TWAS hub - ERCC2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1170	0.0380	5.6e-04	0.110	NA	0.082	NA	0.084	2.7e-09	NA	3.1e-07	NA	2.2e-07
2	GTEx	Artery Aorta	0.1570	0.0500	1.6e-04	0.044	NA	0.049	NA	0.063	1.9e-03	NA	1.1e-03	NA	2.3e-04
3	GTEx	Esophagus Mucosa	0.1010	0.0480	9.9e-03	0.075	NA	0.060	NA	0.067	1.0e-05	NA	7.7e-05	NA	2.8e-05
4	GTEx	Esophagus Muscularis	0.1070	0.0450	5.5e-03	0.021	NA	0.001	NA	0.012	1.8e-02	NA	2.6e-01	NA	5.5e-02
5	GTEx	Heart Atrial Appendage	0.1740	0.0670	5.9e-03	0.060	NA	0.068	NA	0.068	1.1e-03	NA	5.2e-04	NA	5.5e-04
6	GTEx	Skin Sun Exposed Lower leg	0.1720	0.0430	1.8e-06	0.114	NA	0.128	NA	0.157	1.1e-09	NA	1.0e-10	NA	5.4e-13
7	TCGA	Colon Adenocarcinoma	0.0860	0.0420	7.0e-04	0.059	0.051	0.032	NA	0.034	2.6e-04	6.3e-04	5.6e-03	NA	4.4e-03
8	TCGA	Kidney Renal Clear Cell Carcinoma	0.0408	0.0204	1.2e-03	0.009	0.024	0.002	NA	0.016	3.0e-02	1.0e-03	1.6e-01	NA	5.8e-03
9	TCGA	Kidney Renal Papillary Cell Carcinoma	0.1750	0.0750	1.1e-03	0.027	0.017	0.053	NA	0.042	1.0e-02	3.5e-02	5.3e-04	NA	2.0e-03
10	TCGA	Brain Lower Grade Glioma	0.0353	0.0216	5.6e-03	0.030	0.016	0.025	NA	0.024	2.1e-04	5.4e-03	6.0e-04	NA	7.5e-04
11	TCGA	Prostate Adenocarcinoma	0.0436	0.0182	7.0e-05	0.051	0.051	0.050	NA	0.048	5.0e-06	4.9e-06	5.5e-06	NA	8.0e-06
12	TCGA	Thyroid Carcinoma	0.0720	0.0280	7.6e-08	0.070	0.082	0.056	NA	0.057	2.3e-07	2.1e-08	3.4e-06	NA	3.1e-06

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12
Osteoporosis (self-reported)	7.6	9.4	17.7	-3.3	-4.2	-3.8	-3.1	-3.4	-3.9	-2.5	-2.8	-0.2	-3.1	-2.0	-2.4
Blood Platelet Count	7.4	85.9	161.3	8.0	9.7	12.7	6.9	7.6	11.3	10.4	4.9	-8.0	7.8	10.2	10.8
Alzheimer’s Disease (including proxy)	6.4	9.2	13.7	3.6	3.5	2.9	3.4	2.0	3.7	3.1	2.9	0.0	3.6	2.6	3.2
Qualifications: A levels/AS levels or equivalent	5.6	12.5	19.9	3.6	4.4	4.5	3.7	4.2	4.3	3.0	2.4	-2.0	2.7	2.8	3.7
Current tobacco smoking	5.1	8.3	14.9	-2.9	-3.2	-3.9	-2.8	-2.8	-3.6	-2.9	-2.4	-0.5	-2.4	-2.9	-3.1
Lung cancer (father)	4.9	5.7	12.7	-2.4	-2.9	-3.6	-2.6	-2.3	-3.2	-1.7	-2.5	0.1	-2.0	-1.4	-2.2
Alzheimer’s Disease (in mother)	4.7	5.5	9.0	2.5	2.6	2.8	2.6	1.8	3.0	2.2	1.9	0.1	2.5	2.0	2.5
Smoking status: Current	4.7	7.5	14.0	-2.8	-3.0	-3.7	-2.7	-2.8	-3.4	-2.6	-2.4	-0.9	-2.1	-2.7	-2.7
Mouth/teeth dental problems: Dentures	4.6	7.8	13.1	-3.2	-3.6	-2.3	-2.5	-1.9	-3.3	-2.9	-2.1	-0.9	-3.3	-3.0	-3.2
Medication: Aspirin	4.4	5.8	10.5	-2.9	-3.2	-2.7	-2.7	-2.0	-3.0	-2.2	-1.1	0.2	-2.4	-2.2	-2.7
Fasting Glucose	4.2	5.0	9.7	-2.9	-2.4	-1.0	-2.8	-2.2	-2.4	-2.4	-0.8	-1.7	-3.1	-1.8	-2.2
Medication: Atorvastatin	4.2	5.2	9.9	-3.1	-2.4	-1.4	-2.9	-2.2	-2.8	-2.1	0.7	0.8	-3.1	-2.0	-2.2
Maternal smoking around birth	4.0	5.8	9.5	-2.8	-2.5	-2.6	-2.6	-2.7	-3.1	-2.4	-0.4	0.3	-2.7	-2.1	-2.7
Mouth/teeth dental problems	4.0	6.1	9.8	2.6	2.9	1.8	2.3	2.4	2.6	2.9	1.3	0.6	2.6	3.1	3.1
Qualifications: None of the above	3.8	8.2	19.4	-2.7	-3.2	-3.7	-3.3	-4.4	-3.2	-2.0	-1.0	1.4	-1.2	-2.6	-3.5
Fractured/broken bones in last 5 years	3.8	4.9	8.8	-2.2	-2.3	-1.9	-1.9	-2.2	-2.2	-2.6	-1.9	-0.3	-2.0	-2.9	-3.0
Diabetes (mother)	3.5	4.4	7.4	-2.1	-2.5	-2.5	-1.8	-1.3	-2.4	-2.4	-1.9	0.2	-1.3	-2.5	-2.7
Chronic bronchitis/emphysema (father)	3.4	3.9	7.3	-2.3	-2.7	-2.4	-1.7	-1.7	-2.4	-1.8	-2.4	-0.6	-1.6	-1.8	-1.6
Other serious medical condition/disability diagnosed by doctor	3.3	4.2	7.1	-2.1	-2.6	-2.5	-2.3	-2.4	-2.7	-1.9	-1.4	0.2	-1.8	-1.6	-1.9
Long-standing illness, disability or infirmity	3.3	5.1	7.8	-2.6	-2.8	-1.9	-2.5	-1.8	-2.6	-2.6	-2.2	-1.5	-2.2	-1.8	-2.0
Townsend deprivation index at recruitment	3.2	4.4	9.6	-1.4	-1.7	-3.1	-1.6	-2.5	-2.3	-2.3	-0.5	0.8	-1.2	-2.8	-3.0
Tinnitus: Yes, but not now, but have in the past	3.2	3.4	5.8	-2.0	-2.2	-2.4	-2.1	-2.3	-2.2	-1.6	-1.7	-0.5	-1.6	-1.3	-1.4
Overall health rating	3.2	6.8	9.9	-2.8	-2.9	-2.9	-2.6	-2.6	-3.1	-2.9	-1.3	0.8	-2.9	-2.6	-2.9
Average weekly beer plus cider intake	3.2	4.7	7.1	-2.3	-2.5	-2.5	-2.3	-2.6	-2.5	-1.6	-2.7	1.9	-1.7	-0.9	-1.8
Number of children fathered	3.1	3.5	5.3	1.7	2.0	2.3	1.6	1.8	1.8	1.9	2.3	1.2	0.8	2.2	2.2
Ever used hormone-replacement therapy (HRT)	3.0	3.8	7.4	-2.7	-2.0	-0.7	-2.7	-2.4	-2.0	-1.8	-0.6	-1.1	-2.5	-1.8	-1.8
Type 2 Diabetes (T2D) (2012)	2.9	3.3	10.8	0.0	0.0	0.0	0.0	0.0	0.0	-3.3	-1.7	-1.1	-2.6	-3.2	-2.8
Qualifications: O levels/GCSEs or equivalent	2.9	4.6	8.8	2.0	2.3	2.7	2.4	3.0	2.3	1.6	1.4	-2.1	0.8	1.7	2.5
