Hub : Genes

ENOSF1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Adipose Subcutaneous 0.1020 0.0360 2.3e-03 0.032 NA 0.017 NA 0.029 1.1e-03 NA 1.5e-02 NA 1.7e-03
2 GTEx Adipose Visceral Omentum 0.1670 0.0520 1.8e-04 0.070 NA 0.081 NA 0.095 1.7e-04 NA 5.6e-05 NA 1.2e-05
3 GTEx Adrenal Gland 0.4313 0.0748 1.7e-10 0.277 NA 0.328 NA 0.390 1.8e-10 NA 1.9e-12 NA 4.5e-15
4 GTEx Brain Nucleus accumbens basal ganglia 0.3160 0.1220 6.2e-03 0.010 NA 0.045 NA 0.162 1.7e-01 NA 2.4e-02 NA 4.2e-05
5 GTEx Breast Mammary Tissue 0.2080 0.0670 1.0e-03 0.042 NA 0.052 NA 0.074 3.1e-03 NA 1.1e-03 NA 1.2e-04
6 GTEx Breast Mammary Tissue (Male) 0.0988 0.1316 2.9e-01 0.004 NA -0.001 NA -0.006 2.6e-01 NA 3.3e-01 NA 4.7e-01
7 GTEx Breast Mammary Tissue (Female) 0.1558 0.0976 9.0e-02 0.042 NA -0.004 NA 0.067 2.1e-02 NA 4.6e-01 NA 4.9e-03
8 GTEx Cells Transformed fibroblasts 0.3430 0.0560 1.4e-15 0.140 NA 0.285 NA 0.279 1.2e-10 NA 1.4e-21 NA 4.2e-21
9 GTEx Colon Transverse 0.3750 0.0670 4.6e-12 0.267 NA 0.312 NA 0.358 4.5e-13 NA 2.1e-15 NA 6.7e-18
10 GTEx Esophagus Gastroesophageal Junction 0.2550 0.0830 6.0e-04 0.132 NA 0.105 NA 0.114 1.7e-05 NA 1.3e-04 NA 6.4e-05
11 GTEx Esophagus Mucosa 0.4050 0.0570 0.0e+00 0.340 NA 0.459 NA 0.416 1.7e-23 NA 8.8e-34 NA 7.1e-30
12 GTEx Esophagus Muscularis 0.2150 0.0490 8.4e-08 0.142 NA 0.152 NA 0.179 5.8e-09 NA 1.6e-09 NA 4.5e-11
13 GTEx Lung 0.1565 0.0462 5.8e-05 0.051 NA 0.074 NA 0.059 8.5e-05 NA 2.5e-06 NA 2.7e-05
14 GTEx Muscle Skeletal 0.1927 0.0385 1.2e-13 0.096 NA 0.154 NA 0.157 1.1e-09 NA 6.4e-15 NA 3.6e-15
15 GTEx Nerve Tibial 0.1460 0.0466 1.1e-03 0.084 NA 0.096 NA 0.093 1.6e-06 NA 2.5e-07 NA 4.0e-07
16 GTEx Pancreas 0.2940 0.0650 1.5e-07 0.293 NA 0.239 NA 0.241 7.5e-13 NA 1.8e-10 NA 1.5e-10
17 GTEx Pituitary 0.4680 0.1320 6.4e-04 0.195 NA 0.117 NA 0.139 1.3e-05 NA 7.5e-04 NA 2.4e-04
18 GTEx Skin Sun Exposed Lower leg 0.2240 0.0540 7.8e-06 0.017 NA 0.042 NA 0.033 1.4e-02 NA 2.1e-04 NA 8.8e-04
19 GTEx Stomach 0.2920 0.0660 7.4e-07 0.094 NA 0.116 NA 0.104 3.0e-05 NA 3.5e-06 NA 1.2e-05
20 GTEx Testis 0.4030 0.0670 5.3e-11 0.341 NA 0.328 NA 0.344 7.5e-16 NA 3.5e-15 NA 5.3e-16
21 METSIM Adipose 0.1076 0.0242 1.5e-09 0.084 0.075 0.098 0.094 0.089 1.4e-12 2.7e-11 1.6e-14 5.8e-14 3.1e-13
22 NTR Blood 0.0675 0.0138 2.1e-15 0.053 0.058 0.056 0.059 0.057 1.3e-16 3.9e-18 2.1e-17 2.4e-18 7.4e-18
23 YFS Blood 0.4719 0.0325 0.0e+00 0.163 0.380 0.402 0.388 0.391 7.2e-51 2.5e-133 3.9e-143 7.4e-137 2.3e-138
24 TCGA Bladder Urothelial Carcinoma 0.1270 0.0470 5.4e-12 0.110 0.150 0.174 NA 0.174 1.5e-09 1.1e-12 1.2e-14 NA 1.3e-14
25 TCGA Breast Invasive Carcinoma 0.0784 0.0264 5.6e-17 0.055 0.098 0.103 NA 0.105 1.7e-11 2.0e-19 2.4e-20 NA 9.4e-21
26 TCGA Cervical Squamous Cell Carcinoma 0.1170 0.0510 4.8e-05 0.027 0.077 0.051 NA 0.052 1.7e-02 1.2e-04 1.5e-03 NA 1.5e-03
27 TCGA Colon Adenocarcinoma 0.2720 0.0720 1.3e-15 0.204 0.251 0.288 NA 0.285 5.7e-12 9.9e-15 5.7e-17 NA 8.1e-17
28 TCGA Esophageal Carcinoma 0.1810 0.0860 4.2e-04 0.081 0.063 0.050 NA 0.109 1.5e-03 4.6e-03 1.1e-02 NA 2.5e-04
29 TCGA Head and Neck Squamous Cell Carcinoma 0.1243 0.0354 0.0e+00 0.125 0.186 0.196 NA 0.192 7.0e-14 1.7e-20 1.6e-21 NA 4.2e-21
30 TCGA Kidney Renal Clear Cell Carcinoma 0.2887 0.0635 0.0e+00 0.262 0.302 0.308 NA 0.310 2.4e-29 2.1e-34 3.8e-35 NA 2.0e-35
31 TCGA Kidney Renal Papillary Cell Carcinoma 0.2710 0.0810 9.2e-10 0.179 0.145 0.203 NA 0.193 1.8e-10 1.2e-08 7.7e-12 NA 3.0e-11
32 TCGA Brain Lower Grade Glioma 0.0346 0.0207 2.2e-03 0.040 0.016 0.007 NA 0.027 2.1e-05 5.9e-03 5.3e-02 NA 4.0e-04
33 TCGA Liver Hepatocellular Carcinoma 0.1080 0.0740 4.2e-03 0.027 0.001 0.011 NA 0.015 1.9e-02 2.8e-01 9.4e-02 NA 6.5e-02
34 TCGA Lung Adenocarcinoma 0.1345 0.0413 5.6e-17 0.123 0.139 0.135 NA 0.134 3.2e-14 5.4e-16 1.8e-15 NA 2.2e-15
35 TCGA Lung Squamous Cell Carcinoma 0.0831 0.0329 6.8e-09 0.094 0.078 0.075 NA 0.093 8.6e-11 3.5e-09 7.0e-09 NA 1.1e-10
36 TCGA Ovarian Serous Cystadenocarcinoma 0.0720 0.0490 4.9e-03 0.062 0.040 0.035 NA 0.042 5.5e-05 1.0e-03 1.9e-03 NA 7.7e-04
37 TCGA Pancreatic Adenocarcinoma 0.1600 0.0640 4.5e-06 0.099 0.137 0.166 NA 0.154 6.1e-05 2.3e-06 1.8e-07 NA 5.5e-07
38 TCGA Prostate Adenocarcinoma 0.3479 0.0675 0.0e+00 0.243 0.399 0.397 NA 0.389 3.3e-25 1.7e-44 3.8e-44 NA 4.1e-43
39 TCGA Rectum Adenocarcinoma 0.4650 0.1490 2.4e-05 0.098 0.074 0.122 NA 0.072 2.8e-03 8.6e-03 8.8e-04 NA 9.3e-03
40 TCGA Stomach Adenocarcinoma 0.1940 0.0520 0.0e+00 0.245 0.248 0.262 NA 0.262 8.8e-18 6.0e-18 4.9e-19 NA 4.5e-19
41 TCGA Testicular Germ Cell Tumors 0.2280 0.1060 1.3e-05 0.032 0.097 0.050 NA 0.058 2.6e-02 2.6e-04 7.6e-03 NA 4.3e-03
42 TCGA Thyroid Carcinoma 0.3380 0.0810 0.0e+00 0.301 0.303 0.315 NA 0.310 1.2e-29 7.7e-30 3.3e-31 NA 1.1e-30

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42
Bipolar Disorder (2018) 0.7 1.1 3.3 -0.5 0.7 0.7 -1.5 -0.4 -0.9 0.2 0.3 0.8 0.8 0.4 1.5 0.9 -1.4 -1.5 0.1 0.4 -1.2 0.9 0.4 1.7 -0.4 -0.1 1.1 1.4 1.2 1.2 -0.3 1.4 1.5 1.0 -0.3 1.0 1.3 1.5 1.0 1.3 1.0 1.8 1.3 1.1 1.3
Bipolar Disorder or Schizophrenia 0.4 0.9 5.8 -0.8 0.5 0.7 -1.5 -0.7 0.4 -0.2 0.1 0.8 1.1 0.1 1.4 0.9 -0.9 -2.4 0.3 0.2 -0.4 0.8 -0.2 1.0 -0.9 0.2 1.0 0.9 1.5 0.8 0.3 1.1 1.4 1.2 -0.5 0.7 1.2 1.3 0.5 1.2 1.3 1.1 0.4 0.8 1.3
Depressed Affect (Nagel 2018) 0.5 1.1 5.6 -1.3 -0.8 -0.6 -2.1 -2.0 0.6 -1.8 -0.4 -1.0 0.6 -0.9 0.1 -0.3 1.5 0.3 -1.2 -1.4 -1.3 -0.1 -1.4 0.3 1.1 2.4 -0.9 -0.5 -1.3 -0.8 -0.9 -0.8 -0.2 0.5 1.5 -0.2 -0.3 -0.7 -1.3 -0.5 -0.5 0.6 -1.0 -1.0 0.8
Depression (Nagel 2018) 0.3 0.4 3.6 0.3 0.5 0.7 -1.0 -0.3 0.9 0.2 0.9 0.4 0.9 0.4 0.8 1.3 -0.2 0.4 0.6 0.4 0.2 0.8 0.1 1.1 -0.3 1.0 0.2 0.4 -0.5 0.0 0.9 0.3 0.4 0.5 -0.4 0.4 0.6 0.0 -0.2 0.1 0.5 1.9 0.1 0.0 0.9
Intelligence (Savage-Jansen 2018) 0.8 2.4 6.0 -0.8 -1.8 -1.7 -0.5 -0.6 0.6 -0.7 -1.7 -1.4 -2.1 -0.7 -2.1 -1.6 2.0 0.5 -0.6 -0.7 0.6 -1.7 -1.3 -2.4 1.2 -0.5 -1.7 -2.5 -1.5 -2.1 -0.9 -2.0 -1.8 -1.7 0.5 -2.3 -1.7 -1.9 -1.4 -1.3 -1.2 -1.8 -2.1 -1.4 -2.0
Neuroticism (Nagel 2018) 0.2 0.4 1.7 -0.1 -0.6 -0.3 -0.9 -0.5 1.3 -0.6 -0.0 -0.8 -0.1 -0.6 -0.3 0.0 0.9 1.0 -0.2 -0.5 -0.7 -0.4 -0.7 -0.3 0.2 0.5 -0.9 -0.6 -1.2 -0.7 -0.5 -0.8 -0.6 -0.3 0.3 -0.4 -0.6 -1.0 -1.0 -0.8 -0.5 0.4 -0.8 -0.8 -0.0
Schizophrenia (2018) 0.2 0.3 3.7 -0.6 0.1 0.3 -0.8 -0.5 1.1 -0.5 -0.0 0.4 0.8 0.1 0.6 0.3 0.0 -1.9 0.3 -0.1 0.5 0.5 -0.2 0.0 -0.7 0.3 0.4 0.0 0.9 0.0 0.4 0.3 0.6 0.6 -0.4 0.2 0.5 0.4 -0.2 0.5 0.7 -0.1 -0.4 0.3 0.6
Schizophrenia vs Biploar Disorder 1.3 1.7 5.9 -0.5 -1.4 -1.2 0.2 -0.2 0.5 -0.4 -0.2 -1.3 -1.0 -0.3 -1.7 -2.0 1.9 0.9 -0.2 -0.6 -0.2 -1.3 -1.3 -1.8 0.2 -1.0 -1.4 -1.9 -1.3 -1.7 -1.2 -1.6 -1.7 -1.5 0.2 -1.8 -1.5 -1.6 -0.9 -1.3 -1.4 -2.4 -1.9 -1.1 -1.5
Worry (Nagel 2018) 0.7 1.5 3.6 -0.2 -1.3 -1.1 -0.4 -0.1 0.9 -0.6 -0.9 -1.4 -1.6 -1.1 -1.4 -1.0 1.4 1.0 -0.5 -0.9 -0.6 -0.8 -1.0 -1.6 1.0 -0.8 -1.7 -1.6 -1.6 -1.6 -0.7 -1.6 -1.5 -1.3 0.4 -1.2 -1.7 -1.9 -1.8 -1.4 -1.1 -1.1 -1.5 -1.3 -1.4
Alzheimer’s Disease (in mother) 0.9 1.1 5.3 -2.0 0.4 0.5 -2.3 -1.3 1.5 -0.1 0.1 0.8 1.0 -0.1 1.3 -0.1 -0.5 -2.2 -0.4 -0.2 -0.8 0.9 -0.8 0.3 -1.3 0.4 1.0 0.7 1.1 0.7 -0.3 1.1 1.4 0.9 -0.2 0.5 1.1 1.6 -0.4 1.6 1.1 0.8 0.2 0.9 1.6
Alzheimer’s Disease (in father) 2.7 2.9 7.3 1.8 1.8 1.7 0.2 1.7 0.7 1.9 2.0 2.1 1.2 1.6 1.3 2.7 -1.9 -0.6 1.7 1.7 0.6 1.2 2.3 1.2 -1.3 -1.0 1.9 1.7 1.9 2.0 2.0 1.9 1.6 1.3 -1.7 1.4 1.9 1.8 2.4 1.7 1.9 1.2 1.8 2.1 1.3
Alzheimer’s Disease (including proxy) 1.8 2.6 5.8 -0.1 1.3 1.3 -0.9 0.5 2.2 1.2 1.3 2.0 1.3 1.0 1.8 1.5 -1.9 -1.7 0.7 1.1 0.4 1.3 1.2 0.9 -1.7 -0.5 2.0 1.7 2.4 2.0 1.2 2.2 2.1 1.6 -1.1 1.4 2.2 2.4 1.2 2.4 2.1 1.4 1.7 2.1 1.8
Crohns Disease (2017) 0.1 0.2 2.5 0.4 -0.1 -0.1 0.8 0.0 -1.2 -0.2 0.3 -0.1 0.5 0.5 0.2 -0.3 0.2 1.6 -0.2 -0.2 -0.4 -0.7 -0.2 0.4 0.4 0.5 -0.0 0.2 -0.1 -0.2 -0.5 -0.0 -0.1 -0.1 0.3 -0.1 0.0 0.0 0.4 -0.4 -0.4 1.4 0.0 -0.5 0.2
Irritable Bowel Disease (IBD) 0.3 0.7 6.3 0.4 0.4 0.5 0.7 -0.0 -0.3 -0.1 1.0 0.4 1.4 0.7 1.1 0.3 -0.5 0.9 -0.0 0.3 -0.4 -0.9 0.3 1.3 -0.3 1.9 0.7 1.0 0.6 0.7 -0.2 0.7 0.8 0.9 0.0 0.6 0.8 1.0 0.7 0.6 0.4 2.5 0.8 0.2 1.2
Ulcerative Colitis (UC) 0.7 1.3 7.1 0.2 0.9 0.9 0.5 -0.1 0.5 0.1 1.3 0.7 1.8 0.6 1.4 1.0 -0.9 -0.1 0.1 0.5 -0.7 -1.0 0.6 1.9 -0.9 2.5 1.1 1.3 0.9 1.2 0.1 1.1 1.2 1.5 -0.2 0.9 1.1 1.5 0.7 1.2 0.9 2.7 1.1 0.6 1.7
Major Depression (MDD) 0.2 0.2 2.2 -0.1 0.2 0.2 0.0 -0.8 -1.5 -0.4 -0.6 -0.2 0.5 -0.7 0.2 1.5 -0.3 -0.5 -0.3 -0.2 0.4 0.1 0.2 0.5 -0.3 0.1 0.0 0.1 -0.4 -0.1 0.3 0.0 0.0 -0.1 0.1 0.8 0.3 -0.2 0.2 -0.5 -0.5 -1.1 -0.0 0.2 0.2
Reaction Time 0.8 1.6 5.1 1.1 0.8 1.2 0.3 1.4 -0.1 1.5 1.0 1.6 0.0 1.7 0.6 1.4 -1.1 0.6 2.3 1.7 2.2 1.6 1.4 0.7 -1.1 -1.5 1.2 0.8 1.1 1.3 1.2 1.1 0.8 1.0 -2.1 0.8 1.3 1.1 1.8 0.9 1.4 -0.2 0.8 1.7 0.5
Verbal and Numeric Reasoning (VNR) 0.8 1.8 4.9 0.7 -1.2 -1.2 1.1 0.2 0.4 -0.3 -1.2 -1.5 -1.3 -0.7 -1.9 -0.2 1.5 2.2 -0.0 -0.6 0.6 -1.4 -0.6 -2.0 0.9 -0.4 -1.7 -1.9 -1.8 -1.9 -0.6 -1.7 -1.8 -1.9 0.4 -1.5 -1.8 -2.1 -0.6 -1.9 -1.3 -1.2 -1.6 -1.1 -2.0
Breast Cancer 0.1 0.3 1.5 -1.0 0.4 0.5 -0.0 -0.4 1.2 0.3 -0.2 0.1 0.8 0.6 0.6 0.6 0.0 -0.6 -0.2 0.0 1.1 0.4 -0.6 -0.6 -0.7 -0.5 0.1 0.1 0.3 -0.5 0.6 0.2 0.5 -0.1 -0.4 0.8 -0.2 -0.0 -0.6 0.4 -0.1 -0.6 -0.3 0.5 0.0
Ovarian Cancer 0.8 1.1 4.4 0.4 0.9 1.0 0.2 1.4 2.1 1.4 0.5 1.1 0.3 0.8 0.6 0.3 -1.2 -0.7 1.3 1.4 -0.4 1.2 0.6 0.9 -1.3 -1.4 1.1 0.7 1.2 1.0 0.7 1.0 1.1 1.1 -1.4 0.1 0.9 0.9 -0.1 1.8 1.4 1.5 1.0 1.1 0.6
Prostate Cancer 0.9 1.2 5.1 -1.9 -0.7 -0.7 -2.1 -2.1 2.1 -1.9 -0.2 -0.6 -0.1 -1.1 0.2 -1.7 1.0 -1.9 -1.3 -0.8 -0.1 -0.5 -1.0 0.6 0.1 2.3 -0.2 -0.1 -0.0 0.0 -1.1 -0.1 0.4 1.4 1.7 0.1 0.6 0.5 -1.7 0.8 0.4 0.4 -0.0 -0.3 1.0
Age at First Birth 1.6 2.3 4.5 0.7 1.9 1.8 -0.1 0.8 0.6 1.3 1.9 1.9 1.3 1.7 1.8 1.3 -1.5 -0.5 1.4 1.6 0.2 1.4 0.9 1.5 -1.3 -0.5 1.9 1.8 2.1 1.8 1.6 1.9 1.8 1.5 -1.5 1.6 1.8 1.8 1.5 2.0 1.6 1.0 1.7 1.7 1.7
Bipolar Disorder (2011) 0.4 0.4 1.8 -0.4 0.4 0.5 -0.4 -0.0 0.2 0.2 -0.5 0.6 0.1 -0.0 0.9 1.3 -0.6 -1.2 0.3 0.5 0.9 1.2 0.5 0.8 0.4 0.5 0.5 0.7 0.8 0.6 0.0 0.7 0.9 0.7 -0.3 0.8 0.6 0.8 0.4 0.8 0.6 0.2 0.7 0.7 0.7
Body Mass Index (BMI) (2010) 0.1 0.1 0.6 -0.0 0.2 0.3 -0.7 -0.4 -0.3 0.2 0.4 -0.1 0.3 -0.1 0.2 0.1 -0.2 -0.8 0.6 0.0 -0.2 -0.1 -0.2 -0.5 -0.2 0.2 0.1 -0.1 -0.3 -0.2 0.1 0.0 0.1 0.3 -0.5 0.0 0.1 -0.1 -0.4 0.2 0.3 0.1 -0.4 -0.1 0.5
Coronary Artery Disease (CAD) 0.7 0.8 3.6 1.4 -0.0 -0.2 1.3 1.2 0.1 0.7 -1.0 -0.1 -1.5 -0.1 -1.2 -0.0 0.4 1.9 0.6 0.3 0.3 -0.4 0.1 -1.3 -0.0 -1.2 -0.4 -0.9 -0.6 -0.9 1.1 -0.8 -1.0 -1.3 -0.6 -0.7 -1.0 -1.4 0.1 -1.1 -0.5 -0.8 -0.5 -0.6 -1.5
