Hub : Genes

FAM161A

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Tibial	0.1140	0.0469	1.1e-03	0.023	NA	0.052	NA	0.034	6.1e-03	NA	6.7e-05	NA	1.1e-03
2	GTEx	Stomach	0.2490	0.0920	3.0e-03	0.002	NA	0.005	NA	-0.003	2.4e-01	NA	1.8e-01	NA	4.7e-01
3	GTEx	Testis	0.3520	0.0750	3.6e-06	0.191	NA	0.176	NA	0.205	6.7e-09	NA	2.9e-08	NA	1.8e-09
4	GTEx	Thyroid	0.1140	0.0460	1.0e-04	0.033	NA	0.058	NA	0.053	1.3e-03	NA	3.1e-05	NA	7.0e-05
5	YFS	Blood	0.0207	0.0114	2.3e-02	0.002	0.004	0.008	0.005	0.006	4.7e-02	0.01500	6.7e-04	0.006	4.1e-03
6	TCGA	Esophageal Carcinoma	0.3130	0.1320	3.3e-03	-0.009	0.072	0.103	NA	0.001	9.1e-01	0.00270	3.7e-04	NA	2.9e-01
7	TCGA	Pancreatic Adenocarcinoma	0.0830	0.0450	4.4e-03	0.000	0.022	0.005	NA	0.013	3.3e-01	0.04000	1.9e-01	NA	8.9e-02
8	TCGA	Thyroid Carcinoma	0.0750	0.0370	1.9e-03	0.018	0.028	0.034	NA	0.010	5.9e-03	0.00086	2.9e-04	NA	3.4e-02

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	0.5	0.8	2.0	1.0	-1.4	0.3	-0.8	-0.5	-1.2	0.3	0.8
Bipolar Disorder or Schizophrenia	0.1	0.1	0.5	0.7	-0.2	0.1	-0.4	-0.2	-0.1	0.1	0.5
Depressed Affect (Nagel 2018)	0.7	1.4	3.5	1.2	-0.8	-1.4	1.3	0.1	1.9	1.5	-0.3
Depression (Nagel 2018)	0.6	0.9	4.5	-0.3	0.1	-1.4	0.1	-0.8	2.1	0.3	-0.5
Intelligence (Savage-Jansen 2018)	0.4	1.2	6.4	0.2	1.0	0.1	0.2	2.5	-0.6	0.1	1.4
Neuroticism (Nagel 2018)	0.6	1.4	3.7	1.0	-1.9	-1.1	1.0	0.7	1.6	1.2	0.4
Schizophrenia (2018)	0.1	0.2	0.5	0.1	0.7	0.0	0.1	0.2	0.6	-0.1	0.6
Schizophrenia vs Biploar Disorder	0.7	0.9	2.8	-0.3	1.5	0.1	0.7	1.7	0.5	-0.4	-0.9
Worry (Nagel 2018)	0.7	1.6	5.6	-0.1	-2.4	-1.2	0.6	0.4	1.7	1.0	1.1
Alzheimer’s Disease (in mother)	0.8	0.9	1.9	1.2	-0.4	-1.4	-0.1	-1.1	0.6	1.0	1.1
Alzheimer’s Disease (in father)	1.0	1.1	2.2	0.0	-1.3	1.5	-1.2	1.4	-0.5	-0.4	0.9
Alzheimer’s Disease (including proxy)	0.7	1.0	2.1	1.0	-1.2	-1.0	-0.7	-0.9	0.7	0.9	1.5
Crohns Disease (2017)	0.3	0.6	3.3	0.0	-1.8	-0.4	-0.1	1.1	-0.0	0.4	-0.7
Irritable Bowel Disease (IBD)	0.9	2.1	6.0	1.3	-2.4	0.2	1.5	2.4	0.6	0.7	0.3
Ulcerative Colitis (UC)	1.5	2.8	8.0	1.3	-2.5	1.2	1.9	2.8	0.3	0.3	1.1
Major Depression (MDD)	0.3	0.3	0.7	-0.3	0.8	-0.1	-0.6	0.6	0.7	-0.3	-0.9
Reaction Time	0.9	1.7	8.0	0.4	0.9	-1.8	0.3	-2.8	0.2	0.2	0.9
Verbal and Numeric Reasoning (VNR)	0.5	1.2	7.7	-0.3	0.6	0.3	-0.8	2.8	-0.9	-0.4	0.1
Breast Cancer	0.5	1.3	4.2	1.4	-0.4	0.4	2.0	0.4	-1.4	1.2	0.3
Ovarian Cancer	0.6	0.8	2.3	1.5	0.1	-0.4	1.4	1.0	-0.5	0.8	0.5
Prostate Cancer	0.4	0.6	2.7	-0.1	-0.9	1.6	-0.0	0.2	-0.1	-0.4	1.1
Age at First Birth	0.9	1.2	6.9	1.5	0.3	0.6	0.5	2.6	-0.3	0.2	0.2
Bipolar Disorder (2011)	0.8	0.8	4.2	0.0	-0.2	-0.8	-0.8	-2.1	-0.3	0.4	0.7
Body Mass Index (BMI) (2010)	0.7	0.9	2.9	-0.5	0.1	-1.0	-0.7	-1.5	0.4	0.2	-1.7
Coronary Artery Disease (CAD)	1.1	1.3	2.9	-0.8	-0.7	-0.5	-1.7	-1.1	1.2	-1.6	-0.5
Crohns Disease (2012)	0.4	0.7	2.4	0.1	-0.0	-1.6	0.7	0.4	1.0	1.3	-0.2
Mean Putamen Volume	1.0	1.1	3.2	-0.8	1.6	-1.1	0.2	-0.8	1.8	0.7	0.4
Fasting Glucose	1.5	1.8	5.5	-0.1	1.0	1.8	-0.5	2.3	-0.7	-2.0	-0.4
HbA1C	1.1	1.2	4.0	1.3	2.0	-0.6	1.9	-0.2	0.2	0.4	-0.1
HDL Cholesterol	0.6	0.9	4.0	1.1	1.1	0.4	-0.0	2.0	0.1	-0.8	-0.3
LDL Cholesterol	0.3	0.5	1.6	-0.1	0.8	-0.6	0.5	0.1	1.1	0.3	-1.3
Lupus	2.2	3.3	6.7	-0.0	1.6	-2.4	2.2	0.4	2.4	2.6	-0.1
Neuroticism (2016)	0.7	1.1	6.3	-0.2	-0.2	-0.6	0.6	0.9	2.5	0.7	-0.1
Primary Biliary Cirrhosis	1.2	1.7	4.0	-0.2	0.2	1.9	-2.0	1.5	0.2	-1.3	-1.5
Rheumatoid Arthritis	1.3	1.7	3.9	-2.0	-0.8	0.8	-1.5	-1.6	-0.4	-1.9	-0.2
Schizophrenia (2014)	0.1	0.2	0.5	0.2	0.5	0.1	-0.3	0.6	0.7	-0.2	0.2
