TWAS hub - EFTUD1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0570	0.0270	5.1e-03	0.020	0.014	0.020	0.016	0.021	1.6e-03	6.0e-03	1.4e-03	0.0036	1.3e-03
2	GTEx	Cells Transformed fibroblasts	0.1730	0.0420	1.4e-08	0.116	NA	0.132	NA	0.142	5.2e-09	NA	4.6e-10	NA	9.0e-11
3	GTEx	Esophagus Mucosa	0.0890	0.0350	8.8e-04	0.061	NA	0.076	NA	0.063	6.7e-05	NA	9.0e-06	NA	4.8e-05
4	GTEx	Heart Atrial Appendage	0.2070	0.0670	2.7e-05	0.114	NA	0.117	NA	0.112	8.8e-06	NA	6.3e-06	NA	9.8e-06
5	GTEx	Muscle Skeletal	0.0849	0.0276	9.7e-06	0.017	NA	0.053	NA	0.042	8.2e-03	NA	6.3e-06	NA	5.7e-05
6	GTEx	Nerve Tibial	0.1849	0.0580	6.6e-05	0.002	NA	0.037	NA	0.030	2.1e-01	NA	1.3e-03	NA	3.3e-03
7	GTEx	Skin Sun Exposed Lower leg	0.0630	0.0270	3.7e-03	0.033	NA	0.036	NA	0.043	9.1e-04	NA	5.1e-04	NA	1.7e-04
8	GTEx	Testis	0.3520	0.0750	1.4e-07	0.126	NA	0.209	NA	0.200	3.3e-06	NA	1.2e-09	NA	2.9e-09
9	GTEx	Uterus	0.5180	0.1570	1.7e-03	0.003	NA	0.017	NA	-0.003	2.8e-01	NA	1.4e-01	NA	3.7e-01
10	TCGA	Kidney Renal Clear Cell Carcinoma	0.0607	0.0221	1.5e-06	0.022	0.055	0.050	NA	0.037	1.4e-03	7.3e-07	2.3e-06	NA	4.6e-05
11	TCGA	Brain Lower Grade Glioma	0.0356	0.0197	6.7e-03	0.006	0.006	0.014	NA	0.005	6.7e-02	6.5e-02	9.2e-03	NA	7.0e-02
12	TCGA	Ovarian Serous Cystadenocarcinoma	0.0550	0.0320	7.4e-03	0.024	0.018	-0.003	NA	0.006	8.8e-03	2.1e-02	6.3e-01	NA	1.1e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12
Prospective memory result	9.5	11.7	23.0	-1.1	-4.8	-4.2	-3.9	-3.0	-1.5	-0.5	-4.6	-1.4	-4.6	-2.7	-4.5
Commuting to job workplace: Public transport	9.5	11.3	24.7	2.0	3.9	4.0	4.0	5.0	2.6	-0.9	2.8	1.2	4.3	3.3	3.6
Intelligence (Savage-Jansen 2018)	6.1	18.8	43.0	1.4	5.3	5.5	4.6	5.6	1.2	-1.6	3.9	1.8	6.6	4.0	5.5
Alcohol usually taken with meals	5.2	8.4	20.9	1.7	3.9	3.6	3.6	4.6	1.5	0.2	2.8	-0.6	3.4	0.8	3.6
Seen doctor (GP) for nerves, anxiety, tension or depression	5.1	7.8	16.8	0.5	3.1	3.0	4.0	3.2	2.0	-0.7	2.9	0.4	4.1	2.0	3.7
Reason for reducing amount of alcohol drunk: Health precaution	4.8	5.6	10.8	1.4	3.3	2.8	1.5	2.0	3.0	2.9	3.1	0.4	2.1	1.5	2.5
Illnesses of siblings	4.6	6.5	13.0	0.7	2.5	2.7	1.2	3.0	1.6	0.8	2.6	3.6	3.4	3.3	2.8
Comparative body size at age 10	4.6	12.7	23.5	-3.2	-4.4	-4.1	-3.4	-4.8	-3.1	-0.4	-3.8	-2.0	-4.7	-2.3	-4.2
Chest pain or discomfort	4.5	6.4	12.4	2.0	3.2	3.2	2.7	2.0	1.8	1.5	3.5	-1.0	3.3	1.7	3.0
Illnesses of siblings: Diabetes	4.5	5.5	9.9	-1.8	-2.7	-3.2	-1.5	-2.8	-1.9	-1.7	-2.4	-1.7	-2.1	-3.1	-2.5
Angina (self-reported)	4.2	5.5	9.8	-0.1	-2.6	-2.6	-1.6	-2.0	-2.0	-1.0	-2.8	-3.1	-2.5	-3.1	-2.7
Angina	4.0	5.3	10.4	-0.2	-2.4	-2.6	-1.7	-2.0	-1.7	-0.8	-2.7	-3.2	-2.4	-3.1	-2.6
Frequency of tenseness / restlessness in last 2 weeks	3.8	5.9	12.0	0.7	2.7	2.9	3.3	2.2	1.3	-0.2	2.8	0.2	3.5	2.4	3.4
Frequency of tiredness / lethargy in last 2 weeks	3.8	6.1	15.7	0.7	2.6	2.8	2.4	2.6	1.8	-0.8	2.7	1.6	4.0	2.3	3.3
Vitamin and mineral supplements	3.6	4.8	9.8	-0.5	-2.8	-2.9	-1.7	-3.0	-0.4	1.0	-1.9	-1.3	-2.8	-3.1	-2.5
Fluid intelligence score	3.6	7.5	13.9	1.3	3.7	3.7	3.5	3.2	1.2	0.1	2.9	0.3	3.6	1.5	3.7
Alcohol drinker status: Never	3.5	4.2	8.6	1.7	1.8	1.6	2.1	2.6	0.5	-1.8	1.8	2.1	2.9	2.0	2.7
Supplements: Vitamin C	3.4	4.0	7.4	0.8	2.7	2.2	2.1	2.7	0.9	-0.2	2.2	0.6	2.0	2.7	2.6
Stomach or abdominal pain in last month	3.2	3.9	13.2	-0.0	2.3	2.2	3.6	2.0	2.0	1.7	1.7	-1.7	1.5	1.5	1.8
Depression (self-reported)	3.2	3.9	8.0	1.6	2.5	1.9	2.8	2.0	1.9	0.1	2.4	0.7	2.2	1.1	2.5
Qualifications: College or University degree	3.2	10.0	27.8	1.7	4.0	3.7	5.3	4.6	1.4	-0.9	3.4	0.5	3.0	2.3	3.1
Qualifications: None of the above	3.1	6.7	12.2	-0.8	-3.2	-3.0	-3.5	-2.8	-0.1	0.3	-3.2	-1.5	-3.1	-2.9	-3.1
Schizophrenia (2018)	3.0	6.2	14.8	-3.5	-3.1	-3.9	-1.8	-1.7	-1.9	-2.5	-2.4	-0.5	-2.3	-1.9	-2.5
Verbal and Numeric Reasoning (VNR)	3.0	7.3	15.3	2.1	3.2	3.6	3.9	3.5	0.3	-1.1	2.1	1.1	3.8	1.3	3.1
Diabetes (father)	3.0	3.7	6.2	-2.0	-2.4	-2.2	-1.0	-2.5	-1.2	-0.6	-1.8	-1.3	-1.8	-2.4	-2.5
Pulse wave reflection index	2.9	3.5	9.1	-1.1	-1.8	-1.8	-3.0	-2.2	-1.1	0.4	-2.0	-1.9	-2.2	-1.5	-2.2
Smoking status: Current	2.9	4.6	16.2	-0.1	-2.6	-2.8	-4.0	-3.0	-0.6	0.8	-1.6	-1.1	-2.2	-1.5	-2.0
Diverticular disease/diverticulitis (self-reported)	2.8	3.3	7.2	1.6	1.9	2.0	1.9	0.7	1.8	1.9	2.6	0.3	2.7	0.8	2.0
Noisy workplace	2.8	3.4	7.5	2.4	-1.9	-2.2	-0.4	-1.9	0.5	-0.6	-1.1	-1.2	-2.6	-2.7	-2.3
