TWAS hub - DROSHA

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Aorta	0.349	0.0840	2.0e-04	0.063	NA	0.053	NA	0.096	2.2e-04	NA	6.9e-04	NA	6.2e-06
2	GTEx	Artery Tibial	0.204	0.0529	4.3e-04	0.109	NA	0.088	NA	0.089	7.4e-09	NA	2.1e-07	NA	1.7e-07
3	GTEx	Colon Transverse	0.255	0.0830	3.9e-03	0.066	NA	0.035	NA	0.026	4.5e-04	NA	8.9e-03	NA	2.2e-02
4	GTEx	Esophagus Mucosa	0.176	0.0630	6.5e-03	0.045	NA	0.040	NA	0.046	5.5e-04	NA	1.2e-03	NA	4.9e-04
5	GTEx	Esophagus Muscularis	0.239	0.0630	2.1e-04	0.090	NA	0.133	NA	0.112	4.3e-06	NA	1.9e-08	NA	2.8e-07
6	GTEx	Nerve Tibial	0.387	0.0563	6.2e-10	0.224	NA	0.224	NA	0.171	7.6e-16	NA	7.9e-16	NA	3.7e-12
7	GTEx	Pancreas	0.301	0.0880	9.9e-04	0.106	NA	0.061	NA	0.015	3.3e-05	NA	1.5e-03	NA	7.3e-02
8	GTEx	Skin Not Sun Exposed Suprapubic	0.263	0.0790	2.7e-03	0.113	NA	0.094	NA	0.049	9.6e-07	NA	8.1e-06	NA	1.1e-03
9	GTEx	Thyroid	0.266	0.0540	3.2e-06	0.230	NA	0.212	NA	0.224	1.6e-17	NA	3.9e-16	NA	4.5e-17
10	METSIM	Adipose	0.262	0.0361	0.0e+00	0.139	0.157	0.241	0.101	0.079	3.1e-20	8.7e-23	1.3e-35	7e-15	7.4e-12

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Tense / ‘highly strung’	8.6	14.2	23.7	-3.8	-4.3	-3.8	-2.6	-2.8	-4.9	-3.3	-4.2	-4.1	-3.4
Forced expiratory volume in 1-second (FEV1), predicted	6.0	12.6	19.2	-4.0	-4.4	-3.1	-1.9	-3.5	-4.2	-3.4	-4.2	-3.7	-2.2
Chronic bronchitis/emphysema (mother)	4.6	5.4	9.1	2.3	2.7	2.9	0.8	2.3	3.0	1.5	3.0	2.5	1.0
Medication: Atorvastatin	4.1	5.1	9.9	-1.2	-1.6	-2.3	-2.6	-0.9	-2.1	-2.4	-3.1	-2.4	-2.9
Exposure to tobacco smoke at home	3.6	4.0	6.4	1.7	2.0	1.9	1.2	2.2	2.5	1.2	2.3	2.1	2.3
Hair/balding pattern: Pattern 2	3.5	4.4	7.8	0.1	0.8	2.4	2.6	1.6	2.2	2.5	2.8	2.7	1.5
Time employed in main current job	3.5	4.0	6.4	2.0	2.5	1.6	1.1	1.7	2.4	2.4	1.8	2.2	2.0
Handedness (chirality/laterality): Left-handed	3.4	4.1	10.2	2.6	2.7	1.9	0.9	3.2	2.1	1.5	1.9	1.3	0.4
Hearing aid user	3.4	3.8	6.4	1.3	1.5	1.7	1.7	2.5	2.5	2.2	1.9	2.1	1.8
Glaucoma (self-reported)	3.1	3.7	5.8	-1.7	-2.3	-1.4	-2.0	-2.4	-2.4	-0.6	-1.8	-2.0	-2.0
Average weekly beer plus cider intake	3.0	4.4	7.2	1.8	1.6	2.2	2.7	1.5	1.5	2.6	2.4	2.1	2.1
Alcohol intake versus 10 years previously	2.9	4.3	7.3	0.8	1.1	1.9	2.2	2.7	2.3	2.0	2.4	2.0	2.4
Reason for reducing amount of alcohol drunk: Health precaution	2.7	3.2	4.9	-1.0	-1.9	-2.1	-1.5	-1.5	-2.2	-1.0	-2.2	-2.0	-1.8
Heart attack	2.6	3.3	7.2	-1.6	-1.4	-2.7	-1.8	-1.2	-2.1	-1.2	-1.9	-2.3	-1.2
Heart attack/myocardial infarction (self-reported)	2.6	3.3	7.5	-1.5	-1.3	-2.7	-1.6	-1.2	-2.1	-1.3	-2.0	-2.4	-1.4
Prospective memory result	2.4	2.9	7.6	-1.6	-2.8	-1.0	-0.2	-1.3	-1.7	-2.6	-1.4	-1.1	-1.7
Worry (Nagel 2018)	2.3	4.8	6.4	-1.9	-2.1	-2.1	-2.2	-1.9	-2.4	-1.8	-2.3	-2.5	-2.5
Noisy workplace	2.3	2.8	4.3	1.9	1.9	0.8	1.6	2.1	1.9	1.3	1.6	1.3	1.9
Major Depression (MDD)	2.2	2.7	4.6	-0.2	-0.7	-1.7	-2.0	-1.3	-1.9	-2.2	-1.9	-2.0	-1.6
Height	2.2	42.8	83.6	-9.0	-9.1	-5.4	-5.0	-7.0	-6.1	-4.1	-6.7	-5.3	-5.8
Illnesses of mother	2.2	2.8	4.7	1.8	1.6	2.0	1.2	2.2	1.8	0.5	1.8	1.8	1.4
Hand grip strength (left)	2.1	5.6	11.8	1.3	1.3	2.1	3.4	0.8	2.0	3.4	2.8	2.9	2.0
Commuting to job workplace: Public transport	2.1	2.5	6.3	0.9	0.8	1.7	1.9	1.5	1.2	2.5	1.5	1.7	1.1
Neuroticism	2.0	4.8	6.0	-1.7	-1.9	-2.1	-2.0	-2.2	-2.3	-2.4	-2.4	-2.4	-2.4
Mouth/teeth dental problems: Dentures	2.0	3.4	8.1	2.5	2.8	1.5	1.0	1.8	2.3	1.6	1.6	1.6	0.8
Mean Putamen Volume	1.9	2.2	3.7	1.0	1.0	1.9	1.2	1.5	1.5	1.6	1.4	1.4	1.9
Supplements: Glucosamine	1.9	2.5	7.0	-0.2	-0.7	-1.1	-2.6	-0.7	-1.5	-1.9	-2.0	-1.8	-1.4
Mouth/teeth dental problems: Loose teeth	1.9	2.3	6.7	0.4	0.5	1.1	2.1	2.6	1.5	1.1	1.0	1.3	1.9
Comparative height size at age 10	1.9	10.4	17.6	-4.2	-4.0	-2.6	-3.1	-3.4	-3.0	-1.9	-3.2	-2.7	-3.6
Ever had bowel cancer screening	1.9	2.3	6.3	-1.1	-0.6	-1.2	-2.5	-0.9	-1.1	-1.3	-1.7	-1.4	-2.2
Ulcerative Colitis	1.8	2.6	7.7	-1.0	-0.0	-2.0	-1.4	0.4	-1.6	-1.8	-2.1	-2.8	-1.1
Standing height	1.8	18.2	33.5	-5.7	-5.8	-3.7	-2.9	-4.8	-4.3	-2.8	-4.3	-3.6	-3.5
