TWAS hub - DOCK10

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Cells EBV-transformed lymphocytes	0.3670	0.0760	1.2e-05	0.182	NA	0.204	NA	0.184	1.5e-06	NA	3.1e-07	NA	1.3e-06
2	NTR	Blood	0.0406	0.0134	4.8e-06	0.020	0.022	0.021	0.019	0.019	2.7e-07	6.4e-08	1.7e-07	6.6e-07	6.2e-07
3	YFS	Blood	0.1968	0.0295	0.0e+00	0.067	0.149	0.160	0.159	0.150	4.1e-21	2.1e-46	5.9e-50	1.7e-49	1.1e-46

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Noisy workplace	6.3	7.7	12.7	2.5	-3.6	-2.0
Frequency of unenthusiasm / disinterest in last 2 weeks	5.7	7.6	12.5	-0.5	-3.2	-3.5
Number of full brothers	5.4	6.8	14.1	-0.7	-3.8	-2.4
Average weekly beer plus cider intake	5.2	7.5	13.2	-0.1	-3.6	-3.0
Had menopause	4.9	6.1	8.0	1.8	2.7	2.8
Alcohol usually taken with meals	4.7	7.6	12.0	2.6	3.5	2.1
Back pain experienced in last month	4.7	6.8	11.2	0.3	-3.4	-3.0
Frequency of depressed mood in last 2 weeks	4.6	6.5	11.8	-1.0	-2.6	-3.4
Illness, injury, bereavement, stress in last 2 years	4.5	5.5	10.7	-0.1	2.4	3.3
Miserableness	4.5	7.9	13.0	2.0	-2.6	-3.6
Hypothyroidism (self reported)	4.3	9.8	15.3	-3.9	-2.2	-3.0
Pain type(s) experienced in last month: Hip pain	4.3	5.4	12.7	-0.2	-3.6	-1.9
Hair/balding pattern: Pattern 2	4.0	5.0	7.8	-1.5	-2.8	-2.2
Pack years adult smoking proportion	3.8	5.8	9.9	-2.6	-3.1	-0.8
Unable to work because of sickness or disability	3.7	4.8	9.6	0.2	-3.1	-2.2
Hair/balding pattern: Pattern 3	3.5	5.2	8.2	2.5	2.9	1.0
Pain experienced in last month	3.4	5.6	7.0	2.5	2.6	1.9
Smoking Status	3.2	7.8	16.6	0.3	-4.1	-2.6
Diabetes (father)	3.2	4.0	9.3	-3.1	-1.3	-1.0
Shortness of breath walking on level ground	3.2	3.8	5.7	0.2	-2.4	-2.4
Commuting to job workplace: Public transport	3.2	3.8	6.5	2.6	1.6	1.6
Irritability	3.2	5.5	8.4	-1.6	-2.9	-2.3
Townsend deprivation index at recruitment	3.1	4.3	7.1	1.5	-2.7	-1.9
Current tobacco smoking	3.1	5.1	11.0	0.3	-3.3	-2.1
Average weekly fortified wine intake	3.1	3.6	8.5	1.0	1.1	2.9
Age started oral contraceptive pill	3.1	3.9	5.1	1.2	2.3	2.2
Pack years of smoking	3.1	4.5	8.4	-2.2	-2.9	-0.7
Blood Platelet Count	3.0	34.8	68.9	-8.3	-3.5	-4.8
Blood White Count	3.0	22.3	41.3	-2.5	-4.4	-6.4
Depression (self-reported)	3.0	3.6	8.7	-0.4	-3.0	-1.4
Ever highly irritable/argumentative for 2 days	3.0	3.6	5.2	-0.8	-2.3	-2.2
Loud music exposure frequency	3.0	3.2	5.3	1.2	-1.7	-2.3
Qualifications: College or University degree	3.0	9.4	18.3	2.3	4.3	2.2
Hearing difficulty/problems: Yes	2.9	4.4	12.6	3.5	-0.5	0.7