Triglycerides	0.0	0.0	0.1	-0.2	0.2	0.4	0.3	-0.0	0.0	-0.1	-0.3
Type 2 Diabetes (T2D) (2012)	0.7	0.8	1.8	-0.7	-0.6	1.2	-0.7	1.0	-1.3	-0.9	-0.2
Ulcerative Colitis	2.8	4.1	10.3	2.3	-1.1	0.0	3.2	3.2	0.9	1.8	1.2
Blood Eosinophil Count	0.4	2.9	7.8	-2.0	1.8	-0.9	-2.0	-2.8	-0.8	-1.4	-0.6
Blood Platelet Count	0.1	1.6	10.0	-0.8	3.2	-1.0	-0.4	-0.3	-0.2	-1.0	-0.2
Blood Red Count	1.6	15.5	44.7	-2.9	-1.5	-0.2	-6.7	-1.9	1.3	-5.2	-6.1
Blood White Count	0.9	6.5	19.8	-2.1	3.8	-3.1	-1.1	-4.5	-1.3	0.1	-0.4
Heel T-Score	0.3	2.2	5.8	-1.8	-0.5	1.8	-1.8	0.5	1.0	-2.4	-0.8
BMI	0.4	2.4	7.0	2.0	0.1	-1.4	1.3	-1.0	2.6	1.7	-0.4
Height	0.2	2.9	14.2	1.1	0.9	0.2	1.6	3.8	-1.6	1.3	-0.8
Waist Hip Ratio (WHR)	0.2	1.1	2.2	1.1	0.0	-0.8	1.4	-0.1	-0.8	1.4	1.5
Systolic Blood Pressure	0.3	1.5	4.4	1.6	1.4	1.2	1.2	0.2	-0.1	-0.1	2.1
Smoking Status	0.7	1.7	4.3	0.6	2.1	-1.5	0.6	-1.2	-2.1	0.7	0.4
Allergy or Eczema	0.3	0.7	2.7	0.5	-0.8	-0.3	0.7	1.6	0.6	1.2	0.3
Cardiovascular Disease	1.2	4.0	10.4	2.3	2.3	-1.0	1.9	-1.7	0.9	1.7	3.2
Hypothyroidism (self reported)	0.4	0.8	1.8	0.0	-1.3	-0.5	1.4	0.8	0.4	1.1	-0.9
Respiratory disease	0.3	0.7	1.5	-0.4	-1.2	-0.1	0.5	0.1	1.1	1.2	1.1
Type 2 Diabetes (T2D) (2018)	0.5	0.9	3.5	-0.8	0.2	-0.4	-1.2	-0.9	-0.1	-1.0	-1.9
Lung FEV1/FVC ratio	0.7	3.6	9.6	-0.9	-3.1	1.2	-1.4	2.0	2.3	-1.4	-2.0
Lung FVC	0.3	1.5	3.0	-1.1	0.7	0.4	-1.3	-1.7	-1.0	-1.4	-1.7
Neuroticism	0.8	2.0	6.5	0.5	-2.3	-1.3	0.9	-0.5	2.5	1.1	0.6
Chronotype (morning person)	1.0	2.3	10.7	-1.1	-1.4	-1.0	-1.0	0.8	-1.2	-0.4	-3.3
Hair Pigment	0.2	5.4	15.8	4.0	1.0	-1.5	3.7	-0.0	1.0	2.4	1.9
Tanning	0.1	0.7	1.8	1.0	-0.8	1.1	0.1	1.3	-1.0	0.5	-0.4
Hand grip strength (left)	0.9	2.4	6.2	2.5	0.9	-0.1	1.9	1.9	-0.9	1.9	-0.7
Number of treatments/medications taken	0.8	1.4	3.7	-1.9	-1.3	0.4	-0.4	-1.6	1.6	-0.2	0.5
Average weekly spirits intake	0.8	1.0	4.9	2.2	0.4	0.5	1.0	0.2	0.3	-0.3	1.0
Sensitivity / hurt feelings	0.7	1.2	3.9	1.6	-1.3	1.2	0.4	0.2	0.3	0.1	2.0
Frequency of depressed mood in last 2 weeks	2.5	3.5	13.1	0.5	1.2	-2.6	1.9	-0.7	3.6	1.6	-0.4
Hearing difficulty/problems: Yes	0.6	1.0	4.3	0.4	-0.8	0.1	0.8	-0.4	0.0	1.4	2.1
Relative age of first facial hair	0.1	0.2	0.5	0.7	-0.5	0.0	-0.2	0.7	-0.0	0.2	-0.3
Other serious medical condition/disability diagnosed by doctor	1.3	1.7	6.1	0.3	-0.3	0.9	0.7	2.5	2.4	-0.3	-0.7
Ever used hormone-replacement therapy (HRT)	0.9	1.1	2.6	0.4	0.6	1.6	-0.7	1.6	-0.3	-1.3	0.7
Ever had hysterectomy (womb removed)	1.0	1.2	6.6	1.0	-0.8	1.0	0.2	-0.4	0.1	-0.0	2.6
Systolic blood pressure, automated reading	0.6	1.6	8.1	0.8	0.2	0.3	1.4	-0.4	0.6	1.3	2.8
Eye problems/disorders: Diabetes related eye disease	0.6	0.6	1.6	0.6	1.1	0.2	0.4	1.3	-0.8	-0.8	-0.2
Angina	0.3	0.4	1.5	0.3	-0.3	0.9	-1.2	-0.1	-0.5	-0.6	0.1
Medication for hormone replacement therapy	2.1	2.4	5.4	-0.6	-0.9	2.3	-1.9	1.8	0.2	-2.2	-0.9
Vitamin and mineral supplements	1.3	1.7	7.0	1.7	0.7	1.0	0.6	2.6	-0.6	0.2	1.3
Supplements: Zinc	0.2	0.2	0.5	0.7	0.5	-0.2	0.7	0.4	0.2	0.5	0.3
Medication: Co-codamol	2.3	2.6	5.3	1.6	1.3	-1.3	2.3	-0.7	1.9	1.6	1.6
Medication: Metformin	0.9	1.2	2.8	-1.1	-0.7	0.4	-1.7	-0.7	-0.5	-1.3	-1.6
Diabetes (father)	1.5	1.8	7.5	0.5	0.5	-1.7	1.2	-0.1	2.7	0.9	-1.2
Diabetes (mother)	0.7	0.9	3.7	0.4	0.3	-0.9	0.9	-0.6	1.9	1.1	-0.0
Severe depression (siblings)	0.4	0.5	1.2	-0.9	0.6	-1.1	-0.6	-0.7	0.5	0.2	0.5
Pack years adult smoking proportion	1.1	1.7	4.6	0.5	2.1	-1.6	0.4	-2.0	0.7	0.6	-0.9
Impedance of leg (right)	0.2	0.8	2.0	-1.3	-0.2	0.3	-1.1	-0.5	-0.8	-1.4	-0.6
