Hub : Genes

EPHA4

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0720	0.0290	7.3e-03	0.012	-0.002	-0.002	0.001	0.001	1.0e-02	6.2e-01	7.8e-01	2.1e-01	2.0e-01
2	GTEx	Testis	0.4450	0.0830	7.7e-07	0.043	NA	0.122	NA	0.049	5.3e-03	NA	4.7e-06	NA	3.1e-03
3	GTEx	Thyroid	0.1000	0.0420	9.2e-03	0.015	NA	0.022	NA	0.007	2.3e-02	NA	7.4e-03	NA	8.5e-02
4	METSIM	Adipose	0.0401	0.0167	2.7e-03	0.010	0.023	0.010	0.022	0.007	1.1e-02	1.6e-04	9.8e-03	2.1e-04	3.0e-02
5	NTR	Blood	0.0635	0.0147	2.4e-11	0.057	0.040	0.051	0.049	0.053	1.0e-17	5.1e-13	4.9e-16	1.5e-15	1.3e-16
6	ROSMAP	Brain Pre-frontal Cortex	0.0443	0.0211	1.3e-02	0.029	0.005	-0.002	0.004	0.004	1.2e-04	6.5e-02	7.9e-01	8.6e-02	7.7e-02
7	YFS	Blood	0.0893	0.0172	0.0e+00	0.099	0.077	0.105	0.105	0.106	1.1e-30	4.6e-24	1.5e-32	1.8e-32	1.2e-32
8	TCGA	Testicular Germ Cell Tumors	0.2520	0.1110	8.6e-03	0.126	0.026	0.106	NA	0.072	3.4e-05	4.1e-02	1.4e-04	NA	1.5e-03

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	0.4	0.6	1.2	0.4	0.1	1.0	-1.1	-1.0	-0.5	-0.8	-0.7
Bipolar Disorder or Schizophrenia	0.9	2.3	7.1	1.3	-0.6	-0.5	-0.5	-2.5	-0.2	-2.7	-1.5
Depressed Affect (Nagel 2018)	0.6	1.2	4.9	1.0	-2.2	-1.2	0.5	-0.5	0.0	-0.9	0.8
Depression (Nagel 2018)	0.4	0.6	2.5	0.2	-1.6	-0.9	0.4	0.2	-0.3	-0.0	-1.1
Intelligence (Savage-Jansen 2018)	0.4	1.1	2.4	0.4	1.0	1.3	-1.4	-0.8	-0.9	-0.6	-1.5
Neuroticism (Nagel 2018)	1.0	2.4	7.5	0.6	-1.9	-0.2	-0.5	-2.5	-0.4	-2.7	-0.9
Schizophrenia (2018)	1.3	2.6	7.4	1.5	-1.1	-1.5	0.3	-2.5	0.2	-2.7	-1.3
Schizophrenia vs Biploar Disorder	1.1	1.5	2.9	1.3	-0.8	-1.7	1.7	-1.0	1.0	-1.3	-0.0
Worry (Nagel 2018)	1.2	2.5	7.0	1.0	-1.3	0.7	-0.1	-2.6	0.7	-2.6	-1.4
Alzheimer’s Disease (in mother)	1.0	1.1	5.1	-2.3	1.6	0.5	-0.6	-0.7	-0.3	-0.2	0.5
Alzheimer’s Disease (in father)	1.0	1.1	3.0	1.4	0.0	-0.9	-1.0	0.9	-1.7	0.6	-0.9
Alzheimer’s Disease (including proxy)	0.6	0.9	3.5	-0.9	1.2	-0.2	-0.8	-0.5	-1.9	-0.4	0.6
Crohns Disease (2017)	0.8	1.8	5.5	2.3	1.5	-1.7	-0.8	-1.4	0.5	-1.0	-0.1
Irritable Bowel Disease (IBD)	0.3	0.7	2.8	1.7	-0.4	-0.8	-0.4	-0.2	1.2	0.1	-0.4
Ulcerative Colitis (UC)	0.4	0.8	3.1	0.4	-1.8	0.3	0.2	0.7	1.3	1.0	-0.3
Major Depression (MDD)	1.0	1.2	3.8	1.9	-1.7	-0.3	0.0	-0.3	-0.4	-0.4	1.7
Reaction Time	1.8	3.4	8.4	1.3	-2.9	-0.6	1.8	2.9	-0.5	2.1	0.6
Verbal and Numeric Reasoning (VNR)	0.6	1.5	3.5	0.6	1.1	1.9	-0.9	-1.5	-0.2	-1.4	-1.4
Breast Cancer	0.4	1.0	3.5	-1.9	1.4	-0.4	1.0	-0.0	0.8	0.2	0.7
Ovarian Cancer	0.3	0.4	1.8	0.8	-0.2	1.3	-0.3	0.1	0.7	0.3	-0.5
Prostate Cancer	1.3	1.8	5.3	-1.2	2.3	-1.5	-1.1	-0.2	-0.8	0.1	-1.8
Age at First Birth	0.8	1.1	4.1	1.1	0.2	-0.4	-0.5	-0.9	1.0	-1.1	-2.0
Bipolar Disorder (2011)	1.4	1.3	3.3	0.7	-1.4	-1.1	-1.4	0.9	-0.6	0.9	1.8
Body Mass Index (BMI) (2010)	0.3	0.4	1.0	0.6	-0.4	-0.6	0.0	-0.6	0.6	-1.0	-0.6
Coronary Artery Disease (CAD)	1.1	1.3	4.5	-0.5	-0.8	0.6	2.1	1.4	1.0	1.2	0.5
Crohns Disease (2012)	0.7	1.1	3.9	1.3	0.0	-2.0	-0.7	-0.4	1.0	-0.2	-1.1
Mean Putamen Volume	0.2	0.2	1.3	-0.5	-0.0	-1.1	-0.3	0.1	0.1	0.1	0.3
Fasting Glucose	1.5	1.7	5.4	-0.3	2.3	1.5	-0.3	-0.9	-2.0	-0.7	0.9
HbA1C	0.5	0.5	1.7	0.1	-0.3	0.2	-1.3	-0.4	-1.2	-0.5	-0.7
HDL Cholesterol	1.4	2.3	6.5	-0.3	1.4	-0.3	-2.4	-1.0	-2.5	-0.6	1.8
LDL Cholesterol	0.5	0.8	1.9	1.0	-0.9	0.5	0.6	-1.2	0.6	-1.4	0.7
Lupus	1.1	1.6	4.3	1.1	0.8	0.7	-0.2	-2.1	-0.3	-1.9	1.5
Neuroticism (2016)	0.3	0.4	1.8	-0.6	-0.6	0.2	-0.3	-0.2	-1.3	-0.4	0.1
Primary Biliary Cirrhosis	0.2	0.3	1.3	0.2	-0.4	1.1	-0.1	0.1	-0.7	0.0	0.4
Rheumatoid Arthritis	1.1	1.5	4.1	0.9	-1.0	0.5	1.6	1.0	2.0	1.3	-1.1
