Hub : Genes

FAM161A

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Artery Tibial 0.1140 0.0469 1.1e-03 0.023 NA 0.052 NA 0.034 6.1e-03 NA 6.7e-05 NA 1.1e-03
2 GTEx Stomach 0.2490 0.0920 3.0e-03 0.002 NA 0.005 NA -0.003 2.4e-01 NA 1.8e-01 NA 4.7e-01
3 GTEx Testis 0.3520 0.0750 3.6e-06 0.191 NA 0.176 NA 0.205 6.7e-09 NA 2.9e-08 NA 1.8e-09
4 GTEx Thyroid 0.1140 0.0460 1.0e-04 0.033 NA 0.058 NA 0.053 1.3e-03 NA 3.1e-05 NA 7.0e-05
5 YFS Blood 0.0207 0.0114 2.3e-02 0.002 0.004 0.008 0.005 0.006 4.7e-02 0.01500 6.7e-04 0.006 4.1e-03
6 TCGA Esophageal Carcinoma 0.3130 0.1320 3.3e-03 -0.009 0.072 0.103 NA 0.001 9.1e-01 0.00270 3.7e-04 NA 2.9e-01
7 TCGA Pancreatic Adenocarcinoma 0.0830 0.0450 4.4e-03 0.000 0.022 0.005 NA 0.013 3.3e-01 0.04000 1.9e-01 NA 8.9e-02
8 TCGA Thyroid Carcinoma 0.0750 0.0370 1.9e-03 0.018 0.028 0.034 NA 0.010 5.9e-03 0.00086 2.9e-04 NA 3.4e-02

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.5 0.8 2.0 1.0 -1.4 0.3 -0.8 -0.5 -1.2 0.3 0.8
Bipolar Disorder or Schizophrenia 0.1 0.1 0.5 0.7 -0.2 0.1 -0.4 -0.2 -0.1 0.1 0.5
Depressed Affect (Nagel 2018) 0.7 1.4 3.5 1.2 -0.8 -1.4 1.3 0.1 1.9 1.5 -0.3
Depression (Nagel 2018) 0.6 0.9 4.5 -0.3 0.1 -1.4 0.1 -0.8 2.1 0.3 -0.5
Intelligence (Savage-Jansen 2018) 0.4 1.2 6.4 0.2 1.0 0.1 0.2 2.5 -0.6 0.1 1.4
Neuroticism (Nagel 2018) 0.6 1.4 3.7 1.0 -1.9 -1.1 1.0 0.7 1.6 1.2 0.4
Schizophrenia (2018) 0.1 0.2 0.5 0.1 0.7 0.0 0.1 0.2 0.6 -0.1 0.6
Schizophrenia vs Biploar Disorder 0.7 0.9 2.8 -0.3 1.5 0.1 0.7 1.7 0.5 -0.4 -0.9
Worry (Nagel 2018) 0.7 1.6 5.6 -0.1 -2.4 -1.2 0.6 0.4 1.7 1.0 1.1
Alzheimer’s Disease (in mother) 0.8 0.9 1.9 1.2 -0.4 -1.4 -0.1 -1.1 0.6 1.0 1.1
Alzheimer’s Disease (in father) 1.0 1.1 2.2 0.0 -1.3 1.5 -1.2 1.4 -0.5 -0.4 0.9
Alzheimer’s Disease (including proxy) 0.7 1.0 2.1 1.0 -1.2 -1.0 -0.7 -0.9 0.7 0.9 1.5
Crohns Disease (2017) 0.3 0.6 3.3 0.0 -1.8 -0.4 -0.1 1.1 -0.0 0.4 -0.7
Irritable Bowel Disease (IBD) 0.9 2.1 6.0 1.3 -2.4 0.2 1.5 2.4 0.6 0.7 0.3
Ulcerative Colitis (UC) 1.5 2.8 8.0 1.3 -2.5 1.2 1.9 2.8 0.3 0.3 1.1
Major Depression (MDD) 0.3 0.3 0.7 -0.3 0.8 -0.1 -0.6 0.6 0.7 -0.3 -0.9
Reaction Time 0.9 1.7 8.0 0.4 0.9 -1.8 0.3 -2.8 0.2 0.2 0.9
Verbal and Numeric Reasoning (VNR) 0.5 1.2 7.7 -0.3 0.6 0.3 -0.8 2.8 -0.9 -0.4 0.1
Breast Cancer 0.5 1.3 4.2 1.4 -0.4 0.4 2.0 0.4 -1.4 1.2 0.3
Ovarian Cancer 0.6 0.8 2.3 1.5 0.1 -0.4 1.4 1.0 -0.5 0.8 0.5
Prostate Cancer 0.4 0.6 2.7 -0.1 -0.9 1.6 -0.0 0.2 -0.1 -0.4 1.1
Age at First Birth 0.9 1.2 6.9 1.5 0.3 0.6 0.5 2.6 -0.3 0.2 0.2
Bipolar Disorder (2011) 0.8 0.8 4.2 0.0 -0.2 -0.8 -0.8 -2.1 -0.3 0.4 0.7
Body Mass Index (BMI) (2010) 0.7 0.9 2.9 -0.5 0.1 -1.0 -0.7 -1.5 0.4 0.2 -1.7
Coronary Artery Disease (CAD) 1.1 1.3 2.9 -0.8 -0.7 -0.5 -1.7 -1.1 1.2 -1.6 -0.5
Crohns Disease (2012) 0.4 0.7 2.4 0.1 -0.0 -1.6 0.7 0.4 1.0 1.3 -0.2
Mean Putamen Volume 1.0 1.1 3.2 -0.8 1.6 -1.1 0.2 -0.8 1.8 0.7 0.4
Fasting Glucose 1.5 1.8 5.5 -0.1 1.0 1.8 -0.5 2.3 -0.7 -2.0 -0.4
HbA1C 1.1 1.2 4.0 1.3 2.0 -0.6 1.9 -0.2 0.2 0.4 -0.1
HDL Cholesterol 0.6 0.9 4.0 1.1 1.1 0.4 -0.0 2.0 0.1 -0.8 -0.3
LDL Cholesterol 0.3 0.5 1.6 -0.1 0.8 -0.6 0.5 0.1 1.1 0.3 -1.3
Lupus 2.2 3.3 6.7 -0.0 1.6 -2.4 2.2 0.4 2.4 2.6 -0.1
Neuroticism (2016) 0.7 1.1 6.3 -0.2 -0.2 -0.6 0.6 0.9 2.5 0.7 -0.1
Primary Biliary Cirrhosis 1.2 1.7 4.0 -0.2 0.2 1.9 -2.0 1.5 0.2 -1.3 -1.5
Rheumatoid Arthritis 1.3 1.7 3.9 -2.0 -0.8 0.8 -1.5 -1.6 -0.4 -1.9 -0.2
Schizophrenia (2014) 0.1 0.2 0.5 0.2 0.5 0.1 -0.3 0.6 0.7 -0.2 0.2