Chronic bronchitis/emphysema (father)	1.7	2.0	6.4	-0.7	-0.9	-0.6	-2.2	-2.0	-1.0	0.6	-0.9	-1.1	-2.5
Neuroticism score	1.7	3.6	4.7	-1.8	-2.2	-1.3	-1.5	-2.0	-2.2	-1.9	-1.9	-1.9	-2.0
Depression (self-reported)	1.7	2.1	4.3	-0.3	-1.1	-1.6	-1.4	-1.2	-2.1	-0.3	-2.1	-1.9	-1.0
Pulse wave Arterial Stiffness index	1.7	2.0	5.3	-1.3	-0.8	-0.6	-2.3	-1.5	-1.6	-1.1	-1.2	-0.6	-2.1
Ulcerative Colitis (UC)	1.6	3.0	7.8	-1.5	-0.3	-2.1	-1.5	0.7	-1.8	-2.1	-1.7	-2.8	-1.4
Diabetes (father)	1.6	1.9	4.9	-0.0	0.7	0.8	2.2	1.7	1.6	1.7	0.9	1.0	1.7
Ever unenthusiastic/disinterested for a whole week	1.6	2.0	2.9	1.3	1.4	1.5	1.6	1.7	0.8	0.9	1.6	1.6	1.4
Shortness of breath walking on level ground	1.6	2.0	3.7	-0.7	-0.7	-1.4	-1.9	-1.3	-1.7	0.1	-1.9	-1.2	-1.8
Chest pain or discomfort	1.6	2.3	4.0	-1.4	-1.9	-1.1	-1.9	-1.4	-2.0	-1.1	-1.5	-1.3	-1.3
Smoking status: Previous	1.6	2.4	5.2	-1.7	-1.6	-1.4	-1.8	-2.3	-2.0	-0.1	-1.0	-1.0	-1.4
Neuroticism (Nagel 2018)	1.5	3.6	6.7	-1.2	-1.3	-1.9	-2.4	-1.3	-1.7	-1.3	-2.4	-2.6	-2.1
Number of treatments/medications taken	1.5	2.6	4.4	-1.7	-1.6	-2.1	-1.4	0.2	-1.6	-1.2	-1.9	-1.8	-1.9
Impedance of leg (left)	1.5	7.3	9.8	-2.7	-2.3	-2.9	-2.3	-2.8	-2.7	-2.8	-2.6	-3.1	-2.5
Fractured/broken bones in last 5 years	1.5	1.9	3.8	1.3	1.7	0.7	0.7	1.9	1.9	1.4	1.8	1.1	0.3
Alcohol drinker status: Previous	1.5	1.7	2.7	-0.9	-1.2	-1.3	-1.4	0.0	-1.6	-1.6	-1.2	-1.3	-1.5
Heel bone mineral density (BMD) T-score, automated (left)	1.4	3.1	4.6	1.3	1.5	1.8	1.7	2.1	2.2	1.1	2.1	2.0	1.6
Ever highly irritable/argumentative for 2 days	1.4	1.7	4.8	0.5	0.8	0.9	1.1	2.2	1.2	0.4	1.2	1.2	2.1
Blood clot in the leg (DVT)	1.4	1.8	8.5	-0.8	-1.1	-0.7	-2.9	-1.7	-0.4	-1.3	-0.9	-0.6	-1.1
Headache pain in last month	1.4	2.3	5.4	1.0	1.8	1.0	1.5	2.3	1.4	1.0	1.5	0.7	2.0
Commuting to job workplace: Car/motor vehicle	1.4	1.6	4.5	-0.3	-0.5	-1.7	-2.1	-2.0	-0.9	-0.7	-1.1	-1.1	-0.8
Medication: Lisinopril	1.4	1.8	3.8	-1.2	-0.8	-1.4	-1.3	-1.6	-0.8	-2.0	-1.6	-1.8	-0.3
Bipolar Disorder (2011)	1.3	1.2	2.9	-1.7	-1.4	-0.7	-0.5	-1.3	-1.4	-0.9	-1.1	-1.0	-0.2
Type 2 Diabetes (T2D) (2018)	1.3	2.5	4.2	0.8	1.4	1.5	2.1	1.5	1.4	1.6	1.8	1.8	1.7
Sensitivity / hurt feelings	1.3	2.2	6.8	-0.5	-0.5	-1.6	-2.6	-0.5	-1.0	-1.8	-1.7	-1.6	-1.4
Ever had hysterectomy (womb removed)	1.3	1.5	2.7	1.0	1.2	1.5	1.2	1.6	1.2	1.1	1.1	1.4	0.5
Vitamin and mineral supplements	1.3	1.7	4.1	1.5	1.1	0.8	1.4	-1.3	0.8	1.5	1.1	1.0	2.0
Hand grip strength (right)	1.3	3.6	8.6	0.5	0.6	1.6	2.9	0.1	1.9	2.9	2.0	2.3	1.6
Father’s age at death	1.3	1.7	5.6	0.4	0.1	-1.2	-2.2	0.2	-0.5	-0.7	-1.3	-1.7	-2.4
Pulse wave peak to peak time	1.3	1.5	4.7	0.9	0.5	0.4	2.2	1.2	1.4	0.9	1.0	0.4	1.9
Heart disease (mother)	1.3	1.5	2.9	0.4	-0.3	-1.1	-1.6	-1.6	-1.7	-0.6	-1.2	-1.5	-1.2
Medication: Gliclazide	1.3	1.5	5.0	2.2	1.8	-0.4	-0.1	2.2	0.9	-0.2	0.1	-0.4	0.5
Illnesses of father: None of the above (group 1)	1.3	1.7	3.1	-0.9	-1.4	-1.0	-1.8	-1.0	-1.4	-1.6	-1.5	-0.9	-1.1
Medication: Levothyroxine sodium	1.2	2.0	5.5	2.2	2.3	1.6	-1.1	1.7	0.7	0.9	1.0	0.8	0.4
Falls in the last year	1.2	1.6	3.3	-0.4	-1.2	-1.4	-0.9	-1.1	-1.4	-1.2	-1.1	-1.6	-1.8
Medication: Ibuprofen (e.g. Nurofen)	1.2	1.5	3.1	-0.8	-0.1	1.8	1.2	1.3	1.4	0.5	0.9	1.8	1.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.2	1.4	4.5	0.3	1.0	0.9	1.6	1.1	1.0	2.1	0.8	1.2	1.0
Commuting to job workplace: Walk	1.2	1.3	3.0	1.2	0.6	1.1	1.6	1.2	1.1	1.7	0.7	0.7	0.8
Mouth/teeth dental problems: Mouth ulcers	1.2	1.9	4.3	1.2	1.7	1.3	0.7	0.9	1.4	2.1	1.9	1.4	0.6
Guilty feelings	1.2	1.8	5.4	-1.2	-1.0	-0.6	-1.6	-2.3	-1.5	-0.6	-1.4	-1.3	-0.8
Financial situation satisfaction	1.2	1.5	3.4	1.8	1.6	1.1	1.5	1.4	1.0	-0.0	1.2	0.7	0.8
Number of operations (self-reported)	1.2	1.8	4.0	-0.0	0.6	1.6	1.1	2.0	1.5	1.9	1.1	1.6	1.0
Irritability	1.2	2.0	5.1	-2.3	-2.1	-1.4	-0.8	-1.2	-1.4	-1.6	-0.9	-1.1	-0.6
Qualifications: None of the above	1.1	2.3	9.7	1.4	1.1	-1.6	-3.1	-0.2	-0.1	-1.1	-1.2	-1.6	-1.7
