Hub : Genes

DRD4

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Brain Putamen basal ganglia	0.3060	0.1110	3.8e-03	0.070	NA	0.021	NA	0.066	9.7e-03	NA	1.1e-01	NA	1.2e-02
2	GTEx	Esophagus Mucosa	0.0920	0.0360	2.1e-03	0.022	NA	0.050	NA	0.054	1.2e-02	NA	2.8e-04	NA	1.7e-04
3	METSIM	Adipose	0.0893	0.0259	8.3e-06	0.078	0.051	0.050	0.06	0.068	1.0e-11	4.2e-08	5.1e-08	2.3e-09	2.0e-10
4	YFS	Blood	0.1142	0.0276	5.9e-13	0.021	0.048	0.051	NA	0.031	1.2e-07	2.5e-15	2.7e-16	NA	2.0e-10
5	TCGA	Breast Invasive Carcinoma	0.0276	0.0160	2.3e-03	0.008	0.013	0.008	NA	0.010	6.8e-03	9.0e-04	6.7e-03	NA	3.3e-03
6	TCGA	Kidney Renal Clear Cell Carcinoma	0.0724	0.0364	5.0e-04	0.016	0.029	0.026	NA	0.025	6.2e-03	3.0e-04	5.3e-04	NA	7.7e-04
7	TCGA	Brain Lower Grade Glioma	0.0478	0.0279	9.3e-03	0.036	0.009	0.020	NA	0.025	5.9e-05	2.6e-02	2.2e-03	NA	7.2e-04
8	TCGA	Pancreatic Adenocarcinoma	0.1800	0.0800	4.1e-03	0.022	0.036	0.068	NA	0.045	4.1e-02	1.2e-02	8.6e-04	NA	5.7e-03
9	TCGA	Thyroid Carcinoma	0.0930	0.0480	6.9e-04	-0.003	0.033	0.015	NA	0.000	8.4e-01	3.4e-04	1.1e-02	NA	2.9e-01

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	1.1	1.7	3.9	1.6	0.0	1.2	0.7	2.0	1.0	1.4	-0.1	2.0
Bipolar Disorder or Schizophrenia	0.4	1.0	2.1	0.2	0.8	-0.9	1.4	-1.1	-0.7	-1.3	-1.2	-0.5
Depressed Affect (Nagel 2018)	0.3	0.6	1.3	-0.4	0.9	0.9	1.1	-1.0	0.6	-0.2	-0.7	0.8
Depression (Nagel 2018)	0.3	0.5	1.5	1.2	1.1	0.1	0.6	-1.0	0.3	-0.1	-0.2	0.3
Intelligence (Savage-Jansen 2018)	0.4	1.3	3.9	1.3	2.0	-0.7	0.8	-1.5	0.5	-1.2	-0.8	0.6
Neuroticism (Nagel 2018)	0.2	0.4	1.4	0.3	-0.1	1.1	0.3	-0.5	0.3	-0.2	-1.2	0.7
Schizophrenia (2018)	1.8	3.7	9.0	-0.9	0.9	-1.9	1.1	-3.0	-1.7	-2.7	-1.5	-2.3
Schizophrenia vs Biploar Disorder	1.3	1.7	4.9	-0.3	0.0	0.0	-1.0	-1.1	-2.0	-2.2	-0.8	-2.0
Worry (Nagel 2018)	0.4	0.8	1.9	-1.1	-1.0	-0.3	-1.3	-0.3	-0.9	-0.6	-1.4	-0.6
Alzheimer’s Disease (in mother)	0.4	0.5	2.5	0.1	-0.0	-0.9	-0.5	-0.8	-0.4	-1.6	-0.4	-0.0
Alzheimer’s Disease (in father)	0.3	0.3	0.9	-0.8	-0.8	0.2	0.2	0.5	-0.6	-0.4	-0.9	0.2
Alzheimer’s Disease (including proxy)	0.4	0.5	2.5	-0.7	-0.7	-0.5	-0.5	-0.4	-0.5	-1.6	-0.6	0.1
Crohns Disease (2017)	0.5	1.1	3.9	-0.5	0.9	-1.5	0.9	-1.0	0.8	-0.0	2.0	-0.3
Irritable Bowel Disease (IBD)	0.8	1.8	6.2	-2.0	0.3	-2.1	0.8	-0.4	0.7	0.4	2.5	-0.5
Ulcerative Colitis (UC)	1.0	1.8	9.4	-3.1	-0.4	-1.9	0.3	0.2	-0.2	0.6	1.3	-0.8
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Reaction Time	0.4	0.7	2.1	-0.3	-0.6	1.1	-0.7	1.1	0.6	0.8	-0.3	1.5
Verbal and Numeric Reasoning (VNR)	0.3	0.8	1.7	1.3	0.9	-0.7	1.2	-0.1	0.4	-1.1	-0.4	1.1
Breast Cancer	1.8	4.4	21.7	4.7	0.2	-0.2	2.6	-1.9	0.1	-0.5	-2.6	0.4
Ovarian Cancer	0.7	1.0	2.6	-1.3	0.6	-1.3	0.3	-1.6	-0.6	-0.5	-0.5	-1.2
Prostate Cancer	0.6	0.8	2.7	0.2	-1.6	0.3	-0.6	1.3	0.2	0.1	1.3	0.6
Age at First Birth	1.5	2.2	8.9	-3.0	-0.6	-0.4	0.1	-0.3	-1.8	-1.3	0.7	-2.2
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	1.2	1.6	5.3	-0.2	1.4	-1.1	1.3	-0.1	1.9	-0.0	0.8	2.3
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Crohns Disease (2012)	0.6	1.0	5.5	0.4	0.4	-0.0	1.2	-0.4	0.7	0.6	2.3	-0.7
Mean Putamen Volume	1.1	1.3	3.2	-1.0	-0.9	-0.8	-0.9	-0.5	-1.1	-1.8	0.8	-1.7
Fasting Glucose	1.1	1.3	3.8	-1.3	1.1	-2.0	1.2	-1.2	0.6	-0.7	0.8	0.3
HbA1C	4.9	5.5	9.8	2.6	1.3	2.7	2.8	0.6	3.1	2.0	1.3	3.1
HDL Cholesterol	1.3	2.2	6.3	-0.1	-2.5	2.1	-1.4	2.2	-0.8	1.1	-0.7	0.0
LDL Cholesterol	0.5	0.9	3.2	0.8	0.4	-0.3	-0.1	-0.8	-1.3	-1.8	-0.3	-1.1
Lupus	7.1	10.7	37.8	-0.8	6.1	-1.2	3.4	-5.6	2.6	-1.0	-1.6	1.9
Neuroticism (2016)	1.8	2.6	7.5	-2.7	-1.2	0.6	-1.4	0.2	-2.5	-0.4	-1.3	-2.1
Primary Biliary Cirrhosis	1.7	2.5	7.0	-0.3	2.6	-0.0	1.7	-1.8	2.2	0.1	-0.7	1.9
Rheumatoid Arthritis	0.6	0.8	2.8	-0.0	1.1	-0.1	1.0	-1.7	1.1	1.2	-0.4	0.1
