Hub : Genes

ENTPD5

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Aorta	0.2810	0.0740	0.00005	0.038	NA	0.029	NA	0.038	3.5e-03	NA	1.0e-02	NA	3.7e-03
2	GTEx	Brain Cerebellum	0.2190	0.0790	0.00100	0.244	NA	0.118	NA	0.217	7.7e-08	NA	2.4e-04	NA	4.7e-07
3	GTEx	Testis	0.1340	0.0650	0.00680	-0.006	NA	-0.006	NA	-0.005	8.4e-01	NA	7.4e-01	NA	6.5e-01
4	GTEx	Thyroid	0.0560	0.0280	0.00770	0.048	NA	0.033	NA	0.041	1.3e-04	NA	1.3e-03	NA	4.0e-04
5	YFS	Blood	0.0714	0.0171	0.00000	0.053	0.064	0.070	0.064	0.068	5.3e-17	3.8e-20	4.9e-22	3e-20	3.1e-21
6	TCGA	Kidney Renal Clear Cell Carcinoma	0.0536	0.0335	0.00950	0.014	0.013	0.015	NA	0.014	9.6e-03	1.0e-02	6.6e-03	NA	8.1e-03
7	TCGA	Liver Hepatocellular Carcinoma	0.1430	0.0620	0.00066	0.022	0.060	0.058	NA	0.051	3.3e-02	8.7e-04	1.0e-03	NA	2.0e-03
8	TCGA	Lung Squamous Cell Carcinoma	0.0178	0.0109	0.00680	0.004	0.006	-0.001	NA	0.000	9.4e-02	6.8e-02	4.9e-01	NA	3.1e-01

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	0.7	1.1	2.1	0.7	-1.4	-0.3	-1.1	1.4	0.8	-0.3	1.4
Bipolar Disorder or Schizophrenia	1.2	2.8	6.8	1.9	-1.3	-0.8	-1.3	2.6	1.7	-0.2	2.3
Depressed Affect (Nagel 2018)	0.5	1.0	3.4	-1.2	-0.3	1.8	-0.2	-1.4	-0.9	-0.6	-0.1
Depression (Nagel 2018)	0.1	0.2	0.6	-0.6	-0.1	0.6	0.1	-0.2	-0.3	-0.8	-0.2
Intelligence (Savage-Jansen 2018)	0.5	1.4	5.6	-0.5	0.5	-1.1	0.5	2.4	1.6	1.2	0.2
Neuroticism (Nagel 2018)	0.2	0.5	1.5	-1.0	-1.2	-0.1	-0.9	0.4	0.2	0.1	-0.4
Schizophrenia (2018)	0.9	1.9	5.1	1.7	-0.5	-0.8	-0.8	2.3	1.5	0.0	1.8
Schizophrenia vs Biploar Disorder	1.6	2.1	5.0	0.6	1.6	1.0	1.3	-2.2	-1.9	-0.4	-1.6
Worry (Nagel 2018)	0.4	0.9	2.7	-0.1	-0.4	-1.5	-0.1	0.9	0.0	1.0	-1.6
Alzheimer’s Disease (in mother)	0.7	0.8	2.2	-1.1	-0.3	1.5	-0.0	-0.4	1.2	1.0	-0.1
Alzheimer’s Disease (in father)	1.8	1.9	5.3	-0.1	2.3	-0.1	2.3	-0.4	-0.9	1.0	-1.7
Alzheimer’s Disease (including proxy)	1.5	2.1	5.3	-0.3	2.3	1.0	2.3	-1.0	0.1	1.3	-1.7
Crohns Disease (2017)	0.1	0.2	1.0	0.2	1.0	-0.5	0.5	0.4	-0.1	0.5	0.2
Irritable Bowel Disease (IBD)	0.1	0.2	0.8	-0.9	-0.3	0.4	-0.4	-0.4	-0.0	-0.2	0.7
Ulcerative Colitis (UC)	0.6	1.1	2.7	-1.7	-1.3	1.0	-1.0	-1.1	0.0	-0.8	0.9
Major Depression (MDD)	0.2	0.2	0.4	0.5	0.3	0.6	0.7	0.1	-0.2	-0.4	-0.6
Reaction Time	0.6	1.2	4.6	-0.8	-0.1	1.4	-0.1	-2.1	-1.5	-0.2	-0.1
Verbal and Numeric Reasoning (VNR)	0.6	1.4	5.6	-1.3	-0.1	-1.3	-0.2	2.4	1.1	0.8	0.1
Breast Cancer	0.3	0.6	1.3	-0.9	0.9	-0.9	1.0	0.1	-0.4	-0.1	-1.1
Ovarian Cancer	1.8	2.4	10.5	1.3	0.7	1.6	0.4	-3.2	-1.8	-0.2	-0.4
Prostate Cancer	0.8	1.1	3.8	-1.9	-1.5	0.1	-1.2	-0.3	-0.4	-0.0	0.9
Age at First Birth	1.3	1.8	4.6	-2.1	-0.3	-1.4	-0.2	2.1	1.4	1.0	-0.8
Bipolar Disorder (2011)	1.3	1.3	3.6	0.5	-0.7	-1.2	-0.5	1.9	1.4	1.0	1.1
Body Mass Index (BMI) (2010)	1.7	2.4	5.9	2.2	0.7	1.8	0.1	-2.4	-1.8	-0.7	1.1
Coronary Artery Disease (CAD)	0.4	0.5	1.0	1.0	0.9	-1.0	0.9	-0.2	0.3	0.5	-0.5
Crohns Disease (2012)	0.3	0.5	1.8	0.3	0.0	-0.3	-0.2	0.8	1.2	1.3	0.4
Mean Putamen Volume	0.8	0.9	3.2	-0.1	-0.0	-1.2	-0.0	-0.3	-1.8	-1.3	-0.7
Fasting Glucose	0.9	1.0	3.3	1.8	-0.4	-0.4	-0.8	0.4	-0.2	-1.3	1.4
HbA1C	0.2	0.3	1.2	0.8	-0.2	-1.1	-0.0	-0.2	-0.0	0.2	-0.3
HDL Cholesterol	0.3	0.6	1.3	-0.9	-1.0	0.7	-0.7	-0.5	1.1	0.1	0.1
LDL Cholesterol	1.2	1.9	6.3	0.9	-0.3	-0.9	-0.7	1.1	-1.8	-2.5	1.3
Lupus	0.4	0.6	2.1	-0.8	0.4	0.2	0.6	-0.6	-1.4	-0.8	-0.8
Neuroticism (2016)	0.2	0.2	0.6	-0.0	-0.2	0.3	-0.4	-0.6	-0.8	-0.7	-0.2
Primary Biliary Cirrhosis	0.9	1.3	5.9	-0.6	-2.4	0.2	-1.9	-0.3	-0.3	-0.4	0.3
Rheumatoid Arthritis	0.7	0.9	3.6	-0.3	-0.3	1.5	-0.7	-0.7	-0.6	-0.1	1.9
