TWAS hub - FAM21C

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.327	0.0810	3.1e-08	0.097	0.094	0.101	0.108	0.093	6.8e-12	1.8e-11	2.6e-12	4.8e-13	2.0e-11
2	GTEx	Adipose Subcutaneous	0.371	0.0670	1.6e-13	0.065	NA	0.173	NA	0.168	5.1e-06	NA	4.6e-14	NA	1.1e-13
3	GTEx	Adipose Visceral Omentum	0.359	0.1100	3.7e-03	0.025	NA	0.058	NA	0.055	1.7e-02	NA	5.7e-04	NA	7.7e-04
4	GTEx	Adrenal Gland	0.372	0.1080	4.0e-04	-0.008	NA	0.164	NA	0.071	1.0e+00	NA	1.7e-06	NA	1.6e-03
5	GTEx	Artery Aorta	0.230	0.1610	5.1e-03	-0.004	NA	0.011	NA	-0.001	7.2e-01	NA	7.6e-02	NA	3.9e-01
6	GTEx	Artery Tibial	0.387	0.0790	2.6e-09	0.150	NA	0.143	NA	0.148	7.8e-12	NA	2.7e-11	NA	1.1e-11
7	GTEx	Brain Cerebellar Hemisphere	0.200	0.0980	5.0e-03	0.086	NA	0.001	NA	0.037	3.2e-03	NA	3.1e-01	NA	4.0e-02
8	GTEx	Brain Cerebellum	0.246	0.0950	1.1e-03	0.158	NA	0.114	NA	0.138	2.1e-05	NA	3.0e-04	NA	7.0e-05
9	GTEx	Breast Mammary Tissue	0.251	0.0740	3.6e-08	0.180	NA	0.217	NA	0.201	1.5e-09	NA	2.1e-11	NA	1.3e-10
10	GTEx	Breast Mammary Tissue (Male)	0.183	0.0842	5.4e-03	0.055	NA	0.038	NA	0.086	2.1e-02	NA	4.7e-02	NA	5.0e-03
11	GTEx	Breast Mammary Tissue (Female)	0.156	0.1011	2.9e-02	0.093	NA	0.080	NA	0.113	1.0e-03	NA	2.3e-03	NA	3.0e-04
12	GTEx	Cells Transformed fibroblasts	0.420	0.0780	3.2e-07	0.040	NA	0.100	NA	0.095	5.2e-04	NA	5.9e-08	NA	1.3e-07
13	GTEx	Colon Transverse	0.253	0.1180	6.4e-03	0.023	NA	0.108	NA	0.091	2.9e-02	NA	8.2e-06	NA	4.3e-05
14	GTEx	Esophagus Gastroesophageal Junction	0.225	0.0920	3.3e-03	0.116	NA	0.033	NA	0.062	5.7e-05	NA	2.3e-02	NA	2.8e-03
15	GTEx	Esophagus Mucosa	0.212	0.0800	1.1e-04	0.078	NA	0.066	NA	0.067	6.4e-06	NA	3.2e-05	NA	2.8e-05
16	GTEx	Esophagus Muscularis	0.388	0.0900	6.8e-07	0.059	NA	0.118	NA	0.063	1.7e-04	NA	1.3e-07	NA	1.1e-04
17	GTEx	Muscle Skeletal	0.188	0.0632	3.3e-05	0.060	NA	0.031	NA	0.058	1.6e-06	NA	4.3e-04	NA	2.1e-06