Schizophrenia (2014)	0.7	1.6	5.2	0.1	0.7	-1.4	0.6	-0.8	-1.8	-2.3	-0.4	-1.6
Triglycerides	1.1	1.8	5.0	1.2	2.2	-1.1	1.6	-1.8	1.5	0.5	0.9	0.0
Type 2 Diabetes (T2D) (2012)	1.1	1.2	6.4	0.0	0.0	0.0	0.0	-0.8	1.8	0.8	2.5	0.4
Ulcerative Colitis	1.4	2.1	4.3	-1.9	-1.2	-1.5	0.4	1.8	-1.2	-1.5	2.1	-0.7
Blood Eosinophil Count	0.3	2.1	5.6	1.6	2.3	-0.5	1.6	-2.4	0.2	-1.4	-0.7	-0.2
Blood Platelet Count	0.8	9.4	49.3	0.1	-1.9	-0.8	-7.0	2.1	2.2	1.8	4.0	1.7
Blood Red Count	0.1	1.4	4.0	-1.7	0.3	-0.4	0.7	1.6	0.9	2.0	1.1	0.8
Blood White Count	0.1	0.8	2.8	-0.6	1.0	0.6	1.1	-0.1	0.8	-0.2	-1.0	1.7
Heel T-Score	0.1	0.5	1.3	0.5	1.1	-0.0	1.1	0.5	0.7	0.8	0.8	0.5
BMI	0.4	2.3	11.1	-3.3	0.4	-0.7	1.6	-0.1	1.3	0.6	1.8	1.0
Height	0.3	5.6	16.7	1.6	3.8	-0.3	4.1	-2.9	1.5	-1.1	-1.7	1.5
Waist Hip Ratio (WHR)	1.3	5.9	32.7	5.7	1.6	-2.6	1.5	-2.2	-0.1	-1.9	-0.8	-0.3
Systolic Blood Pressure	0.4	1.9	6.0	-1.9	-1.4	-0.1	-2.5	-0.4	-1.5	-0.3	-1.1	-1.4
Smoking Status	0.6	1.4	5.6	1.0	-2.4	1.8	-1.3	0.4	0.0	0.5	-0.7	-0.4
Allergy or Eczema	1.4	3.8	7.5	-2.0	-0.3	0.4	0.1	-2.0	-2.7	-2.7	-2.1	-2.6
Cardiovascular Disease	0.9	3.0	9.2	-1.9	0.2	-1.2	-0.1	-3.0	-1.6	-1.0	-2.3	-2.1
Hypothyroidism (self reported)	3.8	8.8	32.9	-0.4	5.7	-1.5	3.3	-3.3	3.8	0.5	1.4	2.2
Respiratory disease	0.7	1.6	5.6	-1.1	0.0	-0.6	-0.6	0.5	-2.3	-1.0	-0.5	-2.4
Type 2 Diabetes (T2D) (2018)	0.4	0.7	2.0	0.9	-1.4	-0.2	-1.2	-0.1	-0.9	-0.6	0.3	-1.0
Lung FEV1/FVC ratio	0.3	1.6	7.0	-2.6	-1.9	0.8	-0.4	1.3	-0.0	0.9	0.7	0.5
Lung FVC	0.3	1.8	5.9	-1.1	2.4	0.6	1.0	-1.9	1.3	1.0	-1.0	0.6
Neuroticism	0.4	0.9	2.6	-1.0	-0.2	0.2	-1.2	-0.2	-0.9	-1.4	-1.6	0.0
Chronotype (morning person)	0.5	1.0	4.1	-0.4	2.0	0.1	1.7	-0.2	1.1	0.5	0.2	1.0
Hair Pigment	0.0	1.2	3.6	-0.9	0.9	1.2	0.4	-1.9	1.6	1.3	0.3	0.3
Tanning	0.0	0.2	0.7	-0.5	-0.4	-0.6	0.1	-0.2	0.2	0.8	0.0	-0.6
Hand grip strength (left)	1.1	2.9	11.3	0.6	1.7	-0.8	3.4	-1.3	2.3	1.0	0.2	1.7
Number of treatments/medications taken	0.5	1.0	3.3	-0.6	1.6	-1.1	0.2	-1.8	0.1	-0.4	-0.9	0.1
Average weekly spirits intake	0.4	0.5	1.4	1.2	1.0	0.6	-0.3	-0.8	0.9	0.2	-0.2	0.2
Sensitivity / hurt feelings	0.3	0.5	1.2	0.3	-0.6	0.1	0.7	1.0	0.6	0.9	-0.4	1.1
Frequency of depressed mood in last 2 weeks	0.2	0.3	1.3	-0.2	1.2	-0.1	-0.5	-0.9	0.2	0.7	-0.2	0.1
Hearing difficulty/problems: Yes	0.5	0.8	2.4	-0.9	-0.4	-1.2	0.7	-0.4	1.0	-0.6	1.6	0.7
Relative age of first facial hair	0.3	0.7	3.4	1.8	0.1	0.7	0.4	-0.5	0.8	0.6	-0.7	0.8
Other serious medical condition/disability diagnosed by doctor	1.3	1.6	4.0	-1.5	-0.6	-1.2	0.3	-0.3	-1.6	-1.6	1.3	-2.0
Ever used hormone-replacement therapy (HRT)	1.1	1.4	3.9	-1.4	0.6	-0.6	0.3	-2.0	-0.8	-1.6	-1.1	-1.0
Ever had hysterectomy (womb removed)	1.3	1.5	4.1	-1.7	0.2	-0.3	-1.4	-1.5	-1.0	0.2	-2.0	-1.0
Systolic blood pressure, automated reading	0.3	0.8	2.1	-1.4	0.2	1.2	-0.5	-0.9	0.7	1.3	-0.4	0.3
Eye problems/disorders: Diabetes related eye disease	0.4	0.4	1.2	1.0	-1.1	0.3	0.5	0.3	-0.5	0.2	0.7	-0.8
Angina	1.1	1.5	5.0	1.8	1.1	-1.1	2.2	-1.3	1.0	0.4	-0.1	0.2
Medication for hormone replacement therapy	0.5	0.6	1.3	-0.9	-0.5	-0.6	-0.9	-0.5	-0.8	-1.1	-0.3	-0.8
Vitamin and mineral supplements	0.6	0.8	3.6	1.9	-0.8	0.6	-0.3	1.2	-0.5	-0.3	0.4	-0.4
Supplements: Zinc	1.0	1.1	3.1	-1.0	-1.1	0.7	-1.6	0.3	-0.7	-0.7	-1.8	0.4
Medication: Co-codamol	1.4	1.7	3.4	-0.9	-0.2	-0.7	-1.6	-1.2	-1.6	-1.9	-1.8	-0.8
Medication: Metformin	0.1	0.2	0.5	0.5	-0.2	0.4	0.7	-0.5	-0.3	0.1	-0.1	-0.6
Diabetes (father)	1.4	1.8	3.7	0.4	1.4	1.2	1.0	1.2	1.6	1.9	0.6	1.9
Diabetes (mother)	1.1	1.4	3.1	-0.6	1.5	-1.6	1.8	-0.7	-0.7	-1.7	0.2	-0.4
Severe depression (siblings)	0.4	0.4	1.5	-0.3	-1.2	0.5	-1.0	0.2	-0.3	-0.2	0.6	-0.6
Pack years adult smoking proportion	1.6	2.4	8.4	-1.0	-0.1	2.9	1.2	1.4	1.6	1.7	1.0	1.5
