Hub : Genes

DTWD1

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0830	0.0360	3.7e-04	0.054	0.031	0.024	0.037	0.037	3.3e-07	9.3e-05	5.0e-04	2.1e-05	2.4e-05
2	GTEx	Cells Transformed fibroblasts	0.1460	0.0440	3.8e-07	0.075	NA	0.108	NA	0.122	2.8e-06	NA	1.9e-08	NA	2.0e-09
3	GTEx	Thyroid	0.0940	0.0360	2.9e-04	0.035	NA	0.020	NA	0.011	9.7e-04	NA	9.9e-03	NA	4.2e-02
4	NTR	Blood	0.0255	0.0089	3.9e-06	0.028	0.019	0.025	0.022	0.026	2.2e-09	4.6e-07	1.3e-08	1.1e-07	8.3e-09
5	TCGA	Bladder Urothelial Carcinoma	0.0380	0.0230	2.7e-03	0.036	0.036	0.040	NA	0.032	5.1e-04	4.8e-04	2.4e-04	NA	9.9e-04
6	TCGA	Breast Invasive Carcinoma	0.0585	0.0223	2.5e-09	0.041	0.048	0.051	NA	0.050	5.9e-09	3.7e-10	1.1e-10	NA	1.4e-10
7	TCGA	Colon Adenocarcinoma	0.1680	0.0630	1.6e-06	0.103	0.077	0.068	NA	0.073	1.6e-06	3.1e-05	8.9e-05	NA	4.9e-05
8	TCGA	Head and Neck Squamous Cell Carcinoma	0.0578	0.0255	2.2e-06	0.076	0.054	0.071	NA	0.073	6.2e-09	1.1e-06	2.2e-08	NA	1.3e-08
9	TCGA	Kidney Renal Clear Cell Carcinoma	0.1202	0.0473	1.7e-12	0.086	0.095	0.095	NA	0.126	6.2e-10	7.8e-11	7.5e-11	NA	5.5e-14
10	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0750	0.0440	7.9e-03	0.045	0.034	0.034	NA	0.031	1.4e-03	4.6e-03	4.9e-03	NA	6.8e-03
11	TCGA	Brain Lower Grade Glioma	0.0224	0.0130	4.9e-03	0.031	0.016	0.007	NA	0.023	1.7e-04	6.0e-03	4.2e-02	NA	1.1e-03
12	TCGA	Lung Adenocarcinoma	0.0563	0.0254	7.9e-06	0.022	0.049	0.037	NA	0.043	1.3e-03	1.8e-06	3.7e-05	NA	9.0e-06
13	TCGA	Lung Squamous Cell Carcinoma	0.0438	0.0226	1.6e-04	0.036	0.034	0.018	NA	0.024	5.0e-05	9.5e-05	3.4e-03	NA	8.1e-04
14	TCGA	Ovarian Serous Cystadenocarcinoma	0.0320	0.0180	5.9e-03	0.011	0.025	0.011	NA	0.012	5.9e-02	8.1e-03	5.3e-02	NA	4.8e-02
15	TCGA	Pheochromocytoma and Paraganglioma	0.1230	0.0690	6.1e-03	0.046	0.004	-0.005	NA	0.018	6.3e-03	2.1e-01	5.5e-01	NA	6.3e-02
16	TCGA	Prostate Adenocarcinoma	0.1588	0.0661	2.0e-10	0.121	0.096	0.108	NA	0.119	1.2e-12	3.2e-10	2.2e-11	NA	2.2e-12
17	TCGA	Stomach Adenocarcinoma	0.0910	0.0370	8.0e-07	0.083	0.078	0.064	NA	0.074	1.2e-06	2.6e-06	2.2e-05	NA	5.1e-06
18	TCGA	Testicular Germ Cell Tumors	0.2610	0.1050	1.3e-03	0.066	0.048	0.126	NA	0.130	2.3e-03	8.8e-03	3.4e-05	NA	2.5e-05
19	TCGA	Thyroid Carcinoma	0.1320	0.0590	1.5e-09	0.076	0.106	0.099	NA	0.119	6.7e-08	1.8e-10	7.1e-10	NA	1.3e-11

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19
Bipolar Disorder (2018)	0.4	0.6	2.2	0.3	1.5	-0.6	-1.1	0.4	1.2	1.3	0.6	0.1	0.9	0.8	0.4	0.4	0.3	0.6	0.8	0.3	-0.8	0.2
Bipolar Disorder or Schizophrenia	1.0	2.4	6.0	-1.7	-0.4	2.2	0.3	-1.7	-0.8	0.1	-1.3	-2.1	-0.6	-1.2	-1.6	-1.1	-2.3	-1.5	-1.3	-2.4	-1.8	-2.0
Depressed Affect (Nagel 2018)	2.7	5.6	9.1	-2.0	-1.5	2.6	1.9	-3.0	-2.1	-0.8	-3.0	-2.3	-2.8	-2.8	-1.9	-2.3	-2.6	-2.8	-2.7	-2.5	-2.1	-2.4
Depression (Nagel 2018)	1.6	2.4	4.1	-1.5	-0.2	1.2	0.8	-1.8	-1.6	-1.6	-1.7	-1.6	-1.5	-1.7	-1.8	-1.7	-1.4	-1.9	-1.8	-0.9	-2.0	-1.5
Intelligence (Savage-Jansen 2018)	0.1	0.4	1.5	-0.9	0.4	-0.0	-0.7	0.7	0.1	-0.6	0.9	-0.1	1.1	0.5	-0.1	1.0	-0.2	0.4	0.4	-0.6	1.2	-0.2
Neuroticism (Nagel 2018)	1.7	3.9	6.3	-1.4	-1.5	2.2	2.4	-2.3	-2.5	-1.2	-2.4	-1.5	-2.5	-2.4	-1.4	-1.3	-1.8	-2.4	-2.5	-2.0	-1.2	-1.6
Schizophrenia (2018)	2.7	5.5	12.4	-2.4	-1.7	3.5	1.3	-2.5	-2.0	-0.8	-2.1	-2.7	-1.5	-2.2	-2.4	-1.6	-3.2	-2.5	-2.3	-3.5	-1.6	-2.8
Schizophrenia vs Biploar Disorder	0.6	0.8	4.4	0.4	0.2	0.3	0.1	1.0	-0.6	-0.1	1.1	0.6	1.0	0.7	0.7	2.1	0.3	0.6	0.5	-0.8	2.1	0.6
Worry (Nagel 2018)	4.1	8.6	13.8	-2.1	-1.6	3.0	3.2	-3.3	-3.5	-2.3	-3.5	-2.6	-3.6	-3.7	-2.5	-2.1	-2.8	-3.5	-3.7	-2.9	-1.8	-2.7
Alzheimer’s Disease (in mother)	0.6	0.7	2.0	0.3	0.8	-0.3	-1.4	1.2	1.0	-0.1	1.0	0.5	0.9	1.0	0.3	0.5	1.1	1.1	1.0	1.2	0.2	0.6
Alzheimer’s Disease (in father)	0.4	0.5	3.1	0.2	1.8	-1.0	0.3	0.4	-0.5	-1.3	0.3	0.6	0.3	0.0	-0.1	0.1	0.3	0.1	0.0	0.5	1.2	0.5
Alzheimer’s Disease (including proxy)	0.6	0.8	3.8	0.2	1.9	-1.1	-1.1	0.8	0.6	-0.7	0.6	0.6	0.7	0.7	-0.1	0.1	1.3	0.7	0.7	1.8	0.1	0.8
Crohns Disease (2017)	0.6	1.2	6.3	-0.1	-2.5	1.7	0.6	-1.2	-0.3	0.2	-1.1	-0.7	-0.6	-1.0	0.2	-1.0	-1.4	-0.9	-0.8	-1.2	1.5	-1.1
Irritable Bowel Disease (IBD)	1.1	2.6	11.9	-0.8	-1.9	3.4	0.7	-1.8	-0.7	0.3	-1.5	-1.6	-1.0	-1.4	-0.6	-1.3	-2.3	-1.5	-1.3	-2.4	0.2	-1.9
Ulcerative Colitis (UC)	0.8	1.5	9.1	-0.6	-0.4	3.0	0.5	-1.3	-0.4	0.8	-1.0	-1.3	-0.7	-0.9	-0.5	-0.8	-1.7	-1.0	-0.8	-2.0	-0.7	-1.4
Major Depression (MDD)	0.3	0.3	0.8	0.4	-0.6	-0.9	-0.1	0.6	-0.1	-0.1	0.9	0.6	0.8	0.7	-0.0	0.8	0.6	0.4	0.6	0.3	-0.3	0.8
Reaction Time	0.3	0.6	2.8	0.9	-0.2	-0.1	1.2	-0.3	-0.7	0.2	-0.6	0.8	-1.7	-0.3	0.6	-0.1	1.1	-0.1	-0.3	0.7	-1.3	0.9
Verbal and Numeric Reasoning (VNR)	1.7	4.0	8.2	1.1	1.2	-1.6	-1.7	2.6	1.9	1.2	2.8	1.8	2.9	2.5	1.6	2.2	1.6	2.4	2.5	1.2	2.2	1.9
Breast Cancer	0.5	1.2	6.3	1.1	-1.1	-1.1	2.5	-0.4	-1.6	-0.1	-0.5	1.1	-1.1	-0.6	1.1	0.5	0.2	-0.4	-0.6	-0.5	2.0	0.8
Ovarian Cancer	0.8	1.1	4.0	-0.4	-0.8	1.0	2.0	-1.1	-1.5	-0.1	-1.2	-0.6	-1.2	-1.3	-0.5	-0.3	-1.0	-1.2	-1.4	-1.1	0.1	-0.7
Prostate Cancer	0.2	0.2	1.3	0.4	0.4	0.7	0.9	-0.1	0.4	1.1	-0.4	0.3	-0.5	-0.2	0.7	-0.1	-0.1	0.1	-0.1	0.0	0.6	0.1
Age at First Birth	0.7	1.0	3.9	0.6	0.3	-0.7	-2.0	0.6	1.9	1.0	0.7	0.2	1.5	0.8	0.5	0.0	0.7	0.7	0.9	1.6	0.6	0.3
Bipolar Disorder (2011)	0.7	0.7	3.4	0.3	1.1	-0.4	-1.1	-0.1	1.5	0.8	-0.0	-0.1	0.2	0.3	-0.0	-1.2	0.5	0.0	0.4	1.5	-1.8	0.0
Body Mass Index (BMI) (2010)	0.7	1.0	1.9	1.4	0.8	-1.0	-0.8	1.0	0.9	0.4	1.1	0.9	1.2	1.0	1.0	0.9	0.9	0.9	1.0	1.0	1.4	0.8
Coronary Artery Disease (CAD)	1.9	2.2	5.7	1.1	1.1	-2.4	-1.7	1.4	1.7	0.8	1.6	1.1	1.7	1.7	1.2	0.9	1.7	1.5	1.7	2.0	0.4	1.4
Crohns Disease (2012)	0.3	0.5	3.7	0.4	-1.9	1.2	-0.0	-0.2	0.4	0.5	-0.2	0.0	0.2	-0.1	0.5	-0.3	-0.5	0.0	0.0	-0.4	1.6	-0.2
Mean Putamen Volume	1.0	1.1	2.5	0.6	1.2	-1.1	-0.5	1.0	0.6	0.9	1.3	1.0	1.3	1.2	1.3	1.4	0.7	1.0	1.2	0.1	1.6	1.0
Fasting Glucose	0.8	1.0	5.0	1.7	0.4	-0.7	2.2	-0.2	-1.9	-0.4	-0.3	0.9	-1.1	-0.5	0.6	0.5	0.4	-0.3	-0.5	-0.3	1.2	0.8
