TWAS hub - FAM198A

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1460	0.0410	2.1e-07	0.099	0.080	0.081	0.106	0.095	4.8e-12	5.6e-10	3.8e-10	7.2e-13	1.2e-11
2	ROSMAP	Brain Pre-frontal Cortex	0.0948	0.0304	2.7e-06	0.090	0.063	0.073	0.084	0.086	1.1e-11	1.6e-08	1.2e-09	6.6e-11	3.7e-11
3	TCGA	Colon Adenocarcinoma	0.1050	0.0470	3.9e-05	0.126	0.099	0.082	NA	0.110	1.0e-07	2.6e-06	1.7e-05	NA	7.0e-07

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Financial difficulties in last 2 years	7.1	9.6	14.5	0.5	3.8	3.7
Illness, injury, bereavement, stress in last 2 years	5.8	7.1	11.1	-1.2	-3.3	-3.0
Medication: Gliclazide	4.4	5.0	5.7	2.1	2.4	2.2
Hearing aid user	4.3	4.9	6.5	-1.4	-2.5	-2.5
Serious illness, injury or assault of a close relative in last 2 years	3.7	4.2	5.8	2.4	2.0	1.7
Basal cell carcinoma (self-reported)	3.6	4.3	5.6	-1.7	-2.4	-2.1
Frequency of tenseness / restlessness in last 2 weeks	3.2	4.9	7.4	0.9	2.7	2.6
Alcohol usually taken with meals	2.9	4.7	7.4	0.1	-2.7	-2.6
Fed-up feelings	2.5	4.6	5.9	1.5	2.4	2.3
Depression (self-reported)	2.4	2.9	4.2	-0.7	2.0	2.1
Maternal smoking around birth	2.3	3.3	7.2	-2.7	-1.2	-1.1
Frequency of unenthusiasm / disinterest in last 2 weeks	2.3	3.0	4.0	-1.1	1.9	2.0
Qualifications: nursing, teaching	2.3	3.6	5.3	-1.2	-2.3	-2.0
Schizophrenia vs Biploar Disorder	2.2	2.9	3.2	-1.6	-1.6	-1.8
Knee pain experienced in last month	2.2	3.4	5.7	0.6	2.4	2.0
Miserableness	2.2	3.8	5.6	1.2	2.4	2.1
Heart disease (siblings)	2.2	2.7	4.9	2.2	1.5	1.0
Sitting height	2.1	14.8	37.8	6.2	2.2	1.3
Mouth/teeth dental problems: Bleeding gums	2.1	2.7	3.9	0.8	1.9	2.0
Depressed Affect (Nagel 2018)	2.0	4.2	6.8	0.3	2.6	2.4
Frequency of depressed mood in last 2 weeks	2.0	2.8	4.1	0.7	2.0	2.0
Medication: Simvastatin	2.0	3.0	3.3	1.8	1.8	1.5
Gout (self-reported)	2.0	2.8	4.2	-0.7	-1.9	-2.0
Number of full sisters	1.9	2.3	3.5	0.2	1.9	1.8
Financial situation satisfaction	1.9	2.3	3.5	0.2	1.8	1.9
Schizophrenia (2018)	1.8	3.8	4.1	-2.0	-1.9	-2.0
Fasting Glucose	1.8	2.2	3.1	1.3	1.8	1.3
Medication: Seretide 50 evohaler	1.8	2.1	2.5	-1.2	-1.6	-1.6
Had major operations	1.8	2.1	2.5	-1.5	-1.3	-1.6
Depression (Nagel 2018)	1.7	2.6	3.9	-0.4	2.0	1.9
Major Depression (MDD)	1.7	2.1	2.7	-1.6	-1.2	-1.4
Hair/balding pattern: Pattern 2	1.7	2.1	2.6	1.4	-1.4	-1.6
Ovarian Cancer	1.6	2.2	3.2	-1.2	-1.8	-1.4
Hand grip strength (right)	1.6	4.4	7.4	0.9	2.3	2.7
Pain all over the body in last month	1.6	1.7	2.6	-1.6	-1.1	-1.1
