TWAS hub - DNMBP

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0820	0.0250	1.4e-07	0.054	0.066	0.072	0.065	0.070	3.1e-07	1.7e-08	4.1e-09	2.5e-08	7.0e-09
2	GTEx	Adipose Visceral Omentum	0.0870	0.0420	4.3e-03	0.062	NA	0.066	NA	0.063	3.9e-04	NA	2.5e-04	NA	3.4e-04
3	GTEx	Artery Tibial	0.2510	0.0484	4.7e-14	0.231	NA	0.227	NA	0.234	5.3e-18	NA	9.9e-18	NA	2.6e-18
4	GTEx	Brain Cerebellar Hemisphere	0.2830	0.1010	6.9e-04	0.102	NA	0.135	NA	0.113	1.4e-03	NA	2.5e-04	NA	8.1e-04
5	GTEx	Brain Cerebellum	0.3260	0.1120	8.7e-04	0.017	NA	0.087	NA	0.069	1.0e-01	NA	1.5e-03	NA	4.5e-03
6	GTEx	Esophagus Gastroesophageal Junction	0.1410	0.0570	2.4e-03	0.048	NA	0.001	NA	0.013	7.8e-03	NA	2.8e-01	NA	1.0e-01
7	GTEx	Heart Atrial Appendage	0.1090	0.0520	7.3e-03	0.019	NA	-0.006	NA	0.003	4.6e-02	NA	9.8e-01	NA	2.2e-01
8	GTEx	Lung	0.1056	0.0341	1.2e-05	0.087	NA	0.027	NA	0.061	3.6e-07	NA	3.8e-03	NA	1.9e-05
9	GTEx	Nerve Tibial	0.0867	0.0398	7.6e-03	0.060	NA	0.018	NA	0.059	4.5e-05	NA	1.9e-02	NA	5.5e-05
10	GTEx	Ovary	0.2800	0.1130	2.1e-03	0.140	NA	0.031	NA	0.112	2.7e-04	NA	5.8e-02	NA	1.1e-03
11	GTEx	Pituitary	0.4020	0.1070	2.1e-03	-0.001	NA	-0.005	NA	-0.012	3.5e-01	NA	4.5e-01	NA	9.8e-01
12	GTEx	Testis	0.2090	0.0680	3.4e-04	0.064	NA	0.076	NA	0.094	8.2e-04	NA	3.0e-04	NA	5.7e-05
13	GTEx	Thyroid	0.3550	0.0640	0.0e+00	0.349	NA	0.322	NA	0.334	1.1e-27	NA	3.5e-25	NA	2.5e-26
14	TCGA	Kidney Renal Clear Cell Carcinoma	0.1747	0.0513	2.8e-09	0.064	0.094	0.083	NA	0.058	9.6e-08	1.0e-10	1.2e-09	NA	3.8e-07
15	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0730	0.0370	9.8e-04	0.033	0.026	0.019	NA	0.035	5.4e-03	1.3e-02	2.6e-02	NA	4.1e-03
16	TCGA	Ovarian Serous Cystadenocarcinoma	0.1070	0.0510	3.6e-04	0.056	0.065	0.059	NA	0.051	1.2e-04	3.4e-05	8.2e-05	NA	2.3e-04
17	TCGA	Thyroid Carcinoma	0.1190	0.0420	7.7e-07	0.072	0.071	0.066	NA	0.069	1.6e-07	1.9e-07	5.6e-07	NA	3.0e-07

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17
Osteoporosis (self-reported)	5.0	6.2	12.6	-3.3	-2.9	-3.0	-1.1	-2.7	-2.7	-3.0	-3.6	-2.3	-2.7	-0.4	3.4	-2.7	-0.1	-2.5	-1.2	-1.0
Headache pain in last month	4.9	8.3	15.6	3.4	3.5	3.6	1.9	2.7	2.8	3.4	3.9	2.9	3.2	0.5	-3.5	3.2	1.0	2.9	2.0	2.0
Pulse rate, automated reading	4.5	14.5	32.2	5.7	3.3	4.5	4.2	5.5	5.4	4.2	4.6	2.5	3.7	1.6	-4.6	2.6	-0.7	3.9	1.3	0.9
Number of operations (self-reported)	3.3	4.9	10.8	1.6	1.5	2.3	2.0	2.3	0.8	2.5	2.3	1.8	2.9	0.5	-2.7	1.8	1.9	3.1	2.1	3.3
Supplements: Calcium	3.1	3.4	9.4	-2.9	-2.3	-1.8	-1.5	-2.1	-3.1	-1.6	-2.1	-2.2	-1.9	-1.0	1.9	-1.8	0.1	-0.9	-1.2	0.0
Major Depression (MDD)	3.0	3.6	9.3	3.0	2.3	2.4	2.1	2.4	2.5	2.0	2.0	1.5	1.7	0.5	-2.0	1.6	-0.2	1.4	1.5	-0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	3.0	3.6	7.5	-0.5	-2.3	-2.0	0.4	-0.6	0.3	-2.3	-2.4	-2.2	-2.6	0.2	1.2	-2.1	-2.7	-2.5	-1.5	-2.6
Verbal and Numeric Reasoning (VNR)	2.9	7.1	12.9	3.6	3.1	3.0	3.1	3.2	3.3	2.8	2.7	2.8	2.8	1.1	-1.8	3.0	1.5	2.2	2.3	1.1
Exposure to tobacco smoke outside home	2.8	3.7	7.2	1.2	2.7	2.5	-0.4	0.6	0.1	2.5	2.1	2.5	2.5	1.1	-1.3	2.5	2.0	2.1	2.3	1.4
Fractured/broken bones in last 5 years	2.7	3.5	9.1	2.2	1.9	1.9	0.2	2.0	2.3	1.5	1.1	2.1	2.1	-2.0	0.0	2.2	1.8	1.3	3.0	1.5
Fluid intelligence score	2.6	5.5	8.6	2.9	2.8	2.6	2.9	2.5	2.7	2.5	2.3	2.6	2.5	0.4	-0.9	2.8	1.9	1.9	2.4	1.3
Hypothyroidism/myxoedema (self-reported)	2.6	5.1	14.6	-0.9	-2.2	-2.4	0.1	-0.4	-0.2	-2.7	-2.5	-2.5	-3.0	0.0	0.5	-2.2	-3.8	-2.9	-2.6	-3.4
Diverticular disease/diverticulitis (self-reported)	2.4	2.9	10.2	2.6	1.8	1.8	1.2	2.4	3.2	1.5	1.4	1.9	1.8	0.7	0.4	1.4	0.7	1.2	1.5	0.3
Medication: Levothyroxine sodium	2.4	4.1	8.2	-1.0	-1.8	-2.2	-1.4	-1.4	-0.4	-2.5	-2.5	-2.0	-2.6	-0.3	1.8	-1.7	-2.7	-2.8	-1.8	-2.9
Qualifications: A levels/AS levels or equivalent	2.4	5.3	11.1	2.9	3.3	2.7	0.8	2.0	2.7	2.5	2.8	3.1	2.7	-0.2	-1.2	3.0	1.4	1.8	2.0	0.8
Ever highly irritable/argumentative for 2 days	2.4	2.9	5.8	1.7	2.4	2.0	2.0	1.6	0.9	2.0	2.2	1.7	1.7	0.8	-1.6	2.3	0.3	1.3	1.9	0.7
LDL Cholesterol	2.2	3.4	5.8	2.0	2.2	2.3	1.1	1.6	0.8	1.9	2.0	2.2	2.4	-1.5	-0.5	2.1	1.7	2.2	1.5	2.2
Gout (self-reported)	2.2	3.0	5.5	-1.7	-2.1	-2.0	-2.0	-1.3	-1.5	-2.0	-1.9	-2.1	-2.0	-0.4	1.1	-2.0	-1.5	-1.5	-2.3	-0.9
Shortness of breath walking on level ground	2.2	2.6	7.3	1.7	2.2	1.7	1.3	2.7	0.9	1.6	1.4	2.0	1.8	0.9	-2.3	1.8	0.4	1.0	1.2	0.4
Frequency of depressed mood in last 2 weeks	2.1	2.9	5.0	2.2	2.1	1.7	1.8	2.1	1.9	1.5	1.8	1.9	1.7	0.5	-2.0	1.8	1.2	1.4	0.3	1.7
Health satisfaction	2.1	2.8	9.3	2.0	1.8	1.8	2.4	3.1	1.2	1.6	1.4	1.2	1.4	1.4	-2.4	1.3	-0.6	1.1	1.0	-0.4
Intelligence (Savage-Jansen 2018)	2.0	6.3	12.1	3.4	2.8	2.5	2.9	3.2	3.5	2.4	2.3	3.0	2.9	-0.0	-1.7	2.6	1.7	2.2	1.8	1.4
Pain all over the body in last month	2.0	2.2	4.6	-1.3	-1.7	-1.5	-0.8	-1.2	-0.9	-1.9	-1.8	-1.8	-1.6	-0.3	1.1	-1.6	-1.6	-1.6	-1.1	-2.1
Hayfever/allergic rhinitis (self-reported)	2.0	2.7	6.8	2.6	2.0	2.1	1.2	1.8	2.1	1.8	1.6	1.7	1.9	0.3	-1.1	1.7	0.2	1.3	1.6	0.3
Medication: Simvastatin	2.0	2.9	5.4	-2.3	-2.3	-2.1	-1.7	-1.8	-2.2	-1.7	-1.9	-1.8	-1.9	-0.1	1.3	-2.0	-0.0	-1.1	-1.9	-0.3
Average weekly spirits intake	1.9	2.3	5.2	1.9	2.3	1.9	0.0	1.0	1.6	1.8	1.9	1.9	1.3	0.8	-1.4	2.2	0.7	1.2	1.5	0.6
Average weekly fortified wine intake	1.9	2.3	6.1	1.9	2.5	1.7	1.4	1.7	0.8	1.3	1.6	2.1	1.3	0.8	-1.3	2.1	-0.1	0.5	1.5	-0.6
Medication: Ramipril	1.9	2.5	5.2	1.8	1.8	1.9	0.5	1.6	1.6	1.9	2.3	1.7	1.9	0.1	-1.3	1.5	0.8	1.8	1.4	1.4