Triglycerides 0.0 0.0 0.1 -0.2 0.2 0.4 0.3 -0.0 0.0 -0.1 -0.3
Type 2 Diabetes (T2D) (2012) 0.7 0.8 1.8 -0.7 -0.6 1.2 -0.7 1.0 -1.3 -0.9 -0.2
Ulcerative Colitis 2.8 4.1 10.3 2.3 -1.1 0.0 3.2 3.2 0.9 1.8 1.2
Blood Eosinophil Count 0.4 2.9 7.8 -2.0 1.8 -0.9 -2.0 -2.8 -0.8 -1.4 -0.6
Blood Platelet Count 0.1 1.6 10.0 -0.8 3.2 -1.0 -0.4 -0.3 -0.2 -1.0 -0.2
Blood Red Count 1.6 15.5 44.7 -2.9 -1.5 -0.2 -6.7 -1.9 1.3 -5.2 -6.1
Blood White Count 0.9 6.5 19.8 -2.1 3.8 -3.1 -1.1 -4.5 -1.3 0.1 -0.4
Heel T-Score 0.3 2.2 5.8 -1.8 -0.5 1.8 -1.8 0.5 1.0 -2.4 -0.8
BMI 0.4 2.4 7.0 2.0 0.1 -1.4 1.3 -1.0 2.6 1.7 -0.4
Height 0.2 2.9 14.2 1.1 0.9 0.2 1.6 3.8 -1.6 1.3 -0.8
Waist Hip Ratio (WHR) 0.2 1.1 2.2 1.1 0.0 -0.8 1.4 -0.1 -0.8 1.4 1.5
Systolic Blood Pressure 0.3 1.5 4.4 1.6 1.4 1.2 1.2 0.2 -0.1 -0.1 2.1
Smoking Status 0.7 1.7 4.3 0.6 2.1 -1.5 0.6 -1.2 -2.1 0.7 0.4
Allergy or Eczema 0.3 0.7 2.7 0.5 -0.8 -0.3 0.7 1.6 0.6 1.2 0.3
Cardiovascular Disease 1.2 4.0 10.4 2.3 2.3 -1.0 1.9 -1.7 0.9 1.7 3.2
Hypothyroidism (self reported) 0.4 0.8 1.8 0.0 -1.3 -0.5 1.4 0.8 0.4 1.1 -0.9
Respiratory disease 0.3 0.7 1.5 -0.4 -1.2 -0.1 0.5 0.1 1.1 1.2 1.1
Type 2 Diabetes (T2D) (2018) 0.5 0.9 3.5 -0.8 0.2 -0.4 -1.2 -0.9 -0.1 -1.0 -1.9
Lung FEV1/FVC ratio 0.7 3.6 9.6 -0.9 -3.1 1.2 -1.4 2.0 2.3 -1.4 -2.0
Lung FVC 0.3 1.5 3.0 -1.1 0.7 0.4 -1.3 -1.7 -1.0 -1.4 -1.7
Neuroticism 0.8 2.0 6.5 0.5 -2.3 -1.3 0.9 -0.5 2.5 1.1 0.6
Chronotype (morning person) 1.0 2.3 10.7 -1.1 -1.4 -1.0 -1.0 0.8 -1.2 -0.4 -3.3
Hair Pigment 0.2 5.4 15.8 4.0 1.0 -1.5 3.7 -0.0 1.0 2.4 1.9
Tanning 0.1 0.7 1.8 1.0 -0.8 1.1 0.1 1.3 -1.0 0.5 -0.4
Hand grip strength (left) 0.9 2.4 6.2 2.5 0.9 -0.1 1.9 1.9 -0.9 1.9 -0.7
Number of treatments/medications taken 0.8 1.4 3.7 -1.9 -1.3 0.4 -0.4 -1.6 1.6 -0.2 0.5
Average weekly spirits intake 0.8 1.0 4.9 2.2 0.4 0.5 1.0 0.2 0.3 -0.3 1.0
Sensitivity / hurt feelings 0.7 1.2 3.9 1.6 -1.3 1.2 0.4 0.2 0.3 0.1 2.0
Frequency of depressed mood in last 2 weeks 2.5 3.5 13.1 0.5 1.2 -2.6 1.9 -0.7 3.6 1.6 -0.4
Hearing difficulty/problems: Yes 0.6 1.0 4.3 0.4 -0.8 0.1 0.8 -0.4 0.0 1.4 2.1
Relative age of first facial hair 0.1 0.2 0.5 0.7 -0.5 0.0 -0.2 0.7 -0.0 0.2 -0.3
Other serious medical condition/disability diagnosed by doctor 1.3 1.7 6.1 0.3 -0.3 0.9 0.7 2.5 2.4 -0.3 -0.7
Ever used hormone-replacement therapy (HRT) 0.9 1.1 2.6 0.4 0.6 1.6 -0.7 1.6 -0.3 -1.3 0.7
Ever had hysterectomy (womb removed) 1.0 1.2 6.6 1.0 -0.8 1.0 0.2 -0.4 0.1 -0.0 2.6
Systolic blood pressure, automated reading 0.6 1.6 8.1 0.8 0.2 0.3 1.4 -0.4 0.6 1.3 2.8
Eye problems/disorders: Diabetes related eye disease 0.6 0.6 1.6 0.6 1.1 0.2 0.4 1.3 -0.8 -0.8 -0.2
Angina 0.3 0.4 1.5 0.3 -0.3 0.9 -1.2 -0.1 -0.5 -0.6 0.1
Medication for hormone replacement therapy 2.1 2.4 5.4 -0.6 -0.9 2.3 -1.9 1.8 0.2 -2.2 -0.9
Vitamin and mineral supplements 1.3 1.7 7.0 1.7 0.7 1.0 0.6 2.6 -0.6 0.2 1.3
Supplements: Zinc 0.2 0.2 0.5 0.7 0.5 -0.2 0.7 0.4 0.2 0.5 0.3
Medication: Co-codamol 2.3 2.6 5.3 1.6 1.3 -1.3 2.3 -0.7 1.9 1.6 1.6
Medication: Metformin 0.9 1.2 2.8 -1.1 -0.7 0.4 -1.7 -0.7 -0.5 -1.3 -1.6
Diabetes (father) 1.5 1.8 7.5 0.5 0.5 -1.7 1.2 -0.1 2.7 0.9 -1.2
Diabetes (mother) 0.7 0.9 3.7 0.4 0.3 -0.9 0.9 -0.6 1.9 1.1 -0.0
Severe depression (siblings) 0.4 0.5 1.2 -0.9 0.6 -1.1 -0.6 -0.7 0.5 0.2 0.5
Pack years adult smoking proportion 1.1 1.7 4.6 0.5 2.1 -1.6 0.4 -2.0 0.7 0.6 -0.9
Impedance of leg (right) 0.2 0.8 2.0 -1.3 -0.2 0.3 -1.1 -0.5 -0.8 -1.4 -0.6
