TWAS hub - DPH1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Brain Cerebellar Hemisphere	0.3460	0.1100	3.9e-03	0.308	NA	0.231	NA	0.311	1.2e-08	NA	1.3e-06	NA	9.8e-09
2	GTEx	Brain Cerebellum	0.5230	0.1070	6.8e-05	0.296	NA	0.263	NA	0.307	2.1e-09	NA	2.1e-08	NA	8.9e-10
3	GTEx	Cells Transformed fibroblasts	0.2840	0.0590	4.9e-07	0.116	NA	0.229	NA	0.220	5.5e-09	NA	4.0e-17	NA	1.8e-16
4	GTEx	Esophagus Muscularis	0.2130	0.0620	2.3e-04	0.077	NA	0.057	NA	0.093	1.9e-05	NA	2.2e-04	NA	2.9e-06
5	GTEx	Nerve Tibial	0.3405	0.0624	6.5e-07	0.106	NA	0.189	NA	0.200	6.2e-08	NA	2.3e-13	NA	3.9e-14
6	GTEx	Ovary	0.6740	0.1590	2.4e-03	0.378	NA	0.282	NA	0.394	3.0e-10	NA	1.2e-07	NA	1.0e-10
7	GTEx	Pituitary	0.6570	0.0970	4.6e-05	0.470	NA	0.385	NA	0.454	2.0e-13	NA	1.1e-10	NA	7.1e-13
8	GTEx	Skin Sun Exposed Lower leg	0.2100	0.0580	2.3e-04	0.014	NA	0.039	NA	0.025	2.4e-02	NA	3.4e-04	NA	3.5e-03
9	GTEx	Thyroid	0.2770	0.0560	4.0e-06	0.233	NA	0.236	NA	0.235	8.0e-18	NA	4.6e-18	NA	5.9e-18
10	ROSMAP	Brain Pre-frontal Cortex	0.5064	0.0371	0.0e+00	0.504	0.447	0.507	0.506	0.513	9.0e-75	1.2e-63	1.4e-75	3.5e-75	8.6e-77
11	TCGA	Kidney Renal Clear Cell Carcinoma	0.0358	0.0194	9.6e-03	0.014	0.019	0.014	NA	0.018	9.8e-03	2.6e-03	8.4e-03	NA	3.9e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
Guilty feelings	7.2	10.8	15.9	3.2	3.1	3.4	3.7	3.6	3.1	3.2	1.3	3.5	3.2	4.0
Medication: Amlodipine	7.1	9.9	16.8	3.4	3.5	3.4	2.8	3.0	4.1	3.4	0.4	3.7	2.7	2.8
Illnesses of father: None of the above (group 1)	6.7	8.2	10.7	-2.7	-2.8	-2.9	-3.0	-3.3	-3.3	-2.6	-2.6	-2.6	-3.1	-2.6
Illnesses of father: Heart disease	6.2	8.6	14.3	2.6	2.7	3.0	2.9	3.5	2.7	2.6	2.3	2.9	3.8	2.8
Noisy workplace	5.6	6.9	9.5	2.3	2.6	2.7	3.1	3.0	2.2	2.4	1.8	2.6	3.0	2.9
Heel T-Score	4.6	36.2	84.8	9.2	9.2	5.4	-0.1	2.2	8.3	8.3	-0.9	7.6	0.7	0.0
Length of working week for main job	4.5	4.9	8.3	2.3	2.4	2.4	2.1	2.2	2.9	2.2	0.7	2.4	2.3	1.8
Chronic bronchitis/emphysema (mother)	4.3	5.0	7.6	1.9	2.5	2.8	2.2	2.4	2.1	2.0	1.1	2.1	2.7	2.3
Multivitamins +/- minerals	4.1	5.2	7.6	-2.1	-2.1	-2.6	-2.7	-2.7	-2.8	-1.9	-0.9	-2.3	-2.3	-2.1
Worry too long after embarrassment	4.1	6.8	11.8	1.8	2.3	3.0	3.4	3.1	2.0	1.9	0.9	2.4	3.4	3.2
Illnesses of siblings	3.7	5.1	10.8	-1.7	-2.3	-3.3	-2.1	-2.4	-2.1	-1.8	0.1	-1.9	-2.6	-3.1
Seen a psychiatrist for nerves, anxiety, tension or depression	3.6	4.6	7.2	2.2	1.7	2.2	2.2	2.2	2.7	2.3	1.6	2.0	2.2	2.0
Breast Cancer	3.5	8.4	12.5	3.0	3.3	2.8	2.5	2.6	3.5	3.5	3.0	3.3	1.8	1.9
Health satisfaction	3.5	4.5	12.5	1.2	0.9	2.5	2.8	2.8	1.2	1.1	1.2	1.2	3.5	2.7
Diverticular disease/diverticulitis (self-reported)	3.3	3.9	5.8	2.4	2.2	2.1	1.6	1.8	2.2	2.4	1.8	2.1	1.2	1.8
Falls in the last year	3.3	4.5	6.4	1.7	2.2	1.6	2.4	2.5	2.2	1.8	2.1	2.0	2.2	2.5
Neuroticism score	3.2	6.7	13.2	2.1	2.0	2.6	3.4	3.0	1.9	1.9	0.2	2.5	3.4	3.6
Frequency of depressed mood in last 2 weeks	3.1	4.4	7.5	2.7	2.0	1.9	1.9	2.0	2.7	2.4	0.4	2.5	1.3	2.1
High blood pressure (siblings)	3.1	4.4	8.9	1.9	1.8	3.0	2.1	2.3	2.1	2.1	-0.3	1.8	2.4	2.3
Medication: Blood pressure	3.0	5.3	8.7	2.1	1.9	2.9	2.6	2.6	2.8	2.1	0.3	1.9	3.0	2.0
Vitamin and mineral supplements	2.9	3.9	7.1	1.8	1.9	2.7	2.3	2.3	2.5	1.6	0.6	1.8	1.8	1.7
Heel bone mineral density (BMD) T-score, automated (left)	2.9	6.6	16.7	3.3	4.1	2.8	0.7	1.4	3.2	3.4	1.0	3.4	0.1	0.3
Medication for cholesterol, blood pressure or diabetes	2.9	4.8	8.9	-1.9	-1.7	-2.9	-2.5	-2.5	-2.3	-1.9	-0.5	-1.9	-3.0	-1.8
Hypertension (Self-reported)	2.9	8.0	16.1	2.0	1.7	3.4	3.9	3.7	2.1	1.9	0.9	1.8	4.0	3.4
Average weekly beer plus cider intake	2.7	4.0	5.9	1.9	2.1	2.2	2.4	2.2	2.2	1.8	0.4	1.6	2.4	1.7
Had other major operations	2.6	3.2	6.1	2.2	1.9	2.2	1.3	1.5	2.5	2.3	0.7	1.9	1.2	1.3
Medication: Simvastatin	2.6	3.8	10.1	1.1	1.6	2.7	2.4	2.5	1.4	1.5	0.2	1.4	3.2	1.9
Depression (Nagel 2018)	2.5	3.7	8.4	2.6	2.1	1.6	1.4	1.6	2.9	2.3	0.1	2.0	1.3	2.0
Relative age voice broke	2.5	3.9	6.6	2.0	1.8	1.9	1.8	1.9	1.7	1.9	2.0	2.3	1.8	2.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.5	2.9	5.6	1.9	2.0	2.4	1.2	1.5	2.2	1.7	0.7	1.7	1.0	1.7