Schizophrenia (2014)	1.0	2.2	4.5	1.9	-1.5	-1.4	0.6	-1.9	0.3	-2.1	-1.1
Triglycerides	0.3	0.5	2.2	-0.6	-0.3	-0.7	0.4	0.2	0.4	0.3	-1.5
Type 2 Diabetes (T2D) (2012)	1.1	1.3	3.2	-0.3	-1.8	0.9	1.2	1.4	0.4	0.9	-1.3
Ulcerative Colitis	1.1	1.6	4.7	0.3	-1.8	0.6	0.7	1.7	0.9	2.2	-0.3
Blood Eosinophil Count	0.1	0.6	2.5	0.6	1.6	-0.2	0.2	-0.5	1.1	-0.4	0.0
Blood Platelet Count	0.3	3.4	13.0	1.2	1.6	-0.4	-3.6	0.7	-2.2	1.5	1.4
Blood Red Count	0.2	2.1	8.0	0.1	-2.8	-0.5	0.1	0.2	2.8	0.2	-0.7
Blood White Count	0.2	1.2	3.9	2.0	0.3	-0.6	-0.1	0.7	1.8	1.2	-0.0
Heel T-Score	0.4	2.8	10.0	-0.1	-0.7	-1.4	0.7	-2.7	0.5	-3.2	-1.6
BMI	0.3	1.7	4.7	0.4	-1.6	-0.6	-1.1	-1.2	2.2	-1.1	-1.2
Height	0.2	4.0	9.0	-1.7	-0.6	2.4	2.6	-1.6	0.7	-1.9	-3.0
Waist Hip Ratio (WHR)	0.6	2.5	4.7	-0.8	-0.4	-2.1	2.2	2.0	0.1	1.4	2.1
Systolic Blood Pressure	0.2	1.1	4.0	-1.7	-0.3	2.0	0.9	-0.6	0.5	-0.3	0.2
Smoking Status	0.4	0.9	2.7	0.3	-0.6	-0.4	1.7	-0.9	0.4	-1.2	-1.0
Allergy or Eczema	0.4	1.0	4.9	1.4	0.6	-2.2	-0.4	0.4	-0.5	0.4	0.2
Cardiovascular Disease	0.8	2.8	9.5	-0.2	0.7	0.5	-1.7	-3.1	-0.7	-2.7	-1.2
Hypothyroidism (self reported)	0.5	1.2	5.2	0.5	-0.8	1.0	2.3	1.1	0.1	1.1	0.5
Respiratory disease	1.0	2.3	6.2	2.5	-1.6	-2.3	-1.1	0.4	-0.1	0.3	-1.6
Type 2 Diabetes (T2D) (2018)	0.7	1.3	5.3	-0.7	1.4	2.3	-0.3	0.3	-0.0	0.5	-1.4
Lung FEV1/FVC ratio	0.2	0.9	3.4	-0.5	-0.2	0.5	-0.9	1.2	-0.1	1.1	-1.9
Lung FVC	0.2	1.2	2.6	1.5	-0.8	-0.8	-1.1	-0.9	-1.6	-1.3	0.4
Neuroticism	0.8	2.0	5.9	1.1	-1.5	-0.8	-0.5	-2.3	0.1	-2.4	-0.4
Chronotype (morning person)	0.7	1.7	5.1	-0.8	1.0	-0.6	-0.8	-2.2	-0.8	-2.1	0.9
Hair Pigment	6.5	186.1	441.0	0.1	-14.0	19.4	21.0	11.7	15.0	9.1	5.7
Tanning	0.2	2.1	6.1	0.1	1.8	-2.5	-1.4	0.2	-2.5	0.2	0.2
Hand grip strength (left)	0.4	0.9	2.1	0.2	0.3	-0.5	-1.2	-1.3	-1.0	-1.4	-0.8
Number of treatments/medications taken	0.4	0.7	2.5	-0.0	-1.1	-0.2	-1.3	-0.2	-1.6	-0.1	0.0
Average weekly spirits intake	1.4	1.8	4.1	0.1	1.9	-0.3	-2.0	-0.2	-1.8	-0.2	-1.8
Sensitivity / hurt feelings	1.7	2.9	6.0	-0.7	1.6	-0.8	-2.0	-2.4	-2.2	-2.1	0.2
Frequency of depressed mood in last 2 weeks	0.7	1.0	2.5	-1.5	-0.8	-1.6	0.3	0.3	-1.1	-0.1	1.0
Hearing difficulty/problems: Yes	0.4	0.6	1.8	-0.4	0.1	0.4	0.1	1.1	-0.1	1.4	1.3
Relative age of first facial hair	1.6	3.2	7.1	-1.5	0.2	1.3	2.0	-1.5	2.5	-1.5	-2.7
Other serious medical condition/disability diagnosed by doctor	1.7	2.2	6.1	1.1	-1.1	-0.1	1.7	2.5	1.1	2.2	-0.1
Ever used hormone-replacement therapy (HRT)	1.1	1.5	2.6	1.4	1.6	-0.5	-1.4	-1.0	-1.3	-0.6	-1.4
Ever had hysterectomy (womb removed)	0.6	0.7	1.6	1.2	0.5	-1.3	-0.5	-0.9	-0.9	-0.7	0.3
Systolic blood pressure, automated reading	0.1	0.3	1.6	-1.3	-0.5	0.0	0.4	0.0	-0.1	0.3	-0.8
Eye problems/disorders: Diabetes related eye disease	0.5	0.5	1.5	0.5	0.3	-0.6	1.2	0.5	1.2	0.3	-0.4
Angina	0.4	0.5	1.2	-0.9	1.1	-0.3	0.8	0.3	1.1	0.5	0.4
Medication for hormone replacement therapy	2.8	3.2	6.0	1.6	0.3	-1.3	-2.1	-2.3	-2.4	-2.2	-0.6
Vitamin and mineral supplements	1.6	2.1	5.4	-0.5	-1.5	-0.1	1.4	1.9	2.3	1.8	0.3
Supplements: Zinc	0.5	0.5	1.4	0.9	-0.5	1.2	1.2	0.2	-0.3	0.2	-0.3
Medication: Co-codamol	1.3	1.5	6.7	1.4	-0.9	-2.6	1.5	-0.4	0.0	-0.4	0.1
Medication: Metformin	0.5	0.7	2.5	0.5	1.6	0.7	-1.0	-0.4	-0.5	-0.1	-0.7
Diabetes (father)	1.9	2.3	7.0	-0.9	-1.4	0.2	2.6	1.2	2.0	1.4	1.0
Diabetes (mother)	0.2	0.2	0.5	0.7	-0.2	-0.2	0.7	0.5	0.5	0.2	0.4
Severe depression (siblings)	1.1	1.3	4.5	2.1	-0.7	-1.1	-0.3	-0.1	-1.0	-0.3	1.7
Pack years adult smoking proportion	0.2	0.3	0.5	-0.3	-0.7	0.4	-0.5	0.7	-0.1	0.7	-0.4