Qualifications: College or University degree	2.9	9.0	15.2	3.1	3.7	3.6	3.2	3.9	3.5	2.8	1.5	-1.4	2.3	2.4	3.2
Alcohol usually taken with meals	2.8	4.5	10.5	1.9	2.1	3.2	2.1	2.5	2.6	1.8	2.0	-1.0	1.1	1.8	2.5
Age at first live birth	2.7	4.7	7.5	2.2	2.7	2.5	2.1	2.4	2.7	2.2	0.7	-1.3	2.1	1.9	2.3
Supplements: Fish oil (including cod liver oil)	2.7	3.5	5.3	-1.6	-2.1	-1.4	-1.7	-2.0	-1.7	-2.1	-2.3	-1.8	-1.1	-2.1	-2.1
Risk taking	2.7	3.9	6.1	-2.2	-2.5	-2.1	-2.3	-1.6	-2.2	-1.6	-2.4	-1.2	-1.8	-1.5	-1.9
Heel bone mineral density (BMD) T-score, automated (left)	2.6	6.0	12.5	2.4	2.8	2.3	1.4	1.1	2.5	2.4	3.5	2.9	1.9	2.7	2.5
Medication: Aspirin	2.6	3.3	7.5	-2.1	-2.7	-2.4	-1.8	-1.4	-2.4	-1.3	-0.9	0.7	-1.6	-1.4	-1.9
Severe depression (siblings)	2.5	2.8	4.6	-2.0	-1.9	-1.0	-1.9	-1.8	-1.7	-2.0	-1.6	-1.1	-2.1	-1.5	-1.2
Migraine (self-reported)	2.5	3.1	5.0	1.9	2.1	1.5	1.9	1.7	1.8	1.8	2.2	0.9	1.1	1.6	2.0
Knee pain experienced in last month	2.5	4.0	7.7	-1.9	-1.8	-1.6	-1.6	-1.9	-1.8	-2.5	-1.9	-1.7	-1.5	-2.8	-2.4
Supplements: Calcium	2.5	2.8	3.8	-1.9	-1.9	-1.1	-1.8	-1.9	-1.7	-1.6	-1.5	-0.8	-1.9	-1.7	-1.7
Heart disease (siblings)	2.5	3.1	4.7	-1.9	-2.2	-1.8	-1.8	-1.9	-2.2	-1.6	-0.7	1.1	-1.6	-1.6	-2.1
Unable to work because of sickness or disability	2.4	3.1	8.5	-1.6	-1.4	-0.8	-0.9	-0.5	-1.6	-2.6	-0.7	-0.2	-2.1	-2.9	-2.9
Neuroticism (2016)	2.3	3.3	7.7	1.8	1.5	1.1	2.6	2.5	1.8	1.6	0.4	2.8	2.0	1.0	1.2
Depression (self-reported)	2.2	2.6	4.3	-1.8	-1.9	-1.7	-1.2	-0.6	-2.0	-1.6	-1.7	1.3	-2.1	-1.4	-1.8
Hearing difficulty/problems with background noise	2.1	3.4	6.1	2.0	2.5	2.2	2.0	1.8	2.3	1.3	1.7	-0.0	1.4	1.5	1.9
Average weekly champagne plus white wine intake	2.1	2.9	5.1	1.5	1.9	2.1	1.3	0.8	2.0	1.8	1.8	-1.8	1.2	1.3	2.3
Pain type(s) experienced in last month: Hip pain	2.1	2.6	4.5	-1.9	-1.7	-1.3	-1.9	-1.8	-1.8	-1.8	-0.4	-0.2	-1.6	-1.6	-2.1
Ulcerative Colitis	2.0	2.9	5.7	-2.2	-2.4	-2.0	-1.9	-1.4	-2.3	-1.4	-1.5	-0.4	-1.8	-0.7	-1.3
Supplements: Glucosamine	2.0	2.6	8.0	-1.7	-1.2	-0.1	-1.6	-1.2	-1.2	-1.9	-1.3	-2.8	-1.7	-1.8	-1.3
Health satisfaction	2.0	2.5	4.5	-1.7	-1.7	-0.7	-1.3	-1.4	-1.3	-2.1	-1.8	1.8	-1.6	-1.5	-1.8
Mineral and other dietary supplements	2.0	2.7	5.0	1.6	1.7	0.5	1.8	1.6	1.3	1.7	1.9	2.2	1.6	1.5	1.6
Chronotype (morning person)	1.9	4.4	7.6	2.4	2.8	1.9	1.7	1.0	2.4	2.6	2.4	0.4	2.1	2.1	2.1
Illnesses of mother	1.9	2.3	4.5	-1.2	-1.5	-2.1	-1.2	-1.2	-1.8	-1.5	-2.0	-0.5	-1.1	-1.8	-1.6
Breastfed as a baby	1.9	2.4	5.9	-1.4	-1.4	-1.2	-1.4	-0.8	-1.7	-2.2	-0.1	-1.1	-1.8	-2.4	-1.7
Seen a psychiatrist for nerves, anxiety, tension or depression	1.9	2.5	3.8	-1.9	-1.8	-1.3	-1.4	-1.1	-1.9	-1.9	-0.8	0.6	-2.0	-1.6	-1.9
Pack years of smoking	1.9	2.7	5.5	-2.0	-1.7	-1.0	-1.9	-0.9	-1.8	-1.8	0.1	0.1	-1.9	-2.2	-2.3
Hand grip strength (left)	1.8	4.7	9.0	2.4	2.4	1.5	0.8	0.7	2.3	2.4	2.1	1.9	2.6	2.7	3.0
Reason for reducing amount of alcohol drunk: Health precaution	1.8	2.1	3.8	1.4	1.4	0.9	1.6	1.1	1.3	2.0	1.6	0.6	1.4	2.0	1.4
Forced expiratory volume in 1-second (FEV1), predicted	1.8	3.8	8.3	2.4	2.9	2.2	2.1	1.6	2.4	1.3	2.0	-0.1	1.5	1.4	2.0
Worrier / anxious feelings	1.7	3.1	5.5	2.1	1.9	1.4	2.3	1.6	2.2	1.7	0.2	-0.3	2.2	1.7	2.1
Medication: Ventolin 100micrograms inhaler	1.7	2.2	7.6	-1.5	-0.4	1.8	-1.6	-1.4	-0.0	-1.6	0.1	-2.8	-1.8	-1.4	-0.8
Emphysema/chronic bronchitis	1.7	1.9	3.3	-1.5	-1.4	-0.8	-1.4	-1.4	-1.2	-1.8	-1.6	-0.4	-1.1	-1.8	-1.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.7	2.0	4.5	1.6	1.8	1.2	1.9	2.1	1.5	0.9	1.1	0.2	1.2	0.9	1.5
Illnesses of siblings: Diabetes	1.7	2.0	3.3	-1.8	-1.8	-1.2	-1.6	-0.6	-1.8	-1.0	0.3	1.3	-1.7	-1.3	-1.7
Blood Red Count	1.6	15.1	31.8	-3.4	-4.3	-5.6	-3.0	-2.9	-4.9	-4.0	-4.0	1.9	-3.1	-3.7	-4.5
Heel bone mineral density (BMD) T-score, automated (right)	1.6	3.8	14.3	1.8	2.2	2.0	1.2	1.2	1.9	1.6	3.8	1.7	1.1	1.6	1.7
Falls in the last year	1.6	2.1	5.4	-1.4	-1.4	-0.9	-1.1	-0.9	-1.4	-1.9	-1.0	0.1	-1.5	-2.0	-2.3
Smoking Status	1.5	3.6	7.7	-2.0	-2.1	-2.8	-2.1	-2.3	-2.4	-1.6	-1.4	1.1	-1.3	-1.2	-1.7
Pack years adult smoking proportion	1.5	2.3	4.5	-1.8	-1.6	-1.0	-1.7	-0.9	-1.7	-1.7	0.2	0.3	-1.7	-2.0	-2.1
Medication: Atenolol	1.5	1.9	3.8	-1.8	-1.6	-1.5	-1.6	-1.1	-2.0	-1.1	0.3	1.4	-1.7	-0.6	-0.9
Fluid intelligence score	1.5	3.2	6.2	1.6	2.2	2.5	1.4	2.3	2.0	1.4	0.8	-1.9	1.2	1.6	1.9
Father’s age at death	1.5	2.1	3.9	1.0	1.6	2.0	1.1	1.5	1.6	1.5	0.8	-1.6	0.5	1.4	2.0