Number of incorrect matches in round	2.7	4.4	7.5	-1.8	-2.4	-2.7	-1.5	-2.7	-2.5	-0.1	-2.1	-1.9	-2.7	-1.1	-2.1
Number of live births	2.7	3.8	6.9	-2.6	-2.3	-2.4	-1.3	-2.3	-1.8	-0.0	-2.3	-1.0	-2.1	-1.1	-2.2
Smoking Status	2.6	6.2	21.0	-1.3	-2.9	-2.9	-4.6	-3.4	-0.4	1.1	-2.1	-0.9	-2.7	-1.5	-2.6
Current tobacco smoking	2.6	4.2	14.2	0.1	-2.4	-2.7	-3.8	-2.8	-0.6	1.0	-1.5	-1.0	-2.2	-1.5	-1.9
Average weekly fortified wine intake	2.6	3.1	8.0	0.3	1.1	1.2	2.5	2.8	-0.7	-2.8	0.4	1.2	2.1	1.7	1.6
Bipolar Disorder or Schizophrenia	2.5	6.1	16.5	-2.2	-3.4	-4.1	-1.6	-1.6	-1.9	-2.6	-2.4	-1.0	-2.9	-1.8	-2.5
Qualifications: A levels/AS levels or equivalent	2.5	5.4	12.6	2.0	3.2	2.8	3.0	3.5	1.1	0.2	2.3	0.7	2.3	1.8	2.4
Forced expiratory volume in 1-second (FEV1), Best measure	2.5	8.0	18.9	2.2	3.8	3.2	2.6	2.2	2.1	1.3	4.3	1.6	3.6	1.6	3.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.5	5.3	9.0	2.1	2.9	3.0	2.2	1.7	1.9	1.1	2.8	2.6	2.6	1.9	2.1
Mother’s age at death	2.5	3.1	8.8	0.3	1.7	2.1	1.3	2.5	0.8	-0.7	1.1	1.9	1.6	3.0	2.0
Hair/balding pattern: Pattern 2	2.4	3.0	8.6	0.7	2.4	1.6	0.3	0.8	1.5	2.7	2.9	-1.3	1.2	0.8	2.2
Peak expiratory flow (PEF)	2.3	5.3	12.1	1.4	2.8	2.7	3.5	3.5	1.4	-0.3	2.3	1.1	2.8	1.0	2.4
High blood pressure (siblings)	2.3	3.3	9.6	0.1	-1.3	-1.4	-0.9	-2.3	-1.4	-0.1	-1.2	-3.1	-2.9	-2.1	-2.0
Supplements: Calcium	2.3	2.5	7.4	0.4	1.4	1.6	1.2	2.2	0.9	-0.5	1.4	1.2	2.0	2.7	1.9
Medication: Co-codamol	2.2	2.6	7.0	-2.3	-2.2	-1.3	-0.6	-1.1	-1.4	-1.4	-2.6	-0.2	-1.7	-0.9	-1.8
Hair/balding pattern: Pattern 4	2.2	5.2	9.4	-1.8	-3.0	-2.7	-1.4	-2.1	-2.8	-2.6	-3.1	1.0	-1.6	-1.2	-2.8
Qualifications: NVQ or HND or HNC or equivalent	2.2	2.7	13.3	-1.9	-1.6	-0.8	-3.6	-0.8	-1.0	1.6	-1.9	-0.6	-1.2	0.7	-1.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.2	2.5	5.8	-2.4	-1.9	-2.1	-1.9	-1.5	-1.2	-0.2	-1.1	-1.3	-1.2	-1.4	-1.6
Financial difficulties in last 2 years	2.1	2.9	8.2	-0.8	1.4	1.5	0.4	2.0	1.4	-0.4	1.1	1.4	2.9	2.8	2.1
Forced expiratory volume in 1-second (FEV1)	2.1	6.9	11.9	2.9	3.5	3.1	2.5	2.7	2.0	0.6	3.3	1.8	3.4	1.2	2.9
Commuting to job workplace: Walk	2.1	2.3	4.3	1.2	2.0	2.1	1.7	1.2	-0.2	-0.5	1.9	0.0	2.1	1.6	1.7
Back pain experienced in last month	2.1	3.1	7.5	-0.1	-2.7	-2.2	-1.9	-1.3	-1.2	-0.4	-2.4	-1.1	-1.3	-2.2	-2.0
Wears glasses or contact lenses	2.0	2.3	5.7	-0.5	1.9	1.7	2.3	1.3	1.1	0.3	2.0	-0.8	1.5	0.1	2.4
Blood Red Count	1.9	18.0	38.8	-0.8	5.0	5.7	4.7	2.9	2.0	1.9	5.4	-1.9	6.2	3.5	6.0
Past tobacco smoking	1.9	3.5	11.1	0.5	2.0	2.3	3.3	2.4	-0.0	-1.1	1.4	1.3	2.0	1.3	2.3
Qualifications: O levels/GCSEs or equivalent	1.9	3.0	8.3	1.1	2.1	2.4	1.0	2.9	0.3	0.3	1.3	1.2	1.8	2.2	1.8
Worry too long after embarrassment	1.9	3.2	7.8	-0.1	1.8	1.8	2.8	2.1	0.3	-1.4	1.7	-0.9	2.6	1.4	2.2
Serious illness, injury or assault to yourself	1.8	2.2	4.4	2.0	1.0	1.6	1.4	0.3	1.8	1.8	1.3	1.1	1.4	2.1	0.8
Lung cancer (father)	1.8	2.1	4.9	0.1	-2.2	-1.6	-1.9	-2.2	-0.4	-0.0	-1.6	0.4	-1.6	-0.2	-1.8
Migraine (self-reported)	1.8	2.3	3.3	1.4	1.8	1.8	1.4	1.6	1.4	-0.2	1.6	0.8	1.7	1.7	1.7
Commuting to job workplace: Car/motor vehicle	1.8	2.1	4.5	-1.4	-1.8	-1.1	-2.0	-2.1	-0.6	0.4	-1.7	1.8	-1.6	0.1	-1.0
Supplements: Fish oil (including cod liver oil)	1.8	2.3	9.2	-1.3	1.9	2.2	-0.7	1.3	0.1	0.4	1.3	-0.1	1.5	3.0	1.3
Hayfever/allergic rhinitis (self-reported)	1.7	2.3	5.9	-1.6	-1.9	-2.4	-1.2	-1.4	-0.9	-2.1	-1.2	1.2	-0.9	-0.7	-1.5
Serious illness, injury or assault of a close relative in last 2 years	1.7	1.9	4.2	0.0	1.5	1.6	1.7	1.1	0.4	0.6	1.8	0.0	2.0	1.9	1.7
Mouth/teeth dental problems: Dentures	1.7	2.9	7.4	-1.6	-1.6	-1.5	-1.4	-1.2	-0.3	-0.3	-2.3	-2.1	-2.7	-1.4	-2.0
Medication: Lansoprazole	1.7	1.9	6.1	0.8	1.7	1.8	0.3	1.6	2.5	1.8	1.0	-0.9	1.3	0.3	0.9
Forced vital capacity (FVC), Best measure	1.7	6.1	15.3	1.3	3.3	2.9	1.5	1.7	1.6	1.5	3.9	1.4	3.0	2.3	3.3
Knee pain experienced in last month	1.7	2.6	5.1	0.1	1.9	1.9	2.1	1.5	1.2	0.3	1.7	0.3	2.2	1.6	2.2
Diastolic blood pressure, automated reading	1.7	5.3	11.7	-3.1	-3.0	-3.0	-1.1	-2.6	-3.4	-2.0	-2.0	-0.8	-1.8	-0.7	-1.9
Tanning	1.6	19.9	39.6	-2.8	-5.4	-5.5	-3.7	-5.4	-4.0	-0.0	-4.5	-1.4	-6.3	-3.8	-5.9
Bilateral oophorectomy (both ovaries removed)	1.6	1.9	4.7	0.0	2.2	2.1	0.5	1.2	1.0	1.5	1.7	-0.8	0.8	1.4	1.4
Illnesses of mother	1.6	2.0	3.8	-0.4	-1.9	-1.7	-1.3	-1.4	-1.3	-0.8	-1.9	0.6	-1.9	-0.7	-1.8
Illnesses of father: None of the above (group 1)	1.6	2.0	5.3	0.0	1.7	1.2	0.2	1.4	1.9	2.3	1.7	0.4	1.3	1.6	1.3