Impedance of leg (right)	0.2	0.8	4.5	0.3	2.1	0.6	-0.1	-0.7	-0.5	-0.4	-0.9
Leg fat-free mass (left)	0.3	1.6	5.6	-0.6	-2.4	0.6	1.1	-0.4	1.7	-0.8	-1.3
Trunk fat percentage	0.4	1.4	3.2	-0.1	-1.6	-0.2	-0.1	-1.5	0.3	-1.7	-1.8
Hand grip strength (right)	0.4	1.1	4.4	0.5	0.9	-0.2	-2.1	-1.1	-0.4	-1.2	-0.7
Townsend deprivation index at recruitment	0.9	1.3	2.3	0.7	-1.3	-0.9	1.3	1.5	1.1	1.4	0.3
Current tobacco smoking	0.5	0.8	2.6	0.3	-1.6	-1.2	0.7	1.0	0.9	0.5	0.0
Average weekly fortified wine intake	0.2	0.3	0.9	0.2	-1.0	-0.3	-0.7	-0.3	-0.4	-0.3	0.7
Maternal smoking around birth	1.0	1.5	7.1	0.8	1.0	-1.2	2.7	-0.0	0.5	-0.2	1.2
Fed-up feelings	0.5	0.9	1.9	1.4	-1.1	-0.3	0.0	-0.7	-0.5	-1.1	1.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	0.9	4.3	-0.3	0.5	-2.1	-0.5	-0.2	-1.4	-0.3	0.1
Relative age voice broke	1.4	2.1	4.7	-1.4	1.0	1.3	2.2	-1.3	1.6	-1.1	-1.4
Taking other prescription medications	0.5	0.8	2.5	0.9	-0.8	-0.1	-0.4	0.6	-1.6	0.9	1.0
Age when periods started (menarche)	0.5	1.2	4.2	-1.4	-0.4	-0.4	2.1	-0.2	1.7	-0.2	0.4
Bilateral oophorectomy (both ovaries removed)	1.1	1.2	3.7	1.2	1.0	-0.8	-1.9	-1.3	-0.8	-0.9	-0.3
Heel bone mineral density (BMD) T-score, automated (left)	1.4	3.1	11.7	0.6	-1.6	-1.1	1.2	-2.6	0.3	-3.4	0.7
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.3	-0.5	-0.6	-0.0	-0.5	0.3	-0.4	0.0	-0.1
Qualifications: CSEs or equivalent	0.5	0.7	2.1	0.3	0.3	-1.4	-1.4	-0.5	-0.5	-0.3	0.8
Serious illness, injury or assault to yourself	0.3	0.3	0.9	0.7	-0.5	0.9	0.9	0.1	0.4	-0.2	-0.1
High blood pressure	0.5	1.4	4.0	-2.0	0.2	0.7	-0.4	-2.0	-0.6	-1.4	-0.7
Hayfever, allergic rhinitis or eczema	0.8	1.7	5.0	1.0	0.3	-2.2	-0.3	1.7	-1.1	1.6	0.9
Multivitamins +/- minerals	1.5	1.9	5.2	0.6	0.4	-0.1	-1.6	-2.3	-1.4	-2.2	-0.1
Stomach or abdominal pain in last month	0.4	0.5	1.2	0.1	-0.7	0.9	-1.0	0.4	-0.2	0.5	1.1
Supplements: Glucosamine	0.5	0.7	3.0	-0.2	-1.7	-0.6	0.6	-0.0	-0.7	-0.4	-1.0
Diverticular disease/diverticulitis (self-reported)	0.5	0.6	2.2	1.1	0.1	0.6	0.4	-0.3	0.1	-0.6	1.5
Medication: Atenolol	0.4	0.5	0.9	-0.3	-0.8	-0.9	0.1	0.7	0.8	0.9	-0.2
Medication: Levothyroxine sodium	0.5	0.9	1.6	1.1	-0.9	1.0	1.2	1.0	0.2	1.1	0.0
Sitting height	0.6	4.2	11.8	-2.0	0.0	3.4	2.5	-1.2	0.7	-1.6	-2.7
Chronic bronchitis/emphysema (father)	1.1	1.3	2.4	1.3	-1.6	-1.4	-1.1	-0.7	-1.2	-0.7	0.8
High blood pressure (mother)	0.6	0.9	3.6	-0.7	0.1	1.9	-1.2	-0.6	0.0	-0.6	-1.0
Body mass index (BMI)	0.3	1.3	4.8	0.6	-2.2	-0.8	-0.6	-0.6	1.3	-0.9	-1.2
Impedance of leg (left)	0.3	1.4	5.8	0.3	2.4	0.6	-0.4	-1.2	-1.2	-1.1	-0.6
Leg predicted mass (left)	0.3	1.6	5.5	-0.6	-2.3	0.6	1.1	-0.4	1.7	-0.8	-1.3
Trunk fat mass	0.4	1.6	4.2	-0.3	-1.8	0.2	0.0	-1.5	0.6	-1.7	-2.0
Waist circumference	0.2	0.7	2.3	0.1	-1.1	-0.6	0.1	-0.3	1.5	-0.6	-1.1
Number of incorrect matches in round	0.6	1.0	2.9	-1.7	1.4	-0.8	0.5	0.5	0.1	0.5	1.3
Past tobacco smoking	0.9	1.7	7.5	0.2	-0.2	-0.6	-1.0	1.2	-0.7	1.7	2.7
Alcohol usually taken with meals	0.2	0.3	0.7	0.7	0.9	0.9	-0.1	0.3	-0.6	0.1	-0.2
Nervous feelings	1.0	1.8	4.3	0.2	-1.0	0.5	0.6	-1.7	2.1	-1.8	-1.4
Frequency of tenseness / restlessness in last 2 weeks	0.7	1.1	3.7	-0.1	-0.4	-1.9	-0.7	-0.9	-1.5	-0.9	-0.1
Hearing difficulty/problems with background noise	0.5	0.8	1.8	0.7	-1.3	-1.4	0.1	1.1	0.0	1.0	0.5
Hair/balding pattern: Pattern 2	2.8	3.5	8.9	2.5	-0.6	-1.6	-0.0	-2.7	-0.8	-3.0	-1.6
Had menopause	0.8	1.0	5.8	1.2	0.0	-0.2	0.2	-0.1	0.6	0.2	-2.4
Had other major operations	0.7	0.9	2.1	-0.3	-0.1	-1.1	1.4	-1.1	-0.3	-1.4	0.7