Fed-up feelings	2.9	5.2	11.4	-0.4	-2.0	-3.4
Qualifications: O levels/GCSEs or equivalent	2.8	4.5	6.3	-1.1	2.5	2.4
Health satisfaction	2.8	3.7	6.6	0.2	-2.1	-2.6
Maternal smoking around birth	2.7	3.9	7.0	-1.1	-2.6	-1.9
Frequency of tenseness / restlessness in last 2 weeks	2.7	4.3	10.8	-1.1	-0.9	-3.3
Qualifications: A levels/AS levels or equivalent	2.7	6.0	12.6	0.0	3.5	2.3
Average weekly red wine intake	2.7	4.0	9.9	3.1	1.4	0.1
Qualifications: nursing, teaching	2.7	4.3	9.2	-0.5	1.8	3.0
Medication: Atorvastatin	2.6	3.2	9.2	-3.0	-0.3	-0.6
Qualifications: None of the above	2.5	5.4	9.1	1.2	-3.0	-2.4
Father’s age at death	2.5	3.3	4.4	-1.6	1.7	2.1
Leg pain on walking	2.5	3.2	5.2	0.2	-2.3	-2.1
Supplements: Vitamin C	2.5	2.9	7.9	-0.3	2.8	0.9
Hearing aid user	2.5	2.9	3.8	1.9	2.0	1.1
Average weekly spirits intake	2.4	2.9	5.9	-1.1	-2.4	-1.2
Ever unenthusiastic/disinterested for a whole week	2.4	2.9	6.9	-0.6	-2.6	-1.2
Age at first live birth	2.4	4.2	6.1	1.5	2.1	2.5
Age when periods started (menarche)	2.3	5.5	12.3	-1.7	-3.5	-1.2
Diverticular disease/diverticulitis (self-reported)	2.3	2.7	2.8	1.7	1.7	1.6
Length of working week for main job	2.3	2.5	3.9	-2.0	-1.9	0.2
Breastfed as a baby	2.3	2.9	5.5	-2.4	1.0	1.5
Age at last live birth	2.3	3.3	5.7	1.7	2.4	1.2
Smoking status: Current	2.3	3.7	7.8	0.9	-2.8	-1.6
Alcohol drinker status: Never	2.3	2.8	7.0	-2.6	0.7	-0.9
Seen a psychiatrist for nerves, anxiety, tension or depression	2.2	2.9	5.2	-0.4	-2.3	-1.8
Medication: Omeprazole	2.1	2.5	7.5	-2.7	-0.2	0.1
Commuting to job workplace: Car/motor vehicle	2.0	2.3	5.3	-1.1	-2.3	-0.5
Loneliness, isolation	2.0	2.8	5.2	0.3	-1.7	-2.3
Age at First Birth	1.9	2.8	8.2	-0.4	2.9	0.4
Hypothyroidism/myxoedema (self-reported)	1.9	3.8	4.8	-2.2	-1.4	-2.2
Qualifications: NVQ or HND or HNC or equivalent	1.9	2.3	4.0	0.6	-1.6	-2.0
Mood swings	1.9	3.5	5.4	0.5	-2.2	-2.3
Long-standing illness, disability or infirmity	1.9	2.9	4.8	-0.2	-2.0	-2.2
Medication: Gliclazide	1.9	2.1	2.8	-1.3	1.7	1.4
Medication: Omeprazole (e.g. Zanprol)	1.9	2.4	7.0	-2.6	0.1	-0.3
Basal cell carcinoma (self-reported)	1.9	2.3	2.4	1.6	1.5	1.5
Taking other prescription medications	1.8	2.8	5.9	-2.4	-0.6	-1.5
Had other major operations	1.8	2.2	4.6	0.1	-1.4	-2.1
Medication: Lansoprazole	1.8	2.1	4.4	0.6	-1.2	-2.1
Wheeze or whistling in the chest in last year	1.8	3.2	6.4	-1.0	-2.5	-1.5
Number of full sisters	1.8	2.2	4.8	-1.0	-2.2	0.9