Leg fat percentage (left)	1.6	5.9	12.1	-1.2	-3.5	-3.1	-1.3	-3.0	-2.4	-2.0	-2.7	-0.9	-2.2	-2.7	-2.7
Rheumatoid Arthritis	1.5	2.1	7.8	0.4	-1.0	-1.4	-2.0	-1.1	-2.1	0.2	-1.0	-1.4	-0.7	-2.8	-1.0
Schizophrenia (2014)	1.5	3.4	10.5	-2.0	-2.5	-3.2	-0.4	-1.6	-1.4	-3.1	-1.5	0.5	-0.9	-0.3	-1.1
Tinnitus: Yes, but not now, but have in the past	1.5	1.7	4.1	-0.1	-1.6	-1.3	0.2	-1.2	-2.0	-1.9	-1.5	-0.6	-1.3	-1.1	-0.8
Multivitamins +/- minerals	1.5	1.9	4.5	-0.4	1.6	1.8	0.7	1.7	-0.1	-0.9	1.0	1.4	2.1	2.1	1.2
Illness, injury, bereavement, stress in last 2 years	1.5	1.8	8.3	-0.5	-0.9	-1.4	-0.3	0.4	-1.5	-1.2	-1.2	-1.5	-1.3	-2.9	-1.1
Smoking status: Previous	1.5	2.3	5.4	-1.2	-1.6	-1.7	-2.3	-1.8	-0.0	0.8	-1.4	-0.7	-1.7	-1.1	-2.0
Tinnitus: Yes, now most or all of the time	1.5	1.7	5.2	0.5	1.3	1.6	1.6	2.3	1.3	-0.7	1.1	-0.3	1.7	1.0	0.9
Ever smoked	1.5	2.6	8.5	-0.4	-1.7	-2.1	-2.9	-2.4	-0.5	0.5	-1.0	-0.7	-1.6	-1.3	-1.8
Leg fat mass (left)	1.5	5.7	9.9	-2.3	-3.1	-3.0	-1.7	-3.1	-2.8	-1.5	-2.4	-0.9	-1.7	-2.4	-2.4
Age when periods started (menarche)	1.4	3.5	8.5	2.9	-0.3	0.2	2.8	1.7	0.3	-2.8	0.6	2.9	1.6	0.6	1.5
Time employed in main current job	1.4	1.7	4.6	0.6	-0.9	-0.5	-0.2	-1.1	-1.5	-0.0	-1.6	-2.1	-1.6	-1.9	-1.4
Father’s age at death	1.4	1.9	5.2	0.4	2.3	2.1	1.7	0.9	-0.3	-0.3	1.5	0.7	1.0	1.4	1.7
Medication: Amlodipine	1.4	2.0	5.3	1.5	1.6	1.6	-0.2	0.7	1.9	2.3	2.0	-1.1	1.0	0.1	1.1
Leg fat percentage (right)	1.4	5.1	10.3	-1.2	-3.2	-2.9	-1.2	-2.9	-2.5	-1.9	-2.4	-1.0	-1.9	-2.2	-2.5
Number of children fathered	1.4	1.6	5.0	-0.9	-0.4	-0.7	-1.8	-1.0	1.3	2.2	0.3	-1.8	-1.2	-1.2	-0.7
Commuting to job workplace: Cycle	1.4	1.7	5.1	1.0	1.7	1.4	0.4	0.7	2.3	1.3	1.4	-1.5	0.3	0.8	1.3
Average weekly spirits intake	1.3	1.7	7.6	-0.8	-0.7	-0.7	-1.0	-2.8	-0.2	1.0	-0.4	-1.8	-1.1	-1.5	-1.3
Impedance of arm (left)	1.3	6.2	12.8	2.2	1.3	2.1	2.5	3.3	0.7	-1.8	1.4	3.3	3.4	3.6	2.4
Medication: Paracetamol	1.3	2.2	8.0	1.7	1.5	1.7	-1.1	0.6	2.0	2.8	1.1	0.2	1.6	-0.8	0.6
Leg fat mass (right)	1.3	5.2	10.1	-2.2	-2.9	-2.8	-1.7	-3.2	-2.8	-1.3	-2.1	-1.1	-1.6	-2.2	-2.3
Miserableness	1.3	2.3	5.3	0.8	1.4	1.6	0.4	0.9	2.3	1.6	2.1	0.3	2.2	0.6	1.9
Triglycerides	1.2	1.9	5.5	0.0	1.4	1.1	0.2	0.6	2.3	1.0	2.1	1.4	1.3	1.8	1.2
Waist Hip Ratio (WHR)	1.2	5.5	10.0	2.1	2.2	2.2	2.7	2.2	2.3	2.3	2.8	-0.8	3.2	1.3	3.0
Lung FVC	1.2	6.3	15.0	2.8	3.9	3.3	2.5	1.7	2.5	0.8	3.6	0.8	1.5	2.3	2.3
Supplements: Zinc	1.2	1.3	5.2	0.6	0.2	-0.1	1.7	1.5	-0.5	-2.3	0.9	1.0	1.7	0.2	0.1
Nervous feelings	1.2	2.2	6.6	0.6	1.8	1.2	2.6	1.2	1.4	-0.4	1.8	-0.3	1.9	1.1	1.8
Had other major operations	1.2	1.5	4.6	-1.4	0.9	1.1	2.1	1.7	-0.0	-1.5	0.6	-0.5	1.3	1.0	0.9
Medication: Seretide 50 evohaler	1.2	1.4	3.3	0.8	-1.4	-1.6	-1.2	-1.4	-1.1	-0.5	-0.7	-0.3	-0.9	-1.8	-1.6
Financial situation satisfaction	1.2	1.5	2.9	0.9	1.7	1.2	1.1	1.0	0.9	-0.2	1.7	1.0	1.6	0.8	1.6
Relative age of first facial hair	1.1	2.4	7.3	1.3	1.6	0.7	2.7	2.2	0.7	-0.8	1.9	0.4	1.6	0.6	1.9
Diabetes (mother)	1.1	1.4	3.3	0.5	1.2	1.0	1.8	1.1	1.5	0.2	1.2	-0.1	1.6	1.6	1.2
Qualifications: CSEs or equivalent	1.1	1.5	5.0	-0.9	-1.5	-1.5	-1.9	-2.2	0.2	1.3	-0.4	-0.2	-0.9	-0.7	-0.8
High blood pressure (mother)	1.1	1.5	6.4	-0.5	1.3	1.3	1.0	0.8	-0.2	1.0	1.6	-2.5	1.2	0.2	1.1
Impedance of arm (right)	1.1	5.3	13.2	1.7	1.0	1.8	1.9	2.8	0.2	-1.7	1.4	3.5	3.2	3.6	2.0
Loud music exposure frequency	1.1	1.2	7.9	0.4	-0.6	-0.8	1.7	-0.0	-0.3	-2.8	0.1	1.5	0.5	0.1	-0.2
Comparative height size at age 10	1.1	6.3	15.8	-3.6	-1.8	-2.1	-3.6	-2.8	-2.8	-0.4	-1.9	-0.3	-1.8	-4.0	-2.0
Medication: Paracetamol	1.1	1.7	7.0	1.3	1.3	1.5	-0.9	0.7	1.6	2.6	0.6	0.2	1.7	-0.5	0.5
Illnesses of father: High blood pressure	1.1	1.4	3.4	-0.1	-1.5	-1.1	-1.0	-1.0	-1.8	-0.6	-1.6	-0.9	-1.2	-1.2	-1.0
Cholesterol lowering medication	1.1	1.6	3.8	-0.7	-1.1	-0.4	-0.4	-0.9	-1.7	-1.9	-1.9	-1.5	-1.0	-0.9	-1.4
Bipolar Disorder (2011)	1.0	1.0	4.6	0.7	-0.8	-0.5	0.9	0.4	-0.6	-2.1	-1.2	0.7	-0.9	1.3	-0.4
Pulse wave Arterial Stiffness index	1.0	1.1	3.8	-1.3	-1.4	-1.3	-0.3	-2.0	-0.9	-0.6	-0.4	-0.1	-1.1	0.1	-1.3
Average weekly red wine intake	1.0	1.5	4.5	0.1	1.8	1.3	1.4	2.1	0.9	-0.4	1.5	-0.6	1.2	0.7	1.0
Handedness (chirality/laterality): Left-handed	1.0	1.2	4.1	-0.2	1.2	1.0	0.8	1.3	0.5	-0.2	1.4	0.8	2.0	0.6	1.4
Ever had bowel cancer screening	1.0	1.1	6.8	-0.2	-0.4	-0.3	-0.6	-0.2	-0.6	1.4	-0.6	-2.6	-1.1	-1.1	-1.0