Leg fat-free mass (left)	0.3	1.5	3.3	1.6	1.0	0.3	1.7	1.8	0.9	1.1	0.4
Trunk fat percentage	0.1	0.5	2.1	0.7	0.3	0.3	0.4	-0.7	1.5	-0.1	0.7
Hand grip strength (right)	0.4	1.0	4.8	0.2	1.4	-0.4	-0.3	0.6	-0.6	0.2	-2.2
Townsend deprivation index at recruitment	0.3	0.4	1.8	-0.3	0.5	-0.8	-0.0	-0.6	-0.1	0.3	1.4
Current tobacco smoking	0.8	1.3	6.9	0.2	0.8	-1.4	0.0	-2.6	0.2	0.4	0.6
Average weekly fortified wine intake	0.6	0.6	1.8	-1.1	-0.6	-0.2	-0.6	-1.3	-0.1	-0.5	1.1
Maternal smoking around birth	1.2	1.7	5.9	-2.4	0.8	-0.9	-1.5	-1.9	-0.1	-0.7	0.2
Fed-up feelings	0.8	1.5	6.2	0.3	-0.7	-1.4	0.9	-1.0	2.5	1.0	-0.7
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.5	3.4	0.1	0.3	0.2	0.3	-0.2	1.8	-0.3	0.5
Relative age voice broke	0.2	0.2	0.5	-0.2	0.4	-0.1	-0.7	-0.5	0.1	-0.7	-0.7
Taking other prescription medications	0.8	1.2	2.9	-1.6	-0.8	-0.7	-0.0	-1.5	1.7	0.5	-0.7
Age when periods started (menarche)	1.3	3.2	9.3	-1.5	-0.0	0.9	-2.9	-1.4	-0.8	-3.1	-1.5
Bilateral oophorectomy (both ovaries removed)	2.0	2.3	4.4	1.9	0.0	0.5	1.5	2.1	1.5	1.2	2.1
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.1	2.2	-1.0	1.4	0.4	-1.3	0.8	0.0	-0.9	-1.5
Tinnitus: Yes, but not now, but have in the past	0.6	0.6	2.3	-0.2	-1.1	-0.6	-0.5	-1.5	-0.7	0.5	0.4
Qualifications: CSEs or equivalent	1.0	1.3	3.2	1.4	0.2	-0.3	1.6	0.8	1.3	0.1	-1.8
Serious illness, injury or assault to yourself	1.4	1.8	4.3	-2.0	-1.0	-0.9	-1.5	-2.1	0.1	-0.3	-1.2
High blood pressure	0.7	2.0	9.4	1.4	1.1	1.1	1.2	0.3	0.1	0.5	3.1
Hayfever, allergic rhinitis or eczema	0.6	1.3	2.7	0.5	-1.3	-0.4	1.2	1.6	1.6	1.3	-0.5
Multivitamins +/- minerals	1.5	2.0	8.1	-1.7	-0.7	-0.9	-0.7	-2.8	1.6	-0.4	0.4
Stomach or abdominal pain in last month	0.2	0.3	0.7	0.4	0.5	0.8	-0.2	0.2	-0.5	-0.8	-0.5
Supplements: Glucosamine	0.7	1.0	4.1	0.0	2.0	0.9	-0.3	-0.2	-0.8	-0.1	1.4
Diverticular disease/diverticulitis (self-reported)	0.6	0.7	2.7	1.6	1.1	0.2	0.8	0.5	0.8	-0.3	0.7
Medication: Atenolol	0.7	0.9	2.6	1.4	0.6	1.6	-0.2	0.2	-1.0	-0.9	0.8
Medication: Levothyroxine sodium	0.3	0.5	2.0	-0.4	-0.6	0.3	0.9	-0.5	1.4	-0.1	0.5
Sitting height	0.3	2.1	9.5	0.9	1.4	0.4	1.4	3.1	-0.4	0.3	-1.4
Chronic bronchitis/emphysema (father)	1.3	1.5	5.0	-0.3	-2.2	1.2	-0.3	-1.1	-0.2	-0.1	2.1
High blood pressure (mother)	0.5	0.6	2.6	-1.2	0.5	0.4	0.6	-0.2	1.6	-0.2	0.4
Body mass index (BMI)	0.2	0.9	3.2	0.9	-1.1	0.3	0.2	-1.2	1.8	0.4	0.5
Impedance of leg (left)	0.3	1.3	3.3	-1.3	-0.0	0.8	-1.6	-0.3	-1.1	-1.8	-1.0
Leg predicted mass (left)	0.3	1.4	3.5	1.6	1.0	0.4	1.6	1.9	0.8	1.0	0.3
Trunk fat mass	0.1	0.5	2.0	1.1	0.4	0.2	0.7	-0.1	1.4	0.3	0.2
Waist circumference	0.1	0.4	2.2	0.5	-0.2	-0.1	0.2	-0.9	1.5	0.3	0.3
Number of incorrect matches in round	1.7	2.8	9.7	-1.8	-1.2	-1.1	-0.9	-3.1	-1.0	1.9	1.0
Past tobacco smoking	0.5	0.9	2.0	-1.0	-0.9	0.1	-1.3	-0.6	1.1	-0.7	-1.4
Alcohol usually taken with meals	1.6	2.6	7.0	-1.3	1.7	-0.5	-1.9	0.2	0.4	-2.6	-2.3
Nervous feelings	0.9	1.6	4.1	1.2	-0.6	-1.2	1.8	0.4	2.0	1.1	0.8
Frequency of tenseness / restlessness in last 2 weeks	1.9	3.0	8.0	0.8	2.1	-2.4	1.8	-0.6	2.8	1.2	-0.2
Hearing difficulty/problems with background noise	0.5	0.8	1.6	1.3	-1.1	0.1	0.9	0.6	-1.0	1.1	-0.1
Hair/balding pattern: Pattern 2	1.2	1.6	3.4	-1.8	-0.8	0.9	-1.2	-1.0	-1.7	-1.3	-0.8
Had menopause	0.3	0.4	1.7	-0.5	-0.0	-1.3	0.2	-0.4	0.7	0.7	0.5
Had other major operations	0.3	0.4	1.5	1.2	0.0	-0.2	0.6	-0.3	0.0	-0.2	1.1
Forced vital capacity (FVC)	0.5	1.9	3.8	0.1	1.9	1.4	-0.4	1.1	-1.9	-1.6	-1.4
