Hub : Genes

FAM129A

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Coronary	0.1680	0.0700	7.5e-03	0.033	NA	0.077	NA	0.024	2.8e-02	NA	1.4e-03	NA	5.3e-02
2	GTEx	Cells Transformed fibroblasts	0.1350	0.0490	1.7e-03	0.032	NA	0.080	NA	0.069	1.7e-03	NA	1.3e-06	NA	6.8e-06
3	GTEx	Colon Sigmoid	0.2120	0.0790	7.4e-04	0.063	NA	0.011	NA	0.037	3.0e-03	NA	1.3e-01	NA	1.8e-02
4	GTEx	Esophagus Muscularis	0.0730	0.0320	5.8e-03	0.108	NA	0.071	NA	0.003	4.3e-07	NA	4.1e-05	NA	1.9e-01
5	GTEx	Nerve Tibial	0.1154	0.0372	2.9e-05	0.055	NA	0.100	NA	0.092	9.6e-05	NA	1.5e-07	NA	4.7e-07
6	YFS	Blood	0.0593	0.0162	0.0e+00	0.055	0.058	0.062	0.058	0.064	1.4e-17	2.4e-18	2.1e-19	1.7e-18	5.7e-20
7	TCGA	Kidney Renal Clear Cell Carcinoma	0.0731	0.0328	6.1e-04	0.025	0.018	0.016	NA	0.016	6.6e-04	3.7e-03	6.0e-03	NA	5.2e-03
8	TCGA	Kidney Renal Papillary Cell Carcinoma	0.2000	0.0750	1.5e-05	0.014	0.050	0.059	NA	0.042	5.3e-02	7.3e-04	2.9e-04	NA	2.0e-03
9	TCGA	Prostate Adenocarcinoma	0.1025	0.0407	3.9e-06	0.043	0.046	0.050	NA	-0.002	2.3e-05	1.3e-05	6.2e-06	NA	7.2e-01

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	1.0	1.6	4.0	-0.2	-1.9	2.0	1.8	0.6	-0.2	-1.0	0.2	-1.6
Bipolar Disorder or Schizophrenia	0.9	2.2	6.6	-0.5	-2.6	1.3	1.7	0.3	-0.9	-1.6	-1.9	-1.1
Depressed Affect (Nagel 2018)	1.3	2.8	7.7	-1.9	1.4	-0.9	-1.6	-1.9	2.8	2.1	-0.2	0.5
Depression (Nagel 2018)	0.6	0.9	4.2	-2.0	0.1	-0.4	-0.7	-0.8	1.2	0.9	-0.1	0.9
Intelligence (Savage-Jansen 2018)	2.0	6.2	16.2	0.7	-0.7	2.9	2.9	3.0	-4.0	-3.2	0.8	-1.5
Neuroticism (Nagel 2018)	0.7	1.6	3.5	-1.2	0.2	-1.1	-1.2	-1.8	1.9	0.8	-1.2	1.0
Schizophrenia (2018)	0.7	1.5	7.2	-0.5	-1.8	0.0	0.8	0.0	-1.0	-1.2	-2.7	0.1
Schizophrenia vs Biploar Disorder	0.3	0.4	1.2	0.3	0.4	-0.8	-0.3	-0.9	0.2	-1.1	-0.6	0.3
Worry (Nagel 2018)	0.1	0.2	0.9	0.2	-0.6	-0.2	0.1	-0.5	0.1	-0.4	-1.0	-0.1
Alzheimer’s Disease (in mother)	1.6	1.9	3.7	1.0	0.6	1.9	1.4	1.9	-1.9	-0.9	1.2	-0.5
Alzheimer’s Disease (in father)	0.9	1.0	2.4	-0.5	-0.6	-0.8	-0.5	-1.3	1.6	0.5	-1.5	0.7
Alzheimer’s Disease (including proxy)	0.3	0.4	1.2	1.0	0.0	1.1	1.0	0.4	0.1	0.0	0.1	-0.0
Crohns Disease (2017)	0.8	1.7	4.6	0.7	1.9	0.6	1.1	1.4	-0.5	1.6	2.1	-0.3
Irritable Bowel Disease (IBD)	0.2	0.4	1.8	-0.5	1.4	-0.2	0.5	0.3	0.2	1.1	0.2	-0.2
Ulcerative Colitis (UC)	0.5	0.9	3.6	-0.8	0.9	-1.2	-0.4	-0.8	0.5	0.4	-1.9	0.5
Major Depression (MDD)	1.2	1.4	3.5	-1.4	-0.3	-1.2	-1.2	-1.6	1.9	0.8	-0.8	0.7
Reaction Time	0.1	0.2	1.4	0.0	0.5	-0.4	-0.4	-0.0	0.1	1.2	-0.2	-0.4
Verbal and Numeric Reasoning (VNR)	2.5	6.1	13.0	1.4	0.5	3.2	3.2	3.2	-3.6	-1.0	1.7	-2.2
Breast Cancer	0.1	0.3	0.8	0.0	-0.3	0.2	-0.5	-0.7	0.9	-0.6	0.1	-0.9
Ovarian Cancer	0.8	1.0	2.2	1.1	-0.7	1.1	1.0	1.0	-1.5	-1.3	0.1	-0.2
Prostate Cancer	0.2	0.3	1.0	-0.8	-1.0	-0.1	-0.3	-0.2	0.1	-0.6	-0.3	0.9
Age at First Birth	0.6	0.8	3.0	1.0	1.1	0.1	0.7	0.9	-1.7	-0.7	-0.2	-0.6
Bipolar Disorder (2011)	2.6	2.6	4.6	2.0	-1.0	2.2	2.0	1.7	-1.3	-0.0	0.9	-1.9
Body Mass Index (BMI) (2010)	1.9	2.6	5.6	-2.4	-0.2	-1.8	-1.8	-1.8	2.1	0.9	-0.7	1.4
Coronary Artery Disease (CAD)	1.6	1.9	3.2	-1.5	1.0	-1.4	-1.6	-1.5	0.9	-0.2	-1.7	1.8
Crohns Disease (2012)	1.6	2.5	4.6	1.7	1.6	1.4	1.8	2.1	-1.4	0.8	2.1	-0.6
Mean Putamen Volume	0.4	0.5	1.1	0.1	1.1	-0.2	-0.6	-0.5	0.8	1.0	0.7	0.5
Fasting Glucose	0.4	0.4	2.2	-0.4	-1.5	-0.2	-0.1	-0.6	0.9	-0.1	0.6	-0.2
HbA1C	0.6	0.7	2.3	0.7	-0.2	0.9	0.7	0.2	1.0	-0.4	1.5	-1.0
HDL Cholesterol	1.0	1.6	3.4	0.7	0.2	1.9	1.7	1.7	-1.2	0.9	1.0	-1.4
LDL Cholesterol	0.7	1.0	2.2	1.1	-1.3	1.1	1.5	0.7	-0.4	0.0	0.6	-1.4
Lupus	2.0	3.1	7.7	-1.9	1.6	-1.7	-2.8	-1.9	2.0	1.3	0.1	1.4
Neuroticism (2016)	0.7	1.1	3.2	-0.3	-1.0	1.2	1.1	0.6	-1.0	-1.8	-0.7	-0.9
Primary Biliary Cirrhosis	0.4	0.6	1.8	-0.8	-0.0	-0.3	-0.8	-1.2	1.4	0.4	-0.6	0.8
