3	-0.2	-0.7
Triglycerides	0.9	1.4	3.9	-0.0	1.6	-0.4	1.1	1.5	2.0	0.8	-0.8
Chronotype (morning person)	0.9	2.0	4.7	1.2	1.6	2.2	1.4	1.2	1.5	0.4	-1.3
Hearing difficulty/problems: Yes	0.9	1.4	3.3	-1.0	-1.2	-1.8	-1.6	-0.9	-0.9	-0.7	0.9
Eye problems/disorders: Diabetes related eye disease	0.9	1.0	3.7	-1.3	0.5	-1.9	0.7	0.6	0.3	0.4	1.2
Townsend deprivation index at recruitment	0.9	1.3	5.1	0.6	0.7	-1.1	0.2	1.0	0.6	1.5	2.2
Age when periods started (menarche)	0.9	2.3	6.8	2.6	1.4	0.8	1.9	0.4	0.8	-0.8	-2.0
Mouth/teeth dental problems	0.9	1.3	5.2	1.0	-1.3	0.9	-2.3	-0.8	-1.1	-0.1	0.3
Medication: Cholesterol lowering	0.9	1.4	3.1	1.2	0.9	-0.4	0.5	1.7	1.6	1.8	0.2
Arm fat mass (right)	0.9	3.8	9.5	-0.6	-2.4	-1.2	-3.1	-1.6	-2.8	-0.7	1.5
Neck or shoulder pain in last month	0.9	1.3	3.6	-1.9	1.1	-1.6	1.2	-0.1	0.6	-0.4	1.0
Qualifications: nursing, teaching	0.9	1.5	5.7	0.4	-1.6	0.0	-2.4	-0.9	-1.6	0.3	0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.9	2.0	5.3	1.7	1.4	-0.5	0.7	1.8	2.3	1.3	-0.5
Pack years of smoking	0.9	1.3	5.8	-0.3	1.0	2.4	1.6	0.7	0.8	0.3	0.0
Arm predicted mass (left)	0.9	4.6	10.6	-0.7	-2.6	0.4	-3.2	-2.3	-3.1	-1.3	1.3
Schizophrenia vs Biploar Disorder	0.8	1.0	2.7	-1.5	-0.7	0.6	-0.5	-1.6	-1.4	0.0	0.0
Alzheimer’s Disease (in father)	0.8	0.8	2.2	1.5	0.2	-1.0	0.1	0.6	1.0	-0.9	-1.1
Verbal and Numeric Reasoning (VNR)	0.8	2.0	5.4	-0.2	-2.3	-1.7	-2.3	-0.7	-1.1	0.5	-0.6
Mean Putamen Volume	0.8	0.9	2.0	1.4	0.9	-0.7	0.8	1.1	0.8	1.0	0.1
Fasting Glucose	0.8	1.0	2.4	1.6	0.8	-0.3	0.4	1.3	1.5	0.4	-0.6
LDL Cholesterol	0.8	1.2	2.2	1.0	-0.5	0.0	-1.3	-1.4	-0.4	-1.4	1.5
Impedance of leg (right)	0.8	4.1	8.8	1.9	2.1	0.8	3.0	0.6	2.3	-1.7	-2.5
Average weekly fortified wine intake	0.8	0.9	2.3	-0.7	1.1	0.8	1.5	0.9	1.1	0.4	-0.8
Relative age voice broke	0.8	1.2	9.0	3.0	0.1	0.2	0.1	0.1	0.1	-0.3	-0.4
Impedance of leg (left)	0.8	3.9	8.9	1.5	2.2	0.5	3.0	0.9	2.5	-1.1	-2.6
Waist circumference	0.8	2.9	5.5	-0.4	-2.1	-0.4	-2.3	-2.0	-2.1	-2.0	0.9
Qualifications: None of the above	0.8	1.7	3.9	0.1	1.8	1.0	2.0	1.0	1.5	0.6	1.2
Mouth/teeth dental problems: Dentures	0.8	1.3	6.9	-2.6	0.8	-0.2	1.4	-0.2	-0.0	-1.0	0.0
Tense / ‘highly strung’	0.8	1.3	4.3	-0.9	-1.3	-0.1	-0.5	-1.4	-1.0	-0.6	2.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.2	5.9	2.4	-0.9	-0.1	-1.0	0.3	-0.4	0.1	1.4
Hair/balding pattern: Pattern 4	0.8	2.0	4.3	-1.1	-1.7	1.0	-1.3	-1.5	-2.1	-0.4	1.5