Crohns Disease (2012) 0.3 0.6 2.7 0.5 0.8 0.7 0.5 0.3 -1.4 0.4 0.8 0.6 1.1 1.3 0.8 0.1 -0.8 1.7 0.3 0.3 -0.3 0.3 0.8 0.8 -0.5 0.8 0.7 1.0 0.6 0.7 0.3 0.7 0.7 0.6 -0.3 1.0 0.5 0.6 0.7 0.4 0.6 1.1 0.7 0.4 0.8
Mean Putamen Volume 1.3 1.5 4.7 -0.8 1.1 1.1 -1.5 -0.3 0.5 0.7 1.7 1.0 2.2 1.5 1.7 1.6 -0.9 -0.5 0.6 0.2 -0.5 0.7 0.1 1.2 -2.0 1.1 1.4 1.3 1.3 1.2 1.1 1.4 1.6 1.6 -0.4 1.5 1.3 1.7 0.6 1.7 1.4 0.4 0.6 0.8 2.0
Fasting Glucose 0.3 0.4 2.6 0.6 -0.1 -0.2 1.6 0.4 -1.4 0.6 -0.7 -0.1 -0.5 -0.6 -0.3 0.1 0.1 -0.4 0.2 -0.1 -1.6 -0.7 -0.0 -0.5 -0.5 -0.7 -0.4 -0.5 -0.2 -0.6 -0.2 -0.5 -0.3 -1.0 0.1 -0.4 0.0 -0.6 0.1 -0.4 -0.6 -0.6 -0.4 -0.2 -0.6
HbA1C 0.4 0.4 3.1 0.7 0.7 0.6 -0.0 0.2 0.8 0.4 0.9 0.3 0.8 0.5 0.6 0.4 -0.3 0.7 0.5 0.4 -0.3 0.7 0.7 0.9 -0.4 0.8 0.5 0.9 0.3 0.7 0.3 0.6 0.5 0.7 -0.1 0.7 0.4 0.5 0.6 0.6 0.8 1.8 1.0 0.4 0.9
HDL Cholesterol 0.1 0.2 1.6 0.8 0.0 -0.0 1.3 0.9 -0.3 0.7 0.0 -0.1 -0.7 -0.1 -0.2 -0.4 -0.3 0.5 0.2 -0.1 0.6 -0.3 0.4 -0.2 -0.5 -0.5 -0.0 0.1 -0.3 0.1 0.4 -0.0 -0.3 -0.2 -0.3 0.1 0.1 -0.3 0.4 -0.4 -0.2 -0.1 0.0 -0.1 -0.2
LDL Cholesterol 0.9 1.4 3.9 -1.2 1.1 1.3 -2.0 -0.9 0.8 0.4 0.7 0.9 1.9 0.7 2.0 1.1 -1.1 -1.7 0.6 0.5 -1.5 1.2 -0.3 1.4 -1.2 0.4 1.3 1.2 1.3 1.0 0.1 1.4 1.8 1.3 -1.0 1.1 1.0 1.5 0.7 1.6 1.2 1.0 0.5 0.8 1.9
Lupus 0.7 1.0 4.8 -0.3 -0.8 -0.6 1.3 -1.2 -0.8 -0.8 -1.1 -1.6 -0.6 -0.1 -0.7 0.1 1.3 0.7 -0.5 -1.0 -0.5 0.2 -0.4 -0.3 1.4 1.6 -1.3 -0.8 -2.2 -1.0 -1.1 -1.3 -1.0 0.3 0.7 -0.1 -0.6 -1.7 -1.4 -1.0 -0.9 -1.3 -1.1 -1.1 0.1
Neuroticism (2016) 2.3 3.2 5.7 -1.4 -2.2 -2.2 -0.5 -1.1 -0.6 -2.0 -2.2 -2.3 -1.7 -1.7 -1.9 -1.5 2.0 0.9 -2.2 -2.1 -1.1 -2.1 -1.9 -1.7 1.8 1.1 -2.1 -1.8 -1.9 -1.8 -2.0 -2.1 -2.0 -1.4 2.1 -1.6 -2.1 -1.8 -2.2 -2.0 -1.7 -1.2 -1.9 -2.4 -1.4
Primary Biliary Cirrhosis 0.2 0.3 1.2 0.3 0.5 0.6 0.5 -0.2 0.6 -0.4 0.7 -0.1 0.9 0.5 0.7 0.2 -0.6 -0.4 -0.0 0.0 0.1 -0.3 0.9 0.8 0.2 1.1 0.4 1.0 0.4 0.8 -0.1 0.6 0.6 0.9 0.1 1.1 0.3 0.5 0.5 0.2 0.7 0.8 0.8 0.6 0.8
Rheumatoid Arthritis 0.7 1.0 3.8 1.2 0.5 0.6 1.1 1.6 0.8 1.2 0.3 1.2 0.3 1.1 0.4 2.0 -0.8 0.9 0.9 1.1 -0.2 0.6 1.5 0.6 -1.0 -1.1 0.7 1.0 1.3 1.0 0.9 1.0 0.5 -0.1 -0.8 0.7 0.4 0.9 1.9 0.5 0.5 0.9 1.4 1.3 -0.0
Schizophrenia (2014) 0.1 0.3 2.4 -0.6 0.1 0.4 -0.6 -0.1 0.7 0.3 -0.3 0.4 0.5 0.1 0.4 -0.1 -0.2 -1.5 0.5 0.3 0.2 0.4 -0.2 -0.1 -1.0 -1.1 0.3 -0.1 0.5 -0.1 0.3 0.3 0.4 0.1 -0.9 0.1 0.5 0.2 -0.2 0.5 0.4 -0.6 -0.5 0.6 0.2
Triglycerides 0.3 0.5 3.9 -0.8 0.4 0.4 -2.0 -0.6 1.5 -0.0 -0.1 0.7 0.5 0.2 0.5 0.6 -0.3 -1.6 0.3 0.5 -0.8 0.5 -0.1 0.5 -0.4 -0.4 0.6 0.2 0.6 0.5 -0.2 0.6 0.6 0.4 -0.7 -0.0 0.4 0.8 -0.2 0.9 0.8 -0.4 0.4 0.8 0.3
Type 2 Diabetes (T2D) (2012) 0.2 0.3 1.1 0.3 0.4 0.4 -0.8 -0.6 0.5 -0.4 0.6 0.6 0.9 0.1 0.2 -0.0 0.8 -0.8 -0.0 -0.5 0.5 0.3 -0.5 0.4 0.8 1.0 0.2 0.1 0.0 -0.2 0.3 0.1 0.5 1.1 0.3 0.3 0.5 -0.3 0.2 0.3 0.3 -0.6 -0.4 0.1 0.9
Ulcerative Colitis 0.4 0.6 4.4 -0.7 0.2 0.3 -0.6 -0.8 0.2 -0.6 0.4 0.4 1.0 -0.1 1.1 0.6 -0.7 -0.8 -0.1 0.2 -0.7 -0.9 0.1 1.2 -0.8 2.1 0.7 0.8 0.8 0.8 -0.6 0.7 0.9 0.9 0.2 0.3 0.6 1.2 0.0 0.8 0.7 1.8 0.8 0.2 1.1
Blood Eosinophil Count 0.0 0.2 2.0 -0.3 -0.4 -0.2 1.4 0.3 -0.1 -0.2 0.2 0.3 -0.3 0.0 -0.1 -0.7 -0.4 -0.8 -0.2 0.4 -1.3 -0.1 0.4 -0.0 -0.1 0.4 0.2 0.2 0.6 0.6 -0.3 0.1 -0.0 0.1 -0.3 -0.1 -0.2 0.6 0.2 0.0 0.3 0.4 0.6 0.0 -0.3
Blood Platelet Count 0.1 1.6 8.6 0.2 0.7 1.4 -0.3 -1.2 -1.0 0.3 2.4 -0.6 0.1 1.2 0.9 0.2 -1.0 0.8 2.9 1.6 0.1 1.0 0.7 2.6 -0.8 0.6 0.4 0.8 -1.2 1.0 -0.3 0.5 1.0 2.9 -1.2 0.8 2.1 0.1 -0.4 1.2 1.1 1.5 0.7 0.6 2.4
Blood Red Count 0.3 3.3 16.5 -3.2 -0.4 -0.5 -3.5 -3.6 0.5 -3.6 0.6 -1.3 0.5 -1.3 1.2 -1.5 0.8 -3.5 -2.9 -2.2 -1.3 -0.2 -1.4 1.5 1.2 4.1 0.0 0.5 0.2 0.1 -1.6 -0.2 1.1 2.7 2.9 0.3 0.7 1.1 -1.5 1.1 0.2 1.5 -0.3 -0.7 2.1
Blood White Count 0.1 1.0 5.1 0.1 0.9 1.2 0.5 -0.8 0.1 -0.3 2.2 0.3 1.0 0.8 1.4 0.3 -1.0 -1.0 0.9 0.6 -0.1 0.5 0.7 2.2 -1.0 1.3 0.8 1.3 0.2 1.0 0.6 0.9 1.2 1.6 -0.4 1.8 1.2 0.7 0.6 0.4 0.6 0.4 0.9 0.6 1.7
Heel T-Score 0.1 1.0 2.6 -1.0 -1.1 -1.3 0.5 -0.6 -0.1 -1.0 -0.8 -1.0 -1.4 -1.0 -1.1 -0.3 1.2 0.1 -1.5 -1.4 0.1 -1.3 -0.8 -0.8 0.8 0.8 -1.0 -1.1 -0.6 -1.1 -0.9 -1.1 -1.3 -1.1 1.2 -0.9 -1.2 -0.6 -0.5 -1.1 -0.8 -1.6 -1.3 -0.9 -1.1
BMI 0.4 2.1 8.8 0.8 1.8 1.9 0.1 -0.1 0.3 0.5 2.3 0.7 1.9 1.3 1.7 1.0 -1.2 -1.3 1.7 0.7 -0.1 0.9 1.4 2.0 -0.8 2.4 1.5 1.7 0.2 1.2 1.1 1.2 1.5 3.0 -0.6 2.0 2.1 1.0 0.8 1.4 1.4 1.4 0.7 1.0 2.6
Height 0.0 0.8 12.1 -0.2 -0.9 -0.8 -0.1 0.3 0.8 -0.3 -0.3 -0.2 -1.0 0.4 -0.9 -0.7 1.0 3.5 -0.4 0.3 2.9 -0.0 -0.6 -0.4 1.2 1.1 -0.4 -0.7 0.5 -0.1 -0.5 -0.5 -0.5 0.8 0.3 -0.6 -0.4 0.0 -0.7 0.5 0.5 -1.2 -0.4 -0.3 -0.3
Waist Hip Ratio (WHR) 0.5 2.0 6.4 -0.6 -1.4 -1.7 0.1 -1.2 -1.2 -1.6 -0.9 -2.2 -0.8 -1.2 -1.4 -0.5 1.9 0.3 -1.8 -1.8 0.9 -1.3 -0.9 -0.8 2.5 1.4 -1.8 -1.4 -1.8 -1.4 -1.2 -1.9 -1.6 -0.5 2.3 -1.1 -1.6 -1.7 -1.5 -1.5 -1.2 -0.6 -1.3 -1.7 -0.9
Systolic Blood Pressure 2.7 13.7 30.5 -3.4 -4.5 -4.6 -2.8 -2.8 1.6 -4.0 -3.2 -3.9 -3.4 -3.4 -4.2 -4.0 5.5 -1.2 -4.4 -4.2 -1.8 -3.5 -3.9 -5.1 5.0 3.1 -3.8 -4.5 -2.6 -4.1 -3.6 -4.4 -3.5 -1.1 3.9 -4.7 -4.0 -3.1 -4.7 -1.7 -2.0 -2.0 -4.6 -4.0 -2.7
Smoking Status 0.2 0.4 1.8 -0.8 0.1 0.3 1.1 -0.7 -1.4 -0.1 0.3 -0.2 0.7 0.0 0.7 0.6 -0.3 -0.6 0.3 0.1 -0.8 0.5 -0.2 1.0 -0.9 0.9 0.2 0.5 -0.1 0.4 -0.1 0.4 0.6 1.1 0.2 0.7 1.2 0.7 0.2 0.6 0.4 0.9 0.1 0.3 1.3
Allergy or Eczema 0.4 0.9 4.2 -1.1 -0.9 -1.2 -0.5 -1.1 -0.1 -1.7 -1.1 -1.4 -0.2 -0.7 -0.7 -0.7 1.1 -0.6 -2.0 -1.5 0.5 0.1 -0.9 -0.0 0.9 1.1 -0.9 -0.9 -0.6 -0.9 -0.6 -1.0 -0.6 -0.2 1.8 -0.9 -0.6 -0.7 -1.5 -0.6 -0.9 -0.6 -0.9 -0.8 -0.6
Cardiovascular Disease 0.4 1.4 4.7 -0.3 -1.3 -1.2 0.5 -0.8 1.6 -1.4 -0.8 -1.0 -0.4 -0.7 -1.1 -1.6 2.2 -0.2 -1.3 -1.3 -1.4 -1.2 -1.4 -1.8 2.2 1.4 -1.1 -1.5 -0.5 -1.5 -0.8 -1.4 -0.9 -0.3 0.7 -1.5 -1.0 -1.1 -0.5 -0.6 -0.4 -0.4 -1.9 -1.1 -0.6
Hypothyroidism (self reported) 1.3 3.0 8.2 0.9 1.9 2.0 0.0 1.3 1.8 2.2 1.8 1.7 2.5 1.7 1.9 2.5 -1.8 1.2 1.7 1.7 0.1 2.9 1.8 1.7 -2.0 -0.5 1.8 1.9 1.2 1.6 1.3 1.9 1.8 1.2 -1.8 1.8 1.9 1.5 1.9 1.6 1.3 1.6 1.5 2.0 1.7
Respiratory disease 0.1 0.2 1.7 0.9 0.1 0.1 0.9 0.4 0.9 0.5 0.3 -0.5 -0.1 0.2 -0.1 -0.2 -0.2 1.3 0.7 0.2 -0.1 -0.1 0.1 0.0 0.0 -0.9 -0.2 -0.0 -0.5 0.0 -0.5 -0.1 -0.3 -0.6 -0.3 -0.0 -0.5 -0.5 0.0 -0.6 -0.5 -0.5 0.2 -0.1 -0.4
Type 2 Diabetes (T2D) (2018) 0.2 0.4 3.0 -0.6 -0.4 -0.1 0.2 -1.3 -1.7 -1.0 0.2 -0.7 0.8 -0.2 0.2 0.0 -0.2 0.5 0.3 -0.5 -1.2 -1.1 -0.6 -0.0 0.8 0.9 -0.1 0.1 -0.7 0.1 -0.9 -0.0 0.1 0.6 0.4 -0.1 0.4 0.2 0.1 -0.3 0.2 1.3 -0.4 -0.3 0.8
Lung FEV1/FVC ratio 0.2 0.8 8.2 -0.8 -0.3 -0.4 -1.5 0.1 0.7 -0.8 -0.2 1.0 -0.1 0.3 0.1 1.4 0.5 -2.9 -1.3 -0.1 0.5 -0.3 -0.2 0.3 0.7 0.6 0.7 0.3 1.8 0.8 0.2 0.6 0.6 1.1 0.6 -0.6 0.6 1.6 0.5 1.3 1.1 1.3 0.5 0.6 0.5
Lung FVC 0.8 4.1 14.2 2.2 2.6 2.6 1.5 2.0 -1.0 2.5 2.0 1.7 1.8 2.6 2.0 1.4 -2.3 3.8 2.0 1.8 1.2 2.8 2.4 1.7 -3.3 -0.4 1.9 2.3 1.5 1.9 1.9 1.9 1.7 1.4 -2.1 3.0 1.5 1.0 1.7 1.6 1.8 1.1 2.0 1.8 1.7
Neuroticism 0.2 0.5 1.9 -0.1 -0.8 -0.7 0.0 -0.3 0.6 -0.3 -0.3 -1.2 -0.5 -0.7 -0.6 -0.4 0.8 0.8 -0.2 -0.8 -0.9 -0.6 -0.3 -0.3 0.2 0.3 -1.1 -0.7 -1.4 -0.7 -0.7 -0.9 -0.8 -0.7 0.7 -0.5 -0.7 -1.2 -1.0 -0.9 -0.6 0.2 -0.7 -0.8 -0.3
Chronotype (morning person) 1.0 2.3 5.4 -0.6 1.8 1.8 -1.1 -0.2 1.1 0.9 1.5 1.6 1.8 0.9 1.8 0.9 -1.5 -2.0 1.1 1.2 1.2 1.7 0.7 1.9 -1.5 0.2 1.9 1.5 1.2 1.6 0.6 1.8 2.0 2.1 -1.3 1.2 2.0 2.0 0.6 2.3 1.9 1.9 1.1 1.8 2.0
Hair Pigment 0.0 1.0 3.1 1.7 1.0 1.1 0.9 1.0 0.1 1.1 1.2 0.5 0.2 1.1 0.6 1.7 -0.9 1.2 1.5 0.9 1.4 0.8 1.8 0.8 -0.6 -0.5 0.7 1.0 -0.1 1.0 1.0 0.6 0.5 1.1 -0.9 1.0 1.0 0.3 1.2 0.3 0.7 1.5 1.0 0.7 0.8
Tanning 0.0 0.3 0.9 -0.7 -0.4 -0.6 -0.7 -0.5 0.5 -0.5 -0.6 0.1 -0.2 -0.8 -0.2 -0.6 0.1 -0.2 -0.3 -0.7 -0.7 -0.8 -1.0 -0.0 0.2 -0.1 -0.2 -0.4 0.4 -0.2 -0.4 -0.1 -0.2 -0.9 0.7 -0.7 -0.5 0.1 -0.6 -0.3 -0.5 0.1 -0.2 -0.7 -0.5
Hand grip strength (left) 1.0 2.7 6.2 0.9 2.0 2.0 -0.8 0.7 0.4 1.3 1.9 1.8 1.4 2.0 1.8 2.3 -1.4 0.2 1.7 1.7 0.3 1.3 1.7 1.4 -1.1 0.2 1.9 1.6 1.7 1.8 2.0 1.7 1.9 2.3 -1.4 1.8 2.5 1.6 1.8 2.1 2.1 0.4 1.3 2.1 1.8
Number of treatments/medications taken 0.4 0.7 6.8 -0.6 0.4 0.8 -1.7 -1.5 -0.3 -0.7 0.5 -0.5 1.9 0.3 0.8 0.1 0.2 -0.6 0.1 -0.3 -2.6 0.5 -0.5 0.6 0.4 1.8 0.2 0.3 -0.8 -0.3 -0.4 0.1 0.5 1.0 -0.2 0.8 0.2 -0.1 -0.4 0.1 0.4 0.1 -0.7 -0.1 1.4
Average weekly spirits intake 0.1 0.2 2.1 -0.6 -0.2 -0.2 -0.5 -0.2 -1.4 0.1 -0.5 0.1 -0.0 0.1 -0.3 -0.8 0.3 0.5 -0.3 0.2 0.6 0.4 -0.5 0.2 -0.3 -0.4 -0.0 -0.5 -0.4 -0.3 -0.3 -0.1 -0.1 -0.4 -0.1 -0.8 0.4 -0.1 -0.3 0.1 -0.3 0.1 -0.1 0.2 -0.4
Sensitivity / hurt feelings 0.4 0.6 2.4 1.1 0.7 0.7 -0.5 1.0 1.3 0.7 1.1 0.5 0.3 0.4 0.3 0.8 -0.9 1.3 1.2 0.7 1.6 0.0 0.9 0.7 -1.3 -0.1 0.7 0.8 0.2 0.9 0.5 0.6 0.2 0.2 -0.7 0.5 0.3 0.5 0.9 0.1 0.7 1.5 0.8 0.4 0.4
Frequency of depressed mood in last 2 weeks 0.4 0.6 3.5 0.4 1.0 1.2 -0.6 -0.2 1.9 0.6 0.7 0.4 1.4 0.8 0.8 1.1 -0.1 0.7 1.0 0.6 0.9 1.3 0.0 1.1 -0.4 0.5 0.6 0.4 -0.3 0.1 1.1 0.4 0.7 0.9 -0.8 0.9 0.7 -0.2 -0.5 0.7 0.8 -0.2 -0.1 0.3 1.1
Hearing difficulty/problems: Yes 1.1 1.6 6.2 -1.7 -1.2 -1.3 -1.0 -2.0 -0.9 -2.5 -0.9 -1.0 -0.3 -1.4 -0.5 -1.3 1.0 -1.6 -2.3 -1.8 -1.7 -1.5 -1.7 -0.3 1.3 1.9 -0.8 -0.8 -0.3 -0.9 -1.4 -0.9 -0.6 -0.8 2.0 -1.1 -0.9 -0.3 -0.9 -1.1 -1.4 0.0 -1.0 -1.6 -0.4
Relative age of first facial hair 0.1 0.2 3.4 0.2 0.2 0.2 0.2 0.2 0.3 0.1 0.4 0.3 0.4 0.4 0.1 1.8 0.3 -0.4 0.0 0.1 0.4 0.5 0.4 0.4 -0.5 0.3 0.2 0.4 -0.2 0.2 1.0 0.2 0.0 0.4 -0.0 0.4 0.7 0.2 0.0 0.2 0.1 0.1 0.3 0.3 0.4
Other serious medical condition/disability diagnosed by doctor 0.9 1.2 6.5 -1.8 -0.1 0.1 -0.6 -2.5 1.3 -2.0 -0.4 -1.1 1.7 -0.8 0.8 -0.1 0.3 -0.8 -0.6 -1.2 -2.5 -0.1 -1.5 1.0 -0.1 2.3 -0.5 0.0 -1.1 -0.6 -1.6 -0.4 0.5 0.7 1.2 0.8 -0.4 -0.7 -1.3 -0.4 -0.4 -0.0 -0.7 -0.9 1.1
Ever used hormone-replacement therapy (HRT) 0.2 0.3 1.4 -0.5 0.3 0.5 0.7 0.1 -0.6 0.5 0.1 0.3 0.0 0.0 0.6 -0.2 -0.9 -1.2 0.3 0.5 -1.1 0.4 -0.4 0.5 -0.9 -0.4 0.6 0.3 0.4 0.4 -0.1 0.6 0.5 -0.2 -0.9 0.1 0.1 0.6 -0.4 0.5 0.5 1.2 0.3 0.3 0.3
Ever had hysterectomy (womb removed) 0.4 0.5 2.9 -0.9 -0.5 -0.6 -0.3 -1.1 -1.0 -0.9 -0.6 -0.6 0.4 -0.2 -0.0 -1.3 0.7 -1.7 -0.6 -1.0 0.1 -0.1 -0.7 -0.3 0.7 1.1 -0.2 -0.5 -0.2 -0.4 -0.8 -0.3 0.0 0.7 1.1 -0.5 0.2 0.2 -1.0 0.2 0.1 0.1 -0.8 -0.2 0.3
Systolic blood pressure, automated reading 0.9 2.5 8.4 -1.1 -1.7 -1.6 -1.4 -0.7 1.1 -1.1 -1.1 -1.3 -1.7 -1.1 -2.1 -2.4 2.9 -0.1 -1.3 -1.0 0.2 -1.2 -1.6 -2.7 2.3 1.4 -1.5 -2.2 -1.2 -1.9 -1.5 -2.1 -1.6 0.2 0.7 -2.3 -1.6 -1.7 -2.5 -0.0 -0.4 -1.0 -2.1 -1.6 -1.2
Eye problems/disorders: Diabetes related eye disease 1.3 1.5 7.1 -1.5 -1.1 -0.6 -0.5 -1.6 -2.7 -0.9 -1.1 -1.9 -0.5 -1.1 -0.9 -0.8 0.8 0.5 0.1 -0.5 -1.5 -1.6 -1.3 -1.0 0.4 -0.0 -1.4 -1.2 -2.2 -1.4 -1.5 -1.3 -1.1 -0.4 0.2 -0.6 -1.0 -1.6 -2.0 -1.0 -1.0 -1.1 -1.5 -1.2 -0.5