Rheumatoid Arthritis	0.5	0.6	2.0	0.7	-1.4	0.1	0.2	-0.8	0.5	-1.1	-0.9	0.4
Schizophrenia (2014)	0.8	1.8	4.4	-1.1	-2.0	0.4	1.0	0.0	-1.3	-2.1	-2.0	0.1
Triglycerides	0.2	0.3	0.6	-0.3	-0.7	-0.7	-0.5	-0.1	-0.5	-0.5	-0.7	0.3
Type 2 Diabetes (T2D) (2012)	0.5	0.6	1.7	-1.3	0.3	-0.4	-0.2	-1.0	0.8	-0.2	-1.1	0.3
Ulcerative Colitis	0.1	0.2	1.2	0.1	0.6	-0.2	0.3	-0.3	0.0	-0.1	-1.1	-0.4
Blood Eosinophil Count	0.3	2.6	8.0	-1.3	-2.8	0.1	0.2	-0.5	-0.5	-2.5	-2.1	-1.6
Blood Platelet Count	1.8	21.1	45.7	-4.9	2.0	-4.5	-5.1	-4.9	6.8	6.2	-1.7	2.0
Blood Red Count	0.2	1.8	4.5	-0.2	-0.7	1.6	1.6	1.1	0.2	1.1	2.0	-2.1
Blood White Count	0.8	5.9	12.3	-3.5	-0.5	-2.6	-2.9	-2.6	3.1	2.3	-1.7	1.0
Heel T-Score	0.5	3.9	9.8	-1.1	-0.1	-2.0	-2.0	-2.2	0.6	-2.7	-3.1	1.8
BMI	0.6	3.7	11.8	-1.2	-0.7	-1.1	-2.0	-1.9	3.4	3.3	-0.1	0.5
Height	1.0	19.9	35.3	5.2	3.7	4.4	4.3	5.9	-5.5	1.1	5.5	-2.1
Waist Hip Ratio (WHR)	0.3	1.3	3.0	-1.0	0.6	0.9	1.7	1.3	-0.7	1.2	0.3	-1.7
Systolic Blood Pressure	1.4	6.9	14.3	-2.6	-1.5	-3.1	-3.4	-3.5	3.8	0.9	-1.5	1.4
Smoking Status	0.3	0.6	2.7	0.1	1.6	0.4	-0.5	0.5	-0.4	0.8	1.2	0.3
Allergy or Eczema	0.7	1.9	3.8	1.9	1.1	1.4	0.8	1.0	-1.3	-0.9	1.7	-1.7
Cardiovascular Disease	0.7	2.2	6.2	-0.8	-2.4	-1.1	-1.4	-1.7	2.5	1.0	0.0	0.1
Hypothyroidism (self reported)	0.8	1.9	11.8	0.3	3.4	0.7	0.0	0.4	-0.0	1.3	1.6	0.7
Respiratory disease	0.2	0.5	2.3	0.8	0.1	1.0	0.7	0.4	-0.4	-0.3	0.2	-1.5
Type 2 Diabetes (T2D) (2018)	0.8	1.6	6.8	-0.7	-0.8	-0.2	-0.8	-1.2	2.6	1.8	0.9	-0.3
Lung FEV1/FVC ratio	0.6	2.9	9.1	1.2	0.6	1.3	2.0	2.3	-3.0	-1.9	-0.5	-0.3
Lung FVC	0.4	1.9	4.4	2.1	1.4	1.3	1.1	1.8	-1.9	0.7	0.7	-0.2
Neuroticism	0.4	0.9	2.3	-1.1	0.4	-0.4	-0.8	-1.2	1.5	1.2	-0.8	0.0
Chronotype (morning person)	0.3	0.8	1.7	-1.0	1.0	-0.8	-1.0	-0.3	-0.2	-0.7	-0.9	1.3
Hair Pigment	0.1	1.7	5.5	-1.9	-2.4	-1.5	-0.6	-0.6	0.2	0.1	-1.1	1.3
Tanning	0.0	0.2	0.5	0.3	-0.7	0.0	-0.2	-0.3	0.3	-0.5	-0.7	0.2
Hand grip strength (left)	1.9	5.1	9.8	3.1	0.3	2.3	2.5	2.7	-3.0	-2.1	1.7	-1.0
Number of treatments/medications taken	0.6	1.0	2.3	-0.4	0.1	-0.8	-1.2	-1.2	1.5	1.5	-0.6	0.5
Average weekly spirits intake	2.0	2.5	6.0	0.1	-2.4	1.8	1.8	1.3	-1.5	-1.7	-0.1	-1.8
Sensitivity / hurt feelings	1.1	1.8	3.9	-1.7	-1.8	-1.0	-1.1	-1.5	1.4	-0.2	-2.0	0.1
Frequency of depressed mood in last 2 weeks	0.5	0.7	2.2	-1.5	-0.0	-0.6	-1.1	-0.7	1.0	0.7	0.4	0.9
Hearing difficulty/problems: Yes	0.5	0.7	2.7	-1.2	1.6	-0.6	-0.4	-0.8	0.5	-0.6	-0.5	0.5
Relative age of first facial hair	0.4	0.9	1.4	-0.4	-1.1	1.2	1.1	0.7	0.2	1.0	1.1	-1.1
Other serious medical condition/disability diagnosed by doctor	0.6	0.7	4.2	0.9	2.1	-0.4	0.1	-0.2	0.3	0.9	0.2	0.6
Ever used hormone-replacement therapy (HRT)	1.0	1.3	3.2	-1.7	0.2	-0.4	-1.2	-0.5	1.8	1.7	0.8	0.6
Ever had hysterectomy (womb removed)	0.7	0.8	2.1	-0.5	1.3	-1.1	-0.9	-0.1	0.6	1.4	0.1	1.0
Systolic blood pressure, automated reading	3.1	8.9	21.5	-2.9	-1.3	-3.4	-3.7	-4.0	4.6	1.2	-1.1	2.2
Eye problems/disorders: Diabetes related eye disease	0.8	0.9	2.6	0.9	-1.6	1.1	0.7	0.4	0.3	0.1	1.1	-1.1
Angina	1.8	2.4	4.4	-2.1	-1.2	-2.0	-1.7	-1.7	1.0	-0.9	-1.4	1.6
Medication for hormone replacement therapy	2.2	2.5	5.2	-0.3	-0.0	-2.3	-2.2	-1.9	2.1	1.2	-0.5	1.7
Vitamin and mineral supplements	0.3	0.4	1.1	-0.5	1.0	-0.0	-0.7	-0.2	0.3	0.2	1.0	0.7
Supplements: Zinc	0.3	0.3	1.7	-0.1	0.1	-0.5	-0.2	-0.3	-0.3	-0.5	-1.3	0.4
Medication: Co-codamol	0.7	0.9	2.6	1.2	0.6	0.5	1.0	1.4	-1.6	0.4	-0.0	0.3
Medication: Metformin	1.6	2.3	9.2	-0.4	0.0	-1.2	-1.6	-1.8	3.0	1.8	0.4	0.8
Diabetes (father)	0.4	0.5	1.4	-1.2	-0.7	-0.6	-0.9	-0.5	0.6	1.0	-0.2	0.2
Diabetes (mother)	0.4	0.5	1.8	0.5	-1.1	0.1	-0.5	-1.0	1.3	-0.2	-0.1	-0.3
Severe depression (siblings)	0.5	0.6	1.9	-0.1	-0.2	0.4	0.6	1.1	-1.2	0.6	-1.4	-0.2