Supplements: Vitamin C	1.1	1.4	2.4	-0.9	-0.2	-1.5	-1.4	1.2	-0.3	-1.3	-0.7	-1.5	-1.5
Impedance of whole body	1.1	5.6	9.9	-1.8	-1.3	-2.7	-2.6	-2.4	-2.1	-2.4	-2.5	-3.1	-2.2
Depression (Nagel 2018)	1.0	1.5	3.7	0.8	0.1	-1.0	-1.9	-0.5	-1.0	-1.6	-1.4	-1.9	-0.7
Impedance of leg (right)	1.0	4.9	6.7	-2.4	-1.7	-2.4	-1.9	-2.3	-2.2	-2.4	-2.1	-2.6	-2.1
Medication: Cholesterol lowering	1.0	1.6	3.5	-0.3	-0.6	-1.5	-1.9	-0.9	-0.9	-0.2	-1.6	-1.6	-1.9
Peak expiratory flow (PEF)	1.0	2.2	5.1	2.2	1.6	0.7	2.2	2.1	1.2	1.0	1.1	0.9	0.8
Comparative body size at age 10	1.0	2.8	8.3	1.3	1.6	-1.8	-2.9	0.1	-1.3	-0.5	-1.2	-2.4	-1.7
Neck or shoulder pain in last month	1.0	1.4	5.2	-0.2	0.6	-1.3	-2.3	0.6	-0.5	-1.3	-1.3	-1.4	-1.0
Medication: Aspirin	1.0	1.3	3.2	-0.4	-0.3	-1.5	-1.8	0.3	-1.0	-1.0	-1.0	-1.8	-1.3
Age started oral contraceptive pill	1.0	1.2	4.4	2.1	1.4	0.9	-1.1	0.5	0.9	1.3	0.4	0.7	0.2
Deep venous thrombosis (DVT) (self-reported)	1.0	1.3	7.1	-0.5	-0.8	-0.6	-2.7	-1.4	-0.2	-1.1	-0.6	-0.4	-0.9
Irritable Bowel Disease (IBD)	0.9	2.1	5.3	-2.3	-0.8	-1.0	-1.2	0.5	-1.4	-2.0	-1.2	-1.6	-1.3
Ovarian Cancer	0.9	1.2	5.1	-0.9	-0.5	-0.3	-2.2	-0.4	-1.0	-1.7	-1.0	-0.3	-0.7
Average weekly spirits intake	0.9	1.1	4.3	0.2	0.6	2.1	-0.1	0.8	1.1	0.1	1.3	1.7	-0.2
Trunk fat percentage	0.9	3.6	7.0	-0.0	-0.3	-2.3	-2.6	-1.2	-2.1	-1.3	-2.3	-2.5	-2.2
High blood pressure (mother)	0.9	1.3	2.4	-0.9	-1.6	-1.2	-1.0	-1.0	-0.9	-0.1	-1.5	-1.2	-1.5
Trunk fat mass	0.9	3.7	5.5	-0.6	-1.1	-2.2	-2.4	-1.5	-2.3	-1.4	-2.3	-2.3	-2.2
Past tobacco smoking	0.9	1.6	4.0	1.3	1.6	0.9	1.4	1.8	2.0	-0.6	0.9	0.4	0.9
Mouth/teeth dental problems	0.9	1.4	2.8	-1.4	-1.7	-1.1	-1.2	-1.1	-1.4	-1.0	-1.0	-1.0	-0.9
Fluid intelligence score	0.9	2.0	3.5	1.1	0.8	1.6	1.7	1.0	1.4	1.6	1.9	1.5	0.9
Illnesses of siblings	0.9	1.3	4.2	-1.6	-2.0	-0.3	0.6	-1.3	-1.0	-1.3	-0.1	-0.2	1.1
Qualifications: NVQ or HND or HNC or equivalent	0.9	1.1	4.9	-0.1	0.0	0.8	1.9	0.8	0.3	0.7	0.5	0.7	2.2
Smoking status: Current	0.9	1.4	4.6	0.1	-0.5	1.3	2.1	1.2	0.4	1.5	0.5	1.2	1.2
Average weekly champagne plus white wine intake	0.9	1.2	3.0	0.0	0.2	-1.3	-1.7	-1.2	-1.0	-1.4	-0.9	-1.1	-0.7
Other serious medical condition/disability diagnosed by doctor	0.8	1.0	2.3	0.6	0.2	1.0	1.3	0.5	0.7	1.3	1.5	1.4	0.7
Pack years adult smoking proportion	0.8	1.2	1.9	-1.3	-1.4	-1.0	-1.0	-0.7	-0.8	-1.3	-1.3	-1.0	-1.1
Average weekly fortified wine intake	0.8	0.9	2.0	0.5	0.7	1.4	0.3	0.8	1.4	0.7	0.9	1.3	0.8
Hayfever, allergic rhinitis or eczema	0.8	1.7	4.5	0.9	1.1	0.8	2.1	2.0	0.8	0.1	0.7	0.8	2.0
Stomach or abdominal pain in last month	0.8	1.0	2.1	-1.0	-1.0	-1.2	-1.4	-0.6	-0.9	-0.6	-1.1	-1.5	-0.4
Impedance of arm (left)	0.8	3.7	7.8	-1.0	-0.5	-2.3	-2.5	-1.7	-1.4	-2.0	-2.2	-2.8	-1.7
Qualifications: O levels/GCSEs or equivalent	0.8	1.3	3.7	-1.5	-1.8	-0.3	0.8	-1.9	-1.1	-1.1	-0.2	-0.2	-0.6
High blood pressure (siblings)	0.8	1.1	2.9	0.9	1.7	1.0	0.4	0.5	1.0	1.7	0.7	1.4	-0.3
Medication for cholesterol	0.8	1.2	2.9	-0.3	-0.1	1.4	1.4	-0.5	0.7	0.9	1.7	1.7	1.1
Breast cancer (self-reported)	0.8	0.9	2.1	0.4	0.5	0.7	0.8	-0.7	1.5	1.1	1.3	1.2	0.8
Myopia	0.8	1.1	2.4	-1.1	-1.1	-0.9	-1.1	-0.8	-1.4	-0.2	-0.8	-1.1	-1.5
Intelligence (Savage-Jansen 2018)	0.7	2.1	6.1	1.0	0.8	1.8	2.5	1.2	1.1	1.6	1.4	1.5	0.6
Ever used hormone-replacement therapy (HRT)	0.7	0.9	2.0	0.7	1.2	1.3	-0.9	-0.1	0.9	1.4	0.9	0.9	0.6
Fed-up feelings	0.7	1.2	3.0	-1.1	-0.9	-0.5	-0.9	-0.8	-1.4	-0.7	-1.1	-1.1	-1.7
Relative age voice broke	0.7	1.1	4.2	1.7	1.2	0.1	0.7	2.0	0.9	0.3	-0.5	-0.5	0.5
Frequency of tenseness / restlessness in last 2 weeks	0.7	1.1	2.8	1.0	0.6	-1.0	-0.8	-0.8	-1.6	-0.7	-1.0	-1.7	-0.8
Heel bone mineral density (BMD) T-score, automated (right)	0.7	1.6	2.7	1.2	1.2	1.2	0.9	1.3	1.7	0.5	1.5	1.3	1.3
Pain all over the body in last month	0.7	0.7	1.8	-0.3	-1.2	-0.9	0.1	-0.3	-0.5	-1.3	-0.4	-1.0	-1.2
Impedance of arm (right)	0.7	3.4	7.2	-1.0	-0.2	-2.2	-2.7	-1.2	-1.4	-1.7	-2.1	-2.6	-1.8