18	GTEx	Nerve Tibial	0.280	0.0777	1.7e-07	0.051	NA	0.128	NA	0.086	1.6e-04	NA	2.5e-09	NA	1.1e-06
19	GTEx	Pituitary	0.275	0.0970	2.9e-03	0.237	NA	0.103	NA	0.199	1.2e-06	NA	1.5e-03	NA	9.9e-06
20	GTEx	Skin Not Sun Exposed Suprapubic	0.281	0.0980	5.3e-05	0.003	NA	0.066	NA	0.055	2.2e-01	NA	1.7e-04	NA	5.4e-04
21	GTEx	Skin Sun Exposed Lower leg	0.124	0.0420	6.4e-07	0.088	NA	0.104	NA	0.107	8.8e-08	NA	6.3e-09	NA	3.8e-09
22	GTEx	Spleen	0.581	0.1150	1.0e-03	0.009	NA	0.132	NA	0.059	1.8e-01	NA	3.0e-04	NA	1.3e-02
23	GTEx	Stomach	0.221	0.1050	1.5e-03	0.050	NA	0.104	NA	0.074	2.1e-03	NA	1.2e-05	NA	2.1e-04
24	GTEx	Testis	0.161	0.0630	7.1e-05	0.123	NA	0.137	NA	0.141	4.2e-06	NA	1.2e-06	NA	8.4e-07
25	GTEx	Thyroid	0.153	0.0650	5.0e-04	0.060	NA	0.032	NA	0.046	2.1e-05	NA	1.5e-03	NA	1.9e-04
26	GTEx	Whole Blood	0.178	0.0550	7.2e-07	0.046	NA	0.079	NA	0.093	4.6e-05	NA	9.1e-08	NA	6.7e-09

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26
Blood Red Count	8.6	83.4	151.3	0.2	10.2	4.5	8.4	6.1	10.8	11.9	11.8	9.6	10.9	8.9	4.1	5.8	11.2	10.6	7.0	10.7	7.3	2.4	10.2	12.2	5.0	11.1	12.3	10.3	8.7
Eye problems/disorders: Glaucoma	6.3	7.4	17.1	2.5	3.6	2.4	3.3	2.0	2.6	3.3	3.2	2.0	2.6	3.2	1.0	1.3	2.8	3.0	1.5	2.6	2.2	1.3	3.0	3.3	1.5	4.1	3.0	3.1	3.3
Illnesses of father: None of the above (group 1)	3.9	4.8	11.4	-0.5	-1.6	-1.2	-2.3	-1.4	-2.6	-2.3	-2.5	-2.3	-2.6	-2.6	-3.4	-1.7	-2.5	-2.7	-1.7	-2.5	-1.0	-0.7	-2.2	-2.2	-1.5	-2.5	-2.6	-2.7	-2.1
Rheumatoid Arthritis	3.2	4.4	9.0	-1.3	-2.7	-2.7	-3.0	-0.9	-1.7	-2.0	-2.0	-1.7	-1.7	-2.5	-3.0	-1.7	-1.8	-2.1	-2.4	-1.5	-2.3	-0.6	-2.2	-2.2	-1.1	-2.5	-2.0	-2.2	-2.6
Noisy workplace	2.9	3.6	9.4	-0.2	-3.1	-2.1	-1.1	0.3	-1.5	-1.9	-1.8	-1.7	-1.5	-2.2	-1.9	-1.2	-1.7	-1.8	-0.5	-1.3	-1.4	0.2	-2.7	-2.8	-2.5	-2.5	-2.4	-1.9	-2.9
Mouth/teeth dental problems: Mouth ulcers	2.9	4.7	8.4	1.5	2.4	2.0	1.1	1.4	2.4	2.1	2.3	2.9	2.4	2.9	2.0	0.5	2.1	2.8	0.7	2.5	1.7	-1.7	2.4	2.8	0.9	1.6	2.8	2.8	2.7