Ever depressed for a whole week	1.5	1.9	5.2	1.7	1.6	-0.7	1.7	1.6	0.8	1.2	0.2	2.3	1.9	0.1	0.3
Deep venous thrombosis (DVT) (self-reported)	1.5	2.0	4.9	-1.6	-1.4	-1.2	-1.1	-0.7	-1.5	-1.7	-0.3	-0.3	-1.6	-1.9	-2.2
Prospective memory result	1.4	1.7	5.5	-1.2	-1.2	-1.9	-1.9	-2.3	-1.5	-0.8	-0.2	0.8	-0.8	-0.6	-0.7
Comparative body size at age 10	1.4	3.8	7.4	2.1	2.0	1.5	1.5	1.3	2.2	2.0	1.6	1.0	2.1	2.6	2.7
Pulse wave peak to peak time	1.4	1.6	3.5	1.7	1.9	0.8	1.5	0.9	1.5	1.3	0.9	0.2	1.8	0.6	0.8
Illnesses of father: Heart disease	1.4	1.9	3.5	-1.5	-1.6	-1.9	-0.7	-0.9	-1.6	-1.4	-1.9	1.8	-0.9	-0.5	-1.1
Guilty feelings	1.4	2.1	3.4	1.6	1.3	1.1	1.4	1.0	1.7	1.8	1.0	1.1	1.9	1.5	1.6
Eye problems/disorders: Glaucoma	1.4	1.6	4.9	-1.1	-1.0	-0.4	-0.6	-0.6	-1.0	-1.9	-0.1	-1.3	-1.4	-2.2	-1.7
Verbal and Numeric Reasoning (VNR)	1.3	3.1	7.9	1.5	2.1	2.1	1.7	2.8	1.8	1.3	0.6	-1.8	0.9	1.5	1.8
Heel T-Score	1.3	10.4	34.1	2.4	3.0	2.8	1.9	0.6	2.8	2.7	4.7	5.8	1.9	3.3	3.6
Ever unenthusiastic/disinterested for a whole week	1.3	1.6	5.5	1.4	1.1	-1.0	1.5	1.1	0.6	1.2	-0.2	2.3	1.9	0.9	0.8
Exposure to tobacco smoke at home	1.3	1.5	2.5	-1.6	-1.4	-0.5	-1.0	-1.2	-1.1	-1.4	-0.7	-1.3	-1.3	-1.6	-1.1
Exposure to tobacco smoke outside home	1.3	1.8	4.7	-1.1	-1.3	-1.2	-0.6	-0.7	-1.2	-2.0	-1.0	-0.3	-0.8	-2.2	-2.0
Chest pain or discomfort	1.3	1.9	5.3	-0.8	-0.6	-0.9	-1.1	-1.6	-1.2	-2.3	1.3	-0.0	-1.2	-2.2	-1.7
Medication: Lisinopril	1.3	1.7	2.9	-1.4	-1.6	-1.5	-1.4	-0.6	-1.7	-1.2	-1.1	1.6	-1.4	-0.5	-1.1
LDL Cholesterol	1.2	2.0	4.8	1.7	1.5	0.7	1.0	0.2	1.3	1.6	2.2	0.7	1.6	1.6	1.4
Hand grip strength (right)	1.2	3.4	6.0	2.1	2.2	1.3	0.9	0.6	2.0	1.9	1.8	1.3	2.3	2.2	2.4
Taking other prescription medications	1.2	1.9	7.0	-1.3	-1.3	-1.2	-2.0	-2.6	-1.3	-1.3	-1.0	-0.3	-1.0	-0.9	-1.0
Pulse wave reflection index	1.2	1.4	2.7	-1.4	-1.6	-1.2	-1.6	-1.6	-1.4	-1.0	-0.5	0.3	-1.5	-0.5	-0.3
Blood clot in the leg (DVT)	1.2	1.6	3.7	-1.4	-1.3	-1.0	-1.1	-0.6	-1.4	-1.6	-0.3	-0.2	-1.4	-1.6	-1.9
Had major operations	1.2	1.5	6.8	1.1	1.3	1.7	0.3	-0.1	1.5	0.5	2.6	-0.6	1.0	0.2	1.0
Age at last live birth	1.2	1.8	3.4	1.2	1.5	1.2	1.5	1.9	1.4	1.4	0.5	0.1	1.2	1.4	1.7
Back pain experienced in last month	1.2	1.7	4.5	-0.9	-1.0	-2.0	-1.4	-2.1	-1.3	-1.3	-1.0	0.8	-0.6	-1.1	-1.2
Blood White Count	1.1	7.8	48.7	1.0	2.1	2.1	0.8	2.8	1.8	3.2	-0.6	-7.0	1.4	2.2	2.5
Number of treatments/medications taken	1.1	1.9	4.6	-1.8	-1.6	-0.4	-2.1	-2.1	-1.3	-1.2	-0.3	-0.9	-1.8	-0.6	-0.6
Medication for pain relief, constipation, heartburn	1.1	1.9	4.1	1.6	2.0	1.7	1.5	1.4	1.8	0.4	0.3	-1.8	1.5	-0.1	0.5
Medication: Seretide 50 evohaler	1.1	1.2	2.7	-1.4	-1.1	-0.5	-1.5	-1.3	-1.1	-1.1	0.4	-0.2	-1.6	-1.1	-0.9
Friendships satisfaction	1.1	1.4	2.6	1.4	1.6	1.2	1.5	1.3	1.6	0.9	-0.2	0.8	1.4	0.3	0.7
Osteoarthritis (self-reported)	1.1	1.4	2.8	-1.1	-1.4	-1.0	-0.7	-0.7	-1.3	-1.5	-1.1	-0.0	-1.0	-1.7	-1.7
Intelligence (Savage-Jansen 2018)	1.0	2.9	5.2	1.5	2.3	2.2	1.6	2.1	1.8	1.1	1.6	-2.1	0.7	1.2	1.7
Schizophrenia (2018)	1.0	2.1	3.8	-1.8	-1.8	-1.4	-1.4	-0.7	-1.8	-1.6	-0.5	0.0	-1.5	-1.6	-1.9
Hair/balding pattern: Pattern 2	1.0	1.2	2.4	1.4	1.6	0.9	0.7	0.2	1.3	1.1	1.2	-0.0	1.5	1.0	1.3
Medication: Ramipril	1.0	1.3	3.8	0.6	0.8	0.9	0.6	0.6	0.9	1.0	1.9	1.8	0.6	1.2	1.6
Illnesses of siblings	1.0	1.5	2.6	1.3	1.3	1.0	1.6	1.5	1.4	0.9	-0.3	-1.2	0.8	0.9	1.6
Pulse wave Arterial Stiffness index	1.0	1.2	2.7	-1.5	-1.6	-0.5	-1.3	-0.8	-1.2	-1.1	-0.8	0.0	-1.6	-0.4	-0.7
Trunk predicted mass	1.0	5.5	8.2	2.3	2.4	1.9	2.3	2.4	2.5	2.9	1.7	1.9	1.9	2.9	2.9
Tense / ‘highly strung’	1.0	1.7	3.6	-1.4	-0.9	-0.4	-1.6	-1.9	-1.0	-1.9	-1.1	-0.6	-1.7	-1.2	-1.0
Mouth/teeth dental problems: Bleeding gums	1.0	1.2	2.2	-1.1	-1.2	-0.9	-0.7	-0.7	-1.2	-1.4	-0.8	0.5	-1.3	-1.5	-1.4
Birth weight	1.0	2.1	3.5	-1.7	-1.2	-0.5	-1.9	-1.8	-1.2	-1.9	-0.1	-1.3	-1.3	-1.7	-1.5
Body fat percentage	1.0	3.8	8.7	-2.7	-2.2	-0.1	-2.4	-1.4	-1.8	-2.2	-0.1	-0.6	-3.0	-1.9	-2.1
Mouth/teeth dental problems: Loose teeth	1.0	1.1	2.6	-1.0	-0.9	-0.9	-1.1	-1.3	-1.0	-1.0	-0.1	0.9	-0.6	-1.6	-1.6
Alcohol intake frequency.	1.0	2.3	5.1	-1.3	-2.2	-2.3	-1.0	-1.1	-1.9	-1.3	-0.9	1.6	-1.1	-1.4	-1.6
Ever had prostate specific antigen (PSA) test	1.0	1.2	2.8	1.1	1.1	1.1	0.8	0.4	1.2	1.1	1.7	0.8	1.2	1.2	1.1
Rheumatoid Arthritis	0.9	1.3	3.9	1.1	1.0	1.6	2.0	1.8	1.4	0.3	0.2	-0.5	0.9	0.3	0.4