Illnesses of father: High blood pressure	1.8	2.3	6.7	-2.6	-0.5	-0.1
Ever had prostate specific antigen (PSA) test	1.8	2.1	3.3	0.5	1.8	-1.6
Depressed Affect (Nagel 2018)	1.7	3.7	8.8	0.8	-1.3	-3.0
Suffer from ‘nerves’	1.7	2.6	5.1	-1.6	-0.4	-2.3
Financial situation satisfaction	1.7	2.1	2.8	0.9	-1.7	-1.6
Depression (Nagel 2018)	1.6	2.4	6.4	-0.4	-0.8	-2.5
Hand grip strength (left)	1.6	4.2	12.1	-3.5	0.2	-0.6
Hand grip strength (right)	1.6	4.4	10.9	-3.3	-0.7	-1.3
Qualifications: CSEs or equivalent	1.6	2.2	6.1	-0.3	-2.5	-0.5
Stomach or abdominal pain in last month	1.6	2.0	3.1	-1.8	-0.5	-1.7
Allergy	1.6	3.7	7.0	1.0	-1.8	-2.6
Pain all over the body in last month	1.6	1.8	3.3	-0.6	-1.3	1.8
Exposure to tobacco smoke outside home	1.6	2.2	4.4	1.3	-2.1	-0.7
Medication: Seretide 50 evohaler	1.6	1.8	2.6	-1.6	0.6	1.6
Knee pain experienced in last month	1.6	2.5	3.5	-1.9	-1.6	-1.2
Alzheimer’s Disease (in father)	1.5	1.7	3.9	2.0	0.8	0.6
Alzheimer’s Disease (including proxy)	1.5	2.1	5.8	2.4	-0.0	0.8
Number of incorrect matches in round	1.5	2.5	6.2	2.5	1.1	0.1
Hearing difficulty/problems with background noise	1.5	2.5	7.2	2.7	-0.3	0.3
Illnesses of mother	1.5	1.9	5.7	-2.4	0.2	0.2
Osteoarthritis (self-reported)	1.5	1.9	4.4	2.1	-1.1	-0.4
Bipolar Disorder (2018)	1.4	2.1	5.5	0.6	-0.8	-2.3
Neuroticism (2016)	1.4	2.0	3.4	-0.9	-1.8	-1.4
Bilateral oophorectomy (both ovaries removed)	1.4	1.6	2.1	-1.1	-1.5	-1.2
Serious illness, injury or assault to yourself	1.4	1.7	4.8	0.1	-0.3	-2.2
Forced expiratory volume in 1-second (FEV1)	1.4	4.7	8.5	-1.9	-1.4	-2.9
Mouth/teeth dental problems: Bleeding gums	1.4	1.7	3.7	-1.2	0.0	1.9
Medication for cholesterol	1.4	2.1	3.9	0.8	1.3	2.0
Chronic bronchitis/emphysema (father)	1.3	1.5	2.5	-0.6	-1.6	1.3
Past tobacco smoking	1.3	2.5	5.3	-0.6	2.3	1.3
Happiness	1.3	1.6	3.1	-0.0	-1.8	-1.3
Forced expiratory volume in 1-second (FEV1), predicted	1.3	2.8	6.0	-2.5	0.4	-1.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.3	1.5	2.9	-1.7	0.1	1.2
Alzheimer’s Disease (in mother)	1.2	1.4	2.0	1.4	-0.6	1.4
Fasting Glucose	1.2	1.4	3.6	-0.8	-1.9	0.3
Number of treatments/medications taken	1.2	2.2	3.7	-1.9	-0.6	-1.6
Vitamin and mineral supplements	1.2	1.7	3.6	0.7	-1.9	-1.0
Hayfever, allergic rhinitis or eczema	1.2	2.6	4.4	-0.5	1.8	2.1
Medication: Atenolol	1.2	1.5	1.9	-1.1	-1.4	-1.1
Illnesses of siblings	1.2	1.7	3.1	-1.8	1.1	0.9
Frequency of tiredness / lethargy in last 2 weeks	1.2	1.9	3.8	-1.4	-0.4	-1.9