Pulse wave reflection index	0.8	1.0	6.2	-0.1	-0.4	2.5	-0.1	-0.6	-0.7	-1.0	0.1
Chronic bronchitis/emphysema (mother)	0.8	0.9	1.7	-0.5	-1.2	-1.3	-1.0	-1.0	-1.1	0.0	0.9
Qualifications: College or University degree	0.8	2.5	5.9	-1.6	-2.0	-1.1	-2.4	-1.4	-1.6	-0.9	-0.8
Number of full sisters	0.8	0.9	3.2	0.0	-1.2	-0.7	-0.9	-1.1	-1.8	-0.3	0.4
Medication: Aspirin	0.8	1.0	3.6	0.6	-0.4	-1.9	-0.9	-1.1	-0.4	-1.1	0.4
Knee pain experienced in last month	0.8	1.3	2.2	1.2	1.0	1.0	0.8	1.4	1.1	0.6	-1.5
Commuting to job workplace: Walk	0.8	0.9	2.4	-0.1	0.9	-1.2	0.5	1.2	0.8	1.6	0.5
Medication for cholesterol	0.8	1.2	6.3	2.5	0.8	-0.7	0.7	1.0	0.6	0.3	0.3
Mineral and other dietary supplements	0.8	1.0	4.3	-2.1	-0.7	1.2	-0.0	-1.1	-0.5	-0.5	0.5
Medication: Gliclazide	0.8	0.9	3.6	-1.9	0.0	-1.5	0.2	0.4	0.0	0.7	-0.6
Ever smoked	0.8	1.5	6.9	2.6	0.4	-1.9	0.3	0.1	0.4	-0.7	0.8
Arm fat-free mass (left)	0.8	3.9	9.3	-0.4	-2.4	0.5	-3.1	-2.1	-2.9	-1.1	1.4
Average weekly beer plus cider intake	0.8	1.1	5.2	2.3	-0.4	-0.5	-0.4	0.8	-0.1	1.3	0.9
Fractured/broken bones in last 5 years	0.8	1.0	4.3	-2.1	0.6	-0.9	0.5	0.6	0.4	0.9	-0.9
Alzheimer’s Disease (in mother)	0.7	0.8	2.6	0.2	-1.6	-0.2	-1.4	-1.0	-1.0	-0.5	0.4
Neuroticism (2016)	0.7	1.0	2.6	-1.3	1.0	0.8	0.7	0.7	0.8	0.6	1.6
Rheumatoid Arthritis	0.7	1.0	2.0	-1.0	-0.6	1.4	-0.7	-1.4	-0.6	-1.2	-0.8
Respiratory disease	0.7	1.6	4.0	-2.0	-0.7	-0.0	-0.9	-2.0	-1.4	-1.2	-0.4
Hayfever, allergic rhinitis or eczema	0.7	1.4	3.0	-1.5	-1.5	1.7	-1.3	-0.7	-1.3	0.3	0.1
Stomach or abdominal pain in last month	0.7	0.8	2.1	-1.2	0.3	-1.4	0.4	0.1	0.2	0.7	1.4
Number of incorrect matches in round	0.7	1.2	6.0	-2.4	0.7	-1.2	0.5	0.0	0.4	0.6	0.9
Ever unenthusiastic/disinterested for a whole week	0.7	0.8	4.4	-0.1	-0.5	-2.1	-1.1	0.1	-0.3	0.1	0.8
Hayfever/allergic rhinitis (self-reported)	0.7	0.9	3.2	-1.6	0.5	0.9	0.6	0.2	0.5	-0.3	-1.8
Weight	0.7	3.6	9.5	-0.3	-2.2	-1.0	-3.1	-1.9	-2.6	-1.2	0.9
Arm fat percentage (right)	0.7	2.8	6.9	-0.6	-2.0	-1.5	-2.6	-1.1	-2.3	-0.2	1.4
Alcohol intake versus 10 years previously	0.7	1.0	1.8	0.5	1.1	-0.7	0.9	1.4	0.6	1.3	1.2
Exposure to tobacco smoke at home	0.7	0.7	3.5	-1.9	-0.4	0.7	-0.6	-0.3	-0.6	0.2	1.0
Mouth/teeth dental problems: Bleeding gums	0.7	0.9	3.1	1.0	1.0	-0.4	1.8	0.6	1.2	0.1	-0.3
Medication: Paracetamol	0.7	1.2	4.5	-2.1	0.9	1.6	-0.1	-0.3	0.1	-0.5	1.0
Arm fat-free mass (right)	0.7	3.8	9.2	-0.6	-2.5	0.5	-3.0	-2.1	-2.7	-1.1	1.2