Impedance of leg (right)	0.6	2.9	14.9	3.9	1.3	-0.7	1.2	-1.1	-0.6	-1.1	0.9	-1.9
Leg fat-free mass (left)	0.3	1.6	4.1	-2.0	0.2	0.2	2.0	-0.1	1.5	0.8	0.1	1.9
Trunk fat percentage	0.3	1.3	3.5	-1.3	0.4	-1.2	1.9	-1.4	-0.8	-1.3	-0.5	-0.8
Hand grip strength (right)	1.4	3.8	14.6	0.4	2.7	-0.4	3.8	-1.5	2.4	1.1	-0.1	1.7
Townsend deprivation index at recruitment	0.8	1.1	4.2	0.0	-1.4	0.6	-2.1	0.9	-1.2	0.0	0.2	-1.0
Current tobacco smoking	0.9	1.4	6.9	0.3	-2.6	0.6	-1.3	0.8	-0.8	0.2	-0.1	-1.5
Average weekly fortified wine intake	1.2	1.4	3.7	-0.5	-0.4	-1.6	-0.9	-1.2	-1.3	-1.4	-0.0	-1.9
Maternal smoking around birth	1.5	2.2	7.2	-0.9	-1.2	-0.6	-1.3	-0.3	-2.7	-1.6	-1.9	-1.4
Fed-up feelings	0.6	1.1	5.0	0.0	0.7	1.2	-0.1	-1.4	0.1	0.1	-2.2	0.7
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.2	0.7	-0.2	0.3	0.4	0.8	-0.9	0.2	0.3	-0.3	-0.2
Relative age voice broke	1.0	1.6	5.1	0.1	-1.3	0.5	-0.1	0.1	-2.3	-1.5	-1.7	-1.5
Taking other prescription medications	2.0	3.1	7.7	-2.5	1.2	-1.6	0.8	-2.8	-1.2	-1.8	-1.0	-1.9
Age when periods started (menarche)	0.3	0.8	3.4	1.1	-0.5	0.1	-1.9	1.4	-0.2	0.7	0.3	0.3
Bilateral oophorectomy (both ovaries removed)	1.2	1.4	3.1	-0.7	1.1	-1.5	-1.4	-1.6	-0.4	-0.5	-1.8	-0.6
Heel bone mineral density (BMD) T-score, automated (left)	0.4	1.0	3.6	1.3	1.9	-1.3	0.0	-1.1	0.3	-0.2	-0.7	0.5
Tinnitus: Yes, but not now, but have in the past	2.0	2.2	6.9	-1.2	-0.1	-2.6	-0.5	-0.2	-1.9	-1.9	-0.1	-1.8
Qualifications: CSEs or equivalent	0.4	0.5	1.2	0.2	0.6	0.7	1.1	0.5	0.8	-0.2	1.0	0.9
Serious illness, injury or assault to yourself	1.1	1.4	4.3	-2.0	0.5	-2.1	0.7	0.3	-0.2	-0.5	1.6	-0.4
High blood pressure	0.6	1.6	4.0	-1.4	0.6	-1.3	-1.2	-2.0	-0.9	0.1	-1.8	-1.0
Hayfever, allergic rhinitis or eczema	1.0	2.3	4.9	-1.3	-0.6	1.0	-0.9	-1.1	-2.2	-1.8	-1.6	-2.2
Multivitamins +/- minerals	0.9	1.1	4.0	-2.0	0.9	-0.1	0.7	-1.1	0.8	0.7	-1.3	0.9
Stomach or abdominal pain in last month	1.8	2.2	4.8	-2.2	0.1	-1.6	-1.5	-1.7	-1.2	-0.9	-0.7	-2.1
Supplements: Glucosamine	1.0	1.3	3.1	-0.3	1.6	0.3	-0.7	-0.8	1.5	1.4	-0.4	1.8
Diverticular disease/diverticulitis (self-reported)	0.9	1.0	4.9	0.7	1.1	-0.7	0.6	-2.2	-0.1	-0.4	-1.0	-0.8
Medication: Atenolol	1.4	1.7	4.7	1.3	0.8	0.2	2.2	-0.8	1.8	1.1	-0.4	1.7
Medication: Levothyroxine sodium	2.6	4.3	20.3	-0.1	4.5	-0.2	1.9	-2.0	2.3	-0.1	-0.2	2.4
Sitting height	1.1	7.9	22.8	0.0	4.8	0.0	4.2	-3.3	3.6	0.8	0.1	2.5
Chronic bronchitis/emphysema (father)	2.4	2.8	8.2	2.3	1.1	2.1	0.3	-0.0	2.1	1.1	-0.5	2.9
High blood pressure (mother)	0.5	0.7	2.8	-1.7	0.6	0.9	0.2	-0.8	0.0	-1.3	0.3	0.2
Body mass index (BMI)	0.3	1.5	10.0	-3.2	-0.4	-1.0	1.3	-0.4	0.1	-0.0	0.1	0.4
Impedance of leg (left)	0.6	3.1	11.9	3.5	1.6	-1.2	1.2	-1.5	-0.8	-1.5	0.6	-2.2
Leg predicted mass (left)	0.3	1.6	4.0	-2.0	0.2	0.1	2.0	-0.0	1.5	0.8	0.3	1.9
Trunk fat mass	0.3	1.4	5.6	-1.6	0.6	-1.1	2.4	-1.4	-0.1	-0.8	-0.4	-0.1
Waist circumference	0.3	1.1	3.1	-1.0	0.4	-1.8	1.5	-1.2	-0.4	-1.1	0.0	-0.3
Number of incorrect matches in round	0.2	0.4	1.1	0.8	0.9	0.0	0.1	-0.3	0.5	-0.6	-0.5	1.1
Past tobacco smoking	0.6	1.2	3.0	-1.6	0.5	-1.1	-0.2	0.6	-1.5	-1.7	0.4	-1.0
Alcohol usually taken with meals	1.6	2.5	7.1	1.7	1.2	-0.7	2.4	-0.2	1.8	1.2	2.7	0.2
Nervous feelings	0.2	0.4	2.5	0.0	0.3	0.5	-0.5	-0.3	0.0	0.2	-1.6	0.4
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	1.2	-0.4	-0.2	0.5	-0.7	0.8	0.1	1.1	-0.0	0.3
Hearing difficulty/problems with background noise	0.3	0.4	2.0	-1.4	-1.0	0.1	-0.7	-0.6	0.2	-0.0	-0.2	-0.3
Hair/balding pattern: Pattern 2	0.7	0.9	4.2	-0.1	-0.4	1.2	2.0	-0.8	1.1	0.2	0.8	-0.1
Had menopause	1.4	1.7	3.9	-1.7	-0.9	-1.2	-1.0	-1.3	-1.6	-0.8	-0.7	-2.0
Had other major operations	0.9	1.1	2.3	0.2	1.2	0.5	1.4	-1.3	0.6	-0.3	-1.5	1.2