Angina 0.8 1.0 4.3 0.8 -0.6 -0.5 1.5 0.6 -0.4 0.7 -0.5 -1.0 -0.2 -0.5 -1.1 -1.2 0.9 2.1 0.8 -0.4 1.3 -0.7 -0.3 -1.1 -0.0 -0.6 -1.1 -1.2 -1.2 -1.5 -0.5 -1.0 -1.2 -1.4 -0.2 -0.6 -0.9 -1.7 -0.6 -1.1 -1.0 -1.5 -1.2 -0.7 -1.0
Medication for hormone replacement therapy 0.2 0.3 2.3 -0.1 -0.0 -0.0 0.2 0.4 0.4 -0.1 -0.4 0.6 -0.4 -0.3 0.1 0.2 -0.3 -1.5 -0.8 0.3 -0.4 0.2 0.2 0.9 0.4 -0.6 0.5 0.4 0.9 0.9 0.3 0.5 0.2 0.1 -0.1 -0.2 0.1 1.1 0.9 0.4 0.5 0.6 0.5 0.7 0.0
Vitamin and mineral supplements 0.4 0.6 2.9 -0.3 0.7 0.9 0.8 -0.9 -0.8 -0.1 0.5 -0.4 1.6 0.6 1.1 -0.3 -0.2 0.6 0.8 -0.0 0.0 0.7 0.3 1.4 0.2 1.7 0.2 0.6 -0.6 0.3 -0.6 0.3 0.8 1.6 -0.1 1.2 0.4 -0.3 -0.4 0.7 0.6 0.2 0.1 0.2 1.5
Supplements: Zinc 0.2 0.3 3.4 -1.0 -0.4 -0.3 -1.0 -0.4 0.2 -0.1 -0.3 -0.0 -1.0 -0.5 -0.3 0.5 0.5 -1.8 -0.5 -0.0 -0.5 0.1 -0.7 -0.4 -0.1 -0.7 -0.2 -0.4 -0.0 -0.4 0.0 -0.2 -0.3 0.3 -0.0 -0.5 -0.1 0.0 -0.8 0.4 -0.0 -0.2 -0.5 -0.1 -0.0
Medication: Co-codamol 2.2 2.6 7.4 -0.3 -1.5 -1.4 0.7 -0.3 0.4 -0.4 -1.2 -2.1 -1.4 -1.3 -2.3 -1.5 2.3 0.9 -1.1 -0.7 -0.2 -1.2 -1.3 -1.9 0.9 0.1 -2.1 -2.3 -2.6 -2.1 -1.0 -2.3 -2.2 -1.0 0.5 -1.8 -1.9 -2.7 -2.6 -1.2 -1.4 -1.9 -2.0 -1.6 -1.6
Medication: Metformin 1.1 1.6 4.5 0.1 1.1 1.5 1.0 0.3 -1.0 1.2 1.1 1.0 1.7 1.2 1.5 1.0 -1.4 0.4 1.6 1.4 1.0 1.2 0.4 1.0 -1.2 0.1 1.4 1.3 0.8 1.1 0.2 1.4 1.5 2.0 -1.8 1.0 1.8 1.2 0.6 1.9 1.8 2.1 0.7 1.2 1.9
Diabetes (father) 0.2 0.3 1.4 -0.2 0.0 0.1 -1.1 0.1 -1.2 0.5 -0.8 -0.5 -0.3 -0.6 -0.2 0.6 -0.2 -0.7 1.0 -0.1 0.6 0.0 -0.1 -0.6 -0.0 -1.1 -0.3 -0.2 -0.4 -0.2 0.2 -0.2 -0.3 -0.5 -0.2 0.1 -0.3 -0.4 -0.3 -0.2 -0.4 -1.1 -0.2 -0.4 -0.2
Diabetes (mother) 1.1 1.4 4.7 1.3 1.5 1.4 0.1 1.8 0.3 1.9 0.5 1.2 0.4 1.6 0.6 0.8 -1.1 0.7 1.8 1.8 -0.6 0.7 1.3 0.4 -1.2 -1.9 1.3 0.8 1.1 0.9 2.2 1.0 0.8 0.4 -1.8 1.1 1.1 0.5 0.9 1.1 1.0 -0.5 1.1 1.3 0.2
Severe depression (siblings) 0.8 0.9 2.9 -1.2 -0.9 -0.8 -0.7 -1.0 1.0 -1.1 -1.7 -0.7 -0.4 -1.2 -0.9 -0.3 0.8 -0.8 -1.4 -0.7 -0.8 -0.6 -1.5 -0.8 0.7 -0.1 -0.7 -1.0 -0.6 -1.0 -0.7 -0.8 -0.8 -1.2 0.4 -1.1 -1.0 -0.6 -0.9 -0.9 -0.7 -1.2 -0.9 -1.1 -0.9
Pack years adult smoking proportion 1.1 1.6 7.4 -2.0 -0.6 -0.3 -2.7 -2.6 -1.6 -1.9 -0.4 -1.7 0.8 -1.1 0.3 -1.4 1.0 -1.0 -0.7 -1.4 -1.3 -1.2 -1.7 0.4 0.5 2.3 -0.6 -0.3 -1.6 -0.9 -1.7 -0.8 -0.1 1.1 1.4 -0.1 -0.3 -0.3 -1.8 -0.3 -0.5 0.7 -1.3 -1.5 1.4
Impedance of leg (right) 1.6 7.8 16.0 -2.1 -3.5 -3.6 -0.8 -0.8 0.7 -1.9 -2.5 -2.4 -3.3 -2.9 -3.3 -3.3 3.0 -0.2 -3.5 -2.6 -0.0 -3.1 -3.1 -3.2 3.7 -1.7 -3.1 -3.3 -1.4 -3.0 -2.4 -2.9 -3.0 -4.0 2.3 -3.4 -3.6 -2.3 -2.2 -2.7 -3.1 -3.0 -2.6 -2.8 -3.8
Leg fat-free mass (left) 1.1 5.8 14.2 1.7 2.9 3.1 0.6 1.1 -0.3 2.0 2.4 2.1 2.3 2.9 2.5 2.7 -2.3 1.0 3.4 2.8 1.7 2.7 2.3 3.0 -2.9 1.4 2.6 2.5 1.3 2.5 1.9 2.3 2.5 3.8 -2.5 2.7 3.1 1.9 1.6 2.8 3.0 1.8 2.0 2.5 3.0
Trunk fat percentage 0.2 0.8 6.0 -0.7 -0.5 -0.2 -0.3 -1.2 0.7 -1.1 0.4 -0.9 0.3 -0.5 -0.2 -1.6 1.2 -0.2 -0.1 -0.7 2.2 -0.5 -0.9 0.1 1.1 2.5 -0.5 -0.5 -1.1 -0.9 -0.9 -0.8 -0.4 0.9 0.6 0.2 -0.2 -0.8 -1.0 -0.3 -0.4 -1.0 -1.3 -0.8 0.7
Hand grip strength (right) 1.4 3.9 10.2 1.9 2.3 2.1 -0.6 1.7 0.3 1.9 2.0 2.3 1.5 2.4 2.0 3.2 -1.7 1.1 1.7 1.9 -0.4 1.8 2.5 1.4 -1.3 0.1 2.3 2.0 2.3 2.1 2.8 2.1 2.2 2.2 -1.6 2.1 2.6 1.8 2.3 2.3 2.4 1.2 1.8 2.4 1.9
Townsend deprivation index at recruitment 0.7 1.0 3.8 -0.8 -0.7 -0.5 -0.4 -1.7 0.7 -1.8 -0.5 -1.2 -0.5 -0.8 -0.5 -0.4 1.2 -0.4 -0.4 -1.0 0.1 -0.5 -1.1 -0.0 1.7 1.5 -1.0 -0.8 -1.4 -1.1 -0.8 -1.2 -0.7 0.3 1.1 -0.2 -0.9 -1.3 -1.9 -1.0 -0.6 -1.3 -1.2 -1.4 -0.1
Current tobacco smoking 0.2 0.4 3.0 -0.1 0.4 0.5 0.6 -0.7 -1.0 -0.2 0.9 -0.0 0.5 0.3 0.8 -0.4 -0.5 0.1 0.6 0.1 -0.9 0.0 -0.0 1.7 -0.1 1.4 0.2 0.7 -0.4 0.5 -0.1 0.3 0.5 0.8 0.2 0.9 0.7 0.3 0.7 -0.1 0.2 0.6 0.4 -0.1 1.1
Average weekly fortified wine intake 0.5 0.6 2.3 0.1 -0.7 -0.7 -0.4 0.7 0.5 0.3 -0.4 -0.2 -1.3 -0.3 -1.0 -0.9 0.6 -0.1 0.2 0.5 1.5 -0.7 0.1 -0.9 0.9 -1.1 -0.8 -0.7 -0.7 -0.3 -0.4 -0.7 -1.1 -1.4 0.0 -0.9 -1.1 -0.7 -0.7 -0.9 -0.7 -0.3 0.1 -0.4 -1.5
Maternal smoking around birth 0.5 0.7 3.6 1.1 0.7 0.6 1.7 1.4 -0.4 1.4 -0.3 1.0 -0.4 1.0 0.0 0.8 -0.7 0.7 1.7 1.0 1.6 0.6 0.9 0.6 -1.0 -1.9 0.7 0.1 0.6 0.6 0.4 0.5 0.2 -0.5 -1.0 0.2 0.3 0.2 0.8 0.2 0.1 -1.0 0.6 0.7 -0.4
Fed-up feelings 0.5 0.8 4.3 0.6 0.9 1.0 -1.5 -0.6 1.1 -0.3 1.2 -0.1 1.7 1.0 1.2 0.9 0.0 1.1 0.8 0.1 0.4 0.5 0.5 1.4 0.3 2.1 0.4 0.8 -0.2 0.5 0.7 0.4 0.9 1.7 0.3 1.5 1.2 -0.0 -0.0 0.4 0.7 0.3 0.3 0.3 1.7
Frequency of unenthusiasm / disinterest in last 2 weeks 0.3 0.4 3.0 0.6 0.7 0.7 -0.8 0.6 1.5 0.8 0.6 0.3 0.6 1.0 0.5 0.2 -0.3 0.2 0.6 0.7 0.7 0.7 0.4 0.5 -0.2 0.3 0.5 0.4 0.2 0.2 1.1 0.3 0.4 0.5 -0.7 0.2 0.5 0.1 0.2 0.6 0.9 1.7 0.3 0.4 0.4
Relative age voice broke 0.3 0.5 5.3 0.7 -0.0 -0.1 -0.5 0.9 2.3 0.6 -0.1 -0.0 -0.1 1.0 -0.6 0.9 0.2 1.0 0.7 0.5 1.5 -0.2 0.5 -0.6 -0.6 -0.3 -0.1 -0.2 -0.2 -0.2 1.6 -0.2 -0.4 0.0 -0.5 -0.1 0.4 -0.3 -0.6 -0.0 -0.0 -0.8 0.3 -0.2 -0.6
Taking other prescription medications 0.8 1.2 8.5 0.5 1.1 1.4 0.6 -0.6 -0.5 -0.2 1.2 -0.0 2.9 0.7 1.6 1.3 -0.9 0.7 1.0 0.1 -0.5 0.8 0.6 1.5 -0.3 2.5 0.6 1.4 -0.4 0.5 -0.0 0.7 1.2 1.4 -0.1 2.0 1.0 0.3 0.5 0.1 0.4 1.5 0.4 0.5 2.0
Age when periods started (menarche) 0.4 1.0 14.0 -1.2 -1.1 -0.9 -0.4 -1.1 -1.2 -1.3 -0.7 -0.7 0.1 -0.9 0.0 -0.9 0.3 -0.4 -1.3 -1.0 -3.7 -0.5 -0.8 0.0 1.1 1.2 -0.8 -0.1 -0.4 -0.3 -1.9 -0.5 -0.3 -0.2 1.2 -0.3 -0.6 -0.1 -0.3 -0.6 -0.8 0.7 -0.2 -0.9 -0.0
Bilateral oophorectomy (both ovaries removed) 1.8 2.1 7.3 -2.1 -1.8 -1.7 -0.5 -1.9 -1.3 -1.7 -1.0 -1.8 -0.9 -0.9 -1.2 -2.7 2.1 -1.4 -2.0 -1.7 -0.8 -0.6 -1.2 -1.1 1.8 1.8 -1.5 -1.6 -1.7 -1.4 -1.7 -1.5 -1.1 0.5 1.8 -1.5 -0.5 -1.1 -2.0 -0.2 -0.8 -0.5 -1.8 -0.9 -0.2
Heel bone mineral density (BMD) T-score, automated (left) 0.1 0.2 1.2 0.5 -0.1 -0.1 1.0 0.8 0.6 0.7 0.2 0.3 -0.7 0.1 -0.5 0.9 -0.3 0.2 1.0 0.2 -0.3 -0.8 0.5 -0.1 -0.3 -1.1 -0.0 -0.3 0.3 -0.2 0.5 -0.0 -0.3 -0.4 -0.5 -0.3 -0.2 -0.1 0.3 -0.1 0.1 -0.6 -0.3 0.3 -0.6
Tinnitus: Yes, but not now, but have in the past 0.2 0.3 2.0 -0.1 -0.2 -0.2 1.1 -0.5 0.8 -0.3 -0.1 -0.3 0.2 0.0 -0.1 -0.2 0.5 0.1 -0.5 -0.5 -0.5 -0.8 -0.7 -0.4 1.4 0.8 -0.4 -0.5 -0.6 -0.6 -0.3 -0.4 -0.1 0.1 0.4 -0.6 -0.1 -0.5 -0.4 -0.2 -0.2 0.1 -0.8 -0.5 0.1
Qualifications: CSEs or equivalent 0.7 0.9 4.9 2.0 0.2 -0.1 2.0 2.2 0.5 1.3 -0.2 0.4 -1.4 1.0 -1.0 -0.1 -0.0 1.2 0.7 0.8 1.4 0.3 1.5 -0.9 0.6 -1.6 0.0 -0.2 0.4 0.4 1.1 -0.2 -0.8 -0.4 -0.3 -0.2 -0.3 -0.5 0.7 -0.1 0.1 -1.8 0.7 0.5 -1.4
Serious illness, injury or assault to yourself 1.1 1.3 4.1 -1.4 -0.8 -0.6 -2.0 -1.7 -0.3 -1.4 -1.9 -1.4 -0.3 -1.3 -0.6 -1.0 1.0 0.9 -0.8 -0.9 -0.4 -1.2 -1.5 -0.7 0.1 0.9 -0.9 -1.2 -1.3 -1.2 -1.2 -1.2 -0.7 -0.2 0.7 -0.6 -1.2 -1.2 -2.0 -0.8 -0.9 -1.7 -1.5 -1.3 -0.4
High blood pressure 0.8 2.3 6.7 -1.2 -1.6 -1.3 -1.3 -1.7 1.5 -1.9 -0.7 -1.3 -0.9 -0.9 -1.5 -2.6 2.6 -0.2 -1.2 -1.2 -0.3 -1.5 -2.1 -2.1 2.6 1.4 -1.3 -2.0 -1.3 -2.0 -1.4 -1.7 -1.2 0.3 0.7 -1.9 -1.3 -1.4 -1.9 -0.4 -0.4 -1.1 -2.5 -1.5 -0.4
Hayfever, allergic rhinitis or eczema 0.2 0.4 2.2 -0.5 -0.4 -0.7 0.4 -0.5 1.5 -1.0 -0.5 -1.0 0.1 -0.3 -0.4 -0.1 0.7 -0.2 -1.4 -1.0 0.8 0.4 -0.3 0.5 0.6 1.1 -0.6 -0.4 -0.3 -0.3 -0.2 -0.6 -0.3 0.4 1.5 -0.2 -0.1 -0.5 -1.0 -0.1 -0.4 -0.6 -0.3 -0.5 -0.2
Multivitamins +/- minerals 0.3 0.4 1.6 0.4 -0.7 -1.0 -0.0 0.8 0.5 -0.1 -0.5 0.3 -1.2 -0.7 -0.9 0.3 0.4 -0.4 -1.0 -0.6 0.5 -0.6 -0.3 -1.2 0.1 -0.9 -0.3 -0.6 0.5 -0.2 0.1 -0.3 -0.7 -1.3 0.7 -0.9 -0.4 0.3 0.7 -0.8 -0.7 -0.5 -0.3 -0.3 -1.2
Stomach or abdominal pain in last month 0.4 0.6 5.1 1.4 -0.4 -0.6 1.7 0.7 0.6 0.2 -0.8 -0.7 -1.0 0.3 -0.7 0.1 0.1 2.2 0.1 -0.3 -0.5 -0.4 0.5 -0.1 1.1 -0.2 -0.7 -0.4 -0.5 -0.2 0.2 -0.6 -0.7 -0.9 0.6 -0.2 -0.6 -0.9 0.4 -1.0 -0.8 -0.3 0.3 -0.6 -0.8
Supplements: Glucosamine 1.1 1.4 4.8 2.0 0.8 0.8 0.6 2.2 1.1 2.1 0.7 1.3 -0.1 1.3 -0.4 1.7 -0.7 1.1 1.9 1.8 1.5 1.0 1.4 -0.2 -1.9 -1.7 0.8 0.1 0.9 0.6 2.2 0.7 0.1 -0.6 -1.8 -0.0 0.6 0.2 1.7 0.2 0.6 -0.8 0.6 1.0 -0.6
Diverticular disease/diverticulitis (self-reported) 2.3 2.7 7.6 -0.7 -1.3 -1.4 0.3 -1.2 -2.2 -1.2 -1.7 -2.5 -0.9 -1.2 -1.4 -2.8 1.3 1.3 -1.2 -1.6 -1.2 -2.0 -1.1 -1.1 2.1 -0.3 -2.0 -1.5 -2.5 -2.0 -1.6 -1.9 -1.7 -2.0 1.5 -1.2 -1.7 -2.1 -1.4 -2.2 -2.3 -0.5 -1.5 -1.7 -1.5
Medication: Atenolol 0.9 1.1 4.7 -1.9 0.2 0.4 0.1 -1.6 1.3 -1.3 0.3 0.2 1.9 0.1 1.1 -0.9 0.1 -2.2 -0.9 -0.5 -1.3 1.1 -0.7 0.4 0.2 1.6 0.6 0.5 0.9 0.4 -0.2 0.6 1.2 2.1 0.4 0.9 0.5 1.0 -0.8 1.5 1.1 -0.1 -0.0 0.4 1.7
Medication: Levothyroxine sodium 0.4 0.6 3.6 -0.8 -0.5 -0.4 -0.5 -0.9 -0.0 -0.4 -0.5 -1.1 1.4 -0.4 0.3 0.9 0.8 0.7 -0.8 -1.1 -1.9 0.5 -0.8 0.2 0.7 1.3 -0.8 -0.2 -1.2 -1.0 -1.6 -0.4 -0.1 0.2 0.9 0.3 -0.3 -0.5 -0.6 -0.3 -0.9 0.7 -1.0 -0.5 0.7
Sitting height 0.8 5.7 12.3 1.9 2.4 2.6 2.0 1.6 0.1 2.2 2.9 2.7 1.7 2.7 2.3 2.7 -2.0 1.3 2.9 3.2 2.6 2.9 2.1 3.5 -1.7 0.3 2.5 2.4 2.3 2.9 1.9 2.5 2.4 2.9 -2.4 2.3 2.6 2.3 2.5 2.7 2.7 1.1 2.6 2.5 2.5
Chronic bronchitis/emphysema (father) 0.3 0.3 2.2 0.4 0.4 0.6 0.5 0.1 0.6 0.6 0.4 -0.6 -0.1 0.5 -0.5 -0.7 0.1 0.5 0.9 0.6 0.1 -0.0 0.1 0.1 -0.8 -0.4 -0.3 -0.4 -1.4 -0.5 -0.4 -0.5 -0.4 0.3 -0.9 0.2 -0.3 -1.3 -1.5 -0.0 -0.2 -0.9 -0.4 -0.1 0.1
High blood pressure (mother) 0.7 1.0 4.7 -1.7 -0.4 -0.4 -1.4 -1.6 -0.6 -1.7 0.2 -0.1 0.8 0.2 0.4 -0.8 0.8 -1.5 -2.2 -0.9 -0.8 0.5 -0.8 0.1 1.9 2.0 0.3 0.1 1.0 0.3 -0.4 0.3 0.8 1.8 1.1 0.2 0.7 1.0 -0.6 1.2 0.8 -0.7 -0.2 0.3 1.2
Body mass index (BMI) 0.3 1.3 5.6 0.6 1.5 1.7 -0.0 -0.2 -0.1 0.7 1.5 0.5 1.5 1.0 1.3 0.5 -0.7 -0.8 1.9 0.9 0.9 0.9 0.8 1.5 -1.4 1.6 1.2 1.1 -0.1 0.7 0.6 0.8 1.1 2.4 -0.9 1.5 1.7 0.5 0.3 1.3 1.1 0.7 0.3 0.9 2.1
Impedance of leg (left) 2.1 10.3 21.2 -2.5 -4.0 -4.1 -0.7 -1.7 0.8 -2.8 -2.8 -3.0 -3.3 -3.6 -3.5 -3.8 3.7 -0.3 -4.2 -3.4 -0.2 -3.4 -3.6 -3.5 4.6 -0.5 -3.6 -3.6 -2.0 -3.4 -2.8 -3.4 -3.4 -4.0 3.2 -3.6 -4.1 -2.6 -2.6 -3.3 -3.6 -3.4 -3.1 -3.5 -3.7
Leg predicted mass (left) 1.0 5.4 13.3 1.6 2.8 3.0 0.6 1.1 -0.3 1.9 2.3 2.0 2.2 2.8 2.4 2.6 -2.2 1.1 3.3 2.7 1.7 2.6 2.3 2.9 -2.8 1.3 2.5 2.4 1.3 2.4 1.9 2.2 2.4 3.6 -2.4 2.6 3.0 1.8 1.6 2.7 2.9 1.7 1.9 2.4 2.9
Trunk fat mass 0.1 0.6 7.2 -0.5 0.2 0.5 -0.2 -1.1 0.3 -0.7 1.0 -0.4 0.9 0.1 0.5 -0.6 0.5 -0.3 0.6 -0.1 2.1 0.0 -0.5 0.9 0.3 2.7 0.2 0.2 -0.7 -0.2 -0.4 -0.2 0.3 1.8 0.1 0.8 0.5 -0.1 -0.6 0.4 0.3 -0.4 -0.8 -0.3 1.5
Waist circumference 0.2 0.6 6.0 -0.5 0.5 0.7 -0.4 -1.3 -0.6 -0.8 0.7 -0.6 1.1 0.1 0.5 -0.1 0.4 -1.1 0.7 -0.2 1.1 0.2 -0.2 1.0 -0.1 2.5 0.2 0.2 -0.9 -0.2 -0.2 -0.2 0.3 1.9 0.3 0.8 0.7 -0.3 -0.8 0.4 0.4 -0.6 -0.8 -0.2 1.5
Number of incorrect matches in round 5.1 8.5 14.8 -2.4 -3.8 -3.7 -2.1 -2.1 0.8 -3.0 -3.3 -3.1 -2.9 -3.4 -3.0 -2.9 3.0 0.6 -2.8 -3.0 -0.5 -3.6 -3.1 -2.5 2.9 0.3 -3.5 -3.1 -2.7 -3.1 -3.4 -3.2 -3.1 -3.3 2.9 -3.2 -3.3 -2.8 -2.7 -3.5 -3.5 -1.6 -2.9 -3.3 -2.9