Eye problems/disorders: None of the above	0.7	0.9	3.4	0.9	-0.1	-0.1	-0.4	-0.7	-0.8	-1.2	-1.9
Emphysema/chronic bronchitis	0.7	0.8	2.9	-0.5	0.1	1.0	0.8	-1.3	-0.0	-1.7	-0.1
Mean time to correctly identify matches	0.7	1.3	3.1	-0.9	1.8	-1.7	1.3	0.4	1.1	-0.6	0.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.8	1.8	1.3	-0.7	1.1	0.5	-0.9	-0.9	-0.8	-0.8
Arm predicted mass (right)	0.7	3.5	8.5	-0.4	-2.4	0.6	-2.9	-2.0	-2.6	-1.0	1.1
Arm fat percentage (left)	0.7	2.7	6.7	-0.7	-2.1	-1.3	-2.6	-1.1	-2.2	-0.1	1.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.7	0.9	3.1	0.6	0.8	0.2	1.8	0.9	0.5	0.0	-1.2
Pain type(s) experienced in last month: Hip pain	0.7	0.9	4.0	-1.5	-0.5	2.0	-0.2	-0.3	-0.5	0.1	0.2
Irritability	0.7	1.2	3.5	-1.9	-0.3	-1.7	-0.6	-0.9	-0.4	-0.9	1.0
Cholesterol lowering medication	0.7	1.1	3.4	-1.8	-0.7	1.5	-0.6	-0.5	-0.8	-0.6	0.8
Ulcerative Colitis	0.6	0.9	2.0	-0.2	0.7	-1.2	0.9	1.0	1.4	1.0	0.3
Height	0.6	12.4	33.1	5.1	3.8	-0.7	3.0	1.5	2.9	-2.4	-5.8
Lung FVC	0.6	2.9	16.7	1.0	0.6	4.1	1.2	1.1	1.4	0.8	0.1
Average weekly spirits intake	0.6	0.8	1.3	-1.1	1.0	1.1	0.9	0.1	0.7	-0.7	-1.1
Medication for hormone replacement therapy	0.6	0.6	3.8	-0.8	0.6	0.2	0.1	0.2	0.3	0.5	-1.9
Supplements: Zinc	0.6	0.7	2.2	1.5	0.8	-1.2	0.0	0.4	0.9	-0.5	-0.0
Bilateral oophorectomy (both ovaries removed)	0.6	0.6	2.2	-1.5	-0.6	-0.6	-0.3	-0.5	-1.2	0.6	0.2
Tinnitus: Yes, but not now, but have in the past	0.6	0.6	1.2	0.2	1.1	-0.9	1.0	0.9	0.8	0.6	0.2
Medication: Atenolol	0.6	0.7	3.5	-1.2	-0.6	1.9	-0.2	-0.4	-0.7	-0.2	-0.3
Had menopause	0.6	0.7	2.2	-1.5	-0.7	-1.0	-0.4	-1.0	-0.5	-0.6	0.3
Medication: Ramipril	0.6	0.8	2.5	-1.6	-0.7	-0.6	-0.2	-0.8	-1.1	-0.2	1.1
Medication: Simvastatin	0.6	0.8	3.1	-0.6	-0.9	-1.2	-0.7	0.3	0.0	0.7	1.8
Number of live births	0.6	0.9	4.8	2.2	0.3	1.0	0.8	0.1	0.4	-0.0	-0.6
Glaucoma (self-reported)	0.6	0.7	1.4	-0.2	1.1	0.9	0.7	0.3	0.9	-0.6	-1.2
Medication: Amlodipine	0.6	0.9	2.8	-0.4	-1.0	0.8	-0.3	-1.4	-0.6	-1.7	0.3
Body fat percentage	0.6	2.2	4.0	-0.9	-1.7	-1.3	-2.0	-1.6	-1.9	-1.3	0.8
Worry too long after embarrassment	0.6	0.9	2.6	0.1	1.3	-1.0	1.6	0.7	1.0	0.1	-0.8
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.7	2.9	1.7	-0.5	-0.5	-0.2	-0.7	-0.6	-0.7	0.9
Migraine (self-reported)	0.6	0.7	2.7	1.6	0.1	0.9	-0.4	0.3	0.1	0.3	1.3
Whole body fat mass	0.6	2.4	5.7	-0.3	-1.8	-1.2	-2.4	-1.5	-2.1	-1.1	0.8
Long-standing illness, disability or infirmity	0.6	0.9	2.3	-1.1	-0.8	-0.9	-1.5	-1.0	-1.0	-0.3	-0.6