Forced vital capacity (FVC)	0.7	2.5	5.3	-0.8	2.3	1.3	2.3	-1.7	2.1	1.4	0.3	0.8
Heel bone mineral density (BMD) T-score, automated (right)	0.4	0.9	3.8	0.8	1.9	-1.2	0.7	-1.2	0.1	-0.6	-0.6	0.5
Ever unenthusiastic/disinterested for a whole week	3.2	3.9	8.8	1.3	3.0	0.9	2.1	-1.9	2.7	2.2	-0.1	1.8
Qualifications: None of the above	0.2	0.4	1.2	0.6	0.4	-1.1	0.2	0.1	0.3	0.4	1.0	-0.4
Financial difficulties in last 2 years	0.1	0.2	0.8	0.1	-0.4	0.2	-0.9	0.5	0.1	0.1	0.2	0.4
Mouth/teeth dental problems	0.7	1.1	2.7	-0.9	0.2	1.2	-1.4	-1.0	-0.6	-1.2	-1.6	-0.1
Heart attack	1.1	1.4	4.6	2.1	0.8	0.5	1.2	0.6	1.3	1.4	0.7	1.1
Allergy	0.7	1.6	3.6	1.2	-0.0	-0.8	0.8	1.0	1.8	0.9	1.6	1.9
Pain all over the body in last month	0.2	0.2	0.8	0.2	0.4	-0.9	0.5	-0.6	-0.3	-0.5	-0.0	-0.3
Diabetes (self-reported)	0.3	0.5	1.9	0.5	-1.4	0.1	-0.9	0.0	-0.7	-0.4	0.2	-0.7
Hayfever/allergic rhinitis (self-reported)	2.3	3.1	6.7	-1.5	-1.6	0.2	-1.4	-0.9	-2.6	-2.3	-1.2	-2.6
Medication: Ramipril	1.6	2.0	11.6	-1.6	-0.0	0.8	-1.0	-1.1	-0.5	-0.1	-3.4	0.8
Medication: Simvastatin	0.4	0.6	1.8	1.0	0.2	-0.8	-0.4	-0.6	-0.6	-1.2	-1.3	0.2
Fluid intelligence score	0.4	0.9	2.2	0.7	1.4	-0.4	1.5	-0.9	0.8	-1.1	-0.3	0.9
Illnesses of siblings	0.6	0.8	5.4	0.3	0.1	0.4	1.0	0.2	0.8	0.1	2.3	-0.5
Neuroticism score	0.2	0.5	1.2	-0.9	0.7	-0.5	-0.2	-1.0	0.3	-0.2	-1.1	0.6
Weight	0.3	1.7	6.4	-2.4	0.6	-0.8	2.5	-1.1	0.8	-0.0	0.0	0.9
Impedance of arm (right)	0.3	1.2	4.3	2.1	0.4	0.2	-0.7	-0.3	-1.3	-1.0	-0.5	-1.6
Arm fat percentage (right)	0.2	0.8	4.4	-2.1	-0.4	-0.9	1.0	-0.6	-0.5	-0.6	-0.3	-0.1
Trunk fat-free mass	0.4	2.1	5.9	-1.2	0.8	-0.5	2.4	-0.5	2.2	0.8	1.2	2.0
Hip circumference	0.5	2.2	15.7	-4.0	-0.2	0.4	1.8	-0.6	-0.2	-0.5	-0.2	0.1
Time employed in main current job	2.0	2.4	13.5	-0.4	1.1	0.9	-1.2	-1.8	-0.1	0.1	-3.7	1.0
Alcohol intake versus 10 years previously	0.6	0.8	2.2	-0.5	-1.5	0.3	-1.4	0.3	-0.5	1.2	-0.2	-1.0
Father’s age at death	1.3	1.8	4.3	0.4	-1.6	-0.6	-0.1	1.3	-1.8	-2.1	1.2	-1.5
Worrier / anxious feelings	0.2	0.4	1.8	-0.5	-0.8	-0.4	-0.8	0.3	0.1	1.3	-0.5	-0.1
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.2	0.6	-0.8	0.2	-0.2	-0.6	0.5	-0.4	-0.0	0.3	0.2
Falls in the last year	0.6	0.7	1.4	1.0	-1.1	-0.8	-0.1	0.9	-1.2	-1.0	0.7	-0.3
Hair/balding pattern: Pattern 3	0.8	1.1	3.2	0.2	-0.6	0.2	-1.8	1.8	-1.4	-0.5	-1.1	0.4
Number of live births	0.6	0.8	3.3	0.7	-1.1	-0.7	0.1	-1.1	-0.5	0.7	-0.3	-1.8
Forced expiratory volume in 1-second (FEV1)	0.6	2.0	4.7	-2.2	1.6	1.1	1.5	-1.1	1.7	1.5	0.4	0.8
Pulse rate	0.2	0.3	1.5	-1.2	-0.2	-0.1	0.1	-0.4	-0.5	-0.5	-0.0	-0.4
Happiness	0.9	1.1	3.8	-1.3	0.3	0.3	2.0	-1.8	0.6	0.7	-0.2	-0.4
Noisy workplace	1.0	1.2	4.2	-1.7	0.3	1.4	-0.4	-0.0	0.8	2.0	-0.7	0.4
Qualifications: A levels/AS levels or equivalent	0.2	0.4	2.1	-0.1	-0.0	0.4	0.2	-0.8	-0.5	-0.1	-1.4	-0.5
Serious illness, injury or assault of a close relative in last 2 years	1.7	1.9	6.8	-2.6	-0.5	0.3	-2.0	0.2	-1.6	-0.6	-0.8	-1.6
Mouth/teeth dental problems: Dentures	0.6	1.1	3.8	-0.2	-0.1	-1.1	1.2	0.0	0.9	1.5	1.9	-0.6
Asthma	1.1	2.1	6.5	-1.6	0.1	-1.0	-0.5	-0.7	-2.2	-1.5	-1.1	-2.5
Medication: Ibuprofen (e.g. Nurofen)	2.5	3.1	13.1	1.1	1.8	0.2	0.9	1.0	2.4	1.3	1.0	3.6
Medication: Cholesterol lowering	0.5	0.8	3.1	1.4	-0.0	-0.4	0.7	-0.7	-0.9	-0.2	-1.8	-0.4
Depression (self-reported)	0.8	1.0	4.3	-0.6	0.4	0.8	0.7	-1.2	0.9	2.1	-0.0	-0.9
Medication: Lansoprazole	1.1	1.3	3.8	-1.1	1.1	-1.0	1.9	-1.9	0.4	-0.8	0.5	-0.1
Prospective memory result	0.6	0.7	3.4	-1.8	-0.8	0.3	-1.3	0.2	-0.7	0.1	0.3	-0.6
Lung cancer (father)	2.1	2.5	8.0	0.8	-2.8	-0.2	-2.3	1.0	-2.0	-0.5	-1.4	-1.2
Illnesses of mother	0.5	0.6	2.2	1.5	-0.7	-0.7	0.6	0.7	0.5	1.1	0.2	0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.7	4.6	-2.1	1.3	1.6	1.4	-0.7	1.1	1.5	-0.1	0.4