Vascular/heart problems diagnosed by doctor	2.5	6.8	15.8	-1.6	-1.3	-3.4	-3.6	-3.4	-1.8	-1.6	-0.7	-1.7	-4.0	-3.1
High blood pressure	2.4	6.6	13.3	1.8	1.4	3.2	3.6	3.4	1.8	1.7	0.3	1.6	3.6	3.2
Financial difficulties in last 2 years	2.4	3.2	8.8	0.8	0.6	1.9	3.0	2.4	0.9	0.7	1.5	0.8	2.7	2.0
Worrier / anxious feelings	2.3	4.3	9.7	1.4	1.8	1.1	3.1	2.5	1.0	1.1	1.8	1.9	2.5	3.1
Frequency of unenthusiasm / disinterest in last 2 weeks	2.2	2.9	4.3	2.1	1.7	1.9	1.8	1.8	1.9	1.8	0.9	1.8	1.4	1.5
Hair/balding pattern: Pattern 2	2.2	2.8	5.1	-2.0	-1.3	-2.3	-1.8	-1.9	-1.5	-1.4	-0.8	-1.4	-2.1	-1.1
Taking other prescription medications	2.1	3.3	7.3	1.2	0.8	2.7	2.1	2.2	1.6	1.2	1.4	1.4	2.5	1.8
Medication: Ramipril	2.1	2.7	6.4	1.5	1.3	1.5	1.6	1.9	2.2	1.4	0.8	1.2	2.5	1.4
Frequency of tiredness / lethargy in last 2 weeks	2.1	3.4	6.1	2.1	1.8	1.5	2.1	2.0	2.5	1.8	0.6	2.0	1.4	1.9
Medication: Lansoprazole	2.1	2.4	3.8	1.8	1.4	1.2	1.5	1.8	1.5	1.7	1.3	1.4	1.9	1.2
Pulse rate, automated reading	2.1	6.7	14.4	1.4	1.8	2.6	3.6	3.5	2.2	1.2	2.0	2.2	3.8	2.6
Pain all over the body in last month	2.0	2.1	4.2	0.7	1.0	1.2	2.1	1.8	0.9	0.6	1.7	1.2	1.9	1.9
Overall health rating	2.0	4.3	11.0	1.4	1.5	2.0	3.0	2.7	1.6	1.3	1.7	1.4	3.3	1.6
Blood Platelet Count	1.9	21.5	57.5	-6.2	-6.7	-7.6	1.4	-1.0	-5.5	-6.0	0.6	-5.1	-0.1	-1.3
Neuroticism	1.9	4.5	9.2	1.6	1.9	2.1	2.8	2.4	1.5	1.3	0.8	1.8	3.0	2.8
Hand grip strength (right)	1.9	5.0	11.1	2.0	1.8	2.2	2.4	2.4	1.8	2.0	3.3	1.9	2.2	2.3
Pulse rate	1.9	3.2	5.2	1.4	1.2	1.4	2.3	2.3	1.9	1.3	1.5	2.0	2.1	1.9
Depression (self-reported)	1.9	2.3	4.7	2.2	1.6	0.7	0.9	1.3	1.9	1.8	-0.2	2.0	0.7	1.8
Long-standing illness, disability or infirmity	1.9	2.9	4.5	1.5	1.5	2.0	2.1	2.1	2.1	1.4	0.7	1.5	1.6	1.6
Pain type(s) experienced in last month: Hip pain	1.9	2.4	4.8	1.0	1.7	1.2	1.9	1.7	1.1	0.8	2.2	1.0	1.9	1.9
Past tobacco smoking	1.8	3.3	6.6	-2.0	-2.1	-1.6	-1.0	-1.6	-2.6	-2.1	-1.5	-1.9	-1.7	-1.5
Heel bone mineral density (BMD) T-score, automated (right)	1.8	4.2	10.0	2.7	3.2	2.4	0.0	0.7	2.4	2.9	0.9	2.7	-0.3	0.0
Mouth/teeth dental problems: Dentures	1.8	3.0	8.1	1.0	1.4	2.1	1.9	2.0	1.4	1.2	0.9	0.9	2.8	2.2
Tense / ‘highly strung’	1.8	3.1	5.8	1.9	1.5	1.7	1.8	1.9	1.4	1.7	0.1	1.8	2.4	2.0
Maternal smoking around birth	1.7	2.5	7.2	1.8	2.7	1.5	0.8	1.2	1.8	1.8	1.3	1.7	1.3	0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	1.7	2.7	4.6	2.1	1.8	1.7	1.1	1.5	1.8	1.8	0.4	1.6	1.2	2.1
Ovarian Cancer	1.6	2.2	5.0	-1.2	-1.4	-1.1	-1.9	-1.7	-1.1	-1.0	0.3	-1.4	-1.9	-2.2
Smoking Status	1.6	3.8	8.3	2.5	2.8	1.9	0.4	1.3	2.9	2.7	0.7	2.4	1.0	0.2
Lung FEV1/FVC ratio	1.6	8.0	15.3	-3.6	-3.6	-3.2	-1.3	-2.3	-3.9	-3.4	-0.8	-3.1	-2.3	-1.6
Hand grip strength (left)	1.6	4.1	5.5	1.9	2.2	2.1	2.0	1.9	1.9	1.9	2.3	1.9	1.7	2.3
Current tobacco smoking	1.6	2.6	5.6	2.1	2.1	1.2	0.8	1.1	2.3	2.4	-0.3	2.2	0.4	0.1
Medication: Atenolol	1.6	2.0	5.0	1.2	0.8	1.9	1.4	1.6	1.7	1.0	0.6	0.8	2.2	1.1
Medication: Cholesterol lowering	1.6	2.4	4.6	1.4	1.2	2.1	1.6	1.7	1.5	1.5	0.3	1.5	2.1	1.2
Smoking status: Current	1.6	2.5	5.8	2.2	2.1	1.0	0.4	0.8	2.4	2.4	-0.3	2.1	-0.0	-0.4
Mother’s age at death	1.6	2.0	5.3	-0.7	-0.9	-1.4	-1.9	-2.0	-1.0	-0.8	-1.0	-1.2	-2.3	-1.6
Heart attack/myocardial infarction (self-reported)	1.6	2.0	4.8	1.7	1.7	1.5	0.9	1.1	2.2	1.6	0.4	1.5	1.1	1.0
Deep venous thrombosis (DVT) (self-reported)	1.6	2.1	6.6	1.9	1.9	0.4	0.8	1.2	2.6	1.9	-0.1	1.7	0.7	0.5
Alzheimer’s Disease (in father)	1.5	1.6	2.7	-1.2	-0.9	-1.3	-1.0	-1.2	-0.6	-1.2	-1.6	-1.3	-1.5	-1.6
Cardiovascular Disease	1.5	4.9	15.7	0.9	0.6	2.9	3.3	3.0	1.3	0.9	1.4	0.8	4.0	1.8
Number of treatments/medications taken	1.5	2.6	5.6	1.1	0.9	2.0	2.3	2.0	0.9	0.9	1.3	0.8	2.4	2.0
Father’s age at death	1.5	2.1	5.2	-0.6	-1.1	-1.3	-2.1	-1.9	-0.8	-0.7	-2.3	-0.7	-1.9	-1.2
Ever smoked	1.5	2.7	6.3	2.2	2.1	1.0	0.4	1.1	2.5	2.3	1.0	2.1	0.8	0.6
Serious illness, injury or assault to yourself	1.4	1.7	4.2	1.1	1.1	1.3	1.7	1.8	0.9	0.8	1.2	0.8	2.0	1.0
Sitting height	1.4	9.8	17.0	-2.5	-2.1	-4.0	-3.9	-3.9	-1.8	-2.1	-1.6	-3.4	-3.5	-4.1
Prospective memory result	1.4	1.8	2.7	-1.4	-1.4	-1.5	-1.1	-1.1	-1.0	-1.5	-1.6	-1.5	-0.5	-1.5