Serious illness, injury or assault of a close relative in last 2 years	1.2	1.3	2.0	1.4	0.2	-1.4
Mouth/teeth dental problems: Dentures	1.2	2.0	6.0	0.2	-0.2	-2.5
Prospective memory result	1.2	1.5	2.5	1.2	-1.6	-0.8
Pulse wave Arterial Stiffness index	1.2	1.3	3.9	-0.2	0.4	-2.0
Tense / ‘highly strung’	1.2	1.9	3.7	-1.4	0.1	-1.9
Seen doctor (GP) for nerves, anxiety, tension or depression	1.2	1.9	4.0	-0.6	-2.0	-1.1
Overall health rating	1.2	2.7	4.6	-1.6	-2.2	-0.8
Ever had bowel cancer screening	1.2	1.4	2.4	0.5	1.6	1.3
Schizophrenia vs Biploar Disorder	1.1	1.5	3.6	0.6	-0.7	1.9
Lupus	1.1	1.6	4.8	0.2	-2.2	-0.3
Allergy or Eczema	1.1	2.9	4.5	-0.6	2.1	1.9
Cardiovascular Disease	1.1	3.5	8.7	-0.3	-1.3	-2.9
Forced vital capacity (FVC)	1.1	4.3	8.8	-1.4	-1.4	-3.0
Peak expiratory flow (PEF)	1.1	2.4	6.7	-0.7	0.2	-2.6
Pulse wave peak to peak time	1.1	1.3	3.8	0.1	0.1	1.9
Eye problems/disorders: None of the above	1.1	1.3	3.4	0.2	1.8	0.6
Ever had stillbirth, spontaneous miscarriage or termination	1.1	1.1	2.2	1.0	0.4	1.5
Eye problems/disorders: Cataract	1.1	1.3	2.5	-0.1	-1.6	-1.1
Medication: Paracetamol	1.1	1.8	3.8	1.9	-0.5	1.1
Ever smoked	1.1	1.9	4.6	0.5	-2.1	-0.9
Fractured/broken bones in last 5 years	1.1	1.4	1.9	-1.4	1.4	0.7
Commuting to job workplace: Cycle	1.1	1.3	2.0	1.3	0.4	-1.4
Myopia	1.1	1.6	4.4	-2.1	-0.6	0.1
Bipolar Disorder or Schizophrenia	1.0	2.5	5.0	-0.2	-1.6	-2.2
Primary Biliary Cirrhosis	1.0	1.4	2.6	1.6	1.2	-0.3
Rheumatoid Arthritis	1.0	1.3	1.5	-1.1	-1.2	-1.1
Relative age of first facial hair	1.0	2.0	3.3	-1.8	1.6	0.5
Ever used hormone-replacement therapy (HRT)	1.0	1.2	1.8	1.4	-1.3	-0.2
Angina	1.0	1.4	4.0	0.3	-2.0	-0.1
Medication: Levothyroxine sodium	1.0	1.7	3.5	-1.3	-0.0	-1.9
Financial difficulties in last 2 years	1.0	1.3	2.1	-0.0	-1.3	-1.4
Hayfever/allergic rhinitis (self-reported)	1.0	1.3	2.0	-0.5	1.4	1.3
Forced expiratory volume in 1-second (FEV1), Best measure	1.0	3.2	6.1	-1.3	-1.3	-2.5
Illnesses of father: None of the above (group 1)	1.0	1.2	3.0	1.7	0.7	-0.3
Average weekly champagne plus white wine intake	1.0	1.4	3.9	-0.3	2.0	0.4
Supplements: Fish oil (including cod liver oil)	1.0	1.3	3.6	-0.3	1.9	0.4
Medication: Bendroflumethiazide	1.0	1.5	2.4	-1.6	1.4	0.1
Diastolic blood pressure, automated reading	1.0	3.0	6.8	0.3	-1.5	-2.6
Intelligence (Savage-Jansen 2018)	0.9	2.8	3.8	1.4	1.9	1.7
Verbal and Numeric Reasoning (VNR)	0.9	2.2	2.5	1.4	1.6	1.6
Diabetes (self-reported)	0.9	1.4	4.0	-2.0	0.6	0.0
Lung cancer (father)	0.9	1.0	2.8	-0.0	-0.5	-1.7