Tense / ‘highly strung’	1.9	3.2	5.6	-1.9	-2.0	-2.0	-0.5	-1.7	-1.5	-1.7	-1.6	-2.2	-2.3	0.7	1.3	-2.4	-2.0	-1.6	-2.2	-1.5
Birth weight	1.9	4.2	10.2	1.9	1.6	2.5	1.0	1.6	1.6	2.6	2.7	1.4	2.4	0.9	-2.0	1.8	1.6	3.2	1.6	2.6
Eye problems/disorders: None of the above	1.9	2.2	4.2	-1.4	-1.2	-1.6	-0.4	-1.7	-1.3	-1.7	-1.5	-1.3	-1.6	1.6	1.6	-1.2	-1.2	-2.0	-0.7	-2.1
Medication: Omeprazole	1.9	2.2	5.7	1.4	1.8	2.0	0.3	0.9	-0.1	2.4	2.3	1.4	2.0	1.2	-1.0	1.2	0.5	2.3	0.5	1.0
Chronic bronchitis/emphysema (father)	1.8	2.2	3.7	-1.5	-1.6	-1.5	-1.8	-1.4	-1.3	-1.2	-1.4	-1.7	-1.9	-1.6	1.1	-1.4	-1.4	-1.2	-1.7	-0.5
Medication for pain relief, constipation, heartburn	1.8	3.1	6.8	-1.5	-2.0	-2.6	-1.3	-1.4	-0.2	-2.5	-2.4	-1.2	-2.0	-1.8	2.1	-1.5	-0.2	-2.6	-1.4	-0.2
Alcohol drinker status: Never	1.8	2.1	4.8	0.6	1.5	1.8	0.2	-0.3	0.3	2.1	2.2	1.4	2.1	1.0	-0.9	1.2	1.7	2.1	1.6	1.2
Irritability	1.8	3.1	7.9	2.8	2.1	2.1	1.0	2.2	2.1	2.1	2.3	1.4	1.4	2.0	-1.6	1.2	-0.8	1.8	0.0	-0.1
Hypothyroidism (self reported)	1.7	3.9	10.1	-1.2	-1.7	-2.2	0.2	-0.7	-0.9	-2.4	-1.9	-2.0	-2.7	0.5	1.1	-1.8	-3.2	-2.8	-2.6	-2.4
Diabetes (father)	1.7	2.1	7.0	-0.6	-1.2	-0.9	0.8	-0.4	-0.2	-1.3	-1.2	-1.6	-1.7	2.1	0.4	-1.6	-2.3	-1.6	-1.0	-2.6
Prospective memory result	1.7	2.1	4.5	-2.0	-2.1	-1.4	-0.8	-1.5	-2.0	-1.2	-1.2	-2.1	-1.5	-0.0	0.9	-1.9	-1.5	-0.7	-1.4	-0.2
Had other major operations	1.6	2.0	4.8	1.3	0.8	1.3	1.4	1.5	1.4	1.3	1.5	1.1	1.9	0.6	-1.7	0.8	1.1	2.0	1.3	2.2
Average weekly beer plus cider intake	1.6	2.3	3.9	-1.5	-1.7	-1.5	-1.5	-1.4	-1.5	-1.2	-1.0	-2.0	-1.9	1.5	0.2	-1.7	-1.7	-1.3	-1.9	-1.4
Lung FEV1/FVC ratio	1.5	7.4	20.7	1.7	3.0	3.0	1.2	0.5	0.9	3.0	2.9	3.6	3.7	0.4	0.5	3.2	3.6	2.7	4.5	2.5
Neuroticism	1.5	3.7	6.9	2.3	2.2	2.4	1.2	2.3	1.4	2.3	2.3	1.8	2.1	1.0	-2.6	1.8	0.9	2.2	0.7	1.4
Stomach or abdominal pain in last month	1.5	1.9	3.8	1.5	1.9	1.8	0.6	1.1	0.7	1.7	1.5	1.6	1.7	-0.4	-0.7	1.9	1.0	1.2	1.9	0.2
Alcohol usually taken with meals	1.5	2.4	4.8	1.2	1.8	1.5	-0.7	0.8	0.5	1.6	1.4	2.0	1.8	-1.3	-0.8	1.9	1.9	1.5	1.7	2.2
Heart disease (mother)	1.5	1.8	6.2	-1.1	-1.1	-1.1	0.9	0.6	-1.2	-1.2	-0.9	-1.5	-1.4	-0.2	-0.8	-1.6	-2.5	-1.1	-2.1	-1.6
Leg pain on walking	1.5	1.9	6.9	1.7	1.3	1.5	1.6	2.0	1.3	1.1	1.4	0.7	1.2	-0.3	-2.6	1.2	-0.0	1.3	0.5	1.1
Ever had bowel cancer screening	1.5	1.8	6.8	-1.3	-0.7	0.4	-2.6	-2.1	-1.7	0.6	-0.0	-0.4	0.7	-0.4	1.8	-0.2	1.6	1.6	1.5	1.4
Prostate Cancer	1.4	2.0	4.3	-0.8	-1.6	-1.3	-1.9	-1.2	0.1	-1.5	-1.5	-2.1	-2.0	0.3	1.0	-1.4	-1.6	-1.3	-1.4	-1.3
Age at First Birth	1.4	2.0	5.4	2.3	1.6	1.6	0.6	2.1	1.9	1.3	1.5	1.4	1.3	-0.8	-0.5	1.6	0.6	1.2	0.9	1.1
Glaucoma (self-reported)	1.4	1.7	2.9	1.6	1.6	1.7	0.6	1.4	1.7	1.6	1.5	1.1	1.3	0.4	-1.6	1.4	-0.0	1.3	1.0	-0.1
Migraine (self-reported)	1.4	1.7	4.5	1.3	1.6	1.9	0.6	0.0	0.6	2.0	2.1	1.1	1.3	2.0	-0.4	1.2	-0.1	1.4	1.1	-0.4
Depression (Nagel 2018)	1.3	2.0	5.4	1.9	1.6	1.4	2.0	2.3	1.6	1.2	1.3	1.6	1.4	0.5	-1.4	1.2	0.9	1.1	0.1	1.1
Systolic Blood Pressure	1.3	6.6	11.8	3.2	2.8	2.9	1.6	3.2	2.8	2.8	3.4	2.3	2.5	-2.4	-3.0	2.7	0.6	2.5	1.0	1.9
Commuting to job workplace: Car/motor vehicle	1.3	1.4	3.0	-1.0	-1.2	-1.5	0.4	-0.4	-0.9	-1.7	-1.7	-1.3	-1.5	0.1	0.5	-1.3	-1.3	-1.6	-1.5	-0.9
Back pain experienced in last month	1.3	1.9	5.6	0.9	2.1	1.5	1.0	0.5	0.0	1.4	1.4	2.0	1.5	-0.5	-0.3	2.4	1.5	0.7	1.7	1.0
Pain type(s) experienced in last month: Hip pain	1.3	1.6	4.9	2.0	1.3	1.4	2.0	2.2	1.7	0.9	1.4	1.0	0.9	0.5	-1.1	1.1	-0.5	0.6	0.4	0.2
Mean Putamen Volume	1.2	1.4	5.5	0.4	0.6	1.3	-0.1	0.0	0.0	1.9	1.6	0.3	1.2	0.1	-0.5	0.6	1.2	2.4	0.7	2.2
Lupus	1.2	1.8	5.0	-0.7	-0.9	-1.1	-1.0	-1.2	0.6	-1.7	-2.2	-1.1	-1.4	-1.9	1.9	-0.7	-0.3	-2.0	0.8	-1.6
Type 2 Diabetes (T2D) (2012)	1.2	1.4	5.1	-0.6	-0.8	-1.0	-0.2	-1.4	-0.7	-1.1	-1.1	-0.8	-1.1	1.1	2.3	-1.3	-1.6	-1.6	-0.5	-1.5
Supplements: Zinc	1.2	1.3	3.3	-1.1	-1.5	-1.0	0.5	-1.5	-1.3	-0.8	-0.9	-1.5	-1.2	0.0	0.8	-1.8	-1.2	-0.6	-1.1	-1.1
Multivitamins +/- minerals	1.2	1.5	4.2	0.1	0.9	1.1	-1.6	-0.6	-0.0	1.3	1.1	0.8	1.3	-2.1	0.0	1.2	1.8	1.6	1.2	1.4
Alcohol intake versus 10 years previously	1.2	1.7	5.7	-0.4	-1.0	-1.6	-0.7	-0.5	1.2	-2.0	-1.8	-0.6	-1.4	0.5	1.4	-1.0	-1.1	-2.4	-0.6	-1.8
Medication: Ibuprofen (e.g. Nurofen)	1.2	1.6	3.1	0.8	1.8	1.7	1.7	1.5	0.0	1.3	1.0	1.4	1.2	0.7	-0.8	1.6	0.9	1.0	1.7	0.5
Mouth/teeth dental problems: Bleeding gums	1.2	1.5	3.1	1.3	1.6	1.5	1.5	1.3	0.5	1.4	1.2	1.2	1.1	1.8	-0.8	1.5	-0.0	1.1	1.4	0.2
High blood pressure (siblings)	1.2	1.7	5.8	1.7	0.6	1.3	1.6	2.4	1.5	1.3	1.4	0.2	1.0	-0.3	-2.4	0.6	-0.5	1.4	0.0	0.3
Reason for reducing amount of alcohol drunk: Health precaution	1.2	1.4	3.7	-1.4	-1.9	-1.2	-0.5	-0.4	-1.5	-1.3	-1.3	-1.8	-1.2	0.3	0.1	-1.8	-0.8	-0.7	-1.0	-0.7
Medication: Omeprazole (e.g. Zanprol)	1.2	1.4	4.2	0.9	1.1	1.6	0.3	0.8	-0.4	2.0	1.9	0.6	1.3	1.8	-1.0	0.5	-0.0	2.0	0.0	0.4
Alzheimer’s Disease (in father)	1.1	1.2	3.9	-1.8	-0.8	-1.2	-0.4	-0.5	-2.0	-1.1	-0.7	-0.4	-0.6	-0.3	0.3	-1.6	-1.0	-0.8	-1.7	-0.8
Other serious medical condition/disability diagnosed by doctor	1.1	1.4	3.2	-1.3	-1.4	-1.5	-0.4	-0.9	-0.8	-1.6	-1.8	-1.2	-1.5	0.2	0.1	-1.4	-0.8	-1.3	-1.3	-1.1
Time employed in main current job	1.1	1.3	3.4	0.8	1.6	0.7	1.0	0.4	1.6	0.8	0.9	1.9	1.0	-0.4	0.7	1.5	1.8	0.1	1.2	1.3
Seen doctor (GP) for nerves, anxiety, tension or depression	1.1	1.7	5.6	2.4	1.8	1.3	0.9	1.8	1.7	1.0	1.6	1.1	1.0	-0.5	-1.7	1.4	-0.5	0.7	-0.2	0.4
