TWAS hub - ESYT2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0660	0.0230	7.8e-06	0.027	0.051	0.051	0.049	0.042	2.6e-04	7.5e-07	7.6e-07	1.1e-06	6.1e-06
2	GTEx	Adipose Subcutaneous	0.0760	0.0330	6.6e-03	0.004	NA	0.000	NA	0.001	1.5e-01	NA	3.5e-01	NA	2.4e-01
3	GTEx	Cells Transformed fibroblasts	0.1180	0.0360	2.6e-05	0.073	NA	0.075	NA	0.053	4.0e-06	NA	2.9e-06	NA	7.3e-05
4	GTEx	Nerve Tibial	0.1269	0.0440	2.3e-04	0.072	NA	0.069	NA	0.059	7.7e-06	NA	1.3e-05	NA	5.3e-05
5	GTEx	Pancreas	0.1640	0.0700	9.2e-03	0.007	NA	0.016	NA	0.006	1.6e-01	NA	6.9e-02	NA	1.8e-01
6	GTEx	Skin Sun Exposed Lower leg	0.1300	0.0520	6.8e-04	0.047	NA	0.009	NA	0.034	8.3e-05	NA	5.3e-02	NA	8.0e-04
7	GTEx	Spleen	0.2000	0.0800	3.6e-03	0.034	NA	-0.009	NA	0.010	4.7e-02	NA	6.7e-01	NA	1.7e-01
8	GTEx	Testis	0.5010	0.0700	5.2e-14	0.426	NA	0.303	NA	0.381	1.7e-20	NA	6.0e-14	NA	5.9e-18
9	GTEx	Whole Blood	0.0530	0.0260	5.6e-03	0.021	NA	0.026	NA	0.034	4.5e-03	NA	1.7e-03	NA	3.9e-04
10	NTR	Blood	0.0626	0.0142	0.0e+00	0.085	0.074	0.088	0.083	0.088	4.4e-26	1.1e-22	5.4e-27	2.6e-25	7.6e-27
11	ROSMAP	Brain Pre-frontal Cortex	0.1096	0.0316	5.0e-09	0.061	0.076	0.084	0.082	0.092	2.8e-08	5.4e-10	5.5e-11	9.0e-11	7.1e-12
12	TCGA	Bladder Urothelial Carcinoma	0.0240	0.0160	8.3e-03	0.034	0.023	0.002	NA	0.023	7.1e-04	4.4e-03	2.1e-01	NA	4.1e-03
13	TCGA	Head and Neck Squamous Cell Carcinoma	0.0735	0.0514	3.7e-04	0.035	0.035	0.042	NA	0.049	8.1e-05	6.8e-05	1.7e-05	NA	3.4e-06
14	TCGA	Kidney Renal Clear Cell Carcinoma	0.0346	0.0194	8.1e-04	0.019	0.011	-0.001	NA	0.008	2.6e-03	1.7e-02	4.7e-01	NA	4.1e-02
15	TCGA	Testicular Germ Cell Tumors	0.0780	0.0450	8.7e-03	0.001	0.026	0.024	NA	0.022	2.9e-01	4.1e-02	4.8e-02	NA	5.4e-02
16	TCGA	Thyroid Carcinoma	0.1120	0.0670	1.6e-04	0.032	0.044	0.052	NA	0.040	4.3e-04	3.8e-05	7.4e-06	NA	8.9e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16
Wears glasses or contact lenses	4.4	5.1	11.0	-2.5	-0.1	1.4	1.6	1.4	1.3	-1.7	-1.0	-2.7	-3.0	-3.2	-3.0	-3.3	-3.2	-2.6	-0.3
Reason for reducing amount of alcohol drunk: Health precaution	3.7	4.4	13.0	2.1	0.2	-1.6	-2.3	-1.0	-2.3	2.5	1.0	3.6	2.5	1.7	2.4	1.7	2.1	2.2	1.9
Maternal smoking around birth	3.5	5.1	14.7	-3.3	-1.4	0.2	0.5	2.5	0.5	-2.1	-2.1	-1.2	-2.7	-2.7	-1.7	-3.8	-2.6	-2.6	-2.2
Had menopause	3.4	4.2	13.8	-2.6	0.9	1.6	1.9	0.4	1.6	-1.5	0.2	-2.1	-3.0	-2.0	-2.7	-3.7	-2.5	-1.7	-1.0
Seen doctor (GP) for nerves, anxiety, tension or depression	3.4	5.3	12.2	3.5	0.6	-1.9	-2.2	-1.8	-2.3	0.2	2.1	1.2	2.8	2.0	2.6	3.4	2.6	3.0	1.9
Rheumatoid Arthritis	2.9	4.0	7.3	2.6	-1.4	-2.6	-2.6	-1.5	-2.4	1.0	-0.1	1.5	2.7	1.3	2.6	2.4	2.1	1.8	1.1
Eye problems/disorders: Diabetes related eye disease	2.8	3.1	8.9	-0.2	2.5	3.0	2.9	1.4	2.8	-1.0	1.6	-1.1	-1.9	-0.2	-2.2	-1.6	-0.6	-0.5	0.7
Number of operations (self-reported)	2.7	4.1	8.5	-2.4	0.2	1.5	2.1	0.2	2.1	-2.1	-1.2	-2.2	-2.8	-1.3	-2.0	-2.9	-2.3	-2.3	-2.2
Supplements: Vitamin C	2.5	3.0	8.1	1.9	-1.8	-2.0	-2.4	-1.2	-2.5	0.2	-0.6	1.2	2.1	0.8	2.2	2.9	1.4	1.3	0.2
Medication: Amlodipine	2.4	3.4	6.4	2.1	0.4	-1.8	-1.7	-1.3	-1.7	2.3	1.4	0.3	2.1	2.1	2.3	1.1	2.2	2.3	2.5
Type 2 Diabetes (T2D) (2012)	2.3	2.6	4.3	2.0	-0.7	-2.0	-1.9	-1.2	-1.6	1.0	0.5	1.6	2.1	0.9	1.9	1.9	1.8	2.0	1.4
Ever had hysterectomy (womb removed)	2.3	2.6	5.5	-0.8	0.2	1.2	1.4	0.4	1.7	-2.1	-0.6	-2.2	-2.4	-1.8	-2.3	-1.3	-2.1	-1.8	-1.2
Father’s age at death	2.3	3.1	7.7	-1.2	1.0	2.5	2.8	0.5	2.7	-1.9	-0.2	-1.4	-1.9	-1.1	-2.4	-1.6	-1.4	-1.6	-1.4
Sensitivity / hurt feelings	2.2	3.7	7.1	2.2	-0.3	-2.1	-2.5	-1.7	-2.7	0.7	1.0	0.2	2.6	1.6	2.4	2.5	2.3	2.3	0.9
Pain all over the body in last month	2.2	2.4	6.8	-0.6	-1.7	-0.2	-0.4	-0.5	-0.5	-1.9	-2.1	-2.4	-1.4	-2.0	-1.0	-0.8	-1.7	-1.9	-2.6
Worry (Nagel 2018)	2.1	4.5	11.7	3.4	-0.1	-1.8	-2.0	-3.3	-2.0	1.3	1.3	1.4	2.5	0.9	2.0	3.0	1.8	2.2	1.9
Number of live births	2.1	3.0	6.7	-2.0	2.4	2.5	2.3	2.6	2.2	-1.1	1.5	-0.2	-2.1	-0.2	-2.3	-1.2	-0.9	-0.5	-0.0
Commuting to job workplace: Cycle	2.1	2.5	10.3	-0.8	2.7	2.1	2.1	3.2	2.0	0.9	1.9	0.1	-0.6	1.3	-0.9	-0.4	0.4	0.3	1.1
Reaction Time	2.0	3.9	9.7	2.9	1.8	-0.2	-0.1	-0.7	-0.1	2.4	2.2	1.5	2.1	3.1	1.8	1.5	2.6	2.6	2.1
Number of full brothers	2.0	2.5	6.2	-2.3	-1.5	0.3	1.2	2.5	1.0	-1.1	-2.2	-0.7	-1.4	-0.8	-1.2	-1.9	-1.5	-2.0	-1.9
Fractured/broken bones in last 5 years	2.0	2.6	10.3	-1.8	-1.9	-0.5	-0.1	-0.5	-0.4	-1.3	-1.9	-3.2	-1.0	-1.9	-0.8	-2.3	-1.5	-1.7	-1.7
Supplements: Glucosamine	1.9	2.4	7.4	0.9	-1.2	-1.5	-1.8	-0.3	-1.6	1.4	-0.2	1.6	2.1	1.5	2.1	2.7	1.7	1.3	0.9
Alcohol intake frequency.	1.9	4.5	11.8	-1.7	1.1	1.5	1.8	-1.2	1.9	-3.1	0.0	-3.4	-2.7	-2.1	-2.6	-2.4	-2.6	-1.7	-1.5
Number of full sisters	1.9	2.3	6.1	-2.5	-0.5	1.1	1.2	1.5	1.6	-0.9	-1.3	-0.4	-1.9	-1.7	-1.8	-1.9	-1.9	-1.9	-1.0
Ever depressed for a whole week	1.9	2.3	6.2	1.2	-0.0	-1.1	-1.4	-0.2	-1.4	1.4	0.9	1.6	2.1	1.8	1.9	2.5	1.9	1.7	1.1
Medication for hormone replacement therapy	1.8	2.0	4.7	-0.7	1.3	1.3	1.4	0.1	1.4	-2.1	0.9	-1.7	-2.0	-1.4	-1.9	-2.2	-1.5	-0.7	-0.5
Hair/balding pattern: Pattern 2	1.8	2.3	6.3	-1.7	1.4	2.5	2.3	1.6	2.4	-0.6	-0.1	1.0	-2.0	-0.6	-1.6	-0.4	-1.3	-1.4	-0.8
Birth weight	1.8	4.0	8.6	-1.6	-0.9	0.9	1.0	-0.0	1.0	-2.4	-1.6	-2.9	-2.7	-2.7	-2.2	-1.9	-2.6	-2.4	-2.4