Pulse wave Arterial Stiffness index	0.7	0.8	2.3	0.5	1.1	-0.4	-0.7	-0.6	-1.2	-1.5	-0.6	-0.7
Impedance of arm (left)	0.4	1.9	6.4	2.5	-0.2	0.2	-1.2	0.1	-1.9	-1.0	-0.6	-2.1
Arm fat mass (right)	0.3	1.2	6.2	-2.5	0.0	-0.8	1.7	-0.9	0.3	-0.0	-0.1	0.5
Trunk predicted mass	0.4	2.3	6.1	-1.2	0.8	-0.4	2.5	-0.4	2.3	0.9	1.3	2.1
Standing height	0.3	2.9	10.1	1.5	2.6	0.0	3.2	-1.8	1.7	0.0	0.0	1.0
Length of working week for main job	1.6	1.8	7.4	-0.1	1.2	0.6	-0.2	0.8	1.9	1.5	-0.8	2.7
Exposure to tobacco smoke at home	0.6	0.7	2.8	-0.3	-1.0	-1.2	0.4	0.7	0.2	-0.5	1.7	-0.1
Breastfed as a baby	2.4	3.0	16.4	0.8	0.6	-4.0	-0.4	-2.0	-0.8	-1.4	0.2	-1.5
Tense / ‘highly strung’	0.9	1.6	5.1	-1.2	-0.9	-0.4	-2.2	-0.7	-1.0	-0.3	-2.2	-0.3
Seen doctor (GP) for nerves, anxiety, tension or depression	1.0	1.6	3.1	-1.4	0.6	-0.7	1.2	-1.8	1.2	1.6	1.3	-0.9
Hair/balding pattern: Pattern 4	0.3	0.7	2.6	-0.1	0.9	-1.5	0.0	-1.6	0.7	0.3	-0.5	0.0
Birth weight of first child	0.6	1.1	3.0	-0.6	1.7	0.3	1.0	-1.7	0.5	-0.5	-1.2	0.6
Peak expiratory flow (PEF)	1.3	3.1	8.6	-0.8	2.4	0.8	2.9	0.1	2.1	1.9	1.1	1.7
Pulse wave reflection index	1.1	1.3	2.9	-0.6	1.6	-0.1	0.1	-1.7	-0.9	-1.4	-1.5	-0.8
Ever highly irritable/argumentative for 2 days	0.7	0.8	1.8	-1.0	-0.0	0.9	1.1	-0.3	1.2	1.3	-0.0	1.0
Loud music exposure frequency	0.5	0.6	2.8	0.2	0.4	-0.6	0.3	-1.7	1.1	-0.0	0.2	0.5
Qualifications: O levels/GCSEs or equivalent	1.8	2.8	7.4	-2.6	-0.3	-0.9	-1.0	-0.3	-2.2	-2.7	-1.7	-1.2
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	1.5	1.2	0.0	-0.4	0.4	0.8	-0.3	0.7	0.8	-0.2
Blood clot in the leg (DVT)	0.8	1.0	3.5	0.8	-0.3	0.4	0.7	0.2	1.6	1.9	0.5	1.1
Medication: Paracetamol	1.4	2.3	4.8	-1.4	-2.2	-0.5	-1.9	1.0	-2.0	-0.4	-0.1	-2.2
Headache pain in last month	2.0	3.4	11.4	-2.2	2.1	-2.5	-0.0	-3.4	-0.3	-0.2	-0.7	-1.9
Medication for cholesterol, blood pressure or diabetes	0.5	0.9	3.9	1.0	-0.9	0.8	-0.1	1.2	0.5	-0.2	2.0	0.1
Glaucoma (self-reported)	0.4	0.4	1.3	0.5	0.5	0.7	0.0	-0.9	0.0	-0.5	-1.1	0.6
Gout (self-reported)	1.0	1.3	3.0	-1.5	-1.3	0.1	-0.0	-0.5	-1.7	-0.9	-1.1	-1.7
Hypothyroidism/myxoedema (self-reported)	3.1	6.1	22.4	0.0	4.7	-0.2	3.1	-2.6	3.1	0.3	0.3	2.5
Medication: Amlodipine	0.6	0.8	2.6	-0.2	0.8	-1.5	-0.3	-0.8	-0.7	-0.7	-1.6	0.3
Medication: Ventolin 100micrograms inhaler	0.4	0.5	1.6	-0.2	-1.1	1.0	-0.1	-0.2	-0.6	0.2	-1.3	-0.3
Birth weight	0.3	0.7	3.5	0.2	-1.1	0.7	0.4	1.9	-0.0	-0.4	0.6	0.7
Chronic bronchitis/emphysema (mother)	0.9	1.1	4.9	-2.2	-0.2	0.8	-0.4	0.4	-1.2	-1.5	-0.6	-0.2
High blood pressure (siblings)	0.6	0.9	2.6	-1.2	0.7	-0.3	-0.2	-0.8	-0.9	-1.3	-1.6	0.0
Forced vital capacity (FVC), Best measure	0.5	1.7	3.5	-1.1	1.8	1.4	1.9	-1.2	1.5	1.2	0.0	0.4
Body fat percentage	0.3	1.2	3.5	-1.2	0.1	-1.3	1.9	-1.4	-0.8	-1.2	-0.4	-0.7
Leg fat percentage (right)	0.3	1.0	2.8	-1.0	-0.2	-1.5	1.7	-1.1	-0.6	-0.8	0.2	-0.7
Arm fat-free mass (right)	0.5	2.4	9.7	-1.5	0.9	-0.2	3.1	-0.8	2.0	1.0	0.6	1.8
Exposure to tobacco smoke outside home	0.6	0.8	2.8	-0.9	-1.7	0.7	0.8	1.5	-0.4	0.1	0.1	0.6
Comparative body size at age 10	0.5	1.4	9.2	-3.0	0.6	-0.2	1.3	0.1	0.2	-0.4	-0.3	0.9
Number of full brothers	0.7	0.9	2.1	0.9	-0.6	-0.8	-1.3	0.5	-1.5	-1.1	-0.7	-0.5
Worry too long after embarrassment	0.3	0.6	2.0	-0.6	1.4	-0.9	0.5	-1.0	0.7	-0.0	0.6	0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.7	0.9	2.0	-1.4	0.8	-1.0	0.3	-0.9	0.6	1.1	0.9	-0.8
Wheeze or whistling in the chest in last year	0.7	1.3	5.6	0.9	1.3	-0.0	2.4	-0.1	0.1	-0.1	-1.2	1.3
Number of children fathered	0.9	1.0	1.9	0.9	1.4	-1.1	0.6	-0.7	1.2	0.7	0.9	1.1
Reason for reducing amount of alcohol drunk: Health precaution	1.0	1.2	2.4	1.5	1.4	-0.4	0.9	-0.2	1.1	0.9	-0.8	1.5