HbA1C	0.9	1.0	3.1	1.4	1.2	-1.8	1.4	0.2	-1.3	-1.3	0.1	1.1	-0.4	-0.1	0.6	0.5	0.9	-0.0	-0.2	0.5	1.5	1.0
HDL Cholesterol	0.4	0.7	2.5	-0.4	0.5	0.9	1.6	-0.9	-1.5	-0.2	-0.8	-0.4	-1.1	-0.8	-0.5	-0.3	-0.7	-0.9	-0.9	-1.2	-0.6	-0.4
LDL Cholesterol	1.3	2.1	6.7	-2.6	-1.8	1.1	-1.0	-1.2	-0.2	-1.8	-0.9	-1.9	-0.5	-1.1	-1.9	-1.5	-1.2	-1.3	-1.1	-0.6	-2.1	-1.7
Lupus	0.8	1.2	2.7	-0.7	-1.0	0.8	0.5	-1.2	-0.7	-1.0	-1.0	-1.4	-0.6	-1.3	-1.2	-1.6	-1.3	-1.4	-1.2	-0.4	-0.8	-1.4
Neuroticism (2016)	0.6	0.8	3.3	0.4	0.2	1.6	1.8	-1.2	-1.3	0.4	-1.0	0.1	-1.2	-0.9	0.4	-0.3	-0.4	-1.0	-0.9	-0.8	-0.5	-0.0
Primary Biliary Cirrhosis	1.3	1.9	12.1	0.5	0.3	-2.0	1.8	-0.6	-2.2	-3.5	-0.8	0.5	-1.5	-1.2	-0.5	-0.9	0.8	-1.1	-1.2	1.3	0.5	0.5
Rheumatoid Arthritis	0.8	1.1	4.2	2.1	0.3	-1.9	0.8	0.5	-0.7	-1.2	0.5	1.4	0.2	0.3	0.8	0.7	1.1	0.3	0.2	1.1	1.7	1.3
Schizophrenia (2014)	1.7	3.7	8.5	-1.2	-0.5	2.6	1.6	-2.2	-2.2	-1.0	-2.0	-2.0	-1.7	-2.1	-1.8	-1.1	-2.4	-2.2	-2.2	-2.9	-0.9	-2.0
Triglycerides	0.2	0.3	0.7	-0.8	-0.3	0.5	-0.1	-0.7	-0.2	-0.5	-0.5	-0.6	0.0	-0.5	-0.2	-0.8	-0.7	-0.7	-0.5	-0.3	0.7	-0.7
Type 2 Diabetes (T2D) (2012)	0.3	0.4	1.2	-0.2	-0.1	1.0	0.6	-0.5	-0.4	0.1	-0.7	-0.6	-0.9	-0.6	-0.1	-0.2	-0.9	-0.2	-0.4	-1.1	1.1	-0.7
Ulcerative Colitis	0.3	0.4	3.3	-0.4	-0.2	1.8	0.4	-0.4	-0.2	1.1	-0.2	-0.3	-0.2	-0.1	0.3	0.3	-0.7	-0.2	-0.1	-1.4	-0.1	-0.4
Blood Eosinophil Count	0.4	3.4	8.9	-3.0	-2.3	0.5	-3.0	-0.7	1.3	-1.7	-0.1	-2.6	1.0	-0.2	-2.6	-2.4	-1.9	-0.6	-0.1	-0.6	-2.3	-2.4
Blood Platelet Count	0.6	6.5	25.1	-1.6	-5.0	1.6	3.1	-2.9	-2.7	-1.6	-2.6	-1.5	-1.9	-2.9	-0.8	-2.1	-3.0	-2.9	-2.7	-2.6	2.2	-2.0
Blood Red Count	0.2	1.9	6.0	0.1	0.3	-1.0	-2.3	1.4	2.2	1.6	1.8	0.3	2.4	1.8	0.6	1.0	0.1	1.5	1.8	0.1	0.6	0.4
Blood White Count	0.4	3.0	12.0	-1.8	-3.5	0.5	-0.1	-1.7	-1.4	-2.8	-0.9	-1.7	-0.1	-1.2	-1.9	-2.1	-2.1	-1.8	-1.2	-1.4	0.3	-1.8
Heel T-Score	0.4	3.5	5.3	2.2	2.2	-1.6	-1.4	2.0	1.8	1.9	2.2	1.5	2.3	2.1	1.7	2.3	1.4	2.0	2.0	1.0	1.6	1.5
BMI	0.2	1.1	5.7	-0.8	-2.3	-2.0	-1.3	0.1	-0.2	-2.4	0.3	-0.3	0.1	0.2	-1.1	-1.1	0.4	0.0	0.2	0.8	-0.9	-0.1
Height	0.2	3.4	10.1	-1.0	1.3	0.6	-1.4	1.8	1.7	3.2	2.4	0.9	2.9	2.4	1.4	3.1	0.5	1.9	2.1	-0.8	0.4	1.1
Waist Hip Ratio (WHR)	0.3	1.4	5.7	2.4	1.1	-2.1	1.2	0.1	-0.9	-1.4	-0.1	1.5	-0.9	-0.1	0.7	0.0	1.6	0.1	-0.0	1.6	0.6	1.5
Systolic Blood Pressure	0.4	1.9	5.3	1.7	0.9	-1.4	0.6	1.5	0.0	0.9	1.5	1.9	1.2	1.2	1.4	2.3	1.5	1.2	1.1	0.9	1.6	1.9
Smoking Status	0.2	0.6	5.1	-0.5	0.6	-0.4	-0.2	-0.6	0.0	-1.3	-0.7	-0.1	-0.6	-0.5	-0.6	-2.2	-0.1	-0.4	-0.3	1.1	-0.0	-0.3
Allergy or Eczema	1.2	3.2	7.0	2.3	0.3	-0.9	0.5	2.1	0.5	1.9	1.7	2.4	0.7	1.6	2.3	2.6	2.2	2.0	1.6	1.1	2.0	2.4
Cardiovascular Disease	0.4	1.2	5.2	0.5	-0.4	-0.7	1.4	-0.8	-2.1	-2.3	-0.9	-0.1	-1.5	-1.3	-0.3	-0.4	-0.1	-1.1	-1.3	-0.3	1.1	-0.3
Hypothyroidism (self reported)	0.3	0.8	8.4	-0.4	-2.9	-0.1	-0.2	-0.6	-0.0	-1.0	-0.6	-0.3	-0.7	-0.4	-0.5	-1.4	-0.1	-0.4	-0.3	0.5	-0.6	-0.3
Respiratory disease	0.6	1.3	7.8	1.0	-0.1	-0.6	2.8	-0.1	-2.5	-0.9	-0.3	1.2	-1.3	-0.6	0.4	0.9	0.5	-0.5	-0.7	-0.6	1.2	1.1
Type 2 Diabetes (T2D) (2018)	1.3	2.5	17.0	3.0	0.7	-0.6	1.9	0.7	-0.8	0.5	0.6	2.0	0.2	0.3	2.1	1.5	0.9	0.6	0.4	0.3	4.1	1.6
Lung FEV1/FVC ratio	2.4	12.3	73.3	-0.9	0.6	1.4	-7.2	0.3	8.6	3.6	0.6	-1.1	3.1	2.1	0.1	-5.7	-0.3	2.0	3.1	4.7	-2.4	-1.1
Lung FVC	0.2	0.9	4.6	0.5	0.5	-0.8	-1.4	0.1	2.2	1.3	0.2	0.2	0.8	0.5	1.0	-1.1	0.3	0.6	0.9	1.6	0.6	0.0
Neuroticism	0.7	1.8	3.0	-1.3	-0.6	1.5	1.5	-1.4	-1.7	-0.8	-1.5	-1.0	-1.7	-1.4	-1.2	-0.7	-1.1	-1.5	-1.6	-1.5	-1.7	-0.9
Chronotype (morning person)	2.0	4.6	8.0	2.8	1.6	-2.5	0.1	2.1	1.3	2.3	1.9	2.8	1.4	1.9	2.5	2.6	2.5	2.1	1.9	2.0	1.4	2.8
Hair Pigment	0.0	0.5	1.4	0.6	-0.6	0.6	-0.3	-0.1	1.0	0.9	0.4	0.8	1.2	0.6	0.8	-0.8	0.3	0.2	0.7	1.2	0.6	0.7
Tanning	0.3	3.7	19.6	-1.9	2.0	-1.3	-4.4	0.8	2.6	-0.7	1.6	-1.4	2.7	1.6	-2.0	-1.2	-0.2	0.8	1.5	1.2	-3.0	-0.8
Hand grip strength (left)	0.1	0.2	1.4	0.6	-0.2	0.3	-0.0	-0.2	0.5	1.2	-0.1	0.0	0.2	0.0	0.8	0.1	-0.2	0.0	0.1	-0.2	0.6	-0.1
Number of treatments/medications taken	0.4	0.7	2.8	1.7	1.1	-0.2	1.6	-0.5	-1.0	0.2	-0.7	0.4	-1.2	-0.8	0.7	-0.2	0.0	-0.5	-0.6	-0.2	1.1	0.2
Average weekly spirits intake	1.4	1.7	4.9	-0.6	-0.5	-0.7	-2.2	1.3	2.1	1.6	1.6	0.4	2.0	1.8	0.2	0.3	0.6	1.5	1.8	1.1	-0.7	0.6
Sensitivity / hurt feelings	0.7	1.2	5.7	0.1	-0.7	0.2	2.0	-1.0	-2.4	-1.3	-0.8	-0.3	-1.0	-1.0	-1.0	0.2	-0.7	-1.3	-1.3	-1.4	-0.8	-0.2
Frequency of depressed mood in last 2 weeks	1.3	1.8	4.6	-1.2	0.3	0.5	0.7	-2.1	-1.0	-0.6	-1.6	-1.2	-1.3	-1.4	-1.2	-2.1	-1.2	-1.8	-1.4	-0.6	-2.1	-1.1
Hearing difficulty/problems: Yes	0.3	0.5	1.6	0.1	0.9	0.9	-0.5	0.8	0.3	0.7	0.9	0.5	0.7	0.8	0.7	1.3	0.3	0.8	0.7	-0.7	0.7	0.5
Relative age of first facial hair	2.3	4.8	11.4	1.9	1.3	-3.4	-1.3	2.3	1.8	1.1	2.3	2.5	2.1	2.3	1.8	1.7	2.7	2.3	2.3	2.9	1.0	2.7
Other serious medical condition/disability diagnosed by doctor	0.3	0.3	2.7	-0.8	-1.6	-0.4	0.4	-0.2	-0.4	-0.5	-0.4	0.1	-0.9	-0.3	-0.2	-0.6	0.2	-0.1	-0.2	0.3	-0.5	0.1
Ever used hormone-replacement therapy (HRT)	3.0	3.8	11.4	1.8	3.4	-1.1	-0.8	1.9	1.4	1.9	1.9	2.1	1.5	2.0	2.3	2.1	2.2	2.0	2.0	1.7	1.4	2.1
Ever had hysterectomy (womb removed)	3.0	3.4	6.1	1.7	1.6	-1.4	-1.2	2.2	1.7	1.1	2.1	1.9	2.0	2.0	1.8	1.6	1.8	2.1	2.0	1.9	2.5	1.8
Systolic blood pressure, automated reading	0.6	1.9	4.9	1.2	1.3	-1.1	-0.1	1.5	0.6	1.2	1.6	1.6	1.3	1.5	1.5	2.2	1.5	1.4	1.3	0.8	1.0	1.7
Eye problems/disorders: Diabetes related eye disease	0.4	0.5	2.3	0.8	0.8	-1.1	-0.1	0.4	0.1	-0.5	0.3	0.9	0.1	0.4	0.5	-0.0	1.1	0.4	0.4	1.5	0.2	1.0
Angina	0.3	0.4	1.6	0.9	0.6	-0.9	1.2	-0.3	-0.7	0.5	-0.3	0.8	-0.7	-0.2	0.8	0.1	0.7	-0.1	-0.2	0.5	0.3	0.7
Medication for hormone replacement therapy	4.1	4.5	8.0	1.9	1.7	-2.2	-0.9	2.3	1.4	2.3	2.1	2.4	1.6	2.2	2.6	2.7	2.8	2.3	2.1	2.2	1.3	2.4
Vitamin and mineral supplements	0.3	0.4	0.9	0.5	0.9	-0.8	-0.8	0.4	0.8	0.6	0.7	0.4	0.7	0.8	0.4	0.2	0.3	0.6	0.8	0.2	0.0	0.4