Medication: Allopurinol	1.1	1.5	3.8	-1.5	-1.9	-1.3	-1.2	-1.4	-1.0	-1.2	-1.2	-2.0	-1.3	-0.6	0.4	-1.5	-0.6	-0.3	-1.4	-0.1
Medication: Seretide 50 evohaler	1.1	1.3	4.0	-1.7	-0.8	-1.1	-1.5	-2.0	-1.9	-0.9	-1.2	-0.4	-0.8	0.3	1.7	-0.9	0.8	-0.8	0.1	0.0
Illnesses of father: Heart disease	1.1	1.5	3.6	1.9	0.8	1.5	-0.5	1.7	1.7	1.4	1.6	0.5	1.3	-0.1	-1.6	0.8	-0.2	1.9	0.0	0.8
Handedness (chirality/laterality): Left-handed	1.1	1.3	3.8	1.0	0.8	1.6	-0.2	1.3	0.4	1.6	1.6	0.6	1.4	0.3	-1.5	0.8	0.6	1.9	0.5	1.1
Cholesterol lowering medication	1.1	1.7	6.5	-1.8	-1.7	-1.2	0.1	-0.0	-2.5	-0.8	-0.8	-1.6	-1.0	1.2	-0.8	-1.6	-0.7	-0.1	-2.0	0.2
Eye problems/disorders: Diabetes related eye disease	1.0	1.1	8.8	-0.9	-0.8	-0.9	-1.6	0.3	-0.7	-0.9	-1.1	-0.4	-0.3	-3.0	0.1	-0.7	0.2	-0.5	-0.9	0.6
Angina	1.0	1.3	3.6	1.1	0.8	1.4	1.1	0.8	0.5	1.3	1.1	0.6	1.3	-0.2	0.2	1.1	1.0	1.9	1.2	1.9
Number of incorrect matches in round	1.0	1.7	5.6	-1.9	-1.9	-0.7	-1.0	-1.4	-1.8	-0.6	-0.7	-2.4	-1.0	1.3	-1.2	-1.7	-0.5	0.3	-0.9	-1.0
Hearing difficulty/problems with background noise	1.0	1.6	4.1	2.0	1.7	1.6	0.1	0.4	1.7	1.5	1.4	1.4	1.3	0.4	-0.1	1.5	0.9	1.2	1.4	0.2
Pulse rate	1.0	1.6	5.7	1.9	0.4	1.0	1.1	1.5	2.4	0.7	0.9	-0.3	0.5	2.0	-1.4	0.0	-1.9	0.5	0.1	-1.7
Qualifications: O levels/GCSEs or equivalent	1.0	1.6	3.5	1.9	1.6	1.4	0.8	1.6	1.8	1.3	1.3	1.5	1.4	0.5	-1.1	1.2	0.3	1.1	1.0	0.4
Pulse wave peak to peak time	1.0	1.2	2.5	-1.6	-1.4	-1.4	-1.2	-1.3	-0.9	-1.3	-1.5	-0.9	-1.2	0.1	0.9	-1.1	0.9	-1.1	-0.6	-0.3
Medication: Aspirin	1.0	1.3	4.5	0.1	0.8	1.3	-0.2	0.5	-1.1	1.7	1.2	0.7	1.6	0.4	-1.6	0.6	1.2	2.1	1.0	1.1
Qualifications: nursing, teaching	1.0	1.5	3.7	1.1	1.6	1.5	0.2	0.5	0.5	1.6	1.4	1.6	1.7	-0.3	-0.3	1.4	1.0	1.4	1.9	0.8
Mineral and other dietary supplements	1.0	1.3	10.0	1.0	1.0	0.3	3.2	1.6	1.4	0.1	0.3	1.2	0.4	1.8	-0.6	0.8	0.1	-0.4	0.5	-0.0
Illnesses of father: None of the above (group 1)	1.0	1.2	4.7	0.1	1.2	0.4	0.2	-0.5	0.0	0.3	-0.0	1.6	1.1	-1.3	1.0	1.6	2.2	0.1	1.8	1.3
Eye problems/disorders: Glaucoma	1.0	1.2	3.3	1.3	0.7	1.3	0.8	1.2	1.5	1.4	1.5	0.2	0.8	0.9	-1.8	0.4	-1.0	1.3	0.2	-0.7
Height	0.9	17.8	28.7	-4.8	-4.6	-4.6	-1.6	-4.9	-4.4	-4.6	-5.0	-4.4	-5.2	2.1	4.3	-4.1	-2.4	-5.4	-1.4	-4.5
Hair/balding pattern: Pattern 2	0.9	1.1	5.3	-0.3	0.5	0.4	0.1	0.1	-0.6	0.6	0.7	1.2	1.4	-1.0	0.7	0.9	2.3	1.1	1.0	2.1
Qualifications: None of the above	0.9	1.9	4.1	-1.1	-1.2	-1.4	1.0	-1.6	-0.8	-1.5	-1.5	-1.6	-1.8	1.3	0.6	-1.0	-1.0	-1.9	-1.2	-2.0
Mouth/teeth dental problems	0.9	1.4	6.5	-0.6	0.6	-0.1	-1.5	-0.2	-0.4	0.3	0.4	1.4	0.8	-2.4	0.8	1.0	2.5	0.1	1.0	1.8
Mouth/teeth dental problems: Dentures	0.9	1.6	6.9	0.1	-1.6	-0.7	-0.2	-0.2	0.7	-1.0	-1.0	-2.2	-1.3	0.7	-0.4	-1.6	-2.6	-0.4	-1.7	-1.3
Pulse wave Arterial Stiffness index	0.9	1.0	2.0	1.4	1.3	1.2	1.3	1.1	0.7	1.1	1.4	0.8	1.0	0.0	-0.8	1.0	-0.9	0.9	0.5	0.2
Breastfed as a baby	0.9	1.1	4.7	0.9	0.6	1.3	0.5	0.5	0.2	1.4	1.3	0.0	0.9	2.1	-2.2	0.4	0.1	1.4	0.5	0.3
Worry too long after embarrassment	0.9	1.6	3.2	1.5	1.3	1.6	-0.3	1.2	1.2	1.6	1.6	0.8	1.3	0.2	-1.5	1.2	0.7	1.8	-0.0	1.6
Angina (self-reported)	0.9	1.2	3.3	1.1	0.8	1.3	1.0	0.8	0.5	1.2	1.0	0.6	1.2	-0.5	0.3	1.1	1.0	1.7	1.2	1.8
Alcohol intake frequency.	0.9	2.1	5.2	1.3	1.4	1.4	1.1	1.8	2.3	1.3	1.6	1.5	2.0	-0.7	-1.1	1.2	1.2	1.4	1.4	1.0
Supplements: Fish oil (including cod liver oil)	0.9	1.2	8.8	-1.3	-0.5	-0.2	-3.0	-1.6	-2.0	0.3	-0.1	-0.7	-0.1	-1.2	0.2	-0.4	0.3	0.4	-0.3	0.3
Medication: Atorvastatin	0.9	1.1	5.2	0.5	-0.8	0.0	-0.6	1.1	-0.1	0.0	0.0	-1.5	-0.5	1.3	-1.2	-0.9	-2.3	0.5	-1.9	-0.9
Basal cell carcinoma (self-reported)	0.9	1.1	3.4	-1.3	-1.4	-0.9	-0.9	-1.8	-1.3	-0.7	-0.9	-1.4	-1.1	-0.1	1.4	-1.2	-0.4	-0.5	-0.5	-0.4
Heart attack/myocardial infarction (self-reported)	0.9	1.1	3.5	1.2	0.8	1.5	0.5	0.9	0.8	1.5	1.4	0.4	1.3	1.2	-1.2	0.5	0.3	1.9	0.1	0.5
Bipolar Disorder (2011)	0.8	0.8	2.3	-1.4	-0.9	-0.9	-0.2	-1.1	-1.5	-0.8	-1.0	-0.7	-0.8	0.3	1.1	-0.8	-0.3	-0.7	-0.1	-1.0
Rheumatoid Arthritis	0.8	1.1	5.8	0.3	0.5	0.6	1.0	0.3	0.5	0.8	0.7	0.9	0.7	-1.9	-0.4	1.1	1.4	1.0	0.9	2.4
Vitamin and mineral supplements	0.8	1.1	3.3	-0.2	-0.8	-1.2	1.8	0.3	0.3	-1.2	-1.0	-0.6	-1.3	1.4	0.2	-0.9	-1.2	-1.4	-1.2	-0.8
Relative age voice broke	0.8	1.2	3.2	-1.0	-1.6	-0.7	-0.9	-1.2	-1.3	-0.3	-0.3	-1.7	-0.9	1.4	0.6	-1.8	-1.0	0.1	-1.1	-0.5
Happiness	0.8	1.0	2.5	-0.9	-0.3	-1.0	0.8	0.2	-1.4	-1.3	-1.0	-0.5	-1.0	0.8	-0.2	-0.6	-1.6	-1.5	-0.9	-1.3
Lung cancer (father)	0.8	1.0	3.4	-1.7	-1.0	-0.7	-0.3	-1.1	-1.8	-0.8	-1.2	-0.7	-0.7	1.1	1.0	-0.6	0.1	-0.9	0.3	-1.0
Illnesses of mother	0.8	1.0	2.9	1.5	0.9	1.1	0.9	0.8	1.7	0.9	0.9	0.7	0.9	1.1	-0.6	1.1	0.6	0.9	0.9	0.5
Medication: Ibuprofen	0.8	0.9	2.3	0.5	1.2	1.3	1.4	1.5	-0.3	1.0	0.5	0.9	0.9	0.5	-1.0	1.1	0.5	0.9	1.3	0.3
Family relationship satisfaction	0.8	1.0	2.5	0.8	1.6	1.1	0.3	0.6	0.3	1.1	1.2	1.5	1.2	0.7	0.4	1.0	1.3	0.8	0.8	0.4
Average weekly red wine intake	0.8	1.2	3.4	0.3	0.6	0.8	0.9	1.3	-0.6	1.1	0.9	1.1	1.4	-0.5	-1.8	0.6	1.3	1.6	0.1	1.8
Breast cancer (self-reported)	0.8	1.0	2.4	1.3	1.6	0.9	0.9	0.3	1.3	0.7	1.2	1.2	0.8	0.2	-1.4	1.3	-0.5	0.1	0.7	-0.4
Medication: Aspirin	0.8	1.0	3.8	-0.4	0.3	0.9	-0.7	-0.0	-1.6	1.3	0.9	0.3	1.3	0.5	-1.6	0.2	1.0	2.0	0.4	1.0
Ulcerative Colitis (UC)	0.7	1.3	2.5	-1.2	-0.8	-1.3	-0.2	-0.2	-1.6	-1.1	-1.4	-0.9	-1.5	-0.5	1.6	-1.0	-1.3	-1.3	-1.0	-1.3
HDL Cholesterol	0.7	1.2	2.7	0.8	1.3	0.7	1.0	1.4	0.2	0.9	1.1	1.3	1.1	-1.2	-1.6	1.5	0.3	0.9	-0.0	1.5