Forced vital capacity (FVC)	0.1	0.2	0.9	0.4	0.1	0.2	-0.1	-0.8	0.1	-0.9	-0.1
Heel bone mineral density (BMD) T-score, automated (right)	1.5	3.4	12.0	1.4	-0.9	-1.7	0.0	-3.0	0.3	-3.5	0.6
Ever unenthusiastic/disinterested for a whole week	1.3	1.6	4.4	-0.5	-1.0	-1.3	0.8	-1.6	-0.3	-2.1	1.4
Qualifications: None of the above	1.6	3.4	9.5	-0.1	-0.1	-1.3	2.2	3.1	1.5	2.9	-0.5
Financial difficulties in last 2 years	0.1	0.1	0.4	-0.4	-0.6	0.1	0.3	0.3	-0.2	-0.1	-0.0
Mouth/teeth dental problems	1.2	1.8	4.6	-0.5	1.6	-1.2	-2.1	1.5	-0.6	1.6	-0.1
Heart attack	0.6	0.8	3.0	1.7	-0.2	0.1	-0.9	-0.7	-1.3	-0.3	0.6
Allergy	0.6	1.3	2.7	-1.6	0.1	1.4	0.7	-1.3	1.5	-1.3	-0.5
Pain all over the body in last month	1.2	1.2	7.4	-0.1	-0.5	0.3	1.1	0.5	2.7	0.5	-0.7
Diabetes (self-reported)	0.6	0.9	2.8	-1.5	1.7	1.1	-0.3	0.4	0.6	0.7	-0.3
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	1.6	-0.7	-1.3	0.5	-0.1	-0.7	-0.1	-0.6	-0.7
Medication: Ramipril	0.4	0.5	2.6	0.5	-0.1	0.3	0.5	0.5	-0.2	0.6	1.6
Medication: Simvastatin	0.4	0.5	1.2	-1.1	0.3	-0.2	-1.1	-0.4	-0.8	-0.1	1.0
Fluid intelligence score	0.5	1.0	2.7	0.0	0.8	1.4	-1.0	-1.6	0.3	-1.2	0.2
Illnesses of siblings	0.4	0.6	2.0	-1.3	0.5	1.4	0.2	0.0	-0.1	-0.2	-0.8
Neuroticism score	0.8	1.7	5.9	0.7	-0.3	-1.0	-0.9	-2.2	-0.7	-2.4	-0.1
Weight	0.3	1.6	4.0	-0.4	-1.9	0.4	0.4	-1.0	1.5	-1.3	-2.0
Impedance of arm (right)	0.2	0.7	2.1	-1.0	1.4	-0.6	0.9	-0.8	-0.2	-0.9	-0.5
Arm fat percentage (right)	0.3	1.3	2.7	-0.0	-1.6	-1.0	-0.4	-1.1	1.1	-1.3	-1.5
Trunk fat-free mass	0.3	1.5	3.8	-0.7	-1.5	1.6	1.4	0.2	2.0	-0.2	-1.0
Hip circumference	0.4	1.6	3.7	0.3	-1.2	0.9	-0.5	-1.5	1.2	-1.7	-1.9
Time employed in main current job	0.4	0.5	1.3	-0.5	-0.3	-0.2	-1.0	-1.2	-0.1	-1.1	0.3
Alcohol intake versus 10 years previously	0.6	0.9	1.9	-1.2	0.0	0.7	1.0	-1.0	1.4	-1.1	-0.1
Father’s age at death	2.6	3.4	13.5	0.1	-1.7	2.4	1.6	0.4	3.7	0.4	-1.4
Worrier / anxious feelings	1.3	2.5	7.7	0.4	0.5	1.4	-0.4	-2.8	0.0	-2.6	-1.7
Frequency of tiredness / lethargy in last 2 weeks	1.0	1.6	3.3	1.2	-1.6	-1.8	1.7	0.8	1.0	0.7	0.6
Falls in the last year	0.3	0.5	1.4	-0.0	0.3	0.5	1.2	-0.7	0.6	-0.6	0.8
Hair/balding pattern: Pattern 3	0.3	0.5	1.9	-0.4	-0.6	1.4	-0.5	0.0	1.1	0.0	0.1
Number of live births	0.4	0.5	1.2	-0.2	-0.7	0.5	-0.2	0.8	1.0	1.1	-0.6
Forced expiratory volume in 1-second (FEV1)	0.1	0.2	0.5	0.3	-0.5	-0.3	-0.1	-0.5	0.1	-0.7	-0.5
Pulse rate	0.6	0.9	5.4	0.8	-2.3	0.2	-0.9	0.5	0.4	0.4	-0.4
Happiness	0.8	0.9	2.6	-0.1	0.4	0.5	-0.1	1.4	-1.6	1.0	1.2
Noisy workplace	1.4	1.8	3.6	-1.7	-0.4	-1.3	1.9	1.9	0.0	1.3	0.9
Qualifications: A levels/AS levels or equivalent	0.6	1.3	5.4	-0.0	0.7	0.4	0.2	-1.8	-1.0	-2.3	-0.3
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.6	1.5	1.2	0.5	-1.0	0.2	-1.0	-0.4	-0.9	-0.2
Mouth/teeth dental problems: Dentures	0.7	1.2	7.7	-0.4	-1.0	0.3	2.8	-0.5	0.4	-0.5	0.2
Asthma	0.9	1.7	7.6	2.8	0.0	-0.5	-1.2	1.3	-0.2	1.5	-0.6
Medication: Ibuprofen (e.g. Nurofen)	0.8	1.0	3.6	-1.9	-1.8	0.4	-0.6	-0.1	0.1	-0.2	0.9
Medication: Cholesterol lowering	0.6	1.0	2.8	-0.9	0.2	1.1	-1.7	-0.8	-1.3	-0.7	0.5
Depression (self-reported)	1.6	1.9	5.5	0.1	-1.6	-1.2	0.0	-1.4	-2.4	-1.8	-0.7
Medication: Lansoprazole	0.7	0.8	1.6	1.3	1.1	0.6	-1.2	0.7	-0.1	1.1	0.6
Prospective memory result	0.4	0.5	2.9	-1.2	0.1	-1.7	0.2	-0.1	-0.2	-0.1	0.2
Lung cancer (father)	0.5	0.6	1.7	-0.4	1.3	1.0	-0.6	-0.0	-1.1	0.0	-0.4
Illnesses of mother	0.6	0.7	1.9	-0.6	-1.2	-1.4	0.9	0.7	-0.0	0.3	-0.6
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.3	1.0	0.1	-0.8	-0.3	-0.3	-0.3	-0.3	-0.8	-1.0