Commuting to job workplace: Car/motor vehicle	1.8	2.1	4.8	2.2	-0.1	-1.7	-1.7	-1.5	-1.7	0.5	1.1	1.1	1.7	0.8	1.9	0.8	1.7	1.9	1.0
Hearing difficulty/problems with background noise	1.7	2.7	5.1	-2.1	1.6	1.7	1.8	2.3	1.5	-1.6	1.1	-1.3	-2.1	-1.4	-2.2	-1.8	-1.6	-0.8	0.2
Worrier / anxious feelings	1.7	3.2	9.9	3.0	1.0	-0.9	-1.5	-1.8	-1.4	0.6	1.9	0.7	2.2	1.2	1.5	3.2	2.0	2.3	1.5
Allergy or Eczema	1.6	4.3	9.2	-2.4	-0.2	1.0	1.6	-0.4	1.2	-2.6	-1.2	-3.0	-2.6	-2.4	-2.3	-2.1	-2.7	-2.3	-2.3
Ever used hormone-replacement therapy (HRT)	1.6	2.0	6.8	-0.9	0.1	0.0	0.8	-0.6	0.5	-1.9	-0.4	-2.6	-1.9	-1.6	-1.5	-2.4	-1.8	-1.1	-0.7
Average weekly fortified wine intake	1.6	1.9	3.8	1.5	1.1	0.1	-0.5	-0.0	-0.7	1.9	1.6	1.0	1.5	2.0	1.2	1.5	1.9	1.8	1.7
Health satisfaction	1.6	2.1	4.2	-2.0	0.8	1.6	1.7	1.3	1.6	-1.3	-0.1	-0.6	-1.9	-0.9	-1.9	-1.1	-1.6	-1.4	-1.6
Deep venous thrombosis (DVT) (self-reported)	1.6	2.1	4.7	1.2	0.4	-0.4	-0.5	-1.2	-0.4	1.4	1.0	2.2	1.8	2.1	1.9	1.4	2.2	1.8	0.9
Bipolar Disorder (2011)	1.5	1.5	5.3	2.3	0.4	0.2	-0.5	-1.7	-0.9	0.6	0.8	1.0	1.2	1.3	0.8	1.9	1.5	1.2	1.0
Primary Biliary Cirrhosis	1.5	2.2	4.3	2.0	0.2	-1.6	-1.4	-1.2	-1.5	0.6	1.0	1.0	2.1	1.6	2.0	1.3	1.8	1.9	0.8
Diabetes (self-reported)	1.5	2.3	14.3	-0.2	-1.7	-1.2	-0.8	-0.5	-0.8	-1.1	-1.6	-3.8	-1.0	-1.8	-0.4	-1.7	-1.5	-1.3	-1.3
Neuroticism score	1.5	3.0	8.4	2.7	-0.4	-1.5	-2.0	-2.4	-1.8	0.3	0.7	0.4	2.3	0.9	1.7	2.9	1.8	1.9	1.0
Seen a psychiatrist for nerves, anxiety, tension or depression	1.5	1.9	4.2	1.9	-0.2	-1.2	-1.4	0.5	-1.5	0.2	0.7	0.7	2.1	1.2	1.9	2.0	1.9	1.6	0.9
Mean time to correctly identify matches	1.5	2.9	8.5	2.4	1.1	-0.6	-0.2	-1.5	-0.2	2.4	1.6	0.0	1.8	2.9	1.8	0.6	2.4	2.2	1.6
Townsend deprivation index at recruitment	1.4	1.9	10.3	-0.0	0.7	1.0	1.0	0.6	1.0	-3.2	0.2	-0.8	-1.6	-1.7	-1.9	-0.4	-1.5	-1.1	-1.7
Blood clot in the leg (DVT)	1.4	1.9	4.2	1.4	0.4	-0.5	-0.5	-1.1	-0.4	1.4	1.1	2.0	1.6	1.9	1.7	1.3	1.9	1.8	1.0
Hypothyroidism/myxoedema (self-reported)	1.4	2.7	7.4	-1.4	-2.6	-0.9	-0.8	1.1	-0.6	-2.0	-2.7	-1.5	-0.6	-1.8	-0.6	-0.5	-1.5	-2.0	-2.7
High blood pressure (siblings)	1.4	2.0	6.6	-0.3	-2.6	-1.5	-1.0	-0.4	-0.9	-1.5	-2.3	-1.5	-0.6	-2.0	-0.2	-0.8	-1.6	-1.5	-1.0
Average weekly red wine intake	1.4	2.0	6.1	0.8	1.5	0.7	0.3	-0.6	0.2	2.3	2.0	1.3	1.2	1.8	0.8	0.9	1.7	1.6	2.5
Tinnitus: Yes, now most or all of the time	1.4	1.7	5.6	-1.5	1.1	2.0	2.0	1.3	2.4	-0.3	0.3	-0.7	-1.3	-0.5	-1.8	-0.4	-0.7	-0.9	-0.4
Chronotype (morning person)	1.3	3.1	12.1	2.8	-0.4	-1.5	-1.7	-3.5	-1.4	1.0	0.4	1.7	1.4	0.8	2.0	1.6	1.3	1.6	2.2
Commuting to job workplace: Walk	1.3	1.4	4.0	-2.0	-1.0	0.6	0.5	-0.2	0.5	-0.6	-1.8	0.5	-1.2	-1.2	-1.3	-0.9	-1.4	-1.7	-1.3
Neuroticism (Nagel 2018)	1.2	2.8	8.6	2.5	-1.5	-2.0	-2.2	-2.9	-2.1	-0.4	-0.4	-0.3	1.9	-0.1	1.6	2.4	0.9	0.9	0.2
Blood Platelet Count	1.2	14.1	69.9	3.1	7.0	1.8	0.6	-1.6	0.1	-0.5	8.4	3.8	0.7	1.3	-0.1	4.3	2.1	4.9	5.2
BMI	1.2	6.8	15.4	-3.1	-0.5	1.5	1.8	0.9	1.7	-2.8	-1.5	-3.1	-3.7	-3.2	-2.9	-3.9	-3.1	-2.8	-2.2
Waist Hip Ratio (WHR)	1.2	5.5	13.2	-2.5	-1.0	0.6	1.3	0.3	1.0	-1.4	-2.1	-3.0	-3.1	-3.0	-2.4	-3.6	-3.5	-3.0	-1.8
Hypothyroidism (self reported)	1.2	2.9	9.6	-2.0	-2.5	-0.7	-0.3	1.4	-0.1	-1.5	-3.0	-1.4	-0.6	-1.3	-0.6	-1.0	-1.4	-2.2	-3.1
Hayfever, allergic rhinitis or eczema	1.2	2.6	4.6	-2.0	-0.7	0.7	0.9	-0.6	0.7	-1.9	-1.6	-2.1	-1.9	-2.0	-1.5	-1.3	-2.2	-2.0	-2.1
Multivitamins +/- minerals	1.2	1.6	3.5	-1.1	1.1	1.8	1.8	1.0	1.9	-0.1	0.1	0.5	-1.8	-0.8	-1.7	-1.3	-1.3	-1.1	0.3
Chronic bronchitis/emphysema (mother)	1.2	1.4	3.5	-1.5	-1.7	-0.8	-0.6	0.8	-0.7	-1.2	-1.9	-1.6	-0.5	-1.3	-0.3	-0.5	-1.2	-1.4	-1.2
Long-standing illness, disability or infirmity	1.2	1.9	11.9	-0.1	-0.3	-0.4	0.0	-1.6	-0.1	-1.5	-0.8	-3.5	-1.4	-1.4	-0.8	-1.7	-1.6	-1.1	-1.2
Eye problems/disorders: Cataract	1.2	1.4	2.7	1.2	0.7	-0.6	-0.8	0.3	-0.8	0.7	1.1	1.6	1.4	1.6	1.1	1.3	1.6	1.5	1.2
Guilty feelings	1.2	1.8	3.9	2.0	-0.6	-1.2	-1.5	-1.7	-1.4	0.7	0.2	0.8	1.8	1.1	1.8	1.7	1.6	1.4	0.2
High cholesterol (Self-reported)	1.2	2.1	6.2	1.2	1.9	-0.1	0.1	0.5	-0.1	2.5	2.0	0.6	1.2	2.2	1.0	0.5	1.8	1.8	2.1
Average weekly beer plus cider intake	1.2	1.8	4.0	-1.5	1.2	1.4	1.9	2.0	2.0	-0.8	0.4	-1.2	-1.6	-0.2	-1.5	-1.7	-0.9	-0.7	0.0
Schizophrenia (2018)	1.1	2.3	9.5	0.5	0.3	0.5	-0.1	1.8	-0.2	2.5	0.5	3.1	1.3	1.9	1.0	1.9	1.7	1.1	1.9
Fasting Glucose	1.1	1.3	5.7	0.1	1.7	1.4	2.0	-0.7	2.4	-0.1	1.3	-0.5	-0.9	0.2	-1.3	-0.8	-0.2	0.4	0.6
Type 2 Diabetes (T2D) (2018)	1.1	2.1	14.4	-0.5	-1.3	-0.9	-0.6	-0.7	-0.7	-1.4	-1.2	-3.8	-0.9	-1.6	-0.3	-1.9	-1.3	-1.2	-1.3
Frequency of depressed mood in last 2 weeks	1.1	1.6	4.1	1.2	-0.9	-1.8	-1.7	-0.8	-1.7	0.3	0.1	0.6	2.0	0.7	1.8	1.3	1.3	1.4	0.2
Diabetes (mother)	1.1	1.4	3.4	-1.3	-0.4	1.0	1.1	1.8	0.9	-0.9	-1.0	-0.6	-1.3	-1.0	-1.4	-1.9	-1.1	-1.5	-1.1
Current tobacco smoking	1.1	1.8	5.8	-0.1	-1.8	-2.4	-2.4	0.9	-2.0	-0.6	-0.8	-0.3	1.4	0.3	1.9	-0.4	0.7	0.3	-1.1
Hair/balding pattern: Pattern 3	1.1	1.6	5.0	1.5	-1.1	-2.1	-2.1	-1.9	-2.2	-0.5	-0.2	-0.2	1.0	-0.8	1.0	0.5	0.1	0.7	1.2
Pulse wave reflection index	1.1	1.4	3.7	0.3	-0.2	-0.9	-1.5	0.4	-1.6	1.3	0.6	1.9	1.1	0.4	1.4	1.4	1.0	1.2	1.5
Number of children fathered	1.1	1.3	3.5	-1.1	-0.6	0.3	0.2	1.1	-0.1	-1.1	-1.0	-1.9	-1.1	-1.8	-0.8	-1.8	-1.3	-1.2	-0.4