Blood Red Count	0.7	6.6	18.6	-0.8	-1.6	-2.9	-2.3	-1.1	-1.0	-2.9	-2.2	-1.9	-3.1	0.2	1.8	-2.1	-4.2	-3.4	-4.3	-3.5
Waist Hip Ratio (WHR)	0.7	3.1	8.4	-0.2	-1.4	-2.0	-0.5	0.2	1.1	-2.5	-2.2	-1.4	-2.2	0.2	1.0	-1.6	-2.3	-2.9	-1.7	-2.6
Fed-up feelings	0.7	1.4	2.8	1.7	1.3	1.5	1.5	1.1	1.2	1.4	1.3	0.7	1.1	0.8	-1.0	1.1	0.3	1.5	0.5	0.9
Heart attack	0.7	0.9	2.6	1.1	0.6	1.3	0.5	1.1	0.9	1.3	1.2	0.2	1.1	1.1	-1.3	0.3	0.1	1.6	-0.1	0.3
Neuroticism score	0.7	1.5	5.3	1.6	1.0	1.5	0.6	1.2	1.1	1.5	1.6	0.4	1.1	0.9	-2.3	0.6	-0.1	1.7	-0.3	0.8
Peak expiratory flow (PEF)	0.7	1.6	5.4	0.4	1.0	1.1	-0.1	-1.1	0.1	1.2	1.1	1.3	1.3	0.0	2.3	1.2	1.9	1.1	2.3	1.1
Loud music exposure frequency	0.7	0.8	3.9	-0.2	-0.2	-0.3	-0.7	-0.1	-0.1	-0.3	-0.2	-0.8	-0.8	1.4	0.0	-0.6	-1.9	-0.7	-1.0	-2.0
Medication: Amlodipine	0.7	1.0	5.7	0.8	0.1	1.1	-0.6	-0.5	0.5	0.9	0.5	-1.0	-0.0	2.2	-0.2	-0.1	-1.3	0.8	0.4	-2.4
Number of full sisters	0.7	0.8	3.1	0.8	0.6	0.6	0.3	-0.3	1.1	0.6	0.7	0.7	0.8	0.4	0.9	0.9	1.8	0.8	0.7	1.7
Commuting to job workplace: Walk	0.7	0.7	4.6	-1.5	-0.5	-0.7	-1.2	-0.8	-2.1	-0.3	-0.4	-0.3	-0.6	-0.3	0.9	-0.3	0.5	-0.3	-0.5	0.3
Average weekly champagne plus white wine intake	0.7	0.9	4.8	1.5	0.8	0.7	-0.1	1.4	2.2	0.6	0.7	1.0	0.7	-1.0	-1.0	0.5	0.1	0.3	1.0	0.3
Tinnitus: Yes, now most or all of the time	0.7	0.9	3.5	-1.4	-0.7	-1.0	-1.9	-0.2	-1.3	-0.9	-0.6	-0.4	-0.5	-1.7	0.3	-0.7	0.2	-0.6	-0.4	0.8
Commuting to job workplace: Public transport	0.7	0.9	2.7	0.4	0.6	1.1	0.4	0.6	-0.2	1.3	1.6	0.6	1.1	1.2	-1.4	0.6	-0.1	1.3	0.8	0.1
Risk taking	0.7	1.0	2.5	-1.2	-0.7	-1.2	1.1	-0.6	-1.4	-1.2	-1.2	-0.6	-1.3	0.4	1.1	-0.5	-0.2	-1.6	-0.4	-0.1
Pack years of smoking	0.7	1.0	2.4	-1.0	-1.4	-1.2	-0.1	-0.5	-0.4	-1.2	-1.4	-1.6	-1.3	-0.1	1.0	-1.2	-0.4	-0.7	-1.1	0.3
Ulcerative Colitis	0.6	0.9	4.3	-1.3	-0.7	-0.9	-1.0	-0.5	-1.9	-0.6	-0.9	-0.5	-0.9	-0.1	2.1	-0.8	-0.3	-0.5	-0.5	-0.5
Smoking Status	0.6	1.4	3.3	-1.4	-1.7	-1.4	0.4	-1.1	-1.2	-1.1	-1.3	-1.6	-1.4	0.6	0.7	-1.8	-0.7	-0.5	-1.5	-0.6
Taking other prescription medications	0.6	0.9	2.4	-0.2	-1.1	-0.9	-0.6	-0.1	-0.3	-1.0	-1.2	-1.4	-1.1	0.0	0.5	-1.0	-1.4	-0.7	-1.5	-1.0
Heel bone mineral density (BMD) T-score, automated (left)	0.6	1.4	3.4	0.9	1.2	1.5	1.4	1.1	0.0	1.8	1.5	1.2	1.2	1.8	-0.7	0.8	0.8	1.5	0.4	0.4
Illnesses of siblings	0.6	0.8	3.2	-0.9	0.5	-0.1	-1.8	-1.5	-1.3	-0.2	-0.6	0.8	0.1	-0.3	1.2	0.4	0.7	-0.7	1.1	-0.4
Worrier / anxious feelings	0.6	1.2	4.5	1.1	0.8	1.6	-0.4	0.5	0.6	1.8	1.8	0.3	1.1	0.6	-1.1	0.3	-0.2	2.1	-0.1	0.8
Falls in the last year	0.6	0.8	3.0	-0.8	-0.2	-1.1	1.0	0.3	-1.0	-1.3	-1.1	0.4	-0.5	-1.7	0.3	-0.1	0.2	-1.5	-0.6	-0.3
Hair/balding pattern: Pattern 3	0.6	0.9	4.2	0.9	1.1	0.6	0.3	1.3	0.7	0.5	0.6	1.0	0.7	-0.9	-2.1	1.3	0.3	0.5	0.2	1.5
Standing height	0.6	5.6	10.7	-2.7	-2.5	-2.5	-1.3	-3.3	-2.0	-2.6	-2.9	-2.6	-3.0	0.7	2.9	-2.1	-0.7	-3.0	-0.7	-2.2
Blood clot in the leg (DVT)	0.6	0.8	3.0	-1.7	-1.1	-0.8	-0.4	-0.6	-1.4	-0.8	-0.7	-1.2	-0.7	-0.4	0.3	-1.0	-0.3	-0.6	-0.3	-0.3
Forced vital capacity (FVC), Best measure	0.6	2.2	9.1	-0.7	-1.2	-1.4	-1.5	-2.5	0.1	-1.5	-1.6	-1.3	-1.8	0.1	3.0	-0.8	-0.3	-1.8	-0.0	-1.1
Number of children fathered	0.6	0.6	3.2	-1.3	-0.9	-0.4	-1.0	-0.9	-1.8	-0.2	-0.9	-0.9	-0.4	-0.4	-0.2	-0.6	0.4	0.6	-0.4	0.4
Qualifications: College or University degree	0.6	1.9	5.0	1.2	1.9	1.3	-0.1	1.1	0.9	1.3	1.4	2.2	1.6	-0.5	-0.6	1.8	1.8	1.1	1.4	1.1
Suffer from ‘nerves’	0.6	0.9	2.9	1.1	0.5	1.3	-0.3	0.4	1.4	1.4	1.2	-0.2	0.4	1.7	-1.2	0.1	-0.0	1.4	0.3	-0.4
Illnesses of siblings: Diabetes	0.6	0.7	6.4	1.3	-0.2	-0.1	0.9	1.1	2.5	-0.3	-0.2	0.0	-0.1	-0.5	-0.1	0.1	0.5	0.0	-0.1	0.9
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.3	3.5	-0.4	-1.2	-1.1	-0.2	-1.2	0.5	-1.3	-1.2	-1.4	-1.6	0.7	1.9	-0.9	-1.0	-1.4	-0.5	-1.4
Medication: Gliclazide	0.6	0.7	2.3	0.7	-0.1	0.5	-1.3	-0.1	0.7	0.2	0.0	-0.8	-0.1	1.5	1.4	-0.5	-1.3	0.4	0.1	-1.3
Hearing aid user	0.6	0.6	1.3	0.5	1.0	0.8	-1.2	-0.0	-0.1	0.9	1.0	0.9	0.9	0.5	0.6	1.1	0.7	0.7	0.7	0.9
Medication: Lisinopril	0.6	0.7	2.1	-0.8	-0.7	-0.6	0.8	0.3	-1.4	-0.7	-0.8	-0.7	-0.6	0.9	-1.0	-0.9	-1.0	-0.7	-1.0	-1.1
Myopia	0.6	0.8	4.0	-1.0	0.1	-0.6	-1.9	-1.1	-1.3	-0.5	-0.6	0.5	-0.4	-0.3	2.0	0.2	0.3	-0.8	0.2	-0.1
Pain experienced in last month	0.6	1.0	3.3	-1.3	-1.5	-1.0	-0.7	-1.6	-0.7	-0.6	-1.2	-1.1	-0.9	-0.1	1.8	-1.4	0.4	-0.0	-0.1	0.4
Heart disease (siblings)	0.6	0.8	3.1	-0.9	-0.9	-1.2	0.3	-0.0	-0.5	-1.0	-0.7	-0.7	-1.1	-1.3	-0.0	-0.5	0.4	-0.5	-1.8	1.0
Alcohol drinker status: Previous	0.6	0.7	3.7	0.8	0.5	0.8	1.9	1.3	0.7	0.7	0.6	0.3	0.6	0.8	-1.3	0.2	0.0	0.8	0.3	0.1
Schizophrenia vs Biploar Disorder	0.5	0.6	3.4	-0.8	-0.3	-0.1	0.6	-1.4	-1.0	0.2	0.0	-0.5	-0.4	1.8	1.0	-0.6	0.0	-0.3	-0.2	-0.8
Crohns Disease (2017)	0.5	1.1	3.3	-0.5	-0.8	-1.2	-1.3	-0.9	-0.1	-0.9	-1.1	-0.9	-1.1	-1.7	1.8	-0.9	-1.0	-1.1	-1.0	-0.5
Irritable Bowel Disease (IBD)	0.5	1.1	3.1	-0.8	-0.7	-1.3	-0.7	-0.3	-0.8	-1.0	-1.3	-0.8	-1.2	-1.2	1.8	-0.9	-1.2	-1.2	-1.0	-0.9
Fasting Glucose	0.5	0.6	2.8	0.8	0.6	0.2	-0.9	0.1	1.1	-0.5	0.0	0.0	-0.1	1.4	0.6	0.6	-0.6	-1.2	0.2	-1.7
Primary Biliary Cirrhosis	0.5	0.7	5.9	-0.6	-0.5	-0.6	-0.1	-0.5	0.5	-0.6	-0.8	0.1	0.1	0.1	2.4	-0.4	1.4	-0.4	0.7	0.2
Medication for hormone replacement therapy	0.5	0.5	1.2	0.4	0.4	0.9	0.8	0.4	0.3	1.0	0.8	0.4	0.7	0.6	-0.7	0.5	0.6	1.1	1.1	1.0
Diabetes (mother)	0.5	0.6	3.0	0.7	0.9	0.6	0.6	0.2	1.0	0.4	0.1	1.0	0.6	0.1	1.7	0.8	0.9	-0.1	1.4	-0.1