Heel bone mineral density (BMD) T-score, automated (right)	0.6	1.3	4.0	-0.2	0.8	2.0	-0.8	1.7	0.6	-1.3	-0.3
Ever unenthusiastic/disinterested for a whole week	1.1	1.4	4.2	-1.4	0.1	0.3	-0.8	-0.6	2.0	-1.4	-1.3
Qualifications: None of the above	0.4	0.9	3.0	1.0	0.9	-0.6	0.2	-1.7	-0.2	1.1	1.0
Financial difficulties in last 2 years	0.6	0.8	4.3	-0.2	-0.9	0.4	0.6	0.5	2.1	0.2	0.2
Mouth/teeth dental problems	0.1	0.2	0.4	-0.1	0.6	0.1	0.5	0.2	-0.2	0.5	0.5
Heart attack	0.7	0.9	3.1	-0.2	-0.2	0.9	-1.8	-0.3	-1.3	-1.2	-0.4
Allergy	0.6	1.3	3.6	0.4	1.9	0.3	-1.3	-1.4	-0.6	-1.5	-0.4
Pain all over the body in last month	2.4	2.6	5.8	-2.3	0.1	0.1	-2.4	-1.7	1.1	-1.8	-1.3
Diabetes (self-reported)	0.8	1.2	4.0	-0.8	-0.8	-0.5	-1.3	-0.8	0.9	-1.0	-2.0
Hayfever/allergic rhinitis (self-reported)	1.0	1.3	3.7	1.4	0.4	0.3	1.4	1.3	1.9	0.6	0.6
Medication: Ramipril	1.2	1.5	9.1	1.1	3.0	-0.2	0.2	1.2	-0.1	0.5	0.4
Medication: Simvastatin	0.8	1.2	3.9	-0.7	-0.2	0.7	-1.4	-2.0	0.2	-1.5	0.5
Fluid intelligence score	0.6	1.2	8.2	-0.4	0.7	-0.1	-0.4	2.9	0.3	-0.4	-0.0
Illnesses of siblings	0.5	0.7	1.5	-0.6	-1.2	-0.6	-0.5	0.4	-1.2	-0.7	-1.0
Neuroticism score	1.1	2.2	4.8	1.9	-1.9	-0.4	1.6	0.9	2.2	1.2	0.7
Weight	0.1	0.7	1.7	1.3	-0.0	0.4	0.9	0.8	1.3	0.6	-0.1
Impedance of arm (right)	0.2	0.7	2.2	-0.8	1.4	-0.6	0.2	0.2	0.8	-1.5	0.3
Arm fat percentage (right)	0.3	1.0	5.2	1.0	-0.0	-0.1	0.6	-1.0	2.3	-0.1	1.0
Trunk fat-free mass	0.2	1.4	5.8	1.4	0.6	0.7	1.0	2.4	0.1	0.9	-0.9
Hip circumference	0.1	0.4	2.2	0.4	-0.3	0.5	-0.1	0.0	1.5	-0.3	-0.5
Time employed in main current job	0.8	0.9	2.7	1.0	-0.0	-0.7	1.1	-0.4	-0.1	1.6	1.4
Alcohol intake versus 10 years previously	0.7	1.1	2.4	-0.9	-0.1	1.4	-1.2	0.2	1.6	-1.4	0.3
Father’s age at death	1.5	2.0	8.2	-1.8	-2.9	1.0	-0.8	1.2	-0.7	-0.6	-0.8
Worrier / anxious feelings	0.5	0.9	4.6	0.1	-2.1	-0.5	0.4	0.4	0.8	0.7	0.8
Frequency of tiredness / lethargy in last 2 weeks	1.3	2.1	10.5	0.7	1.9	-0.0	1.1	0.9	3.2	-0.3	-0.1
Falls in the last year	0.4	0.6	1.9	-0.5	0.6	0.5	-0.8	-0.0	-0.2	-1.1	-1.4
Hair/balding pattern: Pattern 3	1.5	2.3	4.8	2.1	2.2	-1.4	0.9	2.1	0.7	1.1	-0.2
Number of live births	0.3	0.4	1.2	-0.6	0.4	1.1	-0.7	-0.2	-0.7	-0.9	-0.4
Forced expiratory volume in 1-second (FEV1)	0.7	2.4	5.2	0.5	1.0	1.8	-0.7	2.2	-1.0	-1.8	-2.3
Pulse rate	0.8	1.3	7.1	-1.2	0.5	-1.1	0.0	-0.5	2.7	-0.5	-0.2
Happiness	1.4	1.7	5.4	-1.2	1.2	-1.1	-0.4	0.3	1.9	-0.6	-2.3
Noisy workplace	1.4	1.8	4.7	-0.9	2.2	-0.4	-1.6	-1.9	-0.9	-1.3	-0.2
Qualifications: A levels/AS levels or equivalent	0.6	1.4	6.3	0.0	1.0	0.2	-0.8	2.5	-1.1	-1.2	-1.0
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.5	1.9	-0.8	0.2	0.0	-0.8	-0.7	-1.4	-0.4	-0.0
Mouth/teeth dental problems: Dentures	0.4	0.7	1.9	0.5	0.9	-1.3	0.5	-0.3	-0.1	1.4	0.5
Asthma	0.5	1.0	4.1	-2.0	-1.2	-0.9	-0.7	-0.7	0.5	0.1	-0.5
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	2.0	0.6	-0.2	0.9	1.4	0.3	1.0	0.1	0.4
Medication: Cholesterol lowering	0.2	0.3	1.5	-0.3	0.8	-0.2	-1.2	0.1	-0.3	-0.5	-0.4
Depression (self-reported)	0.9	1.1	4.9	0.4	-2.2	-0.0	0.9	-0.6	1.4	0.4	0.5
Medication: Lansoprazole	1.3	1.5	6.2	-2.5	-0.3	-0.7	-1.4	-1.4	-0.8	-0.5	-0.6
Prospective memory result	0.3	0.3	0.8	-0.7	-0.5	-0.9	0.2	-0.4	-0.2	0.7	-0.6
Lung cancer (father)	0.6	0.7	2.1	-0.0	1.2	0.9	-1.1	0.6	-0.3	-1.4	0.1
Illnesses of mother	0.5	0.7	2.3	1.5	1.1	0.6	0.5	0.9	-0.3	-0.1	0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.4	3.8	0.4	0.6	1.1	-0.4	2.0	-0.8	-1.1	-1.9