Ever had prostate specific antigen (PSA) test	2.8	3.2	5.8	-0.2	1.9	1.0	1.2	0.0	2.3	1.8	2.0	2.1	2.2	2.4	0.9	1.0	2.1	2.4	-0.2	2.0	1.6	-0.1	2.2	2.0	1.1	2.2	2.4	2.4	2.0
Depression (self-reported)	2.7	3.2	7.2	2.3	1.5	1.9	1.9	2.7	2.3	1.9	2.1	1.9	2.3	2.0	1.0	1.4	2.1	2.3	1.4	2.5	0.7	0.1	1.2	1.3	1.1	1.4	1.7	2.2	0.9
Medication: Aspirin	2.5	3.3	6.3	1.7	2.5	2.1	2.2	0.9	1.6	1.7	1.8	1.6	1.7	2.1	1.9	1.8	1.9	1.9	0.9	1.8	1.4	0.7	2.1	2.1	1.8	2.1	1.8	2.0	2.0
Medication: Aspirin	2.4	3.2	6.6	1.4	2.6	2.4	1.9	0.8	1.6	1.6	1.7	1.7	1.7	2.1	1.9	1.7	1.8	1.9	0.7	1.6	1.5	0.6	2.2	2.2	1.7	1.9	1.8	2.0	2.1
Illnesses of father: Heart disease	2.4	3.4	8.8	0.9	2.2	1.7	2.4	1.4	1.6	1.5	1.6	1.5	1.5	2.3	3.0	0.8	1.6	1.9	1.9	1.4	0.3	0.3	2.3	1.8	2.3	2.2	1.9	2.0	2.4
Hearing aid user	2.2	2.5	4.9	0.7	1.6	1.4	1.6	2.2	1.6	1.1	1.4	1.6	1.6	2.0	0.7	0.7	1.6	1.9	1.7	1.6	1.7	0.6	1.9	1.5	1.4	1.8	1.5	1.9	1.7
Glaucoma (self-reported)	2.1	2.5	5.4	1.4	2.0	1.2	1.9	0.9	1.6	2.3	2.1	1.4	1.6	1.8	0.1	1.4	1.8	1.8	0.8	1.9	1.5	0.3	1.5	1.8	0.0	1.9	1.6	1.8	1.7
Number of treatments/medications taken	1.9	3.4	8.8	3.0	1.9	1.0	1.7	2.0	1.6	0.7	1.2	1.8	1.7	2.5	1.3	1.0	1.8	2.2	1.6	1.9	0.2	-0.2	2.3	1.8	3.0	1.9	1.9	2.2	2.2
Length of working week for main job	1.9	2.1	3.8	-0.0	1.9	1.7	1.4	1.2	1.5	1.1	1.3	1.6	1.5	1.7	1.3	1.1	1.4	1.6	1.2	1.3	1.2	-0.1	1.9	1.5	1.5	1.6	1.6	1.7	1.6
Had other major operations	1.8	2.2	7.3	0.2	-0.0	0.0	1.0	0.4	2.1	2.7	2.5	0.8	2.1	0.5	-0.3	1.3	2.2	1.6	2.4	2.6	0.3	1.4	-0.0	1.2	0.2	1.6	1.6	1.3	-0.3
Medication for hormone replacement therapy	1.7	1.9	5.6	0.7	2.0	2.4	1.4	1.4	1.1	1.2	1.2	1.0	1.1	1.5	1.4	1.0	1.3	1.4	1.4	1.2	1.4	1.1	1.5	1.3	0.9	1.5	1.4	1.4	1.5
Taking other prescription medications	1.7	2.6	7.9	1.4	1.6	0.8	0.8	0.3	1.7	1.4	1.6	1.6	1.8	1.8	0.8	1.0	2.0	1.9	1.4	1.9	0.6	0.4	1.8	1.9	2.8	1.8	2.1	1.8	1.7
Prostate Cancer	1.6	2.3	18.0	4.2	2.0	1.2	1.7	1.6	0.7	1.2	1.2	0.2	0.8	1.8	1.5	-1.2	1.1	1.4	-0.7	1.0	0.1	0.6	1.2	0.6	1.9	2.0	0.7	1.4	1.4