Supplements: Zinc	0.3	0.3	1.7	0.4	-1.0	-0.7	-0.8	0.5	0.5	-0.2	0.4	0.2	0.5	0.4	0.1	-0.1	0.7	0.4	0.4	1.3	0.0	0.2
Medication: Co-codamol	0.5	0.5	2.5	-0.3	0.7	0.2	-1.6	-0.1	1.1	-0.2	0.2	-0.3	0.5	0.3	-0.5	-1.4	0.1	0.1	0.5	1.1	-1.2	-0.2
Medication: Metformin	1.8	2.5	10.7	2.9	2.2	-0.5	2.9	0.4	-1.6	0.3	0.1	2.0	-0.6	-0.1	1.6	1.2	0.8	0.2	-0.1	0.0	3.3	1.7
Diabetes (father)	0.4	0.5	2.1	0.9	0.1	-1.5	-0.1	0.4	0.0	0.2	0.8	0.8	0.8	0.7	0.8	1.0	0.8	0.4	0.6	0.6	0.4	0.9
Diabetes (mother)	0.4	0.5	1.8	-1.2	-1.3	0.6	0.4	-0.0	-1.0	-1.3	-0.0	-0.4	-0.2	-0.2	-1.0	0.2	-0.5	-0.3	-0.4	-0.9	-0.4	-0.2
Severe depression (siblings)	1.1	1.3	5.0	0.7	-0.8	-1.1	2.2	-1.6	-1.3	-0.2	-1.5	0.7	-1.7	-1.2	0.6	-1.3	0.1	-1.2	-1.1	0.6	0.2	0.4
Pack years adult smoking proportion	2.5	3.9	7.2	1.0	1.1	-2.0	-2.6	2.6	2.3	1.0	2.6	1.3	2.7	2.5	1.1	1.9	1.6	2.5	2.4	1.5	1.2	1.5
Impedance of leg (right)	0.1	0.5	1.8	1.0	1.2	0.3	1.3	-0.9	-1.0	-0.4	-0.8	0.2	-0.9	-0.9	0.4	-0.2	-0.1	-0.9	-0.8	-0.1	0.3	0.1
Leg fat-free mass (left)	0.3	1.7	7.4	-1.3	-1.4	-0.3	-2.7	1.5	1.9	0.5	1.7	-0.3	2.1	1.6	-0.3	0.6	0.2	1.5	1.6	0.3	-0.2	-0.0
Trunk fat percentage	0.2	0.6	2.6	-0.9	-1.6	-0.0	-0.8	-0.3	0.0	-1.2	-0.4	-1.1	-0.3	-0.4	-1.0	-0.9	-0.4	-0.4	-0.4	-0.1	-1.0	-1.0
Hand grip strength (right)	0.1	0.2	1.5	0.2	-1.0	0.7	0.2	-0.5	0.3	1.2	-0.5	-0.3	-0.2	-0.3	0.5	-0.3	-0.4	-0.3	-0.2	-0.3	0.1	-0.4
Townsend deprivation index at recruitment	0.5	0.7	2.3	0.3	1.5	-0.8	0.2	-0.5	-0.6	-1.4	-0.2	0.3	-0.5	-0.1	-0.7	-1.5	0.5	-0.4	-0.1	1.2	-1.4	0.5
Current tobacco smoking	0.9	1.5	7.1	1.3	1.0	-2.3	-0.9	0.6	0.8	-1.1	0.7	1.3	0.8	0.8	0.4	-0.8	1.5	0.7	0.9	2.7	0.5	1.3
Average weekly fortified wine intake	0.2	0.3	1.6	-0.8	0.2	0.2	-0.1	0.1	-0.6	-1.3	0.0	-0.5	0.0	-0.2	-0.7	0.2	-0.5	-0.2	-0.3	-0.8	0.6	-0.5
Maternal smoking around birth	0.2	0.3	0.8	0.4	0.4	-0.6	0.8	-0.5	-0.5	-0.3	-0.6	0.0	-0.7	-0.5	-0.4	-0.5	0.0	-0.5	-0.5	0.3	-0.9	0.1
Fed-up feelings	1.3	2.4	5.7	0.0	-0.6	0.6	2.2	-2.0	-2.4	-1.5	-1.9	-0.7	-2.3	-1.9	-1.0	-1.5	-0.8	-2.0	-1.9	-0.9	-1.4	-0.7
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.4	2.5	-0.6	0.7	-1.0	-0.7	0.1	-0.6	-1.6	0.4	-0.3	0.3	0.2	-0.8	-0.0	0.2	-0.1	0.0	0.2	-0.7	-0.1
Relative age voice broke	0.8	1.3	3.7	0.7	-0.6	-0.7	1.9	-1.1	-1.8	-1.9	-1.3	0.1	-1.4	-1.5	-0.7	-1.0	-0.2	-1.4	-1.5	0.4	0.1	0.0
Taking other prescription medications	1.1	1.7	6.6	0.1	-0.2	0.5	1.8	-1.7	-1.0	-0.0	-2.1	-0.4	-2.6	-1.7	-0.5	-2.2	-0.4	-1.4	-1.5	0.3	-1.4	-0.5
Age when periods started (menarche)	0.1	0.2	0.5	0.4	0.1	0.6	0.6	-0.5	-0.2	-0.4	-0.6	-0.2	-0.4	-0.5	-0.5	-0.7	-0.5	-0.5	-0.5	-0.1	0.0	-0.2
Bilateral oophorectomy (both ovaries removed)	1.8	2.1	5.5	2.3	-0.5	-0.8	-0.1	1.5	1.0	1.6	1.3	1.9	1.0	1.3	1.7	1.6	1.7	1.5	1.4	1.5	1.2	1.9
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.8	5.3	0.7	1.4	0.4	0.3	0.4	-0.3	0.7	0.4	-0.0	0.8	0.1	0.6	1.5	-0.6	0.2	0.1	-1.4	2.3	-0.3
Tinnitus: Yes, but not now, but have in the past	1.2	1.3	3.5	-0.4	0.5	-0.0	-1.8	0.9	1.7	1.9	1.2	0.5	1.3	1.5	1.2	0.7	0.8	1.3	1.5	0.6	0.0	0.6
Qualifications: CSEs or equivalent	1.5	2.0	5.4	-1.9	-1.2	0.4	-0.2	-1.7	-0.4	-1.5	-1.5	-1.7	-1.0	-1.3	-1.6	-2.3	-1.5	-1.5	-1.2	-0.7	-1.7	-1.6
Serious illness, injury or assault to yourself	1.3	1.6	3.7	-0.2	0.7	-0.6	-1.5	1.4	1.8	1.9	1.5	0.8	1.6	1.5	1.2	1.1	1.1	1.5	1.6	1.2	0.2	0.9
High blood pressure	0.8	2.1	7.5	1.6	-0.4	-0.2	2.7	-1.0	-2.6	-1.9	-1.4	0.2	-1.9	-1.7	-0.1	-0.3	-0.4	-1.3	-1.7	-0.7	2.0	-0.1
Hayfever, allergic rhinitis or eczema	0.7	1.5	7.6	1.4	-0.3	-0.0	1.0	1.5	-0.6	1.2	1.1	1.4	0.3	0.9	1.3	2.8	0.9	1.1	0.7	-0.8	1.6	1.4
Multivitamins +/- minerals	0.3	0.3	1.2	-1.0	-0.7	0.8	-0.7	-0.0	0.7	0.1	-0.0	-0.4	0.3	0.1	-0.7	-0.9	-0.2	0.0	0.1	0.5	-1.1	-0.3
Stomach or abdominal pain in last month	0.5	0.6	2.8	0.6	0.3	-0.0	1.7	-1.0	-1.4	-0.1	-0.9	0.1	-1.2	-0.8	0.0	-0.3	-0.4	-0.9	-0.9	-0.8	-0.3	0.1
Supplements: Glucosamine	0.6	0.8	4.3	-0.9	0.3	0.5	-2.1	0.0	1.7	1.2	0.6	-0.7	1.4	0.7	0.2	-0.2	-0.4	0.3	0.8	0.1	-0.4	-0.6
Diverticular disease/diverticulitis (self-reported)	0.2	0.2	0.5	-0.7	-0.3	-0.6	0.1	0.6	-0.1	-0.2	0.5	0.4	-0.0	0.5	-0.2	0.4	0.6	0.5	0.4	0.4	-0.5	0.6
Medication: Atenolol	1.1	1.3	4.7	2.2	0.5	-1.8	0.5	0.8	-0.5	-1.3	0.5	1.4	0.0	0.3	0.7	0.4	1.5	0.5	0.3	1.8	1.9	1.3
Medication: Levothyroxine sodium	0.4	0.7	3.7	-1.2	-1.9	1.7	-0.6	-0.3	0.7	0.6	-0.4	-0.6	-0.4	-0.1	-0.3	-0.9	-0.6	0.0	0.0	-0.5	-0.9	-0.6
Sitting height	0.2	1.6	5.7	0.2	0.0	0.8	-1.6	1.6	1.4	1.3	1.7	-0.0	2.4	1.3	0.6	2.1	-0.2	1.2	1.2	-0.6	1.8	-0.1
Chronic bronchitis/emphysema (father)	1.0	1.2	3.1	1.6	1.4	-1.6	1.8	0.3	-1.6	-0.8	0.0	1.3	-0.7	-0.1	0.8	1.2	1.2	-0.0	-0.3	0.4	1.1	1.2
High blood pressure (mother)	0.2	0.3	1.9	0.1	-0.5	0.8	0.4	-0.4	-0.1	0.4	-0.2	-0.3	0.1	-0.4	0.5	0.2	-0.8	-0.4	-0.3	-1.0	1.4	-0.5
Body mass index (BMI)	0.1	0.6	2.6	-1.0	-1.6	-0.8	-1.3	0.1	0.1	-1.4	0.1	-0.7	0.0	0.1	-1.0	-0.8	-0.0	0.0	0.1	0.3	-0.7	-0.6
Impedance of leg (left)	0.1	0.4	1.5	1.0	1.2	-0.1	1.2	-0.8	-0.7	-0.1	-0.7	0.4	-0.6	-0.7	0.4	-0.3	0.0	-0.7	-0.6	0.1	0.3	0.2
Leg predicted mass (left)	0.3	1.8	7.7	-1.3	-1.4	-0.4	-2.8	1.6	1.9	0.5	1.8	-0.2	2.2	1.7	-0.3	0.7	0.3	1.5	1.6	0.3	-0.2	0.0
Trunk fat mass	0.1	0.5	2.8	-1.1	-1.7	-0.3	-1.4	0.2	0.6	-0.8	0.2	-0.9	0.3	0.2	-0.8	-0.4	-0.1	0.2	0.2	0.2	-0.8	-0.7
Waist circumference	0.1	0.5	3.1	-0.6	-1.6	-1.1	-0.3	-0.1	-0.6	-1.8	-0.1	-0.2	-0.6	-0.1	-0.8	-0.6	0.4	-0.2	-0.2	0.4	-0.9	-0.0
Number of incorrect matches in round	1.2	1.9	12.4	-1.6	-1.2	0.9	0.6	-1.2	-1.1	-0.9	-1.3	-1.1	-1.9	-1.0	-1.6	-1.2	-0.5	-1.1	-1.1	-0.8	-3.5	-0.8
Past tobacco smoking	0.1	0.2	1.5	1.2	-0.2	-1.2	0.1	-0.0	-0.1	-0.2	0.1	0.4	0.1	0.0	0.4	0.6	0.6	-0.1	-0.0	0.5	-0.3	0.5
Alcohol usually taken with meals	0.3	0.4	2.1	-1.0	0.2	1.1	0.1	0.5	-0.2	0.6	0.5	-0.3	0.5	0.3	-0.5	1.3	-0.6	0.3	0.1	-1.5	-0.3	-0.2
Nervous feelings	0.8	1.5	6.0	0.4	-1.1	0.2	2.5	-1.3	-2.0	-0.9	-1.6	-0.1	-2.0	-1.6	-0.3	-0.3	-0.2	-1.4	-1.6	-0.4	-0.5	-0.1