Illnesses of mother	1.4	1.7	2.9	-1.1	-0.9	-1.1	-1.6	-1.5	-1.4	-1.4	-0.9	-1.0	-1.7	-1.3
Illnesses of siblings: Diabetes	1.4	1.7	3.0	1.0	1.7	1.5	1.3	1.4	1.3	1.1	1.0	1.0	1.4	1.4
Leg fat percentage (left)	1.4	5.1	11.1	1.4	1.5	3.3	3.2	2.9	1.8	1.6	1.7	1.4	2.7	2.0
Ever had prostate specific antigen (PSA) test	1.4	1.6	5.2	1.7	1.4	2.3	0.4	0.7	1.2	1.6	-0.4	1.3	0.3	1.2
Age started oral contraceptive pill	1.4	1.8	3.0	1.5	1.6	0.8	1.3	1.4	1.7	1.5	-0.1	1.7	1.1	1.3
Rheumatoid Arthritis	1.3	1.8	4.9	0.6	0.6	2.2	1.8	1.6	0.9	0.4	1.1	0.7	1.7	1.7
Blood Eosinophil Count	1.3	10.0	16.7	-3.9	-3.6	-3.3	-2.8	-2.8	-3.7	-4.1	-0.3	-3.8	-2.0	-2.4
Systolic blood pressure, automated reading	1.3	3.7	6.2	-2.2	-2.4	-0.8	2.1	0.9	-2.1	-2.5	1.3	-2.1	2.4	1.2
Frequency of tenseness / restlessness in last 2 weeks	1.3	2.0	3.0	1.5	1.4	1.4	1.7	1.6	1.6	1.1	-0.6	1.2	1.4	1.5
Heart attack	1.3	1.6	4.0	1.6	1.6	1.3	0.7	0.9	2.0	1.5	0.1	1.4	0.9	0.9
Medication: Ibuprofen (e.g. Nurofen)	1.3	1.7	4.6	1.1	0.2	0.1	2.0	1.6	0.4	0.6	2.1	0.6	1.3	1.8
Ever highly irritable/argumentative for 2 days	1.3	1.5	3.0	1.3	1.5	1.7	1.4	1.2	1.2	1.0	0.5	0.9	1.2	1.3
Blood clot in the leg (DVT)	1.3	1.7	5.5	1.7	1.7	0.3	0.6	1.1	2.3	1.6	0.1	1.5	0.7	0.4
Leg fat percentage (right)	1.3	4.6	10.5	1.4	1.4	3.2	3.0	2.7	1.8	1.5	1.8	1.4	2.5	1.8
Reason for reducing amount of alcohol drunk: Health precaution	1.3	1.5	3.1	-1.6	-1.4	-1.5	-0.7	-0.9	-1.7	-1.2	-1.0	-1.1	-0.4	-1.1
Medication: Seretide 50 evohaler	1.3	1.6	2.9	1.1	1.7	0.9	0.9	1.0	1.5	1.5	0.5	1.5	1.1	1.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.3	1.5	4.9	-1.2	-1.0	-1.3	-1.3	-1.2	-0.8	-0.9	-0.7	-1.5	-0.5	-2.2
Systolic Blood Pressure	1.2	5.8	15.1	-1.7	-2.0	0.2	3.9	2.3	-1.6	-1.8	2.9	-1.3	3.7	2.6
Wheeze or whistling in the chest in last year	1.2	2.2	4.1	1.6	1.8	1.3	1.5	1.5	2.0	1.5	0.6	1.9	1.1	1.1
Qualifications: NVQ or HND or HNC or equivalent	1.2	1.4	4.3	0.5	1.0	1.2	1.7	1.5	0.4	0.5	0.9	0.5	2.1	1.4
Eye problems/disorders: Cataract	1.2	1.4	2.7	1.4	0.7	1.6	1.1	1.4	1.2	1.3	0.8	0.9	1.2	0.7
Back pain experienced in last month	1.2	1.8	5.3	1.1	1.3	0.7	1.2	1.1	1.8	1.2	2.3	1.3	0.8	0.7
Financial situation satisfaction	1.2	1.5	2.7	1.2	0.7	1.2	1.6	1.4	1.2	1.1	0.2	1.4	1.3	1.6
Supplements: Fish oil (including cod liver oil)	1.2	1.5	4.5	-1.2	-1.0	-1.6	-1.1	-1.2	-2.1	-1.1	-1.0	-1.1	-1.1	-0.3
Fractured/broken bones in last 5 years	1.2	1.5	3.6	-1.2	-1.9	-1.1	-1.0	-1.1	-1.7	-1.5	0.1	-1.3	-0.7	-0.9
Sensitivity / hurt feelings	1.1	2.0	4.4	0.9	1.1	1.5	1.7	1.6	1.0	1.0	0.7	1.3	2.1	1.8
Stomach or abdominal pain in last month	1.1	1.4	4.1	1.2	0.9	1.3	1.1	1.2	1.1	0.9	-0.0	1.0	1.3	2.0
Shortness of breath walking on level ground	1.1	1.3	3.1	1.3	0.9	1.8	0.8	1.1	1.2	0.8	0.1	0.8	1.2	1.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.1	1.4	3.0	1.6	0.7	1.4	1.1	1.1	0.9	1.1	1.7	1.2	1.1	0.1
Illness, injury, bereavement, stress in last 2 years	1.1	1.4	5.5	-0.5	0.0	-0.9	-1.7	-1.7	-0.4	-0.4	-0.0	-0.7	-2.4	-1.3
Supplements: Vitamin C	1.1	1.3	3.4	-0.6	-0.9	-1.8	-1.1	-1.2	-1.3	-0.5	1.5	-0.7	-1.2	-0.9
Smoking status: Previous	1.1	1.6	3.4	0.9	1.3	1.3	0.6	1.2	1.4	1.0	1.6	0.9	1.8	1.6
Primary Biliary Cirrhosis	1.0	1.5	2.7	1.0	1.0	1.2	1.3	1.5	1.0	1.1	0.9	1.4	1.1	1.6
Triglycerides	1.0	1.7	2.9	-1.4	-1.2	-1.4	-1.2	-1.3	-1.6	-1.5	0.2	-1.7	-0.8	-1.2
Ever had hysterectomy (womb removed)	1.0	1.1	2.9	1.2	1.1	1.7	0.7	1.0	1.1	0.9	0.3	1.0	0.9	1.0
Supplements: Glucosamine	1.0	1.3	3.5	-0.9	-0.8	-1.9	-1.3	-1.3	-0.9	-1.0	-1.0	-0.9	-1.0	-1.4
Nervous feelings	1.0	1.9	6.7	-0.5	-0.1	1.1	2.2	1.5	-0.5	-0.7	0.6	0.1	2.6	2.1
Heart disease (mother)	1.0	1.2	1.8	1.2	1.1	0.8	1.1	1.2	1.2	1.3	1.1	1.2	0.9	1.0
Mood swings	1.0	1.8	5.7	0.7	0.4	0.9	1.9	1.6	0.6	0.6	-0.8	1.0	2.0	2.4
Mineral and other dietary supplements	1.0	1.3	3.0	0.5	0.7	1.7	1.0	1.2	1.6	0.7	1.6	0.8	1.3	0.5
Osteoarthritis (self-reported)	1.0	1.3	3.3	1.8	1.6	0.5	-0.3	0.3	1.4	1.6	-0.0	1.7	-0.2	0.7
Ever depressed for a whole week	1.0	1.2	2.4	1.1	1.0	1.1	1.2	1.1	0.9	0.9	0.6	0.9	1.3	1.6
Irritable Bowel Disease (IBD)	0.9	2.1	4.7	-0.8	-0.1	-1.4	-2.1	-2.0	-0.9	-0.9	-1.5	-0.9	-1.7	-2.2