Falls in the last year	1.6	2.1	5.6	-2.4	-0.7	-0.5
Commuting to job workplace: Public transport	1.6	1.9	2.5	-0.8	-1.6	-1.6
Medication: Omeprazole (e.g. Zanprol)	1.6	2.0	3.8	-1.9	0.8	1.2
Taking other prescription medications	1.5	2.3	6.5	-2.6	-0.4	-0.5
Standing height	1.5	14.9	37.1	6.1	2.3	1.5
Loud music exposure frequency	1.5	1.6	4.8	-2.2	-0.2	-0.1
Risk taking	1.5	2.2	6.4	-2.5	-0.4	-0.2
Crohns Disease (2012)	1.4	2.3	4.8	-2.2	-1.0	-1.1
Pulse rate	1.4	2.4	3.4	1.2	1.8	1.6
Birth weight of first child	1.4	2.5	5.0	2.2	-0.9	-1.2
Medication: Omeprazole	1.4	1.7	4.8	-2.2	-0.1	0.5
Handedness (chirality/laterality): Left-handed	1.4	1.7	2.0	-1.4	-1.2	-1.3
Hand grip strength (left)	1.3	3.4	3.9	1.6	1.9	2.0
Number of treatments/medications taken	1.3	2.4	4.1	-2.0	-1.2	-1.3
Ever had hysterectomy (womb removed)	1.3	1.4	1.8	-1.1	1.1	1.3
Townsend deprivation index at recruitment	1.3	1.8	2.9	1.3	1.7	0.9
Chronic bronchitis/emphysema (mother)	1.3	1.5	2.4	-1.5	-1.3	-0.6
Pulse wave peak to peak time	1.3	1.6	1.8	1.1	1.3	1.3
Illnesses of father: Heart disease	1.3	1.8	2.7	-0.4	1.6	1.6
Medication: Lisinopril	1.3	1.7	2.3	-1.5	-1.4	-1.0
Ever had prostate specific antigen (PSA) test	1.3	1.5	1.7	-1.3	-1.3	-1.1
Blood White Count	1.2	8.5	13.2	-1.3	3.3	3.6
Height	1.2	23.6	64.0	8.0	2.4	0.9
Time employed in main current job	1.2	1.4	3.1	1.8	-0.7	-0.8
Emphysema/chronic bronchitis	1.2	1.3	2.7	-1.6	-0.8	-0.8
Myopia	1.2	1.7	3.3	-1.8	-1.0	-0.9
Bipolar Disorder or Schizophrenia	1.1	2.8	4.7	-2.2	-1.3	-1.4
Qualifications: None of the above	1.1	2.4	4.2	0.3	2.0	1.7
Mouth/teeth dental problems	1.1	1.6	2.6	-0.1	-1.6	-1.5
Length of working week for main job	1.1	1.2	2.0	1.4	1.0	0.7
Pulse wave reflection index	1.1	1.4	1.6	-1.2	-1.2	-1.1
Illnesses of siblings: Diabetes	1.1	1.4	3.1	1.8	0.9	0.5
Unable to work because of sickness or disability	1.1	1.4	4.3	-2.1	0.2	0.0
Heart attack/myocardial infarction (self-reported)	1.1	1.4	3.3	-1.8	-0.7	-0.6
Neuroticism (Nagel 2018)	1.0	2.2	3.6	0.9	1.9	1.5
Neuroticism	1.0	2.4	3.3	1.5	1.8	1.3
Medication: Metformin	1.0	1.4	2.1	0.2	-1.4	-1.4
Neuroticism score	1.0	2.1	3.1	0.9	1.7	1.5
Impedance of arm (right)	1.0	4.6	11.6	3.4	1.4	0.7
Frequency of tiredness / lethargy in last 2 weeks	1.0	1.6	2.6	-0.6	1.3	1.6
Tense / ‘highly strung’	1.0	1.7	2.8	0.6	1.7	1.4
Eye problems/disorders: None of the above	1.0	1.1	1.6	-1.2	-1.2	-0.4