Frequency of tenseness / restlessness in last 2 weeks	0.6	1.0	2.8	-0.2	-1.1	-0.1	1.6	-1.0	-1.7	-1.1	-1.1	-0.1	-1.6	-1.1	-0.7	-0.9	-0.2	-1.1	-1.1	-0.2	-0.9	-0.1
Hearing difficulty/problems with background noise	0.5	0.9	4.0	1.1	1.4	0.7	0.5	0.8	-0.4	0.9	0.7	0.9	0.2	0.5	1.3	2.0	0.7	0.7	0.4	-0.5	1.4	0.8
Hair/balding pattern: Pattern 2	3.0	3.8	7.9	0.6	-1.6	2.2	2.8	-2.6	-1.9	-0.7	-2.7	-0.8	-2.5	-2.6	-0.2	-2.2	-1.8	-2.4	-2.3	-1.3	0.9	-1.3
Had menopause	1.0	1.3	4.7	1.1	2.0	-0.1	0.9	1.1	-0.5	1.0	0.8	1.4	-0.2	0.8	1.0	2.2	1.6	1.0	0.6	0.4	-0.3	1.6
Had other major operations	1.7	2.1	5.4	-0.2	1.7	-0.0	-2.2	2.3	1.7	0.4	2.1	0.3	2.2	1.8	-0.2	1.5	0.4	2.0	1.7	0.1	0.9	0.4
Forced vital capacity (FVC)	0.7	2.6	7.9	1.2	0.4	-1.2	-2.0	1.3	2.8	2.0	1.4	1.0	2.1	1.6	1.8	0.5	1.1	1.6	1.8	2.0	1.8	0.8
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.8	2.6	-0.7	-0.6	1.5	-0.5	-0.3	-0.1	-0.3	-0.2	-1.3	0.5	-0.5	-0.9	-0.1	-1.6	-0.5	-0.5	-1.5	0.7	-1.5
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	3.1	0.6	1.7	0.3	1.1	-0.7	-0.7	0.2	-0.7	0.2	-1.0	-0.6	0.5	-0.3	0.0	-0.5	-0.5	-0.2	0.1	0.1
Qualifications: None of the above	0.2	0.4	1.1	1.0	0.7	-1.0	0.5	-0.7	-0.1	0.0	-0.5	0.5	-0.6	-0.3	0.5	-0.9	0.5	-0.4	-0.2	1.0	-0.5	0.5
Financial difficulties in last 2 years	1.4	1.8	6.3	-1.0	-0.4	0.2	0.7	-1.7	-1.1	-1.8	-1.5	-1.0	-1.5	-1.4	-1.6	-2.5	-0.9	-1.5	-1.3	-0.0	-1.9	-1.0
Mouth/teeth dental problems	1.4	2.1	11.5	-1.6	0.5	0.7	-3.4	0.4	2.0	-0.1	1.0	-1.9	2.5	0.8	-1.3	-0.4	-1.7	0.4	0.8	-0.9	0.2	-1.9
Heart attack	0.5	0.6	2.2	-1.5	-0.4	-0.4	-1.2	-0.5	0.1	-1.0	-0.1	-1.1	0.3	-0.0	-1.0	-1.0	-0.6	-0.4	-0.0	-0.2	-1.1	-0.9
Allergy	0.5	1.1	4.6	-1.3	0.0	0.3	-1.9	-0.5	1.9	-0.1	-0.3	-1.1	0.5	-0.0	-0.9	-2.1	-0.6	-0.1	0.2	1.0	-1.6	-1.0
Pain all over the body in last month	3.0	3.2	7.5	0.8	1.6	-2.7	-1.3	2.0	1.1	0.7	2.4	1.7	2.2	2.2	1.0	2.5	1.9	1.8	2.0	1.3	0.1	2.0
Diabetes (self-reported)	0.7	1.1	6.5	1.7	0.0	-0.5	1.8	0.3	-1.6	-0.8	0.2	1.2	-0.3	-0.1	0.7	0.9	0.4	0.0	-0.1	-0.3	2.6	1.0
Hayfever/allergic rhinitis (self-reported)	0.2	0.2	1.0	-0.1	-0.4	0.8	0.9	0.2	-1.0	-0.3	0.1	0.3	-0.3	-0.0	-0.2	0.7	-0.1	0.0	-0.2	-0.8	0.4	0.3
Medication: Ramipril	0.4	0.5	3.5	1.9	0.7	-0.5	0.3	0.1	-0.1	0.3	0.2	0.8	0.2	0.1	0.9	0.3	0.7	0.1	0.2	0.9	0.8	0.7
Medication: Simvastatin	0.7	1.1	3.2	1.8	0.2	-1.7	0.6	0.7	-0.0	0.1	0.5	1.5	0.1	0.5	1.3	0.5	1.4	0.6	0.5	1.6	1.3	1.4
Fluid intelligence score	2.5	5.2	12.9	0.6	1.5	-1.6	-2.6	2.5	2.7	1.9	3.1	1.8	3.6	3.1	1.8	2.0	1.5	2.6	3.0	1.3	1.7	1.9
Illnesses of siblings	0.5	0.7	4.8	-0.7	-1.0	0.8	-0.4	-0.8	0.8	0.1	-0.9	-0.5	-0.6	-0.4	-0.6	-2.2	-0.4	-0.4	-0.2	0.7	-1.5	-0.5
Neuroticism score	0.9	1.9	4.9	-0.8	-0.5	1.2	1.9	-1.7	-2.2	-0.7	-1.4	-0.9	-1.7	-1.5	-0.9	-0.2	-1.1	-1.8	-1.7	-1.9	-1.5	-0.8
Weight	0.2	0.9	4.5	-1.4	-1.8	-0.4	-2.1	0.7	1.1	-0.3	0.8	-0.7	1.1	0.8	-0.7	-0.1	-0.0	0.7	0.8	0.2	-0.8	-0.5
Impedance of arm (right)	0.5	2.4	6.9	-0.9	-0.7	2.6	1.4	-1.8	-1.1	-0.9	-1.9	-1.5	-1.5	-1.9	-1.1	-1.4	-1.8	-1.8	-1.8	-1.4	-0.2	-1.7
Arm fat percentage (right)	0.4	1.7	6.7	-1.5	-2.6	0.6	-0.6	-0.8	-0.4	-1.9	-1.0	-1.7	-0.9	-1.0	-1.7	-1.6	-1.0	-0.9	-1.0	-0.4	-1.1	-1.6
Trunk fat-free mass	0.7	3.7	9.9	-0.5	-0.6	-1.2	-3.1	2.4	2.8	1.5	2.6	0.8	3.0	2.6	0.7	1.6	1.3	2.4	2.6	1.2	0.3	1.1
Hip circumference	0.2	0.9	4.6	-2.0	-2.1	0.2	-1.2	-0.2	0.1	-0.9	-0.1	-1.2	0.2	-0.1	-1.1	-0.6	-0.7	-0.3	-0.2	-0.5	-0.9	-1.0
Time employed in main current job	0.6	0.7	3.1	1.1	0.5	-0.2	0.5	0.3	0.4	1.8	0.4	1.2	0.0	0.7	1.4	0.7	1.0	0.7	0.7	0.6	-0.1	1.2
Alcohol intake versus 10 years previously	0.6	0.9	4.7	-0.8	-1.4	0.9	0.0	-1.3	-0.3	-0.9	-1.0	-0.9	-0.6	-0.9	-0.7	-2.2	-0.9	-1.0	-0.7	-0.0	-0.3	-1.0
Father’s age at death	0.5	0.7	1.9	1.4	0.1	-0.1	1.1	-1.0	-1.0	-0.9	-1.1	-0.2	-1.1	-1.1	-0.1	-0.8	-0.2	-1.0	-1.0	0.2	0.3	-0.4
Worrier / anxious feelings	4.3	8.1	16.2	-1.7	-2.2	2.5	3.8	-3.2	-4.0	-2.3	-3.2	-2.0	-3.6	-3.4	-2.0	-1.3	-2.5	-3.4	-3.6	-3.4	-1.5	-2.1
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.7	3.0	0.5	0.1	0.1	1.7	-0.9	-1.6	-0.8	-0.9	0.3	-1.3	-0.9	-0.0	-0.7	-0.0	-0.9	-0.9	-0.1	0.2	0.2
Falls in the last year	0.3	0.4	1.9	-1.2	0.4	-0.4	-1.4	0.7	0.5	-0.3	0.9	0.0	0.8	0.9	-0.2	0.0	0.3	0.7	0.9	0.2	-0.4	0.2
Hair/balding pattern: Pattern 3	0.2	0.3	1.0	-0.9	-0.5	-0.5	-0.2	0.8	-0.1	-0.7	0.5	0.3	0.2	0.4	-0.3	1.0	0.8	0.5	0.2	0.5	-0.4	0.5
Number of live births	0.3	0.4	1.5	-0.4	-0.6	-0.5	0.6	-0.2	-0.5	-0.5	-0.8	-0.5	-1.2	-0.8	-0.6	-0.2	0.1	-0.4	-0.8	0.3	-0.8	-0.5
Forced expiratory volume in 1-second (FEV1)	0.9	3.1	16.1	0.9	0.2	-0.6	-3.0	1.1	4.0	2.2	1.2	0.4	2.4	1.6	1.4	-0.8	0.6	1.6	2.0	2.4	1.2	0.3
Pulse rate	0.2	0.3	2.2	0.3	-0.1	0.1	1.5	-0.3	-0.9	0.2	-0.6	0.2	-1.1	-0.6	0.0	0.5	0.2	-0.4	-0.6	-0.3	-0.6	0.3
Happiness	6.2	7.5	13.4	-0.9	-1.2	2.2	2.9	-3.4	-3.2	-2.7	-3.6	-2.2	-3.7	-3.7	-1.9	-2.9	-2.4	-3.4	-3.5	-2.1	-0.8	-2.5
Noisy workplace	1.3	1.6	5.0	1.7	-0.5	0.4	2.2	-1.7	-1.6	-0.0	-1.7	-0.1	-1.7	-1.6	0.8	-0.4	-0.6	-1.5	-1.5	-0.8	1.2	-0.4
Qualifications: A levels/AS levels or equivalent	0.1	0.3	1.9	0.3	0.4	0.1	-0.8	0.4	0.9	0.1	0.3	-0.3	0.8	0.2	0.1	0.2	-0.3	0.3	0.3	0.1	1.4	-0.5
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.5	3.1	0.7	1.8	-0.5	-0.6	0.8	0.8	0.0	0.5	0.4	0.6	0.5	0.1	0.2	0.6	0.7	0.5	1.0	0.3	0.4
Mouth/teeth dental problems: Dentures	0.6	1.1	2.6	0.1	-1.5	-0.3	0.2	1.0	0.8	1.3	0.6	1.5	-0.1	0.8	1.2	0.6	1.6	1.2	0.9	1.5	0.1	1.5
Asthma	1.0	1.9	9.3	-0.5	0.0	1.0	2.5	-1.1	-3.0	-1.2	-1.0	-0.4	-1.6	-1.3	-0.6	0.4	-1.1	-1.4	-1.5	-2.4	0.5	-0.5
Medication: Ibuprofen (e.g. Nurofen)	1.0	1.3	4.5	-1.2	-0.6	1.9	0.6	-1.0	-0.8	0.0	-0.8	-1.3	-0.7	-0.8	-1.0	-0.4	-1.6	-1.0	-0.9	-2.1	-1.2	-1.2
Medication: Cholesterol lowering	0.7	1.1	2.9	1.7	0.9	-1.5	0.2	1.4	0.3	-0.4	0.7	1.3	0.0	0.6	0.6	0.9	1.5	1.1	0.6	1.5	1.2	1.3
Depression (self-reported)	3.5	4.2	15.0	0.3	-0.8	1.5	3.9	-2.2	-2.8	-1.2	-2.8	-0.5	-3.4	-2.8	-1.1	-1.6	-1.0	-2.3	-2.7	-0.8	-0.8	-0.7