Schizophrenia (2014)	0.7	1.5	6.3	2.5	-0.7	0.0	-0.8	1.1	0.9	-0.0	1.5
Triglycerides	0.6	1.0	2.2	-1.4	-0.9	0.8	-1.1	0.3	-1.0	-0.5	1.5
Type 2 Diabetes (T2D) (2012)	1.0	1.1	4.3	0.6	1.2	-0.3	0.8	-0.7	-2.1	-0.8	-1.0
Ulcerative Colitis	0.8	1.2	3.1	-1.2	-1.8	0.5	-1.6	-0.4	0.5	-0.5	1.1
Blood Eosinophil Count	0.1	1.0	2.6	0.1	0.6	1.5	0.4	-1.6	-1.2	-0.8	0.6
Blood Platelet Count	0.9	10.2	22.9	4.0	4.8	0.4	4.5	-2.9	-1.0	1.1	-3.4
Blood Red Count	1.0	9.5	30.8	-0.9	-4.8	-1.2	-5.6	0.8	-2.1	-0.6	3.8
Blood White Count	0.5	3.5	8.5	-1.0	0.0	2.9	-0.5	-2.1	-2.2	-2.3	1.9
Heel T-Score	0.3	2.0	7.3	-0.9	2.7	-0.9	1.6	1.2	-1.3	0.5	-1.1
BMI	0.8	4.5	9.6	-0.3	0.5	2.7	-0.0	-3.1	-3.1	-2.6	1.7
Height	0.4	8.0	34.7	2.5	2.2	-1.4	3.5	-1.6	0.0	1.1	-5.9
Waist Hip Ratio (WHR)	0.8	3.5	11.2	3.3	1.4	-1.3	1.7	-1.3	0.8	1.4	-2.5
Systolic Blood Pressure	0.2	0.9	1.7	-0.8	-1.1	-0.8	-1.3	-1.3	-1.0	-0.1	0.5
Smoking Status	0.1	0.3	0.5	-0.0	0.5	0.2	0.7	-0.4	-0.7	-0.6	-0.5
Allergy or Eczema	0.2	0.6	2.0	0.4	0.0	0.9	0.4	-0.5	1.1	1.4	-0.3
Cardiovascular Disease	0.7	2.3	7.3	1.8	0.8	-0.3	0.2	-1.6	-2.7	-2.0	0.8
Hypothyroidism (self reported)	0.2	0.5	2.2	1.5	0.7	-0.6	0.5	0.8	0.0	-0.3	0.2
Respiratory disease	0.3	0.6	1.1	0.5	0.8	0.7	1.0	-1.0	-0.3	0.7	-1.0
Type 2 Diabetes (T2D) (2018)	0.6	1.0	4.3	-0.1	0.3	0.3	-0.1	-0.6	-1.6	-2.1	1.0
Lung FEV1/FVC ratio	2.1	10.8	25.7	-2.8	-4.5	0.6	-4.9	2.2	0.7	-1.6	5.1
Lung FVC	0.4	2.2	4.4	2.1	-1.7	-0.3	-1.9	1.7	1.0	1.3	1.2
Neuroticism	0.1	0.3	1.0	-0.7	-0.7	1.0	-0.6	-0.4	-0.4	-0.2	0.1
Chronotype (morning person)	1.6	3.6	9.3	2.1	2.5	-0.7	2.7	-0.4	-0.8	-0.8	-3.0
Hair Pigment	0.0	1.1	3.6	1.1	-0.2	-1.9	-0.3	1.6	1.2	0.2	-0.1
Tanning	0.1	0.9	2.0	-0.1	0.6	1.3	1.0	-1.1	0.4	1.1	-1.4
Hand grip strength (left)	1.1	2.8	7.6	-0.7	0.9	1.4	1.6	-1.2	1.9	2.8	-1.9
Number of treatments/medications taken	1.4	2.6	6.2	0.6	2.5	0.4	2.2	-1.6	-2.2	-1.0	-1.0
Average weekly spirits intake	1.1	1.3	3.4	1.5	1.8	-0.5	1.5	-0.5	-0.8	-0.2	-1.3
Sensitivity / hurt feelings	0.8	1.4	3.3	1.1	-1.6	0.2	-1.8	0.7	0.1	-1.1	1.4
Frequency of depressed mood in last 2 weeks	0.3	0.4	2.0	-1.4	0.2	0.5	-0.1	0.2	-0.8	-0.6	-0.1
Hearing difficulty/problems: Yes	0.4	0.6	1.7	1.3	-1.3	-0.4	-1.0	-0.8	0.1	0.3	-0.0
Relative age of first facial hair	0.7	1.4	3.8	0.8	-1.5	-0.1	-1.6	0.1	-0.1	-1.4	2.0
Other serious medical condition/disability diagnosed by doctor	1.2	1.5	5.0	2.2	1.0	-1.5	0.5	0.7	-1.6	-0.9	-0.0
Ever used hormone-replacement therapy (HRT)	0.6	0.7	1.6	1.3	-1.2	-0.0	-0.8	-0.8	-0.6	-1.0	0.0
Ever had hysterectomy (womb removed)	2.4	2.7	4.8	-1.8	-2.2	-0.1	-2.1	2.2	1.1	-0.3	1.8
Systolic blood pressure, automated reading	0.3	0.9	2.3	-1.2	-1.5	-0.4	-1.5	-0.4	0.1	0.1	0.9
Eye problems/disorders: Diabetes related eye disease	0.5	0.6	1.3	0.9	-0.7	-0.7	-1.0	0.2	0.1	0.6	1.2
Angina	1.1	1.4	2.9	-0.1	1.6	0.7	1.7	-1.5	-1.0	0.4	-1.5
Medication for hormone replacement therapy	2.6	2.9	8.5	-1.3	-2.9	0.7	-2.4	-0.3	-0.5	-1.9	1.7
Vitamin and mineral supplements	2.4	3.3	11.4	1.4	0.9	0.1	0.2	-0.8	-3.1	-3.4	1.2
Supplements: Zinc	0.9	1.0	4.6	-0.9	0.7	2.1	1.1	-0.6	0.2	0.3	-0.7
Medication: Co-codamol	0.5	0.5	2.2	-0.3	1.5	0.1	0.9	0.3	-0.7	-0.7	0.4
Medication: Metformin	0.9	1.3	3.6	-0.4	-0.9	0.7	-0.8	-1.3	-1.6	-1.9	0.8
Diabetes (father)	0.2	0.3	0.8	-0.7	0.1	-0.2	0.0	0.2	0.7	0.9	-0.3
Diabetes (mother)	0.7	1.0	2.7	-0.4	-0.6	0.3	-0.8	0.2	-1.2	-1.7	1.5
Severe depression (siblings)	0.7	0.8	1.7	-0.9	-1.3	-0.7	-1.2	0.1	-0.8	-1.0	0.4
Pack years adult smoking proportion	0.7	1.0	2.1	0.7	0.5	1.1	0.7	-1.2	-1.5	-1.3	-0.1