Pack years adult smoking proportion	0.5	0.8	2.2	-0.7	0.4	-1.0	-1.2	-0.6	0.6	1.5	-0.5	0.7
Impedance of leg (right)	0.5	2.4	4.3	-1.6	-1.7	-1.8	-1.5	-2.1	2.1	-0.2	-1.3	0.9
Leg fat-free mass (left)	0.4	2.4	5.3	2.3	1.3	1.7	1.1	1.3	-0.6	1.4	2.1	-1.2
Trunk fat percentage	1.5	6.1	18.2	-1.9	0.3	-2.0	-3.3	-3.0	4.3	2.6	0.3	1.7
Hand grip strength (right)	1.2	3.4	7.6	1.9	0.3	1.9	2.2	2.2	-2.8	-1.6	1.1	-1.2
Townsend deprivation index at recruitment	1.1	1.5	3.3	-1.6	-1.3	-0.5	-1.4	-1.8	1.8	-0.3	-0.3	0.7
Current tobacco smoking	0.3	0.4	1.6	0.3	0.5	-0.4	-0.8	-0.8	1.3	0.6	-0.3	0.3
Average weekly fortified wine intake	0.5	0.6	2.2	-1.3	-0.3	-0.2	-0.7	-0.1	0.6	1.5	0.9	-0.1
Maternal smoking around birth	1.8	2.7	5.2	0.0	0.9	-1.9	-2.1	-1.9	1.8	1.2	-1.2	2.3
Fed-up feelings	1.0	1.7	6.0	-0.9	1.0	0.6	-0.3	-0.6	2.1	2.5	0.7	-1.3
Frequency of unenthusiasm / disinterest in last 2 weeks	1.1	1.5	3.7	-1.9	-0.6	-0.6	-1.1	-1.2	1.9	1.2	0.2	1.1
Relative age voice broke	1.0	1.6	9.0	-0.7	-3.0	1.0	0.8	0.0	0.9	0.5	0.3	-1.4
Taking other prescription medications	1.0	1.5	6.5	1.8	2.5	-0.6	-0.6	-0.0	0.4	1.8	0.2	0.4
Age when periods started (menarche)	0.1	0.3	0.8	0.2	-0.6	0.4	0.7	-0.4	0.1	-0.8	0.3	-0.9
Bilateral oophorectomy (both ovaries removed)	2.3	2.7	5.6	-1.2	1.7	-2.2	-2.2	-1.5	1.5	0.7	-0.3	2.4
Heel bone mineral density (BMD) T-score, automated (left)	0.8	1.8	5.5	-0.4	0.1	-1.0	-1.6	-1.4	2.1	2.3	-0.1	0.7
Tinnitus: Yes, but not now, but have in the past	1.8	1.9	4.8	-2.2	-1.4	-1.6	-1.6	-1.2	0.7	-0.5	-1.4	1.1
Qualifications: CSEs or equivalent	1.6	2.1	6.1	-0.9	-0.2	-1.4	-1.6	-2.0	2.5	1.4	-1.1	0.5
Serious illness, injury or assault to yourself	0.9	1.1	4.0	-0.8	1.0	-1.1	-0.9	-1.0	0.7	0.3	-2.0	0.7
High blood pressure	1.4	4.0	9.6	-3.0	-2.7	-1.1	-1.7	-2.3	3.1	0.8	0.0	0.6
Hayfever, allergic rhinitis or eczema	0.7	1.5	3.9	2.0	0.4	1.1	0.8	0.9	-1.2	-0.9	1.5	-1.5
Multivitamins +/- minerals	0.4	0.5	1.2	-1.1	-1.0	-0.5	0.0	-0.3	-0.0	-0.6	-1.0	0.7
Stomach or abdominal pain in last month	4.0	4.9	7.7	-2.0	1.9	-2.7	-2.8	-2.4	2.8	2.3	-0.9	1.6
Supplements: Glucosamine	0.4	0.5	1.5	0.3	0.8	0.3	0.7	0.7	-1.2	-0.5	0.5	0.9
Diverticular disease/diverticulitis (self-reported)	0.2	0.3	0.9	0.3	-0.2	0.2	0.3	0.4	-0.9	-0.9	0.2	0.5
Medication: Atenolol	0.3	0.4	2.1	-0.6	-0.6	-0.1	0.3	-0.1	-0.7	-1.4	-0.7	0.3
Medication: Levothyroxine sodium	0.6	1.0	4.8	-0.3	2.2	0.4	-0.2	0.1	0.4	1.1	1.1	1.1
Sitting height	0.8	5.6	13.1	3.1	1.6	2.7	1.8	2.7	-1.9	1.4	3.6	-1.3
Chronic bronchitis/emphysema (father)	0.3	0.3	0.7	0.1	-0.2	-0.6	-0.8	-0.8	0.8	-0.6	-0.2	0.3
High blood pressure (mother)	0.3	0.4	1.6	-0.5	-1.2	-0.2	-0.6	-0.3	0.3	-0.3	0.6	0.5
Body mass index (BMI)	1.1	4.5	13.1	-1.4	-0.1	-1.8	-2.9	-2.6	3.6	2.4	-0.3	1.2
Impedance of leg (left)	0.5	2.3	3.5	-1.9	-1.5	-1.7	-1.7	-1.9	1.8	-0.1	-1.0	1.3
Leg predicted mass (left)	0.4	2.2	4.9	2.2	1.3	1.6	1.1	1.2	-0.5	1.3	2.1	-1.1
Trunk fat mass	0.8	3.5	10.8	-0.8	0.5	-1.1	-2.3	-2.0	3.3	2.6	0.9	1.0
Waist circumference	0.4	1.5	6.5	-1.1	0.6	-0.0	-0.9	-0.6	1.8	2.5	1.0	-0.3
Number of incorrect matches in round	0.2	0.4	1.0	1.0	-0.2	-0.1	-0.5	-0.6	1.0	0.1	0.1	0.8
Past tobacco smoking	0.2	0.4	2.2	-0.2	-0.7	-0.3	0.4	-0.1	-0.2	-0.4	-1.5	-0.1
Alcohol usually taken with meals	1.2	1.9	4.6	-1.7	-1.1	-1.1	-1.2	-1.9	2.1	-0.4	-1.0	1.0
Nervous feelings	0.2	0.4	1.1	1.1	-0.2	0.6	1.0	0.5	-0.4	-0.1	-0.5	-0.6
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.2	0.4	-0.5	0.5	0.3	-0.1	-0.3	0.5	0.0	0.6	0.4
Hearing difficulty/problems with background noise	0.2	0.3	1.0	-0.8	0.2	0.7	0.1	-0.1	0.6	-0.2	1.0	-0.0
Hair/balding pattern: Pattern 2	1.6	2.0	8.8	0.1	3.0	0.3	0.1	0.9	-0.4	2.0	2.0	-0.1
Had menopause	0.4	0.5	1.7	-0.1	-0.4	0.9	0.4	0.4	0.7	0.8	1.3	0.0