Pulse wave Arterial Stiffness index	0.7	0.8	2.2	0.4	1.5	-0.2	-1.2	-0.1	-1.2	-0.2	-0.9
Impedance of arm (left)	0.1	0.6	1.6	-1.0	1.3	-0.7	0.9	-0.5	-0.4	-0.5	0.0
Arm fat mass (right)	0.3	1.3	2.9	-0.2	-1.6	-0.2	-0.1	-1.2	1.3	-1.4	-1.7
Trunk predicted mass	0.3	1.6	3.8	-0.7	-1.6	1.7	1.5	0.1	2.0	-0.2	-0.9
Standing height	0.3	2.9	6.9	-2.3	0.3	2.6	2.3	-0.9	0.8	-1.2	-1.9
Length of working week for main job	1.1	1.2	2.4	-1.1	0.4	0.3	-1.4	-1.5	-0.9	-1.1	1.2
Exposure to tobacco smoke at home	0.7	0.8	1.7	1.1	-1.3	-0.4	-0.4	0.9	0.2	1.2	1.1
Breastfed as a baby	0.5	0.6	1.4	1.0	0.5	0.8	-0.1	-1.2	-0.2	-1.1	-0.1
Tense / ‘highly strung’	1.8	3.0	6.3	0.3	0.6	-1.1	-2.3	-2.5	-2.1	-2.5	-0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.9	1.3	2.7	0.3	-1.4	-1.0	-0.6	-1.4	-1.6	-1.6	-0.4
Hair/balding pattern: Pattern 4	2.4	5.8	19.4	-0.5	0.2	-0.1	2.1	4.3	0.5	4.4	1.9
Birth weight of first child	0.5	1.0	4.8	-0.5	-0.2	2.2	-0.7	0.4	-1.1	0.1	-1.0
Peak expiratory flow (PEF)	0.2	0.4	1.2	1.1	-0.1	0.3	-0.8	-0.6	-0.1	-1.1	-0.1
Pulse wave reflection index	0.5	0.6	3.0	-0.5	0.5	-0.7	0.1	-0.4	-1.7	-1.0	0.1
Ever highly irritable/argumentative for 2 days	0.8	0.9	2.4	-0.8	-0.8	-0.2	0.3	-1.4	-1.2	-1.5	-0.5
Loud music exposure frequency	0.2	0.2	0.6	-0.6	0.2	-0.3	-0.7	-0.1	-0.8	-0.3	-0.5
Qualifications: O levels/GCSEs or equivalent	1.2	1.8	5.3	0.5	0.3	2.2	-0.3	-1.9	0.5	-2.3	0.8
Mouth/teeth dental problems: Bleeding gums	0.6	0.8	2.0	0.7	-1.2	0.8	0.5	-1.4	-0.3	-1.1	-0.0
Blood clot in the leg (DVT)	2.4	3.1	7.7	-0.3	2.0	-0.8	-2.8	-2.0	-2.4	-1.6	-0.3
Medication: Paracetamol	1.2	1.9	4.4	-1.3	-1.3	-1.6	-0.2	-1.9	-0.1	-2.1	1.2
Headache pain in last month	1.0	1.7	9.9	-1.3	-3.1	-0.9	0.6	0.2	0.8	0.0	0.6
Medication for cholesterol, blood pressure or diabetes	0.9	1.5	2.7	1.2	-1.0	-0.9	1.5	1.6	1.3	1.2	0.5
Glaucoma (self-reported)	0.6	0.7	3.8	0.1	-0.6	1.1	1.9	0.3	0.4	0.2	-0.1
Gout (self-reported)	0.7	1.0	3.3	0.9	0.7	1.3	-1.0	0.3	-1.8	0.4	0.7
Hypothyroidism/myxoedema (self-reported)	0.4	0.8	2.0	0.6	-0.1	1.4	1.1	0.8	-0.4	0.9	0.8
Medication: Amlodipine	0.2	0.3	0.8	-0.5	-0.3	0.2	-0.9	-0.6	-0.3	-0.2	-0.9
Medication: Ventolin 100micrograms inhaler	1.6	2.1	5.6	2.0	-0.6	0.3	-1.8	-0.0	-1.9	-0.1	-2.4
Birth weight	0.4	0.9	2.9	-1.7	-0.7	0.6	-0.4	-0.1	-1.0	-0.3	-1.5
Chronic bronchitis/emphysema (mother)	0.5	0.6	1.5	0.7	0.1	0.5	0.5	1.2	0.5	1.1	-0.8
High blood pressure (siblings)	0.5	0.8	3.6	1.9	-1.1	-1.1	-0.1	-0.2	0.2	0.1	0.0
Forced vital capacity (FVC), Best measure	0.1	0.2	0.8	0.2	-0.5	-0.1	0.1	-0.5	-0.0	-0.9	-0.6
Body fat percentage	0.4	1.5	3.1	0.3	-1.6	-0.8	-0.7	-1.6	0.4	-1.6	-1.8
Leg fat percentage (right)	0.4	1.5	2.6	0.9	-1.5	-0.8	-1.3	-1.5	0.4	-1.4	-1.6
Arm fat-free mass (right)	0.3	1.5	3.9	-0.2	-1.7	2.0	0.8	-0.4	1.3	-0.6	-1.6
Exposure to tobacco smoke outside home	0.4	0.5	1.9	1.4	-0.6	-1.1	-0.2	0.0	-0.6	0.1	-0.3
Comparative body size at age 10	0.3	0.9	5.7	1.1	-2.4	0.1	-0.6	0.1	-0.0	-0.1	-0.3
Number of full brothers	1.2	1.5	3.2	0.0	0.5	0.6	-1.6	-1.8	-1.3	-1.5	-1.3
Worry too long after embarrassment	0.6	1.0	5.9	-0.0	-2.4	0.0	0.9	-0.1	0.7	-0.5	-0.6
Seen a psychiatrist for nerves, anxiety, tension or depression	1.1	1.5	4.1	-1.0	-1.6	-1.3	-0.7	-0.7	-2.0	-1.0	-0.8
Wheeze or whistling in the chest in last year	1.8	3.2	5.1	2.0	-1.5	-1.9	1.6	2.2	1.6	2.1	0.7
Number of children fathered	1.4	1.6	7.2	-0.9	0.8	1.2	-1.5	0.6	-2.7	0.3	0.4
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.6	2.2	-0.1	-0.9	1.1	0.6	-0.3	-1.5	-0.4	-0.3