Impedance of leg (right)	1.1	5.1	15.4	2.1	0.5	-3.9	1.1	2.4	2.0	1.1	-2.9
Leg fat-free mass (left)	0.5	2.5	7.6	-0.9	-0.2	2.2	-0.2	-2.8	-2.0	-1.5	0.9
Trunk fat percentage	0.6	2.4	8.5	0.4	0.9	-0.2	0.6	-1.9	-2.9	-2.4	-0.1
Hand grip strength (right)	0.9	2.5	5.6	-0.2	0.6	1.6	1.4	-1.2	2.3	2.4	-1.5
Townsend deprivation index at recruitment	0.9	1.2	3.0	0.1	-0.2	1.7	-0.4	-0.9	-1.4	-1.7	1.1
Current tobacco smoking	0.3	0.5	1.1	0.8	-0.3	1.0	-0.5	-0.5	-0.6	-0.8	1.0
Average weekly fortified wine intake	2.1	2.5	4.5	0.3	1.9	-0.9	2.0	0.9	1.4	2.1	-2.0
Maternal smoking around birth	0.1	0.2	1.0	0.2	-0.2	0.1	-0.0	-0.2	-1.0	-0.2	-0.3
Fed-up feelings	0.7	1.4	4.5	-2.0	-0.0	2.1	0.2	-1.3	-0.1	0.5	-0.6
Frequency of unenthusiasm / disinterest in last 2 weeks	0.8	1.1	2.2	-0.5	-1.2	1.1	-1.2	-0.5	-1.0	-1.5	1.0
Relative age voice broke	0.7	1.0	3.8	1.9	-0.7	0.6	-0.5	-0.3	-0.1	-1.0	1.5
Taking other prescription medications	0.6	0.9	2.5	0.6	1.2	-0.9	1.0	-0.2	-1.6	-0.6	-0.6
Age when periods started (menarche)	0.1	0.4	1.9	-0.2	-0.0	-0.8	-0.2	1.4	0.0	-0.2	0.2
Bilateral oophorectomy (both ovaries removed)	1.3	1.4	3.9	-1.3	-2.0	1.3	-1.4	-0.9	-0.2	-1.1	0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.1	3.6	-0.3	0.6	-1.5	0.4	1.9	0.5	1.3	-0.7
Tinnitus: Yes, but not now, but have in the past	0.4	0.5	1.1	-0.9	-0.3	0.9	-0.5	-0.6	-0.4	-1.0	0.5
Qualifications: CSEs or equivalent	0.2	0.3	1.0	-0.9	-0.2	-1.0	-0.6	0.6	-0.3	0.2	0.3
Serious illness, injury or assault to yourself	0.5	0.6	1.3	-0.7	0.4	1.1	0.5	-0.9	-1.0	-0.6	0.5
High blood pressure	0.3	0.8	2.2	0.6	1.1	0.2	0.7	-1.3	-1.5	-0.7	0.4
Hayfever, allergic rhinitis or eczema	0.3	0.6	1.7	0.7	-0.5	1.3	-0.3	-1.2	0.1	0.5	0.5
Multivitamins +/- minerals	1.9	2.4	8.3	-1.9	-0.5	0.3	-0.0	0.4	2.4	2.9	-1.2
Stomach or abdominal pain in last month	0.6	0.7	5.0	-2.2	0.1	0.2	0.3	0.1	0.2	0.7	-0.3
Supplements: Glucosamine	0.4	0.5	1.3	-0.8	-0.6	1.0	-0.2	-1.1	0.4	0.1	-0.6
Diverticular disease/diverticulitis (self-reported)	1.4	1.7	5.6	0.2	2.4	-0.8	1.9	-0.2	-0.8	0.9	-1.5
Medication: Atenolol	1.6	2.0	3.9	0.9	1.9	0.2	1.7	-1.8	-2.0	-1.0	-0.8
Medication: Levothyroxine sodium	0.4	0.8	3.1	1.2	0.3	-1.8	0.1	1.1	0.1	-0.3	-0.4
Sitting height	0.1	0.7	2.9	0.1	-1.7	-0.3	-0.9	0.1	1.0	-0.4	-0.7
Chronic bronchitis/emphysema (father)	0.3	0.4	1.2	0.2	0.0	-0.4	0.5	0.9	0.6	1.1	-0.5
High blood pressure (mother)	1.0	1.4	5.6	-1.0	1.3	0.0	0.4	-1.3	-2.4	-1.1	0.2
Body mass index (BMI)	0.9	3.6	9.0	-1.0	-0.3	1.7	-0.8	-2.2	-3.0	-2.7	1.9
Impedance of leg (left)	0.9	4.4	12.7	2.2	0.8	-3.6	1.1	2.2	1.7	0.9	-2.7
Leg predicted mass (left)	0.5	2.6	7.9	-1.0	-0.1	2.3	-0.1	-2.8	-2.0	-1.5	0.8
Trunk fat mass	0.6	2.7	9.5	0.2	0.6	0.3	0.4	-2.2	-3.1	-2.6	0.1
Waist circumference	0.6	2.3	6.4	0.4	0.1	0.7	-0.1	-2.4	-2.5	-2.3	0.6
Number of incorrect matches in round	0.5	0.8	1.9	-1.1	-1.4	-0.3	-1.2	1.0	0.4	-0.1	0.6
Past tobacco smoking	0.2	0.4	2.3	1.5	0.1	-0.2	-0.3	0.4	0.1	0.4	0.5
Alcohol usually taken with meals	1.1	1.8	3.9	-1.5	-1.3	1.9	-1.4	-0.7	0.6	-0.0	2.0
Nervous feelings	0.5	0.9	1.7	0.3	-1.3	-0.7	-1.3	1.2	1.0	0.6	0.4
Frequency of tenseness / restlessness in last 2 weeks	0.7	1.1	3.0	-1.1	-0.4	0.9	-0.3	-1.6	-1.7	-1.1	-0.2
Hearing difficulty/problems with background noise	0.6	0.9	2.8	-0.5	-1.7	-0.4	-1.6	0.3	0.6	0.7	0.8
Hair/balding pattern: Pattern 2	0.6	0.7	1.9	0.4	0.4	-0.4	0.7	0.6	1.4	1.3	-1.0
Had menopause	1.3	1.6	8.0	2.8	0.2	-1.6	0.7	-0.4	-0.5	-0.2	-1.1
Had other major operations	1.6	1.9	8.6	0.7	-0.2	2.9	-0.2	-2.2	-0.5	0.1	0.9