Schizophrenia (2014)	0.9	2.1	4.2	-1.6	-1.5	-1.3	-1.3	-0.8	-1.7	-1.8	-0.4	0.6	-1.5	-1.8	-2.1
Medication: Metformin	0.9	1.3	2.8	-1.4	-1.7	-1.2	-1.2	-0.4	-1.4	-0.7	-1.2	0.4	-1.4	-0.9	-0.9
Diabetes (father)	0.9	1.2	5.1	0.9	1.2	0.8	1.9	2.3	0.9	0.2	0.6	0.7	0.6	-0.1	0.4
Trunk fat percentage	0.9	3.6	7.1	-2.6	-2.1	-0.3	-2.2	-1.4	-1.7	-2.3	-0.4	-0.7	-2.7	-2.0	-2.2
Serious illness, injury or assault to yourself	0.9	1.1	2.8	-0.7	-0.8	-1.2	-0.3	-0.3	-1.2	-1.7	-0.5	0.8	-0.9	-1.6	-1.5
Impedance of arm (right)	0.9	4.2	10.3	-1.8	-1.8	-1.0	-1.5	-1.7	-1.5	-2.5	-1.1	-2.9	-1.4	-3.2	-2.7
Trunk fat-free mass	0.9	5.4	8.4	2.3	2.4	1.9	2.2	2.3	2.4	2.8	1.6	1.9	1.8	2.9	2.9
High blood pressure (siblings)	0.9	1.3	2.7	-1.4	-1.2	-0.7	-1.2	-0.7	-1.4	-1.4	-0.6	-0.3	-1.4	-1.2	-1.7
Mean time to correctly identify matches	0.9	1.7	3.9	-1.5	-1.5	-1.3	-1.4	-0.8	-1.6	-1.0	-2.0	-0.2	-1.0	-0.8	-1.5
Heart disease (mother)	0.9	1.1	2.6	-1.3	-1.3	0.1	-1.6	-1.5	-0.9	-1.1	0.1	0.1	-1.3	-0.5	-0.7
Pulse rate, automated reading	0.9	2.9	4.6	-1.6	-1.4	-1.4	-2.1	-1.6	-1.6	-1.6	-1.9	-2.0	-1.8	-1.4	-1.5
Ever had stillbirth, spontaneous miscarriage or termination	0.9	1.0	3.7	-0.7	-0.7	-1.6	-0.8	-0.9	-1.0	0.4	-1.0	1.9	0.2	0.7	-0.3
Tinnitus: Yes, now most or all of the time	0.9	1.0	3.1	1.4	1.3	0.3	1.0	0.4	0.9	0.8	1.8	0.5	1.3	0.8	0.6
High cholesterol (Self-reported)	0.9	1.6	6.5	0.7	0.8	1.1	0.9	0.9	0.8	0.9	2.2	2.5	0.6	1.1	0.8
Ever smoked	0.9	1.5	2.3	-1.3	-1.1	-1.5	-1.1	-1.3	-1.4	-1.3	-0.6	1.2	-1.0	-1.2	-1.5
Diastolic blood pressure, automated reading	0.9	2.7	7.7	-1.5	-1.7	-1.6	-1.9	-1.7	-1.7	-1.5	-1.2	2.8	-1.2	-0.7	-1.3
Bipolar Disorder or Schizophrenia	0.8	1.9	3.5	-1.9	-1.8	-1.3	-1.3	-0.2	-1.8	-1.2	-0.4	0.2	-1.7	-1.3	-1.7
Ulcerative Colitis (UC)	0.8	1.4	2.8	-1.5	-1.7	-1.4	-1.2	-0.7	-1.6	-1.0	-1.1	-0.2	-1.4	-0.7	-1.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.8	1.1	3.6	-0.9	-0.9	-0.8	-0.1	0.1	-0.8	-1.3	-1.9	0.3	-1.0	-1.5	-1.3
Hayfever, allergic rhinitis or eczema	0.8	1.8	7.7	0.5	1.0	2.5	0.8	1.7	1.5	0.3	0.6	-2.8	0.3	0.1	0.6
Hayfever/allergic rhinitis (self-reported)	0.8	1.1	2.4	0.9	1.3	1.5	0.7	0.8	1.4	1.1	0.6	-1.1	0.9	0.8	0.9
Arm fat percentage (right)	0.8	3.3	7.9	-2.5	-2.0	-0.3	-2.1	-1.2	-1.7	-2.0	0.5	-0.5	-2.8	-1.9	-2.1
Leg fat percentage (right)	0.8	2.8	8.1	-2.4	-1.8	0.5	-2.2	-1.0	-1.5	-1.8	0.4	-0.6	-2.8	-1.3	-1.6
Worry too long after embarrassment	0.8	1.4	2.8	1.2	0.9	-0.1	1.3	0.6	0.9	1.7	0.4	1.2	1.4	1.6	1.6
Alcohol drinker status: Previous	0.8	0.9	2.3	-0.9	-0.7	0.0	-0.8	-1.5	-0.5	-1.0	0.7	-1.2	-0.9	-1.5	-0.9
Primary Biliary Cirrhosis	0.7	0.9	1.5	-1.0	-1.1	-0.7	-0.8	-1.0	-0.9	-1.1	-0.3	1.2	-0.9	-1.1	-1.2
Frequency of depressed mood in last 2 weeks	0.7	1.0	3.5	-0.9	-1.0	-0.8	-0.4	-0.3	-0.8	-1.3	-1.9	0.4	-1.0	-1.0	-0.8
Hearing difficulty/problems: Yes	0.7	1.1	2.7	1.2	1.3	0.2	1.4	0.7	0.7	0.3	1.6	1.6	1.1	-0.2	-0.2
Allergy	0.7	1.6	8.6	0.0	-0.7	-2.2	-0.4	-1.5	-1.1	0.6	-0.3	2.9	0.2	0.9	0.4
Birth weight of first child	0.7	1.3	3.0	1.6	1.7	1.1	1.3	0.5	1.5	0.2	1.4	-0.7	1.4	-0.3	0.1
Glaucoma (self-reported)	0.7	0.9	3.0	-0.5	-0.8	-0.4	-0.4	-0.6	-0.6	-1.6	-0.3	-1.1	-0.6	-1.7	-1.3
Arm fat-free mass (right)	0.7	3.4	6.5	1.7	1.9	1.5	1.5	1.6	1.9	2.3	1.2	1.7	1.3	2.5	2.4
Average weekly red wine intake	0.7	1.1	2.4	0.7	1.1	1.6	1.0	1.3	1.1	1.0	0.5	-0.7	0.2	1.3	1.2
Qualifications: nursing, teaching	0.7	1.0	4.8	0.4	0.8	1.7	0.8	1.4	0.7	-0.5	0.4	-2.2	-0.2	-0.3	-0.2
Illnesses of father: High blood pressure	0.7	0.8	1.9	0.7	0.9	1.4	0.8	1.2	0.9	0.5	1.4	1.0	-0.1	0.7	0.6
Depression (Nagel 2018)	0.6	0.9	3.3	-1.1	-1.1	-0.1	-0.4	-0.1	-0.6	-1.4	-1.8	0.1	-1.0	-1.1	-0.9
BMI	0.6	3.4	6.0	-2.3	-2.1	-1.6	-1.7	-0.5	-2.3	-2.0	-0.9	1.2	-2.5	-1.8	-2.3
Allergy or Eczema	0.6	1.5	7.5	0.2	1.0	2.3	0.4	1.2	1.3	0.1	0.4	-2.7	0.1	-0.1	0.3
Ever had hysterectomy (womb removed)	0.6	0.6	1.9	-0.7	-0.9	-1.4	-0.5	-0.4	-1.2	-0.6	-0.4	0.0	-0.5	-0.7	-1.1
Systolic blood pressure, automated reading	0.6	1.8	5.9	-1.3	-1.5	-0.6	-1.1	-1.1	-1.2	-1.4	0.0	2.4	-1.3	-1.1	-1.5
Medication: Co-codamol	0.6	0.7	1.4	-1.0	-0.5	-0.1	-0.9	-1.2	-0.7	-0.7	0.8	-1.1	-1.0	-0.5	-0.7
Age when periods started (menarche)	0.6	1.4	3.4	-1.1	-1.1	-0.9	-1.1	-1.2	-1.1	-1.5	-0.9	0.1	-1.0	-1.9	-1.5
Noisy workplace	0.6	0.8	3.5	-0.6	-0.9	-0.8	-0.9	-1.9	-0.8	-0.6	0.3	1.3	-0.5	-0.2	-0.7
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.6	2.7	-0.3	0.0	-0.8	0.4	0.6	-0.7	-1.1	0.4	0.0	-0.8	-1.6	-1.1