Ever taken oral contraceptive pill	0.6	0.7	1.4	0.1	1.0	0.2	1.2	0.8	1.2	0.2	-1.1
Unable to work because of sickness or disability	0.6	0.7	3.1	0.2	0.1	-1.8	-0.5	-0.4	-0.1	-1.4	-0.5
Deep venous thrombosis (DVT) (self-reported)	0.6	0.7	2.9	-1.0	0.3	-1.7	-0.0	0.4	0.4	1.0	-0.8
Major Depression (MDD)	0.5	0.6	1.6	0.9	-0.2	-1.0	-0.3	-0.8	-0.1	-1.3	0.8
Age at First Birth	0.5	0.7	1.3	1.1	0.7	-0.6	0.9	1.0	0.9	0.3	-1.2
Body Mass Index (BMI) (2010)	0.5	0.7	1.6	0.8	-0.8	-0.4	-0.6	-0.1	-1.3	0.8	1.2
Lupus	0.5	0.8	3.3	-0.3	-0.0	0.5	0.2	-1.1	-0.4	-1.8	-1.0
Smoking Status	0.5	1.1	4.1	2.0	1.2	-0.8	1.0	0.2	1.0	-0.6	0.2
Other serious medical condition/disability diagnosed by doctor	0.5	0.6	1.4	-0.1	1.2	0.9	0.5	1.1	0.9	0.7	0.1
Angina	0.5	0.6	2.0	-0.1	-0.1	-1.4	-0.8	-0.9	-0.6	-0.6	0.9
Medication: Co-codamol	0.5	0.6	1.5	-1.2	-0.9	-0.0	-1.0	-0.3	-1.2	0.4	-0.2
Hand grip strength (right)	0.5	1.3	2.9	1.5	1.3	1.1	0.9	0.4	1.7	-1.0	-0.3
Maternal smoking around birth	0.5	0.7	1.3	-0.9	1.1	-1.1	0.9	0.6	1.0	0.2	-0.8
Taking other prescription medications	0.5	0.7	1.5	-0.5	1.2	-0.4	0.9	0.8	1.0	0.7	-0.9
Qualifications: CSEs or equivalent	0.5	0.7	2.4	1.6	-0.8	0.2	-0.6	-0.1	-1.2	0.4	0.8
Serious illness, injury or assault to yourself	0.5	0.6	1.6	-1.1	-0.3	-0.9	-1.2	0.1	-0.3	0.5	0.7
Multivitamins +/- minerals	0.5	0.7	4.4	2.1	-0.3	-0.2	-0.6	-0.2	-0.5	-0.0	0.4
Diverticular disease/diverticulitis (self-reported)	0.5	0.6	1.2	-0.8	1.0	-0.3	0.3	0.7	1.1	0.9	-0.8
Medication: Levothyroxine sodium	0.5	0.9	2.4	1.0	0.4	1.3	0.3	0.9	0.9	0.2	-1.6
Trunk fat mass	0.5	2.3	4.8	-0.3	-1.7	-1.5	-2.2	-1.6	-2.0	-1.3	0.6
Had other major operations	0.5	0.6	2.3	-0.1	0.9	-0.0	1.5	0.7	1.0	0.7	-0.1
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.1	3.2	-1.2	-0.3	1.7	-0.6	-0.8	-0.1	-0.2	1.8
Heart attack	0.5	0.6	3.1	0.2	0.2	-0.6	0.3	0.9	0.5	1.8	-0.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.6	8.9	3.0	0.2	1.3	0.3	0.9	1.0	0.5	0.1
Ever highly irritable/argumentative for 2 days	0.5	0.6	3.5	0.2	0.5	-1.9	-0.4	0.4	0.5	0.0	-0.7
Blood clot in the leg (DVT)	0.5	0.7	2.8	-1.3	0.0	-1.7	-0.2	0.2	0.1	0.8	-0.6
Headache pain in last month	0.5	0.8	2.0	-1.4	1.4	-0.1	1.0	0.1	0.8	-0.0	0.9
Gout (self-reported)	0.5	0.7	1.3	-0.5	-1.2	-0.7	-1.0	-1.0	-1.0	-0.5	0.0
Hypothyroidism/myxoedema (self-reported)	0.5	0.9	5.2	1.0	-0.6	2.3	-0.5	-0.1	-0.3	0.0	-0.4
Forced vital capacity (FVC), Best measure	0.5	1.9	6.3	2.5	0.8	1.5	0.8	1.3	1.3	0.8	-0.9