Forced vital capacity (FVC)	0.2	0.8	2.0	1.1	-1.4	-0.2	-1.1	0.3	1.3	0.7	-0.1
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.6	1.5	-0.3	1.1	-0.8	0.8	1.2	-0.1	0.7	-0.2
Ever unenthusiastic/disinterested for a whole week	1.0	1.3	3.3	-0.6	-1.8	1.2	-1.6	0.1	0.6	-0.4	1.4
Qualifications: None of the above	2.4	5.1	9.1	3.0	1.7	0.7	2.1	-2.7	-2.6	-2.0	-2.4
Financial difficulties in last 2 years	0.3	0.4	1.6	-0.5	0.8	0.4	0.4	-0.0	-1.3	0.4	-0.3
Mouth/teeth dental problems	0.5	0.8	2.3	0.3	-1.2	-0.4	-1.0	0.8	1.5	0.2	0.8
Heart attack	0.5	0.6	2.3	-0.3	-0.2	1.3	-0.0	-1.5	-0.3	-0.7	0.4
Allergy	0.3	0.8	2.2	-1.5	-0.3	-1.0	-0.4	1.2	-0.3	-1.1	0.2
Pain all over the body in last month	0.3	0.3	1.4	1.2	-0.0	-0.1	0.2	-0.2	-0.1	-0.8	0.5
Diabetes (self-reported)	1.3	2.0	5.9	-0.6	-1.0	1.2	-1.0	-1.2	-1.4	-2.4	1.7
Hayfever/allergic rhinitis (self-reported)	0.2	0.3	0.7	0.8	0.2	-0.0	0.6	0.1	0.7	0.7	-0.6
Medication: Ramipril	0.9	1.2	3.2	1.8	1.1	-0.4	1.0	-1.5	-1.0	-0.7	-0.3
Medication: Simvastatin	0.5	0.8	1.8	-0.7	-1.0	1.0	-0.8	-0.2	-0.3	-1.1	1.3
Fluid intelligence score	0.4	0.9	2.3	-1.3	-0.2	-0.5	-0.1	1.5	1.3	1.0	0.2
Illnesses of siblings	0.6	0.9	2.8	-1.7	0.1	1.4	0.2	-1.3	-0.3	-0.2	-0.4
Neuroticism score	0.3	0.7	1.6	-1.1	-1.2	0.3	-1.3	0.8	0.2	0.1	0.4
Weight	0.5	2.7	7.6	-0.0	0.3	1.5	0.3	-2.7	-2.6	-2.1	0.4
Impedance of arm (right)	1.1	5.0	10.0	2.2	2.5	-3.2	2.4	1.6	0.7	1.4	-2.8
Arm fat percentage (right)	0.7	2.7	10.8	-0.2	1.0	0.3	0.4	-1.4	-3.3	-2.6	0.9
Trunk fat-free mass	0.3	1.4	5.0	-0.4	-0.4	2.1	-0.0	-2.2	-0.9	-0.9	0.1
Hip circumference	0.5	2.2	6.6	0.0	-0.1	1.2	-0.2	-1.7	-2.2	-2.6	1.5
Time employed in main current job	0.4	0.5	1.3	-0.8	-1.2	-0.5	-1.0	0.5	0.2	-0.5	0.4
Alcohol intake versus 10 years previously	0.7	1.1	2.9	1.7	0.4	0.1	0.3	-0.6	-1.5	-1.5	0.8
Father’s age at death	0.4	0.5	2.8	0.2	-0.2	0.6	0.2	0.1	1.7	0.8	-0.2
Worrier / anxious feelings	0.2	0.4	1.5	-1.2	-0.8	-0.5	-0.6	0.7	-0.1	0.6	-0.1
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.8	2.7	0.1	0.1	1.6	0.2	-0.8	-0.9	-1.4	0.6
Falls in the last year	1.0	1.4	4.5	0.4	2.0	-0.5	2.1	-0.6	-0.5	0.2	-1.3
Hair/balding pattern: Pattern 3	0.7	1.0	2.9	1.7	1.3	0.3	0.9	-0.7	-1.2	-0.9	0.3
Number of live births	1.2	1.6	6.0	0.1	-0.7	2.4	-0.4	-1.6	-1.4	-1.1	0.9
Forced expiratory volume in 1-second (FEV1)	0.7	2.5	6.9	-0.0	-2.6	-0.5	-2.5	1.3	1.4	0.4	1.4
Pulse rate	0.4	0.6	1.3	-0.9	-1.1	0.5	-1.1	-0.1	-0.1	-0.4	1.1
Happiness	2.3	2.8	5.3	-2.1	-2.3	-0.2	-2.1	1.8	1.6	0.8	1.3
Noisy workplace	0.4	0.5	2.7	1.6	-0.7	0.1	-0.7	0.1	0.1	-0.0	0.4
Qualifications: A levels/AS levels or equivalent	0.4	0.9	3.1	-0.2	1.0	0.7	0.7	0.6	1.3	1.8	-0.0
Serious illness, injury or assault of a close relative in last 2 years	1.0	1.1	4.2	-1.6	-0.7	2.0	-0.6	-0.7	0.1	0.2	0.9
Mouth/teeth dental problems: Dentures	0.7	1.2	3.8	0.3	-0.6	0.8	-0.8	-0.3	-1.4	-2.0	1.3
Asthma	0.9	1.9	3.9	0.9	2.0	0.4	1.9	-0.6	0.7	2.0	-1.4
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	1.6	-0.4	0.2	1.3	-0.0	-0.7	-0.6	-0.9	0.7
Medication: Cholesterol lowering	0.9	1.5	3.7	-1.3	-0.7	0.2	-1.1	-0.2	-1.6	-1.9	1.3
Depression (self-reported)	0.6	0.7	1.3	-0.0	1.2	-1.1	0.4	1.0	-1.1	-0.4	-0.4
Medication: Lansoprazole	1.2	1.4	4.0	-2.0	0.9	-0.1	1.4	-0.4	-0.4	0.5	-1.9
Prospective memory result	0.2	0.3	1.1	0.0	-0.0	0.4	-0.2	-0.6	-1.1	-0.8	0.3
Lung cancer (father)	0.8	1.0	1.9	-0.9	-1.3	-1.2	-1.2	1.4	-0.3	-0.4	0.4
Illnesses of mother	0.5	0.6	2.2	-0.6	-0.9	-0.0	-0.3	1.0	1.5	0.4	-0.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.9	2.9	8.8	-0.6	-2.9	-0.2	-3.0	1.2	1.0	0.1	1.8