Leg fat-free mass (left) 0.3 1.5 3.3 1.6 1.0 0.3 1.7 1.8 0.9 1.1 0.4
Trunk fat percentage 0.1 0.5 2.1 0.7 0.3 0.3 0.4 -0.7 1.5 -0.1 0.7
Hand grip strength (right) 0.4 1.0 4.8 0.2 1.4 -0.4 -0.3 0.6 -0.6 0.2 -2.2
Townsend deprivation index at recruitment 0.3 0.4 1.8 -0.3 0.5 -0.8 -0.0 -0.6 -0.1 0.3 1.4
Current tobacco smoking 0.8 1.3 6.9 0.2 0.8 -1.4 0.0 -2.6 0.2 0.4 0.6
Average weekly fortified wine intake 0.6 0.6 1.8 -1.1 -0.6 -0.2 -0.6 -1.3 -0.1 -0.5 1.1
Maternal smoking around birth 1.2 1.7 5.9 -2.4 0.8 -0.9 -1.5 -1.9 -0.1 -0.7 0.2
Fed-up feelings 0.8 1.5 6.2 0.3 -0.7 -1.4 0.9 -1.0 2.5 1.0 -0.7
Frequency of unenthusiasm / disinterest in last 2 weeks 0.4 0.5 3.4 0.1 0.3 0.2 0.3 -0.2 1.8 -0.3 0.5
Relative age voice broke 0.2 0.2 0.5 -0.2 0.4 -0.1 -0.7 -0.5 0.1 -0.7 -0.7
Taking other prescription medications 0.8 1.2 2.9 -1.6 -0.8 -0.7 -0.0 -1.5 1.7 0.5 -0.7
Age when periods started (menarche) 1.3 3.2 9.3 -1.5 -0.0 0.9 -2.9 -1.4 -0.8 -3.1 -1.5
Bilateral oophorectomy (both ovaries removed) 2.0 2.3 4.4 1.9 0.0 0.5 1.5 2.1 1.5 1.2 2.1
Heel bone mineral density (BMD) T-score, automated (left) 0.5 1.1 2.2 -1.0 1.4 0.4 -1.3 0.8 0.0 -0.9 -1.5
Tinnitus: Yes, but not now, but have in the past 0.6 0.6 2.3 -0.2 -1.1 -0.6 -0.5 -1.5 -0.7 0.5 0.4
Qualifications: CSEs or equivalent 1.0 1.3 3.2 1.4 0.2 -0.3 1.6 0.8 1.3 0.1 -1.8
Serious illness, injury or assault to yourself 1.4 1.8 4.3 -2.0 -1.0 -0.9 -1.5 -2.1 0.1 -0.3 -1.2
High blood pressure 0.7 2.0 9.4 1.4 1.1 1.1 1.2 0.3 0.1 0.5 3.1
Hayfever, allergic rhinitis or eczema 0.6 1.3 2.7 0.5 -1.3 -0.4 1.2 1.6 1.6 1.3 -0.5
Multivitamins +/- minerals 1.5 2.0 8.1 -1.7 -0.7 -0.9 -0.7 -2.8 1.6 -0.4 0.4
Stomach or abdominal pain in last month 0.2 0.3 0.7 0.4 0.5 0.8 -0.2 0.2 -0.5 -0.8 -0.5
Supplements: Glucosamine 0.7 1.0 4.1 0.0 2.0 0.9 -0.3 -0.2 -0.8 -0.1 1.4
Diverticular disease/diverticulitis (self-reported) 0.6 0.7 2.7 1.6 1.1 0.2 0.8 0.5 0.8 -0.3 0.7
Medication: Atenolol 0.7 0.9 2.6 1.4 0.6 1.6 -0.2 0.2 -1.0 -0.9 0.8
Medication: Levothyroxine sodium 0.3 0.5 2.0 -0.4 -0.6 0.3 0.9 -0.5 1.4 -0.1 0.5
Sitting height 0.3 2.1 9.5 0.9 1.4 0.4 1.4 3.1 -0.4 0.3 -1.4
Chronic bronchitis/emphysema (father) 1.3 1.5 5.0 -0.3 -2.2 1.2 -0.3 -1.1 -0.2 -0.1 2.1
High blood pressure (mother) 0.5 0.6 2.6 -1.2 0.5 0.4 0.6 -0.2 1.6 -0.2 0.4
Body mass index (BMI) 0.2 0.9 3.2 0.9 -1.1 0.3 0.2 -1.2 1.8 0.4 0.5
Impedance of leg (left) 0.3 1.3 3.3 -1.3 -0.0 0.8 -1.6 -0.3 -1.1 -1.8 -1.0
Leg predicted mass (left) 0.3 1.4 3.5 1.6 1.0 0.4 1.6 1.9 0.8 1.0 0.3
Trunk fat mass 0.1 0.5 2.0 1.1 0.4 0.2 0.7 -0.1 1.4 0.3 0.2
Waist circumference 0.1 0.4 2.2 0.5 -0.2 -0.1 0.2 -0.9 1.5 0.3 0.3
Number of incorrect matches in round 1.7 2.8 9.7 -1.8 -1.2 -1.1 -0.9 -3.1 -1.0 1.9 1.0
Past tobacco smoking 0.5 0.9 2.0 -1.0 -0.9 0.1 -1.3 -0.6 1.1 -0.7 -1.4
Alcohol usually taken with meals 1.6 2.6 7.0 -1.3 1.7 -0.5 -1.9 0.2 0.4 -2.6 -2.3
Nervous feelings 0.9 1.6 4.1 1.2 -0.6 -1.2 1.8 0.4 2.0 1.1 0.8
Frequency of tenseness / restlessness in last 2 weeks 1.9 3.0 8.0 0.8 2.1 -2.4 1.8 -0.6 2.8 1.2 -0.2
Hearing difficulty/problems with background noise 0.5 0.8 1.6 1.3 -1.1 0.1 0.9 0.6 -1.0 1.1 -0.1
Hair/balding pattern: Pattern 2 1.2 1.6 3.4 -1.8 -0.8 0.9 -1.2 -1.0 -1.7 -1.3 -0.8
Had menopause 0.3 0.4 1.7 -0.5 -0.0 -1.3 0.2 -0.4 0.7 0.7 0.5
Had other major operations 0.3 0.4 1.5 1.2 0.0 -0.2 0.6 -0.3 0.0 -0.2 1.1
Forced vital capacity (FVC) 0.5 1.9 3.8 0.1 1.9 1.4 -0.4 1.1 -1.9 -1.6 -1.4