Headache pain in last month	0.9	1.6	3.9	-2.0	-1.0	0.1
Medication for cholesterol, blood pressure or diabetes	0.9	1.5	2.5	1.6	1.2	0.7
Medication: Ibuprofen	0.9	1.1	2.2	1.0	0.4	1.5
Mean time to correctly identify matches	0.9	1.7	2.1	1.3	-1.5	1.1
Smoking status: Previous	0.9	1.4	2.1	-0.0	-1.4	-1.4
Diabetes diagnosed by doctor	0.9	1.5	4.2	-2.0	-0.1	-0.6
Number of operations (self-reported)	0.9	1.3	2.5	-1.0	-0.6	-1.6
Reaction Time	0.8	1.6	4.2	0.6	-2.0	-0.4
Bipolar Disorder (2011)	0.8	0.7	1.2	0.5	0.8	-1.1
Schizophrenia (2014)	0.8	1.8	3.6	0.3	-1.9	-1.3
Triglycerides	0.8	1.2	2.9	1.7	-0.9	0.3
Ulcerative Colitis	0.8	1.2	1.9	0.5	1.2	1.4
Asthma	0.8	1.5	4.1	-2.0	0.7	-0.2
Birth weight of first child	0.8	1.5	4.0	-0.5	-0.6	2.0
Glaucoma (self-reported)	0.8	0.9	1.5	0.1	-1.2	-1.1
Medication: Amlodipine	0.8	1.1	1.6	0.8	-1.1	-1.3
Comparative body size at age 10	0.8	2.1	6.1	2.5	-0.4	0.0
Worry too long after embarrassment	0.8	1.4	1.8	0.8	1.4	1.3
Reason for reducing amount of alcohol drunk: Health precaution	0.8	0.9	2.2	1.5	0.7	0.0
Mouth/teeth dental problems: Loose teeth	0.8	0.9	1.9	0.3	-0.8	-1.4
Emphysema/chronic bronchitis	0.8	0.9	2.0	0.3	0.8	1.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.8	1.0	1.4	-1.2	1.1	-0.4
Asthma (self-reported)	0.8	1.7	4.2	-2.0	0.9	0.0
Wears glasses or contact lenses	0.8	0.9	1.8	1.3	0.2	0.9
Ovarian Cancer	0.7	1.0	2.0	0.5	-1.4	0.8
Systolic Blood Pressure	0.7	3.3	8.9	0.1	-0.9	-3.0
Lung FVC	0.7	3.7	4.0	-1.8	-2.0	-2.0
Ever had hysterectomy (womb removed)	0.7	0.8	1.4	-1.2	-0.6	0.8
Diabetes (mother)	0.7	0.9	2.3	0.5	1.5	-0.5
Mouth/teeth dental problems	0.7	1.1	1.8	0.7	0.9	1.4
Fluid intelligence score	0.7	1.4	1.6	1.1	1.3	1.2
Neuroticism score	0.7	1.4	2.3	0.9	-1.1	-1.5
Alcohol intake versus 10 years previously	0.7	1.1	1.8	0.9	-0.8	-1.3
Exposure to tobacco smoke at home	0.7	0.8	1.3	-0.8	-0.7	1.1
Pulse wave reflection index	0.7	0.9	2.2	-0.2	0.7	-1.5
High blood pressure (siblings)	0.7	1.1	2.1	0.5	-1.0	-1.4
Neck or shoulder pain in last month	0.7	1.0	2.5	-0.8	-0.2	-1.6
Friendships satisfaction	0.7	0.9	2.1	0.6	-1.4	-0.3
Mouth/teeth dental problems: Mouth ulcers	0.7	1.1	2.2	-0.9	-1.5	-0.5
Mineral and other dietary supplements	0.7	1.0	2.9	0.2	-1.7	0.0
Medication: Blood pressure	0.7	1.3	3.7	-0.5	0.2	-1.9
Alcohol drinker status: Previous	0.7	0.8	2.2	-0.2	-1.5	0.2
Schizophrenia (2018)	0.6	1.2	1.7	-0.7	-1.3	-1.1
Major Depression (MDD)	0.6	0.7	1.3	-0.7	-1.2	-0.5
Prostate Cancer	0.6	0.9	2.1	-0.3	1.4	0.7