Comparative body size at age 10	0.5	1.4	4.4	0.2	-1.1	0.7	-1.5	0.2	-1.5	2.1	1.1
Medication: Seretide 50 evohaler	0.5	0.5	1.2	0.2	-0.6	-0.5	-0.9	-1.0	-1.1	-0.7	0.0
Pulse rate, automated reading	0.5	1.5	3.4	-1.8	0.4	-1.3	0.8	1.4	0.8	1.8	-0.2
Illnesses of siblings: Diabetes	0.5	0.6	1.2	-0.8	-1.1	0.8	-0.7	-1.0	-0.7	-0.4	0.1
Forced expiratory volume in 1-second (FEV1), predicted	0.5	1.1	4.4	1.7	0.4	0.4	0.6	0.4	0.7	-0.1	-2.1
Illnesses of father: None of the above (group 1)	0.5	0.6	1.7	-0.0	0.9	1.2	0.5	-0.5	-0.4	-0.3	-1.3
Whole body water mass	0.5	2.6	8.4	0.4	-1.9	0.2	-2.9	-1.4	-2.4	-0.5	0.9
Eye problems/disorders: Glaucoma	0.5	0.6	1.3	0.7	0.8	0.8	0.7	0.4	1.2	-0.4	-1.0
High cholesterol (Self-reported)	0.5	0.9	2.3	0.7	0.0	1.5	0.4	1.1	0.6	1.2	1.0
Illnesses of father: High blood pressure	0.5	0.7	2.0	0.6	0.2	-0.8	0.3	1.2	0.6	1.4	0.5
Basal metabolic rate	0.5	2.8	8.7	0.4	-2.0	-0.0	-3.0	-1.4	-2.5	-0.7	0.9
Commuting to job workplace: Cycle	0.5	0.6	2.0	-0.2	0.4	0.3	0.7	-0.7	0.1	-1.4	-1.4
Pain experienced in last month	0.5	0.8	4.6	2.2	-0.2	0.6	0.2	0.3	-0.2	0.3	-0.9
Heart attack/myocardial infarction (self-reported)	0.5	0.7	2.8	0.1	0.5	-0.8	0.5	1.0	0.7	1.7	-0.2
Bipolar Disorder or Schizophrenia	0.4	1.0	5.3	1.1	0.0	0.3	0.2	-1.2	0.2	-2.3	0.2
Schizophrenia (2018)	0.4	0.9	4.7	0.7	-0.1	0.3	-0.0	-1.3	-0.1	-2.2	0.3
Crohns Disease (2017)	0.4	0.8	2.3	0.2	0.7	1.0	1.1	-0.5	0.9	-1.5	-0.4
Crohns Disease (2012)	0.4	0.6	1.9	-1.4	0.7	-0.5	1.0	-0.0	0.8	0.2	-0.8
Heel T-Score	0.4	2.8	12.5	-0.9	1.9	-0.5	1.7	1.0	3.5	-0.0	1.2
Lung FEV1/FVC ratio	0.4	2.1	5.9	2.2	-0.8	-2.4	-1.1	-0.2	0.1	-0.8	1.9
Sensitivity / hurt feelings	0.4	0.6	1.8	-0.0	1.1	0.2	1.3	1.1	0.7	0.6	0.2
Ever used hormone-replacement therapy (HRT)	0.4	0.5	2.0	-1.4	-0.8	-0.2	-0.4	-0.1	-0.7	0.6	0.3
Systolic blood pressure, automated reading	0.4	1.2	3.0	-1.2	-0.5	-1.7	-0.5	-1.0	-0.2	-1.7	-0.7
Severe depression (siblings)	0.4	0.5	1.4	0.0	-0.6	1.2	-0.3	0.1	-0.4	1.2	0.6
Leg fat-free mass (left)	0.4	2.2	6.7	0.5	-1.7	-0.7	-2.6	-1.1	-2.3	-0.3	1.0
Trunk fat percentage	0.4	1.6	3.5	-0.6	-1.1	-1.9	-1.5	-1.3	-1.4	-1.2	0.3
Fed-up feelings	0.4	0.7	2.3	-1.1	0.2	-0.9	0.1	-0.9	-0.4	-1.5	0.6
Supplements: Glucosamine	0.4	0.5	2.5	1.2	0.3	0.4	-0.1	0.1	-0.1	-0.0	-1.6
Chronic bronchitis/emphysema (father)	0.4	0.5	2.2	-0.4	-0.1	-1.5	0.4	-0.2	0.0	-0.1	1.1
Leg predicted mass (left)	0.4	2.0	6.2	0.5	-1.6	-0.7	-2.5	-1.0	-2.2	-0.2	0.9