Heel bone mineral density (BMD) T-score, automated (right) 0.6 1.3 4.0 -0.2 0.8 2.0 -0.8 1.7 0.6 -1.3 -0.3
Ever unenthusiastic/disinterested for a whole week 1.1 1.4 4.2 -1.4 0.1 0.3 -0.8 -0.6 2.0 -1.4 -1.3
Qualifications: None of the above 0.4 0.9 3.0 1.0 0.9 -0.6 0.2 -1.7 -0.2 1.1 1.0
Financial difficulties in last 2 years 0.6 0.8 4.3 -0.2 -0.9 0.4 0.6 0.5 2.1 0.2 0.2
Mouth/teeth dental problems 0.1 0.2 0.4 -0.1 0.6 0.1 0.5 0.2 -0.2 0.5 0.5
Heart attack 0.7 0.9 3.1 -0.2 -0.2 0.9 -1.8 -0.3 -1.3 -1.2 -0.4
Allergy 0.6 1.3 3.6 0.4 1.9 0.3 -1.3 -1.4 -0.6 -1.5 -0.4
Pain all over the body in last month 2.4 2.6 5.8 -2.3 0.1 0.1 -2.4 -1.7 1.1 -1.8 -1.3
Diabetes (self-reported) 0.8 1.2 4.0 -0.8 -0.8 -0.5 -1.3 -0.8 0.9 -1.0 -2.0
Hayfever/allergic rhinitis (self-reported) 1.0 1.3 3.7 1.4 0.4 0.3 1.4 1.3 1.9 0.6 0.6
Medication: Ramipril 1.2 1.5 9.1 1.1 3.0 -0.2 0.2 1.2 -0.1 0.5 0.4
Medication: Simvastatin 0.8 1.2 3.9 -0.7 -0.2 0.7 -1.4 -2.0 0.2 -1.5 0.5
Fluid intelligence score 0.6 1.2 8.2 -0.4 0.7 -0.1 -0.4 2.9 0.3 -0.4 -0.0
Illnesses of siblings 0.5 0.7 1.5 -0.6 -1.2 -0.6 -0.5 0.4 -1.2 -0.7 -1.0
Neuroticism score 1.1 2.2 4.8 1.9 -1.9 -0.4 1.6 0.9 2.2 1.2 0.7
Weight 0.1 0.7 1.7 1.3 -0.0 0.4 0.9 0.8 1.3 0.6 -0.1
Impedance of arm (right) 0.2 0.7 2.2 -0.8 1.4 -0.6 0.2 0.2 0.8 -1.5 0.3
Arm fat percentage (right) 0.3 1.0 5.2 1.0 -0.0 -0.1 0.6 -1.0 2.3 -0.1 1.0
Trunk fat-free mass 0.2 1.4 5.8 1.4 0.6 0.7 1.0 2.4 0.1 0.9 -0.9
Hip circumference 0.1 0.4 2.2 0.4 -0.3 0.5 -0.1 0.0 1.5 -0.3 -0.5
Time employed in main current job 0.8 0.9 2.7 1.0 -0.0 -0.7 1.1 -0.4 -0.1 1.6 1.4
Alcohol intake versus 10 years previously 0.7 1.1 2.4 -0.9 -0.1 1.4 -1.2 0.2 1.6 -1.4 0.3
Father’s age at death 1.5 2.0 8.2 -1.8 -2.9 1.0 -0.8 1.2 -0.7 -0.6 -0.8
Worrier / anxious feelings 0.5 0.9 4.6 0.1 -2.1 -0.5 0.4 0.4 0.8 0.7 0.8
Frequency of tiredness / lethargy in last 2 weeks 1.3 2.1 10.5 0.7 1.9 -0.0 1.1 0.9 3.2 -0.3 -0.1
Falls in the last year 0.4 0.6 1.9 -0.5 0.6 0.5 -0.8 -0.0 -0.2 -1.1 -1.4
Hair/balding pattern: Pattern 3 1.5 2.3 4.8 2.1 2.2 -1.4 0.9 2.1 0.7 1.1 -0.2
Number of live births 0.3 0.4 1.2 -0.6 0.4 1.1 -0.7 -0.2 -0.7 -0.9 -0.4
Forced expiratory volume in 1-second (FEV1) 0.7 2.4 5.2 0.5 1.0 1.8 -0.7 2.2 -1.0 -1.8 -2.3
Pulse rate 0.8 1.3 7.1 -1.2 0.5 -1.1 0.0 -0.5 2.7 -0.5 -0.2
Happiness 1.4 1.7 5.4 -1.2 1.2 -1.1 -0.4 0.3 1.9 -0.6 -2.3
Noisy workplace 1.4 1.8 4.7 -0.9 2.2 -0.4 -1.6 -1.9 -0.9 -1.3 -0.2
Qualifications: A levels/AS levels or equivalent 0.6 1.4 6.3 0.0 1.0 0.2 -0.8 2.5 -1.1 -1.2 -1.0
Serious illness, injury or assault of a close relative in last 2 years 0.4 0.5 1.9 -0.8 0.2 0.0 -0.8 -0.7 -1.4 -0.4 -0.0
Mouth/teeth dental problems: Dentures 0.4 0.7 1.9 0.5 0.9 -1.3 0.5 -0.3 -0.1 1.4 0.5
Asthma 0.5 1.0 4.1 -2.0 -1.2 -0.9 -0.7 -0.7 0.5 0.1 -0.5
Medication: Ibuprofen (e.g. Nurofen) 0.4 0.5 2.0 0.6 -0.2 0.9 1.4 0.3 1.0 0.1 0.4
Medication: Cholesterol lowering 0.2 0.3 1.5 -0.3 0.8 -0.2 -1.2 0.1 -0.3 -0.5 -0.4
Depression (self-reported) 0.9 1.1 4.9 0.4 -2.2 -0.0 0.9 -0.6 1.4 0.4 0.5
Medication: Lansoprazole 1.3 1.5 6.2 -2.5 -0.3 -0.7 -1.4 -1.4 -0.8 -0.5 -0.6
Prospective memory result 0.3 0.3 0.8 -0.7 -0.5 -0.9 0.2 -0.4 -0.2 0.7 -0.6
Lung cancer (father) 0.6 0.7 2.1 -0.0 1.2 0.9 -1.1 0.6 -0.3 -1.4 0.1
Illnesses of mother 0.5 0.7 2.3 1.5 1.1 0.6 0.5 0.9 -0.3 -0.1 0.2
Forced expiratory volume in 1-second (FEV1), Best measure 0.4 1.4 3.8 0.4 0.6 1.1 -0.4 2.0 -0.8 -1.1 -1.9