Comparative height size at age 10	1.0	5.2	15.4	3.9	0.6	-0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.0	1.1	2.7	-1.6	0.3	0.8
Mineral and other dietary supplements	1.0	1.3	2.0	0.2	-1.4	-1.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.0	2.1	3.5	-0.3	-1.9	-1.7
Medication: Bendroflumethiazide	1.0	1.5	2.2	-0.7	-1.4	-1.5
Triglycerides	0.9	1.4	2.2	-0.5	1.5	1.4
Eye problems/disorders: Diabetes related eye disease	0.9	1.0	2.7	1.6	0.5	0.0
Medication: Levothyroxine sodium	0.9	1.5	2.0	-0.7	-1.4	-1.4
Diabetes (self-reported)	0.9	1.4	2.4	0.1	-1.3	-1.5
Medication: Lansoprazole	0.9	1.0	1.5	-0.8	1.2	0.9
Pulse wave Arterial Stiffness index	0.9	1.1	1.4	-0.6	-1.2	-1.2
Worry too long after embarrassment	0.9	1.6	4.4	2.1	0.3	0.5
Migraine (self-reported)	0.9	1.1	1.9	-1.4	0.7	0.9
Pulse rate, automated reading	0.9	3.1	4.6	1.3	2.1	1.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.9	1.0	1.9	-0.6	0.9	1.4
Average weekly beer plus cider intake	0.9	1.2	2.1	0.2	1.4	1.3
Alzheimer’s Disease (in father)	0.8	0.9	1.7	-1.3	0.5	0.8
Age at First Birth	0.8	1.1	2.7	1.6	-0.4	-0.7
HbA1C	0.8	0.9	1.5	1.2	1.0	0.4
Type 2 Diabetes (T2D) (2012)	0.8	1.0	1.4	0.4	1.2	1.2
Diabetes (mother)	0.8	1.0	2.8	1.7	0.1	-0.6
Worrier / anxious feelings	0.8	1.5	2.1	1.5	1.2	1.0
Illnesses of mother	0.8	1.0	1.6	-0.0	1.3	1.2
Impedance of arm (left)	0.8	3.5	9.4	3.1	1.0	0.3
Ever highly irritable/argumentative for 2 days	0.8	1.0	1.5	-0.0	1.2	1.2
Commuting to job workplace: Walk	0.8	0.9	2.3	1.5	0.5	0.3
Osteoporosis (self-reported)	0.8	1.0	1.4	-0.7	-1.1	-1.2
Relative age of first facial hair	0.7	1.4	3.0	-1.7	-1.0	-0.4
Severe depression (siblings)	0.7	0.8	1.2	-0.8	-0.8	-1.1
Chronic bronchitis/emphysema (father)	0.7	0.9	1.5	0.2	1.2	1.0
Number of live births	0.7	1.0	1.3	-0.7	1.1	1.1
Family relationship satisfaction	0.7	0.8	1.5	0.8	1.2	0.6
Loneliness, isolation	0.7	0.9	1.5	-0.6	0.9	1.2
Ever had stillbirth, spontaneous miscarriage or termination	0.7	0.7	1.7	-1.3	0.5	0.4
Ulcerative Colitis (UC)	0.6	1.1	3.0	1.7	-0.4	-0.5
Mean Putamen Volume	0.6	0.7	1.3	-0.3	0.8	1.2
LDL Cholesterol	0.6	1.0	1.4	-0.4	1.2	1.2
Rheumatoid Arthritis	0.6	0.8	1.5	-0.1	-1.2	-1.0
Blood Eosinophil Count	0.6	4.6	5.1	-2.1	2.3	2.1
BMI	0.6	3.5	3.8	-1.7	-1.9	-1.9
Waist Hip Ratio (WHR)	0.6	2.6	3.9	1.7	2.0	1.0
Pack years adult smoking proportion	0.6	0.8	1.2	-0.6	1.0	1.1
Average weekly fortified wine intake	0.6	0.7	2.0	-1.4	-0.3	-0.2
Prospective memory result	0.6	0.8	1.2	-0.7	-0.8	-1.1
Shortness of breath walking on level ground	0.6	0.7	1.4	0.2	1.2	0.8
