TWAS hub - EFCAB1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.6210	0.0420	0.0e+00	0.530	0.494	0.561	0.541	0.566	5.7e-76	7.5e-69	1.1e-82	2.0e-78	1.0e-83
2	ROSMAP	Brain Pre-frontal Cortex	0.6746	0.0425	0.0e+00	0.530	0.509	0.550	0.520	0.554	1.6e-80	7.8e-76	7.3e-85	2.6e-78	5.8e-86
3	TCGA	Bladder Urothelial Carcinoma	0.0750	0.0330	3.1e-05	0.088	0.049	0.061	NA	0.076	7.0e-08	5.7e-05	7.4e-06	NA	5.1e-07
4	TCGA	Breast Invasive Carcinoma	0.0278	0.0148	2.0e-04	0.034	0.017	0.025	NA	0.030	1.1e-07	1.6e-04	5.4e-06	NA	6.5e-07
5	TCGA	Colon Adenocarcinoma	0.0540	0.0320	8.7e-03	0.079	0.051	0.075	NA	0.074	2.4e-05	6.8e-04	3.9e-05	NA	4.6e-05
6	TCGA	Head and Neck Squamous Cell Carcinoma	0.0442	0.0244	3.3e-04	0.031	0.019	0.022	NA	0.015	1.9e-04	3.1e-03	1.3e-03	NA	7.0e-03
7	TCGA	Kidney Renal Clear Cell Carcinoma	0.0766	0.0299	4.8e-09	0.126	0.088	0.121	NA	0.123	4.9e-14	4.4e-10	1.8e-13	NA	1.1e-13
8	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0770	0.0370	2.0e-04	0.042	0.078	0.070	NA	0.068	1.9e-03	3.1e-05	7.4e-05	NA	9.8e-05
9	TCGA	Brain Lower Grade Glioma	0.0656	0.0256	5.2e-08	0.090	0.061	0.084	NA	0.081	2.1e-10	1.7e-07	8.2e-10	NA	1.5e-09
10	TCGA	Lung Squamous Cell Carcinoma	0.0805	0.0381	8.2e-04	0.005	0.033	0.040	NA	0.005	8.1e-02	9.7e-05	2.3e-05	NA	7.8e-02
11	TCGA	Pancreatic Adenocarcinoma	0.1570	0.0660	7.6e-06	0.174	0.122	0.149	NA	0.161	8.9e-08	8.8e-06	8.3e-07	NA	2.9e-07
12	TCGA	Prostate Adenocarcinoma	0.1355	0.0604	2.1e-10	0.131	0.029	0.083	NA	0.116	1.4e-13	5.0e-04	5.4e-09	NA	3.5e-12
13	TCGA	Thyroid Carcinoma	0.0720	0.0330	5.2e-06	0.081	0.061	0.059	NA	0.074	2.8e-08	1.5e-06	1.9e-06	NA	1.0e-07

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13
Serious illness, injury or assault to yourself	7.7	9.3	10.3	3.0	3.1	3.1	3.1	3.1	2.6	3.1	2.8	3.0	3.2	3.1	3.1	3.1
Leg pain on walking	5.3	6.6	8.2	-2.5	-2.7	-2.7	-2.7	-2.7	-2.5	-2.7	-2.5	-2.9	-0.1	-2.7	-2.6	-2.7
Knee pain experienced in last month	5.2	8.0	9.7	-3.1	-3.1	-3.0	-3.0	-3.0	-2.5	-3.0	-2.6	-2.9	-1.1	-2.9	-2.9	-3.0
Eye problems/disorders: None of the above	4.1	4.7	8.0	-1.8	-2.0	-2.3	-2.3	-2.3	-1.7	-2.3	-2.8	-2.2	-1.5	-2.3	-2.3	-2.2
Falls in the last year	4.0	5.4	6.9	-2.5	-2.4	-2.4	-2.4	-2.4	-2.2	-2.4	-2.2	-2.4	-0.8	-2.5	-2.5	-2.6
Medication: Aspirin	3.9	5.1	6.2	2.1	2.3	2.3	2.3	2.3	1.7	2.3	2.5	2.3	2.5	2.3	2.3	2.3
HbA1C	3.8	4.2	5.1	2.0	1.9	2.3	2.3	2.1	1.6	2.3	2.2	1.9	1.6	2.0	2.2	2.2
Bipolar Disorder (2011)	3.2	3.1	3.8	-1.7	-1.8	-1.9	-1.9	-1.9	-1.6	-1.9	-1.6	-1.7	-1.1	-1.7	-1.9	-1.9
Diabetes (mother)	3.1	4.0	4.8	2.2	2.0	2.1	2.1	2.2	1.8	2.1	1.7	2.1	0.8	2.1	2.1	2.1
Medication: Omeprazole	3.1	3.7	6.1	2.1	2.1	1.9	1.9	1.9	1.4	1.9	2.5	1.8	1.5	1.9	1.9	1.9
Risk taking	3.1	4.6	5.8	2.0	2.2	2.1	2.1	2.1	1.9	2.1	2.4	2.3	1.9	2.3	2.1	2.1
Cholesterol lowering medication	3.1	4.6	10.0	1.7	1.9	2.1	2.1	2.2	2.0	2.1	2.0	2.2	3.2	2.1	2.1	2.0
Hand grip strength (right)	3.0	8.1	11.4	2.9	2.7	3.0	3.0	3.2	2.5	3.0	2.3	3.4	1.8	3.0	2.9	2.9
Wheeze or whistling in the chest in last year	2.9	5.1	6.0	-2.2	-2.4	-2.4	-2.4	-2.4	-1.9	-2.4	-2.0	-2.3	-2.1	-2.3	-2.3	-2.3
Medication: Aspirin	2.9	3.8	4.6	1.7	2.0	1.9	1.9	2.0	1.5	1.9	2.1	2.0	2.2	2.0	2.0	1.9
Standing height	2.8	27.9	34.0	5.6	5.4	5.5	5.5	5.5	5.3	5.4	5.8	5.7	2.1	5.5	5.4	4.9
High cholesterol (Self-reported)	2.7	4.8	13.6	1.9	2.1	2.3	2.2	2.3	1.2	2.2	1.7	2.1	3.7	2.0	2.0	2.1
Sitting height	2.6	18.1	22.2	4.5	4.2	4.3	4.3	4.5	4.7	4.3	4.2	4.7	2.2	4.4	4.3	3.9
Height	2.5	48.3	58.8	7.5	7.3	7.2	7.2	7.2	7.4	7.1	7.7	7.4	1.2	7.2	7.1	6.5
Medication: Ibuprofen (e.g. Nurofen)	2.5	3.1	6.6	-1.6	-1.6	-1.7	-1.7	-1.9	-1.3	-1.7	-1.6	-1.9	-2.6	-1.7	-1.7	-1.6
Hearing difficulty/problems: Yes	2.4	3.7	5.1	-2.2	-2.2	-1.9	-1.9	-2.1	-1.3	-1.9	-1.9	-2.1	-0.8	-2.0	-2.0	-2.0
Illnesses of siblings	2.4	3.4	4.6	-1.7	-1.9	-1.7	-1.7	-2.0	-1.8	-1.7	-1.7	-2.1	-1.5	-2.1	-1.8	-1.9
Heart disease (siblings)	2.4	3.0	3.7	1.7	1.8	1.7	1.7	1.9	1.7	1.7	1.9	1.8	1.1	1.8	1.8	1.7
Schizophrenia vs Biploar Disorder	2.3	3.0	3.8	1.6	2.0	1.8	1.8	1.9	1.4	1.8	1.6	1.9	1.8	1.8	1.7	1.7
Tinnitus: Yes, but not now, but have in the past	2.3	2.4	5.9	1.5	1.6	1.5	1.5	1.7	0.8	1.5	1.3	1.6	2.4	1.5	1.5	1.4
Taking other prescription medications	2.2	3.4	4.0	2.0	2.0	1.8	1.8	1.8	1.7	1.8	1.5	1.8	1.7	1.9	1.9	1.9
Alcohol intake frequency.	2.2	5.1	7.4	2.3	2.2	2.1	2.1	2.1	2.3	2.2	2.3	2.1	2.7	2.3	2.3	2.1
Diabetes diagnosed by doctor	2.2	3.6	5.3	1.6	1.8	1.9	1.9	2.1	2.0	1.9	2.3	2.0	1.4	2.0	1.9	1.9
Illnesses of father: None of the above (group 1)	2.2	2.7	4.7	-2.2	-1.9	-1.7	-1.7	-1.7	-1.3	-1.7	-1.2	-1.7	-0.9	-1.6	-1.6	-1.7