Pulse wave Arterial Stiffness index	0.8	1.0	2.6	0.3	-0.4	-0.0	-1.3	-0.7	1.6	-0.8	1.4
Impedance of arm (left)	0.1	0.6	1.7	-1.3	0.8	-0.5	-0.2	0.5	-0.1	-1.3	-0.3
Arm fat mass (right)	0.2	0.9	4.0	1.2	-0.1	-0.1	0.9	-0.5	2.0	0.6	0.7
Trunk predicted mass	0.2	1.4	6.0	1.4	0.5	0.7	1.0	2.4	0.0	0.9	-1.0
Standing height	0.3	3.4	16.9	1.2	1.9	0.3	1.6	4.1	-0.6	0.8	-1.0
Length of working week for main job	1.1	1.2	5.7	-1.3	0.2	-1.2	-0.5	0.1	0.8	0.1	-2.4
Exposure to tobacco smoke at home	0.6	0.7	2.3	-0.5	-0.5	-0.9	-0.9	-0.8	0.3	0.0	-1.5
Breastfed as a baby	1.9	2.4	6.1	2.5	-0.2	-1.1	2.2	0.7	0.6	2.2	1.0
Tense / ‘highly strung’	1.3	2.2	5.5	0.7	-1.1	-1.2	1.4	-0.1	2.3	1.8	1.8
Seen doctor (GP) for nerves, anxiety, tension or depression	1.3	1.9	10.0	1.2	-0.2	0.2	1.3	1.5	3.2	-0.3	-0.4
Hair/balding pattern: Pattern 4	1.5	3.6	14.2	-1.8	-0.9	-1.5	-2.1	-3.8	0.3	-1.1	-1.6
Birth weight of first child	0.9	1.6	6.2	-1.7	-0.1	0.1	-1.3	0.9	0.9	-0.8	-2.5
Peak expiratory flow (PEF)	0.8	1.8	8.9	0.6	0.1	0.6	0.2	3.0	0.1	0.0	-2.2
Pulse wave reflection index	0.5	0.6	2.3	1.0	-0.2	1.1	-0.4	-0.2	0.1	-0.4	1.5
Ever highly irritable/argumentative for 2 days	1.4	1.7	11.0	0.8	-0.7	0.6	0.7	0.2	3.3	-0.4	0.8
Loud music exposure frequency	0.7	0.8	1.8	0.7	0.5	-0.7	1.3	0.7	0.2	1.3	1.0
Qualifications: O levels/GCSEs or equivalent	1.3	2.1	11.0	0.0	-0.0	1.6	0.0	3.3	-0.9	-1.0	-1.1
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	1.9	-0.2	-0.6	1.4	-0.3	0.6	0.2	-1.1	0.3
Blood clot in the leg (DVT)	1.3	1.7	8.9	-0.4	-1.3	1.2	-0.0	0.4	-3.0	0.7	1.0
Medication: Paracetamol	0.4	0.6	1.8	-0.5	-0.8	0.8	-0.7	-1.4	0.8	-0.7	-0.0
Headache pain in last month	1.1	1.8	6.8	-1.0	0.6	0.9	-1.8	-0.7	1.1	-2.6	-1.1
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	1.7	-0.2	-0.6	-0.5	1.3	0.3	1.0	0.4	0.2
Glaucoma (self-reported)	2.6	3.0	8.8	-3.0	-0.5	-1.6	-1.3	-2.5	2.0	-0.8	0.1
Gout (self-reported)	0.8	1.0	4.3	-0.1	0.8	-0.5	0.8	-0.3	-0.9	1.1	2.1
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	1.2	0.1	-0.4	0.2	1.1	0.9	1.0	0.5	-0.4
Medication: Amlodipine	0.6	0.8	5.6	-0.3	-0.2	-0.6	0.0	-2.4	-0.6	-0.2	0.3
Medication: Ventolin 100micrograms inhaler	1.6	2.0	4.3	-1.8	-2.1	1.0	-1.9	-0.4	-0.3	-1.7	-0.9
Birth weight	0.4	0.8	4.0	0.2	1.1	-0.8	0.4	0.7	0.2	-0.1	-2.0
Chronic bronchitis/emphysema (mother)	0.4	0.4	1.3	-0.5	1.1	-0.4	-0.0	-0.0	1.1	-0.2	-0.8
High blood pressure (siblings)	0.3	0.4	1.4	0.3	1.2	0.8	-0.2	-0.3	-0.4	0.1	1.0
Forced vital capacity (FVC), Best measure	0.3	0.9	2.0	-0.2	1.4	0.9	-0.5	0.8	-1.4	-1.0	-0.9
Body fat percentage	0.1	0.5	2.1	0.6	-0.2	0.1	-0.0	-1.0	1.4	-0.3	0.4
Leg fat percentage (right)	0.2	0.8	2.6	0.2	-1.2	-0.1	-0.3	-1.6	1.4	-0.2	-0.0
Arm fat-free mass (right)	0.2	0.8	3.3	1.1	0.2	1.2	0.4	1.8	-0.2	0.7	-0.5
Exposure to tobacco smoke outside home	0.8	1.1	2.9	-0.1	0.9	-1.2	-0.5	-1.7	1.7	-0.7	-0.4
Comparative body size at age 10	0.3	0.9	2.6	-1.6	-1.3	1.1	-0.5	-1.0	-0.4	-0.4	0.6
Number of full brothers	0.2	0.2	0.7	0.2	0.7	0.3	0.2	0.5	-0.8	-0.5	0.3
Worry too long after embarrassment	0.7	1.2	3.2	1.1	-0.9	0.5	1.3	1.8	0.4	0.9	1.0
Seen a psychiatrist for nerves, anxiety, tension or depression	1.5	2.0	6.1	0.1	-1.7	-1.2	-0.2	-0.3	2.3	0.0	-2.5
Wheeze or whistling in the chest in last year	0.4	0.8	3.4	-0.5	0.7	-0.5	-0.5	-1.9	1.1	-0.3	-0.2
Number of children fathered	0.4	0.5	1.5	0.6	-0.3	0.5	-0.2	1.2	-0.5	0.1	-1.2
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.5	1.3	0.4	-0.2	0.5	0.5	1.0	-1.2	0.8	-0.1
Age at first live birth	0.7	1.2	5.1	-1.1	0.4	-0.7	-0.5	1.6	0.2	-0.3	-2.2