Medication: Lansoprazole	0.7	0.8	1.8	-1.4	-0.9	-0.7	-1.0	-0.0	-0.9	-1.1	-0.7	-0.9	-0.7
Seen a psychiatrist for nerves, anxiety, tension or depression	0.7	0.9	2.3	-0.6	-0.2	-0.7	-1.3	-0.2	-1.1	-0.5	-1.1	-1.5	-1.0
Mean time to correctly identify matches	0.7	1.4	3.2	-0.0	-0.7	-1.4	-0.9	-1.8	-0.2	-1.4	-1.2	-1.5	-1.4
Illness, injury, bereavement, stress in last 2 years	0.7	0.9	1.9	0.8	1.4	1.2	0.6	0.7	0.5	0.0	1.0	1.1	1.4
Qualifications: nursing, teaching	0.7	1.1	2.2	1.0	1.5	0.4	0.7	1.3	1.3	1.3	1.0	0.4	1.0
Medication: Aspirin	0.7	1.0	2.2	0.0	0.0	-1.3	-1.2	0.7	-0.9	-0.8	-0.7	-1.5	-1.3
Alcohol drinker status: Never	0.7	0.9	2.7	0.0	-0.9	-0.6	-0.6	0.6	-0.7	-1.6	-1.0	-0.6	-1.5
Reaction Time	0.6	1.1	3.7	-0.3	-0.7	-1.2	0.2	-1.4	-0.2	-1.9	-0.8	-1.3	-0.7
Body Mass Index (BMI) (2010)	0.6	0.8	2.5	0.1	0.3	1.3	0.5	-0.2	0.6	1.4	0.9	1.6	0.9
HbA1C	0.6	0.7	4.1	0.6	0.6	0.8	0.9	2.0	0.7	-0.1	0.0	0.1	0.3
Type 2 Diabetes (T2D) (2012)	0.6	0.7	1.5	1.0	0.7	0.9	0.4	1.2	0.5	0.8	0.8	1.0	0.8
Lung FEV1/FVC ratio	0.6	3.2	6.5	2.5	2.2	1.6	1.8	2.3	1.8	1.0	1.4	1.1	1.5
Chronotype (morning person)	0.6	1.4	4.2	0.9	0.8	0.6	1.3	2.1	1.5	0.3	1.4	0.9	1.1
Current tobacco smoking	0.6	1.0	3.9	-0.0	-0.6	1.0	2.0	1.0	0.4	1.4	0.2	1.0	1.0
Medication: Atenolol	0.6	0.7	3.7	0.4	0.5	0.2	0.8	1.1	0.7	1.9	0.6	0.5	0.6
Sitting height	0.6	4.1	9.9	-3.1	-3.0	-1.6	-0.8	-2.5	-1.9	-0.7	-2.0	-1.4	-1.6
Medication for cholesterol, blood pressure or diabetes	0.6	1.0	2.2	-0.1	0.3	1.3	1.4	0.5	0.8	0.1	1.0	1.4	1.5
Hypothyroidism/myxoedema (self-reported)	0.6	1.2	4.1	2.0	1.8	0.7	-1.4	1.2	-0.0	0.2	0.3	0.3	0.4
Forced vital capacity (FVC), Best measure	0.6	2.3	3.5	-1.5	-1.9	-1.5	-0.3	-1.5	-1.6	-1.6	-1.8	-1.5	-1.4
Body fat percentage	0.6	2.4	5.4	0.5	0.0	-1.8	-2.3	-0.8	-1.7	-1.2	-1.7	-1.9	-2.0
Medication: Ibuprofen	0.6	0.8	1.7	-1.0	-0.6	1.1	0.7	0.6	1.3	-0.2	0.5	1.3	0.8
Medication: Allopurinol	0.6	0.8	1.8	0.8	-0.3	-1.4	-1.0	-0.3	-0.9	-0.9	-0.9	-1.3	-0.4
Medication: Omeprazole	0.6	0.7	2.1	-0.5	-0.7	-0.4	-0.8	-0.4	-1.3	-0.9	-0.4	-0.4	-1.4
Whole body fat mass	0.6	2.4	4.1	-0.2	-0.8	-1.7	-2.0	-1.2	-1.9	-1.1	-1.8	-1.7	-2.0
Hypertension (Self-reported)	0.6	1.6	4.0	1.8	1.5	0.9	0.6	2.0	1.0	1.8	1.1	0.3	0.0
Mood swings	0.6	1.0	2.7	-0.7	-0.6	-1.1	-1.2	-0.6	-0.9	0.0	-1.5	-1.6	-1.0
Eye problems/disorders: Cataract	0.6	0.6	1.5	0.8	0.9	0.3	0.4	1.2	0.8	1.2	0.9	0.2	0.5
Osteoporosis (self-reported)	0.6	0.8	1.9	1.4	1.2	1.1	-0.1	0.6	0.5	-0.0	0.7	0.5	1.3
Eye problems/disorders: Glaucoma	0.6	0.7	1.5	-0.8	-0.7	0.4	-1.0	-1.2	-0.6	1.2	-0.1	0.0	-0.9
Ever depressed for a whole week	0.6	0.8	2.9	0.3	0.0	1.4	0.7	0.1	0.5	1.1	0.8	1.7	0.5
Alzheimer’s Disease (in father)	0.5	0.5	1.5	-0.5	-0.6	0.7	1.2	0.9	0.6	0.3	0.6	0.9	0.5
Coronary Artery Disease (CAD)	0.5	0.6	1.6	1.3	0.9	0.6	0.6	0.8	1.1	0.1	0.8	0.6	0.7
Frequency of depressed mood in last 2 weeks	0.5	0.8	2.5	-0.1	-0.6	-0.5	-0.5	-0.6	-1.6	-1.1	-1.0	-1.2	0.1
Hearing difficulty/problems: Yes	0.5	0.8	1.4	0.4	0.8	1.2	0.8	1.0	1.1	0.9	0.8	1.1	0.3
Townsend deprivation index at recruitment	0.5	0.7	2.4	0.0	0.0	1.2	1.0	0.3	0.4	0.3	0.8	1.1	1.5
Nervous feelings	0.5	0.9	2.1	-0.6	-0.6	-0.3	-1.5	-0.6	-0.8	-1.3	-0.8	-0.9	-1.1
Allergy	0.5	1.2	4.0	-0.9	-0.8	-0.9	-1.2	-1.7	-0.7	-0.5	-0.7	-0.9	-2.0
Loud music exposure frequency	0.5	0.5	2.2	0.4	0.3	0.7	1.5	0.4	0.4	-0.2	0.6	1.1	-0.2
Medication: Paracetamol	0.5	0.8	2.6	-0.1	0.5	-1.6	-0.6	0.4	-0.5	-0.1	-0.8	-1.6	-1.1
Number of children fathered	0.5	0.6	2.6	1.1	0.8	0.6	-0.3	1.6	0.5	0.2	0.6	0.5	0.2
Medication: Blood pressure	0.5	1.0	3.3	-0.4	-0.7	-1.8	-0.7	-0.3	-1.0	-0.2	-1.0	-1.6	-0.8
Overall health rating	0.5	1.0	2.3	-0.0	-1.0	-1.0	-1.4	-0.3	-0.8	-0.4	-1.4	-1.5	-1.3
Leg pain on walking	0.5	0.6	2.0	0.8	0.1	0.4	-0.3	1.4	0.6	1.4	0.5	0.8	-0.2
Long-standing illness, disability or infirmity	0.5	0.8	3.0	0.3	0.1	-1.2	-1.7	-0.2	-0.4	0.2	-0.7	-1.0	-1.3
Mineral and other dietary supplements	0.5	0.7	3.4	-0.1	0.1	0.3	1.8	-0.4	0.5	1.4	0.7	0.6	0.9