Medication: Lansoprazole	0.6	0.7	2.6	-0.9	-0.6	-0.5	-0.7	-1.6	-0.7	-0.9	0.8	-0.0	-0.7	-1.0	-0.8
Length of working week for main job	0.6	0.7	2.1	-0.8	-0.6	-0.9	-1.0	-0.8	-0.7	-0.6	-1.5	-0.1	-0.5	-0.9	-0.9
Loud music exposure frequency	0.6	0.7	1.3	-0.9	-0.8	-0.2	-1.1	-1.0	-0.8	-0.8	0.4	1.1	-0.9	-0.3	-1.0
Arm predicted mass (right)	0.6	3.3	6.8	1.6	1.8	1.5	1.5	1.6	1.8	2.3	1.1	1.7	1.3	2.6	2.5
Family relationship satisfaction	0.6	0.8	2.2	-0.6	-0.5	-1.1	-0.2	-0.2	-0.8	-0.8	-1.5	1.2	-0.1	-1.0	-1.1
Illness, injury, bereavement, stress in last 2 years	0.6	0.7	2.7	0.3	0.4	1.5	-0.7	-0.3	1.0	0.7	0.7	-1.6	0.7	0.1	0.4
Smoking status: Previous	0.6	0.9	4.6	0.3	0.9	1.0	0.2	0.1	0.8	0.9	1.4	2.1	0.4	1.0	0.5
Arm fat percentage (left)	0.6	2.4	6.2	-2.2	-1.8	-0.1	-1.9	-1.0	-1.5	-1.7	0.4	-0.5	-2.5	-1.5	-1.7
Mood swings	0.6	1.1	2.0	-1.3	-1.2	-1.1	-1.1	-1.4	-1.2	-1.0	-0.3	0.5	-1.2	-0.8	-0.8
Eye problems/disorders: Cataract	0.6	0.7	2.3	0.6	0.3	1.5	0.8	0.8	1.1	0.7	-0.5	-0.6	0.7	0.8	0.7
Medication: Gliclazide	0.6	0.7	1.8	-1.3	-0.9	-0.1	-1.4	-0.4	-0.8	-0.4	-0.7	-0.3	-1.3	-0.2	-0.6
Whole body water mass	0.6	3.3	5.4	1.7	1.9	1.5	1.6	1.7	1.9	2.2	1.5	1.6	1.3	2.3	2.3
Wears glasses or contact lenses	0.6	0.7	4.0	-0.2	0.1	0.9	0.7	2.0	-0.1	-0.3	0.5	-1.1	-0.7	-0.7	-0.7
Financial situation satisfaction	0.6	0.8	2.8	0.8	0.7	0.0	1.4	1.2	0.6	0.6	-0.2	1.7	0.9	0.4	0.3
Leg fat percentage (left)	0.6	2.2	6.8	-2.1	-1.6	0.5	-2.0	-0.8	-1.3	-1.6	0.5	-0.6	-2.6	-1.0	-1.3
Arm fat-free mass (left)	0.6	2.9	5.3	1.4	1.7	1.6	1.3	1.4	1.8	2.2	1.3	1.7	1.0	2.3	2.2
Age started oral contraceptive pill	0.6	0.7	1.5	-1.2	-0.9	-0.6	-0.7	0.1	-1.1	-0.8	-0.9	-0.3	-1.2	-0.7	-0.8
Arm predicted mass (left)	0.6	2.9	5.2	1.4	1.6	1.7	1.3	1.5	1.8	2.1	1.4	1.8	0.9	2.3	2.2
Blood Eosinophil Count	0.5	4.0	22.1	1.0	2.0	2.2	1.0	2.8	1.6	1.3	1.5	-4.7	0.3	-0.0	0.8
Systolic Blood Pressure	0.5	2.4	5.5	-1.4	-1.1	-0.0	-1.3	-1.6	-1.1	-2.3	1.3	2.1	-1.9	-1.6	-1.7
Angina	0.5	0.7	7.0	0.3	0.0	0.2	0.4	0.4	0.2	0.3	0.4	2.6	0.3	0.3	-0.2
Vitamin and mineral supplements	0.5	0.7	1.3	0.8	1.1	0.7	0.7	0.4	0.9	0.9	1.1	0.0	0.7	0.9	1.0
Bilateral oophorectomy (both ovaries removed)	0.5	0.6	1.2	-0.9	-1.0	-0.6	-1.0	-1.1	-1.0	-0.3	0.4	0.3	-0.9	0.4	-0.1
Qualifications: CSEs or equivalent	0.5	0.6	2.3	-0.4	-0.6	-1.5	-0.4	-0.6	-1.0	-0.7	-0.8	0.9	-0.4	-0.3	-0.8
Multivitamins +/- minerals	0.5	0.6	1.3	-0.8	-0.6	-0.3	-1.0	-0.7	-0.7	-1.1	-0.3	-0.3	-0.8	-1.0	-1.0
High blood pressure (mother)	0.5	0.6	1.9	0.2	0.3	1.1	0.2	0.6	0.6	0.9	1.0	1.0	-0.1	1.4	0.9
Waist circumference	0.5	1.9	5.1	-2.0	-1.7	-0.6	-1.7	-0.9	-1.6	-1.4	-0.0	0.3	-2.2	-0.9	-1.2
Nervous feelings	0.5	1.0	2.3	-1.0	-1.0	-1.0	-0.2	-0.7	-0.9	-1.2	-1.1	-0.5	-0.8	-1.5	-1.2
Financial difficulties in last 2 years	0.5	0.7	2.4	0.9	0.8	-0.5	1.2	0.7	0.4	0.5	-0.1	1.5	1.0	0.8	0.6
Time employed in main current job	0.5	0.6	1.7	0.4	0.6	1.1	0.5	0.5	0.7	0.9	1.3	-0.4	0.0	0.9	1.1
Medication: Cholesterol lowering	0.5	0.7	2.6	0.7	0.7	0.6	0.8	0.6	0.7	0.4	1.3	1.6	1.1	-0.1	-0.2
Standing height	0.5	4.6	7.3	2.4	2.5	2.2	2.3	1.9	2.7	2.3	1.2	0.9	2.2	2.0	2.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.7	3.9	-0.2	-0.0	-0.7	0.1	0.4	-0.5	-1.3	0.0	0.4	-0.7	-2.0	-1.2
Hypothyroidism/myxoedema (self-reported)	0.5	0.9	3.6	1.0	0.7	0.4	1.4	1.9	0.8	1.0	-0.7	0.0	1.1	0.7	0.6
Number of full brothers	0.5	0.6	3.7	0.6	1.0	0.5	0.2	0.1	0.5	-0.4	1.9	-0.5	0.0	-1.0	-0.6
Wheeze or whistling in the chest in last year	0.5	0.8	1.8	-1.0	-0.9	-0.9	-1.0	-0.9	-1.0	-1.0	-0.7	0.6	-0.8	-0.7	-1.3
Medication: Blood pressure	0.5	0.9	2.3	-1.2	-0.9	-0.4	-1.5	-1.0	-1.0	-1.1	0.4	-0.1	-1.4	-0.6	-0.6
Whole body fat mass	0.5	1.9	5.6	-2.0	-1.5	0.1	-1.7	-0.8	-1.2	-1.5	0.3	0.1	-2.4	-1.1	-1.4
Whole body fat-free mass	0.5	3.1	5.0	1.6	1.8	1.4	1.6	1.7	1.8	2.1	1.4	1.7	1.2	2.2	2.2
Loneliness, isolation	0.5	0.6	1.5	-0.7	-0.9	-0.7	-0.7	-0.8	-0.6	-1.0	-1.0	0.3	-0.3	-1.2	-0.9
Number of self-reported non-cancer illnesses	0.5	0.9	5.2	0.9	1.3	0.7	0.7	0.3	0.8	0.2	2.3	1.2	0.6	0.1	0.0
Hearing aid user	0.5	0.5	2.5	-0.4	-0.8	-1.0	-0.7	-0.8	-0.6	0.2	-0.9	-1.6	-0.1	0.1	0.2
Pain experienced in last month	0.5	0.9	2.9	0.2	0.9	1.7	0.4	1.2	0.9	0.9	1.1	-0.9	-0.1	0.9	1.0
Impedance of whole body	0.5	2.3	5.8	-1.3	-1.2	-0.2	-1.2	-1.2	-1.0	-1.9	-1.0	-2.4	-1.0	-2.3	-1.9
Breast Cancer	0.4	0.9	3.8	-0.0	0.5	1.9	0.6	1.3	0.9	0.4	1.5	-0.2	-0.8	0.4	1.0