Hair/balding pattern: Pattern 3	2.1	3.2	4.5	-1.8	-2.1	-1.9	-1.9	-1.9	-2.1	-1.9	-0.8	-1.8	-0.7	-1.8	-1.9	-1.9
Medication: Omeprazole (e.g. Zanprol)	2.1	2.6	3.6	1.7	1.7	1.7	1.7	1.6	0.9	1.7	1.9	1.5	1.3	1.6	1.7	1.7
Trunk predicted mass	2.0	11.2	18.3	3.3	3.3	3.3	3.3	3.4	3.9	3.3	4.3	3.6	-0.5	3.5	3.3	2.9
Hair/balding pattern: Pattern 4	2.0	4.8	7.8	-2.4	-2.2	-2.3	-2.3	-2.2	-1.2	-2.3	-2.8	-2.1	-2.0	-2.1	-2.2	-2.1
Nervous feelings	1.9	3.6	4.6	1.9	1.8	2.2	2.2	2.1	1.2	2.2	1.7	1.9	1.5	1.9	2.0	2.0
Trunk fat-free mass	1.9	10.7	17.2	3.2	3.2	3.3	3.3	3.3	3.9	3.3	4.2	3.5	-0.6	3.4	3.3	2.9
Glaucoma (self-reported)	1.9	2.3	3.1	1.3	1.3	1.7	1.7	1.6	1.5	1.7	1.1	1.6	0.7	1.6	1.7	1.8
Medication: Amlodipine	1.9	2.7	4.4	-1.9	-1.7	-1.5	-1.5	-1.6	-2.1	-1.5	-1.5	-1.7	1.0	-1.7	-1.6	-1.6
Medication: Metformin	1.8	2.6	3.5	1.5	1.7	1.5	1.5	1.8	1.8	1.5	1.7	1.9	1.1	1.7	1.6	1.6
Diabetes (self-reported)	1.8	2.8	4.8	1.4	1.4	1.6	1.6	1.7	1.8	1.6	2.2	1.7	1.7	1.7	1.6	1.6
Peak expiratory flow (PEF)	1.8	4.1	5.7	2.4	2.3	2.2	2.2	2.1	1.8	2.2	1.4	2.2	0.9	2.0	2.1	2.1
Arm fat-free mass (left)	1.8	9.2	15.8	3.0	3.0	3.0	3.0	3.1	3.6	3.0	4.0	3.3	0.4	3.2	3.0	2.7
Multivitamins +/- minerals	1.7	2.2	4.9	1.3	1.3	1.4	1.4	1.3	1.4	1.4	1.8	1.3	2.2	1.4	1.3	1.4
Medication: Ibuprofen	1.7	2.1	6.3	-1.2	-1.1	-1.3	-1.3	-1.4	-1.2	-1.3	-1.5	-1.6	-2.5	-1.4	-1.2	-1.1
Average weekly red wine intake	1.7	2.5	5.6	-1.3	-1.3	-1.5	-1.5	-1.6	-1.1	-1.5	-1.5	-1.6	-2.4	-1.7	-1.6	-1.6
Smoking Status	1.6	3.7	5.0	-2.2	-2.1	-1.9	-1.9	-2.0	-2.0	-1.9	-1.6	-1.9	-1.7	-2.0	-1.9	-1.9
Hand grip strength (left)	1.6	4.2	6.4	1.9	1.7	2.3	2.3	2.5	1.7	2.3	1.6	2.5	0.6	2.1	2.1	2.3
Medication for hormone replacement therapy	1.6	1.8	2.5	-1.4	-1.5	-1.2	-1.2	-1.4	-1.4	-1.2	-1.3	-1.6	-1.2	-1.4	-1.2	-1.0
Diverticular disease/diverticulitis (self-reported)	1.6	1.9	2.7	1.3	1.3	1.5	1.5	1.5	0.8	1.5	0.7	1.3	1.6	1.3	1.5	1.4
Medication: Paracetamol	1.6	2.6	3.9	-2.0	-1.7	-1.6	-1.6	-1.7	-1.8	-1.6	-1.4	-1.7	-0.4	-1.7	-1.6	-1.5
Whole body fat-free mass	1.6	9.4	15.0	3.0	3.0	3.0	3.0	3.1	3.8	3.0	3.9	3.3	-0.4	3.2	3.1	2.7
Whole body water mass	1.6	9.0	14.9	3.0	2.9	2.9	2.9	3.0	3.7	2.9	3.9	3.2	-0.4	3.1	3.0	2.6
Cardiovascular Disease	1.5	4.8	16.0	1.7	1.8	2.0	2.0	2.2	1.8	2.0	1.9	2.3	4.0	2.1	2.0	2.0
Other serious medical condition/disability diagnosed by doctor	1.5	1.9	2.4	1.4	1.3	1.4	1.4	1.4	1.4	1.4	1.5	1.5	1.0	1.5	1.4	1.3
Vitamin and mineral supplements	1.5	2.0	4.2	-1.4	-1.4	-1.4	-1.4	-1.3	-1.0	-1.4	-1.6	-1.1	-2.1	-1.3	-1.3	-1.4
Current tobacco smoking	1.5	2.5	3.3	-1.6	-1.5	-1.6	-1.6	-1.6	-1.8	-1.6	-1.6	-1.6	-1.3	-1.6	-1.6	-1.5
Medication: Blood pressure	1.5	2.6	9.3	1.3	1.3	1.6	1.6	1.8	0.9	1.5	0.9	1.8	3.1	1.5	1.4	1.3
Arm predicted mass (right)	1.5	7.6	12.8	2.8	2.7	2.6	2.6	2.8	3.4	2.7	3.6	3.0	0.3	2.9	2.7	2.3
Qualifications: NVQ or HND or HNC or equivalent	1.5	1.9	3.1	-1.8	-1.6	-1.3	-1.3	-1.5	-0.9	-1.3	-1.5	-1.3	-1.4	-1.2	-1.3	-1.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.5	1.7	11.1	1.0	0.8	1.1	1.1	0.9	0.5	1.0	1.3	0.8	3.3	1.0	1.0	1.0
Number of self-reported non-cancer illnesses	1.5	2.6	9.5	1.2	1.2	1.5	1.5	1.7	1.3	1.5	0.9	1.6	3.1	1.5	1.5	1.3
Commuting to job workplace: Public transport	1.5	1.8	2.7	1.5	1.5	1.4	1.4	1.3	1.3	1.4	1.6	1.0	0.6	1.3	1.4	1.4
Heel T-Score	1.4	11.4	15.9	-3.7	-3.4	-3.5	-3.5	-3.5	-3.2	-3.5	-4.0	-3.4	-1.4	-3.4	-3.5	-3.1
Lung FVC	1.4	7.2	11.1	-2.7	-2.7	-2.8	-2.8	-2.7	-2.7	-2.8	-3.3	-2.7	-1.3	-2.7	-2.7	-2.6
Qualifications: CSEs or equivalent	1.4	1.8	2.7	-1.5	-1.6	-1.4	-1.4	-1.4	-0.5	-1.3	-1.6	-1.4	-1.5	-1.3	-1.2	-1.1
Depression (self-reported)	1.4	1.6	6.1	1.1	1.2	1.3	1.3	1.3	0.4	1.3	0.8	1.1	2.5	1.1	1.2	1.1
Forced expiratory volume in 1-second (FEV1), predicted	1.4	3.0	3.9	2.0	1.8	1.8	1.8	1.8	2.0	1.8	1.7	1.9	-0.1	1.8	1.8	1.6
Smoking status: Current	1.4	2.1	3.3	-1.4	-1.3	-1.4	-1.4	-1.4	-1.8	-1.4	-1.6	-1.5	-1.3	-1.5	-1.5	-1.4
Ever taken oral contraceptive pill	1.4	1.6	2.6	1.6	1.6	1.4	1.4	1.3	0.8	1.4	0.8	1.1	-0.6	1.2	1.3	1.4
Tinnitus: Yes, now most or all of the time	1.4	1.6	3.9	1.2	1.0	1.3	1.3	1.1	2.0	1.3	1.0	1.1	1.1	1.2	1.3	1.3
Basal metabolic rate	1.4	7.5	12.5	2.7	2.7	2.7	2.7	2.8	3.3	2.7	3.5	3.0	-0.2	2.9	2.7	2.4
Arm predicted mass (left)	1.4	7.3	12.1	2.7	2.6	2.6	2.6	2.8	3.2	2.7	3.5	2.9	0.0	2.8	2.7	2.4
Triglycerides	1.3	2.1	4.3	1.3	1.1	1.3	1.4	1.4	2.1	1.4	1.4	1.6	0.7	1.6	1.5	1.5
Arm fat-free mass (right)	1.3	6.8	12.1	2.6	2.6	2.5	2.5	2.6	3.2	2.5	3.5	2.9	0.1	2.7	2.5	2.2
Long-standing illness, disability or infirmity	1.3	2.0	2.3	1.4	1.4	1.5	1.5	1.4	1.5	1.5	1.2	1.5	1.2	1.5	1.5	1.4
Waist Hip Ratio (WHR)	1.2	5.5	7.5	2.3	2.3	2.4	2.4	2.3	2.3	2.4	2.7	2.5	0.4	2.6	2.5	2.4