Mean Putamen Volume	0.6	0.7	1.2	0.0	1.1	0.9
BMI	0.6	3.4	7.8	1.5	-2.8	-0.1
Medication for hormone replacement therapy	0.6	0.7	0.8	-0.8	-0.8	-0.9
Medication: Metformin	0.6	0.8	1.5	-1.0	0.2	-1.2
Relative age voice broke	0.6	0.9	2.6	0.3	1.6	-0.1
Time employed in main current job	0.6	0.7	1.2	-0.5	-1.1	-0.8
Number of live births	0.6	0.9	1.6	-0.9	1.3	0.4
Pulse rate	0.6	1.0	1.5	-1.2	0.6	-1.1
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.7	1.6	1.3	0.2	0.7
Hair/balding pattern: Pattern 4	0.6	1.5	2.5	-1.0	1.6	1.0
Blood clot in the leg (DVT)	0.6	0.8	1.2	-0.9	1.1	0.5
Medication: Paracetamol	0.6	1.1	1.6	1.2	0.5	1.3
Medication: Ventolin 100micrograms inhaler	0.6	0.8	1.8	-1.4	-0.6	-0.3
Birth weight	0.6	1.4	4.0	-0.3	-2.0	0.1
Forced vital capacity (FVC), Best measure	0.6	2.4	4.9	-1.4	-0.6	-2.2
Number of children fathered	0.6	0.7	1.5	1.2	0.7	0.1
Angina (self-reported)	0.6	0.8	2.3	0.2	-1.5	0.3
Chest pain or discomfort	0.6	0.8	2.2	0.3	-0.4	1.5
Medication: Aspirin	0.6	0.7	1.8	-1.4	0.2	-0.5
Hypertension (Self-reported)	0.6	1.6	4.6	0.2	-0.6	-2.1
Illnesses of father: Heart disease	0.6	0.8	2.4	1.5	-0.0	0.4
Commuting to job workplace: Walk	0.6	0.6	0.7	0.8	0.8	0.7
Number of self-reported non-cancer illnesses	0.6	1.0	3.0	-1.7	0.0	-0.4
Deep venous thrombosis (DVT) (self-reported)	0.6	0.8	1.2	-1.0	1.1	0.5
Neuroticism (Nagel 2018)	0.5	1.2	3.4	0.1	-0.3	-1.8
Ulcerative Colitis (UC)	0.5	1.0	2.9	0.3	0.3	1.7
Coronary Artery Disease (CAD)	0.5	0.6	1.4	1.2	0.5	-0.6
HbA1C	0.5	0.5	0.9	-0.3	0.7	1.0
Supplements: Zinc	0.5	0.5	1.5	-1.2	0.2	0.0
Severe depression (siblings)	0.5	0.6	1.1	-0.6	-0.6	-1.0
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.1	2.5	-1.6	0.7	0.4
Multivitamins +/- minerals	0.5	0.7	1.3	-0.2	1.2	0.8
High blood pressure (mother)	0.5	0.7	1.2	-0.0	-1.1	-1.0
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.2	1.5	-1.2	0.8	1.2
Arm fat percentage (right)	0.5	2.0	4.5	1.1	-2.1	-0.4
Worrier / anxious feelings	0.5	0.9	2.3	1.5	0.4	0.6
Chronic bronchitis/emphysema (mother)	0.5	0.5	0.9	0.8	-0.3	-0.9
Heart disease (mother)	0.5	0.6	1.3	1.1	0.5	-0.6
Illnesses of siblings: Diabetes	0.5	0.7	1.8	0.2	0.4	1.3
Arm fat percentage (left)	0.5	2.1	5.1	1.1	-2.2	-0.2
Medication: Lisinopril	0.5	0.6	1.0	-0.7	-1.0	-0.6
Heart disease (siblings)	0.5	0.6	1.2	0.4	-0.7	-1.1
Crohns Disease (2017)	0.4	0.8	1.6	-0.2	-1.3	-0.9
LDL Cholesterol	0.4	0.7	1.0	-0.9	-0.5	-1.0
Waist Hip Ratio (WHR)	0.4	2.0	5.1	-2.2	1.0	0.1