Osteoarthritis (self-reported)	0.5	0.7	3.2	-0.1	-0.6	-0.2	-1.3	-0.3	-0.1	-1.0	-0.4	-0.2	-1.8
Wears glasses or contact lenses	0.5	0.6	1.8	-0.1	-0.1	1.1	-1.4	-1.1	-0.1	1.1	0.2	0.3	0.4
Ever taken oral contraceptive pill	0.5	0.6	1.5	1.0	1.2	-0.1	1.2	0.7	0.2	-0.5	0.4	-0.1	0.9
Tinnitus: Yes, now most or all of the time	0.5	0.5	1.3	-0.9	-0.7	-1.1	-0.1	-0.2	-0.3	-0.9	-1.0	-0.8	-0.5
Illnesses of father: High blood pressure	0.5	0.7	1.6	1.1	0.8	0.5	1.2	0.2	0.4	0.2	1.3	0.3	1.1
Cholesterol lowering medication	0.5	0.7	2.6	0.2	-0.2	-0.3	-0.9	-0.2	-0.9	-1.2	-1.6	-0.6	-1.1
Pack years of smoking	0.5	0.7	1.3	-1.1	-1.1	-0.7	-1.0	-0.5	-0.4	-1.1	-0.8	-0.6	-0.8
Bipolar Disorder (2018)	0.4	0.6	2.0	0.7	0.6	-0.7	-1.4	-0.2	0.3	0.7	-0.5	-1.4	-0.0
Schizophrenia (2018)	0.4	0.8	3.2	1.8	1.2	0.4	-0.0	1.0	0.0	0.8	0.6	0.4	0.9
Alzheimer’s Disease (in mother)	0.4	0.5	1.6	-1.3	-0.7	-0.2	0.4	-1.2	0.2	-0.9	-0.7	0.0	-0.1
Alzheimer’s Disease (including proxy)	0.4	0.6	1.1	-1.0	-0.9	0.6	1.0	-1.0	0.7	-0.1	0.2	0.9	0.4
Verbal and Numeric Reasoning (VNR)	0.4	1.0	3.2	0.3	-0.1	1.5	1.8	0.3	0.5	1.1	1.0	1.2	-0.1
Smoking Status	0.4	1.0	3.8	-1.4	-1.9	-0.2	0.7	-0.6	-1.3	0.9	-0.6	0.0	-0.3
Hypothyroidism (self reported)	0.4	1.0	3.4	1.9	1.6	0.8	-1.6	0.3	0.2	-0.5	0.6	0.6	0.3
Medication: Co-codamol	0.4	0.4	1.0	0.1	0.2	0.7	1.0	1.0	0.8	0.8	0.5	0.6	-0.3
Maternal smoking around birth	0.4	0.5	1.7	0.0	-0.6	1.3	0.8	-0.2	0.3	-0.0	1.0	1.1	-0.1
High blood pressure	0.4	1.1	3.1	1.6	1.2	0.6	0.3	1.8	0.6	1.6	0.8	0.1	-0.2
Weight	0.4	2.0	3.4	-1.2	-1.7	-1.4	-1.1	-1.1	-1.8	-0.8	-1.9	-1.3	-1.6
Trunk fat-free mass	0.4	2.1	8.7	-2.6	-3.0	-0.4	0.1	-1.4	-1.3	-0.3	-1.0	-0.1	-0.7
Lung cancer (father)	0.4	0.5	1.2	-0.6	-0.3	1.1	-0.4	-0.4	1.0	0.8	0.7	0.9	-0.1
Trunk predicted mass	0.4	2.0	8.6	-2.6	-2.9	-0.4	0.1	-1.4	-1.2	-0.3	-1.0	0.0	-0.7
Breastfed as a baby	0.4	0.5	2.5	1.6	1.2	0.3	-0.4	0.6	0.8	0.1	-0.0	-0.2	-0.3
Gout (self-reported)	0.4	0.6	1.5	1.0	-0.1	-1.1	-0.3	-1.2	-0.8	-0.5	-0.4	-1.0	-0.1
Medication for pain relief, constipation, heartburn	0.4	0.7	4.9	0.7	-0.2	0.6	0.4	-2.2	0.2	0.6	0.2	0.5	0.7
Angina (self-reported)	0.4	0.5	1.1	-0.8	-0.5	-0.8	-1.0	-0.3	-0.6	-0.4	-0.6	-0.5	-1.1
Suffer from ‘nerves’	0.4	0.7	1.6	-0.6	-0.8	-0.9	-0.8	-0.5	-1.1	0.2	-0.8	-1.3	-0.8
Illnesses of siblings: Diabetes	0.4	0.5	1.1	-1.1	-0.3	0.2	-0.2	0.2	-0.7	-1.0	-0.9	-0.1	-1.0
Average weekly red wine intake	0.4	0.6	1.8	-1.3	-0.8	-0.8	-0.3	0.0	-0.7	-0.4	-0.5	-0.9	-1.0
Loneliness, isolation	0.4	0.5	1.8	-1.0	-0.5	1.3	0.6	0.5	0.3	0.9	0.1	0.6	0.6
Back pain experienced in last month	0.4	0.6	1.2	-1.0	-0.3	-0.6	0.6	0.6	-0.6	-1.1	-1.1	-0.9	-0.4
Number of self-reported non-cancer illnesses	0.4	0.7	1.8	-0.6	-1.2	-0.8	-0.3	0.6	-1.3	-0.4	-0.7	-0.9	-0.8
Risk taking	0.4	0.5	2.2	0.5	0.4	-0.2	0.2	1.5	0.3	1.5	0.5	0.2	-0.2
Commuting to job workplace: Cycle	0.4	0.4	1.2	0.2	-0.1	1.1	0.4	0.8	0.9	0.4	0.9	0.3	0.6
Supplements: Calcium	0.4	0.4	1.2	1.1	0.9	0.0	-0.7	0.9	0.7	0.6	0.3	0.3	0.1
Heart disease (siblings)	0.4	0.5	1.6	1.3	1.0	-0.4	0.4	1.0	-0.1	0.3	-0.3	-0.6	0.2
Leg fat mass (left)	0.4	1.5	3.0	0.2	-0.6	-1.3	-1.4	-0.5	-1.7	-0.9	-1.4	-1.4	-1.7
Bipolar Disorder or Schizophrenia	0.3	0.8	3.3	1.8	1.2	-0.1	-0.9	0.7	0.2	1.0	0.2	-0.5	0.9
Depressed Affect (Nagel 2018)	0.3	0.7	1.8	-0.3	-0.0	-0.5	-1.2	0.2	-0.3	-0.2	-1.2	-1.3	-1.3
Schizophrenia vs Biploar Disorder	0.3	0.4	1.6	0.3	0.2	0.4	1.3	0.2	-0.2	0.4	0.5	1.0	0.4
Breast Cancer	0.3	0.7	4.9	-0.7	-0.8	0.4	0.5	0.1	-0.3	-2.2	-0.4	0.2	0.2
Crohns Disease (2012)	0.3	0.4	1.5	-0.1	0.5	0.8	0.1	1.2	0.4	-0.5	0.7	0.7	0.5
HDL Cholesterol	0.3	0.4	1.6	0.7	0.6	0.0	-1.3	-0.6	0.3	-0.3	-0.2	-0.3	-1.1
Neuroticism (2016)	0.3	0.5	1.1	-0.0	0.2	-0.9	0.1	-0.8	-0.7	-0.5	-0.9	-1.1	0.3
Rheumatoid Arthritis	0.3	0.4	1.1	-1.1	-0.7	-0.8	-0.4	0.4	-0.6	-0.6	-0.2	-0.9	0.1
Lung FVC	0.3	1.3	3.2	1.8	1.7	1.3	0.8	0.8	1.0	0.7	1.1	1.2	0.8
Relative age of first facial hair	0.3	0.6	1.4	0.5	-0.3	-0.8	-0.3	1.0	-0.8	-0.0	-1.2	-1.0	-0.7