Had other major operations	0.1	0.1	0.6	-0.2	0.3	0.2	0.1	-0.1	0.6	0.3	-0.7	-0.1
Forced vital capacity (FVC)	1.7	6.5	12.5	2.8	0.1	3.5	2.9	3.0	-2.6	0.1	2.5	-2.8
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.6	1.8	-0.2	0.4	-0.6	-0.8	-1.0	1.2	1.4	-0.2	0.2
Ever unenthusiastic/disinterested for a whole week	1.2	1.4	4.5	-0.6	-0.8	-0.8	-0.7	-2.1	2.0	0.1	-1.0	0.9
Qualifications: None of the above	1.1	2.4	4.5	-0.5	-1.2	-2.1	-2.0	-2.1	2.1	0.0	-0.7	1.4
Financial difficulties in last 2 years	0.6	0.8	4.1	-0.4	-2.0	0.9	0.5	0.3	0.0	-0.1	-0.3	-1.3
Mouth/teeth dental problems	1.1	1.6	3.8	1.2	0.6	1.3	1.7	1.9	-1.6	0.9	1.0	-0.3
Heart attack	2.3	2.9	8.4	-1.1	-0.4	-2.1	-1.7	-1.6	0.2	-1.8	-2.9	1.9
Allergy	0.4	0.9	2.6	-1.5	0.4	-1.0	-0.6	-0.3	0.4	0.9	-0.8	1.6
Pain all over the body in last month	1.2	1.3	3.3	-0.8	0.3	-1.8	-1.5	-1.3	0.9	-0.2	-1.3	1.2
Diabetes (self-reported)	0.8	1.3	4.4	-0.4	-0.9	-0.4	-0.7	-0.9	2.1	1.9	1.2	-0.1
Hayfever/allergic rhinitis (self-reported)	0.8	1.1	1.9	1.3	1.4	-1.1	-1.3	-0.9	0.7	0.1	1.2	0.9
Medication: Ramipril	1.2	1.5	2.9	-1.5	-0.2	-1.4	-1.7	-1.4	1.5	0.4	0.1	1.3
Medication: Simvastatin	1.7	2.5	6.3	-1.7	-2.5	-1.5	-1.2	-1.6	1.5	-0.4	-1.8	0.8
Fluid intelligence score	2.3	4.8	8.8	1.6	1.0	3.0	2.7	2.6	-2.7	-0.7	2.2	-2.0
Illnesses of siblings	0.5	0.7	2.6	1.6	0.8	0.4	0.2	-0.1	0.5	0.4	1.4	-0.6
Neuroticism score	0.2	0.5	1.1	-1.0	-0.0	-0.1	-0.3	-0.6	1.0	1.0	-0.8	-0.5
Weight	0.3	1.7	7.2	1.0	0.8	0.5	-0.7	-0.3	1.6	2.7	1.7	-0.3
Impedance of arm (right)	0.1	0.4	1.8	-0.3	-0.0	-0.0	0.2	0.5	-1.0	-1.4	0.5	0.3
Arm fat percentage (right)	0.9	3.7	10.9	-1.3	-0.1	-1.6	-2.8	-2.3	3.3	1.8	-0.1	1.2
Trunk fat-free mass	1.0	5.8	11.2	3.4	0.9	2.8	2.6	2.9	-2.2	1.1	2.7	-2.1
Hip circumference	0.5	2.2	7.6	-0.1	1.3	-0.4	-1.6	-0.8	2.0	2.8	1.8	0.3
Time employed in main current job	0.9	1.0	3.2	1.2	0.8	0.4	0.9	1.6	-1.8	0.3	0.2	0.2
Alcohol intake versus 10 years previously	2.4	3.6	10.2	-1.1	-0.2	-2.2	-3.2	-2.4	2.8	0.9	-1.0	0.9
Father’s age at death	1.1	1.4	6.0	0.9	0.2	1.3	1.1	1.3	-0.9	-0.7	2.4	0.5
Worrier / anxious feelings	0.4	0.7	1.8	0.9	-0.5	0.2	0.8	0.6	-1.4	-1.1	-1.2	-0.2
Frequency of tiredness / lethargy in last 2 weeks	1.0	1.7	5.8	-1.0	-0.6	-0.2	-0.8	-1.1	2.4	2.3	0.4	0.7
Falls in the last year	1.1	1.5	3.9	-0.3	1.1	-1.6	-1.3	-1.5	0.8	-0.4	-2.0	1.2
Hair/balding pattern: Pattern 3	0.6	0.9	1.8	-0.4	0.0	-1.2	-1.4	-0.9	1.1	0.7	-0.7	1.1
Number of live births	1.4	2.0	6.9	0.8	0.4	1.4	1.4	1.7	-1.1	1.5	2.6	-0.6
Forced expiratory volume in 1-second (FEV1)	1.5	4.9	9.0	2.6	0.3	3.0	2.6	2.6	-2.4	-0.2	1.8	-2.4
Pulse rate	0.3	0.5	2.3	-0.1	0.8	0.1	0.0	0.8	-0.1	1.5	0.1	-1.0
Happiness	0.3	0.4	0.8	-0.2	-0.8	-0.3	-0.5	-0.9	0.8	0.4	-0.5	0.8
Noisy workplace	2.7	3.3	6.0	-2.1	1.2	-2.3	-2.4	-1.6	1.7	0.8	-2.3	1.2
Qualifications: A levels/AS levels or equivalent	1.3	2.8	9.4	1.0	1.9	0.8	1.4	2.6	-3.1	1.0	0.9	-0.1
Serious illness, injury or assault of a close relative in last 2 years	0.7	0.8	1.6	0.9	0.2	1.2	1.3	1.1	-1.0	0.1	0.7	-0.5
Mouth/teeth dental problems: Dentures	2.8	4.7	7.9	-2.3	-1.3	-2.1	-2.8	-2.6	2.2	-1.6	-2.7	1.3
Asthma	0.8	1.5	4.1	1.8	0.3	1.8	1.1	0.8	-0.4	-0.0	1.0	-2.0
Medication: Ibuprofen (e.g. Nurofen)	0.1	0.1	0.3	-0.1	0.4	0.2	0.0	0.4	-0.2	0.1	0.6	-0.2
Medication: Cholesterol lowering	0.3	0.4	0.8	-0.5	-0.9	-0.9	-0.3	-0.3	-0.2	-0.8	-0.7	0.5
Depression (self-reported)	0.3	0.3	1.0	1.0	-0.1	0.6	0.5	0.3	-0.0	0.9	0.5	0.2
Medication: Lansoprazole	0.8	0.9	3.6	-1.0	-1.9	-0.5	-0.1	-0.5	0.2	-0.4	-1.6	0.5
Prospective memory result	0.6	0.8	2.7	0.1	-0.2	-1.3	-0.8	-1.1	0.7	-0.3	-1.7	0.3
Lung cancer (father)	0.5	0.6	2.5	0.5	-1.0	-0.4	-0.4	-0.5	1.2	1.6	0.1	-0.1
Illnesses of mother	0.2	0.3	1.4	-0.5	1.2	-0.1	0.4	0.3	-0.2	0.4	-0.3	-0.2