Pulse wave Arterial Stiffness index	0.9	1.0	3.5	1.2	1.0	-0.5	1.2	-0.5	0.0	0.7	-1.9
Impedance of arm (left)	0.8	3.5	7.4	1.6	2.0	-2.7	2.0	1.2	0.6	1.1	-2.7
Arm fat mass (right)	0.7	2.8	9.5	-0.1	0.3	0.9	-0.0	-2.0	-3.1	-2.7	0.9
Trunk predicted mass	0.3	1.4	4.8	-0.4	-0.4	2.1	-0.1	-2.2	-0.9	-1.0	0.1
Standing height	0.3	2.5	9.0	1.9	1.0	-0.5	1.9	-1.2	0.6	0.7	-3.0
Length of working week for main job	0.3	0.4	0.8	0.2	0.9	-0.2	0.9	-0.2	-0.7	0.4	-0.7
Exposure to tobacco smoke at home	1.7	1.9	8.7	3.0	-0.3	0.8	-0.3	-1.8	-1.4	-0.6	0.2
Breastfed as a baby	1.0	1.3	2.8	1.4	1.6	-0.6	1.7	-0.3	-0.6	0.3	-1.3
Tense / ‘highly strung’	0.7	1.1	4.3	-0.2	0.9	0.3	1.5	0.1	0.8	0.9	-2.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.5	1.5	0.7	-0.5	-0.5	-0.4	0.8	-1.0	-1.2	0.0
Hair/balding pattern: Pattern 4	1.0	2.4	5.5	-2.3	-1.5	2.1	-1.5	-1.2	-0.7	-0.7	1.4
Birth weight of first child	0.3	0.6	1.7	-1.3	-0.3	-0.8	-0.6	1.1	0.1	-0.5	0.5
Peak expiratory flow (PEF)	2.7	6.4	16.8	-2.5	-3.9	-0.5	-4.1	1.3	-0.1	-1.3	2.9
Pulse wave reflection index	2.5	3.1	7.1	1.9	1.6	-1.5	1.9	0.9	1.2	1.8	-2.7
Ever highly irritable/argumentative for 2 days	0.1	0.1	0.4	0.5	-0.1	0.2	-0.1	0.5	-0.3	-0.3	0.6
Loud music exposure frequency	1.0	1.1	2.6	-0.3	-1.2	0.2	-1.3	0.3	-0.8	-1.5	1.6
Qualifications: O levels/GCSEs or equivalent	1.1	1.7	3.8	-1.6	-0.6	-0.5	-0.9	1.9	1.8	1.2	1.3
Mouth/teeth dental problems: Bleeding gums	0.2	0.3	1.4	-0.2	0.5	0.5	0.1	-1.2	-0.3	0.6	-0.4
Blood clot in the leg (DVT)	0.1	0.1	0.3	-0.1	-0.1	0.0	-0.2	0.2	-0.6	0.2	0.5
Medication: Paracetamol	0.3	0.5	1.4	0.7	0.9	0.0	0.2	-0.2	-1.2	-0.6	1.0
Headache pain in last month	0.2	0.4	0.7	0.3	0.8	0.4	0.8	-0.8	-0.1	0.8	-0.2
Medication for cholesterol, blood pressure or diabetes	0.9	1.4	5.0	0.9	-0.3	0.5	0.1	0.5	2.2	2.2	-0.7
Glaucoma (self-reported)	0.9	1.1	2.6	-1.6	-1.5	0.4	-1.3	0.4	0.7	0.4	0.9
Gout (self-reported)	1.0	1.4	3.1	-0.4	-1.8	-0.6	-1.7	1.1	-0.7	-1.0	1.4
Hypothyroidism/myxoedema (self-reported)	0.3	0.6	1.7	1.3	0.5	-1.3	0.3	1.1	0.0	-0.4	-0.1
Medication: Amlodipine	0.6	0.8	2.3	-1.4	0.1	-0.1	-0.1	-1.1	-1.5	-0.9	0.2
Medication: Ventolin 100micrograms inhaler	0.2	0.3	0.6	-0.6	0.8	-0.6	0.7	0.6	-0.3	0.2	-0.4
Birth weight	3.4	7.5	18.2	-0.2	-3.8	0.3	-4.2	0.7	-1.4	-2.7	4.3
Chronic bronchitis/emphysema (mother)	1.6	1.9	6.4	2.5	-0.2	1.0	0.6	-2.3	0.3	0.4	-1.3
High blood pressure (siblings)	0.5	0.7	2.0	0.8	-0.5	-1.4	-0.9	1.3	-0.4	-0.0	0.5
Forced vital capacity (FVC), Best measure	0.2	0.7	2.1	0.6	-1.4	0.1	-1.3	0.2	1.0	0.6	0.4
Body fat percentage	0.6	2.5	9.2	0.1	0.7	-0.1	0.4	-1.7	-3.0	-2.7	0.2
Leg fat percentage (right)	0.7	2.7	10.3	0.0	-0.2	-0.3	-0.4	-1.4	-2.9	-3.2	0.5
Arm fat-free mass (right)	0.3	1.5	4.5	-0.7	-0.8	2.0	-0.5	-2.1	-0.9	-1.1	0.6
Exposure to tobacco smoke outside home	1.1	1.5	4.2	2.1	0.9	1.4	0.7	-1.6	-1.0	0.8	-0.5
Comparative body size at age 10	0.4	1.1	2.9	-1.7	1.5	-0.3	0.8	-0.4	-1.6	0.2	-0.2
Number of full brothers	0.5	0.6	2.1	-1.2	-0.3	-0.5	-0.3	1.5	0.8	0.4	0.5
Worry too long after embarrassment	2.0	3.3	6.9	-0.9	-2.6	-1.0	-2.6	2.2	0.9	-0.3	2.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	1.5	0.0	-0.6	-0.7	-0.6	1.2	0.3	-0.4	0.3
Wheeze or whistling in the chest in last year	1.3	2.3	6.6	0.3	2.3	0.6	2.6	-1.4	-0.5	0.6	-2.0
Number of children fathered	3.6	4.1	7.3	-2.5	-2.1	1.9	-2.1	-1.0	-1.0	-2.1	2.7
Reason for reducing amount of alcohol drunk: Health precaution	0.9	1.1	4.0	-0.8	1.0	0.1	1.3	-0.1	0.7	0.8	-2.0
Age at first live birth	0.6	1.1	4.5	-2.1	-0.1	-0.9	0.4	0.6	1.3	0.8	-0.9