Ulcerative Colitis	0.9	1.3	3.2	-0.8	-0.4	-0.7	-1.6	-1.4	-0.6	-1.0	-1.8	-0.5	-1.3	-1.5
Relative age of first facial hair	0.9	1.9	5.3	0.9	0.7	1.1	1.8	1.5	0.9	1.1	2.3	1.4	1.3	1.6
Severe depression (siblings)	0.9	1.0	3.7	0.9	1.0	0.7	0.8	1.0	1.2	0.7	1.9	0.7	0.9	0.7
Impedance of arm (right)	0.9	4.0	11.1	-3.3	-3.1	-2.1	0.1	-0.7	-2.8	-2.6	0.1	-1.9	0.2	-0.1
Knee pain experienced in last month	0.9	1.5	2.7	1.4	1.2	1.2	1.6	1.5	1.2	0.8	0.1	0.7	1.4	1.4
Mouth/teeth dental problems: Mouth ulcers	0.9	1.4	4.4	-1.1	-1.1	-1.1	-1.1	-1.1	-2.1	-1.5	-0.7	-1.1	-0.8	-0.8
Eye problems/disorders: Glaucoma	0.9	1.1	3.1	-0.0	0.1	-1.7	-1.3	-1.2	-0.2	0.2	-0.7	-0.2	-1.8	-1.4
Illnesses of father: High blood pressure	0.9	1.2	3.1	1.0	0.5	1.4	1.2	1.3	0.6	0.7	1.2	0.4	1.8	1.1
Alcohol drinker status: Never	0.9	1.0	2.6	0.9	0.7	1.3	1.3	1.2	0.4	0.6	1.0	0.5	1.6	1.0
Neuroticism (Nagel 2018)	0.8	2.0	5.7	0.6	1.0	1.5	1.8	1.4	1.1	0.4	0.5	0.7	2.2	2.4
LDL Cholesterol	0.8	1.3	2.7	-1.2	-1.0	-1.7	-1.0	-1.3	-1.2	-0.9	0.1	-1.3	-0.9	-1.3
Medication for hormone replacement therapy	0.8	0.9	2.1	-1.2	-1.5	0.2	0.5	0.4	-1.1	-1.0	1.3	-0.9	1.0	-0.5
Qualifications: None of the above	0.8	1.7	4.9	0.7	1.2	0.9	2.1	1.7	0.4	0.7	0.7	0.8	2.2	1.4
Comparative height size at age 10	0.8	4.2	12.5	-0.0	-0.0	-2.2	-3.1	-2.7	0.8	0.1	-0.8	-1.1	-3.5	-3.0
Suffer from ‘nerves’	0.8	1.2	3.4	-0.6	-0.4	-0.2	1.8	1.1	-0.7	-0.8	1.2	-0.2	1.8	1.6
Handedness (chirality/laterality): Left-handed	0.8	1.0	2.9	0.3	0.6	0.5	1.3	1.3	0.9	0.2	1.7	0.7	1.5	0.7
Number of self-reported non-cancer illnesses	0.8	1.4	2.7	1.0	0.9	1.3	1.3	1.4	1.0	0.9	1.1	1.0	1.6	1.2
Irritability	0.8	1.3	2.5	1.6	1.1	1.3	0.7	1.0	1.2	1.3	-0.6	1.5	0.6	1.0
Myopia	0.8	1.1	2.1	-0.7	-0.7	-0.6	-1.4	-1.2	-0.4	-0.5	-1.4	-1.0	-1.3	-1.5
Cholesterol lowering medication	0.8	1.2	3.3	0.4	1.3	1.8	1.1	1.2	0.4	0.9	-0.5	0.8	1.7	1.0
Type 2 Diabetes (T2D) (2012)	0.7	0.8	2.0	-0.9	-1.0	-1.0	-0.3	-0.5	-1.4	-1.3	0.6	-1.0	0.2	-0.5
Blood White Count	0.7	5.0	15.7	-1.7	-1.8	-4.0	2.1	1.2	-1.7	-1.6	3.8	-1.4	2.2	-0.4
Townsend deprivation index at recruitment	0.7	0.9	2.7	0.7	0.7	0.6	1.3	1.2	0.9	0.7	1.6	0.6	0.5	1.0
Average weekly fortified wine intake	0.7	0.8	2.7	0.4	0.7	-0.7	-1.5	-1.2	-0.3	0.3	-0.4	0.1	-1.6	-1.2
Alcohol usually taken with meals	0.7	1.1	3.0	1.7	1.3	0.5	-0.4	0.2	1.4	1.3	1.2	1.5	0.0	0.0
Time employed in main current job	0.7	0.8	1.7	-0.5	-0.3	-0.9	-1.2	-1.3	-0.8	-0.7	-0.7	-0.9	-1.3	-0.9
Lung cancer (father)	0.7	0.8	1.9	-0.3	0.3	-0.9	-1.1	-1.1	-0.4	-0.2	-1.4	-0.5	-1.1	-1.2
Impedance of arm (left)	0.7	3.4	9.8	-3.1	-2.8	-2.2	0.1	-0.7	-2.6	-2.3	0.2	-1.6	0.3	-0.2
Exposure to tobacco smoke at home	0.7	0.8	2.6	-0.0	-0.1	0.7	1.2	1.1	0.1	-0.5	1.6	-0.5	1.4	0.5
Birth weight of first child	0.7	1.2	3.0	-1.7	-1.3	-1.0	-0.2	-0.6	-1.4	-1.7	-0.6	-1.2	-0.2	0.8
Migraine (self-reported)	0.7	0.8	2.1	-1.5	-1.2	-1.0	-0.0	-0.4	-0.9	-1.4	0.3	-1.1	-0.2	-0.1
Medication: Ibuprofen	0.7	0.8	2.7	0.5	0.1	-0.0	1.5	1.0	0.2	0.1	1.6	-0.0	0.7	1.6
Had major operations	0.7	0.9	2.5	-0.7	-1.0	0.7	0.9	0.9	-0.6	-0.7	1.2	-0.4	1.6	1.0
Diabetes diagnosed by doctor	0.7	1.1	2.8	-1.6	-1.1	-0.5	-0.1	-0.4	-1.7	-1.6	-0.5	-1.5	0.1	-0.2
Medication: Blood pressure	0.7	1.4	3.2	0.9	0.8	1.8	1.5	1.4	0.7	0.8	-0.5	0.6	1.4	1.6
Diastolic blood pressure, automated reading	0.7	2.2	7.3	-0.6	-1.2	0.9	2.7	1.9	-0.4	-0.8	0.7	-0.8	2.6	1.6
Pain experienced in last month	0.7	1.2	2.9	-0.1	-0.4	-0.4	-1.7	-1.4	-0.9	-0.0	-1.6	-0.3	-1.4	-1.4
Leg fat mass (left)	0.7	2.8	8.7	1.2	1.2	3.0	2.0	1.9	1.8	1.0	1.9	0.5	1.7	0.9
Worry (Nagel 2018)	0.6	1.2	4.1	-0.2	0.3	0.4	1.7	1.0	0.0	-0.6	0.7	0.0	2.0	1.9
Ulcerative Colitis (UC)	0.6	1.1	2.5	-0.8	-0.3	-0.9	-1.6	-1.4	-0.5	-1.1	-0.6	-1.0	-1.1	-1.3
Age at First Birth	0.6	0.8	1.5	-1.2	-0.9	-1.2	-0.9	-1.0	-0.8	-1.0	-0.2	-0.5	-1.1	-0.7
HbA1C	0.6	0.7	3.0	-0.4	-0.4	-1.2	-0.8	-0.7	0.3	-0.8	-1.7	-0.5	-0.7	-0.1
Diabetes (mother)	0.6	0.8	2.4	-0.9	-1.1	0.4	1.0	0.7	-0.6	-1.0	1.0	-0.6	1.5	0.3
Arm fat percentage (right)	0.6	2.4	6.6	-0.5	-0.8	2.6	2.3	1.8	-0.1	-0.8	1.9	-0.9	2.1	1.0
Hair/balding pattern: Pattern 3	0.6	0.9	2.1	1.1	0.4	0.9	1.4	1.3	0.8	0.7	0.1	0.6	1.2	1.1