Forced expiratory volume in 1-second (FEV1), Best measure	1.2	3.8	8.8	3.0	1.0	2.0	2.0	2.2	-2.5	-1.0	1.1	-1.8
Pulse wave Arterial Stiffness index	1.2	1.4	6.0	-0.4	2.4	-0.4	-0.6	0.4	0.0	2.5	0.3	0.1
Impedance of arm (left)	0.1	0.4	1.2	-1.1	0.6	-0.7	-0.6	-0.2	-0.2	-0.7	0.3	1.0
Arm fat mass (right)	0.7	2.8	9.0	-0.6	0.2	-1.0	-2.3	-1.8	3.0	2.3	0.7	0.8
Trunk predicted mass	1.0	5.7	10.6	3.3	0.8	2.8	2.5	2.9	-2.2	1.1	2.6	-2.1
Standing height	1.6	15.5	24.7	5.0	1.9	4.6	4.5	4.9	-4.0	0.9	4.5	-3.0
Length of working week for main job	1.7	1.9	4.3	-0.5	-1.4	-0.9	-1.0	-1.9	1.4	-1.6	-2.1	0.4
Exposure to tobacco smoke at home	0.6	0.7	1.3	-0.6	-0.2	-0.2	-1.1	-1.0	1.1	1.0	-1.0	-0.1
Breastfed as a baby	0.7	0.8	3.7	0.7	-0.3	1.3	1.0	0.1	-0.3	-1.9	0.6	0.2
Tense / ‘highly strung’	0.1	0.2	0.5	0.3	-0.4	0.5	0.4	-0.0	0.0	-0.5	0.7	-0.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.2	2.3	-0.3	-1.5	1.5	1.0	0.4	0.3	1.2	1.0	-1.4
Hair/balding pattern: Pattern 4	0.4	1.1	4.5	2.1	-0.6	0.5	0.5	0.2	-0.3	-1.5	1.1	0.8
Birth weight of first child	0.5	0.9	3.8	1.9	1.0	0.9	1.0	0.6	-0.3	0.1	0.7	-1.0
Peak expiratory flow (PEF)	1.6	3.8	6.9	2.1	0.6	2.6	2.6	2.2	-2.2	-0.8	1.6	-1.6
Pulse wave reflection index	0.2	0.3	1.2	0.3	1.1	0.1	-0.1	0.5	-0.9	0.2	-0.0	0.5
Ever highly irritable/argumentative for 2 days	0.2	0.2	0.8	0.3	0.3	-0.1	-0.4	-0.6	0.9	0.5	-0.5	-0.1
Loud music exposure frequency	0.3	0.4	1.7	-1.0	-0.0	-0.6	-0.2	-0.3	0.0	-0.3	-1.3	-0.4
Qualifications: O levels/GCSEs or equivalent	0.9	1.4	3.7	0.4	1.4	1.0	1.0	1.8	-1.9	0.7	0.9	-0.6
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	2.9	-0.4	0.8	-0.4	-0.1	0.4	-0.1	1.7	0.8	0.1
Blood clot in the leg (DVT)	2.0	2.6	5.4	-0.3	0.3	-2.3	-2.0	-1.9	1.8	0.8	-1.5	1.9
Medication: Paracetamol	0.4	0.6	2.8	0.7	1.2	0.1	-0.3	0.1	0.6	1.7	0.5	-0.5
Headache pain in last month	0.1	0.2	1.5	-0.2	-0.7	-0.0	-0.1	-0.3	0.2	0.1	-1.2	-0.3
Medication for cholesterol, blood pressure or diabetes	0.2	0.4	2.6	0.7	1.6	0.1	-0.2	0.1	-0.3	-0.0	0.1	0.2
Glaucoma (self-reported)	1.0	1.1	2.0	1.2	-1.2	1.3	1.2	0.8	-1.0	-1.4	-0.3	-0.5
Gout (self-reported)	0.9	1.2	3.5	-0.8	0.5	-1.5	-1.9	-1.1	0.7	0.5	0.8	1.2
Hypothyroidism/myxoedema (self-reported)	0.8	1.6	5.7	1.0	2.4	1.0	0.6	0.8	-0.2	1.4	1.7	0.1
Medication: Amlodipine	0.7	0.9	5.6	-2.4	-1.3	0.0	-0.1	-0.3	0.5	-0.2	-0.8	-0.1
Medication: Ventolin 100micrograms inhaler	0.6	0.7	2.0	0.9	-1.2	0.5	0.4	0.2	-0.7	-0.2	-1.4	-1.1
Birth weight	0.6	1.4	3.0	1.5	1.2	1.4	1.7	0.7	-0.9	-1.3	0.2	-0.6
Chronic bronchitis/emphysema (mother)	1.5	1.7	3.7	-0.2	1.2	-1.4	-1.7	-1.0	1.2	1.9	0.5	1.7
High blood pressure (siblings)	0.6	0.9	3.5	-1.0	-1.1	0.5	0.5	0.5	-1.2	-1.9	-0.3	-0.2
Forced vital capacity (FVC), Best measure	1.5	5.4	11.4	3.4	1.1	2.7	2.4	2.7	-2.6	-0.3	2.1	-2.2
Body fat percentage	1.6	6.2	19.1	-1.9	-0.2	-2.1	-3.3	-3.1	4.4	2.4	-0.1	1.5
Leg fat percentage (right)	1.9	7.1	21.5	-1.9	-1.6	-2.3	-3.3	-3.6	4.6	2.0	-1.1	1.2
Arm fat-free mass (right)	0.4	2.1	4.5	2.1	0.7	1.7	1.0	1.1	-0.0	2.0	1.8	-1.1
Exposure to tobacco smoke outside home	0.6	0.8	3.0	-1.7	-0.1	-0.0	-0.6	-0.5	1.0	1.0	0.3	-1.1
Comparative body size at age 10	0.2	0.5	1.3	1.1	0.3	0.6	1.0	0.7	-0.8	-0.5	-0.2	-0.3
Number of full brothers	1.7	2.2	4.0	-1.4	-1.4	-1.3	-1.5	-2.0	1.5	-1.2	-1.8	0.7
Worry too long after embarrassment	0.5	0.9	2.4	-1.1	0.6	-1.1	-0.9	-0.6	-0.2	-0.2	-1.6	1.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	2.0	-0.7	-0.6	-0.1	0.3	0.7	-1.4	0.2	-0.0	-0.0
Wheeze or whistling in the chest in last year	0.6	1.1	2.1	1.4	1.0	0.0	-0.6	-1.1	1.4	1.4	-0.0	-1.1
Number of children fathered	1.2	1.4	2.1	1.4	0.5	1.4	1.4	1.2	-1.2	-0.2	1.5	-1.0
Reason for reducing amount of alcohol drunk: Health precaution	1.1	1.3	3.3	-1.7	-1.8	-0.2	-0.2	-0.5	-0.3	-1.3	-1.8	-0.3