Medication: Lansoprazole	1.2	1.3	2.6	1.6	1.6	-1.6	-0.1	0.9	0.5	0.7	0.9	1.4	0.6	1.0	1.3	0.9	1.6	1.0	1.0	1.6	0.6	1.5
Prospective memory result	0.8	1.0	2.7	1.0	-1.0	-1.1	1.6	-1.0	-1.4	-0.8	-1.2	0.2	-1.5	-1.2	0.4	-0.6	0.3	-1.0	-1.2	0.5	0.7	0.0
Lung cancer (father)	1.3	1.5	2.9	0.8	0.6	-1.5	-1.2	1.5	0.8	0.2	1.7	1.1	1.7	1.6	0.7	1.6	1.4	1.3	1.4	1.2	0.2	1.3
Illnesses of mother	0.7	0.9	3.2	0.1	-0.2	-1.8	-1.4	0.8	1.0	-0.2	1.0	0.7	1.2	1.1	0.1	-0.2	0.9	0.9	1.1	1.4	-0.1	0.8
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.2	8.5	0.5	-0.2	0.4	-1.9	-0.3	2.9	1.6	-0.3	-0.5	0.8	0.1	0.6	-1.8	-0.4	0.3	0.6	1.4	0.5	-0.8
Pulse wave Arterial Stiffness index	0.3	0.4	1.3	0.3	-0.3	1.0	0.3	0.5	-0.4	-0.7	-0.0	-0.5	-0.1	-0.4	-0.4	1.2	-0.5	0.0	-0.5	-1.1	1.1	-0.5
Impedance of arm (left)	0.5	2.4	5.0	-0.5	-0.5	2.2	1.8	-1.9	-1.5	-0.5	-2.0	-1.3	-1.7	-2.1	-0.7	-1.1	-1.7	-1.9	-2.0	-1.5	-0.1	-1.6
Arm fat mass (right)	0.2	0.8	3.9	-1.3	-2.0	0.0	-1.4	0.0	0.4	-1.2	-0.1	-1.1	0.0	-0.1	-1.1	-0.8	-0.4	-0.1	-0.1	-0.0	-0.8	-1.0
Trunk predicted mass	0.6	3.6	9.4	-0.6	-0.7	-1.2	-3.1	2.4	2.7	1.5	2.6	0.8	2.9	2.6	0.7	1.6	1.2	2.4	2.5	1.2	0.2	1.1
Standing height	0.2	2.3	7.0	-1.0	-0.3	0.8	-2.4	1.4	2.5	2.4	1.8	0.0	2.6	1.8	0.6	1.5	0.1	1.5	1.8	0.0	-0.0	0.2
Length of working week for main job	2.1	2.3	4.5	1.1	0.7	-2.1	-0.8	1.7	0.8	0.2	1.8	1.9	1.5	1.7	1.3	1.2	1.9	1.6	1.7	1.9	1.2	2.0
Exposure to tobacco smoke at home	0.3	0.4	2.4	-0.4	-0.7	-1.2	0.1	0.5	-0.4	-0.2	0.2	0.1	-0.4	0.2	-0.4	0.7	0.7	0.3	0.1	0.0	-1.6	0.4
Breastfed as a baby	0.3	0.4	1.9	-0.8	1.4	1.1	-0.5	0.3	0.1	-0.0	0.1	-0.8	0.3	-0.1	-0.9	0.2	-0.7	0.1	-0.1	-0.7	-0.3	-0.7
Tense / ‘highly strung’	1.1	1.7	6.9	0.5	-0.0	0.8	2.6	-1.7	-2.2	-0.3	-1.7	-0.4	-1.9	-1.7	-0.1	-0.4	-0.8	-1.7	-1.7	-1.3	-0.1	-0.5
Seen doctor (GP) for nerves, anxiety, tension or depression	2.4	3.7	7.2	-1.2	-0.1	2.4	2.7	-2.5	-2.4	-0.6	-2.5	-1.2	-2.7	-2.3	-1.2	-1.6	-1.6	-2.3	-2.3	-1.7	-1.7	-1.3
Hair/balding pattern: Pattern 4	0.2	0.5	2.0	-0.3	-1.4	-0.8	-0.6	0.8	-0.1	-0.4	0.7	-0.3	0.6	0.3	-0.2	1.3	-0.2	0.4	0.2	-1.0	1.0	-0.3
Birth weight of first child	0.3	0.5	3.1	0.3	1.8	-0.2	-0.9	0.3	1.1	0.8	0.5	0.2	0.7	0.7	0.3	0.1	0.4	0.5	0.7	0.6	-0.6	0.3
Peak expiratory flow (PEF)	1.0	2.3	6.0	-2.0	-0.5	2.3	-1.8	-0.9	1.4	-0.2	-0.7	-2.3	0.7	-0.6	-1.8	-2.0	-2.5	-0.7	-0.4	-1.1	-0.5	-2.4
Pulse wave reflection index	0.7	0.8	2.7	-0.1	-0.8	1.0	1.0	-0.8	-1.1	-0.7	-0.8	-0.8	-0.8	-1.0	-0.8	-0.1	-1.2	-1.0	-1.1	-1.6	-0.4	-0.8
Ever highly irritable/argumentative for 2 days	0.8	0.9	2.2	1.0	1.4	-0.5	1.0	0.8	0.0	1.2	0.4	1.5	-0.2	0.5	1.4	1.1	1.0	0.8	0.5	0.4	1.3	1.4
Loud music exposure frequency	0.9	1.0	2.3	1.0	0.2	-1.0	0.3	0.8	0.5	1.5	0.8	1.5	0.5	1.0	1.5	0.7	1.0	1.0	1.0	0.7	1.1	1.4
Qualifications: O levels/GCSEs or equivalent	0.1	0.2	1.3	0.3	0.2	-0.1	0.4	-0.2	-0.3	-0.4	-0.1	-0.1	0.1	-0.3	0.0	0.1	-0.5	-0.3	-0.3	-0.6	1.1	-0.3
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	2.3	1.1	0.0	-0.5	1.5	0.3	-0.9	0.5	0.1	1.0	-0.6	0.1	0.7	1.2	0.7	0.2	-0.0	-0.3	0.1	1.0
Blood clot in the leg (DVT)	0.4	0.5	1.7	0.9	-1.3	-1.1	0.3	0.2	0.1	-0.1	0.2	0.8	0.2	0.1	0.8	0.3	0.8	0.2	0.2	1.1	0.9	0.7
Medication: Paracetamol	0.5	0.9	2.3	0.3	0.8	-0.1	1.1	-1.5	-1.5	-1.3	-0.9	-0.4	-0.8	-1.0	-0.4	-1.0	-0.9	-1.4	-1.0	-1.0	0.0	-0.5
Headache pain in last month	2.9	5.0	10.3	-1.1	-2.2	3.2	2.3	-2.5	-1.8	-1.0	-2.8	-1.9	-2.6	-2.6	-1.9	-2.6	-2.5	-2.4	-2.5	-2.0	-1.2	-2.1
Medication for cholesterol, blood pressure or diabetes	0.6	1.0	5.0	-1.6	-1.2	1.3	-0.6	-0.9	0.0	-0.1	-0.5	-1.3	-0.1	-0.4	-1.2	-0.9	-1.0	-0.8	-0.5	-0.7	-2.2	-1.0
Glaucoma (self-reported)	1.6	1.8	4.9	1.5	1.5	-2.2	0.4	1.5	0.3	0.5	0.8	1.8	0.2	0.7	1.5	1.9	1.8	1.2	0.7	1.4	1.8	1.6
Gout (self-reported)	0.8	1.0	6.0	0.3	0.0	0.6	2.4	-0.8	-1.9	-0.2	-1.1	0.2	-1.7	-1.1	-0.1	0.0	-0.4	-0.9	-1.2	-1.0	0.1	0.1
Hypothyroidism/myxoedema (self-reported)	0.2	0.5	6.4	-0.4	-2.5	0.0	-0.2	-0.2	0.2	-0.3	-0.4	-0.0	-0.6	-0.1	-0.2	-1.0	0.1	-0.0	-0.0	0.5	-0.5	-0.0
Medication: Amlodipine	0.3	0.4	3.1	0.5	0.3	-0.3	0.0	-0.1	-0.6	-1.8	-0.1	-0.4	0.2	-0.5	-0.8	-0.4	-0.6	-0.4	-0.5	-0.2	1.3	-0.5
Medication: Ventolin 100micrograms inhaler	0.4	0.5	2.3	0.5	-1.5	0.8	1.1	-0.5	-0.9	-0.0	-0.7	-0.2	-0.7	-0.8	-0.0	0.1	-0.6	-0.6	-0.8	-0.9	0.6	-0.4
Birth weight	3.3	7.2	27.6	-1.2	0.9	-1.7	-5.3	3.0	3.9	1.7	3.6	0.3	4.5	3.6	0.2	1.7	1.3	3.1	3.5	1.6	-0.8	0.8
Chronic bronchitis/emphysema (mother)	0.9	1.1	2.2	-0.6	-0.9	0.9	0.8	-1.3	-0.7	-0.6	-1.4	-0.9	-1.5	-1.3	-0.9	-1.3	-0.8	-1.2	-1.2	-0.5	-1.4	-0.9
High blood pressure (siblings)	0.1	0.2	0.8	0.0	-0.1	0.3	0.0	0.4	-0.3	-0.5	0.2	-0.4	0.4	-0.1	-0.4	0.9	-0.5	0.0	-0.2	-0.9	0.9	-0.5
Forced vital capacity (FVC), Best measure	0.2	0.6	2.7	0.9	-0.1	-0.1	-1.0	-0.0	1.7	1.1	-0.0	-0.1	0.8	0.1	0.9	-0.6	-0.1	0.2	0.4	0.9	1.3	-0.4
Body fat percentage	0.3	1.0	3.8	-0.9	-2.0	-0.1	-0.3	-0.8	-0.5	-1.6	-0.9	-1.2	-0.9	-0.9	-1.2	-1.3	-0.5	-0.8	-0.8	-0.1	-1.0	-1.1
Leg fat percentage (right)	0.2	0.6	3.8	-0.1	-2.0	-0.8	0.0	-0.5	-0.6	-1.3	-0.7	-0.4	-1.0	-0.7	-0.4	-0.9	0.1	-0.6	-0.6	0.3	-0.3	-0.4
Arm fat-free mass (right)	0.7	3.4	8.0	-0.3	-0.3	-1.5	-2.8	2.3	2.3	1.6	2.6	0.9	2.8	2.6	0.8	1.9	1.3	2.3	2.4	0.9	0.0	1.1
Exposure to tobacco smoke outside home	0.1	0.2	0.6	-0.5	-0.8	-0.8	0.1	0.4	-0.2	-0.4	0.1	0.1	-0.4	0.1	-0.4	0.2	0.4	0.3	0.0	0.2	-0.8	0.3
Comparative body size at age 10	1.0	2.6	12.0	-3.5	-1.7	-0.1	-2.9	0.1	1.0	-1.1	0.4	-2.3	1.2	0.2	-2.3	-0.9	-1.5	-0.1	0.1	-1.0	-1.9	-2.0
Number of full brothers	1.1	1.4	3.3	-0.8	-0.7	-0.0	1.0	-1.5	-1.8	-1.3	-1.3	-1.2	-1.4	-1.4	-1.0	-0.8	-0.9	-1.5	-1.5	-1.1	-1.1	-1.2
Worry too long after embarrassment	0.2	0.3	2.5	-0.6	-1.6	0.6	0.3	-0.2	-0.7	-0.7	-0.1	-0.3	-0.1	-0.3	-0.4	0.2	-0.4	-0.4	-0.4	-0.7	0.2	-0.3
Seen a psychiatrist for nerves, anxiety, tension or depression	6.6	8.6	15.9	-1.6	-0.3	3.0	3.6	-3.6	-3.8	-2.0	-3.7	-2.1	-4.0	-3.6	-2.1	-2.6	-2.7	-3.6	-3.6	-3.0	-1.7	-2.3