Pulse wave reflection index	0.6	0.8	1.8	-0.6	-0.8	-0.7	-1.2	-1.2	-1.3	-0.2	-0.5	-0.5	-1.0	-0.9
Glaucoma (self-reported)	0.6	0.7	1.7	0.9	0.9	-0.6	0.6	0.5	1.0	1.3	1.0	0.8	-0.0	0.1
Body fat percentage	0.6	2.4	6.2	-0.2	-0.3	2.3	2.5	2.0	0.4	-0.2	2.0	-0.3	2.3	1.1
Eye problems/disorders: None of the above	0.6	0.7	1.3	-1.1	-0.7	-1.1	-0.6	-0.8	-1.1	-1.1	0.4	-0.8	-0.4	-0.7
Emphysema/chronic bronchitis	0.6	0.7	1.6	-0.9	-0.3	-0.1	1.1	0.9	-0.3	-1.0	1.3	-0.2	1.2	0.6
Leg fat mass (right)	0.6	2.5	7.8	1.1	1.1	2.8	1.9	1.8	1.7	0.9	1.9	0.4	1.6	0.7
Chest pain or discomfort	0.6	0.9	3.5	-0.5	-0.6	0.5	0.9	1.1	0.3	-0.5	1.7	0.1	1.9	0.5
Arm fat percentage (left)	0.6	2.4	6.4	-0.4	-0.7	2.5	2.3	1.8	0.0	-0.8	1.9	-0.9	2.2	0.9
Loneliness, isolation	0.6	0.9	2.2	0.8	0.9	0.6	1.1	0.9	0.8	1.0	0.7	0.9	0.7	1.5
Qualifications: nursing, teaching	0.6	1.0	2.1	-0.4	-1.0	-1.2	-1.4	-1.3	-0.5	-0.8	-0.2	-0.7	-1.4	-1.0
Medication: Bendroflumethiazide	0.6	0.9	2.5	0.4	0.7	1.0	1.6	1.1	0.7	0.5	0.4	0.3	1.3	1.3
Basal cell carcinoma (self-reported)	0.6	0.8	1.9	1.2	0.5	0.6	0.4	0.7	0.8	1.4	0.6	1.3	1.0	0.0
Bipolar Disorder (2018)	0.5	0.8	3.7	-0.1	-0.2	-0.1	1.3	0.9	0.0	-0.1	1.9	0.4	1.3	0.8
Alzheimer’s Disease (in mother)	0.5	0.6	1.3	0.2	0.6	0.8	0.8	0.7	1.1	0.6	0.7	0.5	0.8	1.0
Crohns Disease (2017)	0.5	1.2	3.4	-0.4	0.1	-1.1	-1.3	-1.3	-0.6	-0.4	-1.8	-0.3	-1.0	-1.8
Lupus	0.5	0.8	1.8	-0.8	-1.4	-0.4	-0.5	-0.2	-1.1	-1.3	1.1	-0.9	0.5	-0.6
Average weekly spirits intake	0.5	0.6	1.2	1.0	0.8	1.0	-0.2	0.0	1.1	0.9	-0.7	1.0	-0.3	-0.3
Supplements: Zinc	0.5	0.6	1.4	1.0	1.2	-0.0	-0.3	-0.1	0.3	1.0	1.1	0.8	-0.5	0.7
Diabetes (father)	0.5	0.6	1.9	-0.8	-1.2	-0.7	0.2	0.0	-1.2	-0.7	1.4	-0.6	0.5	-0.1
Body mass index (BMI)	0.5	2.3	9.1	1.1	0.7	3.0	1.9	1.8	1.1	0.3	1.4	-0.0	1.7	0.8
Waist circumference	0.5	1.7	8.0	0.7	0.6	2.8	1.5	1.5	1.4	0.4	0.9	-0.0	1.5	0.6
Diabetes (self-reported)	0.5	0.7	1.9	-1.3	-0.8	0.1	0.5	0.2	-1.4	-1.3	-0.2	-1.1	0.6	0.5
Trunk fat-free mass	0.5	2.9	6.5	2.5	2.3	1.2	-1.6	-0.8	2.5	1.9	0.3	0.6	-1.9	-1.4
Number of live births	0.5	0.6	1.8	-0.3	-0.3	-0.1	-1.1	-1.0	-0.6	-0.7	-1.4	-0.7	-1.1	-0.3
Trunk predicted mass	0.5	2.8	6.2	2.5	2.2	1.2	-1.6	-0.8	2.5	1.9	0.4	0.5	-1.8	-1.4
Loud music exposure frequency	0.5	0.5	2.2	0.2	0.3	0.1	1.1	0.8	0.4	0.4	1.5	0.4	0.7	0.9
Arm fat-free mass (right)	0.5	2.7	7.3	2.5	2.4	1.3	-1.0	-0.3	2.7	1.9	0.6	0.8	-1.2	-1.1
Number of children fathered	0.5	0.6	1.9	0.7	1.1	1.4	0.6	0.6	0.6	0.5	0.5	0.5	0.7	0.2
Arm predicted mass (right)	0.5	2.4	6.6	2.3	2.3	1.2	-0.9	-0.3	2.6	1.8	0.5	0.7	-1.2	-1.2
Alcohol intake frequency.	0.5	1.1	4.2	-0.3	-0.4	0.3	1.6	1.1	-0.7	-0.5	2.0	-0.1	1.6	0.6
Medication: Aspirin	0.5	0.7	1.4	-1.2	-1.0	0.2	-0.7	-0.7	-0.9	-1.1	-0.3	-1.2	0.1	-0.6
Tinnitus: Yes, now most or all of the time	0.5	0.5	2.8	0.2	0.1	0.0	-0.9	-0.8	0.2	-0.1	-1.7	-0.1	-1.3	-0.2
Fasting Glucose	0.4	0.5	2.6	-0.2	0.4	-1.0	-0.4	-0.4	-0.2	-0.2	-1.6	0.3	-0.7	-0.6
Allergy or Eczema	0.4	1.0	2.5	1.4	1.6	0.8	0.2	0.4	0.4	1.2	1.0	1.2	-0.5	1.2
Type 2 Diabetes (T2D) (2018)	0.4	0.7	1.5	-1.2	-0.7	-0.6	-0.5	-0.7	-0.9	-1.1	0.1	-1.0	-0.6	-0.9
Lung FVC	0.4	1.8	5.1	-0.8	-2.2	-1.3	-0.8	-0.9	-0.6	-1.4	-2.0	-1.4	0.6	-1.6
Medication: Metformin	0.4	0.6	1.2	-1.0	-0.9	-0.6	-0.4	-0.7	-1.0	-1.1	-0.3	-1.1	-0.8	-0.2
Trunk fat percentage	0.4	1.8	4.3	-0.7	-0.7	1.7	2.1	1.5	0.0	-0.6	1.9	-0.9	2.0	0.5
Fed-up feelings	0.4	0.6	2.5	0.8	0.9	0.3	0.4	0.2	0.7	0.5	-1.6	0.9	-0.6	0.9
Hayfever, allergic rhinitis or eczema	0.4	0.9	2.2	1.1	1.2	1.1	0.6	0.8	0.2	0.7	1.5	0.8	0.2	1.2
Chronic bronchitis/emphysema (father)	0.4	0.5	1.5	0.4	1.1	0.6	0.8	0.6	1.2	0.6	0.5	0.4	0.3	0.3
Number of incorrect matches in round	0.4	0.7	3.2	0.4	0.0	0.4	1.1	0.9	-0.3	0.2	0.1	0.6	1.3	1.8
Allergy	0.4	1.0	2.7	-1.1	-1.6	-1.0	-0.6	-0.9	-0.9	-0.9	-1.2	-1.1	-0.3	-0.9
Happiness	0.4	0.5	2.2	-0.7	-1.5	-0.2	-0.5	-0.6	-1.0	-0.6	0.3	-0.6	-0.2	0.6
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.4	1.7	-0.1	-0.3	-0.4	-1.3	-0.9	0.1	0.0	-0.8	-0.1	-1.0	-0.7
Headache pain in last month	0.4	0.7	2.5	-0.5	-0.6	-0.9	1.4	0.8	-0.4	-0.7	1.6	-0.4	0.8	0.6