Taking other prescription medications	0.3	0.4	1.0	-0.6	-0.9	-0.5	-0.4	0.1	-0.8	-0.4	-0.6	-0.4	-1.0
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	1.0	-0.4	0.0	0.5	0.4	0.7	0.4	1.0	0.3	0.8	0.4
Serious illness, injury or assault to yourself	0.3	0.4	1.5	-0.5	-0.9	-1.2	-0.5	0.6	-0.1	-0.4	-0.4	-0.6	-0.3
Multivitamins +/- minerals	0.3	0.3	1.0	-0.3	-0.2	0.1	-0.7	1.0	-0.6	-0.6	-0.3	-0.2	-1.0
Alcohol usually taken with meals	0.3	0.5	1.8	-0.9	-1.0	-1.3	0.0	-0.1	-0.6	0.7	-0.4	-0.6	-0.3
Had other major operations	0.3	0.4	0.8	0.0	0.6	0.9	0.8	0.4	0.2	0.9	0.5	0.8	0.2
Hayfever/allergic rhinitis (self-reported)	0.3	0.3	1.2	-0.4	-0.2	-0.2	0.8	1.1	0.0	-0.4	-0.7	0.0	0.7
Medication: Ramipril	0.3	0.4	1.2	1.0	0.6	-0.0	-0.5	0.8	0.4	1.1	-0.1	-0.3	-0.4
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.6	1.3	-0.3	0.2	-1.1	-0.8	-0.9	-0.7	0.5	-0.6	-1.0	-0.7
Hair/balding pattern: Pattern 3	0.3	0.4	1.5	0.3	0.3	-0.5	0.2	1.2	-0.2	-0.9	-0.5	-0.5	0.9
Birth weight of first child	0.3	0.6	1.6	-0.9	-0.4	-0.9	-0.0	-0.6	-0.4	1.3	-0.9	-1.1	0.3
Medication: Amlodipine	0.3	0.4	1.0	-0.8	-0.8	-0.2	-0.8	0.4	-0.8	-0.4	-1.0	-0.7	-0.2
Medication: Ventolin 100micrograms inhaler	0.3	0.3	1.3	0.1	-0.5	0.2	-0.5	0.6	0.6	1.1	0.1	0.6	-0.6
Arm fat-free mass (right)	0.3	1.3	5.5	-1.6	-2.4	-0.3	-0.1	-1.5	-1.1	0.1	-0.9	-0.0	-0.7
Exposure to tobacco smoke outside home	0.3	0.3	0.9	0.5	0.6	0.3	-1.0	0.5	0.6	-0.9	0.2	0.4	0.2
Age at first live birth	0.3	0.5	1.5	0.5	0.2	0.5	1.2	0.3	0.7	0.9	0.9	0.6	0.8
Leg fat mass (right)	0.3	1.2	2.6	0.3	-0.3	-1.2	-1.5	-0.3	-1.4	-0.8	-1.3	-1.3	-1.6
Number of full sisters	0.3	0.4	0.9	0.2	-0.8	0.7	0.8	0.2	-0.5	0.7	0.6	1.0	0.7
Age at last live birth	0.3	0.4	1.7	-0.1	-1.1	0.4	1.3	0.1	0.5	0.5	0.2	0.4	0.1
Family relationship satisfaction	0.3	0.4	1.0	1.0	0.8	0.2	0.8	0.2	0.7	-0.1	0.5	0.3	0.8
Illnesses of father: Heart disease	0.3	0.4	0.9	0.5	0.9	0.6	0.8	-0.4	0.4	0.7	0.6	0.5	0.7
Friendships satisfaction	0.3	0.3	1.1	-0.5	-0.5	-0.0	1.0	-1.0	-0.7	-0.3	-0.3	-0.3	0.0
Arm fat mass (left)	0.3	1.0	1.9	0.0	-0.5	-1.1	-1.2	-0.5	-1.2	-1.0	-1.2	-1.2	-1.4
Mother’s age at death	0.3	0.3	0.7	-0.2	-0.1	-0.7	-0.8	-0.7	-0.5	0.3	-0.8	-0.8	-0.3
Medication: Blood pressure	0.3	0.6	1.7	1.3	1.2	-0.1	-0.7	1.3	0.4	0.6	-0.2	-0.6	-0.5
Ever smoked	0.3	0.5	1.5	-0.6	-0.8	-0.3	-0.7	-0.4	-1.2	1.1	-0.4	0.0	0.2
Leg fat percentage (left)	0.3	1.2	2.2	0.9	0.1	-1.2	-1.5	-0.2	-1.3	-0.8	-1.1	-1.3	-1.4
Unable to work because of sickness or disability	0.3	0.3	0.6	0.8	0.6	0.6	-0.1	0.6	0.6	0.6	0.8	0.5	0.2
Medication: Omeprazole (e.g. Zanprol)	0.3	0.3	1.3	-0.4	-0.6	0.2	-0.2	-0.2	-1.1	-0.6	0.1	0.1	-1.0
Arm predicted mass (left)	0.3	1.3	5.2	-1.9	-2.3	-0.4	-0.0	-1.2	-1.2	0.1	-0.9	-0.1	-0.6
Crohns Disease (2017)	0.2	0.4	2.5	-1.6	-0.6	0.5	-0.1	0.3	-0.2	-1.0	0.1	0.2	-0.3
Prostate Cancer	0.2	0.3	1.4	0.2	0.1	0.2	0.5	1.2	0.1	-0.9	0.1	0.3	0.3
Fasting Glucose	0.2	0.3	0.9	0.3	0.2	-0.9	-0.4	0.6	-0.3	-0.0	-0.3	-0.9	-0.0
Lupus	0.2	0.2	1.0	0.3	0.3	-0.8	0.1	0.4	-0.2	0.6	-0.3	-1.0	-0.0
Schizophrenia (2014)	0.2	0.5	0.9	0.7	-0.0	-0.9	-1.0	0.3	-0.9	0.5	-0.7	-0.9	0.1
Allergy or Eczema	0.2	0.6	2.4	0.7	0.6	0.1	1.5	1.2	-0.2	-0.6	0.0	0.4	1.0
Systolic blood pressure, automated reading	0.2	0.7	2.6	-1.1	-1.6	-0.2	-0.5	-0.4	-1.1	-0.5	-0.9	-0.6	-0.4
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	0.4	-0.3	0.0	0.7	0.1	0.6	0.5	0.6	-0.1	0.5	0.1
Angina	0.2	0.3	0.8	-0.6	-0.5	-0.8	-0.8	-0.2	-0.5	-0.1	-0.5	-0.4	-0.9
Supplements: Zinc	0.2	0.2	1.1	-1.1	-0.3	-0.4	0.3	-0.3	-0.3	0.6	-0.4	-0.2	0.5
Medication: Metformin	0.2	0.3	0.7	-0.3	0.0	-0.5	-0.7	0.1	-0.6	-0.0	-0.7	-0.9	-0.8
Severe depression (siblings)	0.2	0.2	0.9	-0.3	0.2	-0.2	-0.7	0.9	-0.1	-0.4	-0.4	-0.4	0.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.3	0.7	0.5	0.1	0.1	-0.6	-0.8	-0.8	-0.8	-0.3	-0.5	0.4
Age when periods started (menarche)	0.2	0.5	2.7	-0.3	-0.7	1.0	0.6	-0.7	0.1	0.2	-0.0	0.4	1.6
Qualifications: CSEs or equivalent	0.2	0.3	1.4	0.1	0.2	0.4	0.5	-0.6	0.3	1.2	0.4	0.5	0.7