Wheeze or whistling in the chest in last year	0.9	1.6	7.7	-0.0	-0.4	0.7	2.6	-0.7	-2.8	-1.1	-0.9	0.0	-1.7	-1.3	-0.1	0.6	-0.7	-1.1	-1.4	-1.9	1.3	-0.2
Number of children fathered	0.4	0.5	2.2	-0.3	-1.5	-0.8	0.4	0.8	-1.0	-1.5	0.4	0.5	-0.4	0.2	-0.3	0.8	0.8	0.4	-0.0	0.3	0.2	0.6
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.5	3.3	0.7	1.8	-0.6	1.2	-0.6	-0.6	0.6	-0.5	0.6	-0.8	-0.4	0.8	-0.1	0.3	-0.4	-0.4	0.2	-0.1	0.5
Age at first live birth	0.2	0.4	2.6	-0.8	-0.3	1.6	-0.7	-0.3	0.8	0.7	-0.3	-0.7	0.0	-0.2	0.0	-0.6	-0.6	-0.1	-0.0	-0.3	0.1	-0.8
Pulse wave peak to peak time	0.4	0.5	1.7	-0.4	0.4	-1.1	-0.7	-0.2	0.8	0.8	0.3	0.5	0.5	0.6	0.5	-1.0	0.6	0.2	0.7	1.3	-0.9	0.6
Health satisfaction	0.6	0.8	3.3	0.6	0.9	-0.2	1.8	-1.0	-1.3	-0.8	-1.1	0.4	-1.5	-1.0	0.3	-0.8	-0.1	-0.9	-0.9	-0.1	0.7	0.2
Shortness of breath walking on level ground	1.0	1.1	4.7	0.4	-0.9	0.4	2.2	-1.1	-1.7	-0.6	-1.4	0.3	-2.0	-1.3	0.3	-0.6	-0.0	-1.0	-1.2	-0.4	0.5	0.1
Qualifications: College or University degree	0.2	0.8	3.3	-0.5	-0.3	-0.3	-0.3	1.4	-0.2	-0.5	1.4	0.7	1.0	1.0	0.2	1.8	0.6	1.0	0.8	-0.4	1.2	0.8
Eye problems/disorders: None of the above	0.3	0.4	1.7	0.2	-0.3	1.1	-0.7	0.2	1.3	1.1	0.2	0.2	0.6	0.5	0.8	-0.3	-0.2	0.5	0.6	0.1	0.9	-0.0
Mouth/teeth dental problems: Loose teeth	2.1	2.5	7.2	-0.3	-1.5	0.7	2.1	-1.8	-1.6	-2.0	-2.3	-0.4	-2.7	-2.1	-1.0	-2.3	-0.5	-1.7	-1.9	0.3	-0.8	-0.6
Emphysema/chronic bronchitis	0.5	0.6	2.5	-0.7	-0.3	0.5	1.6	-0.4	-1.6	-0.8	-0.6	-0.1	-1.0	-0.8	-0.6	0.2	-0.3	-0.7	-0.9	-0.7	0.0	-0.1
Medication for pain relief, constipation, heartburn	1.4	2.5	5.3	0.3	-0.2	-0.8	-1.7	1.9	2.3	2.0	1.7	1.3	1.7	1.9	1.5	1.3	1.5	2.0	2.0	1.6	0.8	1.3
Neck or shoulder pain in last month	0.4	0.6	1.6	1.0	0.4	-0.8	-0.3	0.4	0.6	1.2	0.6	0.9	0.6	0.7	1.3	0.3	0.9	0.6	0.8	1.0	0.7	0.8
Medication: Blood pressure	0.3	0.6	5.8	1.5	0.7	-0.1	0.9	0.2	-0.6	-0.2	-0.0	0.5	-0.2	-0.2	0.7	0.5	-0.0	0.1	-0.2	-0.3	2.4	0.2
Angina (self-reported)	0.2	0.3	1.6	0.4	0.1	-0.5	1.3	-0.6	-1.0	0.0	-0.6	0.3	-1.0	-0.5	0.3	-0.2	0.2	-0.5	-0.5	0.1	-0.1	0.2
Migraine (self-reported)	0.6	0.7	1.6	-1.1	-0.1	0.7	-0.3	-0.8	-0.3	-0.8	-0.5	-1.2	-0.1	-0.6	-1.3	-0.9	-1.3	-0.8	-0.6	-1.0	-0.8	-1.2
Medication: Ibuprofen	1.2	1.5	3.7	-1.4	-1.3	1.8	0.2	-1.0	-0.6	-0.3	-0.9	-1.5	-0.7	-0.8	-1.5	-0.7	-1.5	-1.0	-0.9	-1.8	-1.9	-1.4
Medication: Allopurinol	1.2	1.6	4.8	0.0	-0.4	1.2	2.2	-1.4	-1.7	-0.5	-1.8	-0.6	-2.1	-1.7	-0.6	-1.0	-1.0	-1.4	-1.7	-1.0	-0.2	-0.8
Medication: Omeprazole	0.4	0.5	1.3	0.0	-0.8	-0.8	1.0	-1.0	-0.6	-0.3	-0.9	0.2	-1.0	-0.8	0.4	-1.2	0.3	-0.8	-0.6	0.9	-0.2	0.1
Medication: Seretide 50 evohaler	0.7	0.8	4.5	0.6	-0.3	-0.1	2.1	-0.9	-1.7	0.1	-0.7	0.5	-1.0	-0.8	0.8	0.2	-0.2	-0.9	-0.8	-0.9	1.4	0.3
Mean time to correctly identify matches	0.4	0.7	4.1	0.4	-0.0	0.2	1.6	-0.4	-1.0	0.5	-0.9	0.5	-2.0	-0.6	0.4	0.2	0.8	-0.3	-0.6	0.1	-1.5	0.6
Heart disease (mother)	0.1	0.1	1.3	0.1	1.1	0.2	-0.3	-0.2	0.0	0.3	0.2	-0.1	0.5	0.2	0.5	-0.0	-0.3	-0.1	0.2	-0.3	0.7	-0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.9	1.1	6.3	0.5	0.3	-1.0	2.0	0.7	-2.1	-0.3	0.4	0.9	-0.6	-0.0	0.3	2.5	0.9	0.1	-0.4	-0.8	0.3	1.1
Whole body fat mass	0.1	0.5	2.9	-1.0	-1.7	-0.5	-1.1	0.0	0.2	-1.0	-0.0	-0.8	0.0	-0.0	-0.9	-0.5	-0.1	-0.1	-0.0	0.1	-0.9	-0.7
Leg fat mass (right)	0.1	0.4	2.0	-0.4	-1.4	-0.9	-1.3	0.6	0.5	-0.7	0.6	-0.2	0.5	0.5	-0.3	0.1	0.4	0.5	0.5	0.5	-0.2	-0.1
Arm predicted mass (right)	0.7	3.6	8.7	-0.4	-0.4	-1.5	-3.0	2.3	2.6	1.8	2.6	0.8	2.8	2.6	0.8	1.8	1.3	2.4	2.5	1.0	0.0	1.1
Pulse rate, automated reading	0.3	1.0	3.9	1.4	0.1	-0.4	1.9	0.2	-0.9	1.2	0.1	1.1	-0.4	-0.0	1.4	2.0	0.6	0.1	-0.1	-0.6	1.1	1.1
Alcohol intake frequency.	1.9	4.4	10.4	-1.0	-1.6	1.0	1.8	-2.7	-1.8	-1.6	-2.8	-1.8	-2.7	-2.6	-1.9	-3.2	-1.8	-2.5	-2.4	-0.8	-1.9	-1.9
Comparative height size at age 10	0.3	1.6	5.7	-2.0	-1.1	2.1	-2.4	0.1	2.0	1.2	0.3	-1.5	1.2	0.4	-0.6	-0.4	-1.0	0.3	0.5	-0.6	-1.1	-1.4
Number of full sisters	0.3	0.4	1.5	0.1	0.1	0.4	0.2	-0.9	-0.5	-1.2	-0.8	-0.4	-0.7	-0.8	-0.6	-1.1	-0.3	-0.8	-0.7	0.1	-0.5	-0.4
Suffer from ‘nerves’	0.3	0.4	2.7	0.5	0.1	-0.1	1.6	-0.3	-1.1	0.3	-0.4	0.6	-0.8	-0.5	0.6	0.7	0.3	-0.4	-0.5	-0.4	0.4	0.6
Overall health rating	0.8	1.6	5.4	-0.4	-0.4	0.4	2.2	-1.5	-2.3	-1.8	-1.5	0.0	-2.0	-1.5	-0.4	-1.3	-0.4	-1.5	-1.4	-0.6	-0.0	-0.1
Chest pain or discomfort	0.4	0.6	2.8	0.8	0.6	-0.8	1.7	-0.3	-1.3	-0.2	-0.4	0.8	-0.9	-0.4	0.9	0.4	0.6	-0.3	-0.4	0.1	1.0	0.7
Had major operations	0.8	1.0	2.2	0.2	0.7	-0.8	-0.9	1.5	0.9	1.1	1.3	0.7	0.8	1.3	0.4	1.3	1.0	1.4	1.2	0.5	-0.5	0.9
Age at last live birth	0.6	0.8	2.6	-1.2	-0.8	1.6	-0.7	-0.7	0.8	0.4	-0.7	-1.2	-0.3	-0.5	-0.7	-1.4	-1.0	-0.4	-0.4	-0.5	-1.1	-1.3
Family relationship satisfaction	6.8	8.3	14.8	-1.1	-0.4	0.6	3.1	-3.6	-3.8	-3.6	-3.7	-2.3	-3.7	-3.8	-2.5	-2.8	-2.3	-3.8	-3.8	-1.8	-1.5	-2.4
Leg pain on walking	0.2	0.3	3.3	0.4	1.8	-0.3	-0.0	-0.3	-0.3	-0.3	-0.3	-0.0	-0.5	-0.1	-0.1	-0.7	0.2	-0.2	-0.1	0.2	-0.5	0.0
Qualifications: NVQ or HND or HNC or equivalent	0.1	0.2	1.2	-0.1	0.9	-0.6	-0.3	0.2	-0.2	-1.1	0.3	-0.2	0.4	0.1	-0.6	0.1	0.1	0.0	0.0	0.2	-0.3	-0.1
Commuting to job workplace: Car/motor vehicle	2.6	2.9	6.0	1.1	2.4	-1.0	-2.2	1.8	2.0	1.4	2.2	1.1	2.4	2.2	1.5	1.6	1.2	1.9	2.2	0.9	1.1	1.2
Illness, injury, bereavement, stress in last 2 years	0.3	0.3	2.0	-0.5	-0.6	0.4	0.3	-0.3	-0.8	-0.8	-0.2	-0.5	-0.2	-0.3	-0.3	0.3	-0.7	-0.5	-0.4	-1.4	0.4	-0.5
Medication: Aspirin	0.8	1.1	2.7	-0.2	-0.7	0.4	0.8	-0.9	-1.3	-1.7	-1.1	-1.0	-1.2	-1.2	-1.4	-1.0	-0.9	-1.1	-1.2	-0.9	-0.7	-1.0
Supplements: Vitamin C	0.8	0.9	3.6	0.1	-1.9	-0.4	0.7	-1.1	-0.9	-1.2	-1.2	-0.6	-1.1	-1.3	-0.5	-1.1	-0.3	-1.2	-1.2	0.3	-0.2	-0.7
Knee pain experienced in last month	0.3	0.4	3.1	-0.5	0.3	0.2	0.2	-0.6	-0.4	-0.4	-0.6	-0.3	-1.0	-0.4	-0.5	-0.9	0.2	-0.5	-0.4	0.3	-1.8	-0.2
Hypertension (Self-reported)	0.9	2.5	8.1	1.1	-0.4	0.3	2.8	-1.3	-2.8	-2.1	-1.7	-0.1	-2.3	-2.0	-0.5	-0.6	-0.6	-1.6	-2.0	-1.0	1.4	-0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.9	2.1	0.2	-1.0	0.1	0.9	-1.0	-1.0	-1.1	-1.2	-0.5	-1.4	-1.1	-0.9	-1.2	-0.3	-1.0	-1.1	0.1	-1.0	-0.5