Ever highly irritable/argumentative for 2 days	1.2	1.5	3.5	1.1	1.0	1.2	1.2	1.3	0.9	1.3	1.0	1.1	1.9	1.1	1.2	1.1
Medication: Co-codamol	1.1	1.3	2.6	0.7	0.8	1.1	1.1	1.2	1.0	1.1	1.3	1.3	1.6	1.2	1.1	1.0
Leg fat-free mass (left)	1.1	5.9	9.5	2.3	2.4	2.4	2.4	2.5	3.0	2.4	3.1	2.7	-0.1	2.6	2.4	2.1
Heel bone mineral density (BMD) T-score, automated (left)	1.1	2.5	4.2	-1.5	-1.4	-1.5	-1.5	-1.5	-1.4	-1.5	-2.0	-1.4	-2.0	-1.5	-1.5	-1.4
Had menopause	1.1	1.4	2.9	-1.7	-1.5	-1.2	-1.2	-1.2	-1.1	-1.1	-1.2	-1.2	-0.2	-1.1	-1.1	-1.2
Pain all over the body in last month	1.1	1.2	4.6	-0.8	-1.0	-1.1	-1.1	-1.1	-0.5	-1.1	-0.8	-1.0	-2.2	-1.0	-1.0	-1.0
Comparative height size at age 10	1.1	6.1	10.9	2.6	2.6	2.4	2.4	2.5	2.7	2.4	3.3	2.6	0.5	2.6	2.5	2.1
Illnesses of father: Heart disease	1.1	1.5	2.5	1.6	1.4	1.2	1.2	1.2	1.3	1.2	1.2	1.2	-0.3	1.2	1.2	1.2
Illnesses of siblings: Diabetes	1.1	1.4	2.8	1.2	1.1	1.1	1.1	1.2	1.0	1.1	1.7	1.4	0.3	1.4	1.2	1.2
Handedness (chirality/laterality): Left-handed	1.1	1.3	3.2	-0.8	-0.8	-1.0	-1.0	-1.1	-1.4	-1.1	-0.7	-1.2	-1.8	-1.2	-1.1	-1.1
Mood swings	1.1	2.0	3.0	-1.6	-1.5	-1.2	-1.2	-1.3	-1.7	-1.2	-1.6	-1.6	-0.8	-1.5	-1.3	-1.3
Eye problems/disorders: Cataract	1.1	1.3	1.9	1.2	1.1	1.3	1.3	1.4	0.8	1.3	1.1	1.2	0.4	1.2	1.2	1.1
Eye problems/disorders: Glaucoma	1.1	1.3	1.8	0.9	1.0	1.3	1.3	1.3	1.1	1.3	0.8	1.3	-0.2	1.3	1.4	1.3
Average weekly beer plus cider intake	1.1	1.5	2.7	-1.4	-1.3	-1.2	-1.2	-1.2	-1.7	-1.2	-1.3	-1.2	-0.0	-1.2	-1.2	-1.1
Supplements: Calcium	1.1	1.2	1.5	1.1	1.1	1.2	1.2	1.1	0.8	1.2	0.8	0.9	0.9	1.1	1.2	1.1
Body Mass Index (BMI) (2010)	1.0	1.3	1.7	-1.3	-1.2	-1.1	-1.1	-1.1	-1.2	-1.1	-1.3	-1.2	-0.6	-1.2	-1.1	-1.2
Number of treatments/medications taken	1.0	1.9	5.6	1.2	1.3	1.3	1.3	1.4	0.9	1.3	1.0	1.3	2.4	1.3	1.3	1.3
Relative age voice broke	1.0	1.5	2.5	-1.4	-1.6	-1.3	-1.3	-1.3	-0.2	-1.3	-1.4	-1.0	-0.7	-1.2	-1.4	-1.2
Leg predicted mass (left)	1.0	5.5	8.8	2.3	2.3	2.3	2.3	2.4	2.9	2.3	3.0	2.6	-0.2	2.5	2.3	2.0
Financial difficulties in last 2 years	1.0	1.3	1.5	-1.2	-1.1	-1.2	-1.2	-1.2	-0.9	-1.2	-1.2	-1.2	-0.5	-1.2	-1.2	-1.2
Number of live births	1.0	1.4	6.4	0.7	0.9	1.0	1.0	1.2	1.3	1.0	0.4	1.3	2.5	1.1	1.0	0.9
Serious illness, injury or assault of a close relative in last 2 years	1.0	1.1	2.4	1.1	1.2	0.9	0.9	1.0	1.6	1.0	1.1	1.1	0.3	1.1	1.0	1.0
Supplements: Vitamin C	1.0	1.1	1.7	1.3	1.3	1.1	1.1	1.1	0.4	1.1	1.0	1.0	0.8	1.0	1.1	1.1
Leg fat-free mass (right)	1.0	5.1	9.7	2.1	2.1	2.1	2.1	2.2	3.0	2.2	3.1	2.5	-0.4	2.4	2.2	1.9
Breast cancer (self-reported)	1.0	1.2	1.9	-1.3	-1.4	-1.0	-1.0	-1.1	-0.8	-1.0	-1.3	-1.3	-1.0	-1.2	-1.0	-1.0
Leg predicted mass (right)	1.0	5.3	10.1	2.2	2.1	2.2	2.2	2.3	3.0	2.2	3.2	2.5	-0.4	2.4	2.3	1.9
Pain experienced in last month	1.0	1.6	2.6	1.1	1.2	1.2	1.2	1.3	0.9	1.2	1.6	1.3	1.6	1.3	1.2	1.2
Worry (Nagel 2018)	0.9	1.8	2.5	1.4	1.4	1.6	1.6	1.5	0.5	1.6	0.9	1.1	1.6	1.1	1.4	1.3
Fasting Glucose	0.9	1.0	2.3	1.5	1.5	-1.3	-1.2	0.8	0.4	-0.9	1.1	-0.2	0.1	1.3	1.2	-0.0
Relative age of first facial hair	0.9	1.9	3.3	-1.6	-1.5	-1.4	-1.4	-1.3	-0.7	-1.4	-1.8	-1.1	-1.2	-1.4	-1.5	-1.4
Severe depression (siblings)	0.9	1.0	1.6	-1.1	-1.0	-0.9	-0.9	-1.0	-0.8	-0.9	-1.1	-1.0	-1.3	-1.0	-0.9	-1.0
Medication: Levothyroxine sodium	0.9	1.5	3.5	1.4	1.2	1.2	1.2	1.3	1.2	1.2	0.7	1.1	1.9	1.1	1.2	1.1
High blood pressure (mother)	0.9	1.3	6.8	1.0	0.8	0.9	0.9	1.0	1.1	0.9	0.5	1.0	2.6	0.9	0.9	0.7
Hayfever/allergic rhinitis (self-reported)	0.9	1.2	3.1	-1.0	-1.0	-1.1	-1.1	-1.1	-0.7	-1.1	-0.8	-1.1	-1.8	-1.1	-1.1	-1.1
Happiness	0.9	1.1	2.3	-1.0	-1.0	-0.9	-0.9	-1.1	-1.2	-0.9	-1.5	-1.1	-1.0	-1.1	-1.0	-0.7
Qualifications: College or University degree	0.9	2.9	4.2	2.1	1.8	1.8	1.8	1.7	1.1	1.7	1.7	1.5	1.8	1.5	1.7	1.7
Neck or shoulder pain in last month	0.9	1.3	2.2	-1.4	-1.5	-1.1	-1.1	-1.1	-1.4	-1.1	-0.6	-1.2	0.9	-1.1	-1.1	-1.2
Commuting to job workplace: Car/motor vehicle	0.9	1.1	1.8	-1.4	-1.2	-1.2	-1.2	-1.0	-1.0	-1.2	-0.5	-0.7	-0.0	-0.8	-1.1	-1.2
Ever had prostate specific antigen (PSA) test	0.9	1.1	2.7	0.9	1.1	0.9	0.9	0.8	0.6	0.9	1.6	0.8	1.5	1.0	0.9	0.9
Myopia	0.9	1.2	1.7	-1.2	-1.2	-1.0	-1.0	-1.1	-1.3	-1.0	-1.1	-1.2	-0.5	-1.3	-1.1	-1.2
Type 2 Diabetes (T2D) (2012)	0.8	0.9	1.6	1.1	1.3	0.7	0.7	1.0	1.3	0.8	0.6	1.1	0.4	1.2	1.0	0.9
Qualifications: A levels/AS levels or equivalent	0.8	1.7	6.7	1.4	1.2	1.0	1.0	1.0	0.7	1.0	1.9	1.1	2.6	1.2	1.0	0.9
Prospective memory result	0.8	0.9	2.3	-0.9	-0.8	-0.9	-0.9	-0.9	-1.0	-0.9	-1.5	-0.8	-1.2	-0.9	-0.8	-0.7