Past tobacco smoking 0.1 0.2 1.7 0.6 0.2 -0.0 -0.8 0.6 0.5 0.3 -0.2 0.6 -0.5 0.2 -0.3 -0.2 0.1 -0.5 -0.4 0.1 0.0 -0.2 0.8 -0.2 1.3 -0.5 0.2 0.0 0.3 0.1 1.1 -0.0 -0.2 -0.3 0.0 -0.1 -0.3 0.0 0.4 0.0 0.1 -0.6 0.2 0.1 -0.4
Alcohol usually taken with meals 0.9 1.4 4.1 -0.1 1.3 1.3 -1.4 0.3 1.3 0.5 1.3 1.3 1.6 1.3 1.1 1.0 -0.8 -1.7 0.9 1.3 -1.9 1.0 0.2 0.8 -0.3 -0.7 1.4 1.0 2.0 1.1 1.1 1.2 1.6 1.3 -1.1 0.9 1.2 1.1 0.6 1.9 1.6 0.4 1.2 1.1 1.1
Nervous feelings 0.3 0.6 3.3 -1.0 -0.6 -0.5 -1.0 -0.9 1.5 -0.6 -0.3 -1.3 -0.3 -0.7 -0.3 -0.6 0.6 0.1 -0.6 -0.9 -0.7 -0.2 -0.7 -0.3 -0.3 0.3 -0.9 -0.7 -1.3 -0.9 -1.2 -0.8 -0.5 -0.5 0.7 -0.2 -0.6 -1.0 -1.8 -0.6 -0.8 -0.9 -0.9 -0.8 -0.2
Frequency of tenseness / restlessness in last 2 weeks 0.8 1.2 3.3 -0.9 -0.9 -0.8 -1.6 -0.9 0.3 -0.8 -1.0 -1.7 -0.7 -1.0 -0.9 -1.0 1.2 -0.2 -0.7 -1.1 -0.5 -0.8 -1.4 -0.7 0.2 0.3 -1.4 -1.3 -1.5 -1.7 -0.2 -1.4 -1.1 -0.8 0.8 -0.8 -1.4 -1.6 -1.8 -0.9 -0.8 -0.7 -1.5 -1.4 -0.7
Hearing difficulty/problems with background noise 0.7 1.1 3.0 -1.3 -1.1 -1.0 -0.7 -1.6 0.3 -1.7 -0.4 -1.0 -0.8 -1.1 -0.8 -1.6 1.4 0.0 -1.6 -1.2 -0.4 -1.0 -1.7 -0.3 0.6 1.2 -1.0 -0.9 -0.7 -0.8 -1.6 -1.1 -0.7 -0.3 1.1 -1.2 -1.3 -0.8 -1.0 -0.7 -0.8 -0.5 -1.1 -1.2 -0.4
Hair/balding pattern: Pattern 2 0.5 0.6 6.1 -1.0 -0.7 -0.9 0.1 -1.0 -1.4 -0.7 -0.8 -0.2 -0.4 -1.1 -0.3 0.3 0.3 -1.6 -1.2 -1.2 -2.5 -0.9 -1.1 -0.1 0.8 0.4 -0.4 -0.4 -0.3 -0.4 -0.2 -0.3 -0.3 -0.2 1.3 -0.8 -0.2 0.4 -0.3 -0.1 -0.2 0.2 -0.7 -0.6 -0.0
Had menopause 0.3 0.4 1.3 0.2 -0.0 0.3 0.4 -0.2 -0.8 -0.0 -0.3 -0.4 -0.2 -0.2 -0.5 -0.7 -0.1 0.1 1.1 0.6 -0.2 -0.3 -0.8 -0.8 -0.1 -0.8 -0.3 -0.5 -0.7 -0.7 -0.4 -0.5 -0.6 -0.9 -1.1 -0.3 -0.9 -0.9 -0.4 -0.9 -0.5 -0.9 -0.4 -0.6 -0.7
Had other major operations 0.1 0.1 0.8 -0.2 -0.2 -0.2 0.1 -0.4 -0.5 -0.4 -0.2 -0.1 0.5 -0.3 0.2 0.4 0.1 -0.9 -0.1 -0.2 -0.8 -0.3 -0.3 0.3 -0.1 0.6 -0.0 0.1 -0.1 0.1 -0.2 -0.1 0.1 0.1 0.3 -0.0 0.0 0.0 0.3 -0.2 0.1 0.4 0.0 -0.5 0.3
Forced vital capacity (FVC) 1.3 5.0 12.0 2.8 2.7 2.4 2.3 2.7 -0.3 2.7 2.3 2.2 1.3 3.0 1.9 2.3 -2.1 3.5 1.9 2.5 1.2 2.6 2.9 1.9 -1.9 -0.1 2.2 2.3 2.1 2.4 2.9 2.0 1.9 2.0 -2.1 2.5 2.0 1.5 2.4 2.2 2.6 1.4 2.6 2.3 1.5
Heel bone mineral density (BMD) T-score, automated (right) 0.5 1.1 2.9 -0.0 -1.5 -1.5 1.2 -0.3 -0.2 -0.9 -0.8 -0.9 -1.7 -1.0 -1.3 -0.3 1.1 0.8 -0.2 -1.1 -0.9 -1.7 -0.3 -0.7 0.8 -0.3 -1.3 -1.3 -0.8 -1.0 -0.9 -1.2 -1.3 -1.4 1.2 -1.2 -1.0 -1.0 -0.1 -1.6 -1.1 -1.3 -1.2 -0.9 -1.3
Ever unenthusiastic/disinterested for a whole week 0.6 0.7 6.8 -1.4 0.0 -0.1 -1.8 -1.6 1.1 -0.4 -0.7 -0.8 0.4 -0.9 0.2 -0.2 0.3 -1.5 -0.4 -0.9 -2.6 -0.3 -0.9 0.5 -0.1 0.2 -0.4 -0.3 -1.1 -0.5 -1.0 -0.3 0.2 0.6 0.7 -0.3 0.0 -0.5 -1.4 0.5 0.0 -0.0 -0.8 -0.2 0.5
Qualifications: None of the above 0.5 1.1 5.8 -1.7 -0.2 -0.0 -0.4 -2.3 -0.7 -1.3 0.7 -0.7 1.8 -0.8 1.3 -0.8 0.1 -1.1 -0.3 -1.4 -0.5 -0.7 -1.7 1.1 0.4 2.4 0.1 0.2 -0.5 -0.4 -1.6 0.2 0.7 1.1 1.2 0.3 0.6 0.7 -0.5 0.2 -0.3 1.9 -1.0 -0.7 2.0
Financial difficulties in last 2 years 0.3 0.5 1.6 -0.7 -0.2 -0.1 -1.2 -1.1 1.1 -0.6 -0.5 -1.0 -0.0 -0.4 -0.1 0.3 0.2 -0.5 -0.1 -0.9 -0.6 -0.7 -0.9 -0.2 0.7 1.2 -0.4 -0.4 -1.1 -0.8 0.1 -0.6 -0.4 0.3 0.4 0.2 -0.5 -0.8 -1.3 -0.5 -0.2 -0.8 -1.1 -1.0 0.2
Mouth/teeth dental problems 0.9 1.4 4.3 0.3 0.8 0.4 -1.7 1.3 2.1 0.3 0.7 1.7 -0.0 0.7 0.8 1.0 -1.5 -1.4 -0.3 0.5 1.1 0.3 1.4 0.5 -1.8 -1.3 1.4 1.2 2.1 1.5 1.6 1.4 1.0 0.4 -0.2 0.8 1.1 1.9 1.5 0.8 0.7 1.4 1.4 1.2 0.3
Heart attack 0.3 0.3 1.6 -0.4 -0.4 -0.2 -0.2 -0.8 0.5 -0.3 -0.0 -0.9 0.2 -0.3 -0.1 -0.6 0.2 0.9 0.2 -0.6 0.0 0.0 -0.3 0.1 -0.3 0.5 -0.7 -0.5 -1.3 -0.8 -1.2 -0.5 -0.4 0.1 0.2 0.3 -0.3 -0.8 -1.2 -0.6 -0.7 -1.0 -0.9 -0.4 0.2
Allergy 0.2 0.4 1.9 -0.8 -0.9 -0.7 -0.7 -0.1 -1.4 0.1 -1.0 0.3 -0.9 -1.0 -0.5 -0.9 0.5 -0.8 -0.4 -0.1 -0.6 -1.0 -0.8 -1.3 0.3 -0.6 -0.3 -0.6 -0.0 -0.5 -0.7 -0.2 -0.4 -1.1 -0.3 -1.1 -0.5 0.2 -0.1 -0.2 -0.2 0.2 -0.7 -0.3 -0.5
Pain all over the body in last month 0.2 0.2 0.9 -0.1 -0.5 -0.3 0.7 -0.1 -0.2 -0.0 -0.1 -0.6 -0.4 -0.4 -0.4 -0.8 0.4 0.6 0.8 -0.0 -0.7 -0.6 -0.1 0.0 -0.1 -0.7 -0.5 -0.6 -0.8 -0.5 -1.0 -0.4 -0.3 0.1 -0.1 -0.5 0.1 -0.7 -0.9 -0.1 -0.3 0.7 -0.5 -0.2 -0.1
Diabetes (self-reported) 0.1 0.2 1.4 -0.1 -0.2 0.0 0.8 -0.6 -1.2 -0.4 0.1 -0.4 0.2 -0.0 0.0 0.4 -0.2 0.8 0.7 0.1 -0.5 -0.3 -0.1 0.1 0.6 0.2 -0.0 0.1 -0.4 0.2 -0.8 -0.0 0.1 0.6 0.0 -0.1 0.3 -0.0 0.0 -0.0 0.1 0.8 0.0 -0.1 0.6
Hayfever/allergic rhinitis (self-reported) 0.4 0.5 1.8 -1.1 -0.9 -0.8 -0.7 -0.4 0.4 -0.5 -0.1 -0.7 -0.2 -0.5 -0.6 0.0 0.5 -0.2 -0.9 -1.0 -1.4 -1.1 -0.6 -0.9 -0.2 -0.5 -0.8 -0.7 -0.3 -0.8 -0.6 -0.5 -0.6 -0.5 0.6 -0.3 -0.9 -0.3 -0.7 -0.5 -0.7 -1.2 -1.0 -0.4 -0.6
Medication: Ramipril 1.4 1.8 3.6 0.1 1.5 1.6 0.9 0.0 0.5 0.5 1.6 1.6 1.9 1.9 1.7 1.4 -1.6 -0.1 0.7 1.1 0.5 1.3 0.9 1.2 -0.5 0.3 1.8 1.4 1.8 1.4 1.2 1.6 1.9 1.7 -1.2 1.8 1.5 1.5 0.8 1.7 1.8 0.4 1.1 1.3 1.6
Medication: Simvastatin 0.6 0.9 3.3 1.3 1.1 1.2 1.2 0.8 0.2 1.0 1.2 0.7 1.8 1.1 1.0 0.6 -0.7 1.0 0.9 0.9 1.0 1.4 1.3 0.5 -0.7 0.1 0.9 1.0 0.5 0.7 1.0 0.9 0.8 0.5 -1.2 1.2 1.1 0.3 1.5 0.4 0.7 0.5 0.9 1.0 0.8
Fluid intelligence score 0.8 1.7 5.8 1.0 -1.2 -1.1 1.2 0.4 0.5 -0.3 -0.9 -1.1 -1.6 -0.6 -1.7 0.5 1.6 2.4 -0.2 -0.4 1.9 -0.8 -0.4 -1.5 0.7 0.1 -1.6 -1.7 -1.8 -1.8 -0.2 -1.7 -1.7 -1.6 0.3 -1.4 -1.3 -2.0 -0.0 -1.8 -1.4 -1.2 -1.5 -1.0 -1.8
Illnesses of siblings 0.8 1.2 6.2 -2.0 0.3 0.4 -2.5 -1.2 -1.4 -0.6 0.3 0.4 0.6 -0.0 1.3 -0.3 -0.8 -1.7 -0.4 -0.0 -1.1 0.7 -0.7 1.0 -1.5 0.1 1.1 0.8 1.3 0.9 -0.1 1.1 1.5 1.5 0.1 0.2 1.6 1.9 0.1 1.5 1.1 1.2 0.3 0.8 1.5
Neuroticism score 0.6 1.2 3.0 -0.2 -1.2 -1.1 -0.9 -0.5 0.9 -0.7 -0.7 -1.7 -0.9 -0.9 -1.2 -0.5 1.3 0.9 -0.7 -1.1 -0.2 -1.1 -0.7 -0.8 0.7 0.4 -1.5 -1.2 -1.7 -1.3 -0.7 -1.5 -1.4 -1.0 1.1 -0.9 -1.3 -1.7 -1.6 -1.3 -1.1 -0.7 -1.1 -1.5 -0.9
Weight 0.4 2.0 7.9 0.6 1.6 1.9 0.1 0.1 -0.1 0.8 1.7 1.0 1.5 1.4 1.5 1.0 -0.9 0.1 2.3 1.6 1.9 1.3 0.8 1.9 -1.5 1.8 1.6 1.3 0.5 1.2 0.9 1.1 1.4 2.8 -1.4 1.6 1.9 1.0 0.6 1.7 1.7 0.5 0.6 1.2 2.3
Impedance of arm (right) 0.5 2.5 7.1 -0.2 -1.8 -1.8 0.2 0.5 0.8 -0.5 -1.3 -1.1 -2.1 -0.6 -2.1 -1.4 1.6 1.8 -1.2 -0.8 2.4 -1.2 -0.9 -2.1 2.5 -1.4 -1.7 -1.8 -0.6 -1.5 -0.7 -1.6 -2.0 -2.4 0.6 -1.5 -2.2 -1.5 -0.9 -1.7 -1.6 -2.7 -0.9 -1.2 -2.7
Arm fat percentage (right) 0.1 0.5 5.9 0.2 0.6 0.8 -0.3 -0.3 0.2 0.1 0.7 -0.2 0.8 0.5 0.4 -0.2 0.1 -0.1 1.1 0.2 2.4 0.3 0.2 0.6 -0.3 1.5 0.4 0.2 -0.6 -0.2 0.3 -0.0 0.2 1.5 -0.4 1.0 0.7 -0.3 -0.3 0.4 0.3 -0.7 -0.6 0.2 1.1
Trunk fat-free mass 0.8 4.6 9.3 1.3 2.5 2.7 0.3 1.1 -1.0 1.8 2.1 2.2 1.9 2.3 2.3 2.8 -2.2 0.5 2.9 2.5 0.6 2.2 1.8 2.7 -2.8 0.9 2.5 2.2 1.6 2.3 1.9 2.2 2.3 3.0 -2.3 2.2 2.7 2.1 1.6 2.5 2.8 1.7 1.8 2.2 2.6
Hip circumference 0.2 1.0 4.4 0.6 1.2 1.4 0.6 0.2 0.1 0.4 1.3 0.9 1.1 1.1 0.9 0.7 -0.6 0.3 1.7 1.1 2.1 0.6 0.7 1.1 -1.2 1.7 1.1 0.9 0.3 0.7 0.7 0.7 0.8 1.8 -0.9 1.2 1.2 0.6 0.5 0.9 1.1 0.1 0.3 0.7 1.4
Time employed in main current job 0.4 0.4 5.9 1.0 -0.1 -0.2 1.6 0.5 0.3 -0.2 0.4 -0.2 0.4 0.0 -0.2 0.1 0.4 2.4 -0.3 -0.3 0.3 -0.2 0.5 -0.3 -0.1 1.2 -0.5 0.1 -0.2 -0.3 -0.1 -0.3 -0.5 -1.1 0.6 0.3 -0.9 -0.7 0.6 -1.0 -0.8 0.2 0.1 -0.3 -0.4
Alcohol intake versus 10 years previously 2.5 3.8 7.1 -1.4 -2.1 -2.1 0.8 -1.6 -0.2 -1.7 -1.8 -2.4 -1.8 -2.2 -1.9 -1.5 2.7 -0.3 -1.5 -2.1 -1.0 -2.0 -2.4 -1.6 2.2 1.2 -2.4 -2.2 -2.5 -2.4 -2.4 -2.5 -2.0 -1.2 2.1 -2.2 -1.9 -2.4 -2.4 -1.6 -1.9 -0.6 -2.4 -2.4 -1.3
Father’s age at death 0.3 0.4 2.5 -0.3 0.6 0.7 -0.0 -0.8 -0.4 -0.4 0.8 -0.1 1.6 0.0 0.8 -0.1 -0.6 -0.8 0.1 0.5 -1.0 -0.0 0.2 0.8 -0.5 0.8 0.5 0.9 0.5 0.6 -0.2 0.5 0.8 0.9 -0.1 1.2 0.5 0.3 -0.1 0.6 0.3 0.4 0.8 -0.0 1.1
Worrier / anxious feelings 0.3 0.5 2.6 -0.6 -0.7 -0.5 -0.5 -0.5 1.4 -0.5 0.0 -0.8 -0.8 -0.6 -0.8 -0.7 0.9 0.1 -0.5 -0.3 -0.4 -0.5 -0.7 -0.4 0.9 -0.1 -0.7 -0.9 -0.7 -0.7 -0.2 -0.7 -0.7 -0.2 0.2 -0.5 -0.9 -0.8 -1.5 -0.3 -0.3 -1.6 -0.8 -0.6 -0.4
Frequency of tiredness / lethargy in last 2 weeks 0.2 0.3 3.4 0.0 0.3 0.6 -0.3 0.3 0.2 0.9 -0.4 -0.0 0.6 0.4 0.2 0.9 -0.1 0.8 1.8 0.8 0.8 0.6 -0.0 0.1 -0.2 0.2 0.3 -0.2 -0.1 0.1 0.7 0.1 0.2 0.9 -1.3 -0.0 0.5 -0.2 -0.6 0.8 1.0 0.2 -0.2 0.1 0.5
Falls in the last year 0.2 0.2 1.3 0.1 -0.4 -0.2 0.1 -0.3 -0.0 -0.2 -0.0 -0.4 -0.5 -0.3 -0.8 -0.0 0.3 1.1 1.0 0.1 1.1 -0.0 0.0 -0.6 -0.0 -0.0 -0.3 -0.5 -0.6 -0.1 -0.3 -0.4 -0.7 -0.1 -0.4 -0.5 -0.4 -0.5 -0.0 -0.5 -0.1 -1.1 -0.5 -0.6 -0.1
Hair/balding pattern: Pattern 3 0.1 0.1 1.1 0.2 0.1 0.1 -0.3 0.1 -0.5 -0.4 0.1 -0.1 0.4 -0.3 0.2 0.0 -0.1 1.0 -0.2 0.0 0.1 -0.3 0.1 0.5 -0.0 -0.1 0.2 0.2 0.7 0.2 -0.2 0.1 0.2 -0.4 0.2 0.2 -0.3 -0.1 0.3 -0.2 -0.4 -0.2 0.5 -0.1 -0.1
Number of live births 1.0 1.3 4.7 0.5 1.3 1.3 -0.2 0.5 0.6 0.8 1.2 1.4 1.0 1.3 1.4 0.4 -1.3 0.3 0.9 0.7 0.1 0.5 0.6 1.3 -1.5 0.4 1.5 1.3 1.6 1.2 0.5 1.5 1.6 1.2 -0.9 1.1 1.1 1.6 1.2 1.5 1.4 2.2 1.1 1.6 1.4
Forced expiratory volume in 1-second (FEV1) 0.9 3.0 5.7 1.8 1.9 1.6 1.6 2.0 0.2 1.7 1.9 1.9 1.3 2.2 1.6 2.0 -1.4 1.7 0.7 1.5 0.9 2.0 2.0 1.6 -1.0 0.6 1.9 1.9 2.3 2.1 2.2 1.7 1.6 2.0 -1.0 1.8 1.8 1.8 2.0 2.2 2.4 1.6 2.1 1.8 1.4
Pulse rate 0.1 0.2 1.2 0.3 0.5 0.3 -0.2 -0.1 0.6 -0.0 0.2 0.1 -0.2 0.2 0.6 -0.0 -0.4 -1.1 -0.2 0.1 0.9 0.4 -0.0 1.0 0.6 -0.1 0.3 0.5 0.6 0.5 -0.2 0.3 0.4 0.2 0.3 0.6 0.1 0.2 0.3 0.2 0.1 -0.0 0.7 -0.0 0.4
Happiness 0.2 0.3 1.8 0.3 0.4 0.6 0.1 -0.2 0.4 0.1 0.5 -0.1 1.4 0.7 0.7 1.2 -0.1 0.9 0.3 0.0 0.4 0.8 0.3 0.6 -0.9 1.1 0.2 0.4 0.1 0.3 -0.0 0.3 0.6 0.4 -0.3 0.6 0.3 -0.1 0.5 0.0 0.5 -0.0 0.1 0.1 0.6
Noisy workplace 1.1 1.3 5.2 0.9 1.6 1.9 -0.3 0.7 1.1 1.9 1.5 0.6 1.1 1.5 1.1 0.5 -1.2 0.1 2.1 1.7 1.1 1.0 0.9 0.7 -1.0 -1.2 1.0 0.8 0.1 0.4 1.1 0.8 1.1 1.1 -2.3 1.0 1.4 0.1 -0.1 1.4 1.0 1.1 0.6 0.9 1.1
Qualifications: A levels/AS levels or equivalent 1.0 2.2 5.3 0.1 -1.4 -1.5 -0.0 0.5 0.3 0.2 -1.7 -1.4 -1.9 -1.1 -2.2 -0.8 1.7 1.8 -0.8 -0.7 1.0 -0.9 -0.8 -2.3 1.0 -1.8 -1.7 -1.9 -1.5 -1.9 -0.2 -1.7 -2.0 -2.0 0.4 -2.0 -1.9 -1.8 -1.2 -1.4 -1.4 -2.0 -1.7 -1.2 -2.3
Serious illness, injury or assault of a close relative in last 2 years 3.7 4.2 11.4 0.3 -1.9 -1.8 -0.4 -0.2 -0.2 -0.9 -2.1 -2.1 -2.6 -1.7 -2.9 -0.4 2.7 1.9 -1.0 -1.4 -0.2 -1.5 -1.1 -2.5 2.1 -1.0 -2.6 -2.6 -3.2 -2.6 -0.5 -2.9 -3.0 -2.2 1.0 -2.4 -2.4 -3.4 -1.8 -2.7 -2.2 -2.2 -2.3 -2.2 -2.8
Mouth/teeth dental problems: Dentures 0.3 0.5 3.4 0.4 0.3 0.4 0.9 -0.8 -1.9 -0.0 0.5 -0.6 1.2 0.3 0.1 0.1 0.5 1.5 0.5 -0.1 -1.3 0.9 -0.2 0.6 0.6 1.6 -0.5 -0.1 -1.2 -0.6 0.0 -0.4 -0.2 0.4 0.1 0.7 0.0 -0.9 -0.1 -0.4 -0.2 -0.8 -0.5 -0.3 0.6
Asthma 0.1 0.2 1.4 0.3 0.4 0.5 -0.1 0.2 1.2 0.4 0.4 -0.4 0.2 0.6 0.4 0.5 -0.5 0.2 0.9 0.5 -0.8 0.2 0.1 0.6 -0.5 -0.1 0.3 0.4 0.0 0.3 -0.6 0.2 0.3 0.5 -0.5 0.5 0.0 0.0 -0.1 0.3 0.1 -0.2 0.4 0.1 0.4
Medication: Ibuprofen (e.g. Nurofen) 1.1 1.4 8.3 -1.3 -0.7 -0.8 -2.1 -2.1 0.9 -1.6 -1.3 -1.1 -0.3 -1.6 -0.4 -0.8 0.9 -1.3 -1.1 -1.5 -2.9 -0.9 -1.8 -0.0 1.4 0.7 -0.9 -0.8 -1.5 -0.9 -0.6 -0.9 -0.5 -0.1 1.7 -0.6 -0.7 -0.7 -1.6 -0.7 -0.8 -1.0 -1.1 -1.5 0.1