Age at first live birth	0.7	1.3	3.8	-0.1	1.5	1.6	-1.9	-0.8	-0.1	-0.8	-0.6
Pulse wave peak to peak time	0.5	0.6	1.5	-0.7	-1.2	0.6	1.1	0.0	1.0	0.1	0.6
Health satisfaction	0.9	1.2	7.8	2.8	-0.3	-0.5	0.2	-0.5	-0.2	-0.9	-0.1
Shortness of breath walking on level ground	0.3	0.3	1.3	1.2	0.0	0.6	-0.0	-0.2	-0.8	-0.1	0.4
Qualifications: College or University degree	0.4	1.2	2.7	0.3	0.4	1.0	-1.6	-1.5	-0.8	-1.3	-0.8
Eye problems/disorders: None of the above	0.8	0.9	4.6	0.7	-0.0	-1.2	-2.1	0.2	-0.9	0.1	-0.1
Mouth/teeth dental problems: Loose teeth	1.5	1.8	4.2	-0.6	-0.5	1.8	1.2	-1.2	-1.1	-1.3	2.0
Emphysema/chronic bronchitis	0.4	0.5	1.5	-0.5	-1.2	-0.2	-0.1	-0.4	0.7	-0.8	-0.8
Medication for pain relief, constipation, heartburn	0.8	1.3	4.0	1.4	1.7	0.7	0.7	-0.4	0.6	-0.3	-2.0
Neck or shoulder pain in last month	1.1	1.6	7.6	-0.3	-0.2	-0.8	-2.8	-0.7	-1.7	-1.0	-0.4
Medication: Blood pressure	0.6	1.0	5.0	-2.2	0.8	0.0	-0.2	-1.2	0.1	-0.6	-1.0
Angina (self-reported)	0.4	0.5	1.2	-1.1	1.0	-0.4	0.8	0.2	1.1	0.4	0.2
Migraine (self-reported)	0.8	0.9	3.2	0.5	-0.5	0.1	0.9	1.2	1.8	1.0	-0.6
Medication: Ibuprofen	1.0	1.2	5.4	-2.3	-1.0	0.0	-0.5	0.7	-0.1	0.5	1.4
Medication: Allopurinol	1.0	1.4	8.1	2.9	-0.5	1.3	-0.6	-0.3	-0.7	-0.2	-0.3
Medication: Omeprazole	0.5	0.5	2.6	0.3	0.9	-1.6	-0.6	-0.0	0.5	0.2	0.4
Medication: Seretide 50 evohaler	0.9	1.0	3.5	1.1	0.6	-0.6	-1.6	0.4	-1.9	0.1	-0.3
Mean time to correctly identify matches	1.7	3.3	8.5	0.7	-2.8	0.4	2.0	2.9	-0.7	2.3	-0.4
Heart disease (mother)	1.3	1.5	3.4	1.9	0.9	0.6	-1.9	-1.4	-0.7	-1.1	-0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.9	1.0	2.1	-0.7	1.4	0.7	-1.2	-0.1	-1.4	0.1	1.3
Whole body fat mass	0.4	1.5	3.2	0.1	-1.8	0.1	-0.2	-1.4	0.9	-1.6	-1.8
Leg fat mass (right)	0.4	1.7	4.1	0.5	-1.7	-0.0	-0.7	-1.6	1.0	-1.6	-2.0
Arm predicted mass (right)	0.3	1.5	3.8	-0.3	-1.9	1.9	0.8	-0.2	1.5	-0.3	-1.3
Pulse rate, automated reading	0.4	1.4	6.9	0.2	-2.6	1.2	-0.8	-0.2	-0.3	-0.5	-1.3
Alcohol intake frequency.	0.8	1.8	4.7	0.1	-1.1	-1.4	0.8	1.4	1.2	1.5	2.2
Comparative height size at age 10	0.1	0.7	1.9	-0.5	0.8	1.4	1.3	0.1	-0.2	-0.2	-1.1
Number of full sisters	1.7	2.1	5.4	-0.7	1.5	0.6	-0.7	-2.3	-1.6	-2.3	-0.1
Suffer from ‘nerves’	0.9	1.5	4.4	0.1	-1.4	-0.7	-0.5	-2.1	-0.0	-2.0	0.7
Overall health rating	0.9	1.9	5.8	1.0	-1.7	-1.3	1.6	0.2	1.1	-0.1	2.4
Chest pain or discomfort	1.0	1.4	3.7	1.1	1.1	-1.5	1.2	-0.0	1.9	0.0	-1.2
Had major operations	0.4	0.4	0.7	-0.8	-0.7	0.4	0.6	-0.6	-0.6	-0.7	0.9
Age at last live birth	0.6	0.9	2.2	0.3	1.4	1.5	-1.2	-0.6	0.6	-0.3	0.7
Family relationship satisfaction	0.2	0.2	1.0	0.4	-0.4	0.3	-0.1	-0.0	-0.7	-0.2	1.0
Leg pain on walking	0.9	1.2	3.5	0.4	-1.1	-1.9	0.2	-1.4	-0.6	-1.4	-0.2
Qualifications: NVQ or HND or HNC or equivalent	0.8	0.9	2.9	-0.5	1.7	-0.5	-1.3	-0.5	-1.2	-0.3	0.5
Commuting to job workplace: Car/motor vehicle	1.7	1.9	4.2	2.0	-0.1	1.6	-1.2	-1.6	-0.4	-1.7	1.1
Illness, injury, bereavement, stress in last 2 years	0.6	0.7	2.4	-0.8	-0.1	0.6	-1.5	0.8	-0.6	1.1	-0.3
Medication: Aspirin	0.7	1.0	2.3	1.5	-1.1	1.2	0.0	1.2	0.4	1.2	0.1
Supplements: Vitamin C	1.4	1.7	3.4	-1.4	0.9	1.0	0.4	-1.7	-1.7	-1.9	-0.1
Knee pain experienced in last month	0.3	0.4	0.9	0.0	-0.8	-0.7	-0.6	-0.7	-0.9	-0.6	0.2
Hypertension (Self-reported)	0.5	1.4	3.9	-1.8	0.2	0.6	-0.3	-2.0	-0.8	-1.4	-1.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.3	1.6	6.1	0.3	-0.0	2.5	-1.1	0.9	1.5	1.4	0.4
Illnesses of father: Heart disease	0.5	0.7	1.5	0.7	-0.2	-0.8	0.8	0.9	0.5	1.2	-1.2
Illnesses of siblings: Diabetes	0.2	0.3	0.9	0.3	0.2	0.1	-1.0	0.6	-0.4	0.7	0.2