Pulse wave peak to peak time	0.6	0.7	2.2	-1.0	-0.7	0.5	-0.9	0.2	-0.1	-0.8	1.5
Health satisfaction	2.9	3.7	12.0	-1.3	-1.9	3.5	-1.5	-2.6	0.2	-0.2	1.9
Shortness of breath walking on level ground	0.3	0.3	0.8	-0.9	-0.3	0.7	-0.1	0.5	0.5	-0.6	0.7
Qualifications: College or University degree	1.2	3.8	10.8	-3.3	-1.1	-0.3	-1.7	2.7	1.8	1.0	2.0
Eye problems/disorders: None of the above	1.3	1.5	4.5	0.5	1.4	-0.4	1.5	-0.8	0.3	1.6	-2.1
Mouth/teeth dental problems: Loose teeth	1.5	1.8	4.2	1.9	1.6	-0.5	1.7	-0.7	-0.4	0.6	-2.0
Emphysema/chronic bronchitis	0.5	0.6	1.9	1.4	0.4	0.3	0.2	-0.0	-0.4	-0.9	1.3
Medication for pain relief, constipation, heartburn	0.6	1.1	2.9	-1.2	-1.0	-0.7	-0.7	0.8	1.7	1.2	-0.5
Neck or shoulder pain in last month	0.4	0.6	1.7	1.3	-0.5	-0.0	-0.2	-0.5	-1.0	-1.2	0.0
Medication: Blood pressure	0.6	1.0	2.8	-1.0	1.0	-0.3	0.7	-1.0	-1.7	-1.2	-0.0
Angina (self-reported)	0.9	1.2	2.2	-0.1	1.3	0.5	1.5	-1.4	-1.1	0.2	-1.5
Migraine (self-reported)	0.3	0.3	1.0	0.2	0.5	0.7	0.4	-0.3	0.8	1.0	0.5
Medication: Ibuprofen	0.5	0.6	2.8	-0.5	0.0	1.7	0.0	-1.0	-0.1	-0.5	0.6
Medication: Allopurinol	0.8	1.0	3.2	-1.0	-0.7	0.5	-1.0	-0.3	-1.8	-1.2	0.9
Medication: Omeprazole	1.0	1.2	3.4	-0.3	-1.4	1.0	-1.4	-0.2	-0.4	-1.0	1.8
Medication: Seretide 50 evohaler	0.4	0.4	0.8	-0.1	-0.7	0.6	-0.8	-0.3	-0.6	-0.9	0.7
Mean time to correctly identify matches	0.7	1.3	5.0	-0.6	0.4	1.2	0.4	-2.2	-1.7	-0.2	-0.5
Heart disease (mother)	0.3	0.3	1.4	0.3	1.2	-0.1	0.8	0.0	-0.1	0.7	-0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	1.1	0.2	1.0	-0.5	0.8	-0.7	-1.0	0.5	-1.0
Whole body fat mass	0.7	3.1	10.4	0.0	0.3	0.4	0.0	-2.1	-3.2	-3.0	0.6
Leg fat mass (right)	0.7	2.5	8.7	-0.0	-0.2	0.1	-0.4	-1.7	-2.8	-3.0	0.8
Arm predicted mass (right)	0.3	1.6	3.7	-0.8	-1.1	1.9	-0.9	-1.9	-0.8	-1.2	0.9
Pulse rate, automated reading	1.6	5.0	13.8	0.0	-3.7	1.8	-3.3	-1.3	-0.2	-1.4	3.0
Alcohol intake frequency.	1.4	3.3	6.7	1.8	-0.9	1.4	-1.3	-1.2	-2.5	-2.6	2.1
Comparative height size at age 10	1.2	6.4	17.2	1.7	3.0	-1.5	3.7	-0.2	1.2	2.2	-4.2
Number of full sisters	1.7	2.0	7.1	-0.9	0.2	1.7	-0.1	-0.9	-2.7	-2.0	0.7
Suffer from ‘nerves’	0.7	1.1	3.9	-0.3	-0.1	-0.9	0.2	1.1	1.3	2.0	-1.2
Overall health rating	1.8	3.8	8.5	0.1	-0.6	2.0	-1.1	-1.8	-2.7	-2.9	2.4
Chest pain or discomfort	0.3	0.5	2.3	1.5	0.5	0.2	0.3	-0.5	-0.7	-0.3	0.3
Had major operations	1.4	1.7	4.2	-2.0	-1.4	1.2	-1.1	-0.5	-0.8	-1.4	1.4
Age at last live birth	0.1	0.1	0.4	-0.6	0.1	0.4	0.2	-0.3	-0.0	0.2	-0.4
Family relationship satisfaction	0.9	1.1	3.5	-0.2	-1.9	1.2	-1.6	-0.5	0.2	0.5	0.7
Leg pain on walking	0.2	0.3	1.1	0.2	-0.3	1.1	0.0	-0.7	0.6	0.3	0.3
Qualifications: NVQ or HND or HNC or equivalent	0.6	0.8	2.4	0.5	1.6	0.1	1.4	-0.4	-0.6	-0.7	-0.7
Commuting to job workplace: Car/motor vehicle	0.6	0.7	2.9	-0.3	1.1	1.7	0.9	-0.7	-0.1	0.5	0.1
Illness, injury, bereavement, stress in last 2 years	0.7	0.8	2.8	-0.5	0.0	-1.7	-0.1	1.2	1.3	0.3	-0.4
Medication: Aspirin	0.8	1.0	2.4	1.3	1.0	0.2	1.5	-1.0	-0.6	0.0	-1.2
Supplements: Vitamin C	0.4	0.5	1.9	0.6	-0.6	-0.3	-0.2	0.5	1.4	0.9	-0.3
Knee pain experienced in last month	1.2	1.9	3.7	1.9	1.6	-1.1	1.8	-0.8	-0.2	0.1	-1.8
Hypertension (Self-reported)	0.3	0.8	2.1	0.9	0.9	0.1	0.6	-1.5	-1.3	-0.6	0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.8	2.0	-0.6	-0.7	-1.3	-1.1	1.4	0.6	0.5	0.6
Illnesses of father: Heart disease	0.6	0.8	2.1	-0.8	0.7	-0.7	0.5	0.9	1.4	1.2	0.1
Illnesses of siblings: Diabetes	0.4	0.5	1.6	-0.1	-0.6	0.4	-0.9	0.8	-0.2	-0.7	1.2