Birth weight	0.4	0.8	1.6	-1.1	-1.2	0.0	1.2	0.5	-1.0	-1.2	0.8	-0.9	1.0	0.3
Exposure to tobacco smoke outside home	0.4	0.5	0.9	-0.8	-0.9	-0.5	0.9	0.4	-0.1	-0.7	0.8	-1.0	0.6	-0.2
Medication for pain relief, constipation, heartburn	0.4	0.7	1.7	0.9	0.9	0.9	-0.1	0.2	1.3	1.0	-1.0	1.1	-0.4	-0.2
Age at last live birth	0.4	0.5	1.7	0.6	0.4	-0.0	-0.2	0.0	1.3	1.1	-0.2	1.3	-0.6	-0.2
Leg pain on walking	0.4	0.5	2.2	0.4	-0.2	-0.1	1.4	1.0	0.3	-0.0	0.1	0.3	1.5	0.6
Commuting to job workplace: Car/motor vehicle	0.4	0.4	1.0	-1.0	-0.9	0.1	-0.3	-0.6	-0.7	-0.8	0.2	-1.0	-0.6	-0.3
Medication: Aspirin	0.4	0.6	1.3	-1.1	-1.0	0.3	-0.5	-0.5	-0.9	-1.1	-0.0	-1.1	0.3	-0.5
Whole body fat-free mass	0.4	2.1	4.8	2.1	1.7	1.1	-1.4	-0.8	2.2	1.4	0.6	0.0	-1.7	-1.6
Medication for cholesterol	0.4	0.6	2.8	-0.1	-0.0	-1.7	-0.9	-0.9	0.4	-0.1	0.3	0.1	-1.3	-0.5
Whole body water mass	0.4	2.0	4.5	2.0	1.6	1.1	-1.4	-0.8	2.1	1.3	0.6	-0.1	-1.7	-1.6
Average weekly champagne plus white wine intake	0.4	0.6	1.4	1.1	0.7	0.5	-0.1	0.1	0.8	0.8	-0.9	1.2	-0.6	0.4
Arm fat-free mass (left)	0.4	2.0	5.3	2.2	1.9	1.5	-0.8	-0.2	2.3	1.6	0.8	0.4	-1.0	-1.0
Schizophrenia vs Biploar Disorder	0.3	0.3	1.8	-0.2	0.1	0.6	-0.4	-0.3	-0.8	0.3	-1.3	-0.6	-0.1	0.4
Alzheimer’s Disease (including proxy)	0.3	0.4	1.5	-1.2	-0.5	-0.3	-0.1	-0.4	-0.1	-0.8	-0.8	-0.9	-0.4	0.0
Reaction Time	0.3	0.6	2.4	-1.1	-1.6	-1.0	0.1	0.3	-0.6	-0.7	0.4	-0.3	1.0	0.1
Body Mass Index (BMI) (2010)	0.3	0.4	1.8	0.3	1.0	1.3	0.0	0.3	0.8	0.1	0.2	-0.1	0.5	-0.2
Coronary Artery Disease (CAD)	0.3	0.3	1.0	-0.3	0.3	0.9	0.2	0.3	-0.2	-0.7	-0.5	-0.5	1.0	0.2
Crohns Disease (2012)	0.3	0.5	2.7	-0.9	-0.3	-0.4	-0.2	-0.2	-0.9	-0.3	-1.6	0.0	-0.0	-1.0
HDL Cholesterol	0.3	0.5	1.3	0.5	0.4	0.4	1.2	1.0	0.1	0.6	0.7	0.8	0.8	1.0
Schizophrenia (2014)	0.3	0.6	2.2	-0.6	-0.7	-1.5	-0.2	-0.8	-1.5	-0.4	-0.7	-0.6	-0.0	0.1
BMI	0.3	1.6	5.3	0.6	0.2	2.3	2.1	1.9	0.7	-0.1	0.2	-0.4	1.9	0.1
Waist Hip Ratio (WHR)	0.3	1.2	3.4	-1.8	-1.1	0.3	-0.5	-0.1	-0.9	-1.2	-1.6	-1.1	1.2	-0.6
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	0.8	-0.6	-0.2	-0.4	-0.9	-0.8	-0.3	-0.5	0.1	-0.5	-0.7	-0.7
Age when periods started (menarche)	0.3	0.8	6.3	-0.2	-0.2	-0.2	0.2	0.3	0.1	-0.2	2.5	0.3	0.8	1.0
Qualifications: CSEs or equivalent	0.3	0.5	1.4	-0.9	-1.2	-0.4	0.5	0.4	-0.6	-0.8	0.5	-0.6	0.9	0.1
Mouth/teeth dental problems	0.3	0.4	1.3	0.5	0.5	-0.6	-0.1	-0.3	0.5	0.8	-0.6	0.6	-1.1	-1.0
Weight	0.3	1.3	4.9	1.4	1.2	2.2	0.4	0.6	1.7	0.9	1.4	-0.1	0.2	-0.3
Hip circumference	0.3	1.3	5.1	1.2	0.4	2.3	1.3	1.1	1.3	0.6	1.6	-0.0	0.4	0.6
Pulse wave Arterial Stiffness index	0.3	0.3	1.1	-0.4	-1.0	-0.8	0.0	-0.2	-1.1	-0.2	-0.4	-0.1	0.4	-0.6
Arm fat mass (right)	0.3	1.4	5.7	0.2	-0.1	2.4	1.5	1.3	0.5	-0.4	1.7	-0.8	1.5	0.3
Standing height	0.3	3.5	10.0	0.7	1.1	-1.4	-3.1	-2.5	1.4	1.3	0.1	-0.2	-3.2	-2.3
Mouth/teeth dental problems: Bleeding gums	0.3	0.3	0.6	0.7	-0.1	0.7	0.3	0.6	0.7	0.4	0.4	0.7	0.6	0.8
Medication: Paracetamol	0.3	0.5	1.4	-0.8	-0.5	-1.2	0.2	-0.1	-1.0	-0.6	1.1	-0.6	0.1	-0.0
Pulse wave peak to peak time	0.3	0.4	1.4	0.5	1.1	0.6	-0.2	0.1	1.2	0.4	0.5	0.2	-0.6	0.4
Angina (self-reported)	0.3	0.4	1.4	0.3	0.6	0.9	0.1	0.4	0.4	0.4	0.4	0.7	1.2	0.2
Whole body fat mass	0.3	1.4	4.6	0.3	0.2	2.2	1.6	1.3	0.9	0.1	1.9	-0.5	1.4	0.3
Family relationship satisfaction	0.3	0.3	1.2	-0.7	-1.1	0.3	-0.4	-0.4	-0.4	-0.4	0.6	-0.8	0.6	0.2
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.6	3.0	0.4	0.8	-0.7	-0.5	-0.5	0.7	0.7	1.7	0.1	-0.7	-0.6
Friendships satisfaction	0.3	0.3	1.2	-0.1	-1.0	0.8	0.3	0.2	-0.4	-0.1	0.0	-0.1	0.8	1.1
Commuting to job workplace: Walk	0.3	0.4	1.1	0.4	0.5	-0.5	1.0	0.7	0.3	0.3	0.7	0.5	0.7	0.6
Medication: Gliclazide	0.3	0.3	1.6	-0.0	-0.3	0.7	1.3	0.8	-0.2	-0.1	0.3	0.1	0.4	0.7
Arm fat mass (left)	0.3	1.4	5.6	0.2	-0.1	2.4	1.5	1.3	0.5	-0.3	1.6	-0.7	1.5	0.3
Ever taken oral contraceptive pill	0.3	0.3	1.3	-0.7	0.0	-1.1	0.2	-0.2	-0.3	-0.5	0.9	-0.2	-0.1	0.0
Hearing aid user	0.3	0.3	0.8	0.4	-0.2	0.9	0.4	0.4	0.6	0.9	-0.0	0.3	-0.1	0.7
Medication: Paracetamol	0.3	0.4	1.3	-0.7	-0.3	-0.6	0.5	0.2	-0.9	-0.6	1.2	-0.7	0.7	0.3