Pulse wave peak to peak time	0.9	1.0	2.2	-0.2	0.4	0.2	1.5	1.1	-1.4	0.9	-1.3
Health satisfaction	0.7	0.9	3.1	0.4	1.5	0.7	0.5	0.6	1.8	-0.3	0.4
Shortness of breath walking on level ground	1.3	1.6	4.4	-1.4	0.1	-0.1	-1.2	-2.1	0.3	-1.4	-1.7
Qualifications: College or University degree	0.6	2.0	5.9	-1.7	-0.6	-0.3	-1.9	0.8	-0.0	-1.5	-2.4
Eye problems/disorders: None of the above	0.5	0.6	1.6	1.1	-0.5	1.3	0.9	1.0	0.0	0.3	-0.1
Mouth/teeth dental problems: Loose teeth	0.7	0.9	2.0	-0.1	-0.1	-1.1	0.4	-1.4	1.4	0.5	1.2
Emphysema/chronic bronchitis	0.4	0.5	1.5	0.3	-1.0	0.2	0.6	-0.3	0.8	0.3	1.2
Medication for pain relief, constipation, heartburn	0.2	0.3	0.8	0.5	0.0	-0.6	-0.0	0.2	-0.6	0.6	0.9
Neck or shoulder pain in last month	0.5	0.8	3.2	-0.3	1.2	-0.3	0.3	-1.8	0.3	-0.6	0.9
Medication: Blood pressure	0.5	0.9	3.3	0.6	-0.1	1.8	-0.9	0.7	-1.4	-0.7	0.3
Angina (self-reported)	0.2	0.3	1.2	0.3	-0.2	0.8	-1.1	-0.4	-0.2	-0.6	0.4
Migraine (self-reported)	0.6	0.7	2.0	-0.7	0.3	1.3	-0.3	-0.6	-0.5	-1.4	0.7
Medication: Ibuprofen	0.8	0.9	2.1	1.0	-0.4	1.3	1.4	0.8	1.2	-0.3	0.5
Medication: Allopurinol	0.7	1.0	3.2	-0.1	0.5	-1.8	0.7	-1.1	-0.7	1.3	0.7
Medication: Omeprazole	1.0	1.2	3.0	1.0	-0.1	-0.7	1.7	0.2	1.6	1.6	0.5
Medication: Seretide 50 evohaler	1.3	1.5	4.0	-2.0	-1.5	-0.4	-0.9	-1.6	0.8	-1.0	-0.5
Mean time to correctly identify matches	0.8	1.6	6.4	0.7	0.3	-1.6	0.1	-2.5	-0.4	0.5	1.6
Heart disease (mother)	1.9	2.4	4.8	-1.9	-2.2	-0.3	-2.0	-1.8	-1.3	-0.9	-0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.6	0.7	2.0	-0.3	1.3	-0.6	0.7	0.5	-0.2	0.5	-1.4
Whole body fat mass	0.1	0.5	2.3	0.9	-0.2	0.1	0.4	-0.6	1.5	0.2	0.3
Leg fat mass (right)	0.1	0.4	1.8	0.9	-0.5	0.3	0.2	-0.6	1.3	0.1	-0.1
Arm predicted mass (right)	0.2	0.8	2.9	1.2	0.3	0.9	0.6	1.7	-0.2	0.8	-0.5
Pulse rate, automated reading	0.3	0.8	3.2	-0.7	-0.9	-0.1	0.1	-0.9	1.8	-0.5	-1.0
Alcohol intake frequency.	0.2	0.6	1.8	0.1	-1.2	-0.4	-0.7	-0.3	0.8	-0.0	-1.4
Comparative height size at age 10	0.2	1.2	3.3	0.5	-0.3	0.9	1.5	1.8	-0.7	1.3	0.8
Number of full sisters	0.9	1.1	4.7	-0.2	-2.2	-0.0	-0.6	-1.3	0.9	-0.0	-1.2
Suffer from ‘nerves’	0.5	0.7	2.2	1.3	-0.5	0.6	0.6	1.5	0.8	-0.4	0.2
Overall health rating	0.7	1.4	3.0	0.8	1.2	-1.3	1.3	-0.7	1.7	1.4	0.6
Chest pain or discomfort	0.6	0.8	1.5	-1.2	0.1	0.6	-1.2	-0.7	1.2	-1.0	0.4
Had major operations	0.9	1.1	2.2	-1.4	0.2	-0.3	-1.1	-1.3	0.4	-1.0	-1.5
Age at last live birth	1.7	2.4	4.1	-2.0	-2.0	0.7	-1.9	0.2	-1.3	-1.2	-1.9
Family relationship satisfaction	1.7	2.0	8.5	-1.1	-0.4	-0.7	-1.9	0.5	0.7	-1.3	-2.9
Leg pain on walking	0.7	0.9	4.6	1.1	0.2	0.5	0.9	0.5	2.1	0.1	0.0
Qualifications: NVQ or HND or HNC or equivalent	1.4	1.6	6.7	-0.5	0.5	1.7	-1.0	-0.0	1.4	-2.6	-0.4
Commuting to job workplace: Car/motor vehicle	0.3	0.3	0.9	0.4	-0.3	1.0	-0.1	-0.3	-0.4	-0.7	0.7
Illness, injury, bereavement, stress in last 2 years	0.1	0.1	0.3	0.5	0.6	-0.2	0.2	-0.2	-0.5	-0.1	0.1
Medication: Aspirin	0.6	0.8	1.8	-0.0	1.1	0.4	-0.5	1.4	-1.2	-1.0	-0.5
Supplements: Vitamin C	2.1	2.5	5.1	2.2	0.8	-0.8	1.4	2.1	-0.9	0.9	-2.3
Knee pain experienced in last month	1.2	1.8	4.1	-1.4	0.0	0.7	-2.0	-1.8	0.3	-1.7	-1.3
Hypertension (Self-reported)	0.7	1.9	8.7	1.6	0.9	0.9	1.2	0.1	0.7	0.5	2.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.8	4.1	-0.8	-0.8	-0.0	0.5	-0.8	2.0	0.3	0.3
Illnesses of father: Heart disease	0.3	0.4	1.3	0.5	1.1	0.0	-0.5	0.6	-0.6	-0.1	-0.7
Illnesses of siblings: Diabetes	0.4	0.5	1.6	-0.7	-0.3	-0.6	0.0	-1.0	0.4	1.2	-0.7