Illnesses of mother	0.8	1.0	6.0	-0.9	-0.9	-0.7	-0.7	-0.9	-0.7	-0.7	-0.3	-0.8	-2.5	-0.8	-0.8	-0.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.8	2.4	3.2	1.6	1.6	1.6	1.6	1.5	1.4	1.6	1.8	1.6	1.2	1.6	1.6	1.5
Worry too long after embarrassment	0.8	1.3	1.8	1.1	1.1	1.3	1.3	1.2	0.6	1.3	1.0	0.9	1.1	1.1	1.3	1.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.8	1.0	2.1	0.9	0.9	0.9	0.9	0.9	1.5	0.9	1.2	0.9	0.5	0.9	0.9	0.9
Alcohol drinker status: Never	0.8	1.0	2.0	0.9	0.9	0.8	0.8	0.8	1.1	0.8	1.4	0.9	1.4	1.0	0.8	0.9
Number of operations (self-reported)	0.8	1.3	2.1	-1.4	-1.2	-1.0	-1.0	-1.1	-1.4	-1.0	-1.1	-1.2	-0.6	-1.2	-1.1	-1.0
Age started oral contraceptive pill	0.8	1.1	1.9	-1.1	-0.9	-1.0	-1.0	-0.9	-1.3	-1.0	-1.4	-0.9	-0.4	-1.0	-1.1	-1.1
Rheumatoid Arthritis	0.7	1.0	3.5	0.6	1.0	0.8	0.8	0.9	0.9	0.8	1.9	1.1	1.0	1.0	0.8	0.8
Schizophrenia (2014)	0.7	1.5	3.4	1.1	1.3	1.2	1.2	1.3	0.8	1.2	0.9	1.3	1.9	1.1	1.2	1.1
Systolic Blood Pressure	0.7	3.7	11.7	1.9	1.8	1.6	1.6	1.9	1.5	1.6	1.7	2.2	3.4	1.9	1.5	1.4
Hypothyroidism (self reported)	0.7	1.7	2.1	1.4	1.2	1.3	1.3	1.4	1.4	1.3	0.8	1.4	1.4	1.3	1.3	1.3
Diabetes (father)	0.7	0.9	1.7	0.8	0.9	0.9	0.9	1.0	1.3	0.9	0.4	1.1	-1.1	1.0	0.9	1.0
Forced expiratory volume in 1-second (FEV1)	0.7	2.3	2.8	1.6	1.6	1.6	1.6	1.6	1.2	1.6	1.4	1.7	0.9	1.6	1.6	1.5
Number of children fathered	0.7	0.8	0.9	-0.8	-0.8	-0.9	-0.9	-0.9	-0.9	-0.9	-0.9	-0.9	-0.7	-0.9	-0.9	-0.9
Suffer from ‘nerves’	0.7	1.2	1.8	1.2	1.3	1.3	1.3	1.2	0.2	1.3	0.7	0.9	0.9	0.9	1.2	1.1
Friendships satisfaction	0.7	0.9	2.3	0.7	0.7	0.9	0.9	0.9	0.8	0.9	1.3	0.9	1.5	0.9	0.9	0.9
Osteoarthritis (self-reported)	0.7	0.9	1.1	-1.0	-1.0	-1.0	-1.0	-1.0	-0.9	-1.0	-0.9	-1.0	-0.6	-0.9	-1.0	-1.0
Depression (Nagel 2018)	0.6	0.9	1.9	-1.1	-1.0	-0.7	-0.7	-0.9	-0.8	-0.8	-1.4	-0.9	-1.2	-1.0	-0.9	-0.7
Schizophrenia (2018)	0.6	1.2	1.9	0.8	1.0	1.2	1.1	1.2	0.7	1.1	0.8	1.4	1.4	1.0	1.0	1.0
Pack years adult smoking proportion	0.6	0.9	1.3	-1.1	-1.1	-1.0	-1.0	-1.0	-0.7	-1.0	-0.5	-0.9	0.3	-0.9	-1.0	-1.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.8	1.5	-1.0	-1.0	-0.7	-0.7	-0.8	-0.7	-0.7	-1.2	-0.9	-1.2	-0.9	-0.8	-0.7
Qualifications: None of the above	0.6	1.4	2.1	-1.5	-1.2	-1.2	-1.2	-1.1	-1.4	-1.2	-1.0	-1.0	-0.5	-1.1	-1.2	-1.4
Heart attack	0.6	0.8	1.9	1.0	1.0	0.9	0.9	0.9	0.3	0.9	0.8	0.8	1.4	0.8	0.9	0.9
Medication: Simvastatin	0.6	0.9	6.9	0.6	0.9	0.7	0.7	0.8	-0.7	0.7	0.3	0.7	2.6	0.6	0.5	0.6
Weight	0.6	2.8	5.7	1.5	1.6	1.6	1.6	1.7	1.9	1.6	2.4	1.8	0.6	1.8	1.6	1.4
Asthma	0.6	1.2	1.7	-0.9	-1.2	-1.3	-1.3	-1.2	-0.7	-1.3	-0.8	-1.1	-0.3	-1.1	-1.2	-1.3
Breastfed as a baby	0.6	0.7	1.7	-0.8	-0.9	-1.0	-1.0	-0.7	-0.6	-0.9	-1.3	-0.5	0.3	-0.8	-0.9	-1.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.6	0.9	3.4	-0.9	-0.8	-0.7	-0.7	-0.6	-1.8	-0.7	-1.2	-0.9	-0.4	-1.0	-0.8	-0.9
Medication for cholesterol, blood pressure or diabetes	0.6	1.0	5.8	-0.6	-0.7	-0.8	-0.8	-1.0	-0.1	-0.8	-0.6	-1.0	-2.4	-0.8	-0.7	-0.6
Hypothyroidism/myxoedema (self-reported)	0.6	1.1	3.9	1.1	0.9	1.0	1.0	1.1	1.1	1.0	0.5	1.0	2.0	0.9	1.0	0.9
Overall health rating	0.6	1.2	1.4	0.9	1.1	1.1	1.1	1.2	1.0	1.1	0.9	1.1	1.2	1.2	1.2	1.1
Chest pain or discomfort	0.6	0.8	2.6	0.7	0.5	0.9	0.9	0.8	1.1	0.9	0.9	0.7	1.6	0.8	0.9	0.8
Illness, injury, bereavement, stress in last 2 years	0.6	0.8	2.2	-0.5	-0.8	-0.8	-0.8	-0.9	-0.7	-0.9	-0.6	-0.8	-1.5	-0.9	-0.9	-0.9
Hearing aid user	0.6	0.6	3.2	-1.0	-0.9	-0.7	-0.7	-0.7	-0.3	-0.7	-0.5	-0.6	-1.8	-0.5	-0.6	-0.5
Irritable Bowel Disease (IBD)	0.5	1.3	2.8	-1.1	-0.8	-1.1	-1.1	-0.9	-1.6	-1.1	-1.7	-1.1	0.6	-1.1	-1.0	-1.1
Ulcerative Colitis (UC)	0.5	0.9	1.2	-1.0	-0.9	-1.1	-1.1	-0.8	-0.9	-1.1	-1.1	-0.8	0.8	-0.8	-0.9	-1.1
Breast Cancer	0.5	1.3	1.9	-1.3	-1.4	-1.0	-1.0	-1.3	-0.7	-1.0	-0.9	-1.4	-0.9	-1.3	-1.1	-1.0
Type 2 Diabetes (T2D) (2018)	0.5	0.9	2.5	0.4	0.7	0.8	0.8	1.0	1.6	0.9	1.2	1.1	0.4	1.1	1.0	1.0
Ever used hormone-replacement therapy (HRT)	0.5	0.6	1.3	-1.0	-0.9	-0.6	-0.6	-0.6	-0.8	-0.6	-1.1	-0.9	-0.6	-0.8	-0.6	-0.7
Supplements: Glucosamine	0.5	0.7	1.1	-0.9	-0.7	-0.8	-0.8	-0.8	-1.0	-0.8	-0.6	-0.9	-0.6	-0.8	-0.9	-0.9
Number of incorrect matches in round	0.5	0.9	1.5	-1.0	-0.7	-0.9	-0.9	-1.1	-0.7	-0.9	-1.0	-1.2	-0.3	-1.1	-1.0	-0.9
Hair/balding pattern: Pattern 2	0.5	0.6	2.2	0.8	0.7	0.8	0.8	0.6	1.5	0.8	0.5	0.6	0.0	0.7	0.8	0.8
Arm fat percentage (right)	0.5	1.9	2.7	-1.6	-1.3	-1.5	-1.5	-1.4	-1.7	-1.5	-1.0	-1.4	-0.0	-1.3	-1.4	-1.4
Medication: Ventolin 100micrograms inhaler	0.5	0.6	1.6	-0.2	-0.5	-0.8	-0.8	-0.7	-0.9	-0.7	-1.0	-0.8	-1.3	-0.8	-0.7	-0.7
Forced vital capacity (FVC), Best measure	0.5	1.7	2.0	1.3	1.2	1.3	1.3	1.3	1.0	1.3	1.4	1.4	1.0	1.4	1.3	1.3