Pack years adult smoking proportion	0.5	0.8	1.8	-0.8	-1.2	-1.0	-0.1	-0.5	-0.3	-1.1	-1.1	-1.3	-1.2	0.2	1.0	-1.1	-0.4	-0.7	-1.0	0.0
Maternal smoking around birth	0.5	0.7	2.7	-0.4	0.7	0.6	0.8	-0.2	-1.1	0.6	0.3	0.7	0.4	-0.4	0.1	1.0	1.5	0.4	1.6	1.2
Nervous feelings	0.5	0.9	4.9	1.2	-0.1	0.6	-0.2	-0.1	1.8	0.6	0.6	-1.0	-0.4	2.2	-0.3	-0.3	-1.2	0.4	-0.6	-1.0
Forced vital capacity (FVC)	0.5	2.0	9.1	-0.8	-1.1	-1.4	-1.4	-2.4	-0.4	-1.5	-1.6	-1.0	-1.7	-0.2	3.0	-0.8	-0.4	-1.7	-0.3	-0.8
Father’s age at death	0.5	0.6	1.9	0.9	1.2	0.3	0.3	-0.4	1.3	0.2	0.3	1.2	0.3	-0.7	0.7	1.4	0.9	-0.4	0.9	0.3
Depression (self-reported)	0.5	0.6	2.0	1.1	1.3	0.5	-0.5	0.2	1.0	0.4	0.8	1.4	0.7	0.5	-0.0	1.0	0.5	-0.1	0.3	0.0
Medication: Lansoprazole	0.5	0.6	2.2	-0.8	-0.6	-0.3	0.9	-0.8	-1.1	-0.4	-0.9	-0.6	-0.4	1.5	0.0	-0.8	-0.2	-0.6	-0.2	-1.2
Chronic bronchitis/emphysema (mother)	0.5	0.5	2.7	-1.3	-0.8	-0.5	-0.0	-1.1	-1.6	-0.6	-0.9	-0.6	-0.3	-0.6	0.4	-0.5	0.1	-0.2	0.3	0.2
Comparative body size at age 10	0.5	1.5	3.0	0.7	1.4	1.1	1.2	1.7	-0.2	1.1	1.1	1.5	1.6	1.2	-1.7	1.2	1.1	1.1	0.9	0.7
Number of full brothers	0.5	0.6	2.1	-0.2	0.7	0.5	0.7	0.4	-0.3	0.8	0.7	1.0	0.8	-0.8	-0.5	0.8	1.4	0.5	1.0	0.7
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.6	4.9	0.7	0.6	0.5	-1.0	0.9	0.6	0.5	1.1	0.4	0.7	-0.0	-2.2	0.5	0.1	0.4	0.1	0.4
Emphysema/chronic bronchitis	0.5	0.5	1.8	-0.7	-0.8	-0.8	-0.2	-1.0	-0.6	-0.6	-0.8	-0.5	-0.5	-0.0	1.0	-0.7	0.7	-0.2	-0.5	1.3
Medication: Blood pressure	0.5	0.8	1.6	0.9	1.1	1.2	-0.4	0.5	0.2	1.2	1.0	0.9	1.1	0.7	-1.2	1.1	0.6	1.0	0.6	-0.3
Comparative height size at age 10	0.5	3.0	6.4	-1.7	-1.4	-1.9	-1.1	-2.5	-1.2	-1.9	-2.1	-1.7	-2.5	0.0	1.5	-1.3	-0.9	-2.5	-1.0	-2.0
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	2.8	-0.3	-0.4	0.3	-0.1	0.4	-0.7	0.5	0.0	0.2	0.7	-0.8	-1.0	0.0	1.4	1.2	0.6	1.7
Supplements: Vitamin C	0.5	0.6	1.6	0.7	0.6	1.0	-1.3	-0.1	0.0	0.9	0.9	0.4	1.0	0.9	-1.1	0.4	0.4	1.1	0.8	0.5
Knee pain experienced in last month	0.5	0.7	2.9	0.9	1.2	0.6	1.1	1.3	0.0	0.5	0.5	0.9	0.4	1.1	-1.7	1.0	-0.1	-0.0	-0.1	0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.6	2.2	0.9	0.8	1.0	0.8	0.6	0.2	1.0	0.6	0.5	0.7	1.5	-0.4	0.7	0.1	0.6	0.9	-0.5
Wears glasses or contact lenses	0.5	0.6	2.9	0.5	0.2	0.3	-0.4	0.3	0.8	0.3	0.5	0.6	1.0	-1.2	-0.7	0.4	1.0	0.8	0.4	1.7
High cholesterol (Self-reported)	0.5	0.9	3.3	-1.1	-1.0	-1.0	-1.3	-0.6	-1.8	-0.6	-0.7	-0.9	-1.0	0.1	0.1	-0.7	-0.8	-0.5	-1.6	0.0
Vascular/heart problems diagnosed by doctor	0.5	1.2	4.6	-0.4	-0.5	-1.3	0.2	-1.0	0.4	-1.7	-1.6	-0.2	-1.1	0.6	2.2	-0.7	-0.4	-2.0	-0.1	-1.2
Coronary Artery Disease (CAD)	0.4	0.5	2.0	0.2	0.0	0.5	0.2	1.4	-0.4	0.5	0.6	0.0	0.5	-0.4	-1.4	0.4	0.0	1.2	-0.0	1.3
Neuroticism (2016)	0.4	0.5	1.2	-0.1	-0.7	-0.9	0.7	0.3	0.3	-1.1	-1.0	-0.6	-0.5	0.6	-0.1	-0.6	-1.1	-0.9	-1.0	-0.8
Cardiovascular Disease	0.4	1.2	3.8	-0.7	-1.2	-0.5	-0.6	0.5	-1.2	-0.4	-0.3	-1.8	-0.9	0.1	-1.6	-1.2	-2.0	0.1	-1.8	-0.9
Lung FVC	0.4	2.2	4.4	-0.8	-1.7	-1.9	-1.3	-1.2	-0.6	-2.0	-1.6	-1.4	-1.7	-0.4	1.6	-1.6	-1.8	-1.6	-2.1	-0.6
Ever had hysterectomy (womb removed)	0.4	0.5	3.7	-0.4	-0.4	0.2	0.2	0.3	-1.3	0.4	0.5	-0.5	0.1	1.9	-0.7	-0.6	-0.2	0.8	-0.5	0.1
Systolic blood pressure, automated reading	0.4	1.1	4.1	0.4	1.0	0.9	-0.1	1.0	-0.5	1.1	1.4	1.0	1.1	-2.0	-1.3	1.0	0.5	1.1	-0.1	1.2
Medication: Co-codamol	0.4	0.5	1.3	-0.5	-0.2	-0.7	0.8	0.4	-0.7	-0.7	-0.7	-0.2	-0.9	0.6	0.7	-0.5	-0.9	-1.1	-1.0	-0.5
Severe depression (siblings)	0.4	0.5	1.2	0.5	0.8	0.6	0.8	1.1	0.6	0.6	0.6	0.8	0.8	0.1	-0.3	0.9	0.6	0.3	1.1	0.6
Townsend deprivation index at recruitment	0.4	0.6	3.2	-0.2	-0.4	-0.2	0.8	0.4	-0.6	-0.4	-0.1	-0.8	-0.6	0.8	-0.6	-0.5	-1.8	-0.5	-0.6	-1.4
Current tobacco smoking	0.4	0.6	2.5	-0.2	-0.7	-0.7	0.6	-0.7	-0.0	-0.6	-0.5	-0.9	-1.2	1.6	0.2	-0.6	-0.7	-0.8	-0.6	-0.8
Bilateral oophorectomy (both ovaries removed)	0.4	0.5	3.2	0.5	0.0	0.4	0.7	0.5	0.2	0.4	0.5	-0.3	0.3	1.8	-0.9	-0.3	-1.0	0.3	0.5	-1.0
Tinnitus: Yes, but not now, but have in the past	0.4	0.4	2.6	-0.4	-0.2	0.2	0.9	-0.5	0.0	0.5	0.4	0.0	0.2	1.6	0.4	0.2	1.1	0.5	0.8	0.3
Serious illness, injury or assault to yourself	0.4	0.5	1.5	0.7	1.0	0.6	-0.3	-0.5	1.1	0.3	0.6	1.0	0.8	0.7	1.0	0.7	0.3	-0.1	1.2	-0.1
High blood pressure (mother)	0.4	0.6	3.2	0.6	0.9	0.4	-1.5	-0.2	0.5	0.4	0.5	1.1	0.4	-1.8	0.3	0.9	0.4	-0.2	0.7	0.2
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.7	3.0	0.6	0.6	0.2	1.7	1.2	0.6	0.1	0.5	0.7	0.5	-0.7	-1.4	0.4	0.2	0.4	-0.8	1.1
Diabetes (self-reported)	0.4	0.6	1.5	-0.3	-0.7	-0.6	-0.7	0.5	-0.1	-0.8	-1.2	-0.7	-0.7	-0.0	0.9	-0.9	-0.8	-0.8	-0.4	-1.2
Number of live births	0.4	0.6	2.4	-0.9	-0.6	0.4	0.5	-0.6	-1.3	0.4	-0.1	-0.5	0.2	0.5	1.1	0.0	1.1	0.8	1.6	0.7
Noisy workplace	0.4	0.5	1.2	-0.6	-0.6	-0.5	-0.9	-1.0	-0.3	-0.3	-0.1	-0.7	-0.6	0.8	1.1	-1.0	-0.9	-0.4	-0.9	-0.2
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.5	2.5	0.2	0.8	-0.4	-0.1	0.2	0.2	-0.5	-0.1	1.0	-0.1	-1.6	0.6	1.0	0.2	-1.2	-0.1	0.5
Medication: Ventolin 100micrograms inhaler	0.4	0.5	2.4	-0.8	-0.6	-0.7	-0.5	-1.1	-0.9	-0.5	-0.4	-0.6	-0.4	1.6	0.4	-0.5	-0.1	-0.3	-0.6	0.3
Leg fat percentage (right)	0.4	1.3	4.8	-0.5	0.9	0.8	-1.9	-1.1	-1.1	1.0	0.7	0.9	1.1	1.4	2.2	0.6	1.4	0.8	1.3	0.2
Overall health rating	0.4	0.9	2.6	1.0	1.2	1.0	1.1	1.4	0.5	0.8	1.1	0.7	0.8	0.9	-1.6	0.8	-0.5	0.7	-0.2	0.2
Arm fat percentage (left)	0.4	1.7	3.2	-0.1	1.5	1.5	-0.4	0.1	-1.3	1.7	1.3	1.6	1.8	1.0	1.2	1.2	1.6	1.6	1.5	0.9