Pulse rate, automated reading	1.1	3.7	11.4	-1.7	-1.6	-0.5	0.0	0.4	-0.0	-2.8	-2.0	-3.4	-1.6	-2.4	-1.3	-2.4	-2.3	-2.1	-1.9
Medication: Aspirin	1.1	1.5	3.0	0.1	1.6	1.2	1.6	-0.5	1.7	-1.3	0.8	-1.7	-1.5	-0.8	-1.6	-1.4	-1.0	-0.5	-0.0
Osteoporosis (self-reported)	1.1	1.4	4.6	-1.2	0.6	1.4	1.4	0.3	1.2	-0.8	0.1	-2.1	-1.4	-0.8	-1.4	-1.2	-1.0	-1.0	-1.3
Alzheimer’s Disease (in father)	1.0	1.1	4.5	0.8	-1.1	-1.9	-1.6	-2.1	-1.7	0.4	-0.2	0.4	0.6	-0.3	1.2	0.5	0.2	0.4	0.3
Triglycerides	1.0	1.7	3.9	1.0	1.9	0.3	0.6	0.0	0.9	1.6	2.0	0.8	0.9	2.0	0.9	-0.1	1.7	1.6	1.8
Respiratory disease	1.0	2.2	5.0	-1.3	1.3	1.5	2.0	-0.1	2.1	-1.4	0.4	-0.3	-2.2	-1.3	-2.0	-1.9	-1.9	-1.0	0.0
Neuroticism	1.0	2.4	9.5	2.5	-0.8	-1.5	-1.8	-3.1	-1.7	0.4	0.1	0.4	1.8	0.3	1.3	2.6	1.1	1.1	0.8
Diverticular disease/diverticulitis (self-reported)	1.0	1.2	3.8	-0.7	-0.7	-0.0	0.6	-0.6	0.7	-1.0	-1.4	-1.2	-1.3	-0.9	-0.7	-1.9	-1.3	-1.3	-1.9
Medication: Atenolol	1.0	1.2	5.4	-0.8	1.8	1.0	1.4	2.3	1.1	0.8	1.4	-0.3	0.1	1.5	-0.1	-0.0	0.7	0.6	0.3
Waist circumference	1.0	3.8	12.1	-2.0	-1.0	0.2	0.6	0.0	0.4	-1.7	-1.6	-3.5	-2.6	-2.5	-1.8	-3.1	-2.6	-2.1	-1.0
Medication: Ramipril	1.0	1.3	3.3	0.7	-1.6	-1.8	-1.8	-0.8	-1.7	1.1	-1.2	0.3	1.1	0.2	1.5	0.8	0.6	0.3	0.1
Medication: Lansoprazole	1.0	1.1	2.4	0.3	1.4	1.6	1.4	1.3	1.2	-1.1	0.9	-1.5	-1.0	-0.1	-1.4	-0.6	-0.4	-0.4	0.0
Loud music exposure frequency	1.0	1.1	3.9	0.2	1.9	1.2	1.3	0.6	1.2	0.2	1.7	2.0	-0.3	0.5	-0.7	0.1	0.2	0.7	0.8
Medication: Ventolin 100micrograms inhaler	1.0	1.2	3.7	-0.9	1.2	1.4	1.8	-1.0	1.9	0.1	0.4	0.5	-1.3	-0.3	-1.0	-1.8	-0.9	-0.5	0.1
Comparative body size at age 10	1.0	2.7	5.5	-2.4	-0.5	0.6	0.9	1.0	0.7	-1.5	-1.0	-2.1	-1.9	-2.0	-1.6	-2.1	-2.0	-2.0	-1.8
Medication: Ibuprofen	1.0	1.2	3.0	1.5	-0.5	-1.2	-0.8	-1.5	-0.7	0.7	-0.1	0.5	1.5	1.3	1.7	0.8	1.4	1.2	0.1
Comparative height size at age 10	1.0	5.3	12.5	3.0	-1.0	-2.7	-3.2	-2.3	-3.5	1.7	0.8	-0.0	2.4	1.6	3.3	1.8	2.2	2.4	2.0
Age at last live birth	1.0	1.5	8.8	-0.0	0.5	0.5	0.4	1.6	0.3	3.0	0.3	0.7	1.4	2.1	0.7	1.4	1.1	0.5	0.3
Bipolar Disorder or Schizophrenia	0.9	2.2	6.7	1.3	0.7	0.4	0.0	0.3	0.0	2.4	0.8	2.6	1.5	2.1	1.1	1.3	1.9	1.5	2.0
Depression (Nagel 2018)	0.9	1.3	3.9	1.2	-1.1	-2.0	-1.6	-1.4	-1.8	0.3	-0.3	0.0	1.5	0.4	1.5	1.0	0.9	0.8	0.2
Crohns Disease (2017)	0.9	2.0	6.7	1.5	0.4	-0.5	-1.1	-1.7	-1.1	0.2	1.2	2.6	1.3	1.1	1.1	2.2	1.5	1.6	1.1
Height	0.9	17.5	32.3	5.2	-0.6	-5.1	-5.3	-4.0	-5.7	2.5	2.4	1.5	5.3	3.0	5.7	3.5	4.3	4.9	3.2
Lung FEV1/FVC ratio	0.9	4.5	11.4	3.4	0.6	-1.1	-1.4	-0.6	-1.1	2.1	1.8	1.2	2.6	2.4	2.1	2.6	2.6	2.6	3.0
Hearing difficulty/problems: Yes	0.9	1.4	3.4	-1.1	0.4	1.0	1.1	0.3	0.8	-1.1	0.1	-0.9	-1.8	-1.8	-1.7	-1.7	-1.8	-1.1	-0.2
Body mass index (BMI)	0.9	3.8	8.3	-2.3	-0.4	1.3	1.4	0.6	1.2	-1.7	-1.1	-2.6	-2.9	-2.4	-2.4	-2.8	-2.4	-2.2	-1.0
Alcohol usually taken with meals	0.9	1.4	3.6	0.3	1.8	0.7	0.4	0.1	0.3	1.8	1.9	1.0	0.9	1.5	0.4	0.2	1.4	1.4	1.9
Ever unenthusiastic/disinterested for a whole week	0.9	1.1	3.4	0.2	0.5	0.0	-0.2	0.5	-0.2	1.1	1.0	1.1	1.4	1.8	1.3	1.5	1.5	1.2	0.4
Illnesses of siblings	0.9	1.2	4.8	0.3	2.2	1.3	0.9	0.4	0.9	1.2	1.9	1.4	0.3	1.2	-0.1	0.4	1.0	1.1	0.8
Pulse rate	0.9	1.6	5.9	-1.7	-0.4	0.9	0.9	1.3	0.5	-1.4	-1.0	-2.4	-0.9	-0.2	-1.1	-1.2	-0.7	-1.4	-1.9
Asthma	0.9	1.8	5.4	-0.9	2.3	1.9	1.9	-0.4	1.9	-0.4	1.7	0.5	-1.7	-0.2	-1.5	-1.4	-0.8	0.1	0.9
Age at first live birth	0.9	1.5	6.9	-0.3	0.8	1.0	1.0	2.2	0.8	2.6	0.5	0.4	0.9	1.9	0.4	1.6	1.0	0.5	0.9
Shortness of breath walking on level ground	0.9	1.1	3.8	-0.3	1.9	1.1	1.3	2.0	1.2	-0.1	1.6	0.2	-0.2	1.1	-0.4	-0.3	0.6	0.7	0.6
Illnesses of siblings: Diabetes	0.9	1.1	3.1	1.4	-1.2	-1.6	-1.7	-1.8	-1.6	-0.7	-0.7	-0.5	0.3	-1.1	0.3	0.8	-0.4	-0.0	0.0
Diabetes diagnosed by doctor	0.9	1.4	14.8	0.1	-0.9	-0.8	-0.5	-0.2	-0.5	-0.5	-0.8	-3.8	-0.7	-0.9	-0.4	-1.4	-0.9	-0.8	-0.8
Smoking status: Current	0.9	1.4	4.6	-0.3	-1.6	-2.2	-2.1	1.2	-1.7	-0.4	-0.7	-0.5	1.2	0.2	1.5	-0.8	0.5	0.2	-1.1
Miserableness	0.9	1.6	4.5	1.5	-1.8	-1.5	-1.7	-1.2	-1.6	-0.3	-0.9	-0.9	1.5	0.1	1.3	2.1	0.7	0.5	-0.2
Medication: Blood pressure	0.9	1.6	4.0	0.4	-0.1	-1.6	-1.3	0.9	-1.4	2.0	0.7	0.2	1.5	1.1	1.6	0.1	1.5	1.7	1.8
Leg fat percentage (left)	0.9	3.3	7.6	-1.8	-1.2	0.1	0.4	0.4	0.1	-2.1	-1.6	-2.6	-2.3	-2.8	-1.8	-2.3	-2.5	-2.0	-1.4
Myopia	0.9	1.3	4.9	0.7	-1.3	-2.2	-1.9	1.1	-1.0	-0.6	-0.3	-1.3	1.3	0.2	1.7	0.1	0.8	0.9	-0.3
Depressed Affect (Nagel 2018)	0.8	1.7	4.0	1.4	-2.0	-1.6	-1.5	-2.0	-1.4	-1.5	-1.4	-1.7	0.8	-0.7	0.5	1.3	-0.1	-0.3	-0.9
Schizophrenia vs Biploar Disorder	0.8	1.0	9.7	-1.9	-0.3	0.8	0.5	3.1	0.4	0.2	-0.5	0.4	-0.5	-0.4	-0.4	0.3	-0.6	-0.8	-0.6
LDL Cholesterol	0.8	1.2	3.1	0.6	1.4	1.1	0.4	-0.1	0.6	1.3	1.6	0.7	0.8	1.3	-0.1	1.7	1.2	1.1	1.6
Neuroticism (2016)	0.8	1.2	5.1	0.7	-1.2	-1.9	-2.3	-1.2	-1.8	-0.9	-0.4	-0.0	0.7	-0.7	0.9	1.0	0.1	0.5	-0.5
Impedance of leg (right)	0.8	3.8	8.8	2.2	-0.6	-3.0	-2.8	-0.9	-2.7	0.5	0.8	1.8	2.7	1.0	2.6	2.0	1.7	2.2	0.8
Serious illness, injury or assault to yourself	0.8	1.0	2.9	0.3	-0.8	-1.7	-1.5	-0.5	-1.3	0.7	-0.3	-1.4	0.9	0.6	1.6	0.1	0.8	0.8	0.5
Nervous feelings	0.8	1.5	6.4	2.2	-0.6	-1.3	-1.5	-2.5	-1.5	-0.7	0.4	0.2	0.8	-0.9	0.5	1.6	-0.1	0.7	0.2
Hayfever/allergic rhinitis (self-reported)	0.8	1.0	3.3	-1.1	-1.3	-0.4	-0.2	-0.6	-0.4	-1.0	-1.8	-1.5	-0.4	-0.8	-0.1	-0.0	-0.8	-1.3	-1.7