Smoking status: Previous	0.5	0.7	2.2	-1.5	-1.1	-0.8	-0.7	0.4	0.2	-0.8	0.1
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.5	2.1	-0.2	0.2	-0.6	0.3	0.5	1.4	0.4	-0.8
Whole body fat-free mass	0.4	2.1	6.7	-0.6	-0.4	2.4	-0.2	-2.6	-1.4	-1.2	0.5
Leg fat-free mass (right)	0.5	2.8	8.2	-0.9	-0.1	2.6	-0.1	-2.9	-2.0	-1.4	1.0
Arm fat percentage (left)	0.8	3.1	11.4	-0.7	0.6	0.8	0.1	-1.7	-3.4	-2.8	1.2
Average weekly red wine intake	0.9	1.3	3.1	-1.3	0.9	-1.8	0.6	1.3	1.0	1.0	-0.8
Handedness (chirality/laterality): Left-handed	0.7	0.8	2.4	-1.2	-0.6	-1.2	-0.7	1.5	-0.1	-0.6	0.3
Mood swings	0.8	1.5	3.2	-1.8	-1.0	1.3	-1.1	-0.9	-1.5	-1.3	0.5
Loneliness, isolation	0.4	0.5	2.4	-1.6	-0.8	0.3	-0.8	0.2	-0.2	-0.3	-0.1
Long-standing illness, disability or infirmity	0.9	1.4	4.2	0.9	-0.1	-0.4	-0.6	-0.2	-2.0	-1.9	1.5
Ever had bowel cancer screening	0.3	0.4	1.3	-1.1	0.3	0.4	0.2	0.1	-0.9	-0.6	0.5
Diabetes diagnosed by doctor	1.2	1.9	7.4	-0.8	0.0	0.9	-0.2	-1.1	-1.9	-2.7	1.2
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.6	1.5	0.1	1.0	0.3	0.5	0.0	-1.0	-1.1	1.2
Friendships satisfaction	0.7	0.9	2.3	-1.5	-0.8	0.7	-0.8	0.7	1.2	0.9	0.6
Qualifications: nursing, teaching	2.9	4.6	10.6	-1.3	-2.5	0.2	-2.9	2.3	2.0	0.5	3.3
Commuting to job workplace: Walk	1.0	1.1	3.1	1.7	-0.2	-1.4	0.4	0.1	0.5	0.4	-1.7
Eye problems/disorders: Cataract	0.6	0.7	2.4	0.5	-0.7	0.1	-1.0	0.9	0.4	-0.6	1.5
Mouth/teeth dental problems: Mouth ulcers	0.3	0.4	1.6	0.3	0.5	-1.3	0.2	0.7	-0.5	0.6	-0.3
Medication for cholesterol	1.1	1.7	4.5	0.5	1.4	0.0	1.5	0.1	0.7	2.1	-2.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.2	2.6	5.7	0.6	2.3	-0.7	2.4	1.2	1.3	1.8	-1.7
Back pain experienced in last month	1.1	1.6	2.8	-1.7	1.0	0.6	1.3	-1.6	-1.2	-0.2	-1.5
Mineral and other dietary supplements	1.0	1.3	3.5	1.0	0.5	-0.9	-0.3	1.7	-0.5	-1.3	1.9
Breast cancer (self-reported)	1.8	2.1	7.8	-0.5	-2.8	-0.6	-2.3	1.0	1.0	0.3	0.9
Asthma (self-reported)	0.9	1.9	4.3	1.0	1.8	0.4	1.7	-0.6	0.7	2.1	-1.4
Osteoporosis (self-reported)	0.2	0.3	0.5	0.7	0.5	-0.6	0.4	0.6	0.4	0.5	-0.3
Osteoarthritis (self-reported)	0.6	0.7	2.8	1.1	1.7	0.5	1.2	-0.1	-0.4	0.0	0.1
Medication: Aspirin	0.8	1.0	3.0	1.7	0.7	0.0	1.4	-1.0	-0.7	-0.2	-1.2
Medication: Gliclazide	0.6	0.6	1.7	-1.3	-0.3	1.2	-0.2	-0.4	0.7	-0.7	0.9
Illnesses of father: None of the above (group 1)	2.3	2.8	5.8	1.0	-2.0	0.8	-2.0	-1.0	-2.1	-2.4	1.2
Smoking status: Current	0.2	0.2	0.9	0.5	0.1	1.0	-0.0	-0.5	-0.5	-0.3	0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.5	4.5	-0.6	-1.8	-0.7	-2.1	1.0	0.2	0.4	1.5
Whole body water mass	0.4	2.1	6.9	-0.6	-0.4	2.5	-0.1	-2.6	-1.3	-1.1	0.6
Leg predicted mass (right)	0.6	3.0	8.6	-1.0	-0.2	2.7	-0.2	-2.9	-2.0	-1.5	1.1
Arm fat mass (left)	0.7	3.0	9.8	-0.1	0.5	1.1	0.1	-2.2	-3.1	-2.6	1.0
Number of self-reported non-cancer illnesses	0.9	1.6	7.5	1.4	0.8	-0.1	0.1	-0.8	-2.7	-1.3	0.7
Average weekly champagne plus white wine intake	2.8	3.9	6.3	-1.5	-2.2	2.5	-2.4	-1.6	-1.5	-1.4	2.2
Miserableness	1.3	2.3	5.0	-0.7	-1.3	1.8	-1.8	-0.7	-1.2	-1.6	2.2
Guilty feelings	0.3	0.4	1.6	-0.2	-1.3	-0.1	-0.8	-0.1	-0.1	-0.9	-0.3
Wears glasses or contact lenses	0.8	1.0	2.0	0.2	-0.9	1.4	-1.1	-0.7	-0.8	-1.0	1.3
Ever taken oral contraceptive pill	1.2	1.3	2.6	-1.6	0.9	1.3	1.1	-1.4	-0.1	0.3	-1.3
Hearing aid user	1.0	1.2	2.7	-0.0	-1.0	1.6	-0.8	-1.6	-0.5	-1.0	1.1
Mother’s age at death	0.8	1.0	2.8	0.9	-0.3	-1.7	-0.6	0.4	-1.6	-1.1	0.5
Financial situation satisfaction	0.2	0.2	0.8	0.4	-0.5	0.2	-0.5	-0.1	-0.4	0.1	0.9