Age at first live birth	0.9	1.5	5.9	1.2	-0.4	1.1	0.9	0.9	-1.7	-2.4	0.5	-0.3
Pulse wave peak to peak time	1.0	1.2	4.8	0.7	-2.1	0.5	0.7	-0.1	-0.2	-2.2	-0.0	-0.2
Health satisfaction	0.5	0.6	1.8	1.1	-1.0	0.2	0.1	-0.7	1.3	0.6	-1.0	-0.1
Shortness of breath walking on level ground	0.4	0.5	2.4	-0.1	0.1	0.3	-0.6	-0.7	1.6	0.6	0.8	-0.2
Qualifications: College or University degree	0.9	2.8	9.5	0.8	2.1	1.0	1.3	2.3	-3.1	-1.3	1.0	0.5
Eye problems/disorders: None of the above	0.5	0.5	1.7	-1.1	-1.3	-0.6	0.1	0.0	-0.5	-0.8	-0.4	0.6
Mouth/teeth dental problems: Loose teeth	1.4	1.7	3.0	-0.9	-0.9	-1.4	-1.7	-1.7	1.3	-0.6	-1.7	0.9
Emphysema/chronic bronchitis	1.7	1.9	4.2	-2.0	-0.3	-1.6	-2.0	-1.4	1.5	1.1	-0.4	0.8
Medication for pain relief, constipation, heartburn	0.3	0.6	1.2	0.3	-0.6	1.1	1.1	0.6	-0.8	-1.0	0.5	-0.3
Neck or shoulder pain in last month	1.5	2.2	5.4	0.2	1.2	-1.9	-1.6	-1.7	1.2	0.6	-2.3	1.4
Medication: Blood pressure	1.1	2.0	7.0	-2.7	-2.6	-0.9	-0.8	-1.1	1.3	0.4	-0.1	0.4
Angina (self-reported)	1.6	2.1	3.5	-1.8	-1.1	-1.9	-1.5	-1.5	0.6	-1.3	-1.3	1.7
Migraine (self-reported)	0.5	0.6	1.9	0.1	0.8	-0.7	-0.5	-0.5	0.7	0.3	-1.4	1.0
Medication: Ibuprofen	0.2	0.2	0.8	-0.4	0.2	-0.1	-0.4	0.0	0.5	0.9	0.9	-0.1
Medication: Allopurinol	0.2	0.3	1.2	-0.5	0.2	-0.4	-0.7	-0.5	0.3	-0.2	1.1	0.6
Medication: Omeprazole	0.2	0.2	0.5	-0.7	0.1	-0.0	-0.4	-0.3	0.4	-0.6	0.5	-0.5
Medication: Seretide 50 evohaler	0.6	0.7	2.2	-0.5	1.2	0.1	-0.6	0.1	0.4	1.5	1.5	-0.1
Mean time to correctly identify matches	0.2	0.4	1.6	0.5	0.3	-0.1	-0.3	-0.4	0.8	1.3	0.2	-0.5
Heart disease (mother)	1.0	1.2	3.2	-0.4	-1.5	-0.8	-1.1	-1.5	1.8	0.4	-1.0	0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.8	0.9	3.3	1.5	0.1	0.7	0.6	1.0	-0.5	-0.1	1.8	-0.8
Whole body fat mass	0.8	3.3	11.2	-0.6	0.1	-1.1	-2.2	-2.0	3.3	2.5	0.7	0.8
Leg fat mass (right)	1.0	3.9	13.4	-0.7	-0.4	-1.4	-2.5	-2.5	3.7	2.4	-0.0	0.9
Arm predicted mass (right)	0.5	2.4	4.6	2.1	1.0	1.8	1.1	1.2	-0.1	2.1	1.9	-1.2
Pulse rate, automated reading	0.4	1.2	5.6	0.6	0.9	0.5	-0.0	0.4	0.8	2.4	1.0	-1.3
Alcohol intake frequency.	1.1	2.5	8.5	-0.6	-1.3	-1.7	-1.9	-1.6	1.0	-0.8	-2.9	1.0
Comparative height size at age 10	1.4	7.8	11.8	3.4	2.5	3.3	3.2	3.3	-2.9	0.6	2.5	-2.1
Number of full sisters	1.0	1.2	6.4	-1.5	-2.5	-0.5	-0.3	-0.3	0.1	-1.0	-0.3	0.8
Suffer from ‘nerves’	0.3	0.5	3.1	-0.6	0.4	-0.2	0.1	-0.3	0.7	1.8	0.1	-0.2
Overall health rating	0.7	1.6	5.4	-0.3	-1.0	-0.0	0.0	-1.2	2.3	2.1	-1.0	-1.0
Chest pain or discomfort	1.8	2.6	7.6	-1.2	-0.1	-1.5	-1.8	-2.4	2.8	1.7	-0.3	0.5
Had major operations	0.3	0.4	1.0	1.0	0.2	0.2	0.4	0.4	-0.9	-0.8	0.6	0.7
Age at last live birth	1.3	1.8	4.2	1.4	-0.4	1.4	1.6	1.2	-1.8	-2.1	0.6	-0.8
Family relationship satisfaction	0.2	0.3	0.7	0.3	-0.6	0.1	0.2	-0.3	0.3	-0.7	0.9	0.7
Leg pain on walking	0.4	0.5	2.2	1.0	-0.1	0.5	0.2	0.0	0.8	0.7	0.2	-1.5
Qualifications: NVQ or HND or HNC or equivalent	3.0	3.6	7.3	-0.7	1.5	-2.1	-2.4	-1.9	2.5	2.7	-1.1	1.0
Commuting to job workplace: Car/motor vehicle	1.1	1.2	2.7	-1.1	0.7	-1.3	-1.6	-1.2	1.2	0.5	1.0	1.1
Illness, injury, bereavement, stress in last 2 years	0.6	0.7	3.5	-0.2	1.9	-1.1	-1.0	-0.4	-0.1	-0.3	0.3	0.8
Medication: Aspirin	0.4	0.5	1.0	-0.3	-1.0	0.7	1.0	0.8	-0.8	-0.2	-0.0	-0.9
Supplements: Vitamin C	2.3	2.7	5.1	1.7	-1.2	1.4	2.2	1.8	-2.1	-0.6	-0.8	-2.3
Knee pain experienced in last month	2.1	3.3	12.9	0.8	3.3	-0.4	-1.2	-0.4	1.5	3.6	0.8	-0.0
Hypertension (Self-reported)	1.5	4.3	10.5	-3.2	-2.2	-1.3	-1.9	-2.4	3.2	1.0	0.4	0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.8	0.9	2.2	0.4	-1.1	-0.4	-0.1	-1.3	0.9	-1.5	-1.3	0.1
Illnesses of father: Heart disease	0.5	0.7	2.4	0.3	0.4	-0.6	-0.4	-1.1	0.6	-0.5	-1.6	1.1