Illnesses of father: Heart disease	0.7	1.0	2.2	1.1	-0.5	-0.3	-0.8	1.3	1.2	0.7	1.0	1.0	0.8	1.0	1.1	1.0	1.0	1.2	1.1	0.9	1.5	0.8
Illnesses of siblings: Diabetes	0.1	0.1	0.9	-0.4	-1.0	0.0	0.2	-0.2	-0.5	-0.3	-0.3	-0.2	-0.4	-0.4	0.1	0.4	-0.0	-0.3	-0.4	-0.4	0.1	-0.2
Smoking status: Previous	0.2	0.3	2.3	-1.5	-0.4	1.1	0.3	0.0	-0.4	0.0	-0.1	-0.5	-0.3	-0.2	-0.5	-0.1	-0.7	-0.0	-0.2	-1.0	0.3	-0.5
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.7	2.2	-0.8	-0.9	0.3	-1.3	0.9	1.1	0.5	1.1	0.0	1.5	1.0	-0.1	0.7	0.1	0.8	1.0	0.2	-0.5	0.3
Whole body fat-free mass	0.5	3.1	10.2	-1.0	-0.9	-1.0	-3.2	2.2	2.6	1.2	2.4	0.4	2.8	2.4	0.3	1.3	0.9	2.2	2.3	0.9	-0.1	0.7
Leg fat-free mass (right)	0.4	2.1	8.6	-1.3	-1.3	-0.5	-2.9	1.6	2.3	0.8	1.9	-0.2	2.4	1.9	-0.2	0.7	0.2	1.6	1.8	0.4	-0.2	0.0
Arm fat percentage (left)	0.3	1.2	5.4	-1.1	-2.3	0.2	-0.5	-0.7	-0.4	-1.6	-0.9	-1.4	-0.9	-0.9	-1.3	-1.2	-0.7	-0.7	-0.8	-0.3	-0.9	-1.3
Average weekly red wine intake	0.4	0.6	1.8	-0.2	0.2	-0.7	-1.0	1.3	0.6	-0.1	1.1	0.2	1.1	0.9	-0.5	1.2	0.5	1.0	0.7	0.4	-0.5	0.4
Handedness (chirality/laterality): Left-handed	1.3	1.6	7.7	1.5	0.4	0.3	2.8	-1.0	-2.2	-0.5	-1.3	0.6	-2.2	-1.3	0.8	0.2	0.2	-1.0	-1.3	-0.5	1.1	0.3
Mood swings	2.3	4.2	6.7	-1.8	-1.6	2.2	1.2	-2.6	-1.8	-0.7	-2.2	-2.2	-1.9	-2.1	-1.8	-1.7	-2.4	-2.4	-2.1	-2.5	-2.3	-2.2
Loneliness, isolation	1.5	2.0	4.6	-0.2	-0.0	1.4	1.8	-1.8	-2.1	-1.1	-1.6	-1.1	-1.5	-1.7	-1.0	-0.8	-1.4	-1.9	-1.8	-1.6	-0.9	-1.1
Long-standing illness, disability or infirmity	0.7	1.0	3.1	-0.6	-0.2	0.3	0.7	-0.9	-1.1	-1.8	-1.1	-0.9	-1.3	-1.2	-1.4	-1.3	-0.7	-1.0	-1.2	-0.4	-0.8	-0.8
Ever had bowel cancer screening	3.0	3.5	10.4	0.1	0.4	1.0	3.2	-2.1	-3.0	-1.4	-2.3	-0.7	-3.0	-2.2	-1.3	-1.0	-0.8	-2.2	-2.4	-1.2	-2.2	-0.6
Diabetes diagnosed by doctor	1.2	1.9	6.6	2.4	1.2	-0.7	2.1	0.9	-1.2	0.3	0.6	2.1	-0.2	0.4	1.6	1.5	1.2	0.7	0.4	0.3	2.6	1.9
Ever had stillbirth, spontaneous miscarriage or termination	2.5	2.6	6.0	1.2	1.4	-2.4	-1.3	1.6	1.5	0.9	1.8	1.6	2.0	1.7	1.4	1.2	1.7	1.5	1.7	2.2	1.3	1.6
Friendships satisfaction	3.3	4.0	11.4	-1.7	-0.8	0.3	1.0	-2.1	-2.4	-3.4	-2.1	-1.9	-2.3	-2.2	-2.4	-1.8	-1.4	-2.3	-2.3	-1.3	-2.2	-1.8
Qualifications: nursing, teaching	0.2	0.4	2.1	0.4	0.3	-0.4	-0.5	0.7	0.7	0.5	0.6	0.3	0.6	0.5	0.8	0.9	0.2	0.6	0.5	0.0	1.5	0.1
Commuting to job workplace: Walk	0.7	0.8	4.0	0.5	-0.8	0.4	2.0	-0.5	-0.9	0.4	-1.1	0.3	-1.6	-1.1	0.7	0.1	-0.2	-0.5	-0.9	-0.7	1.3	-0.0
Eye problems/disorders: Cataract	0.6	0.7	2.0	-0.6	0.1	-0.4	0.4	-0.7	-1.1	-1.4	-0.7	-0.9	-0.7	-0.9	-1.2	-0.3	-0.6	-1.0	-1.0	-0.6	-1.0	-0.8
Mouth/teeth dental problems: Mouth ulcers	1.7	2.7	16.5	1.8	0.4	-0.8	4.1	-0.9	-2.7	0.4	-1.4	1.5	-2.8	-1.3	1.4	0.8	1.1	-0.9	-1.4	-0.0	0.4	1.3
Medication for cholesterol	1.0	1.5	3.6	-1.6	-0.4	1.4	0.0	-0.9	-0.4	-1.1	-0.9	-1.7	-0.4	-1.1	-1.7	-1.0	-1.9	-1.1	-1.1	-1.6	-0.7	-1.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.4	2.9	5.7	-1.5	-0.8	1.0	1.5	-1.8	-2.4	-2.1	-1.7	-1.5	-1.8	-1.8	-2.1	-1.6	-1.4	-1.9	-1.9	-1.4	-1.8	-1.4
Back pain experienced in last month	1.4	2.1	6.0	-1.2	-0.5	1.8	0.8	-2.2	-0.8	-0.3	-1.9	-1.4	-1.6	-1.7	-0.5	-2.4	-1.6	-1.8	-1.5	-1.0	-0.4	-1.6
Mineral and other dietary supplements	1.1	1.5	2.9	1.3	1.1	-0.5	-0.7	1.6	1.2	1.1	1.2	1.4	0.6	1.4	1.3	1.1	1.4	1.7	1.5	0.8	0.9	1.4
Breast cancer (self-reported)	1.7	2.0	6.7	-2.3	-1.1	1.7	-2.6	1.5	1.6	0.3	1.4	-1.3	1.8	1.2	-1.6	0.8	-0.7	1.2	1.0	-0.7	-1.3	-0.9
Asthma (self-reported)	0.9	1.8	8.8	-0.2	0.0	0.8	2.6	-1.0	-3.0	-1.1	-1.0	-0.2	-1.6	-1.3	-0.5	0.4	-1.0	-1.3	-1.5	-2.2	0.8	-0.3
Osteoporosis (self-reported)	0.8	0.9	3.3	1.1	1.8	-1.1	-0.3	0.2	0.9	1.2	0.4	1.0	0.7	0.5	1.3	-0.1	0.9	0.5	0.7	1.7	1.0	0.9
Osteoarthritis (self-reported)	0.2	0.2	1.6	0.0	1.3	-1.0	-0.1	0.1	-0.4	-0.1	0.1	-0.1	-0.1	-0.0	-0.2	0.7	0.4	-0.1	-0.2	0.1	-1.0	0.1
Medication: Aspirin	0.6	0.8	2.4	-0.1	-0.4	0.1	0.8	-0.8	-1.3	-1.6	-0.9	-0.8	-1.1	-1.0	-1.1	-1.0	-0.7	-0.9	-1.0	-0.6	-0.4	-0.8
Medication: Gliclazide	0.8	0.9	5.7	2.1	1.2	0.5	1.2	0.3	-0.9	-0.2	0.2	0.9	0.0	0.0	0.6	0.6	0.1	0.2	0.0	-0.3	2.4	0.6
Illnesses of father: None of the above (group 1)	0.3	0.3	1.2	-1.0	-1.0	0.8	-0.3	-0.3	0.3	0.5	-0.2	-0.7	0.0	-0.1	-0.6	-0.4	-0.6	-0.1	-0.1	-0.6	-1.1	-0.6
Smoking status: Current	0.7	1.1	5.9	1.2	0.9	-2.0	-0.6	0.3	0.6	-1.0	0.4	1.1	0.4	0.5	0.4	-1.1	1.3	0.4	0.6	2.4	0.3	1.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.1	5.8	1.2	-0.2	-0.6	-1.2	-0.1	2.4	1.9	-0.2	0.3	0.5	0.3	1.3	-1.2	0.4	0.5	0.7	2.0	0.4	0.0
Whole body water mass	0.5	3.1	10.1	-1.0	-1.0	-1.0	-3.2	2.1	2.6	1.2	2.4	0.4	2.8	2.4	0.3	1.3	0.9	2.1	2.3	0.9	-0.0	0.7
Leg predicted mass (right)	0.4	2.2	8.8	-1.3	-1.3	-0.5	-3.0	1.7	2.3	0.8	1.9	-0.2	2.4	1.9	-0.2	0.7	0.3	1.7	1.9	0.5	-0.2	0.1
Arm fat mass (left)	0.2	0.8	4.4	-1.4	-2.1	0.0	-1.5	0.0	0.4	-1.1	-0.0	-1.1	0.1	-0.0	-1.2	-0.8	-0.4	-0.0	-0.0	-0.1	-1.0	-1.0
Number of self-reported non-cancer illnesses	0.9	1.6	6.3	1.1	0.3	-0.8	2.5	-0.9	-2.4	-1.5	-1.4	0.4	-2.2	-1.5	-0.1	-0.3	0.4	-1.2	-1.5	0.1	0.3	0.3
Average weekly champagne plus white wine intake	0.6	0.9	2.1	-0.0	0.8	-1.5	-0.8	1.4	0.4	-0.3	1.4	0.8	1.1	1.3	-0.1	1.2	0.9	1.1	1.1	0.5	-0.3	1.0
Miserableness	2.0	3.5	6.1	-2.4	-1.3	2.0	0.2	-2.0	-1.2	-0.9	-1.6	-2.5	-1.2	-1.6	-2.2	-1.6	-2.4	-1.9	-1.7	-2.3	-2.4	-2.3
Guilty feelings	0.3	0.5	2.4	0.2	-0.6	-0.9	-0.1	0.4	-0.1	-0.6	0.2	1.0	-0.4	0.3	0.7	0.3	1.5	0.4	0.3	1.4	-0.3	1.0
Wears glasses or contact lenses	0.3	0.4	1.1	0.2	-0.8	0.9	0.9	0.0	-0.8	0.2	-0.4	-0.4	-0.7	-0.6	-0.4	1.0	-0.3	-0.3	-0.7	-1.0	-0.3	-0.4
Ever taken oral contraceptive pill	0.5	0.5	5.1	0.9	-0.2	-0.4	0.5	0.5	-0.2	-0.1	0.4	0.9	0.3	0.2	0.9	0.6	0.3	0.4	0.2	0.1	2.3	0.6
Hearing aid user	0.4	0.5	1.1	-0.6	0.4	0.4	-1.1	0.8	1.0	1.1	0.7	0.2	0.6	0.9	0.4	0.6	0.6	0.9	0.9	0.4	-0.5	0.3
Mother’s age at death	1.4	1.8	5.0	-0.1	-0.5	1.2	2.0	-1.8	-0.9	0.4	-2.1	-0.6	-2.2	-1.7	-0.4	-1.8	-1.2	-1.4	-1.5	-0.9	-0.8	-0.8