Medication: Cholesterol lowering 0.5 0.8 4.7 -0.3 1.0 1.3 -0.7 -0.5 0.7 0.2 1.2 0.3 2.2 0.7 1.5 0.4 -0.7 -0.4 0.2 0.6 -0.3 1.3 0.2 0.9 -0.9 0.3 0.9 1.1 0.6 0.6 -0.1 1.0 1.3 1.1 -0.8 1.4 1.0 0.6 0.4 0.9 0.8 0.7 0.6 0.9 1.4
Depression (self-reported) 0.6 0.7 3.0 -1.7 -0.4 -0.2 -1.2 -1.7 0.9 -1.0 -0.4 -0.9 0.5 -1.3 -0.0 -0.8 0.8 -0.7 -0.5 -0.9 -1.2 -0.9 -1.4 0.2 0.3 0.9 -0.7 -0.8 -1.2 -0.9 -0.2 -0.8 -0.2 0.1 0.4 -0.2 -0.1 -0.9 -1.7 -0.3 -0.3 -0.9 -1.5 -0.8 0.2
Medication: Lansoprazole 0.4 0.5 1.7 -0.7 -0.6 -0.5 0.1 -0.5 1.1 -0.3 -1.1 -0.9 -0.5 -0.5 -0.4 -1.3 0.4 1.2 0.1 -0.3 -0.0 -0.5 -0.9 -0.5 0.1 -0.7 -0.5 -0.7 -0.9 -0.8 -1.1 -0.6 -0.4 -0.4 -0.1 -0.9 -0.3 -0.6 -1.2 -0.2 -0.7 0.5 -0.7 -0.4 -0.4
Prospective memory result 0.5 0.6 2.7 0.5 1.0 1.1 0.7 0.3 -0.1 1.0 1.3 0.7 1.6 0.6 1.0 -0.0 -1.0 0.2 1.2 0.7 0.5 1.0 0.6 0.7 -0.9 -0.4 0.7 0.9 0.2 0.6 0.7 0.8 0.7 0.6 -1.1 1.2 0.7 0.3 0.2 0.7 0.4 0.3 0.7 0.8 0.8
Lung cancer (father) 0.8 1.0 2.8 0.1 -0.9 -1.1 1.2 0.1 -1.1 -0.9 -0.9 -1.1 -0.7 -0.8 -0.9 0.3 0.7 0.8 -1.2 -1.1 0.1 -0.9 -0.3 -1.1 1.6 1.2 -1.2 -0.8 -0.8 -0.9 0.8 -1.2 -1.2 -1.1 1.3 -0.4 -1.7 -1.3 -0.8 -1.4 -0.8 -0.3 -0.6 -1.5 -1.1
Illnesses of mother 0.7 0.8 2.8 0.3 -0.7 -0.7 1.1 0.0 0.9 0.2 -1.0 -0.9 -1.2 -1.1 -0.9 -0.4 0.2 0.2 -0.1 -0.6 -0.3 -0.7 -0.5 -0.6 -0.3 -0.3 -1.2 -0.9 -1.7 -1.2 -0.5 -1.0 -1.2 -1.6 0.4 -0.9 -1.1 -1.4 -0.5 -1.5 -1.3 0.7 -1.0 -1.1 -1.2
Forced expiratory volume in 1-second (FEV1), Best measure 1.1 3.4 5.7 2.0 2.0 1.7 1.7 2.4 0.2 1.9 1.7 2.1 1.3 2.4 1.5 2.2 -1.6 2.0 1.1 1.8 0.6 1.9 2.2 1.3 -1.3 0.1 2.0 1.9 2.4 2.2 2.4 1.8 1.7 1.9 -1.5 1.7 1.8 1.8 1.9 2.2 2.4 2.1 2.2 1.9 1.2
Pulse wave Arterial Stiffness index 0.8 0.9 3.6 0.0 1.4 1.4 -0.2 0.1 -0.3 0.9 0.7 1.1 1.3 1.1 1.3 0.9 -1.2 -1.3 0.7 0.9 -0.5 0.6 0.4 0.9 -1.9 0.1 1.3 1.2 0.7 0.8 0.7 1.2 1.2 0.6 -1.0 1.3 0.8 0.9 0.8 0.9 0.9 0.8 0.9 0.8 1.2
Impedance of arm (left) 0.9 4.2 12.0 -0.9 -2.6 -2.7 0.1 -0.2 0.9 -1.3 -2.1 -1.8 -2.4 -1.5 -2.6 -2.2 2.2 1.6 -2.2 -1.6 1.6 -1.8 -1.7 -2.6 3.5 -1.2 -2.3 -2.3 -1.0 -2.0 -1.7 -2.1 -2.4 -2.8 1.4 -2.3 -2.8 -1.9 -1.3 -2.1 -2.2 -2.7 -1.5 -1.8 -3.0
Arm fat mass (right) 0.3 1.3 5.7 0.4 1.4 1.6 -0.1 -0.2 0.0 0.5 1.4 0.6 1.5 1.1 1.2 0.6 -0.5 -0.3 1.6 1.0 2.1 1.1 0.6 1.5 -0.9 2.0 1.2 1.0 0.1 0.7 0.7 0.7 1.1 2.4 -0.9 1.6 1.5 0.5 0.3 1.3 1.2 0.2 0.2 0.8 2.0
Trunk predicted mass 0.8 4.7 9.6 1.2 2.5 2.7 0.3 1.0 -1.1 1.8 2.1 2.2 2.0 2.3 2.4 2.8 -2.2 0.3 2.9 2.6 0.6 2.2 1.8 2.7 -2.8 1.0 2.5 2.2 1.6 2.3 1.9 2.2 2.4 3.1 -2.3 2.3 2.7 2.1 1.5 2.5 2.8 1.7 1.8 2.2 2.6
Standing height 0.1 1.0 3.3 0.2 0.5 0.8 0.2 0.6 0.2 0.5 1.0 1.1 0.4 1.3 0.7 1.5 -0.5 1.8 1.2 1.6 1.8 1.2 0.2 1.3 -0.1 0.7 0.9 0.7 1.4 1.2 0.6 0.9 0.9 1.4 -1.3 0.7 0.6 1.2 0.7 1.3 1.6 -0.3 0.8 0.8 0.9
Length of working week for main job 0.6 0.7 5.1 1.3 -0.3 -0.3 0.5 1.3 1.8 1.1 -0.1 0.2 -1.0 0.4 -0.7 1.5 0.1 2.2 1.1 0.1 0.3 -0.6 0.7 -0.8 -0.3 -0.9 -0.3 -0.2 -0.6 -0.3 0.7 -0.4 -0.9 -1.2 -0.2 -0.6 -0.5 -0.5 1.4 -0.9 -0.6 0.0 -0.2 -0.4 -0.8
Exposure to tobacco smoke at home 2.1 2.4 6.9 -2.3 -1.6 -1.7 -1.7 -1.7 1.2 -1.7 -2.6 -1.4 -1.0 -1.5 -1.0 -2.0 1.9 -2.6 -2.4 -1.9 -1.1 -0.5 -2.0 -0.5 0.9 1.1 -1.3 -1.6 -0.5 -1.4 -1.7 -1.3 -1.0 -0.4 2.0 -1.2 -1.5 -0.9 -1.7 -0.2 -0.8 -2.1 -1.7 -1.1 -0.6
Breastfed as a baby 0.5 0.6 2.0 -0.1 0.7 0.6 -0.0 0.4 1.1 0.4 0.2 1.2 0.7 1.0 0.5 1.1 -0.8 -1.1 -0.2 0.7 0.0 0.9 0.4 0.5 -1.4 1.0 1.0 0.9 1.4 0.7 0.1 0.9 0.8 0.2 -0.7 0.5 0.1 1.0 0.4 0.9 0.9 0.4 0.8 0.5 0.4
Tense / ‘highly strung’ 0.2 0.4 6.4 -1.0 -0.2 0.1 -2.5 -0.8 -0.1 -0.2 -0.4 -0.4 0.3 -0.2 0.3 0.8 -0.0 -0.3 0.6 -0.0 -1.1 0.1 -0.8 -0.3 -1.0 -0.4 -0.2 -0.4 -0.2 -0.4 -0.4 -0.1 0.2 0.1 -0.5 0.0 0.0 -0.3 -0.9 0.1 0.2 -0.5 -0.7 -0.2 0.2
Seen doctor (GP) for nerves, anxiety, tension or depression 0.2 0.3 2.2 -0.5 -0.3 -0.1 -1.0 -0.4 1.5 -0.3 -0.8 0.3 -0.6 -0.3 -0.4 0.3 0.6 0.6 -0.3 0.2 -0.6 1.4 -0.8 -0.2 0.4 -0.3 0.0 -0.5 -0.0 -0.2 0.3 -0.3 -0.1 0.1 -0.4 -0.5 0.1 -0.1 -0.6 0.3 0.5 -1.3 -0.4 -0.2 -0.2
Hair/balding pattern: Pattern 4 0.7 1.7 6.9 -1.0 -1.4 -1.4 -0.5 -0.8 0.5 -1.2 -1.4 -1.4 -0.4 -1.4 -1.0 -2.6 1.1 1.0 -1.4 -1.3 1.1 -1.8 -1.1 -1.4 0.4 1.2 -1.4 -1.0 -1.6 -1.2 -2.3 -1.2 -1.1 -1.2 1.4 -1.3 -1.4 -0.9 -1.5 -1.5 -1.4 0.4 -1.1 -1.3 -1.0
Birth weight of first child 0.3 0.5 2.0 0.9 -0.4 -0.6 0.3 0.8 -1.4 0.2 -0.7 -0.3 -1.2 0.6 -0.8 -1.0 0.4 1.0 -0.8 0.1 -0.5 -0.8 0.3 -0.6 0.8 -0.5 -0.7 -0.6 -0.2 -0.4 0.1 -0.6 -0.8 -0.9 0.4 -0.4 -0.9 -0.8 0.1 -0.6 -0.4 -0.5 0.2 -0.4 -1.1
Peak expiratory flow (PEF) 2.0 4.7 11.3 0.0 2.0 1.7 1.2 0.2 0.1 0.2 2.3 2.2 2.8 1.9 3.0 1.7 -1.8 -1.5 -0.4 0.5 -0.3 1.9 1.2 2.6 -0.8 2.7 2.7 2.7 3.1 2.7 1.6 2.6 3.0 3.1 0.0 2.1 2.9 3.4 1.9 2.9 3.0 3.0 2.2 1.9 3.0
Pulse wave reflection index 0.5 0.6 5.0 -0.2 0.9 1.0 -0.2 0.1 -1.1 0.7 0.2 0.5 0.9 0.5 0.8 0.8 -1.2 -0.7 0.9 0.5 -1.6 0.1 0.2 0.4 -2.2 0.1 0.7 0.7 -0.1 0.2 0.4 0.7 0.7 0.3 -0.9 0.6 0.7 0.4 0.0 0.4 0.5 1.1 0.2 0.6 0.7
Ever highly irritable/argumentative for 2 days 1.6 1.9 6.7 0.9 1.6 1.8 -1.1 0.6 0.8 1.8 1.9 1.1 1.9 1.2 1.4 1.6 -1.3 0.1 2.5 1.3 -0.3 1.1 1.0 1.0 -2.6 -1.0 1.2 1.0 0.6 1.0 2.2 1.2 1.4 1.2 -1.9 1.4 1.8 0.7 1.3 1.1 1.4 -0.1 0.4 1.4 1.4
Loud music exposure frequency 0.1 0.2 0.8 0.4 -0.2 -0.5 -0.7 0.1 -0.1 0.1 -0.6 -0.4 -0.6 -0.1 -0.4 0.4 -0.0 0.2 -0.4 -0.2 0.0 -0.7 0.3 0.2 0.9 -0.0 -0.4 -0.2 -0.0 -0.0 0.5 -0.4 -0.4 -0.1 0.8 -0.1 -0.0 -0.6 0.3 -0.1 -0.3 -0.6 0.3 -0.4 -0.4
Qualifications: O levels/GCSEs or equivalent 1.1 1.7 6.2 0.6 -1.1 -1.4 1.4 0.8 0.4 -0.2 -1.8 -0.8 -2.5 -0.6 -2.2 -0.7 1.1 1.8 -1.1 -0.4 0.3 -0.5 0.1 -2.0 1.1 -1.6 -1.4 -1.4 -0.8 -1.1 -0.4 -1.4 -1.8 -1.7 0.5 -1.4 -1.8 -1.7 -0.8 -1.3 -1.1 -2.0 -0.6 -0.8 -2.5
Mouth/teeth dental problems: Bleeding gums 0.3 0.3 1.6 -0.6 -0.2 -0.0 -0.3 -0.9 -0.9 -0.1 -0.6 -0.9 0.4 -0.7 0.0 -0.6 0.4 -0.3 0.5 -0.2 -1.0 -0.7 -0.9 -0.1 0.5 0.0 -0.5 -0.6 -0.7 -0.8 -0.9 -0.5 -0.2 -0.2 -0.0 -0.4 -0.5 -0.9 -1.3 0.1 -0.1 -0.4 -0.6 -0.7 0.1
Blood clot in the leg (DVT) 0.1 0.1 1.1 0.2 0.2 0.1 0.0 -0.1 0.7 -0.4 -0.0 0.3 -0.1 0.7 0.2 0.4 -0.2 0.5 -0.0 -0.1 -1.0 -0.0 0.3 0.0 0.2 0.4 0.1 0.3 -0.1 0.1 0.5 -0.0 0.0 -0.2 0.3 0.2 -0.0 0.1 1.1 -0.5 -0.2 0.5 0.3 -0.1 -0.1
Medication: Paracetamol 0.9 1.4 4.5 -0.7 -0.8 -0.9 -0.5 -1.3 0.2 -0.7 -0.5 -2.0 -0.4 -1.0 -0.7 -1.6 1.1 0.6 -0.6 -1.1 -1.8 -1.7 -1.4 -0.0 1.5 1.4 -1.4 -1.0 -2.1 -1.1 -1.8 -1.4 -1.0 -0.6 1.4 -1.1 -1.4 -1.7 -1.5 -1.0 -1.0 -0.5 -1.0 -1.7 -0.4
Headache pain in last month 2.4 4.2 8.2 -1.6 -2.3 -2.3 -0.5 -1.0 1.1 -1.3 -2.8 -2.3 -2.8 -2.0 -2.3 -1.5 2.5 0.4 -1.7 -1.8 -0.9 -2.2 -2.4 -2.4 2.9 0.1 -2.2 -2.5 -2.1 -2.4 -1.7 -2.4 -2.2 -1.8 1.7 -2.8 -2.2 -2.0 -2.7 -1.5 -2.0 -1.3 -2.2 -2.6 -1.9
Medication for cholesterol, blood pressure or diabetes 0.6 0.9 3.0 0.5 -0.9 -1.2 0.7 0.7 -0.5 0.2 -0.8 -0.6 -1.7 -0.9 -1.5 -0.3 0.8 0.8 -0.3 -0.6 1.0 -1.4 0.0 -0.9 0.5 -0.8 -1.1 -1.1 -1.0 -0.7 0.0 -1.1 -1.5 -1.5 0.9 -1.3 -1.1 -1.0 -0.6 -1.2 -1.1 -0.8 -0.5 -0.9 -1.6
Glaucoma (self-reported) 0.2 0.3 2.3 0.6 0.0 0.3 0.0 0.7 -0.3 0.8 0.1 0.1 -0.6 0.7 -0.2 0.9 -0.5 -0.2 1.4 0.9 1.5 0.2 0.7 0.2 -0.4 -0.8 0.0 -0.1 -0.1 0.1 0.0 0.0 -0.2 0.2 -1.2 0.0 0.3 -0.1 -0.0 0.0 0.3 0.2 0.1 0.5 -0.3
Gout (self-reported) 1.8 2.5 5.2 -0.4 -1.8 -1.6 0.6 -0.3 -1.3 -0.7 -1.6 -1.6 -1.8 -1.6 -1.7 -1.5 1.6 1.6 -0.7 -1.1 -0.3 -1.5 -1.4 -1.4 1.6 -0.6 -2.1 -1.7 -2.0 -2.1 -1.9 -1.8 -1.8 -2.2 1.0 -1.3 -2.1 -2.3 -1.1 -2.2 -2.2 -1.3 -1.7 -1.6 -1.8
Hypothyroidism/myxoedema (self-reported) 0.5 0.9 4.2 0.5 1.2 1.1 -0.7 0.7 1.0 1.4 0.9 0.7 2.0 0.9 1.2 1.5 -0.6 0.8 0.9 0.7 -0.2 2.0 0.9 1.2 -0.6 -0.1 0.8 1.0 0.3 0.5 0.5 1.0 1.0 0.8 -0.7 1.1 1.0 0.5 0.8 1.0 0.3 1.1 0.5 1.2 1.1
Medication: Amlodipine 0.7 1.0 5.5 -1.5 -1.0 -0.7 -1.6 -2.0 -2.2 -1.7 -0.7 -0.8 0.7 -0.8 -0.2 -0.9 0.7 -0.2 -0.6 -1.1 -2.3 -0.6 -1.4 -0.4 0.6 0.9 -0.6 -0.7 -0.9 -0.9 -1.5 -0.5 -0.1 0.5 0.6 -0.6 0.1 -0.4 -1.3 -0.3 -0.5 -0.1 -1.3 -0.6 0.4
Medication: Ventolin 100micrograms inhaler 0.4 0.6 4.3 1.0 0.0 0.1 0.2 0.8 0.0 0.8 -0.2 -0.7 -0.6 0.4 -0.6 0.5 0.2 2.1 1.5 0.3 -0.6 -0.3 0.4 -0.9 -0.1 -1.3 -0.4 -0.8 -1.0 -0.7 0.2 -0.6 -0.7 -0.7 -1.0 -0.3 -0.1 -1.2 -0.1 -0.7 -0.4 -1.5 -0.8 -0.1 -0.7
Birth weight 0.3 0.6 2.2 -1.0 0.3 0.4 -1.0 -0.7 1.5 -0.5 0.3 0.7 0.7 0.7 0.9 0.5 -0.4 -0.6 -0.3 0.1 0.1 0.8 -0.5 0.3 0.4 1.5 0.7 0.7 1.2 0.6 0.2 0.8 1.0 1.4 -0.4 0.5 0.7 1.2 0.1 1.2 1.1 0.9 0.4 0.4 1.2
Chronic bronchitis/emphysema (mother) 0.7 0.8 2.7 0.8 0.8 0.8 0.0 0.6 -0.6 0.6 1.3 0.8 0.4 0.6 0.7 0.7 -1.2 0.6 1.3 0.9 1.4 0.5 1.3 1.7 -0.9 -1.0 0.9 1.0 0.8 1.3 0.7 1.1 0.9 0.7 -0.6 0.9 1.3 0.9 0.6 0.7 0.8 0.1 1.4 1.3 0.6
High blood pressure (siblings) 0.5 0.7 5.4 2.0 0.3 0.2 2.3 1.2 1.2 0.9 0.8 0.3 0.1 0.6 -0.5 1.1 0.4 1.1 0.5 0.5 1.8 0.7 1.0 -0.1 0.6 -0.0 -0.3 -0.0 -0.4 -0.0 0.5 -0.3 -0.6 -0.6 -0.5 0.3 -0.6 -0.9 0.9 -0.6 -0.2 -0.8 0.3 0.0 -0.7
Forced vital capacity (FVC), Best measure 0.9 3.3 10.0 2.0 2.1 2.0 1.9 2.1 -0.1 2.1 1.8 1.8 1.3 2.6 1.5 1.6 -1.6 3.2 1.6 2.0 0.8 2.1 2.1 1.1 -1.8 0.1 1.8 1.8 1.8 1.9 2.1 1.6 1.6 1.8 -1.8 1.8 1.6 1.3 1.5 2.0 2.3 1.6 1.9 1.8 1.2
Body fat percentage 0.3 1.0 5.6 -0.9 -0.7 -0.4 -0.3 -1.4 0.4 -1.2 0.2 -1.2 0.2 -0.8 -0.4 -1.7 1.4 -0.5 -0.2 -1.0 1.9 -0.8 -1.1 -0.1 1.0 2.4 -0.7 -0.7 -1.4 -1.2 -1.0 -1.1 -0.6 0.7 0.8 0.0 -0.4 -1.0 -1.2 -0.5 -0.7 -1.2 -1.6 -1.1 0.6
Leg fat percentage (right) 0.2 0.6 3.1 -0.7 -0.6 -0.4 -0.0 -0.7 0.9 -0.5 0.3 -0.8 -0.4 -0.8 -0.5 -1.8 1.1 -0.8 -0.0 -0.7 1.4 -0.9 -1.0 -0.3 0.4 0.9 -0.6 -0.8 -1.0 -1.2 -0.9 -0.9 -0.6 0.1 0.5 -0.5 -0.3 -0.8 -1.0 -0.3 -0.7 -0.6 -1.5 -0.8 0.1
Arm fat-free mass (right) 0.6 3.2 9.8 0.6 2.0 2.3 -0.1 0.0 -0.6 1.0 2.0 1.5 2.0 1.7 2.2 1.9 -1.6 -0.3 2.4 1.9 0.3 1.7 1.1 2.4 -2.2 1.8 2.0 1.8 1.0 1.8 1.2 1.7 2.1 3.1 -1.6 1.9 2.4 1.7 1.0 2.2 2.4 1.7 1.1 1.5 2.8
Exposure to tobacco smoke outside home 0.2 0.3 3.1 -0.1 0.1 -0.0 -1.1 -0.9 -1.8 -0.6 0.5 0.1 0.5 0.2 0.3 0.6 0.1 0.8 0.3 -0.6 -0.4 -0.0 -0.2 0.6 -0.3 0.9 0.2 0.1 0.1 0.1 0.3 0.1 0.3 0.7 0.8 0.3 0.7 0.2 0.3 0.2 0.2 -0.4 -0.2 -0.1 0.8
Comparative body size at age 10 0.6 1.6 6.3 -0.2 1.6 1.7 -0.8 -0.1 0.4 0.6 1.0 0.6 0.9 1.2 1.5 -0.0 -1.3 -0.6 1.2 1.1 -0.4 1.5 0.6 1.8 -1.9 0.9 1.4 1.3 0.9 1.2 0.4 1.2 1.5 2.5 -1.2 1.0 1.7 1.2 -0.1 2.1 1.6 1.6 0.8 1.1 2.0
Number of full brothers 0.3 0.3 3.8 -0.2 0.1 -0.1 -1.1 -0.1 0.8 -0.0 0.2 -0.2 0.0 0.1 0.1 0.9 -0.0 0.1 -0.6 -0.6 -0.4 0.6 -0.1 0.4 0.3 1.2 0.3 0.3 0.3 0.1 -0.2 0.1 0.1 1.2 0.7 -0.0 0.3 0.5 0.1 0.9 0.2 2.0 -0.1 -0.2 0.9
Worry too long after embarrassment 0.8 1.3 4.0 -0.7 -1.1 -1.0 -1.1 -0.6 -0.3 -0.6 -1.3 -1.5 -1.3 -1.1 -1.2 -0.4 0.7 -0.1 0.1 -0.6 -2.0 -1.6 -1.0 -0.9 0.1 -0.8 -1.2 -1.3 -1.4 -1.2 -1.1 -1.2 -1.3 -1.5 0.4 -1.3 -1.5 -1.4 -1.5 -1.3 -1.2 -1.0 -1.0 -1.4 -1.2