Qualifications: College or University degree	0.6	1.8	1.9	1.3	-1.3	-1.4
Mean time to correctly identify matches	0.6	1.0	1.4	0.8	-1.2	-1.0
Heart disease (mother)	0.6	0.7	1.2	0.2	-1.0	-1.1
Commuting to job workplace: Car/motor vehicle	0.6	0.7	1.7	-1.3	-0.5	-0.3
Leg fat-free mass (right)	0.6	3.0	8.4	2.9	0.8	0.1
Average weekly red wine intake	0.6	0.9	1.2	-1.1	-1.1	-0.6
Leg predicted mass (right)	0.6	3.2	8.7	3.0	0.9	0.2
Number of self-reported non-cancer illnesses	0.6	1.1	1.9	0.3	1.4	1.1
Mother’s age at death	0.6	0.8	1.2	0.4	-1.1	-1.0
Supplements: Fish oil (including cod liver oil)	0.6	0.8	1.1	0.5	1.1	1.0
Irritability	0.6	1.0	1.4	-0.5	1.2	1.2
Worry (Nagel 2018)	0.5	1.0	1.2	1.0	1.1	0.8
Alzheimer’s Disease (in mother)	0.5	0.6	1.0	0.2	0.8	1.0
Average weekly spirits intake	0.5	0.6	1.0	-0.4	0.9	1.0
Systolic blood pressure, automated reading	0.5	1.4	2.8	1.7	-0.7	-1.0
Vitamin and mineral supplements	0.5	0.6	0.9	0.9	0.6	0.7
Diabetes (father)	0.5	0.6	1.3	1.1	-0.5	-0.6
Leg fat-free mass (left)	0.5	2.5	7.1	2.7	0.6	-0.1
Age when periods started (menarche)	0.5	1.2	2.8	-1.7	-0.8	-0.3
Serious illness, injury or assault to yourself	0.5	0.6	1.9	-1.4	0.0	0.0
Stomach or abdominal pain in last month	0.5	0.7	1.7	-1.3	0.3	0.4
High blood pressure (mother)	0.5	0.8	1.2	-0.6	-1.1	-0.9
Leg predicted mass (left)	0.5	2.5	7.1	2.7	0.5	-0.1
Nervous feelings	0.5	0.9	1.0	0.9	1.0	1.0
Heart attack	0.5	0.6	1.6	-1.3	-0.3	-0.2
Blood clot in the leg (DVT)	0.5	0.6	1.0	0.2	1.0	0.9
Medication: Ventolin 100micrograms inhaler	0.5	0.6	1.1	-0.3	1.1	0.8
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.6	1.4	-1.2	-0.3	-0.5
Neck or shoulder pain in last month	0.5	0.7	2.1	-1.4	-0.0	-0.1
Medication: Allopurinol	0.5	0.6	1.0	-0.4	-0.9	-1.0
Chest pain or discomfort	0.5	0.7	0.9	-0.8	1.0	0.7
Eye problems/disorders: Cataract	0.5	0.6	1.0	0.7	1.0	0.5
Mouth/teeth dental problems: Mouth ulcers	0.5	0.7	0.9	-0.9	-0.8	-0.8
Smoking status: Current	0.5	0.8	2.2	-1.5	0.2	0.3
Age started oral contraceptive pill	0.5	0.6	0.9	0.5	-1.0	-0.8
Alcohol drinker status: Previous	0.5	0.6	1.1	-0.4	-0.7	-1.0
Impedance of whole body	0.5	2.3	4.8	2.2	1.2	0.9
Alzheimer’s Disease (including proxy)	0.4	0.5	0.8	-0.7	0.6	0.9
Irritable Bowel Disease (IBD)	0.4	1.0	1.5	1.2	-0.7	-1.0
Reaction Time	0.4	0.8	0.9	0.7	-0.9	-1.0
Coronary Artery Disease (CAD)	0.4	0.5	1.3	-1.1	0.2	0.2
Schizophrenia (2014)	0.4	0.8	1.3	-1.1	-0.6	-0.9