Pulse wave Arterial Stiffness index 0.8 1.0 2.6 0.3 -0.4 -0.0 -1.3 -0.7 1.6 -0.8 1.4
Impedance of arm (left) 0.1 0.6 1.7 -1.3 0.8 -0.5 -0.2 0.5 -0.1 -1.3 -0.3
Arm fat mass (right) 0.2 0.9 4.0 1.2 -0.1 -0.1 0.9 -0.5 2.0 0.6 0.7
Trunk predicted mass 0.2 1.4 6.0 1.4 0.5 0.7 1.0 2.4 0.0 0.9 -1.0
Standing height 0.3 3.4 16.9 1.2 1.9 0.3 1.6 4.1 -0.6 0.8 -1.0
Length of working week for main job 1.1 1.2 5.7 -1.3 0.2 -1.2 -0.5 0.1 0.8 0.1 -2.4
Exposure to tobacco smoke at home 0.6 0.7 2.3 -0.5 -0.5 -0.9 -0.9 -0.8 0.3 0.0 -1.5
Breastfed as a baby 1.9 2.4 6.1 2.5 -0.2 -1.1 2.2 0.7 0.6 2.2 1.0
Tense / ‘highly strung’ 1.3 2.2 5.5 0.7 -1.1 -1.2 1.4 -0.1 2.3 1.8 1.8
Seen doctor (GP) for nerves, anxiety, tension or depression 1.3 1.9 10.0 1.2 -0.2 0.2 1.3 1.5 3.2 -0.3 -0.4
Hair/balding pattern: Pattern 4 1.5 3.6 14.2 -1.8 -0.9 -1.5 -2.1 -3.8 0.3 -1.1 -1.6
Birth weight of first child 0.9 1.6 6.2 -1.7 -0.1 0.1 -1.3 0.9 0.9 -0.8 -2.5
Peak expiratory flow (PEF) 0.8 1.8 8.9 0.6 0.1 0.6 0.2 3.0 0.1 0.0 -2.2
Pulse wave reflection index 0.5 0.6 2.3 1.0 -0.2 1.1 -0.4 -0.2 0.1 -0.4 1.5
Ever highly irritable/argumentative for 2 days 1.4 1.7 11.0 0.8 -0.7 0.6 0.7 0.2 3.3 -0.4 0.8
Loud music exposure frequency 0.7 0.8 1.8 0.7 0.5 -0.7 1.3 0.7 0.2 1.3 1.0
Qualifications: O levels/GCSEs or equivalent 1.3 2.1 11.0 0.0 -0.0 1.6 0.0 3.3 -0.9 -1.0 -1.1
Mouth/teeth dental problems: Bleeding gums 0.4 0.5 1.9 -0.2 -0.6 1.4 -0.3 0.6 0.2 -1.1 0.3
Blood clot in the leg (DVT) 1.3 1.7 8.9 -0.4 -1.3 1.2 -0.0 0.4 -3.0 0.7 1.0
Medication: Paracetamol 0.4 0.6 1.8 -0.5 -0.8 0.8 -0.7 -1.4 0.8 -0.7 -0.0
Headache pain in last month 1.1 1.8 6.8 -1.0 0.6 0.9 -1.8 -0.7 1.1 -2.6 -1.1
Medication for cholesterol, blood pressure or diabetes 0.3 0.5 1.7 -0.2 -0.6 -0.5 1.3 0.3 1.0 0.4 0.2
Glaucoma (self-reported) 2.6 3.0 8.8 -3.0 -0.5 -1.6 -1.3 -2.5 2.0 -0.8 0.1
Gout (self-reported) 0.8 1.0 4.3 -0.1 0.8 -0.5 0.8 -0.3 -0.9 1.1 2.1
Hypothyroidism/myxoedema (self-reported) 0.2 0.4 1.2 0.1 -0.4 0.2 1.1 0.9 1.0 0.5 -0.4
Medication: Amlodipine 0.6 0.8 5.6 -0.3 -0.2 -0.6 0.0 -2.4 -0.6 -0.2 0.3
Medication: Ventolin 100micrograms inhaler 1.6 2.0 4.3 -1.8 -2.1 1.0 -1.9 -0.4 -0.3 -1.7 -0.9
Birth weight 0.4 0.8 4.0 0.2 1.1 -0.8 0.4 0.7 0.2 -0.1 -2.0
Chronic bronchitis/emphysema (mother) 0.4 0.4 1.3 -0.5 1.1 -0.4 -0.0 -0.0 1.1 -0.2 -0.8
High blood pressure (siblings) 0.3 0.4 1.4 0.3 1.2 0.8 -0.2 -0.3 -0.4 0.1 1.0
Forced vital capacity (FVC), Best measure 0.3 0.9 2.0 -0.2 1.4 0.9 -0.5 0.8 -1.4 -1.0 -0.9
Body fat percentage 0.1 0.5 2.1 0.6 -0.2 0.1 -0.0 -1.0 1.4 -0.3 0.4
Leg fat percentage (right) 0.2 0.8 2.6 0.2 -1.2 -0.1 -0.3 -1.6 1.4 -0.2 -0.0
Arm fat-free mass (right) 0.2 0.8 3.3 1.1 0.2 1.2 0.4 1.8 -0.2 0.7 -0.5
Exposure to tobacco smoke outside home 0.8 1.1 2.9 -0.1 0.9 -1.2 -0.5 -1.7 1.7 -0.7 -0.4
Comparative body size at age 10 0.3 0.9 2.6 -1.6 -1.3 1.1 -0.5 -1.0 -0.4 -0.4 0.6
Number of full brothers 0.2 0.2 0.7 0.2 0.7 0.3 0.2 0.5 -0.8 -0.5 0.3
Worry too long after embarrassment 0.7 1.2 3.2 1.1 -0.9 0.5 1.3 1.8 0.4 0.9 1.0
Seen a psychiatrist for nerves, anxiety, tension or depression 1.5 2.0 6.1 0.1 -1.7 -1.2 -0.2 -0.3 2.3 0.0 -2.5
Wheeze or whistling in the chest in last year 0.4 0.8 3.4 -0.5 0.7 -0.5 -0.5 -1.9 1.1 -0.3 -0.2
Number of children fathered 0.4 0.5 1.5 0.6 -0.3 0.5 -0.2 1.2 -0.5 0.1 -1.2
Reason for reducing amount of alcohol drunk: Health precaution 0.4 0.5 1.3 0.4 -0.2 0.5 0.5 1.0 -1.2 0.8 -0.1
Age at first live birth 0.7 1.2 5.1 -1.1 0.4 -0.7 -0.5 1.6 0.2 -0.3 -2.2