Age at first live birth	0.1	0.2	0.5	0.4	0.1	0.7	0.6	-0.3	0.6	0.4	0.6	-0.2
Pulse wave peak to peak time	0.8	0.9	2.2	-0.3	-0.6	0.5	1.2	0.4	1.5	1.4	0.7	1.0
Health satisfaction	0.8	1.0	5.6	-2.4	0.8	-0.1	1.0	-1.3	-0.0	-0.3	0.1	-0.2
Shortness of breath walking on level ground	1.1	1.3	3.0	-1.7	0.3	-1.6	0.8	-1.4	-0.4	-1.1	0.8	-1.2
Qualifications: College or University degree	0.2	0.5	1.0	0.9	0.6	1.0	-0.5	-0.6	1.0	0.5	0.2	0.6
Eye problems/disorders: None of the above	1.0	1.1	2.7	-0.9	-1.0	-1.0	-1.6	0.4	-1.6	-0.8	-0.7	-0.9
Mouth/teeth dental problems: Loose teeth	1.3	1.6	6.6	1.2	-1.0	-0.5	-0.4	2.6	-0.1	0.8	1.9	0.4
Emphysema/chronic bronchitis	0.9	1.0	2.1	0.2	-0.8	1.3	1.4	0.1	-1.4	-0.8	-1.3	-0.5
Medication for pain relief, constipation, heartburn	1.3	2.2	5.0	1.6	0.9	1.6	1.3	0.1	2.2	1.9	0.5	1.7
Neck or shoulder pain in last month	0.6	0.8	2.0	-0.3	-1.4	1.0	-0.6	0.8	-0.5	0.9	0.9	-1.3
Medication: Blood pressure	0.5	0.8	2.3	-0.6	0.5	-1.5	-1.3	-0.7	-0.4	0.0	-1.4	0.3
Angina (self-reported)	1.0	1.4	4.3	1.7	1.1	-1.2	2.1	-1.4	0.5	-0.1	-0.5	-0.0
Migraine (self-reported)	1.6	1.9	5.2	0.1	1.3	1.7	1.1	-2.0	1.1	0.4	-2.3	1.0
Medication: Ibuprofen	2.0	2.3	6.6	1.1	2.1	-0.1	1.2	0.8	1.9	0.7	1.6	2.6
Medication: Allopurinol	0.4	0.5	1.8	-0.8	0.0	-0.4	0.2	-1.0	-0.7	0.0	-1.3	-0.4
Medication: Omeprazole	0.9	1.1	2.7	-0.0	0.3	-0.7	1.0	-1.6	-1.0	-1.6	-0.3	-1.3
Medication: Seretide 50 evohaler	0.6	0.7	1.7	-0.6	0.2	-1.1	-1.3	-0.1	-0.7	-1.3	-0.9	0.0
Mean time to correctly identify matches	0.4	0.8	2.2	0.5	-0.5	0.6	-0.7	1.5	0.4	1.0	-0.2	1.5
Heart disease (mother)	0.8	0.9	2.6	-0.4	-0.3	1.5	-0.8	1.6	-0.5	-0.1	-0.9	1.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.4	1.7	7.9	0.3	-0.8	-1.3	1.1	1.4	-0.3	0.3	2.8	-1.2
Whole body fat mass	0.3	1.2	4.9	-1.7	0.2	-1.1	2.2	-1.3	0.0	-0.5	-0.2	-0.0
Leg fat mass (right)	0.3	1.1	5.5	-1.3	0.2	-1.2	2.3	-1.2	0.2	-0.4	0.2	0.1
Arm predicted mass (right)	0.5	2.5	10.4	-1.5	1.1	-0.2	3.2	-0.7	1.9	0.9	0.6	1.8
Pulse rate, automated reading	0.1	0.2	0.8	-0.9	0.0	0.6	0.2	0.0	-0.2	-0.8	0.5	-0.1
Alcohol intake frequency.	0.4	1.0	1.9	-0.8	-1.2	-1.1	-1.4	1.4	-0.8	0.6	0.3	-0.7
Comparative height size at age 10	0.2	1.3	2.6	0.2	1.6	-1.5	1.6	-1.5	0.8	-0.4	1.2	-0.4
Number of full sisters	0.4	0.5	1.3	0.2	-0.8	-0.4	-1.1	-0.1	-0.8	-0.8	-0.2	-0.8
Suffer from ‘nerves’	0.4	0.6	1.3	0.5	-0.6	1.1	-1.1	-0.1	0.5	0.1	-1.1	1.0
Overall health rating	0.1	0.1	0.7	-0.8	-0.1	-0.3	0.3	0.0	-0.4	-0.0	-0.2	-0.0
Chest pain or discomfort	1.1	1.6	6.1	0.0	1.2	-2.0	0.8	-2.5	-0.1	0.0	-0.2	-1.5
Had major operations	0.7	0.8	2.4	0.1	-1.4	-1.6	0.0	-0.0	-0.8	0.2	0.5	-1.3
Age at last live birth	0.8	1.2	4.7	2.2	-0.9	1.1	-0.5	0.9	0.3	1.0	1.3	-0.4
Family relationship satisfaction	0.6	0.7	2.6	-0.3	-1.6	0.6	0.1	1.1	0.2	0.8	1.2	-0.0
Leg pain on walking	0.6	0.8	2.8	-1.7	-0.2	-0.4	1.1	-1.0	-0.2	-0.3	0.4	-1.1
Qualifications: NVQ or HND or HNC or equivalent	1.2	1.4	3.5	-1.1	-1.2	-1.9	-0.8	-0.4	-1.1	-1.8	-0.8	-0.6
Commuting to job workplace: Car/motor vehicle	1.7	1.9	7.3	-0.8	-2.7	-1.1	0.8	1.6	-0.8	-0.6	1.6	-1.1
Illness, injury, bereavement, stress in last 2 years	0.7	0.9	2.4	0.6	1.2	1.2	0.8	-0.9	0.0	-0.4	-1.6	0.7
Medication: Aspirin	0.6	0.8	2.3	0.0	0.6	-0.0	0.3	-1.5	-0.3	-1.5	-1.4	-0.0
Supplements: Vitamin C	0.5	0.6	1.9	-0.8	-0.9	-0.3	-1.4	-0.2	-0.7	-0.5	-0.0	-1.0
Knee pain experienced in last month	1.1	1.7	9.2	-0.9	-1.3	0.5	0.2	1.6	0.3	0.4	3.0	-0.5
Hypertension (Self-reported)	0.5	1.5	4.3	-1.3	0.4	-1.0	-1.4	-1.8	-0.7	0.2	-2.1	-0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	3.2	3.8	10.5	-0.8	1.6	-1.2	0.9	-3.2	-1.7	-2.4	-2.4	-2.0
Illnesses of father: Heart disease	0.9	1.2	4.6	-0.8	-1.8	1.3	0.0	2.1	-0.7	0.5	0.0	-0.4
Illnesses of siblings: Diabetes	0.1	0.2	0.7	-0.1	0.5	-0.2	0.8	-0.4	0.3	0.4	-0.2	0.0