Systolic Blood Pressure	0.4	1.8	5.3	2.3	0.2	0.0
Chronotype (morning person)	0.4	0.8	1.4	0.4	1.2	1.0
Sensitivity / hurt feelings	0.4	0.6	0.7	-0.7	0.8	0.9
Supplements: Zinc	0.4	0.5	0.7	0.5	0.7	0.8
Multivitamins +/- minerals	0.4	0.6	1.1	-1.0	-0.5	-0.6
Had other major operations	0.4	0.5	0.8	-0.6	0.6	0.9
Mouth/teeth dental problems: Loose teeth	0.4	0.4	1.2	-1.1	0.2	0.3
Diabetes diagnosed by doctor	0.4	0.7	1.1	0.2	-0.9	-1.1
Breast cancer (self-reported)	0.4	0.5	0.7	0.7	0.6	0.8
Asthma (self-reported)	0.4	0.8	1.4	0.3	1.2	0.9
Average weekly champagne plus white wine intake	0.4	0.5	0.6	-0.8	-0.8	-0.5
Ever taken oral contraceptive pill	0.4	0.4	1.2	-1.1	-0.4	0.1
Cholesterol lowering medication	0.4	0.6	1.3	-1.1	0.4	0.5
Deep venous thrombosis (DVT) (self-reported)	0.4	0.6	0.8	0.5	0.9	0.8
Pack years of smoking	0.4	0.6	0.9	-0.4	0.9	1.0
Bipolar Disorder (2018)	0.3	0.4	1.1	-1.1	0.3	0.3
Body Mass Index (BMI) (2010)	0.3	0.4	0.9	-0.9	-0.5	-0.2
Ulcerative Colitis	0.3	0.4	0.6	0.5	0.7	0.7
Blood Red Count	0.3	3.3	5.1	2.3	1.6	1.6
Smoking Status	0.3	0.7	1.6	-0.2	1.2	0.7
Other serious medical condition/disability diagnosed by doctor	0.3	0.3	0.5	0.7	0.6	0.4
Ever used hormone-replacement therapy (HRT)	0.3	0.4	1.0	-1.0	-0.3	-0.1
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	0.7	-0.8	0.5	0.2
Diverticular disease/diverticulitis (self-reported)	0.3	0.4	0.9	1.0	0.3	0.1
Past tobacco smoking	0.3	0.6	1.0	1.0	-0.9	-0.4
Forced vital capacity (FVC)	0.3	1.1	2.9	1.7	-0.4	-0.5
Hair/balding pattern: Pattern 3	0.3	0.4	1.3	-1.1	0.1	0.2
Forced expiratory volume in 1-second (FEV1)	0.3	1.1	2.0	1.4	-0.8	-0.7
Noisy workplace	0.3	0.4	0.7	0.1	0.8	0.6
Qualifications: A levels/AS levels or equivalent	0.3	0.7	1.0	1.0	0.7	0.8
Asthma	0.3	0.6	1.1	0.4	1.0	0.7
Medication: Cholesterol lowering	0.3	0.4	1.2	1.1	0.2	0.0
Lung cancer (father)	0.3	0.3	0.6	-0.0	0.6	0.8
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	0.9	1.3	0.3	-1.2	-1.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.4	1.0	-1.0	0.3	0.4
Forced vital capacity (FVC), Best measure	0.3	1.1	1.4	0.7	-1.2	-1.2
Leg fat percentage (right)	0.3	1.2	2.3	-1.5	-0.9	-0.7
Comparative body size at age 10	0.3	0.8	1.8	-1.4	-0.6	-0.2
Suffer from ‘nerves’	0.3	0.4	0.7	-0.5	0.6	0.8
Overall health rating	0.3	0.6	1.7	-1.3	0.3	-0.2
Smoking status: Previous	0.3	0.4	1.0	0.1	1.0	0.4
Whole body fat-free mass	0.3	1.5	4.3	2.1	0.4	0.0
Mood swings	0.3	0.6	1.8	-1.3	0.2	0.1