Illnesses of mother	0.8	0.9	3.5	1.6	-1.0	-0.8	-1.2	-1.9	-1.1	-0.5	-0.9	0.6	0.4	-0.5	0.2	1.6	-0.0	0.0	0.1
Standing height	0.8	8.3	17.8	3.5	-1.1	-3.6	-3.9	-3.4	-3.9	2.1	0.8	0.3	3.5	2.0	4.2	2.5	2.9	2.9	1.8
Leg fat percentage (right)	0.8	2.9	7.4	-1.4	-1.5	-0.4	-0.1	0.0	-0.3	-2.0	-1.6	-2.5	-2.0	-2.7	-1.4	-2.2	-2.3	-1.8	-1.3
Angina (self-reported)	0.8	1.0	4.0	-0.1	2.0	1.0	0.8	0.6	0.7	0.8	1.7	-0.6	-0.0	1.2	-0.2	0.6	0.7	1.0	1.4
Suffer from ‘nerves’	0.8	1.3	3.5	1.9	-0.3	-0.9	-1.2	-1.8	-1.3	0.8	0.5	1.0	1.2	0.4	1.0	1.7	0.7	1.1	0.8
Qualifications: NVQ or HND or HNC or equivalent	0.8	1.0	5.2	0.2	2.1	0.8	0.9	0.4	1.0	-1.1	2.3	0.1	-0.7	-0.2	-0.8	-0.3	-0.1	0.9	0.8
Illnesses of father: Heart disease	0.8	1.1	4.9	-0.3	1.9	1.5	1.2	0.5	1.0	0.4	1.4	2.2	-0.4	0.4	-0.8	0.8	-0.0	0.3	0.9
Asthma (self-reported)	0.8	1.5	4.5	-0.8	2.1	1.7	1.7	-0.6	1.8	-0.1	1.6	0.8	-1.6	-0.1	-1.3	-1.3	-0.7	0.1	1.0
Financial situation satisfaction	0.8	1.0	3.6	1.2	-0.6	-1.9	-1.6	-0.1	-1.4	-0.8	0.7	-1.1	0.8	-0.2	0.7	0.9	0.5	1.3	0.7
Eye problems/disorders: Glaucoma	0.8	0.9	2.2	-0.3	0.1	1.5	1.5	0.7	1.2	-0.4	-0.6	-1.3	-0.9	-0.5	-1.4	-0.6	-0.9	-1.1	-0.5
Alcohol drinker status: Never	0.8	1.0	2.6	-0.6	1.5	1.6	1.4	0.3	1.5	-0.2	0.7	-0.5	-1.3	-0.5	-1.3	-0.8	-0.6	-0.4	0.5
Pain experienced in last month	0.8	1.3	3.5	0.5	0.4	-0.2	-0.6	0.6	-0.6	1.9	1.2	1.7	1.4	1.2	1.2	1.4	1.5	1.3	1.4
Ulcerative Colitis (UC)	0.7	1.3	3.5	0.5	-1.0	-0.3	-0.7	-0.2	-1.1	1.6	-0.7	1.2	1.3	1.9	1.5	1.3	1.8	0.8	0.4
Ovarian Cancer	0.7	1.0	5.2	-0.1	2.3	1.2	1.3	-0.0	1.1	0.2	1.7	0.6	-0.6	0.3	-0.7	-1.0	-0.1	0.2	0.8
HDL Cholesterol	0.7	1.2	2.3	1.2	0.1	-1.3	-1.3	-1.5	-1.5	0.9	0.8	0.4	1.4	0.7	1.1	1.3	0.8	1.1	1.2
Blood White Count	0.7	5.0	16.2	-1.3	-1.4	0.1	0.2	0.3	0.6	-4.0	-2.0	-2.3	-2.5	-3.8	-2.5	-0.9	-3.1	-2.6	-2.6
Average weekly spirits intake	0.7	0.9	3.2	-0.4	0.8	1.7	1.4	1.7	1.8	0.2	0.2	-0.6	-0.4	0.6	-1.0	0.6	0.1	-0.2	-0.2
Other serious medical condition/disability diagnosed by doctor	0.7	0.9	5.2	-0.0	0.2	-0.4	-0.2	-0.5	-0.2	-1.6	0.1	-2.3	-1.1	-1.1	-0.7	-1.0	-1.1	-0.4	-0.1
Angina	0.7	0.9	3.6	-0.3	1.9	1.2	1.0	0.9	0.8	0.7	1.6	-0.5	-0.1	1.1	-0.4	0.7	0.6	0.9	1.2
Severe depression (siblings)	0.7	0.8	2.0	1.1	1.1	0.2	0.1	0.0	0.1	1.2	1.1	1.4	0.6	1.0	0.7	0.3	0.8	0.9	1.2
Medication: Levothyroxine sodium	0.7	1.3	4.3	-1.5	-1.7	-0.3	-0.3	0.7	-0.4	-0.8	-1.9	-0.9	-0.5	-0.9	-0.5	-0.4	-1.1	-1.5	-2.1
Chronic bronchitis/emphysema (father)	0.7	0.8	3.0	0.4	-0.1	0.4	0.7	-0.4	0.8	-1.7	-0.5	-0.2	-1.1	-1.0	-1.0	-1.2	-1.2	-1.1	-0.7
Depression (self-reported)	0.7	0.9	3.0	1.7	-0.3	-1.1	-0.8	-1.6	-1.0	-0.9	0.2	-0.6	0.9	0.7	0.9	1.1	0.6	0.9	0.5
Prospective memory result	0.7	0.9	2.7	1.5	1.6	1.3	0.8	0.2	0.9	-0.5	1.2	0.6	-0.8	-0.7	-1.3	0.3	-0.2	0.1	0.8
Tense / ‘highly strung’	0.7	1.2	3.5	1.4	-1.3	-1.9	-1.7	-1.3	-1.4	0.5	-0.3	-0.1	1.3	0.2	1.5	0.7	0.7	0.8	-0.2
Glaucoma (self-reported)	0.7	0.8	2.2	0.2	0.4	1.5	1.4	0.1	1.3	-1.1	-0.3	-1.4	-0.8	-0.2	-1.3	-0.2	-0.5	-0.9	-0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.9	2.5	-0.9	-1.0	-0.2	0.2	-0.0	0.2	-0.3	-1.4	0.1	-0.9	-1.0	-0.9	-1.3	-1.2	-1.4	-1.6
Overall health rating	0.7	1.5	6.3	0.2	-0.3	-0.6	-0.2	-0.8	0.0	-2.5	-0.6	-2.4	-1.1	-1.4	-0.8	-1.5	-1.2	-0.8	-1.7
Chest pain or discomfort	0.7	1.0	2.7	-0.5	1.4	1.6	1.6	0.4	1.4	0.8	0.8	-0.9	-1.1	0.2	-1.1	-0.8	-0.4	-0.3	1.4
Had major operations	0.7	0.9	2.2	-1.4	0.1	1.1	1.2	0.6	1.5	-0.4	-0.7	-1.0	-1.1	-0.0	-0.7	-0.9	-1.0	-1.0	-0.8
Mood swings	0.7	1.2	4.1	2.0	-0.4	-0.7	-0.7	-1.8	-0.3	-1.9	-0.1	-2.0	0.8	-0.3	0.2	1.6	0.1	0.3	-0.5
Mouth/teeth dental problems: Mouth ulcers	0.7	1.1	4.2	-1.0	-0.7	0.6	0.4	1.1	0.5	-2.1	-1.1	-1.0	-0.6	-1.2	-1.3	-0.2	-1.0	-1.2	-1.5
Breast cancer (self-reported)	0.7	0.8	4.0	-1.1	0.3	0.5	0.6	2.0	0.4	-1.5	-0.2	-0.8	-0.5	-0.1	-0.6	-1.2	-0.3	-0.7	-1.4
Medication: Aspirin	0.7	0.9	3.2	0.5	1.8	1.2	1.4	-0.3	1.3	-0.6	1.1	-1.2	-0.9	-0.1	-1.2	-0.6	-0.3	0.0	0.4
Illnesses of father: High blood pressure	0.7	0.8	2.2	0.3	-0.8	-1.5	-1.4	0.4	-1.2	0.3	0.2	-1.1	1.2	0.2	1.5	0.4	0.7	0.9	0.5
Risk taking	0.7	1.0	4.2	-1.6	-1.3	-0.8	-0.1	0.3	-0.2	-0.2	-1.4	-1.0	-0.8	-1.0	-0.2	-2.1	-1.1	-1.2	-0.1
Diastolic blood pressure, automated reading	0.7	2.2	6.0	-1.3	-2.4	-1.2	-0.5	0.3	-0.4	-0.9	-2.2	-1.7	-0.9	-1.6	-0.4	-2.5	-1.4	-1.5	-1.9
Irritable Bowel Disease (IBD)	0.6	1.5	4.3	1.1	-0.5	-0.1	-0.8	-1.1	-1.0	0.9	-0.1	2.1	1.3	1.5	1.2	2.1	1.7	1.0	0.7
Age at First Birth	0.6	0.8	2.6	-0.6	1.3	1.6	1.4	1.0	1.5	0.8	0.7	0.4	-0.2	0.5	-1.1	0.2	0.4	-0.0	0.6
Medication: Co-codamol	0.6	0.7	1.7	-1.2	0.5	0.3	0.3	1.3	0.1	-0.6	0.4	-1.2	-1.2	-0.8	-0.9	-1.2	-0.7	-0.2	0.3
High blood pressure (mother)	0.6	0.9	3.6	-0.3	1.3	0.2	0.6	0.9	0.7	1.0	1.9	-0.2	0.5	1.1	0.6	-0.6	0.9	1.3	1.3
Impedance of leg (left)	0.6	3.1	6.3	1.9	-0.3	-2.5	-2.3	-0.5	-2.2	0.6	0.9	1.7	2.5	1.1	2.3	1.9	1.7	2.2	0.7
Heart attack	0.6	0.8	5.6	0.8	0.8	0.2	0.1	0.8	0.1	1.5	0.5	2.4	0.3	0.6	0.2	0.4	0.5	0.5	1.0
Impedance of arm (right)	0.6	2.8	6.9	2.4	1.9	-0.4	-0.5	-0.5	-0.4	0.8	2.6	1.7	1.7	1.8	1.1	2.3	1.9	2.5	1.4
Time employed in main current job	0.6	0.7	3.6	-1.6	0.5	1.0	0.9	1.9	0.7	-0.4	0.5	0.3	-0.6	-0.5	-0.7	-0.8	-0.3	-0.1	0.0
Noisy workplace	0.6	0.7	1.5	-0.5	0.5	1.1	1.1	1.1	1.1	-1.2	-0.2	-0.2	-1.2	-0.5	-1.0	-0.7	-0.8	-0.8	-0.6