Pulse wave peak to peak time 0.9 1.0 2.2 -0.2 0.4 0.2 1.5 1.1 -1.4 0.9 -1.3
Health satisfaction 0.7 0.9 3.1 0.4 1.5 0.7 0.5 0.6 1.8 -0.3 0.4
Shortness of breath walking on level ground 1.3 1.6 4.4 -1.4 0.1 -0.1 -1.2 -2.1 0.3 -1.4 -1.7
Qualifications: College or University degree 0.6 2.0 5.9 -1.7 -0.6 -0.3 -1.9 0.8 -0.0 -1.5 -2.4
Eye problems/disorders: None of the above 0.5 0.6 1.6 1.1 -0.5 1.3 0.9 1.0 0.0 0.3 -0.1
Mouth/teeth dental problems: Loose teeth 0.7 0.9 2.0 -0.1 -0.1 -1.1 0.4 -1.4 1.4 0.5 1.2
Emphysema/chronic bronchitis 0.4 0.5 1.5 0.3 -1.0 0.2 0.6 -0.3 0.8 0.3 1.2
Medication for pain relief, constipation, heartburn 0.2 0.3 0.8 0.5 0.0 -0.6 -0.0 0.2 -0.6 0.6 0.9
Neck or shoulder pain in last month 0.5 0.8 3.2 -0.3 1.2 -0.3 0.3 -1.8 0.3 -0.6 0.9
Medication: Blood pressure 0.5 0.9 3.3 0.6 -0.1 1.8 -0.9 0.7 -1.4 -0.7 0.3
Angina (self-reported) 0.2 0.3 1.2 0.3 -0.2 0.8 -1.1 -0.4 -0.2 -0.6 0.4
Migraine (self-reported) 0.6 0.7 2.0 -0.7 0.3 1.3 -0.3 -0.6 -0.5 -1.4 0.7
Medication: Ibuprofen 0.8 0.9 2.1 1.0 -0.4 1.3 1.4 0.8 1.2 -0.3 0.5
Medication: Allopurinol 0.7 1.0 3.2 -0.1 0.5 -1.8 0.7 -1.1 -0.7 1.3 0.7
Medication: Omeprazole 1.0 1.2 3.0 1.0 -0.1 -0.7 1.7 0.2 1.6 1.6 0.5
Medication: Seretide 50 evohaler 1.3 1.5 4.0 -2.0 -1.5 -0.4 -0.9 -1.6 0.8 -1.0 -0.5
Mean time to correctly identify matches 0.8 1.6 6.4 0.7 0.3 -1.6 0.1 -2.5 -0.4 0.5 1.6
Heart disease (mother) 1.9 2.4 4.8 -1.9 -2.2 -0.3 -2.0 -1.8 -1.3 -0.9 -0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.6 0.7 2.0 -0.3 1.3 -0.6 0.7 0.5 -0.2 0.5 -1.4
Whole body fat mass 0.1 0.5 2.3 0.9 -0.2 0.1 0.4 -0.6 1.5 0.2 0.3
Leg fat mass (right) 0.1 0.4 1.8 0.9 -0.5 0.3 0.2 -0.6 1.3 0.1 -0.1
Arm predicted mass (right) 0.2 0.8 2.9 1.2 0.3 0.9 0.6 1.7 -0.2 0.8 -0.5
Pulse rate, automated reading 0.3 0.8 3.2 -0.7 -0.9 -0.1 0.1 -0.9 1.8 -0.5 -1.0
Alcohol intake frequency. 0.2 0.6 1.8 0.1 -1.2 -0.4 -0.7 -0.3 0.8 -0.0 -1.4
Comparative height size at age 10 0.2 1.2 3.3 0.5 -0.3 0.9 1.5 1.8 -0.7 1.3 0.8
Number of full sisters 0.9 1.1 4.7 -0.2 -2.2 -0.0 -0.6 -1.3 0.9 -0.0 -1.2
Suffer from ‘nerves’ 0.5 0.7 2.2 1.3 -0.5 0.6 0.6 1.5 0.8 -0.4 0.2
Overall health rating 0.7 1.4 3.0 0.8 1.2 -1.3 1.3 -0.7 1.7 1.4 0.6
Chest pain or discomfort 0.6 0.8 1.5 -1.2 0.1 0.6 -1.2 -0.7 1.2 -1.0 0.4
Had major operations 0.9 1.1 2.2 -1.4 0.2 -0.3 -1.1 -1.3 0.4 -1.0 -1.5
Age at last live birth 1.7 2.4 4.1 -2.0 -2.0 0.7 -1.9 0.2 -1.3 -1.2 -1.9
Family relationship satisfaction 1.7 2.0 8.5 -1.1 -0.4 -0.7 -1.9 0.5 0.7 -1.3 -2.9
Leg pain on walking 0.7 0.9 4.6 1.1 0.2 0.5 0.9 0.5 2.1 0.1 0.0
Qualifications: NVQ or HND or HNC or equivalent 1.4 1.6 6.7 -0.5 0.5 1.7 -1.0 -0.0 1.4 -2.6 -0.4
Commuting to job workplace: Car/motor vehicle 0.3 0.3 0.9 0.4 -0.3 1.0 -0.1 -0.3 -0.4 -0.7 0.7
Illness, injury, bereavement, stress in last 2 years 0.1 0.1 0.3 0.5 0.6 -0.2 0.2 -0.2 -0.5 -0.1 0.1
Medication: Aspirin 0.6 0.8 1.8 -0.0 1.1 0.4 -0.5 1.4 -1.2 -1.0 -0.5
Supplements: Vitamin C 2.1 2.5 5.1 2.2 0.8 -0.8 1.4 2.1 -0.9 0.9 -2.3
Knee pain experienced in last month 1.2 1.8 4.1 -1.4 0.0 0.7 -2.0 -1.8 0.3 -1.7 -1.3
Hypertension (Self-reported) 0.7 1.9 8.7 1.6 0.9 0.9 1.2 0.1 0.7 0.5 2.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.7 0.8 4.1 -0.8 -0.8 -0.0 0.5 -0.8 2.0 0.3 0.3
Illnesses of father: Heart disease 0.3 0.4 1.3 0.5 1.1 0.0 -0.5 0.6 -0.6 -0.1 -0.7
Illnesses of siblings: Diabetes 0.4 0.5 1.6 -0.7 -0.3 -0.6 0.0 -1.0 0.4 1.2 -0.7