Mineral and other dietary supplements	1.0	1.4	5.6	1.0	-1.3	-1.6	0.6	-1.1	0.5	0.4	-0.7	-0.8	-1.3	-2.4	-0.7
Guilty feelings	1.0	1.5	10.5	-0.2	0.9	0.7	0.6	0.6	-1.0	0.1	1.1	-3.2	1.5	-0.1	1.0
Average weekly beer plus cider intake	1.0	1.4	5.6	-0.6	-1.1	-1.1	-2.4	-1.5	0.3	1.5	-0.9	-0.3	-0.9	-0.9	-1.1
Ever had prostate specific antigen (PSA) test	1.0	1.2	3.4	0.3	-0.7	-0.9	0.5	-1.4	-0.7	0.4	-0.5	-1.8	-1.5	-1.6	-1.1
Arm predicted mass (left)	1.0	5.1	13.0	-3.6	-1.6	-2.3	-2.9	-2.9	-2.5	-0.6	-1.5	-0.9	-1.4	-3.1	-1.5
Alzheimer’s Disease (including proxy)	0.9	1.4	4.9	0.8	-0.6	-0.4	-2.2	-0.4	0.3	1.4	-0.5	-1.7	-1.0	-1.9	-0.8
Ovarian Cancer	0.9	1.2	3.8	-0.5	-1.4	-0.5	-1.7	0.0	-2.0	-0.9	-1.8	0.3	-0.6	0.5	-0.9
HbA1C	0.9	0.9	2.8	-0.2	1.0	0.6	-0.4	0.8	1.4	1.4	1.7	-0.4	1.2	-0.7	0.8
Chronotype (morning person)	0.9	2.1	7.8	-0.9	-0.4	-0.0	0.4	1.4	-2.6	-2.8	-2.4	-0.4	0.1	-0.8	-0.5
Maternal smoking around birth	0.9	1.3	4.1	-1.0	-1.8	-2.0	-1.5	-1.2	-0.7	-0.6	-1.1	0.9	-0.7	0.3	-0.5
Relative age voice broke	0.9	1.4	5.3	2.3	0.3	0.5	2.0	1.7	-0.2	-1.4	0.4	-0.3	1.1	0.8	0.7
Had menopause	0.9	1.1	2.5	-0.6	1.4	1.1	1.6	0.9	0.6	-0.5	1.3	-0.2	1.1	0.7	1.6
Length of working week for main job	0.9	1.0	4.2	-1.0	-0.8	-0.3	-1.1	-1.2	-2.1	0.0	-1.1	-1.1	-0.7	0.3	-0.5
Blood clot in the leg (DVT)	0.9	1.1	2.6	1.3	-1.5	-1.6	-1.2	-1.1	0.5	-0.3	-0.5	0.7	-0.6	-0.9	-1.6
Neck or shoulder pain in last month	0.9	1.2	4.5	-0.4	0.9	0.9	1.0	0.8	2.1	0.9	1.2	-0.5	1.5	1.0	1.1
Whole body fat mass	0.9	3.8	7.0	-2.0	-2.6	-2.4	-1.5	-2.6	-2.4	-1.8	-2.0	-0.3	-0.9	-1.6	-1.9
Arm predicted mass (right)	0.9	4.4	11.2	-3.3	-1.5	-2.0	-2.5	-2.8	-2.0	-0.2	-1.3	-1.1	-1.3	-3.3	-1.3
Mouth/teeth dental problems: Mouth ulcers	0.9	1.4	3.5	0.1	-1.5	-1.3	-0.4	-1.0	-0.1	-0.1	-1.5	0.5	-1.8	-1.9	-1.7
Medication: Gliclazide	0.9	1.0	2.3	1.1	1.1	1.5	1.1	1.4	0.3	-0.4	0.3	1.0	0.9	1.0	0.8
Medication: Bendroflumethiazide	0.9	1.3	3.1	-1.5	-0.7	-0.8	-1.1	-1.2	-0.5	1.3	-1.1	-1.8	-1.4	-0.5	-1.2
Vascular/heart problems diagnosed by doctor	0.9	2.5	6.1	0.8	1.3	1.2	1.2	1.7	1.3	0.0	2.3	1.7	2.5	1.6	1.8
Deep venous thrombosis (DVT) (self-reported)	0.9	1.2	2.8	1.0	-1.4	-1.7	-1.3	-1.4	0.6	0.2	-0.2	0.6	-0.7	-1.1	-1.5
Depression (Nagel 2018)	0.8	1.2	6.0	-2.5	-1.4	-1.0	-0.7	-1.2	-1.3	-1.1	-1.0	-0.2	-0.1	-0.1	-0.2
Schizophrenia vs Biploar Disorder	0.8	1.0	5.4	-2.3	-0.4	-0.5	0.2	-1.0	-1.1	-1.4	-0.1	1.0	0.6	0.9	0.3
HDL Cholesterol	0.8	1.3	4.9	-1.4	-0.7	-0.9	-0.2	-0.3	0.5	0.4	-1.3	-2.2	-0.9	-2.1	-0.5
Sensitivity / hurt feelings	0.8	1.4	3.7	-1.9	-0.9	-1.1	0.6	-0.9	-1.3	-0.8	-1.1	-1.8	-0.4	-1.3	-0.9
Ever used hormone-replacement therapy (HRT)	0.8	1.1	4.3	-2.1	1.1	1.0	1.0	-0.4	0.3	0.7	1.1	-0.2	0.8	1.2	1.2
Trunk fat mass	0.8	3.5	6.5	-1.9	-2.5	-2.2	-1.4	-2.3	-2.4	-2.1	-1.9	0.2	-0.6	-1.5	-1.8
Forced vital capacity (FVC)	0.8	3.1	5.9	1.7	2.4	2.3	1.0	1.7	1.2	0.7	2.3	1.3	2.1	1.2	1.9
Weight	0.8	3.9	8.7	-3.0	-2.1	-2.1	-1.7	-2.5	-2.8	-1.7	-1.7	-0.2	-0.8	-1.9	-1.5
Medication for cholesterol, blood pressure or diabetes	0.8	1.3	3.0	-1.2	1.1	0.8	1.4	0.3	-0.1	-0.5	1.7	0.3	1.7	1.0	1.5
Chronic bronchitis/emphysema (mother)	0.8	0.9	2.8	1.5	0.5	0.1	-0.5	-0.2	1.6	1.7	1.2	0.0	0.5	-0.8	0.7
Arm fat-free mass (right)	0.8	3.9	11.4	-3.4	-1.3	-1.8	-2.4	-2.6	-1.7	-0.0	-1.3	-1.2	-1.2	-3.0	-1.2
Age at first live birth	0.8	1.4	2.5	-0.2	1.1	1.5	0.9	0.9	-1.2	-1.5	0.7	1.3	1.5	1.1	1.6
Pulse wave peak to peak time	0.8	0.9	3.4	1.0	1.3	1.2	0.0	1.9	0.6	0.6	0.3	-0.0	1.1	-0.2	1.3
Eye problems/disorders: Cataract	0.8	0.9	2.1	0.7	1.2	1.3	1.3	0.6	0.5	0.3	0.8	0.7	1.4	0.7	1.1
Pain type(s) experienced in last month: Hip pain	0.8	1.0	2.5	-1.0	-1.5	-0.8	-0.5	-1.0	-1.5	-1.1	-1.6	-0.1	-0.8	-0.2	-0.7
Arm fat-free mass (left)	0.8	4.0	9.3	-3.1	-1.4	-2.0	-2.7	-2.7	-1.9	-0.4	-1.3	-0.9	-1.1	-3.0	-1.4
Myopia	0.8	1.2	3.1	1.7	1.3	1.8	1.5	0.6	0.0	0.4	0.6	0.2	0.7	1.3	0.9
Pack years of smoking	0.8	1.1	3.8	1.9	-1.2	-0.7	-1.5	-1.0	0.6	0.5	-1.4	0.4	-0.6	-0.5	-1.0
Bipolar Disorder (2018)	0.7	1.1	3.1	0.8	-1.4	-1.7	-0.3	-0.4	-0.7	-1.0	-0.9	-1.0	-1.8	-0.6	-0.9
Age at First Birth	0.7	1.0	6.5	-2.5	0.6	0.9	-0.2	1.0	0.2	-0.5	-0.7	-0.5	0.9	0.6	0.7
Neuroticism (2016)	0.7	1.0	2.5	0.3	0.6	0.0	1.2	-0.8	-0.2	1.0	1.6	-1.5	1.0	-1.6	0.8
Type 2 Diabetes (T2D) (2012)	0.7	0.8	5.3	0.3	-0.9	-0.4	0.8	0.2	-1.0	-2.3	-0.6	1.1	0.7	0.1	-0.4
Ulcerative Colitis	0.7	1.0	3.0	0.8	-0.7	-1.1	-0.2	0.3	-0.1	-0.4	-0.9	-1.4	-1.7	-1.7	-1.0