Respiratory disease	0.4	0.8	2.0	-1.4	0.4	0.4
Type 2 Diabetes (T2D) (2018)	0.4	0.7	1.1	-0.9	0.2	-1.1
Tanning	0.4	4.5	10.2	-3.2	0.1	-1.8
Medication: Simvastatin	0.4	0.6	1.6	1.3	-0.0	-0.5
Hip circumference	0.4	1.6	2.9	1.7	-1.2	0.6
Standing height	0.4	3.8	6.2	-2.1	2.5	-1.0
Medication for pain relief, constipation, heartburn	0.4	0.6	1.0	-0.0	-1.0	-0.9
Medication: Blood pressure	0.4	0.7	1.5	-1.2	-0.6	-0.6
Pulse rate, automated reading	0.4	1.4	2.7	-1.6	1.2	0.2
Guilty feelings	0.4	0.5	0.9	0.9	0.4	-0.8
Leg fat percentage (left)	0.4	1.5	2.1	1.3	-1.5	0.8
Breast Cancer	0.3	0.6	1.4	0.5	1.2	0.6
Type 2 Diabetes (T2D) (2012)	0.3	0.4	0.8	0.4	0.9	0.3
Heel T-Score	0.3	2.3	3.8	-1.2	1.9	1.3
Height	0.3	6.3	7.5	-2.5	2.7	-2.2
Lung FEV1/FVC ratio	0.3	1.7	2.8	-1.1	-1.0	-1.7
Neuroticism	0.3	0.7	1.8	1.4	-0.2	-0.5
Medication: Co-codamol	0.3	0.3	0.4	-0.6	-0.6	-0.4
Impedance of leg (right)	0.3	1.2	3.3	0.5	1.8	0.4
High blood pressure	0.3	0.9	2.6	0.3	-0.3	-1.6
Sitting height	0.3	2.3	4.8	-2.2	-1.1	-0.9
Body mass index (BMI)	0.3	1.5	3.5	0.8	-1.9	0.4
Nervous feelings	0.3	0.5	0.8	-0.9	-0.1	-0.9
Falls in the last year	0.3	0.4	0.7	-0.5	-0.9	0.6
Medication: Cholesterol lowering	0.3	0.5	1.4	-1.2	-0.3	-0.2
Body fat percentage	0.3	1.3	2.9	1.0	-1.7	0.3
Leg fat percentage (right)	0.3	1.2	1.3	1.0	-1.1	1.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.4	0.9	-1.0	0.4	-0.3
Leg fat mass (right)	0.3	1.1	2.8	0.4	-1.7	0.6
Had major operations	0.3	0.3	0.8	-0.1	0.9	-0.4
Family relationship satisfaction	0.3	0.3	0.4	0.7	0.4	0.6
Leg fat-free mass (right)	0.3	1.5	1.9	-1.4	-1.1	-1.2
Osteoporosis (self-reported)	0.3	0.3	0.8	0.3	-0.4	0.9
Leg predicted mass (right)	0.3	1.4	1.7	-1.3	-1.0	-1.1
Arm fat mass (left)	0.3	1.0	2.8	0.6	-1.7	0.1
Ever taken oral contraceptive pill	0.3	0.4	0.4	0.6	-0.6	-0.6
Eye problems/disorders: Glaucoma	0.3	0.4	1.0	0.2	-0.3	-1.0
High cholesterol (Self-reported)	0.3	0.5	0.9	-0.7	-0.2	0.9
Risk taking	0.3	0.5	1.0	0.5	-1.0	-0.4
Ever depressed for a whole week	0.3	0.4	0.6	0.8	-0.0	0.7
Vascular/heart problems diagnosed by doctor	0.3	0.7	1.6	0.1	0.7	1.3
Leg fat mass (left)	0.3	1.2	3.1	0.5	-1.8	0.5
Body Mass Index (BMI) (2010)	0.2	0.3	0.6	0.5	0.2	0.8
Crohns Disease (2012)	0.2	0.3	0.5	0.7	0.6	-0.1
HDL Cholesterol	0.2	0.4	0.7	-0.8	0.5	-0.5
Other serious medical condition/disability diagnosed by doctor	0.2	0.2	0.6	-0.3	-0.7	-0.1
Leg fat-free mass (left)	0.2	1.2	1.9	-1.4	-1.0	-0.8
Trunk fat percentage	0.2	0.9	2.2	0.7	-1.5	0.3