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.6	3.2	-0.6	0.4	-1.0	0.3	0.1	0.5	-0.1	1.8
Allergy	0.4	0.9	2.4	1.5	1.0	-0.7	1.1	0.2	1.0	-1.0	0.3
Trunk fat-free mass	0.4	2.2	7.1	0.8	-1.7	1.0	-2.7	-1.2	-2.1	-0.6	0.5
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.6	2.2	0.5	1.0	0.0	1.5	0.7	0.9	-0.6	0.3
Trunk predicted mass	0.4	2.3	7.3	0.8	-1.8	1.1	-2.7	-1.2	-2.1	-0.6	0.6
Breastfed as a baby	0.4	0.5	2.2	1.5	-0.0	0.8	-0.7	0.1	0.3	0.2	0.6
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	2.0	-1.4	-0.1	-0.2	0.2	-1.2	-0.6	-1.2	0.5
Wheeze or whistling in the chest in last year	0.4	0.7	2.7	-1.7	0.8	-0.2	0.8	0.2	0.7	0.3	-0.8
Number of children fathered	0.4	0.4	1.5	1.2	0.0	0.6	-0.5	-0.1	0.3	-1.0	-0.0
Shortness of breath walking on level ground	0.4	0.5	1.3	-0.5	-1.1	-0.5	-0.9	-0.6	-0.9	0.1	0.3
Alcohol intake frequency.	0.4	1.0	3.3	-0.3	1.1	-1.8	0.5	0.3	0.5	-0.3	1.7
Comparative height size at age 10	0.4	2.3	5.8	2.4	1.3	-1.4	0.4	1.5	1.1	1.5	-1.6
Commuting to job workplace: Car/motor vehicle	0.4	0.4	1.5	-0.4	-0.6	-0.0	-0.7	-0.8	-0.3	-1.2	-0.6
Supplements: Vitamin C	0.4	0.5	1.5	1.2	-0.2	-0.1	-0.6	0.1	-1.1	0.7	0.6
Whole body fat-free mass	0.4	2.4	7.8	0.6	-1.8	0.2	-2.8	-1.2	-2.2	-0.5	0.8
Osteoporosis (self-reported)	0.4	0.4	2.1	-0.1	-0.7	1.4	0.4	-0.6	-0.6	-0.2	0.1
Smoking status: Current	0.4	0.6	3.1	-0.5	-0.4	-0.6	-0.5	-0.3	-0.5	0.6	1.8
Guilty feelings	0.4	0.5	1.1	0.9	0.7	0.4	1.0	0.1	1.0	-0.8	-0.3
Supplements: Fish oil (including cod liver oil)	0.4	0.5	1.1	1.0	1.0	-1.0	0.1	0.2	0.2	-0.5	-0.6
Supplements: Calcium	0.4	0.4	1.1	0.2	0.8	-0.2	1.0	0.2	0.1	-0.9	-0.9
Depression (Nagel 2018)	0.3	0.5	2.4	-0.5	-0.1	-0.5	-0.1	-0.8	-0.5	-1.6	0.3
Alzheimer’s Disease (including proxy)	0.3	0.4	1.0	0.7	-0.6	-1.0	-1.0	-0.1	-0.0	-0.5	-0.2
HDL Cholesterol	0.3	0.5	1.1	0.0	0.7	1.1	0.7	-0.0	0.4	-0.8	-0.8
Hypothyroidism (self reported)	0.3	0.7	3.5	0.7	-0.3	1.9	0.2	-0.1	-0.2	-0.6	-0.8
Relative age of first facial hair	0.3	0.6	2.1	0.5	0.5	1.5	0.8	-0.3	-0.2	-0.4	-1.0
Current tobacco smoking	0.3	0.5	2.9	-0.8	-0.2	0.1	-0.1	-0.1	-0.2	0.7	1.7
High blood pressure	0.3	0.8	2.0	-0.5	-1.4	-0.2	-1.1	-1.0	-0.9	-1.1	-0.4
Sitting height	0.3	2.1	3.5	-1.0	-1.5	-0.1	-1.9	-1.8	-1.7	-1.5	-1.1
Asthma	0.3	0.6	1.9	-1.4	-0.3	-0.5	-0.9	-0.5	-0.8	0.3	-0.9
Depression (self-reported)	0.3	0.3	1.0	-0.1	-0.2	-1.0	-0.3	0.3	-0.5	0.4	0.9
Lung cancer (father)	0.3	0.3	0.6	-0.6	-0.0	-0.6	-0.8	-0.7	-0.6	-0.4	0.5