Seen a psychiatrist for nerves, anxiety, tension or depression 1.6 2.0 5.2 -1.0 -1.0 -1.0 -0.6 -1.7 -0.4 -1.3 -1.2 -2.1 -0.7 -1.8 -1.2 -1.3 1.3 -0.3 -0.8 -1.6 -1.2 -0.8 -1.6 -0.8 0.8 0.8 -1.7 -1.5 -2.3 -1.8 -1.2 -1.8 -1.4 -0.9 1.1 -0.7 -1.5 -2.2 -2.2 -1.6 -1.4 -2.0 -2.1 -1.8 -0.9
Wheeze or whistling in the chest in last year 0.2 0.4 1.4 0.9 0.5 0.4 1.0 0.9 1.0 0.9 0.5 -0.1 0.2 1.2 0.1 1.1 -0.3 1.1 0.8 0.3 0.3 0.8 0.8 0.6 -0.2 0.9 0.3 0.4 0.3 0.6 1.0 0.2 0.2 1.1 -0.2 0.5 0.4 0.0 0.2 0.7 0.6 -0.2 0.6 0.1 0.5
Number of children fathered 0.8 0.9 6.0 -2.5 -0.8 -0.6 -1.2 -1.8 -0.9 -0.8 -0.1 -0.7 0.3 -1.0 0.3 -1.1 0.8 -1.8 -1.2 -1.1 -0.9 -0.6 -1.9 -0.0 0.2 0.8 -0.3 -0.6 -0.3 -0.8 -1.4 -0.2 0.1 0.3 0.8 -0.4 -0.3 0.3 -1.5 0.4 -0.2 -0.8 -1.4 -0.5 0.6
Reason for reducing amount of alcohol drunk: Health precaution 0.8 1.0 5.0 -1.5 -0.6 -0.8 -1.5 -1.7 -0.1 -1.8 -0.4 -0.8 0.2 -1.1 -0.1 -0.6 0.9 -0.6 -1.3 -1.6 -2.2 -1.3 -1.2 -0.4 0.8 1.8 -0.6 -0.5 -0.4 -0.8 -0.5 -0.6 -0.3 -0.0 1.6 -0.1 -0.8 -0.2 -1.2 -0.5 -0.5 -0.8 -1.1 -1.0 0.3
Age at first live birth 0.9 1.6 4.4 1.6 1.0 0.9 0.5 2.0 1.9 1.7 0.9 1.7 -0.1 1.3 0.4 1.2 -1.0 0.7 1.6 1.7 1.8 1.7 1.7 0.6 -0.7 -1.6 1.2 0.7 1.6 1.4 2.1 1.2 0.7 0.4 -1.5 0.3 1.5 1.1 1.2 1.2 1.1 -0.2 1.3 1.4 -0.0
Pulse wave peak to peak time 1.0 1.2 4.1 0.1 -1.6 -1.6 0.3 -0.0 0.5 -0.9 -0.7 -1.2 -1.4 -1.1 -1.5 -0.9 1.4 1.6 -0.7 -0.9 0.8 -0.6 -0.4 -1.0 2.0 -0.1 -1.4 -1.4 -0.8 -0.9 -0.8 -1.3 -1.3 -0.6 1.0 -1.4 -1.0 -1.1 -0.9 -0.9 -0.9 -1.0 -0.9 -0.9 -1.3
Health satisfaction 0.4 0.5 3.5 -1.5 -0.2 0.1 -1.9 -1.1 0.5 -0.3 -0.6 -0.0 1.0 0.0 0.6 -0.6 0.2 -0.1 0.7 -0.3 -1.7 -0.0 -1.6 0.3 -0.5 0.7 0.2 -0.2 0.4 -0.2 -0.8 0.1 0.7 0.7 -0.2 -0.3 0.2 0.4 -0.7 0.8 0.8 0.2 -0.7 -0.2 0.9
Shortness of breath walking on level ground 0.9 1.0 4.3 -1.8 -0.4 -0.2 -1.6 -2.1 -1.7 -1.0 -0.9 -1.1 0.4 -1.1 -0.0 -0.9 0.7 -0.8 0.6 -1.0 -1.5 -0.5 -1.7 0.0 -0.1 0.7 -0.8 -0.8 -1.6 -1.1 -1.4 -0.8 -0.3 -0.0 0.5 -0.4 -0.6 -0.9 -1.8 -0.6 -0.5 -0.7 -1.6 -1.1 0.3
Qualifications: College or University degree 0.2 0.8 5.4 1.9 0.6 0.2 1.3 1.3 1.1 0.9 0.8 0.7 0.1 0.8 0.2 2.2 -0.3 2.3 -0.1 0.0 1.2 0.6 1.4 0.0 -0.4 0.0 0.1 0.6 0.4 0.3 1.4 0.2 -0.0 -0.5 0.3 0.6 -0.1 0.0 1.5 -0.4 -0.1 -0.0 0.7 0.3 -0.5
Eye problems/disorders: None of the above 1.3 1.5 4.8 -0.0 1.5 1.3 -1.1 0.3 2.0 0.8 1.2 1.3 2.2 1.1 1.4 0.7 -1.1 -0.9 0.0 0.7 0.3 0.9 0.8 1.2 -1.5 0.5 1.5 1.3 1.2 1.2 0.9 1.4 1.6 1.6 -0.7 1.1 1.6 1.5 0.7 1.7 1.4 1.6 1.0 1.3 1.4
Mouth/teeth dental problems: Loose teeth 0.3 0.3 2.2 0.1 -0.5 -0.4 1.0 0.5 1.5 0.0 -0.9 -0.0 -0.5 0.0 -0.7 0.0 0.5 1.2 -0.9 -0.1 0.3 -0.5 -0.2 -0.6 0.2 -0.2 -0.4 -0.3 -0.2 -0.3 0.1 -0.3 -0.6 -0.7 -0.1 -0.7 -0.8 -0.4 0.1 -0.5 -0.1 -0.4 -0.3 -0.2 -0.8
Emphysema/chronic bronchitis 1.5 1.7 6.7 1.7 1.9 2.1 1.8 0.3 -0.5 1.1 2.6 1.0 1.8 1.6 1.4 0.4 -1.2 0.9 2.4 1.6 0.5 1.7 1.0 1.8 -1.3 -0.4 1.0 1.2 -0.2 0.9 0.7 1.1 1.2 1.3 -1.7 1.8 1.0 0.1 0.8 0.6 0.9 0.1 1.0 1.3 1.4
Medication for pain relief, constipation, heartburn 2.1 3.6 11.6 3.0 1.6 1.4 2.1 3.4 -0.7 2.3 1.8 2.5 -0.1 1.8 0.7 1.8 -1.9 2.0 1.3 2.0 3.3 1.3 2.9 0.0 -2.2 -2.1 1.7 1.7 2.7 1.9 2.1 1.7 1.0 0.1 -1.9 1.3 1.0 1.5 3.1 1.0 1.1 1.3 2.4 2.1 -0.1
Neck or shoulder pain in last month 0.4 0.6 2.6 -0.1 -0.1 0.2 0.3 -0.3 -0.5 0.7 -0.1 -1.1 0.2 -1.0 -0.6 -0.2 0.7 0.6 1.5 0.4 -0.6 -0.4 -0.5 -0.9 0.1 -0.8 -0.8 -0.9 -1.5 -1.0 -0.7 -0.8 -0.7 -0.3 -0.8 -0.3 -0.5 -1.6 -1.1 -0.3 -0.4 -1.2 -1.1 -0.5 -0.2
Medication: Blood pressure 0.5 0.8 3.7 -0.8 0.6 1.0 -1.0 -0.7 1.0 -0.2 1.0 0.5 1.5 1.1 1.1 0.7 -0.2 -0.8 0.5 0.6 -0.1 0.9 -0.1 0.7 -0.5 1.3 1.0 0.6 1.0 0.4 0.3 0.8 1.3 1.9 -1.0 1.0 1.1 0.8 -0.0 1.5 1.4 -0.0 -0.1 0.8 1.7
Angina (self-reported) 0.9 1.2 4.0 0.6 -0.8 -0.7 1.4 0.4 -0.5 0.6 -0.5 -1.2 -0.4 -0.7 -1.1 -1.2 1.0 2.0 0.7 -0.6 1.3 -1.0 -0.5 -1.2 -0.0 -0.6 -1.3 -1.4 -1.4 -1.7 -0.7 -1.2 -1.3 -1.5 -0.1 -0.7 -1.0 -1.9 -0.8 -1.3 -1.2 -1.4 -1.4 -0.8 -1.1
Migraine (self-reported) 0.2 0.3 2.4 1.0 0.1 0.0 0.8 0.4 0.2 0.1 1.0 0.3 0.5 0.7 0.3 0.1 -0.1 0.8 -0.0 -0.1 0.9 -0.1 0.4 -0.2 -0.3 0.5 0.3 0.5 0.1 0.5 -0.5 0.3 0.1 -0.4 0.3 -0.1 -0.1 0.4 1.5 -0.5 0.0 1.2 0.5 -0.1 0.1
Medication: Ibuprofen 0.9 1.1 6.6 -1.3 -0.6 -0.7 -1.9 -1.8 0.8 -1.6 -1.2 -0.8 -0.3 -1.3 -0.1 -0.2 0.7 -1.6 -1.6 -1.5 -2.6 -0.5 -1.7 0.2 1.0 1.0 -0.7 -0.6 -0.9 -0.7 -0.3 -0.7 -0.3 0.0 1.7 -0.5 -0.6 -0.4 -1.3 -0.6 -0.6 -0.4 -0.9 -1.3 0.2
Medication: Allopurinol 2.1 2.8 6.6 0.3 -1.9 -1.9 0.8 0.2 -2.1 -0.6 -1.4 -1.6 -1.4 -1.3 -1.9 -1.3 1.7 2.6 -1.2 -1.6 -0.2 -1.8 -1.0 -1.6 1.8 -0.0 -2.2 -1.7 -2.0 -2.0 -1.4 -1.9 -2.1 -2.3 1.5 -1.4 -2.3 -2.3 -0.8 -2.5 -2.2 -0.9 -1.6 -1.8 -2.1
Medication: Omeprazole 0.4 0.4 2.5 -0.6 -0.2 0.1 0.8 -1.2 0.3 -0.7 -0.5 -1.0 0.3 -0.8 0.0 -1.6 0.0 0.0 -0.0 0.1 0.4 -0.5 -1.2 0.5 0.6 0.7 -0.2 -0.3 -1.1 -0.6 -1.2 -0.4 -0.2 -0.6 -0.0 -0.2 -0.4 -0.5 -1.1 -0.8 -0.7 0.4 -0.3 -0.7 -0.0
Medication: Seretide 50 evohaler 0.9 1.0 10.5 -1.3 0.4 0.6 -1.4 -1.0 -1.5 -0.1 0.7 -0.0 1.4 0.4 1.1 -0.9 -0.3 -0.5 0.4 -0.0 -3.2 0.1 -1.1 0.8 -0.1 0.7 0.7 0.5 0.4 0.4 -0.9 0.7 1.0 1.7 -0.1 0.5 0.8 1.1 -0.8 1.5 1.0 1.2 -0.0 0.2 1.8
Mean time to correctly identify matches 0.4 0.8 3.2 0.7 0.4 0.8 0.5 1.0 0.2 0.8 0.5 1.3 -0.1 1.3 0.2 1.1 -0.6 0.2 1.5 1.2 1.8 1.5 1.1 -0.0 -0.9 -1.2 0.8 0.4 0.9 0.7 1.0 0.7 0.4 0.6 -1.8 0.6 0.8 0.6 1.1 0.4 0.9 -0.9 0.5 1.2 0.1
Heart disease (mother) 0.5 0.6 5.3 0.6 -0.2 -0.1 0.7 0.5 -0.8 0.7 -0.2 -0.6 -0.2 -0.1 -0.9 0.0 0.8 2.3 0.9 0.4 0.5 -0.3 -0.2 -1.0 0.6 -0.7 -0.7 -0.9 -1.0 -1.0 -0.0 -0.8 -1.0 -0.9 -0.7 -0.4 -0.8 -1.1 -0.3 -0.8 -0.7 -1.6 -0.8 -0.6 -0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.5 1.8 10.4 -1.0 1.0 0.9 -1.1 -1.0 1.3 -0.1 1.3 0.7 2.5 0.0 1.9 0.5 -0.8 -3.2 -0.4 -0.1 -2.0 -0.4 -0.1 1.7 -0.5 1.7 1.2 1.3 1.1 0.8 -0.1 1.2 1.8 1.4 0.2 1.1 1.5 1.6 0.7 1.5 1.1 2.7 0.5 0.6 2.0
Whole body fat mass 0.2 0.8 6.9 -0.2 0.6 0.9 -0.3 -0.9 0.3 -0.4 1.2 -0.2 1.2 0.3 0.8 -0.3 0.2 -0.4 1.0 0.2 2.0 0.4 -0.1 1.2 -0.0 2.6 0.4 0.4 -0.6 0.0 -0.1 0.1 0.5 2.0 -0.2 1.1 0.9 -0.0 -0.3 0.6 0.5 -0.2 -0.6 0.0 1.8
Leg fat mass (right) 0.1 0.4 3.1 -0.2 0.4 0.6 -0.0 -0.7 0.5 -0.1 1.0 -0.4 0.6 0.0 0.4 -0.6 0.3 -0.4 1.0 0.0 1.5 0.1 -0.3 0.8 -0.2 1.8 0.2 0.1 -0.8 -0.3 -0.3 -0.2 0.2 1.4 -0.2 0.6 0.6 -0.4 -0.7 0.4 0.2 -0.2 -0.8 -0.2 1.2
Arm predicted mass (right) 0.6 3.1 9.9 0.4 2.0 2.2 -0.2 -0.0 -0.7 0.9 1.9 1.5 2.0 1.6 2.2 1.9 -1.6 -0.4 2.3 1.8 0.4 1.7 1.0 2.3 -2.3 1.8 2.0 1.8 1.1 1.7 1.1 1.7 2.1 3.1 -1.5 1.9 2.4 1.7 0.9 2.2 2.4 1.7 1.1 1.5 2.8
Pulse rate, automated reading 0.2 0.7 3.1 -0.8 -0.7 -0.7 -1.7 -1.3 -1.3 -1.4 -0.4 -1.0 -0.3 -1.2 -0.1 -0.9 0.6 -1.5 -1.0 -1.1 -0.5 -0.3 -0.9 0.7 1.8 0.7 -0.7 -0.3 -0.7 -0.3 -0.7 -0.6 -0.4 0.1 1.4 -0.2 -0.4 -0.4 -0.4 -0.7 -0.7 -0.3 -0.3 -1.0 0.1
Alcohol intake frequency. 0.3 0.8 2.4 0.0 -0.7 -0.6 1.5 0.2 0.5 0.2 -0.8 -1.1 -0.7 -0.4 -1.0 -0.1 0.9 1.3 -0.3 -0.2 1.3 -1.2 -0.5 -0.9 0.8 -0.3 -1.0 -0.9 -1.2 -1.1 -0.3 -1.1 -1.1 -0.8 0.1 -0.4 -1.1 -1.3 -0.9 -0.8 -1.2 -1.1 -0.8 -1.1 -0.8
Comparative height size at age 10 0.1 0.8 3.4 -1.3 -0.9 -0.8 -1.2 -1.3 -1.5 -1.3 -0.7 -0.7 0.4 -1.0 -0.1 -0.4 0.9 0.4 -0.4 -1.0 1.2 -0.9 -1.9 0.1 0.9 1.5 -0.7 -0.7 -0.3 -0.7 -1.3 -0.6 -0.3 -0.2 0.9 -0.7 -0.7 -0.1 -0.8 -0.5 -0.4 -0.2 -1.1 -1.1 0.0
Number of full sisters 0.2 0.3 2.1 0.2 -0.2 -0.3 1.4 0.1 -0.5 -0.1 0.1 0.1 -1.0 -0.1 -0.5 -0.3 -0.6 -0.4 -0.5 -0.1 -1.1 -0.8 0.4 -0.5 -0.7 -0.3 -0.1 -0.1 -0.3 0.0 0.2 -0.1 -0.5 -0.8 0.1 -0.4 -0.4 -0.1 -0.2 -0.7 -0.1 0.6 0.3 -0.2 -0.8
Suffer from ‘nerves’ 0.5 0.7 2.1 0.7 -0.5 -0.6 0.1 0.2 0.2 -0.5 -0.9 -0.9 -1.4 -0.4 -0.9 -0.7 0.6 0.9 -0.2 -0.7 0.7 -0.2 -0.2 -1.2 0.7 -0.3 -0.9 -1.0 -0.7 -1.1 0.7 -1.1 -1.0 -1.3 0.4 -0.5 -1.1 -1.5 -0.8 -1.4 -0.7 -1.1 -0.9 -1.2 -1.2
Overall health rating 0.2 0.4 3.2 -0.6 0.1 0.3 0.3 -1.1 0.3 -0.6 -0.1 -0.6 0.9 0.2 0.3 -0.4 0.4 0.1 0.4 -0.3 -0.9 -0.2 -0.7 0.7 0.5 1.8 -0.1 -0.2 -0.8 -0.3 -0.3 -0.3 0.2 1.4 0.1 0.2 0.2 -0.4 -1.3 0.4 0.5 0.2 -0.7 -0.4 1.0
Chest pain or discomfort 0.4 0.6 4.5 0.3 -0.2 -0.2 0.3 0.7 1.7 1.1 -1.0 -0.2 -1.1 0.1 -0.9 0.6 0.2 0.8 0.7 0.3 -0.2 0.2 -0.2 -0.5 0.1 -1.4 -0.4 -1.0 -0.4 -0.7 1.0 -0.7 -0.7 -0.6 -0.6 -0.6 -0.5 -1.3 -0.8 -0.0 -0.0 -2.1 -0.7 -0.4 -1.0
Had major operations 1.0 1.1 4.2 -1.7 -1.1 -1.1 -0.9 -1.5 1.0 -1.3 -0.6 -1.0 -0.5 -0.9 -0.5 -1.5 1.2 -1.0 -2.0 -1.5 0.9 -1.2 -1.4 -0.2 0.8 1.8 -0.7 -1.0 -0.6 -1.0 -1.4 -0.8 -0.3 0.5 1.4 -0.9 -0.1 -0.2 -1.6 0.2 -0.7 -0.4 -1.3 -0.7 0.1
Age at last live birth 0.5 0.7 2.2 1.1 0.7 0.5 -0.4 1.1 0.4 0.7 1.1 1.1 0.6 1.0 0.6 0.8 -0.8 -0.2 0.6 0.8 0.6 0.7 1.5 1.0 -0.3 -0.1 0.9 1.0 1.2 1.2 1.0 1.0 0.7 0.5 -0.2 0.7 1.2 1.1 1.2 0.8 0.8 0.6 1.4 1.0 0.4
Family relationship satisfaction 0.3 0.3 1.5 0.4 0.2 0.2 0.3 0.2 -0.2 -0.3 0.5 0.2 0.4 1.2 0.2 0.8 -0.5 0.0 0.4 0.1 -0.3 1.2 1.2 0.1 -0.1 0.5 0.4 0.5 0.6 0.9 0.5 0.4 0.4 1.1 -0.1 0.6 0.7 0.6 0.4 0.4 0.9 0.1 0.6 0.6 0.4
Leg pain on walking 0.7 0.9 2.4 -0.4 -0.6 -0.7 -0.1 -0.9 0.9 -1.0 -1.3 -1.1 -0.2 -0.6 -0.5 -0.3 0.7 1.0 -0.8 -1.1 0.2 -1.5 -1.1 -0.4 0.1 0.8 -1.0 -0.9 -1.1 -1.2 -0.6 -1.0 -0.9 -1.2 1.2 -0.3 -1.4 -1.2 -0.8 -1.3 -1.2 -1.5 -0.9 -1.3 -0.7
Qualifications: NVQ or HND or HNC or equivalent 0.4 0.4 3.8 0.6 -0.1 -0.2 0.5 1.1 -0.1 0.4 -0.7 0.2 -1.5 0.5 -0.8 0.1 -0.6 0.6 -0.2 0.7 0.4 0.6 1.2 -0.3 0.0 -2.0 0.2 -0.3 0.5 0.3 1.1 -0.1 -0.4 -0.5 -0.8 -0.4 0.1 -0.2 -0.2 -0.0 -0.0 -0.5 0.7 0.4 -1.3
Commuting to job workplace: Car/motor vehicle 1.0 1.2 3.0 -0.6 -1.6 -1.6 -0.1 0.3 0.5 -0.2 -1.0 -0.7 -1.7 -0.7 -1.5 -1.2 1.3 1.3 -1.5 -0.9 -0.4 -1.1 -0.8 -1.5 1.2 -0.7 -1.1 -1.2 -0.8 -0.8 -1.2 -1.1 -1.3 -1.4 1.0 -1.6 -1.0 -0.7 -0.7 -0.8 -1.2 -1.1 -1.0 -0.9 -1.3
Illness, injury, bereavement, stress in last 2 years 1.1 1.3 2.8 0.4 1.2 1.1 0.8 0.8 -0.4 0.9 1.5 1.4 1.5 1.2 1.4 0.3 -1.4 -0.5 0.5 1.0 -1.0 0.8 1.0 1.3 -0.6 -0.0 1.3 1.6 1.5 1.5 0.5 1.6 1.4 0.9 -0.6 1.4 1.1 1.7 1.3 1.3 1.0 1.2 1.6 1.4 1.2
Medication: Aspirin 2.1 2.7 7.1 -2.0 -1.8 -1.5 -0.5 -2.1 -0.4 -1.6 -1.4 -2.2 0.5 -1.9 -1.3 -1.8 2.2 -1.1 -1.6 -1.9 -1.3 -1.5 -1.8 -1.6 1.4 1.8 -1.8 -1.9 -2.2 -2.2 -2.0 -1.9 -1.4 -0.5 1.4 -1.2 -1.3 -1.9 -1.9 -1.2 -1.4 -1.6 -2.7 -1.7 -0.5
Supplements: Vitamin C 0.1 0.2 1.5 -0.4 -0.0 0.1 -0.9 0.3 0.4 0.1 -0.4 0.4 -0.3 0.0 0.2 0.3 -0.4 -1.0 -0.1 0.4 -0.8 -0.2 -0.0 0.1 0.1 -0.2 0.4 0.2 0.7 0.2 -0.1 0.3 0.3 -0.1 -0.4 -0.2 0.1 0.5 -0.2 0.3 0.3 1.2 0.5 0.1 -0.1
Knee pain experienced in last month 0.4 0.6 2.7 1.6 0.8 0.9 1.2 0.9 0.9 1.1 0.3 0.1 0.4 1.2 -0.2 0.4 -0.3 1.6 1.5 1.0 1.6 -0.1 1.1 -0.1 -0.7 -0.0 0.3 0.1 -0.7 0.2 1.2 0.1 -0.2 0.3 -1.1 0.5 0.2 -0.6 0.2 0.1 0.5 -0.8 0.3 0.4 0.0