Loneliness, isolation	0.4	0.6	1.1	-0.4	-0.8	-0.8	0.1	-0.8	-0.4	-1.0	-1.1	-0.9	-1.0	0.5	0.6	-0.9	-0.3	-0.8	-1.1	-0.2
Long-standing illness, disability or infirmity	0.4	0.7	1.7	-0.5	-1.0	-0.5	-0.8	-0.0	-0.6	-0.4	-0.7	-1.2	-0.8	1.1	0.3	-1.3	-1.2	0.0	-1.3	-0.6
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.5	1.4	-0.9	-1.2	-0.9	-0.1	-0.1	-0.7	-0.7	-0.7	-0.9	-0.6	-0.6	0.5	-1.0	0.1	0.1	-0.6	0.6
Friendships satisfaction	0.4	0.5	2.5	0.6	0.3	0.4	1.0	1.6	0.8	0.3	0.3	-0.0	0.4	0.5	-1.4	0.1	0.1	0.8	-0.2	0.5
Eye problems/disorders: Cataract	0.4	0.4	1.5	0.6	0.3	0.6	0.9	1.2	0.6	0.5	0.4	0.3	0.3	0.8	-1.2	0.3	-0.0	0.6	0.1	0.8
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	3.9	-0.1	0.1	0.8	0.1	-0.8	-0.8	0.9	0.5	-0.3	0.5	2.0	0.4	-0.6	0.0	1.2	0.2	-0.5
Medication for cholesterol	0.4	0.6	2.8	-0.3	0.2	-0.6	-0.3	-0.3	0.3	-0.7	-0.9	0.8	0.0	-1.7	1.4	0.2	1.1	-0.6	0.4	0.4
Smoking status: Current	0.4	0.7	3.9	-0.2	-0.7	-0.5	0.7	-0.6	-0.1	-0.4	-0.4	-1.0	-1.1	2.0	-0.1	-0.6	-0.9	-0.6	-0.6	-1.1
Miserableness	0.4	0.7	2.7	1.3	1.0	0.7	1.0	0.8	1.0	0.4	0.5	0.3	0.5	1.0	-1.7	0.8	-0.4	0.2	-0.4	-0.2
Financial situation satisfaction	0.4	0.5	1.7	0.1	0.8	-0.2	-0.4	0.4	-0.8	-0.4	-0.3	0.6	-0.2	-0.4	-1.2	0.4	-1.3	-1.1	-0.5	-1.2
Medication: Blood pressure	0.4	0.8	2.1	0.8	0.8	1.3	0.0	0.7	-0.1	1.4	1.5	0.2	0.9	0.8	-1.0	0.7	-0.4	1.4	0.3	0.7
Medication: Bendroflumethiazide	0.4	0.7	5.1	0.4	0.0	0.9	-0.3	-0.0	0.2	1.1	1.0	-0.4	0.5	2.3	-0.4	0.0	-0.4	1.5	0.1	0.2
Illnesses of father: High blood pressure	0.4	0.5	3.6	-0.1	-0.5	-0.2	0.1	-0.2	-0.0	-0.2	-0.2	-0.8	-0.5	1.3	-0.0	-0.7	-0.9	-0.5	0.0	-1.9
Age started oral contraceptive pill	0.4	0.5	3.0	0.8	0.1	0.8	0.5	0.5	0.8	0.7	0.8	-0.2	0.7	1.7	-0.2	-0.0	-0.4	1.0	0.2	0.2
Deep venous thrombosis (DVT) (self-reported)	0.4	0.6	2.1	-1.5	-1.1	-0.7	-0.1	-0.3	-1.3	-0.7	-0.6	-1.1	-0.5	-0.2	0.1	-1.0	-0.5	-0.5	-0.3	-0.4
Neuroticism (Nagel 2018)	0.3	0.8	1.6	1.1	1.3	1.0	0.5	1.1	0.3	1.2	1.2	0.9	0.6	0.5	-1.2	0.7	-0.2	1.0	-0.5	0.8
Alzheimer’s Disease (including proxy)	0.3	0.4	1.7	-0.4	0.3	-0.7	-0.4	-0.7	-1.0	-0.8	-0.4	0.5	-0.5	-0.3	0.7	-0.4	-0.6	-1.3	-0.4	-0.6
Ovarian Cancer	0.3	0.4	1.8	-0.9	-0.6	-0.4	-0.5	-1.0	-0.3	-0.3	-0.7	-0.3	-0.1	1.3	1.1	-0.7	0.5	-0.1	0.3	-0.6
Blood Eosinophil Count	0.3	2.0	4.7	-1.4	-1.1	-2.0	-1.1	-0.7	-1.1	-2.2	-2.1	-0.9	-1.7	-0.3	1.7	-0.9	-0.7	-2.2	-1.2	-0.6
Blood White Count	0.3	2.4	9.4	-1.1	-0.5	-1.8	-1.5	-1.7	-0.8	-1.8	-1.7	-0.4	-2.0	-1.5	3.1	-0.2	-0.1	-2.3	-1.4	-0.5
Heel T-Score	0.3	2.0	6.7	0.1	1.1	1.4	-0.5	-0.2	-0.6	2.2	1.7	1.5	2.1	0.2	-0.3	0.8	2.1	2.6	0.6	2.0
Allergy or Eczema	0.3	0.7	2.7	-1.2	-0.1	-0.7	-0.5	-0.7	-1.6	-0.7	-0.8	0.4	0.1	-1.6	0.9	0.0	1.1	-0.4	-0.0	1.0
Type 2 Diabetes (T2D) (2018)	0.3	0.6	2.8	0.5	-0.1	0.2	0.6	1.4	0.5	-0.3	-0.6	-0.1	-0.3	1.5	0.8	-0.4	-0.9	-0.6	0.2	-1.7
Chronotype (morning person)	0.3	0.8	1.4	0.7	1.0	1.1	-1.2	-0.3	-0.2	1.1	0.7	0.9	1.1	1.0	0.9	1.1	0.4	1.2	1.0	0.2
Hand grip strength (left)	0.3	0.8	4.2	-0.3	0.2	0.5	-0.4	-0.7	-0.6	0.7	0.4	0.3	0.7	-0.1	2.0	0.3	1.6	1.2	0.6	1.3
Relative age of first facial hair	0.3	0.7	2.0	-0.8	-0.8	-0.5	-0.6	-0.7	-1.3	-0.4	-0.4	-1.1	-0.5	0.4	0.7	-1.0	-1.4	-0.6	-0.7	-1.2
Medication: Metformin	0.3	0.4	3.4	-0.3	0.1	-0.1	-1.0	-0.7	-0.7	-0.1	-0.4	0.4	0.1	0.2	1.9	-0.1	0.4	-0.2	0.3	-0.2
Trunk fat percentage	0.3	1.2	4.8	-0.7	0.6	0.8	-1.1	-0.9	-1.6	1.1	0.6	0.5	0.9	2.2	1.8	0.3	1.0	1.1	1.0	-0.1
Hand grip strength (right)	0.3	0.8	4.7	-0.6	-0.1	-0.1	-1.4	-1.2	-0.8	0.2	-0.2	0.2	0.2	-1.2	2.2	0.0	1.3	0.6	0.0	1.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.4	1.8	0.7	0.9	0.2	1.4	1.1	0.3	-0.0	0.1	1.0	0.5	0.6	0.1	0.6	0.4	-0.3	-0.3	0.1
High blood pressure	0.3	0.9	4.9	0.1	0.2	1.0	-0.4	0.8	-0.7	1.4	1.4	-0.0	0.8	-0.5	-2.2	0.4	-0.1	1.7	-0.2	0.6
Supplements: Glucosamine	0.3	0.4	2.8	-0.2	-0.5	-0.3	-1.1	0.1	-0.5	-0.4	-0.5	-0.6	-0.5	-1.7	0.1	-0.4	-0.5	-0.4	-0.7	-0.3
Sitting height	0.3	2.2	9.0	-2.1	-0.8	-0.9	-1.8	-3.0	-2.2	-0.7	-1.1	-1.1	-1.2	0.5	2.7	-0.7	0.8	-1.1	0.5	-0.6
Trunk fat mass	0.3	1.2	5.4	-1.2	0.2	0.3	-1.1	-1.4	-2.1	0.5	0.0	0.1	0.3	1.9	2.3	0.0	0.8	0.3	0.7	-0.4
Had menopause	0.3	0.4	1.1	-0.6	-0.5	0.5	0.8	0.7	-1.1	0.6	0.4	-0.5	0.5	0.4	-0.8	-0.4	0.1	1.0	0.6	0.1
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.7	1.6	0.2	0.9	0.9	0.9	0.8	-0.7	1.3	0.8	0.9	0.9	1.0	-0.1	0.6	1.2	1.1	0.2	0.9
Financial difficulties in last 2 years	0.3	0.4	1.2	0.9	1.0	0.8	0.6	-0.2	0.3	0.5	0.9	0.3	0.3	1.1	0.2	0.8	-0.6	0.1	0.3	-0.5
Arm fat percentage (right)	0.3	1.3	2.6	-0.1	1.3	1.3	-0.5	0.1	-1.4	1.5	1.2	1.3	1.6	1.2	0.9	1.0	1.3	1.5	1.2	0.7
Trunk fat-free mass	0.3	1.5	4.6	-1.5	-0.6	-1.3	-0.6	-1.2	-2.0	-1.4	-1.5	-0.8	-1.4	-0.2	2.1	-0.5	-0.3	-1.8	-0.3	-0.8
Hip circumference	0.3	1.1	2.7	-0.4	1.3	0.9	-0.6	-0.5	-1.6	1.0	0.7	1.1	0.9	1.0	1.6	1.2	1.5	0.5	1.4	0.4
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.6	2.8	0.8	0.6	0.6	0.3	1.7	0.8	0.4	0.6	0.5	0.5	-0.6	-0.8	0.9	0.0	0.4	-0.2	1.2
Forced expiratory volume in 1-second (FEV1)	0.3	0.9	8.8	0.3	0.2	-0.0	-1.0	-1.6	0.5	-0.2	-0.3	0.4	-0.1	-0.0	3.0	0.4	0.7	-0.5	1.2	0.1
Asthma	0.3	0.6	1.9	0.1	-0.6	-0.3	0.8	1.4	-0.2	-0.3	0.1	-0.7	-0.1	1.4	-1.3	-0.8	-1.0	0.1	-1.3	0.2
Medication: Cholesterol lowering	0.3	0.4	4.7	-0.0	-0.4	0.1	-2.2	-0.5	-0.2	0.3	0.1	-0.4	0.1	-0.5	0.1	-0.1	-0.1	0.8	-0.5	0.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	1.1	9.3	0.1	0.1	-0.1	-1.1	-1.9	0.6	-0.3	-0.3	0.1	-0.3	-0.2	3.1	0.4	1.1	-0.6	1.4	0.1