Smoking status: Previous	0.5	0.8	3.5	0.9	-0.5	0.6	-0.2	-0.6	1.2	1.9	-0.1	0.5
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.5	1.3	1.0	-0.1	-1.2	0.4	-0.2	0.4	-1.0	0.7	0.6
Whole body fat-free mass	0.4	2.2	6.1	-1.7	0.7	-0.2	2.5	-0.3	2.0	0.9	0.7	2.1
Leg fat-free mass (right)	0.3	1.6	4.5	-2.1	0.3	0.1	1.7	-0.1	1.5	0.9	0.0	2.0
Arm fat percentage (left)	0.2	1.0	4.5	-2.1	-0.8	-0.8	0.7	-0.4	-1.0	-0.9	-0.5	-0.5
Average weekly red wine intake	0.4	0.6	2.4	1.0	-0.1	0.4	-0.4	0.1	-0.9	-0.7	-1.5	0.4
Handedness (chirality/laterality): Left-handed	0.4	0.5	1.4	1.2	-0.2	-0.8	-0.7	0.4	-0.2	1.1	0.1	-0.4
Mood swings	0.4	0.7	2.2	-1.5	1.2	-0.1	0.3	-1.4	0.3	0.1	-0.9	0.4
Loneliness, isolation	0.7	1.0	4.9	-2.2	1.3	-0.3	0.3	-1.2	0.1	0.3	-0.4	-0.3
Long-standing illness, disability or infirmity	1.1	1.6	7.0	-2.6	0.3	-1.3	0.5	-1.3	-0.6	-0.6	0.5	-1.7
Ever had bowel cancer screening	1.1	1.3	3.6	-1.0	1.1	-0.4	1.9	-1.9	0.5	1.0	-0.2	-1.1
Diabetes diagnosed by doctor	0.3	0.5	1.2	1.1	-0.9	-0.0	-0.5	-0.4	-1.0	-0.7	-0.5	-0.9
Ever had stillbirth, spontaneous miscarriage or termination	0.8	0.9	2.3	0.5	1.0	-0.6	0.6	-0.1	1.5	1.4	0.7	1.0
Friendships satisfaction	0.5	0.6	2.6	-1.1	-0.3	-0.5	1.6	-0.4	0.8	0.6	0.3	0.3
Qualifications: nursing, teaching	0.2	0.3	1.6	0.3	-1.3	-0.6	-0.2	-0.0	-0.4	-0.6	0.2	-0.6
Commuting to job workplace: Walk	1.0	1.1	3.0	1.7	-0.5	1.2	-1.7	0.3	0.4	0.1	-0.9	1.2
Eye problems/disorders: Cataract	1.2	1.3	3.6	1.3	-0.1	1.4	1.1	0.5	1.6	1.9	0.6	0.7
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	1.0	0.3	0.0	0.6	1.0	-0.3	0.1	0.6	-1.0	0.3
Medication for cholesterol	1.7	2.6	7.2	1.5	-0.4	1.5	1.1	2.7	1.1	1.7	1.3	2.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.9	1.1	3.8	-0.1	1.9	-0.7	0.4	-1.9	1.0	0.8	-0.1	-0.0
Back pain experienced in last month	0.9	1.2	2.7	-1.4	-1.1	-1.6	-1.6	-0.4	-1.0	-0.7	0.2	-1.1
Mineral and other dietary supplements	0.7	0.9	3.1	-0.4	0.8	-0.6	0.8	-1.4	-0.5	-0.8	0.4	-1.8
Breast cancer (self-reported)	0.8	1.0	4.1	-2.0	-0.1	0.3	-0.9	1.2	0.6	0.6	0.6	1.2
Asthma (self-reported)	0.8	1.7	5.5	-1.3	-0.1	-1.0	-0.3	-0.3	-2.0	-1.2	-1.0	-2.4
Osteoporosis (self-reported)	0.9	1.1	5.9	2.4	0.3	-0.4	0.5	-0.8	0.7	1.4	-0.0	0.2
Osteoarthritis (self-reported)	1.2	1.5	5.3	-1.4	-1.5	-0.9	-0.4	0.3	-0.5	-0.3	2.3	-1.6
Medication: Aspirin	0.7	1.0	3.5	0.1	0.5	-0.4	-0.3	-1.2	-1.0	-1.9	-1.4	-0.4
Medication: Gliclazide	0.5	0.6	1.7	-0.1	-0.4	-1.2	0.1	-0.8	0.0	0.4	0.9	-1.3
Illnesses of father: None of the above (group 1)	0.4	0.4	1.0	-0.6	-0.4	-1.0	-0.6	-0.6	-0.6	-0.7	0.1	-0.9
Smoking status: Current	0.5	0.8	4.6	0.5	-2.2	0.7	-0.7	0.6	-0.4	0.2	-0.2	-1.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.9	1.9	6.0	-2.4	1.2	0.2	-0.6	-2.4	-0.5	-0.7	-1.3	-0.8
Whole body water mass	0.4	2.1	5.6	-1.8	0.7	-0.2	2.4	-0.3	2.0	0.9	0.6	2.1
Leg predicted mass (right)	0.3	1.6	4.5	-2.1	0.3	0.0	1.8	-0.1	1.5	0.9	0.0	2.0
Arm fat mass (left)	0.3	1.0	5.8	-2.4	-0.1	-0.8	1.4	-0.8	0.1	-0.4	-0.1	0.4
Number of self-reported non-cancer illnesses	2.4	4.2	11.6	-2.2	-0.0	-0.6	-1.5	-2.7	-2.5	-1.3	-1.8	-3.4
Average weekly champagne plus white wine intake	0.6	0.8	3.6	-0.6	1.1	-0.3	1.2	-1.9	0.5	-0.7	0.1	-0.5
Miserableness	0.5	0.8	2.4	-0.3	1.4	-0.0	1.5	-1.3	0.9	0.3	-0.3	0.7
Guilty feelings	0.9	1.3	3.4	1.1	-0.2	1.4	1.5	0.7	1.5	0.6	0.5	1.8
Wears glasses or contact lenses	0.8	0.9	4.2	0.6	2.1	-0.9	0.2	-1.5	0.4	0.1	-0.7	0.2
Ever taken oral contraceptive pill	0.4	0.5	2.0	-1.4	0.5	0.1	0.7	0.3	0.4	0.2	0.5	0.9
Hearing aid user	1.7	1.9	4.9	-1.8	-0.9	-1.9	0.2	-1.9	-0.5	-0.2	0.7	-2.2
Mother’s age at death	0.6	0.8	2.5	-0.4	-1.0	-0.9	0.8	0.5	0.2	0.9	1.6	-0.9
Financial situation satisfaction	1.4	1.7	4.0	-0.5	1.2	-0.2	1.6	-0.6	1.8	2.0	1.3	1.2