Standing height	0.3	3.2	12.9	3.6	1.3	-0.9	0.6	0.2	0.7	-1.6	-2.6
Length of working week for main job	0.3	0.4	1.1	-0.1	0.6	-0.0	0.5	1.0	0.9	0.4	0.4
Medication: Ventolin 100micrograms inhaler	0.3	0.4	2.8	-0.0	-0.3	1.7	-0.3	-0.1	-0.5	0.3	-0.5
Age at first live birth	0.3	0.5	1.5	-0.2	-0.1	0.4	-0.9	-0.8	-0.7	-0.8	-1.2
Medication for pain relief, constipation, heartburn	0.3	0.6	2.0	0.7	-1.3	-0.2	-0.1	-0.5	-0.6	0.1	-1.4
Angina (self-reported)	0.3	0.4	1.3	-0.2	-0.1	-1.2	-0.7	-0.8	-0.5	-0.6	0.7
Had major operations	0.3	0.3	0.9	-0.6	0.3	0.7	0.4	0.2	0.4	0.9	0.7
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	1.0	0.3	0.8	1.0	0.9	0.1	0.7	-0.5	-0.1
Hypertension (Self-reported)	0.3	0.9	1.7	-0.7	-1.3	-0.3	-1.0	-1.1	-0.9	-1.2	-0.5
Leg fat-free mass (right)	0.3	1.9	6.3	0.4	-1.5	-0.9	-2.5	-0.8	-2.0	0.1	0.9
Average weekly red wine intake	0.3	0.5	1.9	0.6	-1.4	0.4	-1.1	-0.1	-0.2	0.3	0.2
Ever had bowel cancer screening	0.3	0.3	0.8	-0.5	-0.4	-0.2	-0.9	0.0	-0.3	0.8	0.6
Asthma (self-reported)	0.3	0.6	2.2	-1.5	-0.3	-0.2	-0.9	-0.5	-0.8	0.1	-0.9
Leg predicted mass (right)	0.3	1.8	6.1	0.5	-1.5	-0.8	-2.5	-0.7	-1.9	0.1	0.9
Medication: Blood pressure	0.3	0.5	2.3	-1.5	-0.8	-0.6	-0.4	-0.5	-0.3	0.2	0.4
Medication: Bendroflumethiazide	0.3	0.5	0.9	-0.4	-0.9	0.5	-1.0	-0.5	-0.8	-0.1	-0.9
Medication: Atorvastatin	0.3	0.3	0.9	-0.3	1.0	0.2	0.7	0.7	0.6	0.0	0.3
Vascular/heart problems diagnosed by doctor	0.3	0.9	1.5	0.8	1.2	1.0	1.0	1.1	0.9	1.0	0.5
Bipolar Disorder (2018)	0.2	0.3	1.0	0.8	0.2	0.2	0.3	-0.4	0.3	-1.0	-0.0
Neuroticism (Nagel 2018)	0.2	0.4	1.0	-0.9	0.6	-0.5	1.0	0.5	0.4	-0.4	0.5
Worry (Nagel 2018)	0.2	0.5	0.8	-0.4	0.5	-0.4	0.9	0.8	0.5	0.8	0.8
Reaction Time	0.2	0.4	1.3	-0.6	0.9	-0.6	0.5	-0.1	0.1	-0.6	1.1
Blood White Count	0.2	1.5	5.3	1.2	0.7	-0.9	0.1	-0.8	0.9	-2.3	-1.5
Systolic Blood Pressure	0.2	1.1	2.9	-1.7	-0.5	-1.1	-0.3	-1.0	-0.1	-1.5	-1.1
Neuroticism	0.2	0.6	1.3	-1.1	0.4	-1.1	0.8	0.0	0.0	-0.3	1.1
Tanning	0.2	2.2	7.8	1.7	1.1	0.9	1.4	1.0	1.4	0.1	-2.8
Number of treatments/medications taken	0.2	0.3	1.1	-1.0	1.1	-0.2	0.1	0.1	0.3	-0.2	-0.5
Vitamin and mineral supplements	0.2	0.2	0.9	-1.0	0.1	0.3	0.1	-0.1	0.5	-0.8	-0.2
Pain all over the body in last month	0.2	0.2	0.9	0.2	0.2	0.9	-0.1	0.4	0.2	0.4	0.4
Fluid intelligence score	0.2	0.5	2.2	-0.1	-1.5	-0.3	-1.2	-0.3	-0.4	0.0	-0.0
Neuroticism score	0.2	0.3	1.5	-0.6	0.1	-0.7	0.5	-0.2	-0.0	-0.3	1.2