Trunk predicted mass	0.3	1.5	4.2	-1.5	-0.6	-1.2	-0.6	-1.2	-2.0	-1.4	-1.5	-0.8	-1.4	-0.2	2.1	-0.5	-0.4	-1.7	-0.4	-0.8
Hair/balding pattern: Pattern 4	0.3	0.8	1.8	1.1	1.1	1.2	0.7	0.0	1.2	1.2	1.0	0.9	1.1	0.2	0.2	0.9	0.7	1.1	1.3	0.0
Medication: Paracetamol	0.3	0.4	1.6	1.1	1.2	0.8	0.6	0.2	0.7	0.6	0.7	0.9	0.4	0.1	0.0	1.0	-0.0	0.2	0.5	-0.1
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	4.4	0.3	0.4	-0.2	2.1	0.7	0.5	-0.4	-0.1	0.5	-0.2	0.0	0.4	0.2	-0.4	-1.1	0.4	-0.4
Body fat percentage	0.3	1.2	4.4	-0.8	0.6	0.7	-1.3	-1.1	-1.6	0.9	0.5	0.6	0.9	1.9	2.1	0.4	1.1	0.8	0.9	0.0
Arm fat-free mass (right)	0.3	1.5	5.6	-1.5	-0.6	-1.1	-0.2	-1.1	-2.2	-1.3	-1.4	-0.7	-1.1	0.3	2.4	-0.5	-0.4	-1.6	-0.3	-0.8
Mouth/teeth dental problems: Loose teeth	0.3	0.3	3.7	0.3	0.0	0.3	0.3	0.7	0.5	0.1	0.3	-0.3	0.3	0.1	-1.9	0.0	-0.6	0.4	-0.2	0.2
Mean time to correctly identify matches	0.3	0.5	3.9	0.3	-0.0	0.2	-0.6	0.7	0.1	0.2	0.5	-0.5	0.1	1.5	-2.0	0.0	-0.4	0.4	-0.7	0.5
Whole body fat mass	0.3	1.1	5.3	-1.1	0.4	0.3	-1.1	-1.2	-2.0	0.4	0.1	0.3	0.5	2.0	2.3	0.1	0.8	0.2	0.8	-0.4
Leg fat mass (right)	0.3	1.0	5.1	-0.8	0.8	0.4	-1.0	-1.1	-1.6	0.5	0.2	0.8	0.7	1.1	2.3	0.6	1.2	0.2	1.0	0.1
Arm predicted mass (right)	0.3	1.4	6.7	-1.5	-0.5	-1.1	-0.5	-1.2	-2.1	-1.2	-1.4	-0.6	-1.0	0.1	2.6	-0.4	-0.1	-1.5	-0.2	-0.5
Hypertension (Self-reported)	0.3	0.8	4.4	0.0	0.1	1.0	-0.6	0.7	-0.8	1.3	1.3	-0.3	0.6	-0.3	-2.1	0.2	-0.5	1.5	-0.2	0.1
Mood swings	0.3	0.6	1.5	0.3	0.9	0.5	0.8	0.5	0.1	0.6	0.5	1.0	0.7	-0.7	-0.6	1.0	1.2	0.6	0.7	1.1
Asthma (self-reported)	0.3	0.6	2.7	0.0	-0.6	-0.3	0.8	1.3	-0.3	-0.3	-0.1	-0.7	-0.1	1.6	-1.1	-0.8	-0.9	0.0	-1.3	0.1
Osteoarthritis (self-reported)	0.3	0.3	2.4	0.2	-0.4	0.1	-0.3	0.9	0.2	0.0	-0.3	-0.5	-0.1	-1.5	-0.3	-0.1	0.6	0.5	-0.2	1.1
Guilty feelings	0.3	0.5	1.2	-0.4	-0.0	-0.4	-0.8	-0.3	-1.0	-0.5	-0.4	-0.3	-0.6	0.7	-0.4	-0.5	-1.0	-0.8	-1.1	-0.9
Leg fat percentage (left)	0.3	1.1	4.6	-0.7	0.5	0.5	-1.7	-1.2	-1.4	0.7	0.5	0.4	0.9	1.5	2.1	0.3	1.1	0.8	1.0	0.3
Arm fat-free mass (left)	0.3	1.3	4.8	-1.3	-0.6	-1.1	-0.6	-1.1	-2.0	-1.2	-1.4	-0.8	-1.1	0.3	2.2	-0.4	-0.5	-1.5	-0.4	-0.8
Ever depressed for a whole week	0.3	0.3	2.0	-0.3	0.6	-0.3	0.9	0.2	-0.2	-0.3	0.1	0.4	-0.1	-1.4	-0.7	0.6	0.5	-0.6	0.3	0.4
Unable to work because of sickness or disability	0.3	0.4	1.2	-0.4	-0.8	-0.7	-0.4	-0.4	-0.3	-0.7	-0.5	-0.8	-0.7	-1.1	0.5	-0.5	0.1	-0.2	-1.0	0.9
Commuting to job workplace: Cycle	0.3	0.3	1.3	-0.0	-0.2	-0.6	-1.1	0.2	0.1	-0.6	-0.7	0.0	-0.4	-0.7	0.2	-0.2	-0.8	-0.9	-0.6	-0.7
Depressed Affect (Nagel 2018)	0.2	0.5	1.7	0.7	0.9	0.5	0.9	0.8	0.1	0.4	0.5	0.8	0.6	-0.4	-1.0	0.9	0.6	0.5	0.0	1.3
Schizophrenia (2018)	0.2	0.4	1.4	-0.5	0.4	0.5	0.5	-1.2	-0.4	0.8	0.8	0.2	0.3	0.3	-0.0	0.4	1.1	0.7	0.6	0.1
Alzheimer’s Disease (in mother)	0.2	0.3	1.1	0.1	1.0	-0.1	0.3	-0.4	-0.4	-0.0	0.2	1.0	0.1	-0.0	0.7	0.8	0.3	-0.9	0.6	0.1
Reaction Time	0.2	0.4	3.2	0.2	0.1	0.0	-0.4	0.3	-0.0	0.1	0.5	-0.4	-0.3	1.3	-1.8	0.1	-0.7	-0.1	-0.9	0.2
Body Mass Index (BMI) (2010)	0.2	0.3	3.8	-0.2	0.2	0.2	-0.5	-0.3	-0.6	0.4	0.4	-0.1	-0.1	1.9	-0.5	-0.4	-0.2	0.3	-0.1	-0.5
HbA1C	0.2	0.2	1.0	0.4	-0.2	0.1	-0.8	-0.6	1.0	0.1	0.2	-0.2	0.3	0.4	0.6	-0.4	0.5	0.5	-0.1	0.2
Schizophrenia (2014)	0.2	0.5	2.0	-0.4	0.3	0.7	0.6	-1.4	-0.3	0.9	0.9	-0.0	0.2	1.2	0.2	0.2	0.8	0.9	0.5	-0.3
BMI	0.2	1.1	3.1	0.0	1.5	0.8	0.4	0.2	-0.9	0.8	0.4	1.7	1.3	0.1	1.8	1.3	1.6	0.4	1.3	0.2
Respiratory disease	0.2	0.5	2.1	-0.5	-0.3	-0.4	0.6	0.4	-1.3	-0.2	0.2	-0.6	-0.3	1.0	-1.1	-0.3	-0.6	0.1	-1.4	0.7
Number of treatments/medications taken	0.2	0.4	1.4	0.2	-0.3	0.3	-0.6	0.0	-0.6	0.5	0.1	-0.9	-0.2	1.2	-0.8	-0.3	-0.8	0.7	-0.7	-0.5
Sensitivity / hurt feelings	0.2	0.3	1.8	0.6	0.6	0.4	0.5	0.8	0.2	0.5	0.4	0.4	0.3	0.8	-1.3	0.2	0.1	0.4	-0.6	0.3
Hearing difficulty/problems: Yes	0.2	0.3	1.1	0.2	0.3	0.3	-1.0	-0.4	-0.3	0.3	-0.0	0.5	0.5	-0.2	1.1	0.3	0.8	0.5	0.6	0.8
Ever used hormone-replacement therapy (HRT)	0.2	0.3	1.1	-0.5	-1.1	-0.3	-0.0	0.0	-0.7	0.0	-0.4	-1.1	-0.4	0.0	-0.4	-0.7	-0.2	0.2	-0.4	-0.0
Impedance of leg (right)	0.2	1.0	3.3	0.1	-0.4	-0.0	-1.7	-1.8	1.6	0.0	-0.2	-0.2	-0.2	1.1	1.7	-0.5	0.8	-0.4	1.1	-1.2
Age when periods started (menarche)	0.2	0.6	2.9	-1.3	0.1	0.5	-0.5	-0.9	-1.7	0.7	0.6	-0.1	0.0	0.8	-0.4	0.2	0.9	0.8	1.0	0.3
Hayfever, allergic rhinitis or eczema	0.2	0.4	3.2	-0.2	0.1	-0.4	0.1	0.3	-0.5	-0.5	-0.6	0.5	0.3	-1.8	-0.1	0.1	0.6	-0.1	-0.2	0.9
Body mass index (BMI)	0.2	0.8	1.7	0.0	1.2	1.0	-0.1	0.6	-1.2	1.0	0.9	1.2	1.3	0.6	0.6	1.1	0.8	1.0	0.8	0.8
Impedance of leg (left)	0.2	1.0	3.1	-0.2	-1.1	-0.5	-1.3	-1.8	1.5	-0.5	-0.6	-1.0	-0.7	1.0	1.6	-1.0	0.3	-0.6	0.5	-1.2
Past tobacco smoking	0.2	0.4	2.5	0.4	0.7	-0.2	0.1	0.5	0.5	-0.6	-0.3	1.1	-0.1	-0.3	0.5	0.9	0.2	-1.6	0.5	-0.1
Allergy	0.2	0.4	1.4	0.7	0.3	0.6	-0.0	-0.4	1.0	0.6	0.4	0.1	-0.0	1.0	0.5	0.4	-0.2	0.2	0.8	-1.2
Weight	0.2	0.7	3.9	-1.1	0.1	-0.2	-0.7	-1.0	-2.0	-0.2	-0.5	-0.0	-0.1	0.9	2.0	0.1	0.4	-0.5	0.4	-0.4
Impedance of arm (left)	0.2	0.7	2.5	0.2	0.4	1.0	-0.2	-0.5	0.9	1.2	0.9	0.6	0.8	0.9	0.2	0.4	1.4	1.1	1.6	0.0
Arm fat mass (right)	0.2	0.8	2.0	-0.3	0.9	0.9	-0.3	-0.1	-1.4	1.0	0.7	0.8	1.1	1.3	1.2	0.7	0.9	0.9	0.9	0.3
Length of working week for main job	0.2	0.2	0.8	-0.2	-0.1	-0.4	0.2	0.1	0.1	-0.5	-0.6	0.4	-0.1	-0.2	0.7	-0.0	0.2	-0.9	-0.1	-0.7
Exposure to tobacco smoke at home	0.2	0.2	0.6	0.2	0.8	0.3	0.6	0.4	-0.5	0.1	0.4	0.6	0.5	0.4	-0.4	0.7	0.0	0.0	0.1	0.4