Medication: Atorvastatin	0.3	0.3	0.6	-0.6	-0.5	-0.4	-0.7	-0.8	-0.4	-0.2	-0.8	-0.4	-0.6	-0.7
Basal metabolic rate	0.3	1.7	4.4	1.9	1.6	1.4	-0.9	-0.4	2.1	1.2	1.0	-0.0	-1.2	-1.2
Unable to work because of sickness or disability	0.3	0.4	1.0	-0.0	0.7	0.8	0.8	0.8	0.4	0.4	1.0	0.6	0.7	0.3
Impedance of whole body	0.3	1.7	6.0	-2.4	-1.7	-1.8	0.7	0.1	-1.8	-1.1	0.5	-0.2	0.8	0.5
Arm predicted mass (left)	0.3	1.6	4.2	1.9	1.6	1.0	-1.0	-0.5	2.0	1.3	0.5	0.2	-1.3	-1.2
Bipolar Disorder or Schizophrenia	0.2	0.5	1.5	0.4	0.5	-0.5	1.1	0.5	0.2	0.6	0.5	0.7	1.0	1.2
Depressed Affect (Nagel 2018)	0.2	0.4	1.8	0.3	0.5	0.8	0.5	0.3	0.7	0.2	-0.6	0.2	0.5	1.3
Schizophrenia (2018)	0.2	0.3	0.9	0.5	0.8	-0.6	0.3	-0.1	0.2	0.8	-0.6	0.6	0.2	0.9
Major Depression (MDD)	0.2	0.2	0.7	0.0	0.8	0.3	0.2	0.4	0.0	0.8	-0.3	0.0	0.1	0.8
Verbal and Numeric Reasoning (VNR)	0.2	0.4	1.3	-0.4	-0.9	0.1	1.0	0.6	0.0	-0.8	0.5	0.1	0.5	1.1
Prostate Cancer	0.2	0.3	0.8	-0.6	-0.4	-0.4	-0.4	-0.4	-0.5	-0.9	0.8	-0.8	-0.4	-0.3
Mean Putamen Volume	0.2	0.2	0.7	0.7	0.4	-0.5	-0.3	-0.1	0.5	0.1	-0.8	0.3	0.1	-0.7
Height	0.2	3.7	9.7	1.4	2.4	-0.7	-2.5	-1.7	1.8	2.1	1.7	1.1	-3.1	-1.3
Chronotype (morning person)	0.2	0.6	3.2	0.6	0.5	0.7	-0.6	-0.4	0.2	0.7	-1.8	0.5	-0.7	0.4
Hearing difficulty/problems: Yes	0.2	0.3	1.5	-0.1	0.3	0.8	0.4	0.2	0.2	0.4	-1.2	-0.1	-0.2	0.9
Angina	0.2	0.2	1.5	-0.1	0.2	0.6	0.0	0.3	0.2	0.1	0.3	0.4	1.2	0.2
Impedance of leg (right)	0.2	0.8	3.3	-0.5	0.4	-0.7	1.0	0.7	-0.2	1.1	0.4	1.8	0.9	1.2
Leg fat-free mass (left)	0.2	1.1	2.7	1.1	0.6	1.0	-1.1	-0.8	1.4	0.2	0.9	-0.9	-1.3	-1.6
Bilateral oophorectomy (both ovaries removed)	0.2	0.2	0.5	0.3	0.6	0.2	-0.6	-0.5	0.2	0.1	-0.5	-0.2	-0.7	-0.5
Impedance of leg (left)	0.2	1.2	3.5	-0.5	0.6	-0.7	1.4	1.0	-0.1	1.3	0.5	1.9	1.1	1.5
Leg predicted mass (left)	0.2	1.2	3.0	1.0	0.6	0.9	-1.2	-0.8	1.3	0.1	0.9	-1.0	-1.3	-1.7
Trunk fat mass	0.2	1.0	3.3	-0.0	0.0	1.8	1.4	1.1	0.7	-0.1	1.7	-0.7	1.2	-0.0
Had menopause	0.2	0.3	1.1	0.5	0.3	0.4	-0.0	0.1	1.1	0.3	-1.0	0.3	-0.0	0.8
Ever unenthusiastic/disinterested for a whole week	0.2	0.2	0.9	0.4	0.4	0.2	0.5	0.5	0.3	0.1	0.4	0.2	0.9	0.7
Alcohol intake versus 10 years previously	0.2	0.3	2.0	0.3	0.2	-0.2	0.7	0.5	0.1	0.2	1.4	0.3	0.5	0.1
Forced expiratory volume in 1-second (FEV1)	0.2	0.8	2.5	-0.3	-0.8	-1.3	-0.9	-0.9	-0.4	-0.5	-0.5	-0.9	-0.6	-1.6
Asthma	0.2	0.3	1.6	0.4	0.4	1.3	0.2	0.4	0.4	0.2	0.7	0.6	0.3	0.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.6	2.2	-0.4	-0.8	-1.5	-0.6	-0.7	-0.4	-0.5	-0.7	-0.8	-0.3	-1.1
Breastfed as a baby	0.2	0.2	0.6	0.1	-0.5	0.7	0.1	0.3	0.2	-0.1	-0.4	0.2	0.7	0.7
Hair/balding pattern: Pattern 4	0.2	0.5	1.6	-0.4	-0.6	0.7	1.1	0.5	-0.2	-0.6	-0.4	-0.6	1.3	0.5
Peak expiratory flow (PEF)	0.2	0.5	2.3	0.3	-0.2	-0.7	-0.7	-0.8	-0.4	-0.1	0.5	-0.7	-1.0	-1.5
Gout (self-reported)	0.2	0.2	1.0	0.0	-0.4	0.4	0.5	0.5	0.3	0.2	-0.3	0.2	1.0	0.5
Hypothyroidism/myxoedema (self-reported)	0.2	0.3	1.3	-0.3	-1.0	-0.1	-0.5	-0.5	0.1	-0.1	-1.1	-0.3	-0.5	-0.4
Medication: Ventolin 100micrograms inhaler	0.2	0.3	0.7	0.3	-0.1	0.8	0.4	0.4	0.2	0.3	0.7	0.8	0.5	0.5
Comparative body size at age 10	0.2	0.5	1.6	-0.2	-0.7	1.0	0.2	0.0	0.1	-1.3	-1.2	-1.0	0.0	-0.1
Number of full brothers	0.2	0.2	0.7	-0.5	0.5	-0.3	0.8	0.3	0.2	-0.0	0.7	-0.2	0.8	0.2
Mouth/teeth dental problems: Loose teeth	0.2	0.2	0.6	-0.1	-0.5	-0.2	0.1	0.4	0.3	-0.3	0.7	-0.4	0.8	-0.6
Neck or shoulder pain in last month	0.2	0.3	1.1	-0.3	0.1	0.5	0.7	0.6	0.0	-0.0	0.6	-0.1	1.0	0.9
Medication: Allopurinol	0.2	0.3	0.6	0.3	-0.1	0.6	0.7	0.6	0.3	0.6	-0.4	0.5	0.8	0.6
Medication: Omeprazole	0.2	0.3	1.3	-0.5	0.1	-0.7	-0.3	-0.2	-0.4	-0.6	0.1	-0.8	-0.0	-1.1
Mean time to correctly identify matches	0.2	0.3	1.6	-0.6	-1.3	-0.6	0.2	0.4	-0.0	-0.3	-0.1	-0.0	1.0	0.5
Number of full sisters	0.2	0.2	0.7	0.1	0.3	0.7	-0.6	-0.5	-0.3	0.2	-0.9	0.1	0.0	0.0
Leg fat-free mass (right)	0.2	1.1	2.2	1.2	0.8	0.9	-1.1	-0.7	1.5	0.4	0.9	-0.9	-1.3	-1.5
Average weekly red wine intake	0.2	0.3	0.9	0.5	0.5	0.4	0.2	0.4	1.0	0.7	1.0	0.8	0.2	-0.0
Ever had bowel cancer screening	0.2	0.2	1.0	0.4	0.5	1.0	-0.4	0.1	0.4	0.1	-0.2	-0.0	0.8	-0.3