Waist circumference	0.2	0.6	2.2	0.1	-0.3	-0.7	-1.1	-0.0	-0.9	-0.2	-1.5	-0.8	-0.9
Number of incorrect matches in round	0.2	0.4	1.1	0.4	-0.2	0.7	-0.7	-0.9	0.2	1.0	0.3	0.5	-0.1
Hearing difficulty/problems with background noise	0.2	0.4	0.8	-0.9	-0.7	-0.2	-0.5	-0.1	-0.7	-0.4	-0.7	-0.4	-0.9
Financial difficulties in last 2 years	0.2	0.2	1.1	0.6	0.2	0.3	0.8	1.0	0.1	0.2	0.1	-0.1	-0.4
Diabetes (self-reported)	0.2	0.3	1.1	0.5	0.7	-0.6	0.2	1.0	0.2	0.6	-0.5	-0.4	-0.4
Arm fat percentage (right)	0.2	0.9	1.8	0.8	0.5	-0.9	-1.3	0.4	-0.9	-0.9	-0.9	-1.1	-1.1
Hip circumference	0.2	1.0	2.0	0.2	-0.2	-0.9	-1.4	-0.5	-1.0	-0.9	-1.4	-1.0	-1.2
Pulse rate	0.2	0.3	1.0	-1.0	-1.0	0.5	0.1	-0.2	-0.3	0.5	-0.3	0.2	-0.0
Happiness	0.2	0.3	1.1	-0.0	-0.2	-0.3	1.0	-0.4	0.1	-0.0	-0.1	-0.3	1.1
Qualifications: A levels/AS levels or equivalent	0.2	0.4	1.1	-0.6	-1.0	0.7	0.9	-1.0	-0.3	-0.3	0.3	0.6	-0.2
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	0.5	-0.1	-0.2	-0.1	-0.7	-0.7	0.7	0.6	-0.2	0.2	-0.2
Arm fat mass (right)	0.2	0.7	1.5	-0.1	-0.5	-0.9	-0.9	-0.2	-1.2	-0.8	-1.0	-0.9	-1.2
Length of working week for main job	0.2	0.2	1.8	-0.3	-0.0	-0.4	0.1	0.2	0.2	1.3	0.2	-0.0	0.2
Pulse wave reflection index	0.2	0.3	0.9	0.4	0.5	0.6	-0.6	0.0	-0.3	-0.0	0.5	0.6	-0.9
Mouth/teeth dental problems: Bleeding gums	0.2	0.3	1.2	-0.2	-0.3	0.4	1.0	0.4	0.1	-1.1	0.1	-0.1	0.8
Birth weight	0.2	0.4	1.1	0.3	-0.1	-1.0	0.1	0.8	-0.5	0.3	-0.5	-0.9	-0.6
Leg fat percentage (right)	0.2	0.9	1.8	1.0	0.5	-0.9	-1.4	0.2	-1.0	-0.6	-0.9	-1.0	-1.2
Health satisfaction	0.2	0.3	1.5	1.2	0.2	0.5	-0.1	0.8	0.2	0.3	0.1	0.4	0.1
Emphysema/chronic bronchitis	0.2	0.3	0.6	0.5	0.0	0.6	0.6	-0.1	0.4	0.8	0.2	0.5	0.7
Medication: Seretide 50 evohaler	0.2	0.3	0.8	0.0	-0.7	-0.6	0.9	-0.0	-0.9	-0.3	-0.2	0.2	-0.0
Arm predicted mass (right)	0.2	1.1	4.7	-1.4	-2.2	-0.3	0.0	-1.4	-1.0	0.0	-0.7	-0.1	-0.5
Alcohol intake frequency.	0.2	0.5	1.7	0.2	0.4	-0.9	-0.2	1.3	0.2	-1.2	-0.3	-0.6	-0.3
Knee pain experienced in last month	0.2	0.3	0.6	0.5	0.5	0.2	-0.8	0.5	-0.5	-0.7	-0.4	-0.4	-0.7
Whole body fat-free mass	0.2	1.1	4.5	-1.6	-2.1	-0.4	0.1	-1.0	-1.1	-0.1	-0.9	-0.0	-0.6
Arm fat percentage (left)	0.2	0.9	1.9	1.0	0.6	-1.0	-1.4	0.3	-0.8	-0.9	-1.0	-1.1	-1.1
Whole body water mass	0.2	0.9	4.3	-1.6	-2.1	-0.3	0.2	-0.8	-1.0	-0.0	-0.8	0.1	-0.5
Supplements: Fish oil (including cod liver oil)	0.2	0.2	0.8	-0.0	0.1	0.2	-0.8	0.9	0.3	-0.6	0.2	0.2	-0.3
Medication: Bendroflumethiazide	0.2	0.3	0.8	0.3	0.5	-0.6	-0.1	-0.2	0.5	0.9	-0.7	-0.7	-0.8
Medication: Paracetamol	0.2	0.3	1.2	0.4	0.8	-0.7	-0.1	1.1	0.4	0.1	-0.1	-0.8	-0.4
Basal metabolic rate	0.2	1.4	4.7	-1.6	-2.2	-0.7	-0.2	-1.1	-1.4	-0.4	-1.2	-0.4	-1.0
Arm fat-free mass (left)	0.2	1.2	4.7	-1.7	-2.2	-0.4	-0.1	-1.2	-1.2	0.0	-0.8	-0.1	-0.6
Ever had prostate specific antigen (PSA) test	0.2	0.2	0.6	-0.3	-0.8	-0.7	-0.3	0.4	-0.1	-0.3	-0.3	-0.7	-0.2
Vascular/heart problems diagnosed by doctor	0.2	0.6	2.9	-0.9	-0.6	-0.1	-0.4	-1.7	-0.3	-1.1	-0.6	0.1	0.4
Pain experienced in last month	0.2	0.4	1.4	0.7	0.1	0.5	-0.2	-1.2	0.2	0.8	0.4	0.5	0.7
Age at First Birth	0.1	0.2	0.7	-0.1	0.6	0.3	0.2	0.2	0.4	0.8	0.5	-0.0	0.1
LDL Cholesterol	0.1	0.2	0.6	-0.1	-0.5	0.6	-0.1	0.4	0.0	-0.8	0.3	0.6	-0.2
Primary Biliary Cirrhosis	0.1	0.1	0.5	0.2	0.0	-0.4	-0.5	-0.2	-0.3	-0.4	-0.3	-0.7	-0.2
Triglycerides	0.1	0.1	0.4	0.0	-0.6	-0.1	0.5	0.1	-0.1	0.5	0.1	-0.0	0.3
Blood Platelet Count	0.1	0.6	1.7	1.3	0.9	-0.3	-1.0	1.2	0.3	-0.1	-0.2	-0.8	0.5
Blood White Count	0.1	0.4	2.6	0.0	-0.5	-0.5	-0.6	-0.7	-0.4	1.6	-0.4	-0.2	0.2
Heel T-Score	0.1	0.6	2.9	0.3	0.4	-0.1	-1.6	0.5	-0.3	-1.7	-0.4	-0.4	0.5
BMI	0.1	0.7	2.1	1.1	0.4	1.1	0.8	1.0	0.2	0.2	0.8	1.4	0.4
Waist Hip Ratio (WHR)	0.1	0.3	1.0	-0.9	-0.9	-0.4	0.2	-0.2	-0.4	0.4	-1.0	-0.4	0.3
Systolic Blood Pressure	0.1	0.3	1.1	-0.4	-0.8	-0.2	1.1	0.8	0.1	0.1	-0.5	-0.3	0.4
Cardiovascular Disease	0.1	0.5	2.3	0.9	0.5	0.6	0.8	1.5	0.1	-0.2	0.5	-0.2	-0.2