Angina (self-reported)	0.5	0.6	2.8	0.4	0.7	0.8	0.8	0.8	0.4	0.8	0.6	0.8	1.7	0.6	0.6	0.4
Medication: Allopurinol	0.5	0.6	0.9	-0.7	-0.8	-0.8	-0.8	-0.7	-0.9	-0.8	-1.0	-0.6	-0.2	-0.9	-0.9	-0.8
Heart disease (mother)	0.5	0.6	2.1	0.8	0.8	0.6	0.6	0.7	0.5	0.6	0.4	0.7	1.4	0.7	0.6	0.6
Arm fat percentage (left)	0.5	2.2	2.9	-1.7	-1.4	-1.7	-1.7	-1.5	-1.7	-1.7	-1.0	-1.4	0.2	-1.4	-1.6	-1.6
Commuting to job workplace: Walk	0.5	0.5	2.1	-0.5	-0.6	-0.6	-0.6	-0.7	-0.4	-0.6	-0.8	-0.8	-1.4	-0.7	-0.7	-0.6
Medication for cholesterol	0.5	0.8	3.7	-0.4	-0.6	-0.9	-0.9	-0.9	-0.1	-0.9	-0.5	-0.6	-1.9	-0.7	-0.9	-0.9
Pain type(s) experienced in last month: Hip pain	0.5	0.6	1.5	-1.2	-1.2	-0.7	-0.7	-0.9	0.2	-0.7	-0.9	-0.9	-0.4	-0.7	-0.6	-0.6
Medication: Atorvastatin	0.5	0.6	1.0	0.7	0.6	0.7	0.7	0.9	0.8	0.7	0.6	0.8	1.0	0.8	0.7	0.7
Illnesses of father: High blood pressure	0.5	0.7	2.4	1.0	0.7	0.8	0.8	0.8	1.6	0.8	0.2	0.7	-0.3	0.7	0.8	0.9
Bipolar Disorder (2018)	0.4	0.6	1.2	-0.7	-0.8	-0.7	-0.7	-1.0	-0.6	-0.7	-0.4	-1.1	-1.0	-0.8	-0.7	-0.7
Respiratory disease	0.4	0.9	2.4	1.0	0.9	0.7	0.7	0.7	1.1	0.7	1.4	0.8	1.5	0.9	0.7	0.6
Frequency of depressed mood in last 2 weeks	0.4	0.5	1.4	-0.7	-0.6	-0.4	-0.4	-0.5	-0.8	-0.4	-1.2	-0.6	-1.2	-0.8	-0.5	-0.5
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.6	3.5	-0.8	-0.8	-0.4	-0.4	-0.5	-0.8	-0.4	-1.9	-0.8	-0.2	-0.8	-0.5	-0.4
Had other major operations	0.4	0.5	1.5	-1.0	-0.8	-0.6	-0.6	-0.7	-1.2	-0.6	-0.3	-0.9	0.1	-0.8	-0.6	-0.7
Forced vital capacity (FVC)	0.4	1.7	2.2	1.2	1.3	1.4	1.4	1.4	0.9	1.4	1.2	1.5	0.7	1.4	1.4	1.3
Impedance of arm (left)	0.4	1.9	4.1	-1.1	-1.1	-1.2	-1.2	-1.2	-2.0	-1.2	-2.0	-1.4	1.3	-1.4	-1.2	-1.1
Length of working week for main job	0.4	0.4	5.0	0.2	0.1	-0.2	-0.2	-0.1	0.7	-0.2	-0.4	0.2	-2.2	0.1	-0.1	-0.1
Exposure to tobacco smoke at home	0.4	0.5	1.6	-0.5	-0.5	-0.5	-0.5	-0.5	-0.9	-0.5	-0.7	-0.5	-1.3	-0.7	-0.5	-0.6
Body fat percentage	0.4	1.6	2.0	-1.4	-1.2	-1.4	-1.4	-1.3	-1.4	-1.4	-1.0	-1.2	0.6	-1.2	-1.3	-1.3
Pulse wave peak to peak time	0.4	0.4	2.1	0.5	0.4	0.5	0.5	0.7	0.1	0.5	0.3	0.8	1.4	0.6	0.6	0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	1.8	0.6	0.5	0.7	0.6	0.6	1.3	0.6	0.4	0.7	0.4	0.7	0.6	0.6
Pulse rate, automated reading	0.4	1.4	3.0	1.2	1.3	1.0	1.0	1.1	1.3	1.0	1.2	1.2	1.7	1.0	0.9	1.0
Ever had bowel cancer screening	0.4	0.5	0.8	0.8	0.9	0.7	0.7	0.6	0.4	0.7	0.7	0.4	0.8	0.6	0.8	0.7
Asthma (self-reported)	0.4	0.8	1.2	-0.7	-0.9	-1.0	-1.0	-1.0	-0.4	-1.0	-0.6	-0.9	-0.1	-0.9	-1.0	-1.1
Wears glasses or contact lenses	0.4	0.5	0.8	-0.7	-0.7	-0.8	-0.8	-0.7	-0.7	-0.8	-0.0	-0.6	0.9	-0.6	-0.8	-0.8
Supplements: Fish oil (including cod liver oil)	0.4	0.6	1.1	-1.1	-1.0	-0.7	-0.7	-0.8	-0.4	-0.7	-0.8	-0.7	-0.4	-0.8	-0.8	-0.8
Irritability	0.4	0.6	2.6	-0.9	-0.7	-0.6	-0.6	-0.6	-0.6	-0.5	-1.6	-0.8	-0.8	-0.7	-0.5	-0.6
Pack years of smoking	0.4	0.6	0.9	-1.0	-0.9	-0.9	-0.9	-0.8	-0.5	-0.9	-0.3	-0.7	0.3	-0.7	-0.9	-1.0
Intelligence (Savage-Jansen 2018)	0.3	0.8	1.3	1.1	1.0	0.9	0.9	1.0	0.6	0.9	1.0	0.7	0.9	0.8	0.9	0.9
Crohns Disease (2017)	0.3	0.7	2.7	-0.6	-0.3	-0.5	-0.5	-0.6	-1.6	-0.5	-1.6	-0.9	-0.2	-0.9	-0.6	-0.5
Ovarian Cancer	0.3	0.4	0.8	-0.5	-0.7	-0.7	-0.7	-0.8	0.9	-0.7	-0.4	-0.7	0.2	-0.6	-0.6	-0.8
Age at First Birth	0.3	0.4	0.7	-0.6	-0.8	-0.6	-0.6	-0.7	-0.2	-0.6	-0.8	-0.7	-0.3	-0.7	-0.6	-0.8
Coronary Artery Disease (CAD)	0.3	0.4	0.6	0.8	0.7	0.6	0.6	0.7	0.3	0.7	0.7	0.4	-0.2	0.6	0.8	0.6
Tanning	0.3	3.6	8.2	-1.9	-1.8	-1.9	-1.9	-1.8	-1.3	-1.9	-1.9	-1.6	-2.9	-1.6	-1.7	-1.7
Angina	0.3	0.5	2.0	0.3	0.6	0.7	0.7	0.8	0.2	0.7	0.5	0.7	1.4	0.5	0.5	0.4
Trunk fat percentage	0.3	1.3	1.7	-1.2	-1.1	-1.3	-1.3	-1.1	-1.3	-1.3	-0.9	-1.1	0.9	-1.1	-1.2	-1.2
Average weekly fortified wine intake	0.3	0.4	1.2	0.7	0.6	0.4	0.4	0.2	0.9	0.4	1.1	0.3	-0.8	0.5	0.4	0.6
High blood pressure	0.3	0.7	5.3	0.4	0.2	0.5	0.5	0.8	0.6	0.5	0.2	0.9	2.3	0.6	0.5	0.4
Medication: Atenolol	0.3	0.3	0.8	0.2	0.4	0.6	0.6	0.6	0.5	0.6	0.8	0.5	0.9	0.6	0.5	0.4
Mouth/teeth dental problems	0.3	0.4	5.0	0.3	0.5	-0.0	-0.1	0.1	-0.0	-0.1	0.1	0.3	-2.2	0.0	-0.1	-0.1
Fluid intelligence score	0.3	0.7	1.0	0.9	0.7	0.8	0.8	0.8	1.0	0.8	1.0	0.8	0.9	0.8	0.8	0.8
Impedance of arm (right)	0.3	1.6	4.4	-1.1	-1.0	-1.0	-1.0	-1.1	-2.1	-1.0	-2.0	-1.4	0.7	-1.3	-1.1	-0.9
Time employed in main current job	0.3	0.4	1.2	0.5	0.6	0.6	0.6	0.6	0.5	0.6	0.6	0.7	1.1	0.5	0.5	0.6
Noisy workplace	0.3	0.3	2.1	0.2	0.4	0.5	0.5	0.5	0.2	0.5	0.6	0.6	1.4	0.5	0.4	0.4
Birth weight of first child	0.3	0.6	0.9	-0.8	-0.7	-0.8	-0.8	-0.7	-0.4	-0.8	-0.8	-0.7	-0.5	-0.8	-0.8	-1.0
Mouth/teeth dental problems: Loose teeth	0.3	0.4	2.4	0.1	-0.0	-0.1	-0.1	0.1	-0.1	-0.1	-1.5	0.1	1.5	-0.1	-0.2	0.1