Illnesses of siblings: Diabetes	0.5	0.7	2.7	-1.6	-0.9	-0.7	-0.4	-0.2	-0.1	-0.4	-0.8	0.9
Smoking status: Previous	0.1	0.2	0.6	0.4	0.5	0.1	-0.2	0.3	-0.4	0.1	0.8	-0.2
Forced expiratory volume in 1-second (FEV1), predicted	0.9	1.8	4.0	2.0	0.7	1.0	1.1	1.7	-1.6	-0.0	1.4	-1.5
Whole body fat-free mass	0.8	4.3	9.2	3.0	1.1	2.5	2.0	2.3	-1.5	1.4	2.5	-1.7
Leg fat-free mass (right)	0.5	2.6	5.3	2.3	1.3	1.9	1.3	1.6	-0.9	1.3	2.3	-1.1
Arm fat percentage (left)	1.1	4.3	12.6	-1.6	0.2	-1.7	-2.9	-2.5	3.5	2.0	-0.1	1.4
Average weekly red wine intake	0.1	0.1	0.4	0.4	0.0	0.2	0.3	0.2	-0.4	-0.7	0.1	-0.3
Handedness (chirality/laterality): Left-handed	0.4	0.4	2.7	1.6	-0.1	0.2	0.5	0.5	-0.2	-0.1	0.5	0.7
Mood swings	1.1	2.1	7.6	-1.8	1.2	-0.1	-1.1	-1.8	2.8	1.1	0.8	0.3
Loneliness, isolation	0.7	1.0	2.6	0.1	-0.1	-0.9	-0.9	-1.4	1.6	1.4	-0.7	0.2
Long-standing illness, disability or infirmity	0.7	1.1	3.4	0.2	0.6	-1.3	-0.6	-1.4	1.1	0.3	-1.9	1.0
Ever had bowel cancer screening	0.1	0.1	0.6	0.3	0.8	-0.3	0.3	0.1	0.1	0.1	-0.6	0.1
Diabetes diagnosed by doctor	1.0	1.6	4.8	-0.7	-1.3	0.1	-0.6	-0.8	2.2	1.7	1.8	-0.5
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	0.4	0.0	-0.5	-0.3	0.0	-0.7	0.3	-0.6	-0.2	-0.7
Friendships satisfaction	0.3	0.4	1.0	-0.2	0.5	-0.4	-0.6	-0.9	1.0	0.4	0.6	0.5
Qualifications: nursing, teaching	0.5	0.8	3.8	-0.2	0.3	0.2	0.5	1.2	-2.0	-1.1	-0.1	0.2
Commuting to job workplace: Walk	0.3	0.4	1.0	0.2	0.3	1.0	0.8	0.5	-0.5	-0.6	-0.1	-0.7
Eye problems/disorders: Cataract	0.4	0.5	2.0	-0.1	1.4	-0.2	-0.6	-0.2	0.5	1.3	0.5	-0.2
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	1.2	-0.2	-0.0	0.6	0.3	-0.2	0.2	-1.1	1.0	-0.6
Medication for cholesterol	1.2	1.9	5.1	0.8	1.7	1.3	1.1	1.8	-2.2	-0.8	1.2	-0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	4.8	5.7	10.3	-1.5	0.1	-3.0	-3.2	-2.9	3.2	1.3	-1.1	2.8
Back pain experienced in last month	1.4	2.1	5.2	0.1	0.0	-1.3	-1.8	-2.1	2.3	-0.4	-0.3	1.9
Mineral and other dietary supplements	0.6	0.7	1.3	-0.3	-0.9	0.9	0.9	1.1	-1.1	-0.7	0.2	-1.2
Breast cancer (self-reported)	1.0	1.2	6.5	-1.2	-0.0	0.2	1.0	0.6	-1.2	-0.0	-2.5	-0.7
Asthma (self-reported)	0.6	1.2	3.3	1.8	0.4	1.6	1.0	0.5	0.0	0.1	0.8	-1.8
Osteoporosis (self-reported)	0.3	0.4	2.5	-0.2	0.2	-0.3	-0.3	-0.2	0.8	1.6	0.0	0.2
Osteoarthritis (self-reported)	0.2	0.3	1.3	1.1	0.9	-0.2	0.1	-0.3	-0.1	-0.0	-0.4	0.2
Medication: Aspirin	0.3	0.4	0.7	-0.0	-0.7	0.7	0.6	0.8	-0.8	-0.2	0.3	-0.8
Medication: Gliclazide	0.7	0.8	2.0	-0.5	0.3	-0.9	-1.0	-0.8	1.3	1.4	-0.2	1.0
Illnesses of father: None of the above (group 1)	0.8	1.0	2.8	1.7	0.2	0.7	0.7	0.8	-0.1	0.9	1.7	-0.8
Smoking status: Current	0.3	0.4	1.6	-0.2	0.2	-0.4	-0.8	-0.9	1.3	0.1	-0.3	0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.0	2.2	5.2	2.3	0.3	1.4	1.3	1.5	-2.1	-1.5	0.6	-1.1
Whole body water mass	0.8	4.6	9.6	3.1	1.2	2.5	2.0	2.3	-1.5	1.5	2.6	-1.8
Leg predicted mass (right)	0.5	2.8	5.6	2.4	1.4	2.0	1.3	1.7	-1.0	1.3	2.3	-1.1
Arm fat mass (left)	0.6	2.6	8.0	-0.7	0.4	-0.9	-2.1	-1.6	2.8	2.5	0.8	0.7
Number of self-reported non-cancer illnesses	0.6	1.1	2.7	-0.1	0.1	-1.2	-1.1	-1.6	1.6	0.6	-0.1	1.3
Average weekly champagne plus white wine intake	0.3	0.4	2.6	0.1	-0.5	-0.2	-0.1	0.4	-0.6	0.2	0.2	1.6
Miserableness	1.5	2.5	6.6	-2.1	0.7	-1.1	-1.7	-1.7	2.6	2.0	0.2	0.3
Guilty feelings	0.6	0.9	2.7	-0.0	1.0	-0.9	-0.8	-0.7	0.7	1.1	-0.6	1.6
Wears glasses or contact lenses	0.4	0.5	2.0	1.4	0.2	-0.2	-0.3	0.3	-0.3	0.5	0.2	1.2
Ever taken oral contraceptive pill	0.6	0.7	2.0	-1.1	-1.3	0.2	0.3	0.4	0.4	1.4	0.5	-0.7
Hearing aid user	1.7	1.9	4.2	2.0	2.0	1.1	1.4	1.1	-1.3	-0.6	1.1	-1.0
Mother’s age at death	4.7	5.9	9.4	2.5	-0.8	3.0	3.1	2.8	-2.5	-2.1	2.4	-1.9
Financial situation satisfaction	0.2	0.3	1.1	-0.5	0.4	-0.3	-0.5	-0.8	1.0	0.3	0.2	0.1