Hypertension (Self-reported) 0.5 1.5 5.0 -1.4 -1.3 -0.9 -1.0 -1.7 1.5 -1.8 -0.4 -1.0 -0.3 -0.5 -1.0 -2.2 2.1 -0.6 -1.2 -1.0 -0.4 -1.0 -1.8 -1.6 2.1 1.7 -0.8 -1.5 -0.8 -1.5 -1.1 -1.2 -0.6 0.8 0.5 -1.4 -0.7 -0.8 -1.5 0.1 0.0 -0.5 -2.1 -1.1 0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.4 0.5 2.1 -0.2 -0.4 -0.6 0.4 -0.7 1.1 -0.7 -1.1 -0.6 -0.3 -1.0 -0.2 -0.5 0.5 -0.0 -1.4 -0.8 0.7 -0.9 -1.3 -0.3 1.4 1.0 -0.4 -0.4 -0.4 -0.4 -0.7 -0.6 -0.4 -0.4 1.0 -0.8 -0.5 -0.1 -0.6 -0.5 -0.5 0.9 -0.4 -0.9 -0.3
Illnesses of father: Heart disease 3.0 4.1 8.3 -1.1 -2.5 -2.7 -0.5 -1.3 -0.9 -2.0 -2.0 -1.8 -1.9 -1.5 -2.2 -2.1 2.9 0.4 -2.3 -2.4 0.8 -1.6 -1.8 -2.3 2.7 1.4 -2.4 -2.3 -1.6 -2.2 -1.3 -2.3 -2.3 -2.1 2.3 -2.1 -2.1 -1.8 -1.0 -2.5 -2.1 -2.6 -2.4 -2.3 -2.0
Illnesses of siblings: Diabetes 0.8 1.0 4.6 -0.3 -0.7 -0.6 -0.6 0.0 0.4 0.2 -1.0 -0.9 -1.1 -0.6 -1.4 -1.0 1.2 0.0 -0.0 -0.1 -0.1 -1.1 -0.7 -1.5 1.0 -0.7 -1.1 -1.4 -1.2 -1.4 -0.5 -1.2 -1.2 -0.9 -0.3 -0.7 -1.3 -1.5 -1.9 -0.5 -0.8 -2.1 -1.2 -0.8 -1.1
Smoking status: Previous 0.1 0.1 0.9 -0.3 -0.4 -0.2 0.5 0.1 0.3 0.0 -0.0 -0.3 0.1 -0.2 -0.1 0.7 0.1 0.3 0.3 0.2 0.8 0.1 -0.5 -0.4 -0.9 -0.2 -0.1 -0.2 0.2 -0.1 -0.7 0.0 -0.0 0.1 -0.4 -0.3 0.0 0.0 -0.3 0.2 0.3 0.4 -0.1 0.1 -0.0
Forced expiratory volume in 1-second (FEV1), predicted 0.1 0.2 1.2 0.4 0.1 0.1 0.9 0.6 -0.7 0.4 0.1 0.6 -0.2 0.4 0.2 0.9 -0.3 1.1 0.6 0.7 0.6 0.4 0.2 -0.1 0.0 -0.9 0.2 0.2 0.4 0.4 0.6 0.3 0.2 -0.0 -0.6 -0.2 0.3 0.5 0.6 0.0 0.3 0.1 0.3 0.2 -0.2
Whole body fat-free mass 0.9 5.1 11.9 1.4 2.7 2.9 0.4 1.0 -0.8 1.8 2.3 2.1 2.2 2.5 2.5 2.6 -2.2 0.6 3.1 2.6 1.0 2.4 2.0 2.9 -2.8 1.4 2.5 2.3 1.4 2.3 1.8 2.2 2.4 3.4 -2.3 2.5 2.9 1.9 1.5 2.6 2.9 1.7 1.8 2.3 2.9
Leg fat-free mass (right) 1.0 5.1 14.1 1.6 2.7 2.9 0.7 0.8 -0.2 1.6 2.2 1.9 2.3 2.7 2.5 2.6 -2.1 1.0 3.0 2.5 1.6 2.7 2.2 2.9 -2.4 1.8 2.4 2.4 1.1 2.4 1.8 2.1 2.3 3.8 -2.1 2.6 2.9 1.8 1.4 2.6 2.8 1.7 1.9 2.3 3.0
Arm fat percentage (left) 0.1 0.4 4.1 -0.0 0.2 0.5 -0.1 -0.6 0.2 -0.2 0.4 -0.6 0.5 0.1 0.2 -0.5 0.4 -0.1 0.8 -0.1 2.0 -0.0 -0.1 0.3 0.2 1.6 0.0 -0.0 -1.0 -0.5 -0.1 -0.3 -0.1 1.1 -0.1 0.6 0.4 -0.6 -0.5 0.0 -0.1 -0.6 -0.8 -0.2 0.9
Average weekly red wine intake 0.9 1.3 4.0 -0.7 1.2 1.2 -0.7 0.1 1.0 0.3 0.6 1.1 1.4 1.0 1.2 1.6 -1.0 -1.2 0.7 0.9 -0.3 0.6 0.3 0.7 -0.8 0.2 1.5 1.1 2.0 1.2 1.5 1.3 1.5 1.6 -1.0 1.0 1.1 1.3 -0.1 2.0 2.0 0.6 0.9 1.1 1.3
Handedness (chirality/laterality): Left-handed 0.2 0.3 1.6 -0.5 -0.6 -0.5 -0.5 -0.4 -0.1 -0.7 -0.4 -0.7 -0.4 -0.2 -0.6 -0.7 0.8 -1.3 -0.5 -0.4 -0.4 -0.1 -0.4 -0.3 0.5 0.3 -0.5 -0.6 -0.7 -0.4 -0.6 -0.7 -0.4 0.1 0.6 -0.5 -0.1 -0.6 -0.8 -0.1 -0.6 -0.2 -0.4 -0.4 -0.2
Mood swings 0.9 1.6 10.4 -2.1 -1.1 -0.9 -3.2 -2.3 0.4 -2.0 -1.0 -1.3 0.3 -1.4 -0.1 -0.8 1.5 -0.4 -1.4 -1.6 -1.6 -1.0 -1.8 0.1 0.8 2.4 -0.9 -0.8 -0.9 -0.9 -1.7 -0.9 -0.2 0.3 1.6 -0.6 -0.6 -0.5 -1.6 -0.3 -0.4 -0.0 -1.3 -1.1 0.5
Loneliness, isolation 0.2 0.2 2.4 0.7 0.1 0.1 -0.0 0.4 0.6 0.6 0.3 -0.3 0.1 0.7 -0.3 0.7 0.5 1.6 0.5 -0.0 1.1 0.3 0.7 -0.0 -0.2 0.1 -0.3 -0.1 -0.7 -0.2 0.6 -0.3 -0.4 0.1 -0.2 0.3 0.1 -0.7 0.0 -0.2 0.1 -0.3 -0.1 -0.1 0.0
Long-standing illness, disability or infirmity 0.4 0.6 2.7 -0.0 -0.1 0.3 1.0 -0.8 0.6 -0.4 0.1 -1.0 1.2 0.0 -0.2 1.0 0.6 1.5 1.2 -0.2 -1.6 -0.2 -0.4 0.2 0.6 1.4 -0.6 -0.4 -1.5 -0.6 -0.6 -0.8 -0.4 0.2 -0.2 0.4 -0.6 -1.4 -0.8 -0.7 -0.3 -0.9 -0.9 -0.7 0.4
Ever had bowel cancer screening 1.1 1.3 5.2 1.2 1.5 1.6 1.4 1.5 -1.2 2.2 0.7 1.1 0.9 1.1 0.8 -0.3 -1.5 1.3 1.3 2.0 -0.0 0.6 1.1 0.3 -1.4 -0.9 0.9 0.9 0.3 0.8 0.6 1.0 0.8 0.0 -2.3 1.3 0.4 0.3 0.2 0.9 0.9 0.4 1.2 1.4 0.3
Diabetes diagnosed by doctor 0.2 0.3 3.1 -0.3 -0.3 0.0 0.0 -0.7 -1.7 -0.3 -0.4 -0.7 -0.0 0.0 -0.3 0.1 0.1 0.9 1.0 0.2 -1.5 -0.6 -0.4 -0.4 0.5 -0.1 -0.2 -0.4 -0.9 -0.2 -0.8 -0.4 -0.2 0.4 -0.4 -0.5 0.2 -0.4 -0.6 -0.1 0.2 0.5 -0.5 -0.3 0.3
Ever had stillbirth, spontaneous miscarriage or termination 1.3 1.3 3.9 0.7 -1.3 -1.6 1.2 0.2 1.0 -1.3 -1.9 -0.6 -1.4 -1.1 -1.3 0.1 0.9 1.9 -1.6 -1.4 0.4 -1.5 -0.1 -1.2 2.0 0.8 -0.9 -0.7 -0.2 -0.5 -0.3 -0.8 -1.3 -1.6 1.6 -0.9 -1.3 -0.2 0.9 -1.9 -1.3 -0.5 -0.6 -0.9 -1.4
Friendships satisfaction 0.1 0.2 1.0 0.4 -0.3 -0.3 0.4 0.7 0.7 0.5 -0.0 -0.0 -0.2 0.4 -0.6 0.3 0.4 0.3 0.1 0.1 -0.1 -0.4 0.1 -1.0 -0.2 -0.4 -0.2 -0.5 -0.1 -0.3 0.2 -0.2 -0.4 -0.3 -0.4 -0.9 -0.1 -0.2 0.0 -0.0 -0.0 -0.6 -0.4 0.0 -0.6
Qualifications: nursing, teaching 0.2 0.3 4.0 0.4 0.4 0.4 -0.3 0.6 2.0 0.4 0.2 0.3 -0.3 0.4 -0.0 1.0 -0.1 0.5 0.2 0.4 0.0 0.1 0.6 -0.6 -0.3 -0.7 0.2 0.0 0.0 0.0 1.5 0.1 0.1 -0.2 -0.7 0.1 0.1 -0.1 -0.1 0.1 0.5 -0.5 0.2 0.3 -0.3
Commuting to job workplace: Walk 3.5 3.7 9.4 0.2 2.2 2.1 -0.3 0.4 0.1 0.7 1.0 1.9 2.2 1.7 2.6 3.1 -2.6 -1.0 0.6 1.3 0.3 1.4 1.3 2.4 -1.8 0.9 2.5 2.3 2.9 2.1 2.1 2.4 2.5 2.0 -1.4 2.4 2.1 2.7 2.1 2.1 2.1 2.2 1.9 2.1 2.1
Eye problems/disorders: Cataract 2.3 2.6 5.7 -1.1 -2.1 -2.0 0.0 -0.9 -0.5 -1.4 -2.0 -1.6 -2.3 -1.7 -1.8 -1.3 1.6 0.4 -1.2 -1.4 -1.5 -1.5 -2.0 -2.2 2.0 -0.6 -1.8 -2.0 -1.0 -1.9 -1.0 -1.7 -1.8 -1.9 1.2 -1.9 -1.8 -1.4 -1.1 -1.7 -1.6 -2.4 -2.0 -1.8 -1.7
Mouth/teeth dental problems: Mouth ulcers 1.1 1.8 10.2 2.4 0.5 0.6 3.2 2.4 -0.2 2.6 0.1 0.6 -0.9 1.1 -0.6 1.0 -0.6 2.5 2.4 1.9 2.1 0.8 1.2 -0.7 -0.5 -2.6 0.4 -0.0 0.3 0.6 0.9 0.4 -0.3 -0.8 -2.2 -0.5 0.1 -0.2 1.5 0.2 0.6 -0.2 0.6 0.8 -0.8
Medication for cholesterol 0.6 0.9 3.0 -1.1 -0.9 -0.9 -1.5 -0.7 0.1 -0.6 -1.1 -1.4 -1.3 -0.6 -0.9 -0.6 0.7 0.4 -0.3 -0.5 -0.2 -0.9 -0.8 -0.6 -0.1 0.1 -1.2 -0.9 -1.2 -0.9 -1.1 -1.1 -1.0 -0.9 0.8 -0.8 -1.1 -1.3 -1.7 -0.8 -1.1 -1.0 -0.6 -1.1 -0.9
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.0 1.2 3.4 -1.8 -1.1 -0.7 -0.7 -0.8 -1.7 -0.1 -1.3 -1.3 -1.0 -1.4 -0.9 -0.6 1.1 -1.0 0.2 -0.3 -0.8 -0.5 -1.6 -0.6 0.4 -0.9 -1.0 -1.4 -1.8 -1.6 -0.8 -1.1 -1.0 -1.1 -0.4 -1.2 -0.7 -1.2 -1.8 -0.5 -1.0 -1.3 -1.7 -0.8 -0.6
Back pain experienced in last month 0.5 0.7 2.6 -1.1 -0.8 -0.6 0.0 -1.1 -1.5 -0.7 -0.4 -1.2 0.2 -1.1 -0.8 -0.7 1.3 -0.6 -0.1 -0.4 -0.4 -0.4 -1.4 0.3 0.8 0.8 -0.9 -1.1 -1.4 -0.9 -0.5 -1.0 -0.8 0.2 0.5 -0.9 -0.2 -0.9 -1.6 -0.3 -0.5 -1.2 -1.3 -0.9 -0.1
Mineral and other dietary supplements 0.8 1.1 3.3 -0.2 -0.7 -0.8 1.5 -0.4 -0.4 -0.8 -1.1 -1.4 -0.6 -1.0 -0.9 -1.5 0.9 1.2 -1.1 -0.7 -0.2 -1.2 -0.7 -0.5 1.8 0.4 -1.2 -0.7 -1.6 -0.9 -1.5 -1.2 -1.2 -0.7 0.9 -0.7 -1.6 -1.5 -1.4 -1.0 -1.3 -0.1 -0.4 -1.2 -0.9
Breast cancer (self-reported) 0.8 1.0 2.7 0.9 -0.6 -0.9 0.4 0.7 0.2 0.1 -1.1 -0.8 -1.6 -0.2 -1.5 -0.9 1.1 0.9 -1.1 -0.3 0.2 -0.1 -0.2 -1.4 1.6 -0.8 -1.1 -1.0 -1.3 -0.8 0.0 -1.3 -1.6 -1.0 0.7 -1.0 -1.4 -1.6 -0.9 -1.0 -0.9 -1.3 -0.4 -1.0 -1.6
Asthma (self-reported) 0.1 0.2 1.0 0.4 0.3 0.4 0.0 0.3 0.9 0.4 0.5 -0.4 0.2 0.5 0.3 0.3 -0.5 0.4 1.0 0.5 -0.7 0.1 0.1 0.4 -0.5 -0.2 0.3 0.3 -0.0 0.3 -0.7 0.2 0.2 0.4 -0.5 0.4 -0.0 0.0 -0.1 0.2 0.1 0.1 0.4 -0.0 0.4
Osteoporosis (self-reported) 0.1 0.1 1.5 0.3 -0.0 -0.1 0.2 0.0 0.5 0.0 0.8 -0.2 0.3 -0.3 0.0 -0.2 -0.3 -0.0 -0.4 0.1 -0.7 -0.8 -0.0 0.3 -0.0 -0.2 0.0 0.3 0.1 0.3 -0.2 0.1 0.1 -0.2 0.3 -0.2 0.1 0.1 -0.0 0.0 0.1 1.2 0.6 -0.2 -0.1
Osteoarthritis (self-reported) 0.7 0.9 8.2 2.2 0.2 0.2 2.9 1.5 1.2 1.3 0.4 -0.1 -0.2 0.5 -0.6 0.9 -0.0 2.2 1.6 0.8 1.8 -0.1 1.4 -0.2 -0.3 -0.7 -0.1 -0.1 -0.7 0.2 0.4 -0.1 -0.6 -0.4 -0.8 -0.2 -0.1 -0.8 0.8 -0.5 0.1 0.1 0.4 0.2 -0.4
Medication: Aspirin 2.3 3.0 7.4 -2.4 -1.9 -1.6 -1.1 -2.6 -0.4 -2.2 -1.4 -2.2 1.0 -2.0 -1.1 -1.7 2.2 -1.7 -1.9 -2.1 -1.6 -1.4 -2.1 -1.4 1.4 2.4 -1.8 -1.7 -2.0 -2.1 -2.1 -1.9 -1.2 -0.3 1.7 -1.1 -1.3 -1.6 -1.9 -1.1 -1.3 -1.5 -2.7 -1.7 -0.2
Medication: Gliclazide 0.8 0.9 3.5 -1.2 0.2 0.5 -0.1 -1.4 -1.2 -0.7 0.3 0.5 1.9 -0.1 1.5 -0.2 -0.5 -0.2 -0.4 -0.2 -0.9 1.2 -0.8 0.9 -0.2 1.5 0.8 1.0 0.7 0.8 -0.8 1.0 1.4 1.2 0.2 0.6 1.3 1.3 0.4 1.0 0.7 1.3 0.4 0.4 1.8
Illnesses of father: None of the above (group 1) 0.3 0.4 3.1 0.7 0.6 0.5 0.7 0.6 -0.3 0.6 0.4 0.3 0.5 -0.3 0.7 0.3 -0.8 0.8 0.5 0.4 -1.1 0.2 0.3 1.2 0.0 -0.4 0.4 0.8 0.1 0.6 -0.2 0.5 0.5 0.3 -0.1 0.5 0.4 0.2 0.4 0.3 0.1 1.8 1.0 0.2 0.3
Smoking status: Current 0.3 0.5 3.3 -0.5 0.3 0.4 0.5 -1.1 -1.4 -0.5 0.8 -0.2 0.6 0.1 0.8 -0.6 -0.4 -0.3 0.2 -0.2 -1.7 -0.1 -0.1 1.8 -0.1 1.6 0.1 0.7 -0.5 0.4 -0.4 0.2 0.5 0.9 0.6 0.9 0.6 0.3 0.5 -0.1 -0.0 0.7 0.3 -0.2 1.2
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.9 1.9 5.4 1.9 1.6 1.3 2.0 2.3 -0.3 1.7 1.4 1.5 1.0 1.9 0.9 1.9 -1.2 1.3 0.1 1.0 0.1 0.9 2.2 0.9 -0.9 0.5 1.3 1.6 1.8 1.4 2.1 1.2 1.0 0.8 -0.8 1.8 0.8 0.9 1.7 1.2 1.2 1.5 1.7 1.2 0.6
Whole body water mass 0.9 4.9 12.0 1.4 2.6 2.9 0.3 1.0 -0.7 1.8 2.2 2.0 2.2 2.5 2.4 2.7 -2.2 0.6 3.0 2.6 1.0 2.4 1.9 2.8 -2.8 1.3 2.5 2.3 1.4 2.3 1.9 2.2 2.4 3.5 -2.3 2.4 2.8 1.9 1.5 2.6 2.9 1.8 1.8 2.2 2.9
Leg predicted mass (right) 0.9 4.9 14.0 1.5 2.6 2.9 0.7 0.8 -0.2 1.6 2.1 1.8 2.3 2.6 2.4 2.5 -2.0 1.0 3.0 2.5 1.6 2.6 2.1 2.8 -2.4 1.9 2.4 2.3 1.1 2.3 1.8 2.1 2.3 3.7 -2.1 2.6 2.8 1.7 1.4 2.6 2.8 1.6 1.8 2.2 3.0
Arm fat mass (left) 0.2 1.0 5.4 0.1 1.1 1.4 -0.2 -0.5 0.2 0.3 1.3 0.3 1.5 0.8 1.1 0.2 -0.3 -0.5 1.6 0.8 1.7 0.9 0.3 1.4 -0.7 1.9 0.9 0.8 -0.2 0.4 0.4 0.5 0.9 2.3 -0.9 1.3 1.3 0.3 -0.0 1.1 1.1 0.1 -0.1 0.5 1.9
Number of self-reported non-cancer illnesses 0.2 0.3 1.3 -0.5 -0.1 0.3 -0.7 -0.9 1.1 -0.5 0.5 -0.8 1.0 0.2 0.1 0.3 0.3 0.7 0.5 -0.1 -0.5 -0.1 -0.6 -0.1 0.5 0.9 -0.3 -0.3 -0.9 -0.7 -0.7 -0.4 0.0 0.4 -0.3 0.2 -0.2 -0.7 -0.9 -0.3 -0.1 -0.0 -0.9 -0.3 0.5
Average weekly champagne plus white wine intake 0.4 0.6 3.1 1.2 0.2 0.2 0.4 1.1 -1.0 1.1 -0.1 0.4 -0.6 0.5 -0.3 1.3 -0.2 1.8 1.4 0.7 0.8 0.2 0.5 -0.6 -0.7 -1.5 0.1 -0.1 -0.1 -0.0 0.8 0.1 -0.3 -1.1 -0.7 0.1 -0.3 -0.3 1.3 -0.7 -0.2 -1.5 0.1 0.1 -0.6
Miserableness 0.3 0.5 7.7 -1.0 -0.4 -0.2 -2.8 -1.2 0.6 -1.0 -0.6 -0.7 0.0 -0.4 0.1 0.3 0.7 -0.6 -1.0 -0.4 -0.2 0.2 -0.9 -0.0 0.3 1.0 -0.4 -0.4 -0.2 -0.5 0.1 -0.4 0.2 0.5 0.6 -0.1 -0.2 -0.3 -0.9 0.2 0.2 -0.2 -0.5 -0.4 0.4
Guilty feelings 0.4 0.6 3.7 -1.7 -0.6 -0.3 -1.9 -1.8 0.6 -1.3 -0.1 -0.9 -0.1 -0.7 0.2 -0.2 0.6 -1.7 -0.3 -0.8 -0.6 -0.3 -1.0 0.4 -0.4 0.6 -0.4 -0.2 -0.9 -0.5 -1.3 -0.3 0.0 0.2 0.7 -0.2 0.2 -0.1 -1.4 -0.2 -0.4 0.3 -0.6 -0.5 0.7
Wears glasses or contact lenses 1.8 2.0 5.2 -2.0 -1.4 -1.1 -1.0 -2.2 -1.0 -2.3 -0.9 -1.5 0.0 -1.8 -0.7 -1.9 1.6 -1.4 -1.6 -1.4 -1.8 -1.5 -2.1 -0.9 1.0 2.1 -1.4 -1.1 -1.5 -1.7 -1.9 -1.3 -0.8 -0.5 1.2 -1.1 -1.4 -1.2 -2.0 -0.9 -1.0 0.6 -1.3 -1.5 -0.2
Ever taken oral contraceptive pill 0.8 0.9 3.1 0.3 0.6 0.6 0.7 0.4 1.3 0.3 1.6 1.2 0.7 0.8 0.7 1.8 -0.6 -0.3 0.5 0.6 0.1 0.7 0.7 1.0 -1.1 0.2 1.1 0.9 1.2 1.1 1.2 1.0 0.9 1.3 -0.3 0.7 1.5 1.3 1.0 1.1 1.1 0.3 0.8 1.1 1.0
Hearing aid user 0.2 0.3 1.9 -0.3 -0.2 -0.2 0.9 -0.5 -0.9 -0.6 -0.0 -0.1 0.7 -0.5 0.3 -0.0 0.1 0.4 -1.2 -0.6 -0.7 -0.3 -0.5 0.3 -0.3 1.2 0.0 0.1 -0.1 -0.2 -0.3 -0.0 0.1 -0.1 0.5 -0.3 0.2 0.3 0.3 -0.4 -0.5 1.4 -0.3 -0.5 0.2