Hypertension (Self-reported)	0.3	0.9	5.6	0.6	0.4	0.7	0.7	1.0	0.9	0.7	0.4	1.0	2.4	0.8	0.7	0.5
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	2.3	0.4	0.5	0.3	0.3	0.3	-0.2	0.3	1.0	0.2	1.5	0.4	0.4	0.2
Osteoporosis (self-reported)	0.3	0.4	1.7	-0.5	-0.5	-0.6	-0.6	-0.6	-0.3	-0.6	-1.3	-0.5	0.2	-0.7	-0.7	-0.8
Medication: Blood pressure	0.3	0.5	4.5	0.2	0.2	0.5	0.5	0.6	0.6	0.5	0.2	0.5	2.1	0.5	0.5	0.4
Leg fat percentage (left)	0.3	1.0	1.7	-1.3	-1.1	-1.1	-1.1	-1.0	-1.1	-1.1	-0.6	-0.9	0.0	-0.9	-1.0	-1.0
Unable to work because of sickness or disability	0.3	0.4	0.5	-0.6	-0.7	-0.7	-0.7	-0.6	-0.5	-0.7	-0.7	-0.6	-0.4	-0.6	-0.6	-0.6
Vascular/heart problems diagnosed by doctor	0.3	0.9	6.8	-0.5	-0.5	-0.7	-0.7	-1.0	-0.5	-0.7	-0.2	-1.0	-2.6	-0.7	-0.6	-0.5
Depressed Affect (Nagel 2018)	0.2	0.4	1.2	-0.9	-0.7	-0.5	-0.5	-0.4	-0.8	-0.4	-1.1	-0.6	0.0	-0.6	-0.4	-0.5
Alzheimer’s Disease (in mother)	0.2	0.3	1.0	0.7	0.6	0.5	0.5	0.5	-0.3	0.5	-0.2	0.3	1.0	0.4	0.6	0.6
Neuroticism (2016)	0.2	0.3	1.8	-0.5	-0.3	-0.4	-0.4	-0.4	-1.4	-0.4	-0.4	-0.8	0.3	-0.6	-0.4	-0.4
Primary Biliary Cirrhosis	0.2	0.3	1.3	0.5	0.8	0.3	0.3	0.3	0.1	0.3	1.1	0.5	-0.9	0.5	0.3	0.3
Ulcerative Colitis	0.2	0.3	1.4	-0.3	-0.3	-0.6	-0.6	-0.3	-0.2	-0.6	-0.2	-0.2	1.2	-0.2	-0.4	-0.5
Blood Red Count	0.2	2.0	3.9	-1.2	-1.4	-1.5	-1.5	-1.5	-0.3	-1.5	-2.0	-1.1	-1.7	-1.3	-1.5	-1.6
Allergy or Eczema	0.2	0.6	0.8	-0.5	-0.7	-0.8	-0.8	-0.8	-0.4	-0.8	-0.8	-0.9	-0.4	-0.9	-0.8	-0.9
Eye problems/disorders: Diabetes related eye disease	0.2	0.3	0.4	-0.6	-0.5	-0.6	-0.6	-0.5	-0.6	-0.6	0.4	-0.4	-0.0	-0.4	-0.5	-0.6
Fed-up feelings	0.2	0.3	0.9	-1.0	-0.8	-0.3	-0.3	-0.3	-0.8	-0.3	-0.8	-0.5	-0.7	-0.5	-0.4	-0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.4	1.5	-0.5	-0.5	-0.6	-0.6	-0.6	-0.4	-0.6	-1.2	-0.4	-0.9	-0.6	-0.6	-0.4
Father’s age at death	0.2	0.3	2.0	0.2	0.3	0.3	0.3	0.2	0.4	0.3	-0.3	0.3	-1.4	0.4	0.3	0.6
Worrier / anxious feelings	0.2	0.5	0.7	0.9	0.8	0.8	0.8	0.7	0.2	0.8	0.2	0.4	0.3	0.6	0.8	0.8
Medication: Cholesterol lowering	0.2	0.3	2.5	-0.0	0.2	0.0	0.0	0.1	-0.9	0.0	-0.4	0.0	1.6	-0.1	-0.1	-0.0
Medication: Lansoprazole	0.2	0.2	0.5	-0.1	-0.4	-0.5	-0.5	-0.5	-0.2	-0.5	0.1	-0.5	-0.5	-0.5	-0.6	-0.7
Lung cancer (father)	0.2	0.2	0.4	-0.6	-0.6	-0.4	-0.4	-0.5	-0.5	-0.4	-0.3	-0.5	-0.1	-0.5	-0.5	-0.5
Pulse wave Arterial Stiffness index	0.2	0.3	1.5	-0.4	-0.3	-0.4	-0.4	-0.6	0.2	-0.4	-0.1	-0.6	-1.2	-0.4	-0.4	-0.4
Tense / ‘highly strung’	0.2	0.4	3.2	-0.4	-0.3	0.3	0.3	0.2	-0.7	0.3	-0.4	-0.3	1.8	-0.3	0.1	-0.0
Loud music exposure frequency	0.2	0.2	2.8	0.0	0.0	0.1	0.1	0.0	0.3	0.1	-0.5	-0.0	1.7	0.0	0.1	0.1
Leg fat percentage (right)	0.2	0.8	1.2	-1.1	-0.8	-1.0	-1.0	-0.8	-1.0	-1.0	-0.8	-0.7	0.2	-0.8	-0.9	-0.8
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.3	2.6	0.2	0.4	0.5	0.5	0.4	-0.5	0.4	0.1	0.2	1.6	0.1	0.3	0.3
Medication: Seretide 50 evohaler	0.2	0.2	0.9	0.1	-0.0	-0.4	-0.4	-0.3	-0.9	-0.4	-0.6	-0.3	0.6	-0.5	-0.5	-0.7
Age at last live birth	0.2	0.3	0.5	-0.3	-0.3	-0.7	-0.7	-0.6	-0.3	-0.7	-0.7	-0.3	-0.0	-0.5	-0.6	-0.7
Medication: Gliclazide	0.2	0.2	0.6	0.1	0.4	0.2	0.2	0.4	0.7	0.2	0.8	0.6	-0.2	0.6	0.3	0.5
Guilty feelings	0.2	0.3	1.4	-0.5	-0.4	-0.3	-0.3	-0.4	-1.2	-0.3	-0.2	-0.7	0.9	-0.5	-0.3	-0.3
Medication: Bendroflumethiazide	0.2	0.3	2.4	-0.0	-0.0	0.2	0.2	0.5	0.2	0.2	-0.5	0.6	1.5	0.2	0.1	0.1
Medication: Lisinopril	0.2	0.3	3.1	-0.3	-0.1	-0.4	-0.4	-0.1	0.3	-0.4	-0.1	0.2	1.8	-0.0	-0.4	-0.4
Basal cell carcinoma (self-reported)	0.2	0.3	1.2	-0.4	-0.3	-0.5	-0.5	-0.4	-0.4	-0.5	0.1	-0.3	1.1	-0.3	-0.5	-0.8
Heart attack/myocardial infarction (self-reported)	0.2	0.3	1.3	0.5	0.6	0.5	0.5	0.5	-0.1	0.5	0.4	0.4	1.1	0.4	0.5	0.5
Deep venous thrombosis (DVT) (self-reported)	0.2	0.2	0.8	-0.7	-0.5	-0.4	-0.4	-0.3	-0.9	-0.4	-0.4	-0.5	0.4	-0.4	-0.4	-0.4
Impedance of whole body	0.2	0.8	2.7	-0.5	-0.5	-0.6	-0.6	-0.6	-1.4	-0.6	-1.6	-0.8	1.6	-0.8	-0.7	-0.4
Bipolar Disorder or Schizophrenia	0.1	0.1	0.2	0.2	0.3	0.4	0.4	0.4	0.2	0.4	0.3	0.4	0.4	0.3	0.4	0.3
Neuroticism (Nagel 2018)	0.1	0.2	0.4	-0.3	-0.0	0.5	0.5	0.2	-0.5	0.5	-0.6	-0.1	0.7	-0.2	0.1	0.2
Alzheimer’s Disease (in father)	0.1	0.1	0.3	-0.5	-0.2	-0.2	-0.2	-0.2	-0.6	-0.2	-0.1	-0.4	-0.2	-0.2	-0.1	-0.1
Alzheimer’s Disease (including proxy)	0.1	0.1	0.7	-0.1	-0.0	-0.2	-0.2	-0.1	-0.8	-0.2	-0.8	-0.3	0.3	-0.2	-0.0	-0.0
Major Depression (MDD)	0.1	0.1	0.2	-0.4	-0.2	-0.4	-0.4	-0.4	-0.3	-0.4	-0.2	-0.4	-0.2	-0.3	-0.3	-0.3
Reaction Time	0.1	0.2	0.4	0.4	0.2	0.5	0.5	0.5	0.6	0.5	0.3	0.5	0.0	0.6	0.6	0.5