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.7	1.8	0.6	1.0	-0.1	-0.3	-0.6	-0.5	0.7	1.3	-0.3	0.8	1.1	0.8	0.2	1.0	1.2	1.3
Lung cancer (father)	0.6	0.7	2.6	-1.6	-0.4	0.4	0.5	1.4	0.6	0.1	-0.5	-0.7	-0.9	-0.7	-0.8	-1.3	-1.0	-0.9	-0.4
Length of working week for main job	0.6	0.6	3.2	0.2	1.0	0.4	0.6	-0.8	0.6	0.7	1.1	1.3	-0.4	0.1	-0.2	-0.4	0.0	0.6	1.8
Headache pain in last month	0.6	1.0	4.8	2.2	-1.0	-1.1	-0.8	-1.6	-0.4	-1.4	-0.7	0.9	-0.2	-1.4	-0.0	0.2	-0.9	-0.3	-0.3
Gout (self-reported)	0.6	0.8	2.3	-0.1	-1.1	-0.3	0.0	-0.5	0.4	-0.5	-1.5	-1.4	-0.5	-1.1	-0.5	-0.8	-1.0	-1.3	-1.0
Exposure to tobacco smoke outside home	0.6	0.8	2.9	-0.2	-0.1	-1.7	-1.6	-1.0	-1.6	0.7	0.8	0.8	0.4	-0.1	0.7	-0.4	0.2	1.0	0.6
Wheeze or whistling in the chest in last year	0.6	1.1	3.2	-1.1	0.2	0.4	0.6	-1.0	1.1	-1.8	-0.2	-1.1	-1.4	-1.2	-1.0	-1.1	-1.3	-0.9	-1.0
Leg fat mass (right)	0.6	2.4	6.4	-1.2	-1.3	-0.2	0.0	-0.4	-0.1	-1.4	-1.6	-2.5	-1.9	-2.4	-1.2	-2.2	-2.0	-1.8	-1.1
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.3	3.3	-0.0	0.7	-0.4	-0.5	1.1	-0.4	1.7	1.1	1.1	1.0	1.3	1.2	1.3	1.2	1.3	1.8
Arm fat percentage (left)	0.6	2.3	5.5	-1.8	0.0	1.2	1.2	0.6	1.0	-1.1	-0.5	-2.3	-2.3	-1.8	-2.0	-2.2	-1.8	-1.5	-0.8
Back pain experienced in last month	0.6	0.8	2.8	-0.9	1.7	0.8	1.0	0.7	0.6	-1.0	1.6	-1.2	-0.6	-0.0	-0.7	-0.5	-0.3	0.5	0.7
Mineral and other dietary supplements	0.6	0.8	5.0	0.3	1.7	0.3	0.2	0.2	0.4	-0.2	2.2	1.2	-0.0	0.3	0.0	-0.6	0.6	1.2	0.2
Average weekly champagne plus white wine intake	0.6	0.8	6.2	0.7	-0.1	-0.5	-0.6	-0.6	-0.7	1.0	0.1	2.5	1.0	0.8	1.0	0.0	0.9	0.7	0.5
Mother’s age at death	0.6	0.7	3.5	-0.9	0.0	0.3	0.8	0.2	1.0	-1.0	-0.3	-1.9	-0.6	-0.7	-0.5	-1.1	-0.9	-0.8	-0.5
Pain type(s) experienced in last month: Hip pain	0.6	0.8	2.3	-0.8	1.5	1.4	1.2	1.1	1.1	0.5	0.9	-0.2	0.0	1.1	-0.3	-0.2	0.5	0.4	1.0
Supplements: Fish oil (including cod liver oil)	0.6	0.8	2.8	-1.0	-1.0	0.3	0.5	0.8	0.2	0.1	-1.7	-1.5	-0.9	-0.7	-0.8	-0.6	-1.2	-1.4	-0.2
Medication: Bendroflumethiazide	0.6	0.9	4.9	0.7	0.9	-0.5	-0.3	1.2	-0.7	0.7	1.5	-0.2	0.5	0.8	0.6	0.1	0.7	1.4	2.2
Ever smoked	0.6	1.0	2.7	-0.6	-0.3	-1.5	-1.1	1.2	-1.4	1.4	0.2	0.5	1.2	1.2	1.6	-0.5	0.9	0.7	-0.2
Pack years of smoking	0.6	0.9	4.3	-0.4	-0.2	-1.8	-0.9	-0.8	-1.1	0.2	0.5	-1.5	0.3	-0.1	0.9	-2.1	0.0	0.7	0.4
Leg fat mass (left)	0.6	2.4	6.7	-1.4	-1.2	0.1	0.3	-0.2	0.1	-1.4	-1.5	-2.6	-1.9	-2.3	-1.3	-2.2	-2.0	-1.8	-1.1
Bipolar Disorder (2018)	0.5	0.8	4.0	1.5	0.7	-0.0	0.1	-2.0	0.4	1.1	0.8	0.4	0.5	1.1	0.5	-0.2	0.9	0.9	0.9
HbA1C	0.5	0.6	1.5	-0.3	-0.5	0.8	0.3	0.2	0.4	-1.0	-0.8	-0.9	-0.9	-1.2	-1.0	-0.6	-1.2	-0.4	0.2
Lupus	0.5	0.8	4.7	1.4	-0.4	-1.1	-0.5	-2.2	-0.6	0.3	0.1	0.8	0.3	0.3	1.3	-1.0	0.0	0.6	0.6
Schizophrenia (2014)	0.5	1.2	4.2	-0.3	0.0	0.9	0.4	1.5	0.2	2.0	0.0	1.6	0.8	1.6	0.7	1.6	1.2	0.4	1.0
Blood Red Count	0.5	4.6	11.0	-2.5	1.0	2.9	2.7	2.5	2.6	-2.3	-0.3	-1.3	-2.5	-1.8	-3.3	-1.2	-2.0	-2.0	-0.9
Relative age of first facial hair	0.5	1.1	3.7	-1.9	0.5	1.0	1.0	0.8	1.0	-1.2	-0.2	-0.4	-1.1	-1.1	-1.2	-0.5	-1.2	-1.1	-1.1
Medication: Metformin	0.5	0.7	5.3	0.1	-0.4	-1.0	-0.5	-0.4	-0.6	-0.5	-0.3	-2.3	-0.4	-0.5	0.0	-1.7	-0.6	-0.3	-0.7
Pack years adult smoking proportion	0.5	0.7	2.6	-0.1	0.3	-1.5	-0.7	-0.4	-0.7	0.5	1.0	-0.7	0.6	0.4	1.1	-1.6	0.5	1.1	0.8
Fed-up feelings	0.5	0.9	2.5	0.8	-1.1	-1.3	-1.6	-0.5	-1.6	-1.0	-0.5	-0.6	0.9	-0.7	0.6	1.3	0.4	0.3	0.0
Forced expiratory volume in 1-second (FEV1)	0.5	1.8	3.8	1.9	0.1	-1.4	-1.3	-1.3	-1.1	1.3	0.8	0.9	1.5	1.4	1.7	1.4	1.7	1.6	1.1
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.6	1.6	1.3	-0.0	-0.5	-0.2	-1.0	-0.2	0.9	-0.0	0.4	0.9	1.1	1.1	0.9	1.0	0.8	0.3
Ever highly irritable/argumentative for 2 days	0.5	0.5	2.6	-0.9	0.5	0.8	1.1	0.6	1.1	0.2	0.4	0.2	-0.8	-0.2	-0.6	-1.6	-0.5	-0.3	-0.1
Medication for cholesterol, blood pressure or diabetes	0.5	0.9	3.3	0.3	-0.2	-0.1	-0.1	-1.8	-0.1	-1.6	-0.2	1.4	-1.0	-1.6	-0.7	-0.3	-1.2	-0.4	-0.3
Body fat percentage	0.5	2.0	5.9	-1.3	-0.9	0.2	0.3	-0.2	0.1	-1.5	-1.1	-2.4	-1.9	-2.1	-1.4	-1.8	-1.8	-1.5	-1.2
Mouth/teeth dental problems: Loose teeth	0.5	0.6	2.5	-0.6	-0.6	-1.1	-0.9	0.0	-0.8	1.0	-0.2	0.4	1.0	0.5	1.6	-1.1	0.4	0.4	-0.4
Medication for pain relief, constipation, heartburn	0.5	0.8	2.4	-0.2	-0.8	-1.1	-1.4	0.2	-1.6	0.9	0.0	1.1	1.2	0.6	1.2	0.2	0.9	0.6	0.2
Migraine (self-reported)	0.5	0.6	2.5	-0.4	0.8	1.3	1.1	0.4	1.1	-0.7	0.2	1.6	-0.4	0.0	-0.9	0.6	-0.2	-0.3	-0.3
Leg pain on walking	0.5	0.6	3.5	1.1	1.3	0.1	-0.2	0.3	-0.0	-1.0	1.9	0.0	-0.0	-0.2	-0.1	0.3	0.2	0.8	0.9
Illness, injury, bereavement, stress in last 2 years	0.5	0.7	3.8	-0.3	-0.4	0.7	0.9	0.4	0.7	-0.0	-1.0	2.0	-0.7	-0.6	-0.6	-0.2	-0.6	-1.0	-0.9
Loneliness, isolation	0.5	0.7	2.7	-0.1	-1.7	-0.6	-0.9	-0.5	-0.9	-0.9	-1.6	-1.0	0.2	-0.4	-0.1	0.8	-0.3	-0.7	-0.9
Ever had bowel cancer screening	0.5	0.6	3.4	0.1	-0.9	-0.4	-0.2	0.6	0.0	-0.4	-1.1	-1.1	0.8	0.8	0.6	0.3	0.6	-0.3	-1.8
Medication for cholesterol	0.5	0.7	2.3	-0.1	-1.5	-0.4	-0.6	-1.1	-0.2	0.3	-1.5	1.4	0.3	-0.1	0.6	0.8	-0.3	-0.7	-1.0
Hearing aid user	0.5	0.5	1.9	0.7	1.4	0.8	0.5	0.6	0.3	0.5	1.3	-0.1	-0.0	-0.2	-0.3	0.5	0.1	0.6	1.4
Medication: Atorvastatin	0.5	0.6	2.0	-1.0	1.1	0.6	1.0	1.4	0.7	0.7	0.9	-0.6	-0.2	0.8	-0.0	-1.0	0.2	0.2	0.9