Smoking status: Previous	0.4	0.7	2.6	0.3	0.7	-0.1	0.8	0.5	-1.6	0.4	1.1
Forced expiratory volume in 1-second (FEV1), predicted	0.8	1.7	4.4	0.6	1.6	-1.5	1.5	1.3	0.6	2.1	-0.0
Whole body fat-free mass	0.2	1.3	4.7	1.5	0.8	0.6	1.2	2.2	0.4	1.0	-0.4
Leg fat-free mass (right)	0.3	1.5	4.1	1.5	1.1	0.5	1.5	2.0	0.8	1.0	0.2
Arm fat percentage (left)	0.2	0.7	3.7	0.7	-0.2	-0.1	0.4	-0.7	1.9	-0.1	0.6
Average weekly red wine intake	0.2	0.4	0.9	0.4	1.0	0.0	-0.8	0.6	-0.0	-0.8	-0.1
Handedness (chirality/laterality): Left-handed	0.7	0.8	2.9	1.2	0.3	-0.5	1.7	1.0	-0.4	0.5	-0.7
Mood swings	1.5	2.6	9.0	1.5	-0.6	-1.6	2.1	-0.4	3.0	1.5	0.3
Loneliness, isolation	0.8	1.2	3.2	0.2	-1.8	-0.5	-0.2	-1.6	0.6	0.2	-1.7
Long-standing illness, disability or infirmity	0.6	0.9	4.2	-2.0	-0.3	1.1	-0.9	-0.2	0.6	-0.9	0.1
Ever had bowel cancer screening	0.2	0.2	0.8	-0.2	-0.4	-0.1	-0.4	0.1	-0.9	0.2	-0.6
Diabetes diagnosed by doctor	1.0	1.7	7.0	-0.4	-0.8	-0.4	-1.5	-0.9	0.8	-1.3	-2.6
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.7	1.8	1.3	-1.2	0.6	0.5	1.3	-0.2	0.2	0.2
Friendships satisfaction	3.4	4.3	16.2	-1.1	0.6	0.8	-2.5	1.0	0.8	-2.8	-4.0
Qualifications: nursing, teaching	0.7	1.0	4.7	-0.5	0.6	-0.3	-0.6	1.2	-0.3	-1.0	-2.2
Commuting to job workplace: Walk	0.5	0.6	1.4	-0.4	-0.6	0.1	-1.1	-1.0	-0.7	-1.2	-0.2
Eye problems/disorders: Cataract	0.4	0.4	2.2	0.0	-0.2	-0.1	-0.7	-1.5	0.7	-0.4	0.2
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	2.2	-0.5	-0.3	0.5	-1.2	0.0	-0.5	-1.5	-0.8
Medication for cholesterol	0.8	1.3	3.1	-0.8	0.5	-0.9	-0.4	1.5	-1.4	0.9	-1.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.5	2.2	-1.5	-0.9	-0.2	0.1	-0.8	-0.1	0.6	-0.5
Back pain experienced in last month	0.8	1.2	3.7	0.3	-0.5	1.9	0.6	-0.6	-1.5	0.5	1.4
Mineral and other dietary supplements	0.4	0.5	1.2	1.1	-1.1	0.1	0.5	0.8	-0.3	0.6	0.5
Breast cancer (self-reported)	0.4	0.5	1.4	-0.4	0.7	-1.2	0.4	-0.2	0.8	1.0	0.2
Asthma (self-reported)	0.4	0.8	3.9	-2.0	-1.1	-0.4	-0.8	-0.4	0.6	-0.1	-0.3
Osteoporosis (self-reported)	1.0	1.2	6.0	-0.6	-0.9	-0.9	-0.4	-2.4	1.2	0.0	0.5
Osteoarthritis (self-reported)	0.7	0.9	3.5	-1.9	-0.1	0.2	-1.1	-1.2	-0.5	0.0	0.8
Medication: Aspirin	0.7	0.8	2.9	-0.1	1.7	0.3	-0.6	1.0	-1.3	-0.9	-0.3
Medication: Gliclazide	3.4	3.9	11.5	-1.4	-3.3	0.4	-1.7	-1.5	-0.0	-1.0	-3.4
Illnesses of father: None of the above (group 1)	1.5	1.8	4.3	-1.3	1.0	-2.1	-0.2	-2.0	0.4	-0.2	-1.8
Smoking status: Current	0.6	0.9	4.8	0.2	0.8	-1.1	0.1	-2.2	0.3	0.3	0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.5	4.3	-0.7	-0.0	0.7	-1.7	0.0	-0.9	-2.1	-1.8
Whole body water mass	0.2	1.4	4.9	1.5	0.8	0.7	1.3	2.2	0.4	0.9	-0.3
Leg predicted mass (right)	0.3	1.4	4.0	1.5	1.0	0.5	1.4	2.0	0.7	0.9	0.1
Arm fat mass (left)	0.1	0.6	2.7	0.9	-0.5	0.3	0.4	-0.5	1.6	0.2	0.3
Number of self-reported non-cancer illnesses	0.9	1.5	6.5	-0.2	-0.8	0.4	0.7	-0.4	2.5	0.5	1.9
Average weekly champagne plus white wine intake	0.9	1.2	3.7	-0.9	0.5	-1.6	-0.8	-1.9	0.4	-0.8	-0.9
Miserableness	0.5	0.9	2.2	1.4	-0.6	0.6	0.9	1.5	1.0	-0.2	-0.4
Guilty feelings	0.6	0.9	3.3	1.8	-1.0	0.2	0.8	1.4	0.0	0.4	-0.6
Wears glasses or contact lenses	0.8	0.9	3.7	-0.9	0.2	-0.2	-1.9	-0.1	-0.5	-1.3	-0.5
Ever taken oral contraceptive pill	0.7	0.8	2.4	-0.2	0.2	1.0	-0.4	0.7	-0.6	-1.5	-1.3
Hearing aid user	0.6	0.7	1.6	1.3	-0.1	0.7	-0.2	1.3	-1.1	0.3	0.7
Mother’s age at death	0.7	0.8	2.4	-0.4	-1.3	0.3	0.1	1.5	0.7	-0.3	-1.3
Financial situation satisfaction	0.5	0.6	1.7	1.3	-0.0	1.2	0.2	-0.6	0.5	-0.9	-0.4