Prostate Cancer	0.4	0.5	1.5	-0.3	-0.8	-0.8	0.1	0.3	-0.6	-1.2	-1.2	0.3	-0.4	-0.8	-0.9
Triglycerides	0.4	0.7	2.3	-0.8	-1.0	-1.5	-0.6	-0.5	-1.1	-0.4	-1.5	0.3	-0.3	-0.0	-0.4
Hypothyroidism (self reported)	0.4	1.0	3.1	0.9	0.6	-0.5	1.2	1.8	0.3	1.1	-1.4	0.4	1.1	1.0	0.6
Type 2 Diabetes (T2D) (2018)	0.4	0.8	1.9	-0.9	-1.4	-1.4	-0.3	0.9	-1.1	-0.1	-1.0	1.0	-0.7	-0.1	-0.1
Hair Pigment	0.4	10.9	14.7	-3.5	-3.5	-2.1	-3.6	-3.6	-3.1	-3.6	-2.9	-2.9	-2.8	-3.8	-3.8
Sensitivity / hurt feelings	0.4	0.6	4.2	-0.3	-0.9	-1.2	-0.1	-0.1	-0.5	0.5	-2.1	-0.2	0.2	0.5	0.2
Supplements: Zinc	0.4	0.4	2.2	0.1	0.5	1.5	0.2	0.5	0.7	0.2	1.0	-0.5	-0.4	0.0	0.3
Average weekly fortified wine intake	0.4	0.5	2.5	0.1	0.3	1.1	0.5	0.5	0.7	0.0	0.4	-1.6	-0.4	-0.0	0.8
Pain all over the body in last month	0.4	0.4	0.9	-0.7	-0.9	-0.7	-0.2	-0.0	-0.9	-0.8	0.5	0.3	-0.7	-0.5	-0.8
Diabetes (self-reported)	0.4	0.6	1.9	-0.9	-1.4	-1.3	-0.8	-0.3	-1.0	-0.2	-0.7	0.3	-0.6	-0.4	-0.4
Medication: Simvastatin	0.4	0.5	3.3	0.5	0.3	0.1	0.8	0.9	0.3	0.3	0.8	1.8	0.6	0.3	0.0
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	0.9	-0.5	-0.4	-0.9	-0.8	-0.7	-0.9	-0.7	-0.1	0.8	-1.0	-0.5	-0.3
Impedance of arm (left)	0.4	2.0	6.1	-1.1	-1.1	-0.3	-0.8	-1.0	-0.8	-1.8	-0.9	-2.5	-0.8	-2.3	-1.8
Hair/balding pattern: Pattern 4	0.4	1.0	3.6	0.9	0.6	0.1	0.5	0.3	0.6	1.2	0.5	1.9	1.2	1.4	1.0
Ever highly irritable/argumentative for 2 days	0.4	0.5	2.4	-0.4	-0.4	-1.2	-0.5	-1.0	-0.7	-0.4	-0.4	1.5	-0.2	-0.1	-0.7
Medication: Amlodipine	0.4	0.5	2.5	0.0	0.5	0.2	0.4	1.1	-0.2	-0.2	1.1	1.6	-0.6	-0.2	-0.4
Angina (self-reported)	0.4	0.6	6.7	0.1	-0.2	0.1	0.2	0.3	0.1	0.1	0.2	2.6	0.0	0.0	-0.4
Number of full sisters	0.4	0.5	4.2	0.5	0.7	-0.0	0.2	0.2	0.1	-0.2	0.9	2.0	0.2	-0.3	-0.7
Commuting to job workplace: Car/motor vehicle	0.4	0.5	1.3	0.7	1.1	0.8	-0.1	0.3	0.6	0.5	0.9	0.3	0.1	1.0	0.5
Hypertension (Self-reported)	0.4	1.2	4.1	-1.1	-1.2	-1.1	-1.0	-0.6	-1.4	-0.9	0.1	2.0	-1.3	-0.5	-1.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.5	1.9	-0.1	0.2	0.4	-0.2	-0.9	0.0	-1.3	0.7	0.2	-0.2	-1.4	-0.8
Ever had bowel cancer screening	0.4	0.4	1.3	-0.1	0.3	0.9	-0.5	-1.0	0.4	-0.7	0.5	-1.1	0.1	-0.9	-0.5
Breast cancer (self-reported)	0.4	0.5	0.9	-0.8	-0.8	-0.4	-0.7	-1.0	-0.6	-0.7	-0.7	-0.4	-0.6	-0.5	-0.8
Basal metabolic rate	0.4	2.4	4.0	1.3	1.5	1.4	1.3	1.4	1.6	1.8	1.5	1.7	0.8	2.0	1.9
Myopia	0.4	0.7	2.0	0.6	0.7	0.3	0.5	0.3	0.7	1.4	0.6	0.5	1.2	1.2	0.7
Vascular/heart problems diagnosed by doctor	0.4	1.2	9.0	0.8	1.0	0.9	0.7	0.1	1.2	0.4	-0.4	-3.0	0.9	-0.1	0.6
Cholesterol lowering medication	0.4	0.7	2.6	-1.1	-0.8	-0.2	-0.7	-0.4	-0.8	-0.4	0.8	1.6	-1.0	-0.2	-0.6
Basal cell carcinoma (self-reported)	0.4	0.5	3.5	0.2	-0.4	-1.1	-0.0	0.2	-0.3	-0.3	-1.9	0.2	0.8	-0.2	-0.5
Alzheimer’s Disease (in father)	0.3	0.3	0.9	0.8	0.8	-0.2	0.6	0.6	0.3	0.5	0.4	-0.7	0.9	0.1	-0.0
Irritable Bowel Disease (IBD)	0.3	0.7	1.6	-1.1	-0.9	-0.9	-1.3	-0.6	-1.2	-0.6	0.2	-0.4	-0.9	-0.3	-0.6
Ovarian Cancer	0.3	0.4	4.4	0.3	0.4	-0.2	-0.1	-0.0	0.1	-0.1	-0.0	-2.1	0.2	-0.4	0.1
Crohns Disease (2012)	0.3	0.5	3.9	0.0	0.3	0.4	-0.3	0.0	0.2	-0.2	1.1	-2.0	-0.2	-0.0	0.4
Height	0.3	6.2	9.3	2.6	2.6	2.6	2.6	2.1	2.9	2.5	1.8	1.8	2.1	2.8	3.0
Cardiovascular Disease	0.3	0.9	6.4	-0.4	-0.3	-0.3	0.0	0.3	-0.7	-0.4	1.4	2.5	-0.9	0.1	-0.4
Respiratory disease	0.3	0.8	2.0	-1.0	-0.4	0.3	-0.8	-0.3	-0.5	-1.3	-0.2	-0.5	-1.2	-1.4	-1.3
Lung FEV1/FVC ratio	0.3	1.6	8.8	0.9	0.4	-0.1	1.3	1.4	0.4	1.0	1.0	3.0	1.1	1.0	0.7
Relative age of first facial hair	0.3	0.7	2.9	-0.7	-0.9	-0.3	-0.5	-0.4	-0.4	-0.8	-0.9	-1.7	-0.6	-1.0	-0.8
Fed-up feelings	0.3	0.6	2.2	-0.2	-0.5	-1.5	0.1	-0.5	-0.6	-0.6	-1.1	1.4	0.2	-0.8	-0.7
High blood pressure	0.3	0.7	5.4	-0.5	-0.7	-0.8	-0.5	-0.1	-0.9	-0.3	0.3	2.3	-0.7	0.1	-0.5
Diverticular disease/diverticulitis (self-reported)	0.3	0.3	1.5	0.4	0.2	1.1	0.3	0.2	0.7	-0.1	0.2	-1.2	0.1	0.3	0.6
Medication: Levothyroxine sodium	0.3	0.5	1.1	0.7	0.5	0.7	1.0	1.0	0.8	0.6	-0.3	0.1	0.9	0.4	0.4
Trunk fat mass	0.3	1.3	3.7	-1.7	-1.3	0.3	-1.5	-0.7	-0.9	-1.3	0.2	-0.1	-1.9	-1.1	-1.2
Number of incorrect matches in round	0.3	0.5	3.1	0.1	0.2	-1.0	-0.9	-1.7	-0.4	-0.4	0.5	-0.3	0.5	-0.7	-0.2
Had other major operations	0.3	0.3	1.2	-0.4	-0.4	-1.1	-0.5	-0.9	-0.7	-0.3	-0.3	0.1	-0.1	-0.4	-0.6
Alcohol intake versus 10 years previously	0.3	0.5	4.2	0.4	0.3	-0.4	0.4	0.3	0.2	0.5	-0.2	2.1	0.7	0.2	-0.0