Unable to work because of sickness or disability	0.5	0.6	2.5	1.6	0.1	-1.0	-0.9	0.4	-0.9	-0.1	0.8	-0.6	0.9	-0.0	0.8	0.8	0.6	1.2	0.3
Heart attack/myocardial infarction (self-reported)	0.5	0.6	4.8	0.7	0.7	0.2	0.1	0.7	0.1	1.3	0.3	2.2	0.3	0.7	0.2	0.5	0.6	0.5	0.8
Alzheimer’s Disease (in mother)	0.4	0.5	2.0	-0.7	-1.4	-0.8	-0.8	0.7	-1.1	-0.8	-0.6	-0.7	0.4	-0.2	0.6	0.2	0.0	-0.1	-0.7
Breast Cancer	0.4	1.0	2.9	1.4	-0.8	-1.5	-1.7	-0.9	-1.6	-0.5	-0.0	0.7	1.0	-0.2	1.3	1.2	0.5	0.7	-0.2
Crohns Disease (2012)	0.4	0.7	3.8	0.4	0.2	0.1	-0.7	0.4	-0.6	-0.1	0.7	1.9	1.1	0.5	0.5	1.3	1.0	0.8	0.2
Mean Putamen Volume	0.4	0.4	0.9	0.2	-0.1	0.7	0.8	-0.2	0.9	-0.1	-0.5	0.8	-0.7	-0.9	-0.9	-0.3	-0.8	-0.9	-0.5
Smoking Status	0.4	0.9	3.1	-1.0	-0.6	-0.7	-0.9	1.3	-0.8	-1.4	-0.4	-0.3	-0.4	-1.4	-0.2	-0.9	-1.0	-0.9	-1.8
Cardiovascular Disease	0.4	1.3	9.2	-0.8	0.7	0.1	0.6	3.0	0.7	1.3	0.6	-0.4	0.9	1.8	0.7	-0.7	1.2	0.8	0.9
Trunk fat percentage	0.4	1.4	5.6	-1.0	-0.7	0.1	0.1	-0.6	-0.1	-1.2	-0.8	-2.4	-1.6	-1.7	-1.1	-1.4	-1.4	-1.1	-1.1
Bilateral oophorectomy (both ovaries removed)	0.4	0.4	1.7	-0.2	-0.5	0.1	0.2	0.1	0.4	-0.4	-0.5	-1.3	-0.9	-0.9	-0.9	-0.5	-0.7	-0.7	-0.5
Stomach or abdominal pain in last month	0.4	0.5	2.0	-0.2	-0.2	0.4	0.5	-0.4	0.4	-1.3	-0.4	0.1	-1.0	-1.4	-1.0	-0.1	-1.1	-0.7	-0.2
Sitting height	0.4	3.0	8.8	1.4	-2.1	-2.6	-2.6	-2.6	-3.0	0.8	-1.0	-0.3	1.8	0.5	2.4	0.9	1.0	0.6	-0.6
Number of incorrect matches in round	0.4	0.7	2.4	0.3	-1.6	-1.3	-1.3	-0.4	-1.5	-0.6	-1.0	-0.4	-0.0	-0.9	0.5	-0.3	-0.3	-0.4	-0.7
Had other major operations	0.4	0.5	5.2	0.4	-0.5	-0.9	-0.6	-2.3	-0.7	-0.5	-0.4	-0.1	0.0	0.4	0.6	0.1	0.1	0.0	-0.4
Forced vital capacity (FVC)	0.4	1.6	4.0	1.7	0.7	-1.1	-1.1	-2.0	-0.9	1.2	1.2	0.6	1.1	1.2	1.4	0.9	1.4	1.6	1.3
Heel bone mineral density (BMD) T-score, automated (right)	0.4	0.9	2.3	1.0	-0.8	-1.0	-1.2	-0.3	-0.8	0.7	0.1	0.3	1.1	0.6	1.5	1.2	0.9	1.0	1.1
Fluid intelligence score	0.4	0.9	5.4	-1.8	0.5	-0.2	0.5	0.9	0.2	2.3	0.2	0.4	0.3	1.3	0.7	-1.1	0.4	0.3	0.8
Arm fat percentage (right)	0.4	1.5	3.8	-1.2	0.1	0.9	0.9	0.5	0.7	-1.0	-0.2	-1.9	-1.9	-1.5	-1.6	-1.8	-1.5	-1.1	-0.3
Qualifications: A levels/AS levels or equivalent	0.4	0.8	2.8	-1.7	0.5	1.2	1.6	1.4	0.8	0.3	-0.3	0.3	-0.6	-0.1	-1.1	-0.2	-0.9	-1.0	0.1
Medication: Cholesterol lowering	0.4	0.7	2.4	0.4	0.4	-0.1	-0.0	1.5	0.1	1.6	0.3	-0.5	0.8	1.5	0.6	0.6	1.0	0.5	0.6
Impedance of arm (left)	0.4	1.7	4.7	1.5	1.7	-0.2	-0.2	-0.1	-0.2	1.1	2.2	1.2	1.4	1.7	0.9	1.7	1.6	2.0	0.8
Arm fat mass (right)	0.4	1.6	5.3	-1.4	-0.6	0.5	0.5	0.3	0.3	-0.8	-0.8	-2.3	-1.8	-1.6	-1.4	-1.9	-1.6	-1.3	-0.4
Breastfed as a baby	0.4	0.5	2.8	-0.3	0.2	0.1	0.6	1.2	-0.1	0.6	0.2	-0.4	0.8	1.7	0.8	-0.1	1.0	0.4	-0.1
Medication: Paracetamol	0.4	0.7	1.5	-0.3	0.5	1.2	1.1	0.1	1.2	-0.7	-0.1	-0.2	-1.0	-1.2	-1.2	-0.1	-1.1	-0.8	-0.0
Medication: Allopurinol	0.4	0.5	4.0	-0.7	-0.7	-0.0	0.3	-0.2	0.6	0.3	-1.0	-2.0	-0.4	-0.1	-0.1	-0.6	-0.5	-0.8	-0.3
Whole body fat mass	0.4	1.7	6.4	-1.1	-1.2	-0.1	-0.0	-0.6	-0.2	-1.0	-1.2	-2.5	-1.6	-1.9	-1.0	-1.8	-1.6	-1.4	-0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.5	1.4	-0.4	-0.1	0.5	0.4	1.1	0.4	-1.2	-0.6	-0.4	-0.6	-0.4	-1.0	-0.1	-0.6	-0.8	-1.2
Handedness (chirality/laterality): Left-handed	0.4	0.4	1.3	0.8	-0.4	-0.9	-1.0	0.0	-0.5	0.1	0.3	0.6	0.8	0.1	1.2	0.3	0.7	0.8	0.5
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.4	2.1	-0.0	0.6	0.6	0.6	1.5	0.2	-0.5	0.5	0.5	0.4	0.9	-0.3	0.9	0.3	0.1	-0.6
Medication: Gliclazide	0.4	0.4	3.5	1.0	-0.4	-0.6	-0.7	-0.2	-0.2	-0.4	-0.1	-1.9	0.1	-0.7	-0.1	0.2	-0.3	0.0	-0.2
Arm fat mass (left)	0.4	1.7	5.8	-1.4	-0.6	0.5	0.5	0.2	0.3	-0.8	-0.9	-2.4	-1.8	-1.7	-1.3	-2.0	-1.6	-1.4	-0.5
Cholesterol lowering medication	0.4	0.6	2.8	1.4	0.9	-0.5	-0.2	-0.2	-0.6	0.3	1.2	-0.6	0.3	0.3	0.1	-0.2	0.6	1.0	1.7
Medication: Omeprazole (e.g. Zanprol)	0.4	0.4	1.6	0.0	1.0	-0.3	-0.1	0.3	-0.0	-0.1	1.3	-0.6	0.4	1.0	0.8	0.2	0.9	1.1	0.1
Basal cell carcinoma (self-reported)	0.4	0.5	2.7	-0.6	1.2	0.7	0.3	0.2	0.4	0.3	1.1	0.5	-0.7	-0.5	-0.8	-0.4	-0.3	0.3	1.6
Impedance of whole body	0.4	2.2	4.6	1.8	0.8	-1.2	-1.2	-0.4	-1.1	0.7	1.7	1.7	2.0	1.5	1.6	2.1	1.7	2.1	0.6
Alzheimer’s Disease (including proxy)	0.3	0.5	1.8	-0.6	-1.2	-1.1	-0.9	-0.1	-1.3	-0.3	-0.3	-0.6	0.3	-0.1	0.8	-0.1	0.0	0.0	-0.7
Coronary Artery Disease (CAD)	0.3	0.3	1.8	0.7	-0.3	0.3	-0.2	0.1	-0.4	-1.1	-0.1	0.7	0.4	-0.1	-0.1	1.3	0.6	0.2	0.0
Systolic Blood Pressure	0.3	1.3	3.8	1.5	0.6	-1.0	-0.2	0.6	-0.1	1.9	0.9	0.1	1.3	1.9	1.4	-0.6	1.4	1.4	0.4
Lung FVC	0.3	1.3	4.0	0.1	2.0	0.6	1.2	-0.5	1.2	1.2	1.9	-0.0	0.1	1.6	0.3	-0.9	1.0	1.1	1.6
Vitamin and mineral supplements	0.3	0.4	0.9	0.2	0.4	-0.5	-0.3	0.5	-0.4	0.6	0.8	0.4	0.8	0.9	0.7	-0.1	0.9	0.8	0.1
Supplements: Zinc	0.3	0.3	0.9	0.0	-0.2	-0.6	-0.4	0.7	-0.3	-0.8	0.0	0.5	0.9	0.5	0.9	0.2	0.8	0.5	-0.8
Diabetes (father)	0.3	0.4	1.9	-1.4	-0.8	-0.1	-0.1	0.2	-0.2	-0.4	-0.5	-0.7	-0.6	-0.5	-0.5	-0.6	-0.3	-0.5	-0.7
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.4	1.2	0.4	-0.7	-1.1	-1.0	-0.6	-1.0	-0.8	-0.1	-0.1	0.6	-0.6	0.7	0.3	0.0	0.3	-0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.6	3.3	-0.6	-1.8	-0.6	-0.9	-0.1	-0.5	-0.3	-1.5	-0.8	0.4	-0.5	0.7	0.5	-0.1	-0.4	-0.5