Smoking status: Previous	0.9	1.4	5.0	-0.6	0.3	1.2	1.7	-0.4	0.8	-0.6	-2.2
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.6	3.8	-2.0	-0.3	0.2	0.5	-0.0	-0.4	-0.4	-0.1
Whole body fat-free mass	0.3	1.6	3.6	-0.7	-1.9	1.4	1.3	-0.2	1.8	-0.5	-1.1
Leg fat-free mass (right)	0.3	1.4	5.3	-0.8	-2.3	0.5	1.1	-0.4	1.4	-0.9	-0.9
Arm fat percentage (left)	0.3	1.2	3.7	0.1	-1.9	-1.0	-0.5	-1.0	1.1	-1.1	-1.4
Average weekly red wine intake	0.8	1.1	4.1	0.6	0.2	0.1	-2.0	-0.4	-1.8	-0.8	0.5
Handedness (chirality/laterality): Left-handed	1.0	1.2	5.1	-0.4	-0.8	-2.2	0.7	-0.4	1.8	-0.3	-0.1
Mood swings	0.4	0.8	1.7	1.3	0.3	-1.1	-0.8	-0.4	-1.0	-0.8	1.0
Loneliness, isolation	0.5	0.7	3.1	0.6	-0.5	0.6	-0.5	-0.6	-1.8	-0.9	0.6
Long-standing illness, disability or infirmity	0.3	0.4	1.2	0.6	-0.1	-0.6	-0.4	0.9	0.5	1.1	0.6
Ever had bowel cancer screening	1.4	1.6	6.8	0.4	0.2	-1.6	-2.6	-0.7	-1.6	-0.4	0.2
Diabetes diagnosed by doctor	1.0	1.6	4.4	-1.7	1.7	2.1	-0.5	0.8	0.2	1.0	-0.9
Ever had stillbirth, spontaneous miscarriage or termination	1.7	1.8	8.2	-0.7	-0.5	2.9	0.6	0.2	2.3	0.3	-0.3
Friendships satisfaction	0.1	0.1	0.6	-0.1	-0.0	0.2	0.7	-0.1	0.2	-0.7	0.0
Qualifications: nursing, teaching	0.8	1.3	4.8	0.6	-0.8	0.8	-1.1	-1.0	-2.2	-1.1	-0.7
Commuting to job workplace: Walk	1.2	1.2	7.7	-2.8	0.5	-0.4	0.1	-0.0	0.2	0.0	-1.3
Eye problems/disorders: Cataract	0.8	0.9	2.1	0.2	-1.3	-0.6	0.9	-1.2	0.5	-1.5	0.8
Mouth/teeth dental problems: Mouth ulcers	0.7	1.1	3.9	1.8	-0.7	0.7	-0.0	-0.2	0.5	-0.7	-2.0
Medication for cholesterol	0.6	0.9	2.0	-0.5	-0.7	1.4	1.3	0.8	1.4	0.2	-0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.3	1.5	3.0	-0.5	0.5	-1.7	-0.8	-1.4	-1.7	-1.6	0.9
Back pain experienced in last month	0.4	0.6	1.2	1.1	0.5	-0.7	0.7	1.0	-1.0	0.6	0.3
Mineral and other dietary supplements	0.7	1.0	2.0	-0.6	0.6	-0.6	-0.2	1.3	1.1	1.4	1.3
Breast cancer (self-reported)	0.4	0.5	2.0	-0.3	0.9	0.5	0.4	0.9	-0.4	1.4	-0.0
Asthma (self-reported)	0.9	1.9	8.0	2.8	0.1	-0.7	-1.5	1.1	-0.5	1.3	-0.9
Osteoporosis (self-reported)	0.5	0.6	1.7	1.3	0.2	-0.6	1.0	0.9	0.2	0.8	0.2
Osteoarthritis (self-reported)	0.9	1.1	3.8	-0.7	-1.8	-2.0	-0.5	-0.1	-0.6	-0.3	-0.9
Medication: Aspirin	0.9	1.2	2.3	1.2	-1.2	1.1	0.7	1.5	0.7	1.5	-0.3
Medication: Gliclazide	0.8	0.9	2.6	1.6	0.7	-0.9	-1.2	-0.7	0.3	-0.4	-1.0
Illnesses of father: None of the above (group 1)	0.7	0.8	4.0	0.3	0.5	2.0	-0.6	-0.7	-0.3	-0.9	0.8
Smoking status: Current	0.3	0.4	1.5	0.6	-1.2	-0.8	0.2	0.6	0.5	0.1	-0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.6	1.2	3.0	1.1	-1.7	-1.7	-0.1	-0.5	-0.4	-0.6	1.3
Whole body water mass	0.3	1.6	3.7	-0.7	-1.9	1.5	1.3	-0.2	1.8	-0.6	-1.2
Leg predicted mass (right)	0.2	1.3	5.1	-0.7	-2.2	0.5	1.1	-0.4	1.3	-0.8	-0.9
Arm fat mass (left)	0.3	1.2	2.9	-0.0	-1.7	-0.2	-0.1	-1.1	1.3	-1.2	-1.6
Number of self-reported non-cancer illnesses	0.7	1.3	6.8	0.7	0.0	0.1	-1.2	-0.9	-2.6	-0.8	0.3
Average weekly champagne plus white wine intake	0.6	0.8	2.4	-0.2	0.2	0.3	-1.5	-1.1	-0.9	-1.4	0.2
Miserableness	0.7	1.2	3.2	0.1	-1.2	-1.6	1.0	-0.8	0.2	-0.9	1.8
Guilty feelings	1.3	1.9	3.9	-0.9	-2.0	0.2	-0.7	-1.6	-1.1	-1.8	-1.8
Wears glasses or contact lenses	0.7	0.8	4.7	-2.2	-0.5	1.0	-0.3	-0.2	-0.7	-0.2	-0.3
Ever taken oral contraceptive pill	0.6	0.7	2.0	-1.0	1.4	0.0	-0.5	-0.7	-0.6	-0.6	-0.8
Hearing aid user	0.6	0.7	2.0	-1.4	0.2	0.5	-0.4	0.2	-0.9	0.5	1.3
Mother’s age at death	0.7	0.9	1.6	0.3	0.3	1.2	-1.3	0.9	-0.1	1.1	1.3
Financial situation satisfaction	1.8	2.3	9.1	0.5	-0.9	-0.9	1.7	1.3	1.1	1.2	3.0