Tinnitus: Yes, now most or all of the time	0.7	0.8	2.4	-1.1	0.6	-1.5	-0.4	-0.8	-0.5	-0.7	-1.2	0.1
Commuting to job workplace: Public transport	0.4	0.5	1.4	0.8	0.6	-0.5	-1.2	-0.2	-0.7	-1.1	0.2	-0.5
Eye problems/disorders: Glaucoma	0.7	0.9	3.5	0.0	0.8	-0.1	-0.6	-1.9	-0.7	-0.8	-1.2	-0.7
Medication: Blood pressure	1.1	2.1	5.0	-1.6	0.6	-1.6	-0.8	-2.2	-1.2	-1.2	-1.7	-1.6
Pain type(s) experienced in last month: Hip pain	1.1	1.4	3.6	0.2	-1.9	1.1	-0.2	1.6	-0.8	0.3	1.6	-1.2
Supplements: Fish oil (including cod liver oil)	1.0	1.3	3.7	-0.6	-1.6	0.6	-1.6	1.9	-0.5	0.6	-0.7	0.9
High cholesterol (Self-reported)	0.2	0.4	1.1	1.0	-0.3	-0.2	0.6	-0.9	-0.3	-0.5	-1.0	-0.2
Medication: Bendroflumethiazide	0.7	1.1	3.9	-0.3	2.0	-1.9	-0.5	-1.2	0.5	0.1	0.3	0.3
Medication: Paracetamol	1.0	1.6	4.8	-1.7	-1.3	-0.9	-1.2	0.4	-1.6	-0.2	0.1	-2.2
Medication: Lisinopril	3.6	4.7	16.3	-4.0	-1.0	-2.5	0.5	-2.0	-1.8	-1.8	-0.0	-2.9
Medication: Atorvastatin	1.3	1.6	4.1	1.9	1.4	0.3	2.0	-2.0	0.4	-0.1	-0.6	-0.4
Illnesses of father: High blood pressure	0.4	0.5	1.7	0.3	0.3	-0.6	0.1	-0.3	-1.3	-0.9	-0.6	-1.1
Alcohol drinker status: Never	0.6	0.8	2.2	0.5	0.1	-1.5	-1.1	1.4	-0.9	-0.6	0.0	0.4
Ever smoked	0.6	1.1	3.6	1.3	-0.6	0.9	-0.9	-0.5	0.5	1.2	-1.9	0.5
Basal metabolic rate	0.4	1.9	6.0	-2.0	0.6	-0.3	2.4	-0.5	1.7	0.6	0.5	1.8
Leg fat percentage (left)	0.4	1.3	3.2	-1.4	0.1	-1.8	1.7	-1.4	-0.5	-0.9	0.1	-0.7
Arm fat-free mass (left)	0.5	2.7	9.5	-2.0	1.2	-0.6	3.1	-1.1	2.0	0.7	0.6	1.8
Number of operations (self-reported)	0.6	0.9	3.4	-0.1	0.5	0.2	0.1	-1.8	0.0	1.0	-1.8	-0.6
Average weekly beer plus cider intake	2.3	3.3	7.4	-1.8	-1.9	-1.5	-2.7	-0.1	-2.2	-1.3	-2.1	-1.5
Irritability	0.5	0.9	2.5	1.4	-0.3	1.0	-1.0	0.2	0.6	0.0	-1.1	1.6
Risk taking	0.2	0.4	0.7	-0.5	-0.9	-0.8	0.0	0.4	-0.9	-0.5	0.1	-0.7
Ever had prostate specific antigen (PSA) test	0.8	0.9	3.2	1.7	0.1	-0.4	0.6	-0.0	1.1	0.5	1.8	0.0
Fractured/broken bones in last 5 years	1.3	1.7	4.2	1.4	-1.4	0.7	-0.7	1.0	1.2	2.1	2.1	-0.1
Age started oral contraceptive pill	2.7	3.4	9.1	-2.0	-0.7	-1.2	-1.9	-0.1	-3.0	-1.7	-0.2	-3.0
Diastolic blood pressure, automated reading	0.6	1.9	9.1	-3.0	-0.6	-0.2	-0.6	-0.9	-1.5	-0.1	-1.8	-1.2
Ever depressed for a whole week	1.8	2.2	4.8	1.6	2.2	0.1	1.8	-2.0	1.4	0.8	-1.1	1.2
Unable to work because of sickness or disability	0.8	1.1	2.8	-1.7	-0.8	1.6	0.9	-0.8	1.0	1.0	-0.5	0.3
Commuting to job workplace: Cycle	0.6	0.8	2.8	0.7	-0.1	-0.8	-1.7	1.2	0.3	-0.0	1.1	0.4
Myopia	0.8	1.2	4.9	-0.0	1.3	0.4	0.7	-0.8	0.6	0.4	-2.2	1.5
Vascular/heart problems diagnosed by doctor	0.4	1.2	2.5	1.4	-0.1	1.2	0.8	1.6	0.9	-0.0	1.5	1.2
Cholesterol lowering medication	0.5	0.7	3.2	0.7	0.5	-0.6	0.6	-1.8	0.1	-1.1	-0.0	-0.8
Medication: Omeprazole (e.g. Zanprol)	1.4	1.7	5.9	0.1	0.3	-1.1	1.1	-1.6	-1.4	-2.4	-0.3	-1.7
Pain experienced in last month	1.1	1.8	7.9	2.8	-0.1	0.7	0.0	1.3	-0.1	-1.1	-1.2	1.9
Supplements: Calcium	1.1	1.2	4.4	-0.6	-1.3	0.5	-2.1	1.5	-0.2	0.3	-1.0	0.9
Basal cell carcinoma (self-reported)	1.1	1.4	7.9	0.7	0.4	-0.0	-2.8	0.1	-0.4	-0.6	-1.5	0.9
Heart attack/myocardial infarction (self-reported)	1.4	1.8	5.8	2.4	0.8	0.7	1.2	0.9	1.5	1.6	0.7	1.4
Deep venous thrombosis (DVT) (self-reported)	0.7	0.9	3.1	1.0	-0.5	0.1	0.6	0.2	1.4	1.8	0.6	0.9
Heart disease (siblings)	1.1	1.4	4.5	1.4	-0.8	-1.0	-1.3	0.7	-1.4	0.1	-2.1	0.2
Alcohol drinker status: Previous	0.8	1.0	2.6	-1.6	-1.1	-0.2	-1.0	0.2	-1.1	-0.1	-0.4	-1.5
Pack years of smoking	1.4	2.0	6.0	-1.1	0.5	2.4	1.5	1.1	1.6	1.3	1.2	1.4
Impedance of whole body	0.5	2.4	11.0	3.3	1.0	-0.2	0.2	-1.0	-1.4	-1.3	-0.4	-2.2
Leg fat mass (left)	0.3	1.3	5.7	-1.7	0.3	-1.3	2.4	-1.3	0.2	-0.4	0.1	0.0
Arm predicted mass (left)	0.5	2.8	8.9	-1.9	1.1	-0.2	3.0	-0.7	2.2	1.0	0.9	2.0