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	0.9	0.1	0.4	0.2	-1.0	-0.7	0.3	0.3	-0.4	0.3	-0.6	-0.3
Osteoporosis (self-reported)	0.2	0.3	1.0	-0.5	-0.9	0.1	0.6	0.3	-0.5	-0.4	0.5	-0.4	1.0	0.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.4	1.6	-0.7	-1.3	-0.6	0.3	0.1	-0.6	-0.7	-0.5	-0.6	0.7	0.0
Leg predicted mass (right)	0.2	1.1	2.1	1.1	0.7	0.9	-1.0	-0.7	1.4	0.3	0.9	-0.9	-1.3	-1.4
Miserableness	0.2	0.3	0.7	0.4	0.4	0.7	0.7	0.5	0.2	0.3	-0.7	0.3	0.6	0.9
Wears glasses or contact lenses	0.2	0.2	0.8	0.2	0.4	-0.0	0.7	0.5	0.7	0.3	0.0	0.3	0.4	0.9
Commuting to job workplace: Public transport	0.2	0.2	1.2	0.6	0.3	-0.1	0.2	0.4	1.1	0.5	-0.1	0.7	0.2	-0.2
Medication: Lisinopril	0.2	0.3	1.5	-0.1	0.4	1.0	-0.2	-0.1	0.4	0.4	-1.2	0.2	-0.1	-0.4
Supplements: Calcium	0.2	0.2	0.5	0.7	0.4	-0.7	-0.3	-0.3	0.1	0.6	0.3	0.4	-0.1	0.1
Heart disease (siblings)	0.2	0.3	0.9	-0.3	0.0	-0.3	0.4	0.4	-0.7	-0.6	0.2	-0.4	0.9	0.5
Pack years of smoking	0.2	0.2	0.9	0.3	0.8	0.3	0.5	0.3	0.2	0.5	1.0	0.2	0.2	-0.0
Intelligence (Savage-Jansen 2018)	0.1	0.2	1.3	0.1	-0.3	-0.1	-0.0	-0.1	-0.1	-0.4	1.1	-0.2	-0.6	0.4
Neuroticism (2016)	0.1	0.2	0.5	-0.4	-0.2	-0.1	0.4	0.0	0.3	-0.3	0.7	-0.2	0.4	0.6
Blood Red Count	0.1	1.2	4.9	0.8	0.8	2.2	-0.0	0.6	0.5	1.0	1.9	0.8	1.0	0.2
Hypothyroidism (self reported)	0.1	0.2	0.7	0.6	-0.3	0.7	-0.2	0.0	0.8	0.6	-0.6	0.5	-0.2	0.0
Respiratory disease	0.1	0.2	0.8	-0.4	-0.1	-0.2	-0.8	-0.5	-0.9	-0.6	-0.1	-0.1	-0.5	-0.3
Other serious medical condition/disability diagnosed by doctor	0.1	0.1	0.3	0.0	-0.4	0.2	0.2	0.2	0.0	-0.3	-0.5	-0.5	0.4	0.4
Ever used hormone-replacement therapy (HRT)	0.1	0.1	0.4	-0.4	0.1	-0.0	-0.4	-0.4	-0.4	-0.5	0.1	-0.5	-0.1	-0.6
Medication: Co-codamol	0.1	0.1	0.4	-0.0	0.1	0.5	0.4	0.4	0.5	0.3	0.6	0.4	0.1	0.1
Pack years adult smoking proportion	0.1	0.2	0.8	0.2	0.8	0.2	0.4	0.3	0.0	0.4	0.9	0.0	0.2	-0.3
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.5	0.1	0.0	-0.5	-0.7	-0.5	-0.5	0.2	-0.3	-0.3	-0.4	-0.1
Medication: Levothyroxine sodium	0.1	0.1	0.9	-0.2	-0.7	-0.1	-0.0	-0.1	0.0	-0.1	-1.0	0.0	-0.1	0.0
High blood pressure (mother)	0.1	0.1	0.6	0.0	-0.8	-0.4	0.2	0.0	0.1	0.1	-0.2	-0.2	0.3	0.1
Hearing difficulty/problems with background noise	0.1	0.1	0.7	0.1	0.2	0.8	0.1	0.2	0.6	0.5	-0.0	0.1	0.2	0.4
Forced vital capacity (FVC)	0.1	0.3	1.6	0.3	-0.1	-0.6	-0.7	-0.5	0.5	0.1	-0.2	-0.3	0.1	-1.2
Hayfever/allergic rhinitis (self-reported)	0.1	0.1	0.5	-0.1	-0.5	0.3	-0.5	-0.3	-0.7	-0.2	0.3	-0.2	-0.1	-0.3
Fluid intelligence score	0.1	0.2	0.7	-0.2	-0.6	0.0	0.1	-0.2	-0.1	-0.4	0.8	-0.0	-0.8	-0.1
Qualifications: A levels/AS levels or equivalent	0.1	0.2	0.4	0.7	-0.1	0.3	-0.5	-0.3	0.3	0.4	-0.6	0.4	-0.4	0.3
Qualifications: O levels/GCSEs or equivalent	0.1	0.2	1.0	-0.0	-0.3	0.2	-0.5	-0.3	0.2	0.2	0.8	-0.1	-1.0	-0.3
Forced vital capacity (FVC), Best measure	0.1	0.4	1.7	0.0	-0.3	-1.1	-0.7	-0.5	0.5	-0.0	-0.5	-0.4	-0.0	-1.3
Age at first live birth	0.1	0.2	0.7	0.4	-0.1	-0.2	-0.4	-0.1	0.6	0.7	-0.5	0.8	-0.4	-0.5
Qualifications: College or University degree	0.1	0.2	1.0	0.2	-0.5	-1.0	-0.3	-0.2	0.3	0.1	-0.5	0.4	-0.8	-0.0
Breast cancer (self-reported)	0.1	0.1	0.3	-0.2	-0.0	-0.1	0.5	0.4	-0.0	-0.2	-0.3	0.0	0.3	-0.6
High cholesterol (Self-reported)	0.1	0.2	1.4	-0.3	-0.3	0.7	-0.0	0.1	-0.1	-0.1	-0.7	-0.0	1.2	-0.3
Number of operations (self-reported)	0.1	0.1	0.2	-0.4	-0.4	0.5	-0.4	-0.3	0.2	-0.3	-0.2	-0.4	0.0	-0.2
Risk taking	0.1	0.2	0.6	0.0	-0.5	-0.6	0.2	-0.0	-0.1	-0.2	0.8	-0.5	0.3	0.2
Commuting to job workplace: Cycle	0.1	0.2	0.7	0.6	0.2	0.8	-0.2	0.1	-0.1	0.1	0.1	0.6	-0.3	0.6
Medication: Omeprazole (e.g. Zanprol)	0.1	0.1	0.6	0.3	0.5	-0.3	-0.3	-0.1	0.2	0.2	0.1	0.1	-0.1	-0.8
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Hair Pigment	0.0	0.8	1.9	-1.2	-0.7	-0.9	-0.8	-0.8	-1.4	-0.8	0.2	-0.7	-0.7	-1.1
Tanning	0.0	0.5	1.1	-0.5	-0.5	-1.0	-0.6	-0.9	0.2	-0.5	-0.7	-0.9	-1.1	-0.4
Asthma (self-reported)	0.0	0.1	0.6	-0.1	-0.2	0.8	-0.1	-0.1	-0.1	-0.2	0.6	0.2	-0.1	-0.0
Alcohol drinker status: Previous	0.0	0.1	0.2	-0.2	-0.1	-0.2	0.1	-0.1	-0.4	-0.3	0.1	-0.1	0.0	-0.5

Hub : Genes

DPH1

Models

Trait associations