Tinnitus: Yes, now most or all of the time	0.1	0.2	0.4	0.5	-0.6	0.0	-0.4	-0.5	-0.3	-0.4	-0.0
Commuting to job workplace: Public transport	0.6	0.8	3.1	0.2	-0.8	0.3	-0.4	0.8	1.8	0.8	0.9
Eye problems/disorders: Glaucoma	2.2	2.6	6.6	-1.4	-2.6	0.4	-2.5	0.6	0.6	-0.6	2.1
Medication: Blood pressure	0.3	0.6	1.7	-0.2	-0.4	0.4	-0.6	-0.7	-1.0	-1.3	1.1
Pain type(s) experienced in last month: Hip pain	0.7	0.9	2.9	0.9	-0.4	1.7	-0.3	-1.1	-0.2	-1.0	1.0
Supplements: Fish oil (including cod liver oil)	1.2	1.6	5.1	-2.2	-1.3	1.1	-0.4	-1.4	1.0	0.7	-0.9
High cholesterol (Self-reported)	0.7	1.3	2.9	0.8	-0.6	-1.7	-0.7	0.7	-1.5	-1.7	0.0
Medication: Bendroflumethiazide	0.5	0.8	2.1	0.2	1.1	-0.5	1.0	-1.4	-0.8	-0.3	-1.1
Medication: Paracetamol	0.3	0.5	0.9	1.0	0.6	0.4	0.2	-0.6	-0.9	-0.8	0.8
Medication: Lisinopril	0.5	0.6	2.4	-0.3	0.3	-1.5	-0.0	1.2	-0.8	-0.6	-0.1
Medication: Atorvastatin	0.3	0.4	1.1	0.5	-0.8	-1.1	-0.7	0.1	-0.3	-0.5	-0.1
Illnesses of father: High blood pressure	0.5	0.6	2.3	-0.5	-0.0	-1.5	-0.4	1.2	0.0	-0.5	0.7
Alcohol drinker status: Never	2.6	3.1	6.8	2.6	-2.0	1.4	-2.1	-0.4	-0.6	-1.4	2.3
Ever smoked	0.3	0.5	1.5	-0.5	0.3	1.2	0.6	-1.0	0.0	-0.0	-0.7
Basal metabolic rate	0.4	2.2	7.0	-0.6	-0.3	2.2	-0.1	-2.7	-1.7	-1.5	0.6
Leg fat percentage (left)	0.9	3.2	11.1	0.1	0.0	0.2	-0.3	-1.8	-3.3	-3.3	0.7
Arm fat-free mass (left)	0.3	1.8	6.3	-0.1	-0.5	2.0	-0.2	-2.5	-1.2	-1.3	0.4
Number of operations (self-reported)	1.9	2.8	10.4	-0.3	-1.2	3.2	-1.2	-1.9	-0.7	-0.9	2.1
Average weekly beer plus cider intake	0.5	0.7	2.8	0.4	0.0	0.4	0.0	-1.2	-1.7	-0.8	-0.4
Irritability	0.5	0.9	2.6	-1.6	-1.6	0.5	-1.2	0.3	0.6	0.4	-0.3
Risk taking	1.1	1.6	5.2	-0.2	1.3	0.2	1.8	-1.3	-0.2	0.8	-2.3
Ever had prostate specific antigen (PSA) test	0.3	0.3	1.6	-0.7	-0.0	1.3	0.3	-0.6	-0.1	0.0	-0.1
Fractured/broken bones in last 5 years	1.8	2.4	6.2	1.3	0.1	1.5	-0.5	-1.8	-2.5	-2.2	0.7
Age started oral contraceptive pill	0.1	0.1	0.4	-0.2	-0.6	-0.0	-0.2	0.4	0.4	0.2	0.0
Diastolic blood pressure, automated reading	0.4	1.2	3.5	-1.1	-0.8	-1.9	-0.3	0.7	0.7	0.9	-1.4
Ever depressed for a whole week	0.5	0.6	2.2	-0.4	-0.9	1.5	-0.6	-0.6	-0.3	-0.9	0.6
Unable to work because of sickness or disability	0.6	0.8	2.5	0.3	-0.4	0.7	-0.5	-0.7	-1.6	-1.4	0.5
Commuting to job workplace: Cycle	0.4	0.5	1.6	-0.3	1.3	-0.4	1.0	0.1	-0.2	0.8	-0.8
Myopia	0.3	0.5	1.0	-1.0	1.0	0.3	0.8	0.5	0.4	0.1	-1.0
Vascular/heart problems diagnosed by doctor	0.3	0.9	1.9	-0.5	-1.3	-0.3	-1.0	1.4	1.4	0.6	-0.2
Cholesterol lowering medication	0.2	0.4	1.0	1.0	-0.6	-0.7	-0.3	-0.1	-0.2	-0.9	0.3
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	1.5	-0.6	-0.9	0.3	-0.9	0.2	-0.3	-0.8	1.2
Pain experienced in last month	0.7	1.2	2.5	-1.0	-1.1	-0.1	-1.6	1.6	0.3	-0.4	1.4
Supplements: Calcium	0.5	0.6	1.2	-0.5	-0.8	-0.4	-0.1	0.2	1.1	1.1	-1.0
Basal cell carcinoma (self-reported)	0.9	1.0	3.2	-0.3	-0.4	-0.5	-0.9	1.3	1.4	0.5	1.8
Heart attack/myocardial infarction (self-reported)	0.5	0.7	3.1	-0.4	-0.2	1.4	0.2	-1.8	-0.3	-0.5	0.0
Deep venous thrombosis (DVT) (self-reported)	0.1	0.2	0.6	-0.0	0.1	0.6	0.1	-0.1	-0.8	-0.1	0.6
Heart disease (siblings)	0.6	0.8	3.8	1.9	0.3	0.6	0.1	-0.7	-0.5	-0.5	1.0
Alcohol drinker status: Previous	0.3	0.3	1.3	-0.4	-0.3	0.4	-0.3	0.4	-0.2	-0.9	1.2
Pack years of smoking	0.9	1.3	2.3	1.0	0.6	1.4	0.8	-1.3	-1.5	-1.5	-0.1
Impedance of whole body	0.9	4.4	11.4	2.3	1.4	-3.4	1.7	1.6	1.3	1.0	-2.9
Leg fat mass (left)	0.8	3.0	9.6	0.1	-0.1	0.4	-0.4	-1.9	-3.1	-3.1	1.0
Arm predicted mass (left)	0.3	1.7	6.1	-0.2	-0.6	2.0	-0.4	-2.5	-1.2	-1.2	0.6