Hand grip strength (left)	0.7	1.9	5.5	-2.3	-1.2	-1.2	-1.1	-1.4	-1.5	-0.0	-1.5	-0.2	-1.4	-1.4	-1.7
Ever had hysterectomy (womb removed)	0.7	0.8	2.2	-0.3	1.1	1.1	0.0	1.4	0.2	0.0	0.3	0.8	1.1	1.0	1.5
Mouth/teeth dental problems	0.7	1.1	3.4	1.2	1.4	0.7	0.3	0.5	-0.6	0.0	1.9	0.3	1.4	0.2	1.7
Hip circumference	0.7	2.9	7.2	-1.7	-1.7	-1.6	-1.5	-2.1	-2.7	-2.0	-1.5	-0.5	-0.7	-1.8	-1.5
Ever highly irritable/argumentative for 2 days	0.7	0.8	3.0	-0.7	-1.0	-0.4	0.1	-1.2	-0.9	-1.7	-0.5	1.2	0.4	1.0	-0.2
Body fat percentage	0.7	2.6	5.9	-1.2	-2.4	-2.0	-0.6	-1.9	-1.9	-2.3	-1.7	-0.0	-0.5	-1.0	-1.6
Medication for pain relief, constipation, heartburn	0.7	1.1	3.9	-2.0	-0.9	-1.2	0.0	-0.8	-1.5	-1.5	-1.0	-0.0	-1.0	0.2	-0.3
Medication: Blood pressure	0.7	1.3	3.5	1.9	-1.0	-0.9	-0.8	-0.5	1.0	1.1	-1.1	-0.3	-1.5	-1.4	-1.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.8	5.7	0.4	0.0	0.4	0.0	0.6	1.1	1.1	-0.6	-2.4	-0.2	-0.4	-0.6
Friendships satisfaction	0.7	0.9	2.1	-1.4	-1.1	-1.3	-0.7	-0.6	-1.3	-0.7	-0.8	-1.3	-0.4	-0.3	-0.7
Medication: Aspirin	0.7	1.0	4.9	1.1	-0.9	-1.0	-0.5	-0.1	-0.5	-0.8	-0.8	-2.2	-0.3	-1.1	-0.5
Average weekly champagne plus white wine intake	0.7	0.9	3.7	-0.4	-0.6	-0.2	1.9	0.1	-1.5	-1.3	-1.2	0.4	-0.5	-0.6	-0.8
Basal cell carcinoma (self-reported)	0.7	0.9	1.7	-1.1	0.8	0.9	1.3	0.9	0.8	-0.3	0.9	0.5	1.0	1.3	1.0
Major Depression (MDD)	0.6	0.7	2.3	1.3	0.5	0.7	1.5	0.8	0.8	-0.2	0.3	1.0	0.8	0.8	0.6
Breast Cancer	0.6	1.4	3.1	0.1	-0.8	-1.2	-1.8	-1.7	1.0	1.5	-0.3	0.8	-1.2	-1.2	-1.3
Body Mass Index (BMI) (2010)	0.6	0.8	3.8	0.1	-0.3	-0.1	-1.4	-1.9	0.1	-0.1	-0.3	-0.6	-1.0	0.3	-1.5
Crohns Disease (2012)	0.6	1.0	2.4	0.0	-1.3	-1.6	-0.3	-1.4	-0.7	-1.2	-0.9	-0.1	-1.3	-0.1	-1.2
Mean Putamen Volume	0.6	0.7	4.2	-0.2	-0.3	-0.6	0.5	0.6	-0.1	-0.8	0.6	2.0	0.7	1.1	0.7
Lupus	0.6	0.9	5.1	-1.0	-0.5	-0.4	-2.3	-0.2	0.1	0.6	-0.8	-1.4	-0.8	-0.4	-0.8
Lung FEV1/FVC ratio	0.6	3.2	12.7	3.6	1.3	1.2	1.8	0.3	1.4	1.7	1.8	-0.0	1.8	-2.4	1.7
Hearing difficulty/problems: Yes	0.6	0.9	3.8	-0.5	-1.0	-0.8	0.0	-0.8	-1.3	-2.0	-0.9	-0.4	0.1	-1.1	-0.8
Medication: Metformin	0.6	0.9	4.3	2.1	-0.2	0.4	1.3	-0.1	0.2	-0.7	0.1	1.9	0.6	-0.1	0.2
Pack years adult smoking proportion	0.6	0.9	3.9	2.0	-0.9	-0.5	-1.4	-0.8	0.8	0.7	-1.0	0.4	-0.0	-0.1	-0.6
Trunk fat percentage	0.6	2.3	5.7	-1.1	-2.2	-1.8	-0.5	-1.6	-1.9	-2.4	-1.6	0.6	-0.2	-0.8	-1.4
Fed-up feelings	0.6	1.1	3.4	-1.2	-1.0	-0.7	-1.6	-1.9	0.5	0.8	0.4	-0.4	0.8	-1.7	-0.4
Hayfever, allergic rhinitis or eczema	0.6	1.3	6.2	-1.4	0.2	-0.6	1.4	0.2	-1.0	-2.5	0.5	0.6	1.4	0.9	1.2
Body mass index (BMI)	0.6	2.5	5.5	-2.0	-1.7	-1.8	-0.7	-2.3	-1.8	-1.0	-1.2	-1.3	-1.2	-1.6	-1.5
Heart attack	0.6	0.7	4.1	0.1	0.2	0.2	0.6	-0.1	0.3	1.4	-0.4	-2.0	-0.5	-1.3	-0.2
Pain all over the body in last month	0.6	0.6	1.1	1.0	0.8	1.0	0.3	0.7	0.8	0.7	0.9	0.7	0.5	0.9	0.7
Medication: Simvastatin	0.6	0.9	3.5	1.0	-0.6	-0.1	-0.7	-0.5	-0.4	-0.1	-1.9	-0.5	-1.5	-0.7	-1.3
Pulse rate	0.6	1.0	2.4	-0.8	0.7	0.4	1.6	-0.7	-1.1	-0.4	1.5	1.3	0.9	1.1	1.1
Happiness	0.6	0.7	1.8	-0.6	0.7	0.1	1.3	0.7	-0.5	-0.7	1.2	0.3	1.1	0.0	1.3
Arm fat mass (right)	0.6	2.4	5.7	-2.2	-1.7	-1.7	-0.9	-1.9	-2.4	-1.6	-1.2	-0.5	-0.3	-1.3	-1.3
Trunk predicted mass	0.6	3.2	10.0	-3.2	-0.9	-1.4	-2.6	-2.5	-1.9	-0.1	-0.8	-0.3	-0.8	-2.6	-0.9
Mouth/teeth dental problems: Bleeding gums	0.6	0.7	2.2	-0.4	0.1	0.3	0.9	0.9	1.5	-0.1	0.4	1.4	1.4	0.8	0.2
Birth weight	0.6	1.3	9.3	-0.4	0.5	-0.0	0.4	0.1	0.7	-0.9	1.3	3.0	1.2	0.7	1.2
Had major operations	0.6	0.7	1.6	0.4	0.8	1.1	-0.8	1.3	1.1	1.2	0.3	-0.8	0.7	0.3	0.5
Age at last live birth	0.6	0.8	1.9	-1.3	0.2	0.6	-0.1	0.3	-1.2	-1.1	-0.3	1.2	0.9	1.4	0.7
Family relationship satisfaction	0.6	0.8	2.4	-0.6	-1.0	-1.6	-0.8	-1.2	-1.3	-1.2	-0.4	-0.0	-0.2	-0.2	-0.5
Hypertension (Self-reported)	0.6	1.7	4.1	-0.8	-1.0	-0.9	-1.0	-1.5	-1.1	-0.2	-1.8	-0.7	-2.0	-1.5	-1.7
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.7	4.0	0.1	-0.7	-0.5	0.6	0.4	-1.4	-2.0	-0.7	0.1	-0.2	0.5	-0.3
Breast cancer (self-reported)	0.6	0.8	2.9	1.1	0.8	0.7	1.1	0.7	1.7	0.6	0.8	-0.4	0.7	0.6	0.3
Arm fat mass (left)	0.6	2.6	4.8	-2.1	-1.9	-1.9	-1.0	-2.0	-2.2	-1.7	-1.5	-0.6	-0.5	-1.5	-1.4
Hearing aid user	0.6	0.7	2.1	1.1	-1.5	-1.4	-0.4	-1.1	-0.1	-0.7	-0.4	-0.1	-0.5	-0.4	-0.6
Eye problems/disorders: Glaucoma	0.6	0.7	2.2	-0.0	-1.1	-0.9	-1.4	-0.8	-1.5	-0.4	-1.0	0.4	-0.6	0.3	-0.4
Medication: Blood pressure	0.6	1.1	2.9	-1.3	-0.7	-0.2	-1.2	-1.0	-1.7	-0.6	-1.6	-1.4	-0.6	0.1	-0.8