Smoking status: Previous 0.4 0.7 2.6 0.3 0.7 -0.1 0.8 0.5 -1.6 0.4 1.1
Forced expiratory volume in 1-second (FEV1), predicted 0.8 1.7 4.4 0.6 1.6 -1.5 1.5 1.3 0.6 2.1 -0.0
Whole body fat-free mass 0.2 1.3 4.7 1.5 0.8 0.6 1.2 2.2 0.4 1.0 -0.4
Leg fat-free mass (right) 0.3 1.5 4.1 1.5 1.1 0.5 1.5 2.0 0.8 1.0 0.2
Arm fat percentage (left) 0.2 0.7 3.7 0.7 -0.2 -0.1 0.4 -0.7 1.9 -0.1 0.6
Average weekly red wine intake 0.2 0.4 0.9 0.4 1.0 0.0 -0.8 0.6 -0.0 -0.8 -0.1
Handedness (chirality/laterality): Left-handed 0.7 0.8 2.9 1.2 0.3 -0.5 1.7 1.0 -0.4 0.5 -0.7
Mood swings 1.5 2.6 9.0 1.5 -0.6 -1.6 2.1 -0.4 3.0 1.5 0.3
Loneliness, isolation 0.8 1.2 3.2 0.2 -1.8 -0.5 -0.2 -1.6 0.6 0.2 -1.7
Long-standing illness, disability or infirmity 0.6 0.9 4.2 -2.0 -0.3 1.1 -0.9 -0.2 0.6 -0.9 0.1
Ever had bowel cancer screening 0.2 0.2 0.8 -0.2 -0.4 -0.1 -0.4 0.1 -0.9 0.2 -0.6
Diabetes diagnosed by doctor 1.0 1.7 7.0 -0.4 -0.8 -0.4 -1.5 -0.9 0.8 -1.3 -2.6
Ever had stillbirth, spontaneous miscarriage or termination 0.6 0.7 1.8 1.3 -1.2 0.6 0.5 1.3 -0.2 0.2 0.2
Friendships satisfaction 3.4 4.3 16.2 -1.1 0.6 0.8 -2.5 1.0 0.8 -2.8 -4.0
Qualifications: nursing, teaching 0.7 1.0 4.7 -0.5 0.6 -0.3 -0.6 1.2 -0.3 -1.0 -2.2
Commuting to job workplace: Walk 0.5 0.6 1.4 -0.4 -0.6 0.1 -1.1 -1.0 -0.7 -1.2 -0.2
Eye problems/disorders: Cataract 0.4 0.4 2.2 0.0 -0.2 -0.1 -0.7 -1.5 0.7 -0.4 0.2
Mouth/teeth dental problems: Mouth ulcers 0.4 0.6 2.2 -0.5 -0.3 0.5 -1.2 0.0 -0.5 -1.5 -0.8
Medication for cholesterol 0.8 1.3 3.1 -0.8 0.5 -0.9 -0.4 1.5 -1.4 0.9 -1.8
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.4 0.5 2.2 -1.5 -0.9 -0.2 0.1 -0.8 -0.1 0.6 -0.5
Back pain experienced in last month 0.8 1.2 3.7 0.3 -0.5 1.9 0.6 -0.6 -1.5 0.5 1.4
Mineral and other dietary supplements 0.4 0.5 1.2 1.1 -1.1 0.1 0.5 0.8 -0.3 0.6 0.5
Breast cancer (self-reported) 0.4 0.5 1.4 -0.4 0.7 -1.2 0.4 -0.2 0.8 1.0 0.2
Asthma (self-reported) 0.4 0.8 3.9 -2.0 -1.1 -0.4 -0.8 -0.4 0.6 -0.1 -0.3
Osteoporosis (self-reported) 1.0 1.2 6.0 -0.6 -0.9 -0.9 -0.4 -2.4 1.2 0.0 0.5
Osteoarthritis (self-reported) 0.7 0.9 3.5 -1.9 -0.1 0.2 -1.1 -1.2 -0.5 0.0 0.8
Medication: Aspirin 0.7 0.8 2.9 -0.1 1.7 0.3 -0.6 1.0 -1.3 -0.9 -0.3
Medication: Gliclazide 3.4 3.9 11.5 -1.4 -3.3 0.4 -1.7 -1.5 -0.0 -1.0 -3.4
Illnesses of father: None of the above (group 1) 1.5 1.8 4.3 -1.3 1.0 -2.1 -0.2 -2.0 0.4 -0.2 -1.8
Smoking status: Current 0.6 0.9 4.8 0.2 0.8 -1.1 0.1 -2.2 0.3 0.3 0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.7 1.5 4.3 -0.7 -0.0 0.7 -1.7 0.0 -0.9 -2.1 -1.8
Whole body water mass 0.2 1.4 4.9 1.5 0.8 0.7 1.3 2.2 0.4 0.9 -0.3
Leg predicted mass (right) 0.3 1.4 4.0 1.5 1.0 0.5 1.4 2.0 0.7 0.9 0.1
Arm fat mass (left) 0.1 0.6 2.7 0.9 -0.5 0.3 0.4 -0.5 1.6 0.2 0.3
Number of self-reported non-cancer illnesses 0.9 1.5 6.5 -0.2 -0.8 0.4 0.7 -0.4 2.5 0.5 1.9
Average weekly champagne plus white wine intake 0.9 1.2 3.7 -0.9 0.5 -1.6 -0.8 -1.9 0.4 -0.8 -0.9
Miserableness 0.5 0.9 2.2 1.4 -0.6 0.6 0.9 1.5 1.0 -0.2 -0.4
Guilty feelings 0.6 0.9 3.3 1.8 -1.0 0.2 0.8 1.4 0.0 0.4 -0.6
Wears glasses or contact lenses 0.8 0.9 3.7 -0.9 0.2 -0.2 -1.9 -0.1 -0.5 -1.3 -0.5
Ever taken oral contraceptive pill 0.7 0.8 2.4 -0.2 0.2 1.0 -0.4 0.7 -0.6 -1.5 -1.3
Hearing aid user 0.6 0.7 1.6 1.3 -0.1 0.7 -0.2 1.3 -1.1 0.3 0.7
Mother’s age at death 0.7 0.8 2.4 -0.4 -1.3 0.3 0.1 1.5 0.7 -0.3 -1.3
Financial situation satisfaction 0.5 0.6 1.7 1.3 -0.0 1.2 0.2 -0.6 0.5 -0.9 -0.4