Ever had bowel cancer screening	0.3	0.4	0.7	0.8	0.4	0.6
Whole body water mass	0.3	1.5	4.2	2.1	0.4	0.0
Tinnitus: Yes, now most or all of the time	0.3	0.3	0.5	-0.4	0.6	0.7
Medication: Paracetamol	0.3	0.5	0.9	-0.1	0.9	0.8
Ever smoked	0.3	0.6	1.2	-1.1	-0.4	-0.7
Ever depressed for a whole week	0.3	0.4	1.2	1.1	0.2	-0.2
Vascular/heart problems diagnosed by doctor	0.3	0.8	2.2	1.5	0.2	-0.0
HDL Cholesterol	0.2	0.4	1.1	1.0	-0.3	-0.3
Primary Biliary Cirrhosis	0.2	0.3	0.4	-0.4	-0.7	-0.7
Cardiovascular Disease	0.2	0.6	0.7	-0.7	0.8	0.8
Lung FVC	0.2	0.8	1.6	-0.2	-1.2	-0.9
Hair Pigment	0.2	6.7	12.2	-3.5	-2.3	-1.6
Hearing difficulty/problems: Yes	0.2	0.3	0.6	0.4	-0.5	-0.8
Angina	0.2	0.2	0.6	-0.8	-0.1	0.1
Current tobacco smoking	0.2	0.4	1.0	-1.0	0.2	0.3
Relative age voice broke	0.2	0.3	1.0	-1.0	-0.1	0.1
Bilateral oophorectomy (both ovaries removed)	0.2	0.2	0.6	-0.3	0.2	0.8
Supplements: Glucosamine	0.2	0.3	0.6	-0.8	-0.5	-0.2
Trunk fat mass	0.2	0.9	2.7	1.6	0.1	-0.3
Hearing difficulty/problems with background noise	0.2	0.4	1.0	-1.0	0.1	0.1
Allergy	0.2	0.6	0.7	0.6	-0.8	-0.8
Medication: Ramipril	0.2	0.3	0.5	-0.7	-0.4	-0.4
Fluid intelligence score	0.2	0.4	1.1	1.1	-0.3	0.1
Weight	0.2	0.9	2.5	1.6	0.3	-0.1
Arm fat percentage (right)	0.2	0.6	1.2	0.2	-0.8	-1.1
Trunk fat-free mass	0.2	1.2	3.4	1.9	0.4	0.2
Hip circumference	0.2	0.8	1.1	0.4	-1.1	-1.0
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.3	0.9	-0.9	0.1	-0.2
Trunk predicted mass	0.2	1.1	3.2	1.8	0.4	0.2
Hair/balding pattern: Pattern 4	0.2	0.5	1.2	1.1	0.5	0.3
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	0.6	0.8	-0.3	0.3
Medication: Paracetamol	0.2	0.4	1.1	-1.1	0.0	0.1
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	0.9	1.0	0.4	0.2
Exposure to tobacco smoke outside home	0.2	0.3	0.4	-0.6	0.4	0.6
Wheeze or whistling in the chest in last year	0.2	0.4	0.7	-0.3	0.9	0.7
Medication for pain relief, constipation, heartburn	0.2	0.4	0.6	0.8	-0.5	-0.4
Medication: Ibuprofen	0.2	0.3	0.4	-0.6	0.6	0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.2	0.6	-0.8	-0.0	0.1
Alcohol intake frequency.	0.2	0.5	1.1	1.1	0.5	-0.2
Age at last live birth	0.2	0.3	0.4	0.6	0.3	0.5
Medication: Aspirin	0.2	0.2	0.2	0.5	0.5	0.5
Hypertension (Self-reported)	0.2	0.6	1.6	-1.3	-0.3	-0.2
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.3	0.8	0.9	0.4	0.1
Friendships satisfaction	0.2	0.3	0.4	-0.1	-0.7	-0.6
Medication for cholesterol	0.2	0.4	1.1	1.0	-0.1	-0.1