Verbal and Numeric Reasoning (VNR)	0.1	0.1	0.5	0.6	0.3	0.3	0.3	0.4	0.1	0.3	0.7	0.3	0.4	0.3	0.3	0.3
Mean Putamen Volume	0.1	0.1	0.5	0.0	0.0	0.4	0.4	0.0	0.2	0.3	0.0	0.1	-0.7	-0.1	-0.0	0.3
LDL Cholesterol	0.1	0.2	2.0	0.1	0.1	-0.2	-0.2	0.1	-0.6	-0.1	-0.1	-0.1	1.4	0.0	0.1	-0.1
Blood White Count	0.1	0.6	1.1	0.6	0.6	0.8	0.8	0.9	0.3	0.8	-0.0	1.0	1.0	0.8	0.8	0.8
BMI	0.1	0.9	1.7	-1.3	-1.1	-1.0	-1.0	-1.0	-0.7	-1.0	-0.3	-0.8	-0.5	-0.8	-1.0	-1.0
Hair Pigment	0.1	2.3	3.4	-1.6	-1.9	-1.6	-1.6	-1.6	-0.6	-1.6	-1.8	-1.6	-0.6	-1.6	-1.5	-1.6
Average weekly spirits intake	0.1	0.2	0.9	-0.5	-0.2	-0.2	-0.2	-0.2	-1.0	-0.2	-0.2	-0.2	0.7	-0.4	-0.4	-0.3
Sensitivity / hurt feelings	0.1	0.3	2.4	0.1	0.2	0.4	0.4	0.1	-0.2	0.4	0.3	-0.1	-1.6	0.1	0.3	0.4
Systolic blood pressure, automated reading	0.1	0.3	1.4	0.5	0.4	0.3	0.3	0.5	0.2	0.3	0.7	0.8	1.2	0.5	0.2	0.1
Supplements: Zinc	0.1	0.1	0.9	-0.1	-0.1	0.0	0.0	-0.0	-0.4	0.0	0.1	-0.1	-1.0	-0.0	0.0	0.0
Impedance of leg (right)	0.1	0.3	2.0	0.4	0.3	0.2	0.2	0.2	-0.9	0.2	-1.1	0.0	1.4	-0.1	0.1	0.4
Townsend deprivation index at recruitment	0.1	0.1	0.4	-0.6	-0.6	-0.2	-0.2	-0.4	0.0	-0.2	-0.2	-0.5	0.2	-0.3	-0.2	-0.1
Maternal smoking around birth	0.1	0.1	0.5	-0.3	-0.4	-0.2	-0.2	-0.2	-0.1	-0.2	0.2	-0.1	-0.7	-0.1	-0.2	-0.2
Age when periods started (menarche)	0.1	0.2	1.9	-0.1	-0.1	-0.1	-0.1	-0.1	-0.6	-0.1	0.0	-0.3	1.4	-0.2	-0.1	-0.2
Hayfever, allergic rhinitis or eczema	0.1	0.2	0.6	-0.1	-0.4	-0.3	-0.3	-0.5	0.2	-0.3	-0.8	-0.5	-0.4	-0.5	-0.4	-0.4
Stomach or abdominal pain in last month	0.1	0.1	0.5	-0.0	0.2	0.4	0.4	0.4	-0.2	0.4	0.2	0.3	0.7	0.2	0.3	0.3
Chronic bronchitis/emphysema (father)	0.1	0.2	1.5	0.1	0.3	-0.1	-0.1	0.0	-0.5	-0.1	-0.4	0.1	1.2	-0.1	-0.2	-0.2
Body mass index (BMI)	0.1	0.5	0.9	-1.0	-0.7	-0.8	-0.8	-0.7	-0.5	-0.8	-0.2	-0.6	-0.4	-0.6	-0.7	-0.8
Impedance of leg (left)	0.1	0.3	1.3	-0.0	-0.1	-0.2	-0.2	-0.2	-1.0	-0.2	-1.0	-0.4	1.1	-0.4	-0.2	0.1
Ever unenthusiastic/disinterested for a whole week	0.1	0.1	0.3	0.3	0.4	0.3	0.3	0.1	-0.3	0.2	0.6	-0.0	-0.1	0.1	0.2	0.2
Allergy	0.1	0.3	0.5	0.3	0.6	0.6	0.6	0.6	-0.1	0.6	0.7	0.6	0.7	0.6	0.6	0.6
Medication: Ramipril	0.1	0.2	1.3	0.2	0.1	0.3	0.3	0.4	0.2	0.3	-0.4	0.4	1.1	0.2	0.3	0.1
Neuroticism score	0.1	0.1	0.3	0.1	0.2	0.5	0.5	0.4	-0.5	0.5	-0.2	-0.1	0.2	0.1	0.4	0.4
Pulse rate	0.1	0.1	0.3	0.1	-0.0	-0.3	-0.3	-0.3	0.6	-0.3	-0.4	-0.3	-0.2	-0.3	-0.3	-0.4
Mouth/teeth dental problems: Dentures	0.1	0.2	2.0	-0.0	-0.0	0.4	0.4	0.3	0.3	0.4	0.4	0.2	1.4	0.3	0.4	0.4
Pulse wave reflection index	0.1	0.2	0.5	-0.7	-0.5	-0.4	-0.4	-0.5	0.2	-0.4	-0.3	-0.3	-0.6	-0.2	-0.4	-0.3
Qualifications: O levels/GCSEs or equivalent	0.1	0.2	0.9	0.5	0.3	0.2	0.2	0.2	0.7	0.2	0.9	0.3	0.6	0.4	0.2	0.3
Mouth/teeth dental problems: Bleeding gums	0.1	0.2	1.0	0.3	-0.0	0.4	0.4	0.4	0.6	0.4	-0.0	0.3	1.0	0.3	0.4	0.3
Blood clot in the leg (DVT)	0.1	0.1	0.5	-0.5	-0.3	-0.3	-0.3	-0.2	-0.7	-0.3	-0.1	-0.3	0.7	-0.3	-0.3	-0.3
Headache pain in last month	0.1	0.1	0.3	-0.1	-0.2	-0.3	-0.3	-0.3	-0.6	-0.3	-0.4	-0.4	0.0	-0.4	-0.3	-0.2
Gout (self-reported)	0.1	0.1	0.7	0.2	0.0	0.1	0.1	0.1	-0.4	0.0	0.3	0.1	0.8	-0.0	-0.1	-0.0
Exposure to tobacco smoke outside home	0.1	0.1	0.6	-0.5	-0.3	-0.1	-0.1	-0.2	-0.1	-0.1	0.8	-0.1	0.1	0.0	-0.1	-0.1
Number of full brothers	0.1	0.1	1.3	-0.0	0.0	0.1	0.1	0.1	-0.3	0.1	-1.1	-0.0	-0.4	-0.2	-0.0	0.1
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.1	0.5	-0.5	-0.6	-0.1	-0.1	-0.2	-0.6	-0.1	-0.7	-0.4	0.1	-0.3	-0.2	-0.2
Age at first live birth	0.1	0.1	0.3	0.1	-0.0	-0.5	-0.5	-0.4	0.1	-0.5	-0.4	-0.2	-0.0	-0.2	-0.4	-0.5
Health satisfaction	0.1	0.1	0.3	-0.4	-0.5	-0.3	-0.3	-0.3	0.0	-0.3	0.4	-0.3	0.5	-0.2	-0.2	-0.3
Shortness of breath walking on level ground	0.1	0.1	0.2	-0.1	-0.2	-0.1	-0.1	-0.2	-0.1	-0.1	-0.5	-0.4	0.5	-0.3	-0.1	-0.2
Emphysema/chronic bronchitis	0.1	0.1	0.4	0.6	0.6	0.1	0.1	0.2	0.3	0.1	-0.1	0.2	-0.3	0.1	0.1	-0.1
Mean time to correctly identify matches	0.1	0.2	0.5	-0.7	-0.7	-0.4	-0.4	-0.4	-0.4	-0.4	-0.1	-0.5	-0.2	-0.3	-0.3	-0.3
Number of full sisters	0.1	0.1	0.2	-0.5	-0.5	-0.3	-0.3	-0.3	-0.2	-0.3	-0.3	-0.3	0.3	-0.3	-0.3	-0.2
Had major operations	0.1	0.2	0.2	-0.4	-0.3	-0.5	-0.5	-0.4	-0.4	-0.5	0.0	-0.3	0.5	-0.4	-0.5	-0.5
Family relationship satisfaction	0.1	0.1	0.2	0.2	0.2	0.3	0.3	0.3	-0.0	0.3	0.4	0.2	-0.2	0.2	0.3	0.5
Smoking status: Previous	0.1	0.1	0.7	-0.3	-0.1	0.2	0.2	0.2	0.5	0.2	0.8	0.2	-0.1	0.3	0.2	0.3
Mouth/teeth dental problems: Mouth ulcers	0.1	0.2	1.0	0.4	0.3	0.3	0.3	0.2	0.7	0.3	1.0	0.2	0.6	0.4	0.3	0.2
Back pain experienced in last month	0.1	0.1	0.5	0.3	0.3	0.3	0.3	0.3	0.7	0.3	-0.6	0.4	-0.2	0.2	0.2	0.3