Tinnitus: Yes, now most or all of the time 0.3 0.4 2.1 1.4 0.1 0.1 0.0 0.8 0.5 -0.2 0.4
Commuting to job workplace: Public transport 0.1 0.1 0.4 -0.5 0.1 -0.6 0.3 -0.1 0.6 0.0 -0.3
Eye problems/disorders: Glaucoma 1.7 2.1 5.2 -2.2 -0.4 0.6 -1.9 -1.4 0.5 -2.3 0.1
Medication: Blood pressure 0.8 1.5 3.2 0.8 0.6 -1.1 1.8 -1.8 1.5 0.3 1.2
Pain type(s) experienced in last month: Hip pain 0.1 0.1 0.3 -0.4 -0.0 0.6 0.1 -0.4 0.1 -0.1 -0.2
Supplements: Fish oil (including cod liver oil) 0.9 1.1 3.4 -1.5 1.8 -0.2 -1.2 -0.7 0.0 -0.8 -0.9
High cholesterol (Self-reported) 1.0 1.7 7.3 0.6 1.0 -0.2 -0.3 -2.7 0.3 -0.0 2.2
Medication: Bendroflumethiazide 0.4 0.7 2.4 0.2 -1.5 -0.0 -0.2 -1.4 0.8 -0.1 0.6
Medication: Paracetamol 0.5 0.8 1.7 -0.4 -1.3 1.0 -0.7 -1.1 0.9 -0.9 0.3
Medication: Lisinopril 0.5 0.7 1.9 1.3 0.1 0.7 0.8 0.1 -1.4 -0.3 0.6
Medication: Atorvastatin 0.3 0.4 1.0 -0.5 -0.6 0.9 -1.0 0.2 -0.8 -0.4 -0.2
Illnesses of father: High blood pressure 0.4 0.5 1.5 1.2 0.7 0.5 0.4 0.7 0.5 0.3 -0.6
Alcohol drinker status: Never 1.1 1.3 2.7 -0.8 1.6 0.5 -1.4 0.4 -0.6 -1.7 -1.4
Ever smoked 0.5 0.9 2.0 1.4 1.3 0.0 1.2 1.0 -0.4 0.6 1.1
Basal metabolic rate 0.2 1.2 3.8 1.5 0.6 0.8 1.2 1.9 0.6 0.8 -0.3
Leg fat percentage (left) 0.2 0.8 2.8 0.2 -1.2 0.3 -0.6 -1.7 1.2 -0.5 -0.2
Arm fat-free mass (left) 0.2 0.8 2.4 1.3 0.4 1.0 0.9 1.5 0.3 0.7 -0.2
Number of operations (self-reported) 0.5 0.7 2.2 1.1 0.7 -0.4 1.5 0.4 0.4 0.9 0.8
Average weekly beer plus cider intake 1.1 1.7 3.2 1.0 -0.4 0.5 1.3 1.5 -1.4 1.8 1.7
Irritability 1.2 2.0 4.6 1.1 -1.2 -0.3 1.7 -0.0 2.0 1.1 2.1
Risk taking 0.5 0.8 1.5 -0.9 0.1 1.0 -1.2 0.8 -0.4 -1.1 -1.0
Ever had prostate specific antigen (PSA) test 1.3 1.4 2.9 1.1 1.3 0.1 1.4 1.7 1.2 0.6 1.3
Fractured/broken bones in last 5 years 0.4 0.6 1.3 0.7 0.4 0.9 0.2 -0.3 1.0 -1.1 0.9
Age started oral contraceptive pill 0.5 0.6 1.5 -1.1 -0.5 -0.2 -1.1 -1.2 -0.7 -0.3 -0.2
Diastolic blood pressure, automated reading 0.3 0.8 2.1 -1.0 1.0 -0.1 0.4 -1.3 0.5 0.4 1.4
Ever depressed for a whole week 0.5 0.6 2.3 -0.2 -0.8 0.6 -0.3 0.5 0.4 -1.0 -1.5
Unable to work because of sickness or disability 0.2 0.3 1.0 0.4 0.8 0.2 -0.3 -0.2 -0.1 -1.0 -0.5
Commuting to job workplace: Cycle 1.2 1.5 3.0 0.3 1.7 -1.5 1.1 0.9 0.6 1.0 -1.7
Myopia 0.5 0.7 2.5 -0.9 -0.9 0.7 -0.4 1.6 -0.2 -0.9 0.1
Vascular/heart problems diagnosed by doctor 0.6 1.5 7.0 -1.3 -1.2 -1.0 -0.9 0.1 -0.1 -0.2 -2.6
Cholesterol lowering medication 1.3 1.9 11.1 0.7 -0.6 -0.3 0.8 -3.3 0.9 0.3 1.4
Medication: Omeprazole (e.g. Zanprol) 0.3 0.4 1.4 0.3 -0.1 -0.4 0.9 -0.1 1.2 0.9 0.2
Pain experienced in last month 0.9 1.5 3.7 1.4 -0.4 -1.7 1.3 0.4 -0.2 1.9 1.3
Supplements: Calcium 0.5 0.5 1.1 -1.0 0.8 -0.9 -0.6 -0.3 0.5 -0.6 -0.6
Basal cell carcinoma (self-reported) 0.8 0.9 3.8 -1.0 -0.1 -0.5 -0.7 -1.9 -1.1 -0.3 0.9
Heart attack/myocardial infarction (self-reported) 1.0 1.3 4.2 -0.4 -0.5 0.9 -2.1 -0.4 -1.4 -1.4 -0.8
Deep venous thrombosis (DVT) (self-reported) 1.2 1.5 6.5 -0.1 -1.4 0.9 0.4 0.6 -2.5 1.1 1.1
Heart disease (siblings) 0.5 0.6 2.7 0.6 -0.9 -0.1 0.4 -0.1 1.6 0.3 0.6
Alcohol drinker status: Previous 0.7 0.7 2.8 1.7 -0.3 0.2 1.2 0.8 0.1 0.2 1.0
Pack years of smoking 1.0 1.5 4.4 0.3 1.8 -1.5 0.3 -2.1 0.4 0.6 -1.1
Impedance of whole body 0.1 0.7 2.8 -1.2 0.6 0.2 -0.8 0.3 -0.5 -1.7 -0.3
Leg fat mass (left) 0.1 0.5 1.7 1.0 -0.5 0.5 0.0 -0.6 1.3 -0.0 -0.1
Arm predicted mass (left) 0.2 1.1 3.6 1.5 0.4 1.6 0.7 1.9 -0.0 0.4 0.1