Ever used hormone-replacement therapy (HRT)	1.6	2.0	4.1	0.2	-1.9	-2.0	-0.4	-0.3	-1.4	-1.2	-1.3	-1.7	-1.5	-1.6	-1.2	-0.8	-1.2	-1.6	-0.4	-1.0	-1.8	0.7	-1.8	-2.0	-1.7	-1.7	-1.7	-1.6	-1.7
Waist circumference	1.6	5.7	9.7	0.8	2.7	2.4	2.2	1.2	3.1	3.1	3.1	2.4	3.0	2.6	1.7	1.8	3.0	3.0	1.5	3.0	1.0	0.9	2.2	2.7	0.6	2.5	3.0	2.9	2.0
Neck or shoulder pain in last month	1.6	2.2	4.2	0.8	1.8	1.5	1.0	0.8	1.4	1.2	1.4	2.1	1.5	1.7	1.6	2.0	1.4	1.6	1.9	1.4	1.4	-0.0	1.8	1.5	2.0	1.1	1.6	1.6	1.5
Had major operations	1.6	1.9	16.2	3.8	1.6	0.7	2.0	0.8	-0.2	0.8	0.4	-0.6	-0.2	0.8	0.5	-0.2	0.2	0.3	0.9	0.1	0.6	0.4	0.7	0.8	4.0	2.0	0.5	0.3	1.5
Number of self-reported non-cancer illnesses	1.6	2.8	14.9	3.9	1.4	1.2	2.5	2.5	1.4	1.0	1.1	0.5	1.3	1.4	1.7	0.2	1.3	1.5	1.8	1.4	-0.2	1.5	1.0	0.6	3.2	1.6	1.3	1.4	0.8
HDL Cholesterol	1.5	2.6	7.8	-0.3	0.2	1.5	1.4	2.5	2.8	1.1	0.8	2.3	2.2	1.6	1.6	2.0	2.0	2.1	1.7	2.3	0.3	1.7	0.6	-0.2	-1.0	-0.5	0.9	2.2	-0.9
Arm fat percentage (right)	1.5	6.0	10.0	2.0	3.1	3.0	3.1	1.4	2.6	3.0	2.8	1.7	2.5	2.6	2.6	1.6	2.6	2.7	2.1	2.5	1.2	1.5	2.2	2.6	2.0	3.2	2.8	2.6	2.3
Prospective memory result	1.5	1.9	5.7	-0.8	1.2	1.2	0.8	1.4	1.1	0.7	1.0	2.1	1.2	1.7	2.4	1.5	0.8	1.4	2.1	1.2	1.3	-1.5	1.7	1.2	0.6	0.6	1.3	1.5	1.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.5	1.8	3.3	0.3	-1.7	-1.2	-1.8	-0.9	-1.3	-1.6	-1.6	-1.2	-1.3	-1.5	-0.5	-1.4	-1.4	-1.4	-1.2	-1.3	-1.0	-0.1	-1.7	-1.7	0.2	-1.7	-1.2	-1.5	-1.5
Osteoporosis (self-reported)	1.5	1.8	6.2	0.7	1.2	1.6	1.5	2.0	1.0	1.7	1.4	0.8	1.0	1.2	1.4	1.6	1.1	1.2	2.5	1.0	1.5	0.6	0.8	1.3	0.3	1.8	1.2	1.2	1.2
Risk taking	1.5	2.2	5.2	1.5	0.7	0.8	1.9	2.3	2.0	1.7	1.8	1.6	1.9	1.6	-0.0	1.2	1.9	1.9	1.8	2.1	0.5	0.1	0.9	0.9	0.6	1.4	1.2	1.8	0.6
Fasting Glucose	1.4	1.6	4.2	-0.5	0.8	-0.3	0.6	0.6	1.8	1.3	1.7	1.5	2.0	1.4	0.9	0.3	2.0	1.7	0.8	2.0	-0.2	0.2	1.2	1.5	0.1	1.3	1.7	1.7	0.9