Respiratory disease	0.1	0.1	0.5	0.6	-0.1	-0.5	0.7	-0.0	-0.3	0.0	-0.1	-0.2	0.1
Tanning	0.1	1.6	5.5	-0.2	-1.2	-1.2	-0.6	-2.4	-1.6	-0.8	-1.1	-0.7	-1.4
Medication for hormone replacement therapy	0.1	0.2	0.7	-0.1	-0.1	-0.1	-0.3	0.8	0.5	0.2	-0.5	-0.4	-0.1
Diabetes (mother)	0.1	0.2	0.5	-0.3	-0.4	-0.2	0.7	0.6	0.4	0.5	-0.2	0.2	0.0
Leg fat-free mass (left)	0.1	0.3	1.2	-0.6	-1.1	-0.2	-0.0	-0.2	-0.7	0.3	-0.7	-0.0	-0.6
Bilateral oophorectomy (both ovaries removed)	0.1	0.2	0.8	0.1	-0.4	0.9	0.2	0.2	0.4	0.4	0.1	0.5	-0.2
Diverticular disease/diverticulitis (self-reported)	0.1	0.1	0.2	-0.2	-0.3	0.4	-0.0	0.1	0.2	-0.2	0.4	0.4	-0.4
Body mass index (BMI)	0.1	0.5	2.0	1.4	0.9	0.4	0.3	1.1	0.1	0.6	0.1	0.4	0.1
Leg predicted mass (left)	0.1	0.3	1.2	-0.6	-1.1	-0.1	-0.0	-0.3	-0.7	0.3	-0.7	0.0	-0.6
Had menopause	0.1	0.2	0.6	0.5	0.2	0.3	-0.6	-0.3	0.2	0.3	-0.0	0.0	-0.8
Forced vital capacity (FVC)	0.1	0.2	1.0	-0.4	-0.9	-0.0	1.0	-0.5	-0.3	0.1	-0.2	0.1	-0.4
Medication: Simvastatin	0.1	0.1	0.8	0.9	0.4	-0.1	-0.1	-0.1	-0.0	0.4	0.1	-0.0	-0.4
Worrier / anxious feelings	0.1	0.1	0.6	0.4	0.1	0.1	0.0	-0.8	-0.1	-0.2	-0.2	-0.3	-0.8
Number of live births	0.1	0.2	1.2	0.1	-0.1	0.5	-1.1	-0.3	-0.2	-0.2	-0.5	-0.0	-0.4
Forced expiratory volume in 1-second (FEV1)	0.1	0.4	1.7	0.9	0.2	0.5	1.3	0.2	0.5	0.4	0.5	0.6	0.1
Asthma	0.1	0.2	0.5	-0.0	-0.2	-0.7	0.3	0.4	-0.5	-0.0	-0.5	-0.6	0.6
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.4	0.9	0.0	-0.6	-0.4	0.4	-0.6	-0.5	-0.7	-1.0	-0.5	-0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	0.1	0.2	0.5	-0.2	-0.2	-0.0	-0.2	0.0	-0.6	0.7	-0.5	-0.4	-0.5
Hair/balding pattern: Pattern 4	0.1	0.2	0.7	0.5	0.6	-0.3	-0.2	-0.9	0.1	-0.0	0.0	-0.2	-0.8
Number of full brothers	0.1	0.1	0.3	0.6	0.5	0.2	-0.2	0.4	0.1	-0.3	0.2	0.0	-0.2
Worry too long after embarrassment	0.1	0.1	0.4	0.2	-0.3	0.0	0.7	-0.4	-0.3	0.2	0.0	-0.3	0.2
Wheeze or whistling in the chest in last year	0.1	0.2	0.3	-0.3	-0.1	-0.3	-0.4	0.5	-0.2	-0.5	-0.6	-0.6	-0.5
Qualifications: College or University degree	0.1	0.2	0.7	-0.2	-0.1	0.2	0.7	-0.8	0.1	-0.1	0.2	0.2	0.5
Eye problems/disorders: None of the above	0.1	0.1	0.7	0.2	-0.2	-0.3	-0.0	0.3	-0.3	-0.8	-0.5	-0.1	0.1
Migraine (self-reported)	0.1	0.1	0.5	-0.0	0.7	0.2	0.5	0.4	0.1	-0.3	0.5	0.2	-0.1
Had major operations	0.1	0.1	0.4	-0.4	-0.6	-0.1	0.0	0.3	-0.3	-0.0	-0.4	-0.2	-0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.2	0.8	-0.4	0.1	0.3	-0.9	-0.1	-0.6	-0.0	0.1	0.4	0.1
Leg fat-free mass (right)	0.1	0.4	1.6	-0.6	-1.3	-0.3	0.0	-0.5	-0.8	0.2	-0.8	-0.2	-0.6
Diabetes diagnosed by doctor	0.1	0.1	0.5	0.1	0.3	-0.0	-0.2	0.2	0.0	0.3	-0.5	0.0	-0.7
Ever had stillbirth, spontaneous miscarriage or termination	0.1	0.2	0.7	-0.2	0.1	0.1	-0.3	-0.6	-0.5	0.8	-0.4	-0.3	-0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.1	0.1	0.4	0.2	0.3	0.6	0.2	-0.1	-0.6	-0.6	0.2	0.2	-0.2
Asthma (self-reported)	0.1	0.2	0.5	-0.2	-0.3	-0.7	0.6	0.2	-0.5	0.3	-0.4	-0.4	0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.3	1.7	1.1	1.3	-0.1	0.2	-0.1	0.0	-0.1	0.3	-0.2	-0.0
Leg predicted mass (right)	0.1	0.3	1.4	-0.5	-1.2	-0.2	0.1	-0.4	-0.7	0.3	-0.7	-0.0	-0.5
Miserableness	0.1	0.1	0.4	-0.1	0.6	0.3	-0.0	0.3	0.4	0.6	0.2	-0.0	0.5
Pain type(s) experienced in last month: Hip pain	0.1	0.2	0.6	-0.2	0.2	0.4	-0.5	-0.6	0.8	0.5	0.2	0.4	-0.1
High cholesterol (Self-reported)	0.1	0.2	0.6	0.1	-0.2	0.6	-0.6	-0.8	-0.4	-0.4	-0.6	-0.0	-0.2
Diastolic blood pressure, automated reading	0.1	0.3	0.9	0.2	-0.3	0.5	1.0	0.6	-0.2	0.3	0.4	0.3	0.6
Basal cell carcinoma (self-reported)	0.1	0.2	1.0	0.1	0.2	-0.2	0.6	0.2	1.0	-0.6	0.1	0.2	-0.1
Blood Eosinophil Count	0.0	0.2	0.8	0.6	0.3	0.1	0.0	0.9	0.4	0.1	0.2	-0.1	0.1
Blood Red Count	0.0	0.2	1.0	-0.3	-0.1	0.6	0.3	-0.5	0.0	-0.5	0.6	1.0	0.1
Hair Pigment	0.0	1.3	3.2	-0.3	-0.4	-1.0	-1.6	-1.0	-0.9	-0.9	-1.0	-1.5	-1.8
Pulse rate, automated reading	0.0	0.2	0.5	0.2	0.1	0.2	0.3	0.3	0.0	0.7	-0.4	-0.5	0.6

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