Birth weight of first child	0.2	0.4	3.9	-0.6	0.3	-0.0	0.4	-0.2	-2.0	-0.0	-0.3	0.1	0.0	1.0	0.9	0.3	-0.3	-0.3	0.0	-0.8
Wheeze or whistling in the chest in last year	0.2	0.4	2.4	-0.6	0.3	-0.4	0.8	-0.1	-1.2	-0.2	-0.1	-0.0	-0.5	1.6	-0.4	-0.0	-0.4	-0.3	-1.0	-0.1
Neck or shoulder pain in last month	0.2	0.3	2.3	-0.3	-0.1	-0.6	0.4	0.1	-0.3	-0.6	-0.3	0.1	-0.2	-1.5	-0.1	0.2	0.4	-0.6	-0.5	0.5
Chest pain or discomfort	0.2	0.3	1.2	0.0	-0.6	-0.1	-0.1	1.1	-0.1	0.0	0.1	-0.6	-0.1	-0.5	-0.9	-0.6	-0.8	0.5	-0.7	0.5
Had major operations	0.2	0.2	0.8	-0.1	-0.3	-0.2	0.7	0.1	-0.0	-0.4	-0.5	0.3	0.2	-0.4	0.6	0.1	0.9	-0.2	0.4	0.6
Age at last live birth	0.2	0.3	1.1	0.7	-0.0	0.2	0.1	-0.1	1.0	0.1	0.1	-0.2	-0.4	0.6	0.9	-0.1	-0.7	-0.2	0.2	-0.9
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.3	3.1	0.2	-0.1	0.1	-1.7	-0.8	0.2	0.0	0.2	-0.2	0.2	0.4	0.7	0.1	0.0	0.4	-0.0	0.4
Smoking status: Previous	0.2	0.4	1.3	-0.6	-0.7	-0.1	-0.4	-0.4	-0.8	0.2	0.0	-0.7	0.1	-0.9	-0.1	-0.8	-0.0	1.1	-0.8	0.6
Whole body fat-free mass	0.2	0.9	4.6	-1.3	-0.2	-0.8	-0.3	-0.8	-2.1	-0.9	-1.0	-0.4	-0.8	0.1	1.9	-0.1	-0.1	-1.2	-0.1	-0.4
Diabetes diagnosed by doctor	0.2	0.4	1.0	-0.3	-0.6	-0.5	-0.2	0.4	-0.2	-0.7	-1.0	-0.5	-0.6	0.3	0.8	-0.7	-0.6	-0.7	-0.2	-0.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.3	2.2	0.0	0.3	-0.0	-0.9	-1.1	-0.5	-0.0	-0.2	0.4	-0.4	0.2	1.5	0.3	-0.4	-0.6	0.4	-0.6
Whole body water mass	0.2	0.9	4.5	-1.2	-0.2	-0.8	-0.1	-0.8	-2.1	-0.9	-1.0	-0.4	-0.8	0.1	1.8	-0.1	-0.2	-1.2	-0.1	-0.5
Arm fat mass (left)	0.2	0.9	1.7	-0.2	1.1	1.0	-0.3	0.1	-1.3	1.1	0.8	1.1	1.2	1.1	1.3	0.9	1.1	0.9	1.1	0.5
Number of self-reported non-cancer illnesses	0.2	0.4	2.1	-0.3	-0.4	0.0	0.3	1.2	-1.0	0.1	-0.1	-0.7	-0.3	0.6	-1.4	-0.2	-0.6	0.3	-0.8	0.4
Ever taken oral contraceptive pill	0.2	0.2	1.0	0.6	0.3	0.2	-0.6	0.4	1.0	0.0	-0.2	0.4	0.2	-0.8	0.2	0.1	0.3	0.1	0.3	-0.1
Mother’s age at death	0.2	0.3	1.0	0.4	0.4	0.4	0.5	0.1	-0.4	0.7	0.7	-0.1	-0.1	1.0	-0.7	0.6	-0.0	0.6	-1.0	0.2
Ever smoked	0.2	0.4	2.4	0.1	-0.5	0.4	0.2	-0.2	-0.1	0.9	0.8	-0.9	0.1	0.9	-0.9	-0.5	-0.4	1.5	-0.4	0.1
Basal metabolic rate	0.2	0.9	4.4	-1.2	-0.0	-0.6	-0.3	-0.9	-2.1	-0.7	-0.9	-0.2	-0.6	0.4	2.0	-0.0	0.1	-1.1	0.1	-0.4
Ever had prostate specific antigen (PSA) test	0.2	0.2	0.9	-0.2	0.2	0.3	-0.6	-0.0	-0.0	0.3	0.2	0.3	0.4	-1.0	-0.7	0.3	0.4	0.4	0.4	0.6
Diastolic blood pressure, automated reading	0.2	0.6	2.3	0.7	0.5	0.4	0.2	1.3	-0.1	0.4	0.9	0.5	0.7	-1.4	-1.5	0.4	-0.6	0.5	-1.0	0.4
Leg fat mass (left)	0.2	1.0	5.2	-1.0	0.6	0.3	-0.9	-1.1	-1.8	0.4	0.1	0.6	0.6	1.1	2.3	0.5	1.1	0.2	1.0	0.1
Arm predicted mass (left)	0.2	0.9	3.5	-1.1	-0.4	-0.9	-0.2	-0.8	-1.7	-1.1	-1.1	-0.7	-0.9	0.3	1.9	-0.3	-0.4	-1.3	-0.2	-0.6
Bipolar Disorder (2018)	0.1	0.2	1.5	0.1	-0.4	0.2	0.1	0.4	-0.0	0.2	0.1	-0.3	0.0	0.3	-1.2	-0.2	-0.1	0.6	0.4	0.0
Bipolar Disorder or Schizophrenia	0.1	0.3	0.9	-0.3	0.0	0.6	0.6	-0.6	-0.3	0.7	0.7	-0.1	0.3	0.4	-0.8	0.2	0.8	0.9	0.7	0.0
Worry (Nagel 2018)	0.1	0.2	1.0	0.2	0.5	0.5	-0.7	-0.3	-0.2	0.6	0.6	0.1	0.0	1.0	-0.3	-0.1	-0.5	0.5	-0.3	-0.3
Breast Cancer	0.1	0.2	1.0	0.6	-0.1	0.5	-0.2	0.4	0.8	0.5	0.2	-0.3	0.6	0.6	-0.1	-0.5	-0.0	1.0	-0.1	0.1
Crohns Disease (2012)	0.1	0.2	0.5	-0.3	-0.4	-0.6	-0.2	0.3	-0.0	-0.3	-0.3	-0.4	-0.2	-0.7	0.4	-0.7	-0.7	-0.2	-0.6	-0.1
Triglycerides	0.1	0.2	1.0	0.1	0.2	-0.0	-0.2	-0.8	-0.0	-0.1	0.0	0.5	-0.0	-0.5	0.8	0.5	1.0	-0.4	0.4	0.2
Blood Platelet Count	0.1	1.0	7.1	1.1	0.2	0.9	-2.7	0.7	0.6	0.8	0.6	-0.7	0.6	0.1	0.2	-0.5	-1.6	1.4	-0.5	-0.8
Leg fat-free mass (left)	0.1	0.6	4.7	-1.0	0.4	-0.1	0.0	-0.5	-2.2	-0.3	-0.4	0.2	-0.1	0.4	1.5	0.4	0.3	-0.6	0.4	-0.1
Qualifications: CSEs or equivalent	0.1	0.1	0.6	0.1	0.3	0.1	0.1	0.2	-0.4	-0.2	-0.2	0.1	-0.0	0.4	-0.5	0.3	-0.8	-0.5	0.5	-0.6
Medication: Atenolol	0.1	0.1	0.6	0.2	0.3	-0.1	0.8	0.1	0.2	-0.4	-0.2	0.1	-0.1	-0.0	0.3	0.5	0.4	-0.4	0.1	0.1
Leg predicted mass (left)	0.1	0.6	4.5	-1.0	0.3	-0.2	0.1	-0.5	-2.1	-0.3	-0.5	0.2	-0.2	0.4	1.5	0.3	0.2	-0.7	0.3	-0.1
Waist circumference	0.1	0.3	1.6	0.0	0.8	0.1	-0.5	0.0	-0.5	0.0	-0.1	0.5	0.1	1.0	1.3	0.4	-0.1	-0.6	0.3	-0.9
Ever unenthusiastic/disinterested for a whole week	0.1	0.2	1.2	-0.0	0.6	-0.2	0.6	0.4	-0.1	-0.1	0.4	0.3	-0.1	0.0	-1.1	0.5	0.1	-0.4	-0.3	0.3
Impedance of arm (right)	0.1	0.4	2.1	0.2	-0.2	0.6	-0.4	-0.7	1.0	0.7	0.5	-0.2	0.2	1.5	-0.1	-0.2	0.5	0.6	0.8	-0.8
Pulse wave reflection index	0.1	0.2	0.5	0.3	0.7	0.0	0.2	0.0	-0.5	0.0	0.3	0.6	0.1	0.3	0.7	0.5	-0.7	-0.3	-0.4	0.4
Age at first live birth	0.1	0.3	1.6	0.7	0.3	0.0	1.3	0.7	0.8	-0.0	-0.1	0.3	-0.2	-0.6	0.4	0.2	-0.3	-0.3	-0.1	-0.3
Leg fat-free mass (right)	0.1	0.6	5.0	-1.1	-0.0	-0.5	0.4	-0.3	-2.2	-0.6	-0.7	-0.2	-0.4	0.4	1.3	0.0	-0.1	-0.7	-0.0	-0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.1	0.2	0.9	-0.0	0.1	0.1	0.6	0.4	-0.1	0.0	0.2	-0.1	0.1	0.8	-0.7	0.1	0.2	0.3	-0.2	0.9
Leg predicted mass (right)	0.1	0.6	4.9	-1.1	-0.0	-0.5	0.3	-0.4	-2.2	-0.6	-0.7	-0.2	-0.4	0.4	1.3	-0.0	-0.1	-0.7	-0.0	-0.1
Impedance of whole body	0.1	0.6	2.2	-0.2	-0.6	0.0	-1.0	-1.5	1.2	0.2	-0.1	-0.4	-0.1	0.8	1.1	-0.5	0.9	0.1	1.0	-0.6
Hair Pigment	0.0	0.5	1.7	0.4	-0.2	-0.3	-0.8	0.5	0.5	-0.3	-0.3	0.1	0.2	0.4	-1.3	-0.9	-1.2	0.0	-1.1	-1.1
Tanning	0.0	0.3	0.8	-0.6	-0.9	0.1	0.1	-0.5	-0.7	0.4	0.0	-0.8	-0.2	0.4	0.5	-0.8	-0.1	0.7	0.3	0.3
Medication: Paracetamol	0.0	0.1	0.3	0.5	0.2	0.0	0.4	-0.2	0.6	-0.0	-0.0	-0.0	-0.3	-0.3	0.4	0.2	-0.4	-0.0	-0.1	0.1

Hub : Genes

DNMBP

Models

Trait associations