Tinnitus: Yes, now most or all of the time	0.5	0.6	1.7	-0.0	0.9	0.9	0.9	0.6	-0.5	-0.1	0.9	-1.3
Commuting to job workplace: Public transport	0.7	0.8	2.2	0.2	0.3	1.1	1.5	1.0	-1.1	-0.9	0.1	-0.9
Eye problems/disorders: Glaucoma	2.8	3.3	7.2	2.4	-0.5	2.7	2.3	1.8	-1.6	-1.4	1.1	-1.4
Medication: Blood pressure	0.6	1.2	3.8	-1.2	-2.0	0.6	0.4	-0.9	1.6	-0.1	-0.2	-1.2
Pain type(s) experienced in last month: Hip pain	1.6	2.1	3.5	-0.5	1.3	-1.6	-1.9	-1.1	1.5	1.7	-1.1	1.7
Supplements: Fish oil (including cod liver oil)	0.1	0.2	0.5	0.6	0.1	-0.2	-0.2	-0.7	0.4	-0.0	-0.7	-0.3
High cholesterol (Self-reported)	0.5	0.9	4.0	0.8	-2.0	0.4	0.9	-0.1	-0.1	-1.7	-0.0	0.2
Medication: Bendroflumethiazide	0.9	1.4	4.1	-1.6	-0.9	-1.0	-1.3	-1.5	2.0	0.3	0.2	0.7
Medication: Paracetamol	1.0	1.5	7.6	1.3	1.1	0.2	-0.3	0.2	1.1	2.8	1.1	-0.9
Medication: Lisinopril	0.8	1.0	2.8	-0.4	-0.9	1.5	1.0	0.4	0.9	0.9	1.7	-0.8
Medication: Atorvastatin	1.5	1.8	3.6	1.8	1.9	1.0	1.2	1.4	-1.7	0.1	1.3	-0.8
Illnesses of father: High blood pressure	0.6	0.8	1.9	-0.6	-0.3	1.1	0.7	0.8	-1.3	-1.4	0.7	-0.2
Alcohol drinker status: Never	2.1	2.5	9.3	-0.9	-2.2	-0.6	0.3	-0.5	-0.8	-2.4	-3.0	0.6
Ever smoked	0.4	0.8	4.6	0.7	0.9	0.6	-0.3	0.4	0.2	0.6	2.1	0.4
Basal metabolic rate	0.5	3.0	6.2	2.5	1.0	2.0	1.3	1.6	-0.7	1.8	2.4	-1.4
Leg fat percentage (left)	1.8	6.5	18.9	-1.8	-1.2	-2.2	-3.4	-3.3	4.3	2.3	-0.8	1.4
Arm fat-free mass (left)	0.5	2.4	4.8	2.2	0.7	1.8	1.1	1.3	-0.3	2.0	2.0	-1.4
Number of operations (self-reported)	0.6	0.9	2.0	0.3	1.0	1.3	1.2	1.0	-0.6	-0.1	1.4	-0.6
Average weekly beer plus cider intake	2.1	3.1	8.0	1.8	0.0	2.3	1.6	1.7	-0.7	1.6	1.7	-2.8
Irritability	0.2	0.4	1.2	-1.1	0.8	-0.0	-0.5	-0.3	0.8	0.6	0.2	-0.4
Risk taking	0.6	0.9	5.4	-0.1	2.3	-0.6	-0.3	-0.1	-0.6	0.1	-1.2	0.3
Ever had prostate specific antigen (PSA) test	0.2	0.2	0.8	-0.4	0.2	-0.5	-0.4	0.2	-0.2	0.9	0.1	0.8
Fractured/broken bones in last 5 years	1.0	1.3	3.4	0.5	0.6	-1.3	-1.2	-1.8	1.9	0.2	-0.9	0.4
Age started oral contraceptive pill	0.3	0.3	1.0	-1.0	0.8	0.2	-0.4	0.2	0.3	0.7	-0.1	0.8
Diastolic blood pressure, automated reading	1.1	3.5	14.0	-1.9	-1.4	-1.0	-1.9	-2.6	3.7	0.8	0.2	-0.2
Ever depressed for a whole week	1.0	1.2	2.9	-0.6	-1.7	-0.8	-0.8	-1.6	1.5	-0.3	-0.9	1.0
Unable to work because of sickness or disability	0.4	0.5	1.4	-0.0	-1.1	-0.1	0.2	0.5	-0.5	0.5	-1.0	-1.2
Commuting to job workplace: Cycle	2.2	2.6	5.7	2.2	0.0	2.0	2.4	1.5	-1.7	-1.7	0.7	-0.8
Myopia	0.4	0.6	2.3	-0.7	-1.0	-0.8	-0.2	-0.4	0.7	-0.0	-1.5	0.6
Vascular/heart problems diagnosed by doctor	1.4	3.8	9.7	3.1	3.1	0.9	1.5	2.0	-2.7	-0.5	0.3	-0.6
Cholesterol lowering medication	0.2	0.3	1.6	-0.2	-1.3	0.0	0.1	-0.1	0.2	0.3	-0.8	-0.4
Medication: Omeprazole (e.g. Zanprol)	0.3	0.3	0.9	-1.0	0.9	-0.3	-0.6	-0.3	0.4	-0.0	0.5	-0.5
Pain experienced in last month	1.1	1.8	4.9	-0.3	-0.3	1.4	1.4	1.5	-1.6	-1.2	2.2	-0.9
Supplements: Calcium	1.7	1.8	3.4	1.3	-1.4	1.9	1.8	1.4	-1.1	-0.4	0.4	-1.6
Basal cell carcinoma (self-reported)	0.6	0.7	2.2	1.0	0.8	1.2	0.7	0.6	0.1	0.5	1.5	-0.1
Heart attack/myocardial infarction (self-reported)	1.9	2.5	7.5	-0.7	-0.5	-1.8	-1.4	-1.2	-0.3	-2.0	-2.7	1.8
Deep venous thrombosis (DVT) (self-reported)	2.4	3.0	6.0	-0.5	0.5	-2.4	-2.2	-2.1	2.0	1.0	-1.4	2.2
Heart disease (siblings)	1.2	1.4	5.0	-2.2	0.3	-1.4	-1.6	-0.7	0.5	0.8	-1.0	1.0
Alcohol drinker status: Previous	0.6	0.7	1.5	-0.6	-0.8	-0.4	-1.0	-1.0	0.9	-0.4	-1.2	-0.3
Pack years of smoking	0.2	0.4	1.5	-0.4	0.7	-0.5	-0.8	-0.1	0.1	1.2	0.2	0.3
Impedance of whole body	0.2	1.1	2.9	-1.7	-0.7	-1.3	-1.1	-1.1	0.9	-0.6	-0.6	1.0
Leg fat mass (left)	0.9	3.7	12.2	-0.7	-0.3	-1.3	-2.4	-2.3	3.5	2.5	0.2	1.0
Arm predicted mass (left)	0.5	2.4	5.2	2.3	0.7	1.7	1.0	1.2	-0.1	2.0	2.1	-1.3