Back pain experienced in last month	0.2	0.3	0.7	-0.8	0.2	0.4
Guilty feelings	0.2	0.4	0.6	0.8	0.6	0.5
High cholesterol (Self-reported)	0.2	0.3	0.5	0.1	0.7	0.6
Medication: Atorvastatin	0.2	0.2	0.4	-0.6	-0.4	-0.2
Basal metabolic rate	0.2	1.4	4.0	2.0	0.4	-0.1
Leg fat percentage (left)	0.2	0.9	1.8	-1.4	-0.7	-0.5
Number of operations (self-reported)	0.2	0.3	1.0	-1.0	0.1	0.1
Commuting to job workplace: Cycle	0.2	0.3	0.6	0.8	0.4	0.1
Intelligence (Savage-Jansen 2018)	0.1	0.2	0.4	0.4	-0.6	-0.1
Crohns Disease (2017)	0.1	0.3	0.7	0.0	-0.5	-0.8
Verbal and Numeric Reasoning (VNR)	0.1	0.2	0.4	-0.4	-0.1	0.6
Bipolar Disorder (2011)	0.1	0.1	0.2	0.4	0.2	-0.1
Blood Platelet Count	0.1	1.7	3.6	1.9	1.0	0.8
Allergy or Eczema	0.1	0.1	0.4	-0.7	-0.1	-0.0
Hypothyroidism (self reported)	0.1	0.3	0.6	0.8	0.4	0.5
Respiratory disease	0.1	0.2	0.4	0.1	0.7	0.5
Type 2 Diabetes (T2D) (2018)	0.1	0.3	0.4	0.5	-0.4	-0.7
Lung FEV1/FVC ratio	0.1	0.3	0.4	-0.6	-0.6	-0.1
Tanning	0.1	0.9	1.2	1.0	1.1	0.7
Medication for hormone replacement therapy	0.1	0.1	0.3	-0.5	0.0	0.1
Medication: Co-codamol	0.1	0.1	0.4	-0.6	-0.1	0.2
Impedance of leg (right)	0.1	0.2	0.5	-0.3	0.3	0.7
Trunk fat percentage	0.1	0.5	1.5	1.2	0.1	-0.3
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.2	0.4	-0.2	-0.6	-0.4
Qualifications: CSEs or equivalent	0.1	0.1	0.2	0.3	0.4	0.3
High blood pressure	0.1	0.4	1.2	-1.1	-0.1	0.0
Medication: Atenolol	0.1	0.1	0.2	0.1	0.4	0.4
Body mass index (BMI)	0.1	0.6	0.9	-1.0	-0.6	-0.7
Impedance of leg (left)	0.1	0.7	1.4	-0.1	0.8	1.2
Number of incorrect matches in round	0.1	0.2	0.3	-0.3	-0.4	-0.5
Had menopause	0.1	0.2	0.3	-0.1	-0.4	-0.6
Ever unenthusiastic/disinterested for a whole week	0.1	0.1	0.3	0.0	-0.1	-0.5
Hayfever/allergic rhinitis (self-reported)	0.1	0.2	0.4	-0.7	-0.1	-0.1
Illnesses of siblings	0.1	0.1	0.2	-0.5	-0.1	0.3
Alcohol intake versus 10 years previously	0.1	0.2	0.2	-0.4	0.5	0.2
Happiness	0.1	0.1	0.1	-0.2	0.4	0.2
Arm fat mass (right)	0.1	0.3	0.6	0.5	-0.4	-0.8
Breastfed as a baby	0.1	0.2	0.3	0.2	0.4	0.5
Peak expiratory flow (PEF)	0.1	0.2	0.7	0.8	-0.0	0.1
Medication: Amlodipine	0.1	0.1	0.1	0.4	0.2	0.3
Birth weight	0.1	0.2	0.3	0.5	0.5	0.1
High blood pressure (siblings)	0.1	0.1	0.2	-0.4	0.3	0.2
Body fat percentage	0.1	0.2	0.4	0.3	-0.4	-0.6
Arm fat-free mass (right)	0.1	0.5	1.4	1.2	0.3	0.1
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.2	0.4	0.6	0.2	0.2
Age at first live birth	0.1	0.2	0.3	0.3	-0.5	-0.4
Health satisfaction	0.1	0.2	0.3	-0.5	0.5	0.3