Mother’s age at death 0.6 0.7 2.6 0.1 0.7 0.9 1.2 0.2 0.1 -0.1 0.4 0.7 1.0 0.7 1.0 0.3 -1.3 -0.0 -0.1 0.8 -0.7 0.4 0.7 0.8 -0.9 0.3 0.8 1.3 1.3 1.2 0.3 0.9 1.0 0.4 -0.8 1.3 0.7 0.9 1.4 0.4 0.5 1.6 1.5 0.9 0.5
Financial situation satisfaction 0.6 0.8 4.8 0.1 0.9 1.0 0.1 0.1 2.2 0.7 1.2 0.5 0.8 1.1 0.9 0.4 -0.7 0.3 0.6 0.5 -0.3 1.3 0.5 0.7 -1.4 0.2 0.8 0.5 0.5 0.6 1.0 0.7 1.0 1.5 -1.0 0.8 1.3 0.5 0.2 1.3 1.1 -0.2 0.2 1.0 1.1
Tinnitus: Yes, now most or all of the time 0.1 0.1 1.3 -0.8 -0.3 -0.4 -0.3 -0.2 -0.3 -0.1 0.0 -0.4 -0.0 -0.1 0.0 -0.6 0.1 -1.1 -0.2 -0.3 -0.6 0.0 -0.6 0.1 -0.4 0.1 -0.0 -0.1 0.0 -0.1 -0.5 0.0 0.0 0.0 0.5 -0.3 0.2 0.2 -0.8 0.3 0.1 0.1 -0.1 -0.2 0.2
Commuting to job workplace: Public transport 0.3 0.4 1.6 0.6 -0.2 -0.2 1.2 -0.3 -0.7 -0.6 -0.5 -0.9 -0.0 -0.7 -0.2 0.4 0.4 1.0 0.7 -0.6 0.5 -0.7 -0.4 0.0 0.8 0.6 -0.8 -0.3 -0.9 -0.8 -0.5 -0.6 -0.5 -0.4 0.5 0.1 -1.0 -1.1 -0.3 -1.1 -0.5 0.4 -0.3 -1.0 -0.1
Eye problems/disorders: Glaucoma 0.7 0.8 5.6 1.7 0.2 0.4 1.7 1.4 -0.5 1.1 0.9 0.3 -0.5 1.0 -0.0 1.5 -0.6 0.8 1.6 0.9 2.4 0.5 1.7 0.5 -0.0 -0.2 0.2 0.4 -0.0 0.6 0.5 0.3 -0.1 0.4 -0.9 0.5 0.5 0.0 0.8 -0.0 0.4 1.1 0.7 0.6 0.1
Medication: Blood pressure 0.1 0.2 1.3 -0.2 0.0 0.1 0.2 -0.9 -0.3 -0.6 0.8 -0.1 0.7 0.1 0.1 -1.1 0.7 -0.2 -0.2 -0.5 -0.2 0.3 -0.5 -0.1 1.1 0.9 0.0 -0.2 -0.4 -0.3 -0.3 -0.3 0.2 1.2 0.3 0.1 0.1 -0.3 -0.5 0.4 0.4 0.1 -0.6 -0.4 0.9
Pain type(s) experienced in last month: Hip pain 1.0 1.2 5.1 2.3 1.3 1.3 1.7 0.8 -1.6 0.9 1.9 0.3 1.2 0.7 0.7 1.7 -1.0 1.3 1.8 1.0 1.5 -0.4 1.7 1.0 -0.2 1.1 0.6 1.1 0.1 0.8 1.5 0.5 0.4 0.2 -0.7 1.9 0.2 -0.4 1.3 -0.4 0.5 -0.4 1.0 0.2 0.8
Supplements: Fish oil (including cod liver oil) 0.6 0.8 3.6 0.6 0.5 0.5 -0.5 0.7 0.4 0.5 0.6 1.3 0.4 1.0 0.7 1.9 -0.9 -0.5 1.0 0.7 0.8 0.6 1.1 0.4 -1.5 -0.6 1.0 0.7 1.6 0.9 1.4 1.0 0.8 0.2 -0.9 0.8 1.3 1.4 1.5 0.3 0.9 -0.0 0.6 1.0 0.3
High cholesterol (Self-reported) 0.4 0.8 3.2 1.8 1.3 1.1 0.8 0.7 0.2 0.6 0.8 0.9 1.3 1.4 0.9 0.4 -0.8 0.3 0.9 0.5 0.3 0.9 1.2 0.4 -0.4 -0.2 0.9 0.9 0.8 0.6 1.6 0.8 0.8 0.0 -0.8 1.0 0.9 0.2 1.7 -0.0 0.4 1.0 1.0 0.6 0.4
Medication: Bendroflumethiazide 0.2 0.4 4.9 0.2 -0.4 -0.4 0.1 -0.2 2.2 -0.6 0.4 -0.3 -0.7 0.4 -0.5 -0.5 1.0 0.3 -0.1 -0.3 -0.1 -0.5 -0.1 -0.8 1.0 0.8 -0.3 -0.6 -0.1 -0.5 -0.3 -0.5 -0.4 0.1 0.5 -0.2 -0.3 -0.5 0.0 -0.2 -0.2 -1.4 -0.7 -0.4 -0.1
Medication: Paracetamol 0.3 0.4 1.9 0.1 -0.1 -0.1 -0.3 -0.4 1.0 0.3 -0.1 -1.0 0.1 -0.2 -0.2 -0.8 0.4 1.0 0.2 -0.4 -0.8 -1.4 -0.8 0.2 0.7 0.7 -0.7 -0.5 -1.3 -0.6 -0.7 -0.7 -0.5 -0.4 0.4 -0.4 -0.8 -1.1 -0.7 -0.4 -0.4 -0.1 -0.6 -1.0 -0.1
Medication: Lisinopril 0.3 0.4 4.5 -0.6 -0.2 0.1 -1.2 -0.8 0.3 -0.7 -0.2 -1.0 0.5 -0.2 0.0 -2.1 0.8 0.2 -0.7 -0.5 -0.7 0.1 -0.7 -0.2 0.2 0.6 -0.2 -0.3 -1.0 -1.0 -0.6 -0.5 -0.1 0.3 0.0 -0.2 -0.4 -0.7 -0.9 -0.2 -0.5 0.7 -1.0 -0.4 0.5
Medication: Atorvastatin 0.1 0.2 1.3 -0.7 0.0 0.2 -0.4 -0.6 -1.2 0.0 -0.3 0.1 0.6 0.2 0.3 -0.1 -0.0 -0.1 0.6 -0.1 -0.4 0.0 -0.5 -0.2 -0.8 -0.7 0.2 -0.0 0.2 -0.2 -0.4 0.3 0.4 -0.2 -0.1 0.1 0.2 0.3 -0.0 0.3 -0.1 -0.6 -0.4 0.2 0.4
Illnesses of father: High blood pressure 1.0 1.3 4.4 -1.4 -1.5 -1.6 -1.4 -1.3 0.3 -1.7 -0.7 -0.9 -0.9 -1.1 -1.0 -0.7 1.7 -0.4 -2.1 -1.6 -0.9 -0.9 -1.4 -0.6 0.9 1.5 -1.0 -1.3 -0.1 -1.0 -0.4 -1.0 -0.8 -0.5 1.7 -1.3 -1.0 -0.4 -0.9 -0.4 -0.6 -1.3 -1.3 -1.1 -0.4
Alcohol drinker status: Never 0.7 0.8 3.1 -0.5 -0.6 -0.4 0.2 -0.6 -0.5 -0.1 -1.0 -1.0 -0.0 -0.5 -0.5 -0.3 0.9 1.4 -0.4 -0.6 -1.1 -1.1 -1.1 -0.7 0.3 0.1 -1.0 -0.8 -1.5 -1.5 -0.3 -0.9 -0.9 -1.4 0.2 -0.0 -1.1 -1.5 -1.0 -1.2 -1.3 -1.8 -1.1 -0.9 -0.6
Ever smoked 0.2 0.3 2.4 -0.7 -0.1 0.2 0.5 -1.0 -0.7 -0.3 0.3 -0.6 0.7 -0.2 0.6 0.0 -0.0 0.9 0.7 -0.1 -0.1 0.2 -1.1 0.3 -1.6 0.5 -0.2 -0.1 -0.7 -0.3 -1.0 -0.0 0.3 0.5 -0.1 0.1 0.5 -0.0 -0.5 -0.1 -0.1 0.5 -0.5 -0.2 0.7
Basal metabolic rate 0.8 4.7 12.6 1.2 2.6 2.8 0.3 0.8 -0.5 1.6 2.3 1.9 2.2 2.4 2.4 2.4 -2.0 0.4 3.0 2.4 1.3 2.4 1.8 2.8 -2.6 1.6 2.4 2.2 1.3 2.2 1.7 2.1 2.3 3.6 -2.2 2.4 2.8 1.9 1.4 2.6 2.8 1.6 1.6 2.1 2.9
Leg fat percentage (left) 0.2 0.9 3.4 -0.9 -0.7 -0.5 0.2 -1.1 1.0 -0.9 0.2 -1.0 -0.2 -1.1 -0.5 -1.8 1.2 -1.1 -0.3 -1.1 1.2 -1.0 -1.1 -0.4 0.8 1.6 -0.6 -0.8 -1.2 -1.2 -1.0 -1.0 -0.6 0.3 0.9 -0.4 -0.4 -0.8 -1.1 -0.4 -0.8 -0.6 -1.6 -1.0 0.3
Arm fat-free mass (left) 0.7 3.7 9.9 0.9 2.3 2.6 0.1 0.5 -0.7 1.5 2.1 1.8 2.1 1.9 2.2 2.0 -1.7 -0.2 2.8 2.3 0.6 1.9 1.1 2.5 -2.6 1.4 2.2 1.9 1.2 1.8 1.4 1.8 2.1 3.1 -2.1 2.0 2.4 1.6 1.2 2.5 2.5 1.5 1.2 1.7 2.8
Number of operations (self-reported) 2.7 4.0 9.7 -2.6 -2.3 -2.1 -1.6 -2.5 -0.4 -2.3 -1.6 -2.5 -1.1 -2.0 -1.7 -1.9 2.6 -1.2 -2.4 -2.3 -0.9 -2.3 -2.8 -1.6 1.4 1.8 -2.0 -2.3 -2.2 -2.4 -2.1 -2.3 -1.6 -0.1 1.9 -2.1 -1.3 -1.8 -3.1 -0.9 -1.3 -1.6 -2.8 -2.2 -0.8
Average weekly beer plus cider intake 2.6 3.7 12.4 0.3 -2.3 -2.4 2.3 0.3 -2.2 -1.1 -2.5 -1.7 -3.5 -1.3 -2.5 -0.9 1.7 2.5 -1.3 -1.4 -0.1 -1.8 -0.5 -1.3 1.4 -1.0 -2.3 -1.9 -2.0 -1.7 -1.6 -2.1 -2.7 -2.6 1.6 -2.2 -2.2 -2.2 -0.8 -2.7 -2.5 -0.8 -1.1 -1.7 -2.8
Irritability 0.2 0.4 2.1 0.0 -0.6 -0.5 0.7 -0.0 0.2 0.1 -0.3 -0.6 0.3 -0.3 -0.5 0.2 0.6 1.5 -0.2 -0.5 -0.0 -0.7 -0.3 -0.6 -0.2 -0.1 -0.8 -0.5 -1.0 -0.7 -0.4 -0.7 -0.8 -1.0 0.3 -0.3 -0.7 -0.9 -0.5 -1.0 -0.9 0.1 -0.5 -1.0 -0.5
Risk taking 0.3 0.5 2.1 0.0 -0.7 -0.5 -0.0 -0.1 -1.5 -0.3 -1.0 -0.7 -0.9 -0.0 -0.9 0.1 0.6 0.3 0.2 -0.0 1.1 -0.2 -0.2 -0.4 0.3 -1.1 -0.9 -0.8 -1.3 -0.7 -0.1 -0.9 -0.9 -0.5 -0.0 -0.5 -0.6 -1.2 -0.9 -1.0 -0.6 -0.9 -0.6 -0.6 -0.8
Ever had prostate specific antigen (PSA) test 0.3 0.3 2.1 0.2 0.4 0.6 1.0 0.4 -0.5 0.9 0.3 0.8 0.7 0.1 0.7 1.5 -0.7 0.1 0.6 0.4 0.1 0.1 0.5 0.9 -0.8 -0.2 0.4 0.5 0.3 0.0 0.5 0.6 0.7 -0.1 -0.7 0.5 1.1 0.2 0.3 0.4 -0.1 0.8 0.2 0.6 0.6
Fractured/broken bones in last 5 years 0.5 0.6 2.9 0.6 0.9 0.9 0.1 0.3 1.7 0.2 0.3 1.0 0.6 0.4 0.5 0.9 -1.1 -1.1 0.7 0.9 1.0 0.1 0.9 0.2 -1.0 0.2 1.0 0.9 0.8 1.1 0.8 0.9 0.7 0.9 -0.9 0.9 0.6 0.7 0.4 0.5 1.2 0.3 0.9 0.5 0.7
Age started oral contraceptive pill 0.8 1.0 3.6 -1.1 -0.6 -0.4 -0.7 -1.3 -1.5 -0.8 0.1 -1.5 -0.0 -0.6 -0.7 -1.9 0.7 -0.6 0.2 -0.3 -1.9 -1.3 -1.6 -0.9 0.1 0.4 -0.9 -1.0 -1.2 -1.3 -1.1 -1.0 -0.8 -0.4 -0.0 -0.6 -1.0 -1.2 -1.7 -0.6 -0.6 -1.0 -1.1 -1.3 -0.2
Diastolic blood pressure, automated reading 0.5 1.7 4.8 -1.1 -1.4 -1.3 -2.1 -0.8 1.8 -1.0 -1.0 -0.8 -1.2 -0.9 -1.4 -1.9 2.2 -0.4 -1.4 -0.9 0.8 -1.0 -1.6 -1.9 1.8 1.5 -0.9 -1.6 -0.4 -1.3 -1.0 -1.4 -1.0 0.5 0.7 -1.6 -1.2 -0.9 -1.9 0.4 0.0 -1.5 -1.6 -1.3 -0.5
Ever depressed for a whole week 0.4 0.5 4.0 -1.4 -0.3 -0.3 -1.2 -1.1 2.0 -0.8 -0.5 -0.5 0.2 -0.8 -0.1 0.1 0.4 -1.9 -0.8 -0.7 0.2 -0.5 -1.1 -0.3 0.6 0.5 -0.4 -0.4 -0.3 -0.5 0.2 -0.4 -0.0 0.2 0.5 -0.4 -0.2 -0.3 -1.2 0.2 0.0 -0.7 -0.6 -0.5 -0.0
Unable to work because of sickness or disability 1.2 1.6 5.5 0.3 -1.3 -1.3 0.5 0.1 1.6 -0.5 -1.1 -1.3 -1.0 -1.3 -1.6 -0.2 0.8 2.3 -0.2 -1.0 -1.2 -1.9 -0.8 -1.4 0.8 -0.2 -1.4 -1.4 -1.6 -1.4 -0.2 -1.4 -1.7 -1.5 0.7 -1.0 -1.5 -1.6 -1.2 -1.7 -1.3 -1.0 -1.4 -1.5 -1.4
Commuting to job workplace: Cycle 0.4 0.5 2.5 0.4 0.6 0.5 0.6 1.2 0.6 1.6 -0.0 0.8 -0.1 0.8 -0.0 1.3 -0.4 -0.4 0.1 0.5 0.9 0.5 0.6 -0.3 -1.2 -1.3 0.5 0.1 0.7 -0.0 1.2 0.4 0.1 -0.3 -1.2 0.3 0.0 0.2 0.4 0.6 0.4 -0.8 -0.0 0.6 -0.5
Myopia 2.6 3.8 7.0 1.7 2.3 2.4 0.9 1.8 0.9 1.9 1.8 2.2 1.4 2.6 1.8 1.8 -2.7 0.5 2.1 2.6 1.6 2.5 2.3 1.6 -1.9 -0.5 2.2 2.0 2.1 2.1 1.9 2.1 2.0 1.6 -2.5 2.0 1.9 1.5 1.5 1.9 2.0 2.0 2.4 2.2 1.3
Vascular/heart problems diagnosed by doctor 0.4 1.2 4.7 0.9 1.0 0.6 1.0 1.3 -1.5 1.2 0.4 0.8 0.2 0.4 0.9 2.1 -1.9 -0.3 0.6 0.7 0.1 0.8 1.6 1.5 -2.2 -1.1 0.7 1.4 0.9 1.5 1.2 1.1 0.7 -0.5 -0.1 1.1 0.9 1.0 1.4 0.1 0.0 1.1 2.0 0.9 0.0
Cholesterol lowering medication 0.2 0.4 4.0 1.0 0.5 0.6 2.0 0.2 -0.8 0.6 0.8 0.2 1.0 0.2 0.4 0.4 -0.2 0.9 1.3 0.1 0.1 0.1 0.6 0.0 -0.3 0.0 0.3 0.2 -0.2 -0.1 0.6 0.3 0.1 0.2 -0.7 0.7 0.7 -0.1 0.7 -0.2 0.0 -0.3 -0.2 0.4 0.6
Medication: Omeprazole (e.g. Zanprol) 0.5 0.7 3.2 -1.2 -0.4 0.0 0.6 -1.5 0.7 -0.5 -0.9 -1.2 0.0 -0.9 -0.3 -1.2 0.2 -0.1 0.2 0.1 0.4 -0.8 -1.6 0.2 0.6 0.2 -0.5 -0.7 -1.6 -1.0 -1.2 -0.7 -0.4 -0.7 -0.4 -0.6 -0.5 -0.8 -1.8 -0.7 -0.6 0.2 -0.9 -0.8 -0.2
Pain experienced in last month 0.2 0.3 1.6 0.0 0.2 0.0 -0.1 0.8 0.3 0.2 -0.4 0.8 -0.2 0.2 0.1 -0.0 -0.6 -0.9 -0.7 0.4 0.0 0.6 0.4 -0.2 -0.4 -0.9 0.5 0.5 1.3 0.4 0.4 0.5 0.2 -1.0 -0.1 0.1 -0.4 0.6 1.3 -0.0 0.0 0.1 0.7 0.5 -0.7
Supplements: Calcium 0.2 0.2 1.8 -0.3 0.0 -0.0 0.2 0.5 -0.6 1.2 -0.3 -0.2 -0.4 -0.4 -0.1 0.2 -0.1 -0.7 0.3 0.3 -0.7 0.3 -0.6 0.0 -0.8 -1.1 0.0 -0.1 -0.3 -0.1 -0.2 -0.1 -0.1 0.1 -0.2 -0.8 -0.1 -0.0 -0.5 0.7 0.0 1.3 -0.0 -0.3 0.1
Basal cell carcinoma (self-reported) 0.2 0.2 1.2 0.1 0.7 0.8 -0.2 -0.2 0.1 0.5 0.3 0.2 1.1 0.4 0.5 0.9 -0.6 -0.2 0.6 0.6 -0.7 0.1 0.1 0.2 -1.0 -0.6 0.3 0.4 -0.3 -0.0 0.1 0.4 0.4 -0.2 -1.0 0.6 0.0 0.0 0.2 0.1 0.1 0.1 0.1 0.4 0.3
Heart attack/myocardial infarction (self-reported) 0.2 0.3 1.7 -0.4 -0.3 -0.0 -0.0 -0.7 0.6 -0.2 0.2 -0.9 0.3 -0.3 -0.0 -0.4 0.1 1.0 0.2 -0.6 0.1 0.1 -0.3 0.2 -0.5 0.4 -0.6 -0.4 -1.3 -0.7 -1.1 -0.5 -0.3 0.1 0.1 0.4 -0.3 -0.8 -1.0 -0.6 -0.7 -0.8 -0.9 -0.4 0.2
Deep venous thrombosis (DVT) (self-reported) 0.1 0.1 0.9 0.4 0.1 0.1 0.1 0.1 0.6 -0.3 -0.1 0.4 -0.2 0.7 0.1 0.4 -0.1 0.6 0.1 0.0 -0.6 -0.1 0.3 -0.0 0.3 0.1 0.0 0.2 -0.0 0.1 0.7 -0.1 -0.1 -0.2 0.1 0.0 -0.0 0.0 1.0 -0.5 -0.2 0.4 0.2 -0.1 -0.3
Heart disease (siblings) 0.2 0.2 3.1 1.0 0.3 0.2 1.8 0.7 1.2 0.1 0.5 0.4 0.3 0.2 0.0 0.1 -0.2 0.5 0.5 -0.1 1.1 -0.3 0.4 -0.2 0.1 -0.1 0.3 0.2 0.1 0.1 0.5 0.2 0.0 -0.3 -0.2 0.0 0.2 0.1 0.6 -0.3 -0.0 0.4 0.1 0.1 -0.1
Alcohol drinker status: Previous 1.1 1.3 2.7 -0.4 -1.1 -1.1 1.6 -0.1 0.7 -0.3 -1.1 -1.4 -1.6 -1.0 -1.3 -0.6 1.1 0.3 -0.6 -0.7 1.0 -1.5 -0.8 -0.8 1.2 -1.0 -1.3 -1.4 -1.3 -1.2 -0.4 -1.3 -1.5 -1.5 0.4 -1.1 -1.6 -1.3 -0.9 -1.4 -1.4 -1.5 -1.2 -1.3 -1.4
Pack years of smoking 1.1 1.5 6.3 -1.9 -0.6 -0.4 -2.5 -2.4 -1.6 -1.9 -0.2 -1.7 0.9 -1.1 0.3 -1.4 1.0 -0.8 -0.9 -1.4 -1.2 -1.1 -1.7 0.4 0.3 2.4 -0.6 -0.3 -1.5 -0.9 -1.6 -0.8 -0.1 1.0 1.5 -0.1 -0.4 -0.3 -1.7 -0.3 -0.6 0.8 -1.3 -1.5 1.3
Impedance of whole body 1.5 7.5 18.0 -1.8 -3.5 -3.6 -0.4 -0.9 0.9 -2.1 -2.6 -2.4 -3.0 -2.6 -3.2 -3.1 3.1 0.7 -3.3 -2.5 1.0 -2.8 -2.8 -3.3 4.2 -1.1 -3.1 -3.1 -1.4 -2.8 -2.4 -2.9 -3.1 -3.6 2.3 -3.1 -3.6 -2.3 -2.0 -2.8 -3.0 -3.4 -2.4 -2.8 -3.5
Leg fat mass (left) 0.1 0.5 4.4 -0.3 0.3 0.6 0.0 -0.9 0.5 -0.4 1.0 -0.5 0.7 -0.1 0.4 -0.7 0.4 -0.6 0.9 -0.1 1.4 0.1 -0.3 0.7 0.1 2.1 0.1 0.1 -0.9 -0.3 -0.3 -0.3 0.2 1.6 0.0 0.6 0.6 -0.3 -0.7 0.4 0.2 -0.3 -0.9 -0.3 1.4
Arm predicted mass (left) 0.9 4.4 11.4 1.1 2.5 2.8 0.2 0.7 -0.8 1.6 2.2 2.0 2.1 2.2 2.4 2.1 -1.9 -0.2 2.9 2.4 0.8 2.1 1.4 2.6 -2.7 1.5 2.4 2.2 1.5 2.1 1.6 2.1 2.4 3.4 -2.2 2.3 2.7 1.9 1.4 2.6 2.7 1.7 1.5 1.9 3.0