Happiness	0.3	0.3	0.7	-0.5	-0.2	0.8	-0.2	-0.5	0.2	-0.6	-0.6	-0.6	-0.6	-0.8	-0.7
Asthma	0.3	0.7	3.3	0.0	0.6	1.8	0.6	1.2	0.9	-0.4	0.1	-1.1	-0.2	-0.4	-0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	0.8	2.2	1.2	1.5	0.1	0.7	0.0	0.8	1.0	0.8	0.7	0.9	1.0	1.2
Peak expiratory flow (PEF)	0.3	0.6	4.9	0.4	0.5	-1.1	0.6	0.3	-0.2	0.2	-0.0	2.2	0.7	0.2	0.0
Shortness of breath walking on level ground	0.3	0.3	1.9	0.3	0.4	1.4	0.6	0.6	0.9	-0.3	-0.2	0.5	0.3	0.1	-0.2
Medication: Omeprazole	0.3	0.4	0.9	0.8	0.7	0.9	0.7	0.2	0.8	0.1	0.8	1.0	0.4	0.1	0.3
Leg fat mass (right)	0.3	1.1	4.0	-1.6	-1.0	0.6	-1.4	-0.6	-0.8	-0.9	0.9	0.4	-2.0	-0.4	-0.7
Comparative height size at age 10	0.3	1.9	3.4	1.7	1.4	0.7	1.2	0.9	1.4	1.9	0.6	0.6	1.6	1.6	1.8
Suffer from ‘nerves’	0.3	0.4	1.4	-0.6	-0.3	-0.3	-0.2	-0.1	-0.5	-1.2	0.2	0.6	-0.8	-1.1	-0.8
Leg pain on walking	0.3	0.4	1.1	-0.4	-0.7	-0.9	-0.3	-0.6	-0.6	-0.3	-0.9	0.4	0.3	-0.4	-1.0
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.3	1.8	-0.3	-0.6	-0.7	0.1	0.1	-0.3	-0.5	-1.3	-0.2	0.3	-0.6	-0.5
Supplements: Vitamin C	0.3	0.3	2.2	0.3	0.0	0.2	0.6	1.5	0.1	-0.0	-0.3	0.7	0.1	-0.6	-0.6
Illnesses of father: None of the above (group 1)	0.3	0.4	1.1	0.7	0.6	0.6	0.4	0.5	0.6	1.0	0.6	0.6	0.4	0.7	0.5
Medication: Bendroflumethiazide	0.3	0.5	1.3	-0.8	-0.6	-1.0	-0.7	-0.4	-1.1	-0.9	0.1	-0.0	-0.7	-0.7	-0.7
Medication: Paracetamol	0.3	0.4	1.4	-0.1	-0.5	-0.7	0.3	0.0	-0.4	0.8	-0.2	1.2	0.1	1.1	0.5
Medication: Omeprazole (e.g. Zanprol)	0.3	0.3	1.2	0.3	0.3	0.4	-0.4	-1.1	0.3	-0.0	0.8	1.1	0.0	0.4	0.5
Depressed Affect (Nagel 2018)	0.2	0.4	1.2	-0.4	-0.9	-0.6	-0.4	-1.1	-0.3	-0.6	-0.9	0.5	0.1	-0.4	-0.1
Crohns Disease (2017)	0.2	0.5	3.6	0.2	0.9	0.9	-0.2	0.5	0.5	0.1	1.9	-0.6	0.3	-0.0	0.2
Major Depression (MDD)	0.2	0.2	0.9	0.3	0.3	0.2	0.4	0.5	0.3	0.9	0.9	0.0	0.0	0.4	0.1
Age at First Birth	0.2	0.3	1.7	-0.2	-0.5	0.1	-0.3	-0.1	-0.0	-0.0	-1.3	-1.0	-0.1	0.2	0.3
Body Mass Index (BMI) (2010)	0.2	0.2	1.1	-0.3	-0.3	0.2	-0.4	-0.1	-0.3	-0.1	1.0	-0.2	-0.8	0.5	0.2
Mean Putamen Volume	0.2	0.3	1.1	-0.1	-0.6	-0.4	-0.1	-0.7	-0.2	-0.6	-0.6	-1.1	-0.2	-0.5	-0.1
HbA1C	0.2	0.2	1.1	0.0	0.3	0.1	0.2	0.2	0.1	-0.7	0.0	-0.1	0.1	-1.1	-0.9
Lupus	0.2	0.3	1.4	-0.2	0.0	-0.3	-0.2	0.5	-0.3	-0.7	-0.7	0.5	-0.3	-1.2	-1.0
Waist Hip Ratio (WHR)	0.2	0.7	1.5	-1.2	-1.1	-0.6	-1.0	-0.1	-1.1	-0.4	0.4	0.2	-1.1	-0.7	-1.2
Average weekly spirits intake	0.2	0.2	0.7	-0.5	-0.5	-0.3	-0.3	0.1	-0.4	-0.9	-0.7	-0.1	-0.5	-0.6	-0.5
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	1.5	-0.1	0.1	0.3	0.1	0.1	0.1	0.3	1.2	1.0	-0.3	-0.1	0.3
Medication for hormone replacement therapy	0.2	0.3	1.5	-0.1	0.3	1.2	-0.1	-0.0	0.6	0.7	0.1	-0.7	0.1	0.4	0.2
Impedance of leg (right)	0.2	0.9	3.8	-0.8	-0.3	0.8	-0.7	-0.6	-0.3	-1.1	-0.0	-1.9	-0.7	-1.2	-1.0
Stomach or abdominal pain in last month	0.2	0.2	0.6	0.5	0.6	0.1	0.8	0.5	0.4	0.2	-0.2	0.5	0.8	-0.2	-0.6
Sitting height	0.2	1.5	3.1	1.3	1.8	1.6	1.3	1.1	1.5	0.9	1.7	0.2	0.8	0.5	1.0
Body mass index (BMI)	0.2	0.9	3.0	-1.5	-1.2	-0.3	-1.1	-0.3	-1.1	-0.8	0.4	0.9	-1.7	-0.2	-0.7
Past tobacco smoking	0.2	0.4	2.9	0.6	0.1	0.3	0.6	0.9	0.3	0.0	-0.5	-1.7	0.3	-0.2	0.2
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	1.5	0.2	0.3	0.5	1.2	0.8	0.3	-0.7	-0.3	-0.2	-0.0	-0.4	-0.2
Had menopause	0.2	0.2	0.8	-0.5	-0.3	0.4	-0.6	-0.6	-0.1	-0.1	-0.4	-0.9	0.0	-0.5	-0.4
Heart attack	0.2	0.2	0.9	-0.3	0.1	0.4	-0.5	-0.1	-0.1	-0.6	0.9	1.0	-0.4	-0.3	-0.4
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.3	1.3	0.4	0.4	-0.0	0.9	0.6	0.3	0.1	-0.3	1.1	0.4	0.3	0.5
Hair/balding pattern: Pattern 3	0.2	0.3	1.4	0.1	-0.5	0.4	0.7	1.2	0.1	0.1	0.2	-0.3	-0.5	-0.5	-0.3
Number of live births	0.2	0.3	1.2	-0.4	-0.6	-1.1	-0.3	-0.6	-0.7	-0.1	-0.5	0.8	0.2	-0.0	-0.2
Pulse rate	0.2	0.3	1.8	0.4	0.6	0.1	0.4	0.1	0.3	0.4	0.3	-1.4	0.3	0.4	0.4
Arm fat mass (right)	0.2	0.8	2.8	-1.3	-0.9	0.4	-1.0	-0.3	-0.6	-0.8	0.9	0.2	-1.7	-0.6	-0.8
Medication: Paracetamol	0.2	0.4	1.5	-0.3	-0.4	-0.5	-0.2	-0.6	-0.4	0.5	0.2	1.2	-0.1	1.2	0.6
Medication for cholesterol, blood pressure or diabetes	0.2	0.3	0.7	0.5	0.1	-0.2	0.5	0.3	0.2	0.7	-0.8	-0.7	0.4	0.6	0.6
Gout (self-reported)	0.2	0.3	1.0	0.1	0.2	-0.3	-0.5	-0.4	0.0	1.0	0.7	-0.1	0.4	0.9	0.5
Eye problems/disorders: None of the above	0.2	0.2	1.1	-0.2	-0.0	-1.1	-0.6	-0.6	-0.6	-0.3	-0.0	0.2	-0.3	-0.0	0.0
Neck or shoulder pain in last month	0.2	0.4	1.1	0.8	0.8	1.0	0.4	0.3	0.9	0.0	0.6	-0.3	0.4	0.2	0.3