High blood pressure	0.3	0.8	4.0	-0.1	-1.0	-1.1	-0.6	1.6	-0.5	0.3	-0.8	-2.0	0.7	0.3	0.9	-0.8	0.5	0.2	-0.2
Trunk fat mass	0.3	1.3	6.2	-0.7	-0.9	-0.2	-0.2	-0.9	-0.4	-1.0	-0.8	-2.5	-1.3	-1.6	-0.7	-1.4	-1.3	-1.0	-0.8
Mouth/teeth dental problems	0.3	0.4	2.2	0.2	0.7	0.8	0.7	0.2	0.6	0.1	0.6	1.5	-0.2	0.9	-0.1	0.8	0.5	0.3	0.1
Allergy	0.3	0.7	2.6	1.6	-0.3	-1.0	-1.1	0.1	-1.0	0.8	0.4	0.2	1.1	0.4	0.7	0.8	0.9	0.8	0.9
Trunk fat-free mass	0.3	1.5	4.4	1.0	-1.4	-1.9	-2.1	-1.8	-2.1	0.5	-0.6	-1.0	0.8	0.0	1.7	-0.2	0.6	0.5	0.7
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.5	2.7	-0.3	-0.9	-0.8	-0.6	0.4	-0.8	-1.0	-0.9	-1.6	0.7	-0.1	0.5	-0.0	0.2	-0.2	-0.9
Happiness	0.3	0.3	0.7	-0.8	0.8	0.6	0.5	0.9	0.5	-0.8	0.5	-0.3	-0.5	-0.5	-0.9	-0.1	-0.3	-0.3	-0.6
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	1.1	2.4	1.5	0.3	-0.9	-0.7	-0.7	-0.5	1.0	0.8	0.6	1.2	1.3	1.3	1.2	1.6	1.3	1.0
Trunk predicted mass	0.3	1.6	4.4	1.0	-1.4	-1.9	-2.1	-1.9	-2.1	0.5	-0.6	-1.1	0.8	0.0	1.7	-0.2	0.6	0.5	0.8
Birth weight of first child	0.3	0.5	2.3	1.0	-0.3	0.3	0.5	-1.0	0.4	-0.9	-0.5	-1.5	-0.6	-0.5	-0.8	0.2	-0.5	-0.6	-0.7
Forced vital capacity (FVC), Best measure	0.3	1.0	2.1	1.4	0.4	-0.8	-0.7	-1.2	-0.4	1.0	0.9	0.4	1.0	1.2	1.3	0.6	1.4	1.3	0.9
Worry too long after embarrassment	0.3	0.5	2.5	0.7	0.0	-0.2	-0.6	-0.4	-0.5	-0.3	0.4	0.2	1.2	0.6	0.7	1.6	0.9	0.7	-0.0
Qualifications: College or University degree	0.3	1.0	7.1	-0.3	0.4	0.1	-0.2	-0.1	-0.5	1.4	0.5	2.7	0.9	1.1	0.7	1.1	1.1	0.7	0.7
Medication: Blood pressure	0.3	0.5	2.6	-0.0	-0.1	-0.2	-0.1	1.0	-0.2	0.8	-0.0	-1.6	0.7	1.1	0.7	-0.4	0.8	0.2	0.0
Medication: Seretide 50 evohaler	0.3	0.4	1.7	-0.4	1.1	0.0	0.0	-0.4	-0.2	0.1	1.3	-0.8	-0.1	0.5	0.4	-0.7	0.5	0.9	0.4
Hypertension (Self-reported)	0.3	0.8	2.5	0.4	-0.6	-1.2	-0.7	1.2	-0.7	0.3	-0.2	-1.6	1.3	0.9	1.4	-0.2	1.0	0.8	0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.3	1.8	0.7	-0.1	-0.2	-0.4	-0.3	-0.5	1.1	0.3	0.0	0.0	0.5	0.2	0.2	0.6	0.6	1.4
Osteoarthritis (self-reported)	0.3	0.4	1.3	0.2	0.7	-0.1	-0.4	0.2	-0.2	0.9	0.8	-0.5	0.5	1.1	0.4	0.6	1.1	1.0	0.3
Illnesses of father: None of the above (group 1)	0.3	0.4	1.8	-0.0	-1.3	-0.7	-0.6	-0.1	-0.6	-0.1	-1.2	-0.6	0.2	-0.3	0.2	-0.0	-0.0	-0.3	-0.6
Ever taken oral contraceptive pill	0.3	0.4	2.6	-1.4	-0.3	-0.1	-0.1	1.6	-0.2	0.1	-0.4	-0.6	0.2	0.4	0.5	0.4	0.3	0.0	-0.2
Commuting to job workplace: Public transport	0.3	0.3	1.5	-0.3	0.4	0.1	-0.2	0.4	-0.5	1.2	0.8	0.1	0.4	0.5	0.5	0.4	0.2	0.6	1.2
Irritability	0.3	0.5	1.2	-0.5	-0.6	0.5	0.6	0.6	0.6	-0.6	-0.9	-0.6	-0.6	-1.1	-1.0	0.2	-0.9	-1.0	-0.3
Supplements: Calcium	0.3	0.3	1.0	-0.7	-0.2	0.7	0.7	1.0	1.0	0.6	-0.6	-0.4	-0.2	0.6	-0.4	0.3	0.4	-0.3	-0.1
Heart disease (siblings)	0.3	0.4	1.1	-0.7	-1.1	-0.9	-0.7	0.0	-0.8	0.2	-0.8	-0.6	-0.3	0.0	0.5	-1.0	0.0	-0.2	-0.9
Alcohol drinker status: Previous	0.3	0.4	2.0	-0.5	0.3	-0.9	-0.7	-1.4	-0.5	-0.5	0.7	-0.6	0.1	0.1	0.7	-0.7	0.0	0.6	0.1
Major Depression (MDD)	0.2	0.2	1.3	1.0	-0.4	0.0	-0.2	-0.0	-0.1	-0.2	-0.3	0.5	0.3	0.4	-0.2	1.1	0.3	0.2	-0.3
Body Mass Index (BMI) (2010)	0.2	0.3	1.0	0.6	-0.2	0.6	0.6	-1.0	0.4	0.1	-0.4	0.9	-0.4	-0.2	-0.7	0.9	-0.3	-0.3	0.3
Ulcerative Colitis	0.2	0.3	0.6	0.6	-0.3	-0.2	-0.0	-0.7	-0.5	0.7	-0.2	0.5	0.5	0.7	0.7	0.8	0.7	0.5	0.7
Tanning	0.2	2.3	6.4	1.0	1.6	-0.7	-0.4	0.0	-0.3	2.5	1.8	0.6	1.7	2.5	1.8	0.4	2.0	2.0	1.2
Hand grip strength (left)	0.2	0.6	2.6	0.2	0.3	-0.1	-0.7	0.7	-0.2	1.5	0.4	1.6	0.8	0.4	0.7	0.7	0.6	0.5	0.5
Number of treatments/medications taken	0.2	0.4	1.0	1.0	0.4	0.0	0.3	0.5	0.3	0.6	0.3	-0.8	0.5	0.9	0.4	0.1	0.9	0.6	0.9
Hand grip strength (right)	0.2	0.5	1.7	0.3	0.3	-0.1	-0.6	0.1	-0.4	1.0	0.3	1.1	0.8	0.8	0.7	1.3	0.8	0.6	0.3
Relative age voice broke	0.2	0.3	1.6	0.1	-0.7	-0.3	-0.4	0.5	-0.5	-1.3	-0.8	-0.3	0.3	-0.1	0.2	0.3	-0.2	-0.5	-1.0
Taking other prescription medications	0.2	0.3	1.6	1.3	0.0	-0.7	-0.4	-0.1	-0.5	0.3	0.1	-0.4	0.5	0.9	0.7	0.2	0.7	0.6	-0.0
Age when periods started (menarche)	0.2	0.6	1.7	-0.3	-0.1	-0.2	0.2	-1.2	0.4	-0.5	-0.5	-0.3	-0.8	-1.2	-0.7	-1.2	-1.3	-0.8	-0.8
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	0.6	-0.1	0.7	0.6	0.4	0.6	0.4	-0.2	0.5	0.2	-0.4	-0.1	-0.8	-0.3	-0.3	-0.1	0.0
Qualifications: CSEs or equivalent	0.2	0.2	1.4	0.4	0.2	-0.1	-0.3	-0.2	-0.2	-1.2	0.3	-0.2	0.0	-0.7	-0.3	0.8	-0.5	0.1	0.4
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.4	1.4	0.4	1.1	0.5	0.5	0.2	0.7	-0.6	1.2	-0.4	0.4	0.5	-0.0	0.4	0.5	0.7	0.2
Financial difficulties in last 2 years	0.2	0.2	1.1	0.1	0.2	0.5	0.1	0.8	0.1	0.3	0.3	-0.5	-0.3	-0.3	-0.7	-0.5	-0.2	-0.1	1.1
Medication: Simvastatin	0.2	0.3	3.1	0.9	-0.3	-0.7	-0.4	0.0	-0.4	-0.0	-0.4	-1.8	0.0	-0.1	-0.4	-0.4	-0.0	-0.2	-0.0
Weight	0.2	1.1	6.3	-0.4	-1.0	-0.4	-0.6	-1.1	-0.7	-0.8	-0.8	-2.5	-1.1	-1.4	-0.3	-1.4	-1.0	-0.8	-0.2
Hip circumference	0.2	1.1	6.3	-0.4	-0.8	-0.1	-0.1	-0.9	-0.2	-1.2	-0.7	-2.5	-1.2	-1.5	-0.7	-0.9	-1.1	-0.8	-0.3
Alcohol intake versus 10 years previously	0.2	0.4	1.3	0.7	-0.4	-0.3	-0.4	-1.0	0.1	-0.8	0.1	-1.2	-0.8	-0.5	-0.5	-0.8	-0.6	-0.2	-0.1
Falls in the last year	0.2	0.3	0.8	-0.7	-0.9	-0.5	-0.4	0.8	-0.4	-0.2	-0.8	-0.8	0.2	-0.2	0.3	-0.5	-0.1	-0.5	-0.8
Mouth/teeth dental problems: Dentures	0.2	0.3	1.3	1.1	0.5	-0.7	-0.5	-0.2	-0.4	0.3	0.6	0.1	0.1	-0.1	0.2	-0.2	0.0	0.6	0.8