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	0.5	0.2	-0.0	0.7
Impedance of leg (left)	0.2	0.9	1.9	0.9	1.4	0.0
Leg predicted mass (left)	0.2	1.1	1.9	-1.4	-0.9	-0.7
Impedance of arm (right)	0.2	0.9	2.3	0.3	-0.6	-1.5
Trunk fat-free mass	0.2	1.0	1.7	-1.1	1.3	-0.1
Impedance of arm (left)	0.2	0.7	1.3	0.8	-0.5	-1.1
Arm fat mass (right)	0.2	0.9	2.3	0.5	-1.5	0.2
Trunk predicted mass	0.2	1.0	1.9	-1.1	1.4	0.0
Gout (self-reported)	0.2	0.3	0.5	-0.7	-0.3	0.5
Whole body fat mass	0.2	0.9	2.5	0.5	-1.6	0.1
Alcohol intake frequency.	0.2	0.4	1.2	-1.1	0.2	-0.2
Handedness (chirality/laterality): Left-handed	0.2	0.2	0.4	0.4	0.4	0.6
Medication: Aspirin	0.2	0.3	0.6	-0.8	0.6	0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.4	0.6	-0.8	-0.0	0.8
Tinnitus: Yes, now most or all of the time	0.2	0.2	0.6	0.1	0.8	0.1
Cholesterol lowering medication	0.2	0.3	0.8	-0.1	-0.9	-0.5
Worry (Nagel 2018)	0.1	0.3	0.8	0.1	0.2	-0.9
Irritable Bowel Disease (IBD)	0.1	0.2	0.6	-0.1	-0.2	0.8
Blood Eosinophil Count	0.1	0.5	0.8	-0.9	0.6	-0.7
Hair Pigment	0.1	1.6	3.2	-1.8	-0.5	1.1
Sensitivity / hurt feelings	0.1	0.1	0.2	-0.4	-0.3	0.3
Systolic blood pressure, automated reading	0.1	0.3	0.6	0.3	-0.8	-0.5
Eye problems/disorders: Diabetes related eye disease	0.1	0.1	0.2	0.1	-0.4	0.4
Trunk fat mass	0.1	0.6	1.6	0.2	-1.3	0.2
Waist circumference	0.1	0.2	0.4	0.4	-0.6	0.2
Medication: Ramipril	0.1	0.1	0.3	-0.6	0.1	-0.2
Weight	0.1	0.3	0.8	-0.1	-0.9	-0.2
Arm fat-free mass (right)	0.1	0.4	0.6	-0.8	0.6	0.5
Migraine (self-reported)	0.1	0.1	0.1	0.3	-0.2	0.3
Medication: Allopurinol	0.1	0.2	0.5	-0.7	-0.1	0.1
Arm predicted mass (right)	0.1	0.7	0.9	-1.0	0.8	0.7
Comparative height size at age 10	0.1	0.5	0.8	-0.4	0.9	-0.6
Whole body fat-free mass	0.1	0.6	1.6	-1.3	0.4	-0.3
Breast cancer (self-reported)	0.1	0.1	0.2	-0.3	0.4	-0.2
Whole body water mass	0.1	0.7	1.7	-1.3	0.5	-0.4
Mother’s age at death	0.1	0.1	0.3	-0.0	0.1	-0.5
Basal metabolic rate	0.1	0.5	1.3	-1.1	-0.1	-0.4
Arm fat-free mass (left)	0.1	0.5	1.2	-1.1	0.6	0.0
Arm predicted mass (left)	0.1	0.7	1.0	-0.9	1.0	0.5
Blood Red Count	0.0	0.2	0.3	0.5	0.2	-0.4
Chronotype (morning person)	0.0	0.1	0.1	-0.2	-0.2	-0.4
Supplements: Glucosamine	0.0	0.0	0.0	0.1	-0.0	0.1
Heart attack	0.0	0.0	0.1	-0.0	0.1	-0.3
Supplements: Calcium	0.0	0.0	0.1	-0.1	0.3	0.1
Heart attack/myocardial infarction (self-reported)	0.0	0.1	0.1	0.3	0.1	-0.2
Impedance of whole body	0.0	0.2	0.3	0.6	0.3	-0.4

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