Heart attack/myocardial infarction (self-reported)	0.6	0.8	5.2	0.3	0.4	0.4	0.9	0.1	0.3	1.5	-0.3	-2.3	-0.3	-1.0	0.0
Heart disease (siblings)	0.6	0.7	3.4	0.3	0.3	-0.1	0.4	-0.9	1.1	0.8	0.4	-1.2	-0.5	-1.9	0.1
Impedance of whole body	0.6	3.0	7.2	2.4	-0.1	0.7	1.5	2.3	0.4	-1.9	0.3	2.7	2.3	2.1	1.3
Blood Eosinophil Count	0.5	3.5	7.7	-0.5	-1.8	-1.9	-2.8	-1.1	-2.3	-0.3	-1.6	-2.4	-0.9	-2.6	-2.2
Allergy or Eczema	0.5	1.3	8.2	-1.2	-0.5	-0.8	1.2	0.0	-1.4	-2.9	-0.7	0.3	0.4	0.2	0.4
Hair Pigment	0.5	13.2	30.6	0.5	5.5	5.4	1.9	3.7	3.3	4.1	3.4	-1.2	3.0	3.8	4.0
Frequency of depressed mood in last 2 weeks	0.5	0.7	2.5	-0.9	-0.5	-0.6	-0.7	-0.2	-0.7	-1.1	0.5	-0.6	1.6	-0.2	1.2
Other serious medical condition/disability diagnosed by doctor	0.5	0.7	2.1	1.4	0.5	1.0	1.5	0.2	0.6	-0.5	0.6	0.8	0.8	0.8	0.5
Medication for hormone replacement therapy	0.5	0.6	1.3	-0.2	0.9	0.8	0.3	0.4	0.7	1.0	1.1	0.2	0.9	0.8	0.9
High blood pressure	0.5	1.5	3.9	-0.8	-1.1	-0.8	-0.7	-1.5	-1.0	-0.3	-1.8	-1.1	-2.0	-1.3	-1.5
Hearing difficulty/problems with background noise	0.5	0.8	3.1	1.6	-0.4	-0.1	1.7	-0.1	-0.0	-1.8	0.3	-0.4	0.9	0.4	0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.1	3.9	-0.8	-1.1	-1.4	-2.0	-0.9	-0.8	0.8	-0.8	-1.1	-0.6	-0.7	-0.9
Allergy	0.5	1.1	8.5	-0.8	0.5	0.8	-1.3	0.2	0.7	2.9	0.2	-0.9	-0.7	-0.6	0.2
Neuroticism score	0.5	1.0	3.0	-0.3	1.1	0.9	1.2	0.4	0.8	0.1	1.4	-0.9	1.7	-0.1	1.2
Trunk fat-free mass	0.5	3.2	10.2	-3.2	-0.8	-1.3	-2.6	-2.4	-1.9	-0.0	-0.9	-0.3	-0.8	-2.5	-0.9
Falls in the last year	0.5	0.6	1.4	0.5	0.2	0.1	0.1	-0.7	0.8	-0.5	1.1	1.2	1.0	1.2	0.9
Hair/balding pattern: Pattern 3	0.5	0.8	2.2	0.5	1.4	1.3	1.5	1.0	0.3	-0.3	0.4	0.6	0.0	1.1	0.8
Number of full brothers	0.5	0.6	2.1	-1.4	-0.2	-0.1	0.7	-0.5	-1.3	-1.1	-0.2	0.2	0.6	0.8	0.5
Pulse rate, automated reading	0.5	1.5	5.7	-1.1	-1.5	-1.7	-1.0	-2.4	-0.8	-0.8	-0.1	1.7	-0.3	0.7	-0.6
Alcohol intake frequency.	0.5	1.2	3.5	0.4	-1.1	-1.0	-1.5	-1.1	-0.8	-1.1	-1.4	1.9	-0.2	-0.5	-0.5
Number of full sisters	0.5	0.6	1.6	0.3	1.0	0.6	0.8	0.1	1.3	0.7	1.1	-0.0	0.5	1.0	0.6
Suffer from ‘nerves’	0.5	0.8	4.2	1.2	0.4	0.4	1.1	0.2	-0.1	-1.0	0.4	2.0	1.0	-0.3	0.2
Whole body fat-free mass	0.5	2.7	10.9	-3.3	-0.8	-1.2	-2.2	-2.1	-1.9	-0.1	-0.8	-0.4	-0.6	-2.2	-0.8
Mood swings	0.5	0.8	2.0	-1.1	0.6	0.3	0.4	-0.3	1.3	0.9	1.4	-0.9	1.1	-1.0	0.7
Loneliness, isolation	0.5	0.7	2.8	-0.7	-1.5	-0.5	-0.7	-0.4	-0.6	-0.7	-1.7	-0.3	0.2	-0.5	-0.5
Osteoporosis (self-reported)	0.5	0.7	2.5	1.1	-0.8	0.0	1.1	-0.1	0.5	-1.6	-0.2	1.2	0.7	0.4	-0.1
Whole body water mass	0.5	2.9	11.4	-3.4	-0.8	-1.3	-2.3	-2.2	-1.9	-0.1	-0.8	-0.4	-0.6	-2.3	-0.9
Medication: Lisinopril	0.5	0.6	2.7	0.5	-0.8	-0.3	-0.4	-0.2	-0.7	-0.0	-1.6	-0.9	-1.0	0.0	-0.9
Basal metabolic rate	0.5	2.9	10.4	-3.2	-1.1	-1.5	-2.1	-2.3	-2.2	-0.6	-1.0	-0.1	-0.5	-2.1	-0.9
Irritability	0.5	0.9	2.6	0.8	-1.1	-1.5	-0.5	-1.5	0.9	0.4	0.3	0.1	-0.5	-1.6	-0.6
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	1.4	1.0	1.0	1.2	1.1	1.2	1.1	-0.2	0.2	0.3	0.4	0.5	0.1
Alcohol drinker status: Previous	0.5	0.5	2.1	0.4	-0.8	-1.1	-0.4	0.3	-0.1	-0.9	-1.4	0.9	-0.1	0.1	-0.8
Crohns Disease (2017)	0.4	0.9	1.7	-1.1	-0.9	-1.3	-1.1	-1.0	-1.0	-1.0	-1.0	-0.4	-1.2	0.4	-0.9
Prostate Cancer	0.4	0.6	4.0	0.6	0.2	-0.1	0.2	-0.3	1.4	2.0	0.9	0.4	0.2	0.2	0.5
Fasting Glucose	0.4	0.5	2.2	-1.2	0.6	0.1	-0.3	-0.7	0.4	0.2	0.8	-1.5	-0.5	-0.6	-0.3
Eye problems/disorders: Diabetes related eye disease	0.4	0.4	1.3	0.1	-0.7	-0.9	0.5	-0.1	-0.4	-1.1	-0.0	0.4	-0.4	-1.1	-0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.5	1.7	-1.3	-0.1	0.7	-1.1	0.4	0.1	0.5	-0.2	-0.6	0.7	0.9	0.6
Sitting height	0.4	3.0	10.8	-3.3	-1.2	-1.2	-2.6	-2.2	-2.3	0.2	-1.2	-1.3	-0.6	-1.4	-0.7
Chronic bronchitis/emphysema (father)	0.4	0.5	2.0	-1.4	-0.5	-0.2	0.4	-1.2	-0.7	-0.6	-0.3	-1.1	-0.2	-0.3	-0.0
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	2.3	-0.7	-0.2	-0.3	0.5	1.1	-0.1	-1.2	-0.7	-1.5	-0.1	0.3	0.2
Medication: Ramipril	0.4	0.5	1.9	1.4	0.4	0.5	0.4	0.2	1.1	0.7	0.9	-0.4	0.6	0.4	-0.1
Alcohol intake versus 10 years previously	0.4	0.5	1.6	-0.2	-0.6	-0.1	-1.0	-1.1	0.7	1.3	-0.5	0.4	-0.5	0.2	-1.1
Worrier / anxious feelings	0.4	0.8	3.9	-0.8	1.1	0.7	0.4	-0.0	0.4	0.7	1.0	-2.0	0.7	-0.8	0.6
Breastfed as a baby	0.4	0.5	3.1	-0.8	-0.0	0.1	-0.0	0.2	0.1	0.5	-0.5	-1.8	-1.1	0.2	-0.7
Headache pain in last month	0.4	0.6	1.5	0.9	0.7	0.5	1.1	0.8	1.2	0.5	0.6	0.3	0.7	1.0	0.8