Mineral and other dietary supplements	0.1	0.1	0.7	0.1	0.1	-0.0	-0.0	0.0	0.4	-0.0	0.3	0.1	-0.8	0.2	0.1	0.2
Average weekly champagne plus white wine intake	0.1	0.2	0.6	-0.2	-0.4	-0.4	-0.4	-0.4	-0.4	-0.4	-0.2	-0.3	0.8	-0.3	-0.4	-0.4
Mother’s age at death	0.1	0.1	1.3	-0.0	0.3	-0.1	-0.1	0.2	-0.2	-0.0	-0.6	0.1	1.1	0.0	-0.0	-0.1
Financial situation satisfaction	0.1	0.1	0.2	0.0	-0.0	0.3	0.3	0.2	0.3	0.3	-0.0	0.3	-0.1	0.3	0.3	0.4
Medication: Paracetamol	0.1	0.2	0.5	-0.6	-0.4	-0.4	-0.4	-0.5	-0.5	-0.4	-0.4	-0.5	-0.7	-0.4	-0.4	-0.3
Diastolic blood pressure, automated reading	0.1	0.2	0.6	0.5	0.4	0.3	0.3	0.6	0.7	0.3	0.6	0.8	-0.4	0.5	0.3	0.2
Ever depressed for a whole week	0.1	0.1	0.7	0.2	0.2	0.2	0.2	0.1	-0.2	0.2	0.1	0.0	-0.8	0.0	0.2	0.2
Commuting to job workplace: Cycle	0.1	0.2	0.3	0.6	0.2	0.4	0.4	0.4	0.5	0.4	0.1	0.3	0.4	0.3	0.4	0.4
Alcohol drinker status: Previous	0.1	0.1	0.7	0.2	0.1	0.2	0.2	0.1	-0.2	0.2	0.8	-0.0	0.0	0.1	0.2	0.1
Prostate Cancer	0.0	0.1	0.4	-0.0	-0.2	-0.1	-0.1	-0.2	0.6	-0.1	-0.5	-0.1	0.2	-0.1	-0.1	-0.2
Crohns Disease (2012)	0.0	0.1	0.3	0.1	0.4	0.2	0.2	0.1	-0.6	0.2	-0.3	0.0	0.3	-0.0	0.1	0.2
HDL Cholesterol	0.0	0.1	0.1	0.1	0.2	-0.3	-0.3	-0.1	-0.3	-0.2	-0.2	-0.3	-0.2	-0.3	-0.2	-0.3
Lupus	0.0	0.1	0.2	-0.2	0.1	0.2	0.2	0.4	0.4	0.2	-0.3	0.4	-0.2	0.2	0.2	0.1
Blood Eosinophil Count	0.0	0.2	1.2	0.4	0.4	0.2	0.2	0.0	-0.7	0.2	1.1	-0.2	-1.0	-0.0	0.2	0.2
Blood Platelet Count	0.0	0.4	0.9	-0.3	-0.4	-0.7	-0.7	-0.7	-0.9	-0.7	-0.1	-0.7	0.4	-0.6	-0.6	-0.5
Lung FEV1/FVC ratio	0.0	0.1	0.4	0.0	0.1	-0.3	-0.3	-0.2	-0.5	-0.3	0.3	-0.2	0.0	-0.3	-0.3	-0.6
Neuroticism	0.0	0.1	0.3	0.1	0.2	0.4	0.4	0.3	-0.4	0.4	-0.1	-0.0	0.5	0.1	0.3	0.2
Chronotype (morning person)	0.0	0.1	0.9	0.2	0.2	0.3	0.3	0.1	1.0	0.2	-0.1	0.2	-0.4	0.1	0.1	0.0
Ever had hysterectomy (womb removed)	0.0	0.1	0.4	-0.1	0.1	0.2	0.2	0.1	0.2	0.2	0.1	0.0	0.6	0.2	0.3	0.2
Bilateral oophorectomy (both ovaries removed)	0.0	0.0	0.2	-0.4	-0.2	0.0	0.0	-0.1	-0.4	0.0	-0.4	-0.1	0.2	-0.0	0.0	0.1
Trunk fat mass	0.0	0.1	0.3	-0.3	-0.1	-0.4	-0.4	-0.2	-0.2	-0.4	0.3	-0.0	0.6	-0.1	-0.3	-0.4
Waist circumference	0.0	0.1	0.5	-0.1	0.1	0.0	0.0	0.1	0.3	0.0	0.7	0.3	0.1	0.3	0.1	-0.0
Past tobacco smoking	0.0	0.1	0.3	0.5	0.3	0.0	0.0	0.1	-0.0	0.0	-0.6	0.1	0.6	-0.0	0.0	0.0
Alcohol usually taken with meals	0.0	0.0	0.1	0.0	-0.1	-0.3	-0.3	-0.2	0.2	-0.3	0.3	-0.1	0.3	-0.1	-0.2	-0.3
Hearing difficulty/problems with background noise	0.0	0.1	0.3	0.1	0.1	0.2	0.2	0.0	0.5	0.2	0.4	-0.0	-0.5	0.1	0.2	0.2
Hip circumference	0.0	0.2	0.4	-0.4	-0.2	-0.4	-0.4	-0.3	-0.1	-0.4	-0.2	-0.2	0.7	-0.3	-0.4	-0.6
Alcohol intake versus 10 years previously	0.0	0.1	0.1	-0.0	0.2	0.3	0.3	0.2	0.0	0.3	-0.4	-0.0	0.4	0.1	0.3	0.4
Frequency of tiredness / lethargy in last 2 weeks	0.0	0.0	0.1	-0.1	-0.2	0.1	0.1	0.1	-0.0	0.1	-0.1	0.0	0.3	0.0	0.1	0.1
Arm fat mass (right)	0.0	0.1	0.3	-0.5	-0.3	-0.5	-0.5	-0.4	-0.3	-0.5	0.2	-0.3	0.1	-0.3	-0.4	-0.5
Birth weight	0.0	0.1	0.4	0.1	0.0	-0.0	-0.0	0.0	0.6	-0.0	-0.2	0.2	0.6	0.1	0.0	-0.2
Chronic bronchitis/emphysema (mother)	0.0	0.1	0.1	0.3	0.3	0.3	0.3	0.3	-0.2	0.3	0.1	0.2	-0.0	0.2	0.2	0.3
High blood pressure (siblings)	0.0	0.1	0.5	-0.1	0.1	-0.1	-0.1	0.1	0.2	-0.1	-0.3	0.2	0.7	0.1	-0.0	-0.0
Comparative body size at age 10	0.0	0.1	0.5	0.1	0.0	-0.3	-0.3	-0.3	-0.4	-0.2	0.6	-0.3	0.7	-0.0	-0.1	-0.1
Medication for pain relief, constipation, heartburn	0.0	0.0	0.1	0.3	-0.0	-0.0	-0.0	-0.0	0.2	-0.0	-0.3	0.1	-0.2	-0.0	-0.1	-0.2
Migraine (self-reported)	0.0	0.0	0.1	-0.1	-0.3	-0.2	-0.2	-0.2	-0.2	-0.2	-0.2	-0.3	-0.4	-0.2	-0.1	0.0
Whole body fat mass	0.0	0.0	0.2	-0.2	0.0	-0.2	-0.2	-0.0	0.0	-0.2	0.3	0.1	0.4	0.0	-0.1	-0.2
Leg fat mass (right)	0.0	0.1	0.1	-0.4	-0.1	-0.3	-0.3	-0.2	-0.1	-0.3	0.3	-0.0	0.1	-0.1	-0.3	-0.3
Loneliness, isolation	0.0	0.0	0.3	-0.1	-0.1	0.2	0.2	0.1	-0.5	0.2	-0.3	-0.2	0.0	-0.2	0.1	0.1
Qualifications: nursing, teaching	0.0	0.0	0.3	0.2	0.0	-0.1	-0.1	0.0	0.5	-0.1	-0.1	0.2	-0.2	0.0	-0.1	-0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.0	0.0	0.1	0.0	0.1	-0.1	-0.1	-0.0	-0.3	-0.1	-0.3	0.1	0.4	0.0	-0.0	-0.1
Arm fat mass (left)	0.0	0.1	0.3	-0.5	-0.3	-0.5	-0.5	-0.3	-0.3	-0.5	0.3	-0.2	0.0	-0.3	-0.4	-0.5
Miserableness	0.0	0.1	0.4	-0.3	-0.1	-0.0	-0.0	-0.0	-0.3	-0.0	-0.6	-0.3	0.6	-0.2	-0.1	-0.1
Ever smoked	0.0	0.1	0.3	-0.4	-0.4	-0.0	-0.0	-0.0	-0.1	-0.0	0.4	-0.1	-0.5	0.0	-0.0	0.1
Fractured/broken bones in last 5 years	0.0	0.0	0.3	-0.1	-0.1	0.1	0.1	0.0	-0.0	0.1	-0.4	-0.1	0.5	-0.1	-0.0	-0.0
Leg fat mass (left)	0.0	0.1	0.2	-0.4	-0.1	-0.3	-0.3	-0.2	-0.1	-0.3	0.4	-0.0	0.0	-0.1	-0.2	-0.3

Hub : Genes

EFCAB1

Models

Trait associations