Financial situation satisfaction	1.6	1.9	5.7	-0.1	0.3	0.3	2.1	-1.5	-2.2	-2.4	-1.6	-0.3	-1.9	-1.7	-0.9	-1.7	-0.7	-1.6	-1.7	-0.3	0.3	-0.5
Tinnitus: Yes, now most or all of the time	0.2	0.2	1.1	0.6	-0.5	-0.0	1.1	-0.6	-0.8	-0.0	-0.5	0.3	-0.6	-0.6	0.3	-0.1	0.0	-0.6	-0.6	-0.0	0.1	0.2
Commuting to job workplace: Public transport	1.2	1.5	2.9	-1.6	-1.1	1.0	0.8	-1.1	-0.5	-1.1	-1.6	-1.2	-1.6	-1.5	-1.2	-1.7	-1.0	-1.1	-1.4	-0.2	-0.7	-1.3
Eye problems/disorders: Glaucoma	0.4	0.5	2.2	0.6	0.9	-1.5	0.7	0.6	-0.3	0.5	0.3	0.9	-0.3	0.2	0.8	1.3	0.9	0.5	0.2	0.3	0.4	0.9
Medication: Blood pressure	0.3	0.6	2.6	1.5	-0.3	0.1	1.6	-0.5	-1.2	-0.3	-0.8	0.6	-1.3	-0.8	0.5	-0.0	0.3	-0.5	-0.7	0.1	0.9	0.4
Pain type(s) experienced in last month: Hip pain	0.4	0.5	1.8	-1.0	0.1	0.8	-1.4	0.2	0.3	-0.7	0.7	-0.7	1.0	0.5	-0.8	-0.5	-0.8	0.2	0.5	-0.8	0.1	-0.6
Supplements: Fish oil (including cod liver oil)	0.5	0.6	1.4	-0.5	-0.5	-0.3	0.4	-1.0	-0.7	-1.0	-0.8	-0.7	-0.2	-0.9	-1.0	-1.2	-0.8	-1.1	-0.9	0.1	-0.5	-0.7
High cholesterol (Self-reported)	0.2	0.3	1.6	0.4	-0.3	-0.6	0.5	0.0	-0.6	-1.3	-0.3	0.3	-0.8	-0.4	-0.4	-0.3	0.5	-0.2	-0.4	0.7	-0.1	0.3
Medication: Bendroflumethiazide	0.2	0.4	1.7	0.7	-0.2	-0.3	-0.8	0.8	0.8	-0.1	0.5	0.3	0.4	0.5	0.1	-0.1	0.8	0.7	0.6	1.3	0.2	0.3
Medication: Paracetamol	0.7	1.0	3.0	-0.6	0.6	0.2	0.6	-1.3	-1.3	-1.7	-0.9	-0.9	-0.8	-1.0	-1.0	-1.3	-1.1	-1.3	-1.0	-1.0	-0.4	-0.9
Medication: Lisinopril	4.7	6.0	11.8	2.6	0.9	-1.6	-0.8	2.5	2.0	2.9	2.5	2.8	2.4	2.5	3.2	2.9	2.2	2.6	2.6	1.5	3.4	2.6
Medication: Atorvastatin	0.4	0.5	1.5	1.1	-0.2	-0.2	0.3	0.8	0.3	0.2	0.3	1.1	-0.2	0.4	0.7	0.4	1.2	0.8	0.5	1.2	0.8	1.1
Illnesses of father: High blood pressure	0.5	0.6	2.4	-0.8	0.2	0.7	-0.8	-0.3	-0.1	-1.6	-0.2	-1.2	0.2	-0.4	-1.5	-0.8	-0.8	-0.5	-0.5	-0.3	-0.8	-1.1
Alcohol drinker status: Never	2.8	3.3	7.0	-0.0	-0.4	1.0	2.1	-2.6	-2.2	-1.2	-2.4	-1.4	-2.0	-2.4	-1.4	-2.0	-1.8	-2.6	-2.3	-1.3	-1.3	-1.5
Ever smoked	0.4	0.6	2.3	-1.5	0.4	1.2	-1.0	-0.2	0.6	-0.4	-0.3	-1.1	0.1	-0.2	-1.0	-1.4	-1.1	-0.1	-0.1	-0.3	0.1	-1.2
Basal metabolic rate	0.4	2.2	8.9	-1.1	-1.3	-0.8	-3.0	1.7	2.2	0.7	1.9	0.0	2.3	1.9	-0.1	0.8	0.6	1.7	1.9	0.7	-0.3	0.3
Leg fat percentage (left)	0.2	0.6	4.0	-0.2	-2.0	-1.0	-0.0	-0.5	-0.5	-1.1	-0.7	-0.4	-0.9	-0.6	-0.5	-1.0	0.0	-0.5	-0.6	0.4	-0.5	-0.4
Arm fat-free mass (left)	0.6	3.0	9.7	-0.8	-0.8	-1.1	-3.1	2.1	2.4	1.2	2.4	0.5	2.7	2.4	0.3	1.3	1.0	2.1	2.3	1.0	-0.3	0.8
Number of operations (self-reported)	3.0	4.4	12.4	-0.7	1.3	-1.1	-3.5	3.3	2.3	0.5	3.2	0.5	3.2	2.8	-0.1	2.3	1.2	2.8	2.6	0.8	0.3	0.9
Average weekly beer plus cider intake	0.9	1.3	5.0	1.3	0.7	-1.4	-1.7	0.3	1.9	0.6	0.7	0.7	1.4	0.9	1.0	-0.7	0.9	0.6	1.1	2.2	0.6	0.6
Irritability	0.4	0.7	2.7	1.6	0.9	-0.7	0.6	0.4	0.1	1.0	0.5	1.2	0.4	0.5	1.4	0.7	0.7	0.5	0.6	0.5	1.2	1.1
Risk taking	0.9	1.3	3.2	0.3	1.0	-0.9	-1.1	1.8	1.2	0.8	1.4	0.8	1.2	1.4	0.3	1.1	1.1	1.6	1.3	1.2	0.4	0.9
Ever had prostate specific antigen (PSA) test	2.6	3.0	7.1	-0.3	-1.5	2.7	2.3	-1.7	-2.1	-0.9	-2.1	-1.1	-2.6	-2.1	-1.0	-1.4	-1.5	-1.7	-2.0	-1.8	-0.3	-1.3
Fractured/broken bones in last 5 years	1.1	1.4	2.6	-1.2	-1.0	1.3	0.2	-1.6	-0.7	-0.5	-1.4	-1.5	-1.1	-1.3	-1.0	-1.6	-1.3	-1.4	-1.2	-1.0	-1.2	-1.5
Age started oral contraceptive pill	0.3	0.3	1.7	0.2	0.3	1.3	0.2	-0.6	0.1	0.9	-0.6	-0.4	-0.5	-0.4	-0.0	-0.2	-0.2	-0.4	-0.4	-0.2	-1.2	-0.3
Diastolic blood pressure, automated reading	0.5	1.5	6.3	1.6	-0.1	-1.0	2.4	0.4	-1.4	1.0	0.1	1.4	-0.6	-0.1	1.6	2.5	0.9	0.1	-0.2	-0.6	1.5	1.3
Ever depressed for a whole week	1.4	1.7	5.5	-0.4	0.2	0.9	2.3	-1.5	-1.9	-0.5	-1.8	-0.5	-2.1	-1.7	-0.6	-1.0	-0.8	-1.5	-1.7	-0.9	-0.3	-0.6
Unable to work because of sickness or disability	0.4	0.5	1.2	0.2	0.1	-0.7	0.7	-0.7	-0.7	-1.1	-0.9	-0.0	-1.1	-0.9	-0.4	-1.1	0.2	-0.7	-0.8	0.9	-0.5	-0.1
Commuting to job workplace: Cycle	0.1	0.2	0.8	-0.1	-0.1	-0.7	-0.4	0.4	0.0	-0.9	0.3	-0.2	0.3	0.1	-0.8	0.2	0.1	0.1	0.0	0.3	-0.5	0.0
Myopia	0.6	0.9	2.1	0.0	-0.9	1.0	1.4	-1.0	-1.3	-0.5	-1.1	-0.6	-1.2	-1.2	-0.6	-0.3	-1.0	-1.1	-1.2	-1.3	-0.2	-0.7
Vascular/heart problems diagnosed by doctor	0.8	2.2	7.1	-1.1	0.6	0.3	-2.5	1.3	2.7	2.2	1.6	0.1	2.0	1.9	0.3	0.7	0.6	1.6	1.9	0.8	-1.7	0.5
Cholesterol lowering medication	0.5	0.7	2.0	0.5	0.2	-0.8	-0.5	0.7	0.5	0.4	0.7	1.2	0.4	0.9	1.0	0.3	1.3	0.9	0.9	1.4	0.4	1.2
Medication: Omeprazole (e.g. Zanprol)	0.9	1.0	3.4	-0.3	-1.1	-0.3	1.1	-1.4	-0.7	-0.6	-1.6	-0.3	-1.6	-1.4	-0.1	-1.8	-0.1	-1.2	-1.2	0.9	-0.5	-0.4
Pain experienced in last month	0.2	0.3	1.1	-0.2	-0.8	-0.6	-0.6	0.7	0.3	-0.0	0.7	0.3	0.9	0.5	0.3	1.1	0.3	0.5	0.4	0.1	0.7	0.3
Supplements: Calcium	0.2	0.2	0.9	-0.2	-1.0	0.4	0.0	-0.8	-0.1	0.3	-0.4	-0.3	-0.0	-0.4	0.3	-0.8	-0.5	-0.6	-0.3	-0.1	0.6	-0.5
Basal cell carcinoma (self-reported)	2.1	2.5	6.2	0.3	2.4	-1.6	-2.3	1.3	1.7	1.2	2.2	0.8	2.5	2.3	0.7	1.0	0.8	1.6	2.2	0.4	-0.6	1.1
Heart attack/myocardial infarction (self-reported)	0.5	0.6	2.5	-1.6	-0.5	-0.3	-1.1	-0.5	0.1	-0.9	-0.1	-1.1	0.3	-0.1	-1.0	-1.0	-0.6	-0.4	-0.1	-0.3	-1.2	-0.9
Deep venous thrombosis (DVT) (self-reported)	0.2	0.3	1.9	0.8	-1.4	-0.8	0.5	-0.0	-0.1	-0.0	0.0	0.6	0.1	-0.0	0.6	0.1	0.4	-0.0	0.0	0.6	0.8	0.5
Heart disease (siblings)	1.0	1.2	3.7	0.9	1.9	-1.5	-1.0	0.9	0.6	0.3	1.2	1.0	1.2	1.2	1.0	0.8	1.2	0.9	1.2	1.1	0.5	1.1
Alcohol drinker status: Previous	0.6	0.7	2.5	-0.3	-0.5	-1.6	-1.0	0.8	1.0	0.3	0.8	0.7	0.4	1.0	0.3	-0.1	1.0	1.0	1.0	1.2	-0.6	0.8
Pack years of smoking	2.4	3.5	7.7	0.8	1.0	-2.0	-2.8	2.5	2.3	0.8	2.5	1.1	2.6	2.3	0.7	1.8	1.5	2.3	2.2	1.6	0.8	1.3
Impedance of whole body	0.3	1.3	3.3	0.2	0.3	1.4	1.8	-1.6	-1.3	-0.3	-1.6	-0.7	-1.4	-1.6	-0.2	-0.6	-1.1	-1.6	-1.6	-1.0	0.1	-0.9
Leg fat mass (left)	0.1	0.5	2.1	-0.6	-1.5	-1.0	-1.5	0.5	0.6	-0.7	0.6	-0.3	0.6	0.5	-0.4	-0.1	0.3	0.5	0.5	0.5	-0.4	-0.2
Arm predicted mass (left)	0.6	2.9	9.2	-0.8	-0.7	-1.2	-3.0	2.0	2.3	1.0	2.4	0.5	2.6	2.4	0.3	1.2	1.0	2.1	2.3	0.9	-0.3	0.8