Medication: Blood pressure	0.1	0.2	0.5	-0.7	-0.0	0.2
Angina (self-reported)	0.1	0.1	0.2	-0.5	0.1	0.2
Whole body fat mass	0.1	0.4	0.6	0.8	-0.3	-0.6
Arm predicted mass (right)	0.1	0.4	1.1	1.0	0.1	-0.1
Leg pain on walking	0.1	0.2	0.3	-0.6	0.4	0.2
Arm fat percentage (left)	0.1	0.6	1.2	0.0	-0.8	-1.1
Long-standing illness, disability or infirmity	0.1	0.1	0.3	-0.3	0.5	0.3
Arm fat mass (left)	0.1	0.4	0.8	0.2	-0.6	-0.9
Eye problems/disorders: Glaucoma	0.1	0.1	0.2	0.4	0.3	-0.2
Medication: Blood pressure	0.1	0.2	0.5	-0.7	0.3	0.3
Alcohol drinker status: Never	0.1	0.1	0.2	-0.2	0.5	0.1
Arm fat-free mass (left)	0.1	0.6	1.3	1.2	0.5	0.3
Fractured/broken bones in last 5 years	0.1	0.1	0.2	-0.4	0.5	0.3
Supplements: Calcium	0.1	0.1	0.3	-0.5	-0.0	-0.3
Arm predicted mass (left)	0.1	0.5	1.4	1.2	0.3	0.2
Breast Cancer	0.0	0.1	0.2	-0.5	0.2	0.1
Prostate Cancer	0.0	0.0	0.1	0.3	0.1	0.1
Lupus	0.0	0.1	0.1	0.2	0.2	0.2
Neuroticism (2016)	0.0	0.0	0.1	0.0	0.2	-0.1
Heel T-Score	0.0	0.1	0.2	-0.2	-0.4	-0.3
Hayfever, allergic rhinitis or eczema	0.0	0.1	0.2	-0.5	-0.2	-0.2
Waist circumference	0.0	0.0	0.1	0.2	0.1	-0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.0	0.1	0.2	-0.2	-0.4	-0.3
Father’s age at death	0.0	0.0	0.1	0.3	0.1	-0.0
Mouth/teeth dental problems: Dentures	0.0	0.1	0.2	0.1	0.4	0.2
Exposure to tobacco smoke at home	0.0	0.0	0.1	0.3	-0.1	-0.1
Headache pain in last month	0.0	0.1	0.1	0.2	0.0	-0.3
Medication for cholesterol, blood pressure or diabetes	0.0	0.1	0.1	0.0	0.3	0.2
Glaucoma (self-reported)	0.0	0.0	0.0	-0.1	0.1	-0.2
Number of full brothers	0.0	0.0	0.0	-0.1	0.1	-0.2
Number of children fathered	0.0	0.0	0.1	-0.3	-0.1	-0.2
Leg fat mass (right)	0.0	0.2	0.3	-0.3	-0.5	-0.5
Qualifications: NVQ or HND or HNC or equivalent	0.0	0.0	0.0	0.1	0.2	-0.0
Supplements: Vitamin C	0.0	0.0	0.0	-0.2	-0.0	-0.1
Osteoarthritis (self-reported)	0.0	0.1	0.1	-0.1	0.2	0.4
Medication: Aspirin	0.0	0.1	0.1	-0.3	0.2	0.3
Illnesses of father: None of the above (group 1)	0.0	0.0	0.0	0.1	-0.1	-0.1
Wears glasses or contact lenses	0.0	0.0	0.0	-0.2	-0.2	-0.2
Pain type(s) experienced in last month: Hip pain	0.0	0.0	0.0	0.1	0.1	0.0
Illnesses of father: High blood pressure	0.0	0.0	0.0	0.2	-0.0	-0.2
Diastolic blood pressure, automated reading	0.0	0.1	0.2	-0.1	-0.4	-0.5
Pain experienced in last month	0.0	0.1	0.1	0.2	-0.4	0.1
Leg fat mass (left)	0.0	0.1	0.2	-0.1	-0.3	-0.4

Hub : Genes

FAM198A

Models

Trait associations