Medication: Ibuprofen	0.2	0.3	0.7	-0.1	-0.2	-0.8	-0.2	0.0	-0.7	-0.4	-0.6	0.8	-0.7	-0.3	-0.3
Medication: Allopurinol	0.2	0.3	1.4	0.1	-0.1	-0.3	-0.2	-0.0	-0.0	0.9	-0.5	-0.2	0.4	1.2	0.6
Leg fat-free mass (right)	0.2	1.0	1.9	0.9	1.0	0.5	0.8	0.8	1.0	1.2	0.9	1.4	0.5	1.3	1.4
Handedness (chirality/laterality): Left-handed	0.2	0.2	0.5	0.4	0.6	0.7	0.5	0.6	0.4	-0.4	0.6	-0.5	-0.3	-0.2	0.4
Diabetes diagnosed by doctor	0.2	0.4	1.1	-0.6	-1.0	-1.1	-0.4	0.1	-0.8	-0.1	-0.4	0.6	-0.5	-0.4	-0.2
Commuting to job workplace: Walk	0.2	0.2	0.8	-0.7	-0.9	-0.2	-0.4	0.0	-0.5	-0.1	-0.4	-0.4	-0.5	0.1	-0.0
Asthma (self-reported)	0.2	0.5	2.0	-0.4	0.0	1.2	0.1	0.6	0.4	-0.7	-0.4	-1.4	-0.4	-0.8	-0.5
Leg predicted mass (right)	0.2	1.0	1.9	0.9	1.0	0.5	0.8	0.8	1.0	1.2	0.9	1.3	0.6	1.3	1.4
Ever taken oral contraceptive pill	0.2	0.2	1.6	-0.3	0.1	0.4	-0.6	-0.3	0.1	0.1	-0.4	-1.3	-0.0	0.0	-0.2
Mother’s age at death	0.2	0.3	1.3	-0.0	0.1	0.6	-0.0	0.2	0.4	0.4	-0.4	-1.1	-0.3	0.5	1.0
Commuting to job workplace: Public transport	0.2	0.2	0.8	0.3	0.0	-0.0	0.8	0.2	0.4	-0.3	-0.6	0.9	0.7	-0.4	0.3
Alcohol drinker status: Never	0.2	0.3	1.0	0.1	-0.8	-0.6	0.2	-0.4	-0.1	0.7	-0.4	-0.1	0.2	1.0	0.8
Number of operations (self-reported)	0.2	0.2	0.7	-0.0	-0.0	-0.5	-0.6	-0.6	-0.2	0.4	0.8	0.8	0.3	0.5	0.2
Irritability	0.2	0.3	1.0	0.6	0.1	-0.6	0.5	-0.1	0.3	0.6	-0.9	0.2	1.0	0.6	0.6
Commuting to job workplace: Cycle	0.2	0.3	1.3	0.2	0.2	-1.1	-0.1	0.1	-0.4	0.6	-0.5	1.0	0.4	0.4	-0.2
Leg fat mass (left)	0.2	0.9	3.4	-1.4	-0.8	0.6	-1.3	-0.4	-0.7	-0.8	0.9	0.4	-1.8	-0.3	-0.6
Bipolar Disorder (2018)	0.1	0.2	0.8	-0.8	-0.6	-0.2	-0.4	0.5	-0.6	0.0	-0.0	0.2	-0.9	-0.0	-0.3
Neuroticism (Nagel 2018)	0.1	0.3	0.9	0.5	0.2	0.2	0.7	-0.1	0.7	0.4	-0.3	0.5	1.0	0.7	0.9
Schizophrenia vs Biploar Disorder	0.1	0.2	0.8	0.6	0.4	0.4	0.9	0.4	0.6	0.0	0.0	0.0	0.5	0.0	0.0
Worry (Nagel 2018)	0.1	0.2	0.9	0.1	0.4	0.8	0.7	0.3	0.6	-0.3	0.2	-0.9	0.1	-0.1	0.4
Reaction Time	0.1	0.3	1.7	-0.6	-0.5	-0.1	-0.6	-0.2	-0.4	0.1	-1.3	-0.2	-0.3	0.4	-0.2
HDL Cholesterol	0.1	0.2	0.7	0.1	0.5	0.8	0.4	-0.1	0.4	-0.1	0.8	-0.2	-0.1	-0.4	0.0
Lung FVC	0.1	0.6	2.2	-0.5	-0.5	-0.9	-0.9	-1.5	-0.7	-0.5	-0.8	-0.4	-0.4	-1.1	-0.9
Neuroticism	0.1	0.3	1.1	0.3	-0.1	0.2	0.6	0.3	0.6	0.5	-0.7	-0.1	0.7	0.7	1.1
Tanning	0.1	0.9	2.1	-1.4	-1.3	0.0	-0.3	-0.2	-0.8	-1.2	-0.1	0.8	-1.4	-1.0	-1.1
Leg fat-free mass (left)	0.1	0.7	1.9	0.5	0.7	0.5	0.5	0.6	0.7	0.9	0.9	1.4	0.2	1.1	1.0
Relative age voice broke	0.1	0.2	0.6	0.1	0.1	0.4	-0.0	-0.2	0.3	-0.4	0.3	0.7	0.0	-0.8	-0.7
Impedance of leg (left)	0.1	0.6	4.4	-0.4	-0.1	0.8	-0.5	-0.5	-0.0	-0.7	-0.0	-2.1	-0.4	-0.8	-0.6
Leg predicted mass (left)	0.1	0.6	1.8	0.5	0.6	0.5	0.5	0.6	0.7	0.9	0.9	1.3	0.1	1.0	1.0
Forced vital capacity (FVC)	0.1	0.3	1.3	0.5	1.1	0.1	-0.1	-1.0	0.4	-0.1	0.7	-0.2	0.3	-0.4	0.0
Neuroticism score	0.1	0.2	1.0	-0.3	-0.5	-0.5	0.1	-0.2	-0.1	-0.2	-1.0	-0.4	-0.2	-0.1	0.1
Weight	0.1	0.4	1.8	-0.4	-0.0	0.8	-0.1	0.5	0.1	0.2	0.9	1.4	-0.8	0.6	0.4
Hip circumference	0.1	0.6	2.0	-1.2	-1.0	-0.0	-1.1	-0.7	-0.8	-0.7	0.2	0.2	-1.4	0.0	-0.1
Forced expiratory volume in 1-second (FEV1)	0.1	0.5	1.6	0.9	1.1	-0.4	0.5	-0.4	0.4	0.4	0.7	1.3	0.8	0.3	0.5
Headache pain in last month	0.1	0.1	0.4	-0.1	-0.1	0.5	-0.2	-0.5	0.2	-0.3	0.2	0.6	-0.4	0.2	0.3
Chronic bronchitis/emphysema (mother)	0.1	0.1	0.3	-0.0	0.2	0.2	0.3	0.2	-0.0	-0.4	0.5	0.2	-0.4	-0.3	-0.2
Forced vital capacity (FVC), Best measure	0.1	0.3	1.7	0.7	1.3	0.1	0.2	-0.5	0.5	0.3	0.7	-0.2	0.3	0.1	0.5
Medication for cholesterol	0.1	0.2	1.5	0.4	0.2	-0.2	0.3	0.1	0.3	-0.5	-0.3	-1.2	0.2	-0.5	0.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.1	0.2	0.9	-0.1	-0.2	-0.1	0.4	1.0	-0.1	-0.2	-0.3	-0.1	-0.0	-0.3	-0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.2	0.8	0.6	0.9	0.4	0.0	0.4	0.4	0.1	0.5	-0.2	0.3	-0.1	0.3
Arm fat mass (left)	0.1	0.5	1.8	-1.0	-0.5	0.8	-0.6	0.1	-0.3	-0.4	1.1	0.5	-1.4	-0.2	-0.4
Miserableness	0.1	0.2	0.5	0.5	0.3	0.5	0.5	0.4	0.6	0.2	-0.7	-0.0	0.2	0.4	0.7
Medication: Blood pressure	0.1	0.3	2.2	-0.1	-0.1	-0.1	-0.1	0.0	-0.3	0.1	0.7	1.5	-0.1	0.4	0.2
Heart attack/myocardial infarction (self-reported)	0.1	0.1	0.7	-0.2	0.1	0.3	-0.5	-0.1	0.0	-0.4	0.6	0.8	-0.2	-0.0	-0.1
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Mouth/teeth dental problems: Mouth ulcers	0.0	0.1	0.2	0.5	-0.1	0.1	0.0	-0.4	0.2	0.1	0.3	-0.3	0.3	0.0	-0.2

Hub : Genes

ERCC2

Models

Trait associations