Tinnitus: Yes, now most or all of the time	0.3	0.4	2.1	1.4	0.1	0.1	0.0	0.8	0.5	-0.2	0.4
Commuting to job workplace: Public transport	0.1	0.1	0.4	-0.5	0.1	-0.6	0.3	-0.1	0.6	0.0	-0.3
Eye problems/disorders: Glaucoma	1.7	2.1	5.2	-2.2	-0.4	0.6	-1.9	-1.4	0.5	-2.3	0.1
Medication: Blood pressure	0.8	1.5	3.2	0.8	0.6	-1.1	1.8	-1.8	1.5	0.3	1.2
Pain type(s) experienced in last month: Hip pain	0.1	0.1	0.3	-0.4	-0.0	0.6	0.1	-0.4	0.1	-0.1	-0.2
Supplements: Fish oil (including cod liver oil)	0.9	1.1	3.4	-1.5	1.8	-0.2	-1.2	-0.7	0.0	-0.8	-0.9
High cholesterol (Self-reported)	1.0	1.7	7.3	0.6	1.0	-0.2	-0.3	-2.7	0.3	-0.0	2.2
Medication: Bendroflumethiazide	0.4	0.7	2.4	0.2	-1.5	-0.0	-0.2	-1.4	0.8	-0.1	0.6
Medication: Paracetamol	0.5	0.8	1.7	-0.4	-1.3	1.0	-0.7	-1.1	0.9	-0.9	0.3
Medication: Lisinopril	0.5	0.7	1.9	1.3	0.1	0.7	0.8	0.1	-1.4	-0.3	0.6
Medication: Atorvastatin	0.3	0.4	1.0	-0.5	-0.6	0.9	-1.0	0.2	-0.8	-0.4	-0.2
Illnesses of father: High blood pressure	0.4	0.5	1.5	1.2	0.7	0.5	0.4	0.7	0.5	0.3	-0.6
Alcohol drinker status: Never	1.1	1.3	2.7	-0.8	1.6	0.5	-1.4	0.4	-0.6	-1.7	-1.4
Ever smoked	0.5	0.9	2.0	1.4	1.3	0.0	1.2	1.0	-0.4	0.6	1.1
Basal metabolic rate	0.2	1.2	3.8	1.5	0.6	0.8	1.2	1.9	0.6	0.8	-0.3
Leg fat percentage (left)	0.2	0.8	2.8	0.2	-1.2	0.3	-0.6	-1.7	1.2	-0.5	-0.2
Arm fat-free mass (left)	0.2	0.8	2.4	1.3	0.4	1.0	0.9	1.5	0.3	0.7	-0.2
Number of operations (self-reported)	0.5	0.7	2.2	1.1	0.7	-0.4	1.5	0.4	0.4	0.9	0.8
Average weekly beer plus cider intake	1.1	1.7	3.2	1.0	-0.4	0.5	1.3	1.5	-1.4	1.8	1.7
Irritability	1.2	2.0	4.6	1.1	-1.2	-0.3	1.7	-0.0	2.0	1.1	2.1
Risk taking	0.5	0.8	1.5	-0.9	0.1	1.0	-1.2	0.8	-0.4	-1.1	-1.0
Ever had prostate specific antigen (PSA) test	1.3	1.4	2.9	1.1	1.3	0.1	1.4	1.7	1.2	0.6	1.3
Fractured/broken bones in last 5 years	0.4	0.6	1.3	0.7	0.4	0.9	0.2	-0.3	1.0	-1.1	0.9
Age started oral contraceptive pill	0.5	0.6	1.5	-1.1	-0.5	-0.2	-1.1	-1.2	-0.7	-0.3	-0.2
Diastolic blood pressure, automated reading	0.3	0.8	2.1	-1.0	1.0	-0.1	0.4	-1.3	0.5	0.4	1.4
Ever depressed for a whole week	0.5	0.6	2.3	-0.2	-0.8	0.6	-0.3	0.5	0.4	-1.0	-1.5
Unable to work because of sickness or disability	0.2	0.3	1.0	0.4	0.8	0.2	-0.3	-0.2	-0.1	-1.0	-0.5
Commuting to job workplace: Cycle	1.2	1.5	3.0	0.3	1.7	-1.5	1.1	0.9	0.6	1.0	-1.7
Myopia	0.5	0.7	2.5	-0.9	-0.9	0.7	-0.4	1.6	-0.2	-0.9	0.1
Vascular/heart problems diagnosed by doctor	0.6	1.5	7.0	-1.3	-1.2	-1.0	-0.9	0.1	-0.1	-0.2	-2.6
Cholesterol lowering medication	1.3	1.9	11.1	0.7	-0.6	-0.3	0.8	-3.3	0.9	0.3	1.4
Medication: Omeprazole (e.g. Zanprol)	0.3	0.4	1.4	0.3	-0.1	-0.4	0.9	-0.1	1.2	0.9	0.2
Pain experienced in last month	0.9	1.5	3.7	1.4	-0.4	-1.7	1.3	0.4	-0.2	1.9	1.3
Supplements: Calcium	0.5	0.5	1.1	-1.0	0.8	-0.9	-0.6	-0.3	0.5	-0.6	-0.6
Basal cell carcinoma (self-reported)	0.8	0.9	3.8	-1.0	-0.1	-0.5	-0.7	-1.9	-1.1	-0.3	0.9
Heart attack/myocardial infarction (self-reported)	1.0	1.3	4.2	-0.4	-0.5	0.9	-2.1	-0.4	-1.4	-1.4	-0.8
Deep venous thrombosis (DVT) (self-reported)	1.2	1.5	6.5	-0.1	-1.4	0.9	0.4	0.6	-2.5	1.1	1.1
Heart disease (siblings)	0.5	0.6	2.7	0.6	-0.9	-0.1	0.4	-0.1	1.6	0.3	0.6
Alcohol drinker status: Previous	0.7	0.7	2.8	1.7	-0.3	0.2	1.2	0.8	0.1	0.2	1.0
Pack years of smoking	1.0	1.5	4.4	0.3	1.8	-1.5	0.3	-2.1	0.4	0.6	-1.1
Impedance of whole body	0.1	0.7	2.8	-1.2	0.6	0.2	-0.8	0.3	-0.5	-1.7	-0.3
Leg fat mass (left)	0.1	0.5	1.7	1.0	-0.5	0.5	0.0	-0.6	1.3	-0.0	-0.1
Arm predicted mass (left)	0.2	1.1	3.6	1.5	0.4	1.6	0.7	1.9	-0.0	0.4	0.1