Father’s age at death	0.2	0.2	0.4	-0.2	-0.4	0.6	-0.5	-0.6	-0.4	-0.2	-0.6
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	0.4	0.3	-0.2	-0.4	-0.6	-0.3	-0.4	0.6	0.6
Birth weight of first child	0.2	0.3	1.1	1.1	-0.3	0.1	-0.5	-0.5	-0.2	-0.8	-0.6
Birth weight	0.2	0.3	1.6	0.5	-0.1	-0.3	0.6	0.5	-0.2	0.3	-1.3
Health satisfaction	0.2	0.3	0.7	-0.2	-0.1	-0.9	-0.8	0.1	-0.2	-0.1	0.8
Mouth/teeth dental problems: Loose teeth	0.2	0.2	1.0	0.3	-0.7	-0.4	-0.4	-0.2	-0.3	-1.0	-0.1
Medication: Blood pressure	0.2	0.4	1.8	1.4	-0.5	0.1	-0.6	-0.0	-0.5	-0.3	-0.8
Medication: Ibuprofen	0.2	0.3	0.6	0.3	0.2	0.4	-0.6	-0.6	-0.5	-0.5	0.8
Heart disease (mother)	0.2	0.3	0.8	0.3	0.3	-0.1	-0.3	0.9	0.8	0.8	0.1
Overall health rating	0.2	0.4	2.3	-0.2	0.9	-1.5	-0.1	0.3	0.0	-0.1	0.3
Miserableness	0.2	0.4	2.2	-0.2	0.5	-1.5	0.3	0.5	0.3	0.4	0.3
Mother’s age at death	0.2	0.2	0.6	-0.2	0.2	0.4	0.7	0.3	0.8	0.7	0.1
Tinnitus: Yes, now most or all of the time	0.2	0.3	1.6	-0.4	-0.1	-0.7	-0.2	-0.1	-0.2	-0.0	1.2
Commuting to job workplace: Public transport	0.2	0.2	0.6	0.1	-0.5	-0.8	-0.4	-0.5	-0.2	0.1	-0.5
Ever had prostate specific antigen (PSA) test	0.2	0.2	1.3	0.0	-0.1	-0.0	-0.3	-0.4	0.0	-1.1	-0.4
Diastolic blood pressure, automated reading	0.2	0.5	2.2	-0.1	0.4	-1.5	0.3	0.7	1.0	-0.5	-0.5
Depressed Affect (Nagel 2018)	0.1	0.3	0.9	-0.7	0.3	-0.9	0.4	0.1	-0.3	-0.5	0.5
Hair Pigment	0.1	1.8	4.8	0.6	2.1	0.1	1.7	1.2	2.2	-0.2	0.6
Frequency of depressed mood in last 2 weeks	0.1	0.1	0.5	-0.2	-0.1	-0.2	0.0	-0.4	-0.2	-0.4	0.7
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.2	0.3	-0.6	0.4	-0.2	0.3	-0.2	0.3	-0.6	-0.5
Alcohol usually taken with meals	0.1	0.2	0.4	-0.6	-0.2	-0.5	-0.6	-0.1	-0.1	0.3	0.2
Time employed in main current job	0.1	0.1	0.4	0.2	-0.2	-0.4	-0.1	0.1	0.1	0.6	-0.7
Pulse wave Arterial Stiffness index	0.1	0.1	0.5	0.0	-0.2	-0.2	-0.7	0.0	0.4	0.0	0.4
Pulse wave peak to peak time	0.1	0.1	0.3	0.4	0.3	0.0	0.6	-0.2	-0.4	-0.3	-0.5
Suffer from ‘nerves’	0.1	0.2	0.7	0.8	0.2	-0.1	0.8	0.2	0.4	-0.0	0.3
Mood swings	0.1	0.2	0.7	0.9	0.4	0.5	0.5	0.4	0.2	-0.2	-0.0
Back pain experienced in last month	0.1	0.1	0.6	-0.2	-0.0	0.4	-0.3	-0.2	0.0	-0.4	0.8
Number of self-reported non-cancer illnesses	0.1	0.1	0.3	-0.3	0.2	0.4	-0.1	0.2	0.6	0.4	0.2
Number of operations (self-reported)	0.1	0.2	0.9	0.3	-0.2	-0.7	0.1	-0.1	-0.3	0.9	-0.3
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0

Hub : Genes

DNASE2

Models

Trait associations