Pulse wave Arterial Stiffness index	0.2	0.3	0.9	-0.9	0.2	-0.5	-0.6	0.9	-0.8	0.2	0.5	-0.5	0.2	0.1	0.5	-0.2	0.2	0.5	0.2
Hair/balding pattern: Pattern 4	0.2	0.4	1.1	0.6	-0.1	0.8	0.9	-0.2	0.6	-0.2	-0.6	-1.1	-0.6	0.3	-0.7	-0.1	-0.0	-0.6	-1.0
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	0.9	-0.8	-0.7	-0.5	-0.1	0.5	-0.0	1.0	-0.5	-0.4	0.5	0.6	0.6	-0.2	-0.0	-0.0	0.5
Mouth/teeth dental problems: Bleeding gums	0.2	0.2	1.3	-0.5	0.1	0.2	-0.1	0.4	-0.1	0.5	0.6	-0.7	0.0	-0.6	-0.0	-0.0	-0.0	0.3	1.1
Arm fat-free mass (right)	0.2	1.2	3.8	-0.3	-1.8	-1.3	-1.4	-1.2	-1.4	0.1	-1.4	-2.0	-0.2	-0.9	0.8	-1.1	-0.4	-0.7	-0.3
Pulse wave peak to peak time	0.2	0.2	1.6	1.2	-0.1	0.2	0.3	-1.3	0.5	-0.0	-0.3	0.5	0.1	0.1	-0.2	0.2	0.0	-0.2	0.1
Eye problems/disorders: None of the above	0.2	0.3	0.8	-0.7	-0.9	-0.4	-0.1	0.1	-0.3	0.1	-0.9	-0.4	-0.3	-0.8	-0.1	-0.1	-0.6	-0.7	-0.7
Emphysema/chronic bronchitis	0.2	0.2	0.9	-0.6	0.3	0.1	0.3	0.5	0.3	0.1	0.3	0.7	0.5	0.5	0.5	-1.0	0.5	0.3	0.5
Neck or shoulder pain in last month	0.2	0.3	1.3	0.6	0.5	-0.2	0.2	-1.1	0.6	-0.6	0.1	-1.1	-0.3	0.1	-0.2	-0.7	-0.3	-0.0	0.3
Medication: Omeprazole	0.2	0.3	0.8	0.5	0.6	-0.5	-0.1	0.2	-0.1	0.1	0.9	0.2	0.4	0.8	0.7	0.2	0.7	0.9	0.5
Heart disease (mother)	0.2	0.2	0.5	-0.3	0.6	0.6	0.4	-0.7	0.6	0.1	0.3	0.5	-0.5	-0.6	-0.4	-0.5	-0.5	-0.1	0.7
Arm predicted mass (right)	0.2	1.2	4.2	-0.3	-1.8	-1.4	-1.4	-1.2	-1.5	0.1	-1.4	-2.0	-0.0	-0.7	0.9	-1.0	-0.3	-0.6	-0.4
Family relationship satisfaction	0.2	0.2	0.6	-0.8	0.7	0.6	0.2	0.7	0.3	0.6	0.6	-0.7	-0.3	0.5	0.0	0.1	0.2	0.1	-0.1
Knee pain experienced in last month	0.2	0.4	1.8	1.3	0.6	-0.2	-0.4	-0.7	-0.7	-0.5	0.7	-0.4	0.5	0.3	0.4	0.4	0.5	0.6	0.4
Whole body fat-free mass	0.2	0.9	2.7	0.3	-1.3	-1.2	-1.4	-1.6	-1.4	0.1	-0.9	-1.6	0.0	-0.4	0.9	-0.6	-0.1	-0.3	0.1
Friendships satisfaction	0.2	0.3	0.9	0.3	0.3	-0.3	-0.4	0.0	-0.5	0.4	0.4	-0.5	0.5	1.0	0.6	0.9	0.8	0.5	0.2
Qualifications: nursing, teaching	0.2	0.4	1.1	0.1	1.0	0.6	0.5	-0.5	0.6	0.6	0.8	0.1	0.5	1.1	0.4	-0.3	0.7	0.6	0.2
Number of self-reported non-cancer illnesses	0.2	0.3	2.1	-0.1	0.5	-0.1	0.2	-0.4	-0.0	-0.6	0.3	-1.4	-0.5	0.2	-0.2	-1.4	-0.1	0.1	-0.0
Medication: Paracetamol	0.2	0.4	1.4	1.1	0.7	0.1	-0.0	-0.7	0.1	0.1	0.7	0.0	0.6	0.0	0.1	1.0	0.4	0.7	1.2
Medication: Lisinopril	0.2	0.3	0.9	0.2	-0.2	0.0	0.1	-1.0	0.1	-0.9	-0.7	0.4	-0.4	-0.4	-0.4	-0.5	-0.6	-0.7	-0.8
Arm fat-free mass (left)	0.2	1.1	2.8	0.3	-1.7	-1.4	-1.6	-1.4	-1.6	0.2	-1.2	-1.5	0.2	-0.5	1.0	-0.5	-0.1	-0.3	0.0
Vascular/heart problems diagnosed by doctor	0.2	0.5	4.0	0.2	0.0	0.2	-0.2	-2.0	-0.1	-0.3	0.1	1.2	-0.3	-0.5	-0.3	0.8	-0.4	-0.2	-0.0
Arm predicted mass (left)	0.2	1.2	3.5	0.2	-1.9	-1.5	-1.6	-1.5	-1.7	0.2	-1.4	-1.6	0.1	-0.6	1.0	-0.6	-0.1	-0.4	0.1
Intelligence (Savage-Jansen 2018)	0.1	0.3	1.0	-0.9	0.8	0.3	0.7	0.8	0.3	0.5	1.0	-0.6	0.2	0.7	0.1	-0.2	0.5	0.4	-0.4
Verbal and Numeric Reasoning (VNR)	0.1	0.3	2.5	-1.6	-0.5	-0.6	-0.2	0.4	-0.6	0.6	-0.2	-0.3	0.1	-0.1	0.4	-0.9	-0.3	-0.2	-0.5
Prostate Cancer	0.1	0.1	0.5	0.1	0.4	0.1	0.4	-0.4	0.0	-0.2	0.4	0.7	-0.0	-0.0	-0.2	-0.3	-0.1	0.2	0.6
Blood Eosinophil Count	0.1	0.5	2.2	0.5	1.2	0.4	0.2	0.5	0.1	-0.2	1.5	0.8	0.5	0.7	0.4	0.8	0.5	0.9	-0.2
Heel T-Score	0.1	0.8	2.9	-1.4	-1.2	-0.6	-0.3	1.7	-0.5	-0.7	-1.0	-0.9	0.7	0.9	1.1	-0.5	0.6	0.0	-0.8
Systolic blood pressure, automated reading	0.1	0.3	1.8	0.7	-0.4	-1.0	-0.2	0.3	-0.4	0.3	-0.0	-0.9	0.4	0.3	0.5	-1.4	0.1	0.3	-0.3
Leg fat-free mass (left)	0.1	0.6	3.5	-0.3	-0.8	-0.1	-0.3	-1.2	-0.3	-0.1	-0.9	-1.9	-0.7	-0.8	-0.1	-0.7	-0.6	-0.8	-0.4
Leg predicted mass (left)	0.1	0.6	3.5	-0.4	-0.8	0.0	-0.2	-1.0	-0.3	-0.1	-1.0	-1.9	-0.8	-0.8	-0.1	-0.7	-0.6	-0.9	-0.4
Past tobacco smoking	0.1	0.3	1.1	0.3	-0.2	0.6	0.5	-1.0	0.6	-0.9	-0.5	0.1	-0.4	-0.5	-0.6	0.5	-0.2	-0.3	-0.0
Qualifications: None of the above	0.1	0.3	1.1	1.0	-0.2	-0.2	-0.4	-0.9	-0.6	-0.9	0.1	-0.5	-0.3	-1.1	-0.4	0.1	-0.5	-0.1	0.3
Exposure to tobacco smoke at home	0.1	0.1	0.5	-0.4	-0.3	-0.3	0.1	0.7	0.1	0.1	-0.4	0.1	0.2	0.3	0.1	-0.0	-0.0	-0.1	-0.4
Peak expiratory flow (PEF)	0.1	0.3	1.0	0.4	0.6	-0.7	-0.1	-0.1	0.1	0.5	1.0	-0.2	0.5	0.9	0.8	-0.5	0.7	0.9	0.3
Smoking status: Previous	0.1	0.2	0.5	-0.2	0.7	0.5	0.5	0.3	0.2	0.6	0.5	0.5	-0.3	0.0	-0.4	-0.1	-0.3	-0.2	0.3
Leg fat-free mass (right)	0.1	0.5	3.2	-0.6	-0.4	0.5	0.1	-0.9	0.1	0.0	-0.7	-1.8	-0.9	-0.7	-0.4	-0.8	-0.6	-0.9	-0.3
Whole body water mass	0.1	0.8	2.2	0.3	-1.2	-1.1	-1.4	-1.5	-1.4	0.2	-0.8	-1.4	0.1	-0.3	0.9	-0.4	0.0	-0.1	0.2
Leg predicted mass (right)	0.1	0.5	3.3	-0.5	-0.3	0.5	0.1	-0.9	0.2	0.0	-0.6	-1.8	-1.0	-0.6	-0.4	-0.8	-0.6	-0.8	-0.2
Basal metabolic rate	0.1	0.8	2.7	0.2	-1.3	-1.1	-1.3	-1.4	-1.3	0.1	-0.9	-1.6	-0.1	-0.6	0.7	-0.5	-0.2	-0.3	0.2
Ever had prostate specific antigen (PSA) test	0.1	0.1	0.7	-0.5	-0.1	-0.1	0.3	0.6	-0.2	0.5	-0.2	-0.0	-0.0	0.8	0.3	-0.6	0.3	0.1	-0.3
Age started oral contraceptive pill	0.1	0.2	0.6	0.1	0.7	0.5	0.5	0.0	0.1	0.3	0.7	-0.8	0.2	0.4	0.1	0.0	0.4	0.4	0.2
Hair Pigment	0.0	1.1	2.4	-0.3	1.5	1.5	0.8	1.6	0.9	0.6	1.4	0.9	0.3	1.4	-0.5	1.1	1.0	0.6	1.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.0	0.1	0.2	0.3	-0.5	-0.3	-0.1	-0.4	0.2	-0.5	-0.4	-0.1	0.1	-0.5	-0.2	-0.3	-0.1	-0.3	-0.3

Hub : Genes

ESYT2

Models

Trait associations