Glaucoma (self-reported)	0.4	0.5	2.1	1.0	-0.9	-0.9	-0.4	-0.6	-1.5	-0.1	-0.5	0.2	-0.3	-0.1	-0.1
Gout (self-reported)	0.4	0.5	1.7	0.2	-0.1	-0.1	-0.3	-1.0	0.5	1.3	0.1	1.0	-0.8	-0.6	-0.9
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.6	2.0	0.0	0.4	0.5	0.6	1.4	-0.1	-1.4	0.1	0.6	1.1	0.7	0.5
Shortness of breath walking on level ground	0.4	0.5	1.5	-0.2	0.0	-0.4	1.0	-0.6	-0.1	-1.2	-0.1	1.1	-0.5	-0.1	-0.9
Eye problems/disorders: None of the above	0.4	0.5	1.9	0.4	0.8	0.6	-0.3	1.4	0.9	0.6	0.4	-0.9	0.4	-0.0	0.2
Mean time to correctly identify matches	0.4	0.8	2.5	0.7	-0.7	-0.9	0.0	-0.0	-0.8	-1.5	-1.6	-0.5	-1.1	-0.2	-1.0
Long-standing illness, disability or infirmity	0.4	0.6	1.7	1.1	0.4	0.8	1.0	-0.2	1.3	0.7	0.8	-0.7	0.5	0.3	-0.1
Osteoarthritis (self-reported)	0.4	0.6	2.1	-0.9	0.4	0.4	1.2	1.5	0.9	-0.8	0.1	0.2	0.8	0.1	0.2
High cholesterol (Self-reported)	0.4	0.6	4.0	2.0	0.5	0.6	0.3	0.8	0.6	-1.1	-0.2	0.5	0.4	-0.5	-0.1
Depressed Affect (Nagel 2018)	0.3	0.7	2.0	-1.4	-0.3	0.1	-0.5	-1.1	0.9	0.9	0.3	0.0	1.1	-1.4	0.2
Worry (Nagel 2018)	0.3	0.5	1.4	-0.5	0.6	0.4	1.2	0.1	0.4	-1.1	0.5	0.9	1.0	-0.6	0.6
Irritable Bowel Disease (IBD)	0.3	0.6	2.0	-0.8	-0.6	-1.0	-0.5	-0.0	-0.9	-0.9	-1.0	-0.7	-1.4	-0.1	-0.6
Ulcerative Colitis (UC)	0.3	0.5	2.2	-0.6	-0.2	-0.4	0.3	0.3	-0.8	-0.5	-0.9	-1.0	-1.5	-0.8	-0.5
LDL Cholesterol	0.3	0.4	1.0	-0.3	0.7	1.0	0.5	0.5	0.9	0.1	0.7	0.1	0.9	0.9	0.6
BMI	0.3	1.7	5.5	-2.4	-0.6	-0.7	0.4	-1.8	-2.1	-1.7	-0.6	-0.6	-0.0	-1.1	-0.8
Severe depression (siblings)	0.3	0.4	2.3	0.1	0.1	-0.1	0.5	-0.1	-1.2	0.1	0.7	-1.5	0.1	0.2	-0.1
Leg fat-free mass (left)	0.3	1.7	9.6	-3.1	-0.5	-0.8	-1.4	-1.5	-1.8	-0.3	-0.4	0.1	0.0	-1.0	-0.5
Townsend deprivation index at recruitment	0.3	0.5	1.4	1.2	-0.3	-0.4	-1.0	-0.7	0.4	0.5	0.3	0.7	0.7	0.9	-0.0
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.8	4.0	-1.0	-0.8	-0.9	-2.0	-0.5	-0.1	0.6	-0.8	-0.2	-0.6	0.3	-0.9
Supplements: Glucosamine	0.3	0.4	1.5	-0.8	0.6	0.9	-0.2	0.6	-0.8	-0.3	-0.0	0.4	0.4	1.2	-0.0
Medication: Atenolol	0.3	0.4	1.4	1.2	0.2	-0.1	-0.2	0.4	1.1	-0.4	-0.6	0.0	-0.6	-0.3	-0.3
Impedance of leg (left)	0.3	1.4	4.2	2.0	-1.9	-1.4	-0.5	-0.1	-0.3	-1.4	-1.2	1.6	-0.0	-0.3	-0.4
Leg predicted mass (left)	0.3	1.8	9.7	-3.1	-0.6	-0.9	-1.5	-1.6	-1.9	-0.3	-0.5	-0.0	-0.1	-1.2	-0.6
Waist circumference	0.3	0.9	2.3	-1.3	-1.0	-1.0	-0.5	-1.1	-1.5	-0.6	-0.5	-1.3	0.2	-1.2	-0.5
Arm fat percentage (right)	0.3	1.2	4.0	-1.3	-1.3	-1.1	-0.1	-1.0	-1.8	-2.0	-0.8	-0.2	0.2	-0.3	-0.9
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.4	1.6	1.2	0.1	0.1	-0.1	-0.8	0.7	0.9	0.4	-0.4	-0.3	0.6	-0.2
Medication: Cholesterol lowering	0.3	0.4	1.1	1.1	-0.2	-0.2	-0.7	0.1	0.2	0.5	-1.0	-0.4	-1.0	-0.7	-0.7
Medication: Ventolin 100micrograms inhaler	0.3	0.4	1.2	0.0	0.1	-0.5	-0.3	-0.7	0.9	0.4	0.9	-0.8	0.1	-1.1	0.2
Wheeze or whistling in the chest in last year	0.3	0.5	1.6	1.0	-0.3	-0.6	-1.0	-0.3	0.7	0.4	0.2	-1.3	-0.4	-0.5	-0.5
Health satisfaction	0.3	0.4	1.6	0.1	-0.4	-0.4	0.7	-0.1	-0.4	-1.3	-0.0	0.8	0.2	-1.2	-0.6
Emphysema/chronic bronchitis	0.3	0.3	1.1	1.0	0.5	0.9	0.2	0.7	0.4	0.1	-0.2	0.2	0.1	0.9	-0.1
Medication: Ibuprofen	0.3	0.3	1.1	0.3	0.6	0.8	0.8	-0.4	0.6	0.5	0.3	-0.3	0.0	1.1	0.1
Medication: Omeprazole	0.3	0.4	1.0	0.8	1.0	1.0	0.6	0.8	0.7	0.0	0.2	-0.0	0.4	-0.2	0.2
Heart disease (mother)	0.3	0.3	1.2	0.1	1.1	0.8	0.3	-0.4	0.6	0.8	0.8	-0.3	0.5	0.3	0.4
Leg pain on walking	0.3	0.4	1.9	-0.6	-0.3	0.0	-0.4	-1.4	-0.3	0.1	-0.3	0.6	-0.8	-0.5	-0.5
Medication: Aspirin	0.3	0.4	2.1	0.8	-0.5	-0.7	-0.4	-0.0	-0.2	-0.7	-0.1	-1.5	0.1	-0.7	-0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.3	1.4	0.3	0.1	0.4	0.5	1.1	-0.0	-1.2	-0.6	0.1	0.2	-0.6	-0.5
Illnesses of father: Heart disease	0.3	0.4	1.1	-0.5	0.1	0.1	0.0	-0.6	-0.8	-1.0	-0.6	-0.8	-1.1	-0.7	-0.3
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.6	1.8	-0.8	-0.9	-0.7	-1.2	-0.6	-1.3	0.3	-0.3	0.6	0.6	-0.2	-0.5
Leg fat-free mass (right)	0.3	1.5	9.2	-3.0	-0.4	-0.7	-1.4	-1.3	-1.5	-0.1	-0.5	0.0	0.0	-1.1	-0.4
Qualifications: nursing, teaching	0.3	0.5	2.8	0.0	0.1	-0.4	1.7	-0.6	0.1	-0.9	1.0	0.6	-0.4	0.1	0.1
Asthma (self-reported)	0.3	0.5	1.4	1.0	-0.4	-0.4	0.1	-0.7	-0.5	-0.1	-0.8	-1.1	-0.9	-0.5	-1.2
Leg predicted mass (right)	0.3	1.5	9.6	-3.1	-0.3	-0.7	-1.4	-1.3	-1.5	0.0	-0.4	-0.0	0.1	-1.2	-0.4
Ever taken oral contraceptive pill	0.3	0.3	1.0	0.3	0.1	0.5	-0.6	0.9	0.6	0.3	-0.6	0.3	0.3	1.0	-0.0