Tinnitus: Yes, now most or all of the time	1.9	2.2	5.0	0.5	1.4	1.4	-2.0	0.7	-2.2	1.2	1.5
Commuting to job workplace: Public transport	0.8	1.0	3.6	-1.9	-0.2	-0.0	1.1	1.2	0.4	1.1	0.5
Eye problems/disorders: Glaucoma	1.5	1.8	7.4	-0.5	-0.9	2.0	2.7	0.8	0.7	0.8	0.2
Medication: Blood pressure	0.3	0.5	1.0	-0.7	-0.7	0.1	1.0	0.7	0.6	1.0	0.6
Pain type(s) experienced in last month: Hip pain	0.2	0.3	0.8	-0.1	-0.4	-0.9	0.1	-0.9	-0.3	-0.7	0.1
Supplements: Fish oil (including cod liver oil)	1.0	1.4	3.7	0.8	-0.2	1.5	-0.4	-1.4	-0.7	-1.2	-1.9
High cholesterol (Self-reported)	0.6	1.0	3.1	-0.4	1.8	0.7	-0.7	-0.5	-1.2	-0.0	1.5
Medication: Bendroflumethiazide	0.3	0.5	1.9	-1.1	0.3	-0.3	0.2	-0.4	0.7	0.0	-1.4
Medication: Paracetamol	1.0	1.5	3.1	-1.6	-0.7	-1.8	-0.3	-1.6	-0.8	-1.7	0.2
Medication: Lisinopril	1.0	1.3	4.7	-2.2	-0.0	0.1	1.5	0.6	1.5	0.9	-0.2
Medication: Atorvastatin	0.5	0.7	2.5	0.0	0.9	0.5	-0.2	-0.4	1.3	-0.2	-1.6
Illnesses of father: High blood pressure	0.6	0.7	3.6	-0.4	-0.4	-0.7	-0.2	-0.8	0.6	-0.7	-1.9
Alcohol drinker status: Never	2.2	2.6	9.9	-0.8	0.7	-0.5	0.4	2.0	0.5	2.2	3.1
Ever smoked	0.8	1.3	6.4	0.1	0.0	0.2	0.4	-1.1	0.3	-1.7	-2.5
Basal metabolic rate	0.3	1.5	3.7	-0.7	-1.9	1.1	1.1	-0.4	1.8	-0.7	-1.3
Leg fat percentage (left)	0.6	2.0	3.9	1.0	-1.3	-0.7	-1.6	-1.9	-0.1	-2.0	-1.6
Arm fat-free mass (left)	0.3	1.5	3.3	-0.4	-1.4	1.7	0.7	-0.6	1.4	-0.9	-1.8
Number of operations (self-reported)	0.8	1.2	3.8	-0.5	0.2	-0.7	0.6	-1.6	-1.5	-2.0	-0.1
Average weekly beer plus cider intake	1.1	1.6	7.0	-0.6	-1.3	-1.3	2.6	0.9	0.0	0.6	1.1
Irritability	1.8	3.0	6.8	0.8	0.7	-0.3	-2.6	-2.4	-2.1	-2.3	-0.7
Risk taking	0.2	0.3	1.2	0.2	0.2	0.1	1.1	0.5	-0.5	0.3	0.9
Ever had prostate specific antigen (PSA) test	2.0	2.3	6.7	-1.1	0.9	1.4	-2.6	-0.4	-2.2	-0.2	-1.5
Fractured/broken bones in last 5 years	0.4	0.5	1.4	0.7	0.5	-0.1	0.6	0.6	1.2	0.2	-1.1
Age started oral contraceptive pill	0.7	0.9	3.1	0.0	0.1	1.8	0.5	1.2	-0.2	1.5	-0.3
Diastolic blood pressure, automated reading	1.0	3.0	11.4	0.5	-3.4	-0.3	1.5	-1.3	1.3	-1.7	-1.9
Ever depressed for a whole week	1.9	2.4	9.2	-0.4	-1.3	-1.4	1.7	1.4	0.5	0.8	3.0
Unable to work because of sickness or disability	0.1	0.2	0.6	0.3	-0.1	-0.4	0.7	-0.2	0.0	-0.1	0.8
Commuting to job workplace: Cycle	1.6	2.0	4.7	-1.2	0.3	0.2	1.6	1.6	0.6	2.0	2.2
Myopia	0.9	1.3	3.3	1.7	-0.0	-1.5	0.1	-1.4	0.4	-1.8	-0.6
Vascular/heart problems diagnosed by doctor	0.4	1.0	3.4	1.8	-0.3	-0.8	0.2	1.6	0.6	1.0	-0.2
Cholesterol lowering medication	0.6	0.9	2.8	1.1	0.2	-0.7	1.0	0.8	0.2	1.1	1.7
Medication: Omeprazole (e.g. Zanprol)	0.4	0.4	1.2	0.0	0.9	-1.1	-0.5	-0.0	0.5	0.4	0.9
Pain experienced in last month	0.7	1.2	3.4	-0.5	1.1	0.4	0.5	1.8	0.9	1.8	-0.3
Supplements: Calcium	1.0	1.1	2.3	1.5	0.7	-0.9	0.3	1.5	0.2	1.5	-0.6
Basal cell carcinoma (self-reported)	0.4	0.5	2.1	0.5	-0.6	0.3	1.0	0.3	0.4	-0.2	-1.4
Heart attack/myocardial infarction (self-reported)	0.7	0.8	2.8	1.7	-0.2	0.3	-1.0	-0.8	-1.4	-0.5	0.5
Deep venous thrombosis (DVT) (self-reported)	2.8	3.6	8.3	0.0	2.2	-1.0	-2.9	-2.2	-2.5	-1.8	-0.2
Heart disease (siblings)	0.5	0.6	1.5	1.2	-1.0	0.1	1.1	-0.4	0.8	-0.2	-0.3
Alcohol drinker status: Previous	0.1	0.1	0.2	0.3	-0.4	0.3	0.4	0.1	0.5	0.3	-0.1
Pack years of smoking	0.4	0.5	0.9	-0.5	-1.0	0.8	-0.4	0.9	0.1	0.8	-0.9
Impedance of whole body	0.2	0.9	4.0	-0.5	2.0	0.1	0.3	-1.0	-1.0	-1.0	-0.6
Leg fat mass (left)	0.5	1.8	3.8	0.5	-1.5	0.0	-0.9	-1.8	0.6	-1.9	-1.9
Arm predicted mass (left)	0.3	1.3	2.9	-0.1	-1.4	1.6	0.9	-0.4	1.3	-0.7	-1.7