Number of operations (self-reported)	0.3	0.5	2.2	0.1	0.6	0.8	-0.4	0.7	1.0	0.7	0.2	-1.5	0.5	-0.0	0.1
Fractured/broken bones in last 5 years	0.3	0.4	0.9	0.7	-0.6	-0.8	-0.3	-0.7	0.9	-0.6	-0.1	0.0	-0.4	-0.9	-0.7
Age started oral contraceptive pill	0.3	0.4	1.4	1.2	0.1	0.2	1.2	-0.3	0.7	0.0	-0.0	-0.4	-0.8	-0.2	-0.3
Ever depressed for a whole week	0.3	0.4	1.9	-0.1	0.1	-0.0	0.5	1.1	0.2	-1.4	-0.8	-0.6	0.4	0.1	-0.0
Unable to work because of sickness or disability	0.3	0.4	1.9	-0.7	-0.6	-0.3	-0.8	-1.4	-0.3	0.5	-0.4	0.3	-0.9	-0.1	-0.7
Pain experienced in last month	0.3	0.5	1.8	0.7	-0.4	-0.2	-1.3	-0.5	-1.2	-0.2	-0.4	-0.2	-1.0	-0.3	-0.4
Neuroticism (Nagel 2018)	0.2	0.5	2.3	-0.7	-0.0	0.2	0.9	-0.8	0.3	-0.5	0.3	-0.2	1.1	-1.5	0.2
Alzheimer’s Disease (in mother)	0.2	0.2	1.2	-0.0	-0.1	-0.1	-1.1	0.5	-0.5	-0.4	0.0	-0.6	0.2	-0.7	0.2
Alzheimer’s Disease (in father)	0.2	0.2	0.5	0.3	-0.5	0.1	-0.3	-0.2	-0.6	0.6	-0.4	-0.7	-0.2	0.2	0.0
Reaction Time	0.2	0.4	1.6	0.8	-0.2	-0.5	-0.3	0.5	-1.0	-1.3	-0.9	0.0	-0.3	0.6	-0.3
Coronary Artery Disease (CAD)	0.2	0.3	0.8	0.1	-0.9	-0.5	-0.1	0.1	-0.1	-0.6	-0.5	0.6	0.9	-0.1	0.4
Primary Biliary Cirrhosis	0.2	0.3	2.0	0.1	-0.0	-0.1	-1.4	-0.0	-1.0	-0.6	-0.3	0.5	-0.2	0.3	-0.3
Heel T-Score	0.2	1.3	7.5	-0.9	0.7	0.5	-1.8	0.1	0.2	1.6	-0.4	-2.7	-0.4	-0.3	-0.4
Height	0.2	3.6	9.0	-3.0	-1.6	-0.8	-2.9	-0.4	-2.6	-1.6	-2.0	2.1	1.6	-1.6	0.0
Cardiovascular Disease	0.2	0.6	1.1	0.1	-0.2	0.0	-0.8	-1.0	-1.0	-0.1	-1.0	-0.8	-0.9	-0.7	-1.0
Hypothyroidism (self reported)	0.2	0.4	2.4	-1.5	-0.5	-0.2	-0.7	0.0	0.5	-0.5	-0.2	0.7	0.6	0.1	-0.0
Respiratory disease	0.2	0.3	1.1	1.0	0.5	0.6	0.2	0.7	-0.3	0.2	-0.3	-1.0	0.2	-0.4	-0.7
Neuroticism	0.2	0.5	1.2	-0.9	0.3	-0.2	1.0	0.2	-0.1	-0.7	0.7	-0.5	1.1	-1.0	0.5
Number of treatments/medications taken	0.2	0.4	1.0	-0.8	0.2	0.5	-0.7	-0.4	0.5	1.0	-0.6	-0.9	-0.2	-0.6	-1.0
Impedance of leg (right)	0.2	1.1	3.7	1.9	-1.6	-1.0	-0.1	0.0	-0.5	-1.5	-0.8	1.5	0.3	0.3	-0.1
Hand grip strength (right)	0.2	0.5	2.7	-1.6	-0.4	-0.2	-0.0	-0.5	-0.7	-0.1	-0.5	1.6	-0.2	0.1	-0.2
Taking other prescription medications	0.2	0.4	1.8	0.5	-0.1	-0.1	0.1	-0.2	0.9	0.6	0.0	-1.0	-0.2	-1.3	-0.6
Asthma	0.2	0.4	2.2	1.5	0.1	-0.1	0.5	-0.3	0.0	0.2	0.0	-0.9	-0.4	-0.3	-0.7
Standing height	0.2	2.2	5.4	-2.3	-0.8	-0.7	-2.3	-0.6	-2.1	-1.5	-0.8	2.2	1.1	-0.7	0.3
Tense / ‘highly strung’	0.2	0.3	0.9	0.5	0.5	-0.1	0.2	0.3	0.9	-0.4	0.9	-0.0	0.3	-0.6	0.6
Birth weight of first child	0.2	0.4	1.6	-0.2	0.3	0.1	-1.3	0.2	-0.7	0.2	0.9	0.3	1.0	0.0	0.9
Exposure to tobacco smoke outside home	0.2	0.3	1.7	0.1	-0.1	0.1	0.0	-0.0	0.1	-0.5	0.2	1.3	1.0	0.7	0.2
Mouth/teeth dental problems: Loose teeth	0.2	0.2	0.9	0.4	-0.8	-0.4	0.4	-0.5	-0.1	-0.9	-0.0	-0.4	0.2	0.5	-0.2
Medication: Allopurinol	0.2	0.2	0.9	-0.0	-0.0	0.0	0.3	-0.7	0.4	0.3	-0.2	0.4	-0.8	-0.4	-0.9
Overall health rating	0.2	0.4	2.1	0.6	0.3	0.7	0.3	0.2	0.1	-0.1	0.6	0.4	1.4	0.9	0.6
Arm fat percentage (left)	0.2	0.9	3.2	-1.1	-1.2	-0.9	0.2	-0.8	-1.5	-1.8	-0.8	-0.3	0.3	-0.2	-0.7
Diabetes diagnosed by doctor	0.2	0.3	1.0	0.4	-0.9	-0.3	0.1	-0.0	-0.4	-1.0	-0.8	0.6	-0.1	-0.4	-0.2
Medication for cholesterol	0.2	0.3	0.6	0.3	0.1	-0.3	0.6	0.8	0.6	0.2	0.6	0.7	0.2	-0.6	0.4
Number of self-reported non-cancer illnesses	0.2	0.4	1.6	0.5	0.9	0.8	0.9	0.4	0.4	0.2	0.6	-1.2	0.1	-0.1	-0.2
Blood Platelet Count	0.1	0.8	3.2	-1.1	-0.3	0.4	-1.3	0.4	-1.8	-0.3	-1.2	-0.7	-0.6	0.0	-0.5
Blood White Count	0.1	0.5	1.4	0.5	-0.6	-0.5	-1.1	-0.8	-1.2	-1.0	0.0	-0.7	0.8	-0.3	-0.4
Systolic Blood Pressure	0.1	0.4	1.3	0.7	0.1	0.5	0.4	0.8	-0.2	1.0	0.4	-0.5	0.2	1.1	0.5
Type 2 Diabetes (T2D) (2018)	0.1	0.2	0.8	0.8	-0.4	0.2	0.6	-0.0	-0.4	-0.9	-0.4	0.6	0.2	0.0	-0.1
Systolic blood pressure, automated reading	0.1	0.2	0.7	-0.7	0.0	0.2	0.8	-0.1	-0.3	0.3	0.3	-0.7	-0.2	0.3	0.3
Medication: Levothyroxine sodium	0.1	0.2	0.6	-0.4	-0.7	-0.5	-0.6	-0.0	0.4	-0.7	-0.3	0.5	0.1	-0.4	-0.3
Diabetes (self-reported)	0.1	0.2	0.5	-0.2	-0.7	-0.1	-0.3	-0.7	-0.6	-0.4	-0.7	0.6	-0.0	0.2	-0.2
Exposure to tobacco smoke at home	0.1	0.2	0.5	0.0	-0.5	-0.5	-0.0	0.2	-0.4	-0.7	-0.5	-0.6	-0.1	0.3	0.0
Hypothyroidism/myxoedema (self-reported)	0.1	0.3	0.8	-0.9	-0.9	-0.6	-0.3	-0.4	-0.1	-0.8	-0.6	0.4	0.1	-0.2	-0.2
Medication: Atorvastatin	0.1	0.1	0.3	0.6	0.4	0.3	0.4	0.2	0.4	-0.4	0.3	0.2	0.5	-0.3	0.2
Risk taking	0.1	0.1	0.4	0.3	-0.3	-0.6	-0.0	-0.0	-0.4	-0.2	0.4	-0.4	0.5	0.2	0.2

Hub : Genes

EFTUD1

Models

Trait associations