Hair/balding pattern: Pattern 2	1.4	1.8	3.9	-0.4	-1.4	-1.4	-0.5	-0.8	-1.9	-1.5	-1.6	-1.5	-1.9	-1.3	-1.5	-1.4	-2.0	-1.7	-0.9	-1.8	-0.6	-0.5	-1.3	-1.4	0.3	-1.2	-1.6	-1.7	-0.8
Gout (self-reported)	1.4	1.9	5.7	2.0	-0.7	-0.7	0.3	-1.2	-1.2	-0.6	-1.0	-2.4	-1.4	-1.2	-1.6	-1.2	-0.9	-1.2	-1.6	-1.2	-2.0	2.3	-1.7	-1.4	0.3	0.3	-1.5	-1.3	-1.3
Ever taken oral contraceptive pill	1.4	1.5	3.4	-0.7	-1.5	-0.9	-0.5	0.1	-1.2	-1.2	-1.2	-1.6	-1.2	-1.6	-0.4	-1.2	-1.3	-1.5	-0.4	-1.3	-1.6	0.9	-1.3	-1.6	-0.4	-1.2	-1.6	-1.5	-1.8
Alcohol drinker status: Previous	1.4	1.7	5.3	1.3	0.9	0.3	1.8	1.3	1.3	2.1	1.8	0.4	1.3	0.5	-0.7	2.3	1.8	1.1	1.4	1.9	0.3	1.8	0.3	0.6	0.9	1.2	0.6	1.0	-0.3
Pack years of smoking	1.4	2.1	7.0	0.4	-2.6	-2.3	-1.6	-0.1	-0.7	-0.8	-0.8	-0.9	-0.7	-1.7	-2.1	0.7	-0.8	-1.1	-0.5	-0.2	-0.5	-0.9	-2.4	-1.8	-1.9	-2.0	-1.6	-1.2	-2.4
Pack years adult smoking proportion	1.3	2.0	5.9	0.7	-2.4	-2.0	-1.3	0.0	-1.0	-0.9	-0.9	-1.2	-0.9	-1.7	-2.0	0.6	-1.0	-1.2	-0.5	-0.4	-0.3	-0.5	-2.4	-1.9	-1.7	-1.8	-1.7	-1.4	-2.3
Trunk fat percentage	1.3	5.1	8.7	1.1	2.9	2.8	2.0	0.6	2.7	2.7	2.6	2.2	2.6	2.7	2.1	1.2	2.5	2.9	1.4	2.6	1.1	0.5	2.3	2.8	0.7	2.5	2.9	2.8	2.4
Serious illness, injury or assault to yourself	1.3	1.5	5.8	1.6	1.7	1.6	1.9	1.2	0.1	1.0	0.8	-0.0	0.2	1.2	0.7	0.7	0.2	0.6	2.3	0.3	1.2	0.4	0.9	1.2	1.7	2.4	0.8	0.8	1.8
Cholesterol lowering medication	1.3	2.0	4.8	0.8	-1.5	-1.7	-0.4	-0.8	-1.4	-1.7	-1.7	-1.8	-1.4	-1.4	-1.5	-0.3	-1.2	-1.5	-0.7	-1.1	-2.2	0.9	-1.6	-1.9	-0.5	-1.2	-1.9	-1.5	-1.7
Basal cell carcinoma (self-reported)	1.3	1.5	4.8	-0.7	-1.6	-2.2	-1.1	-1.1	-1.1	-1.0	-1.1	-1.5	-1.1	-1.8	-1.7	-0.2	-0.9	-1.4	-1.0	-0.9	-0.9	0.4	-1.5	-1.1	-0.6	-0.8	-1.2	-1.5	-1.6
Depression (Nagel 2018)	1.2	1.8	3.8	0.6	-1.0	-0.0	-0.2	1.0	-1.8	-1.9	-1.8	-1.4	-1.8	-1.2	-1.3	-0.7	-1.7	-1.7	0.3	-1.8	-1.0	-0.3	-1.1	-1.9	1.6	-1.3	-1.9	-1.6	-0.9
Breast Cancer	1.2	2.9	6.8	-0.2	1.8	0.8	0.5	-0.8	1.4	1.5	2.1	1.8	1.9	2.0	1.5	0.4	1.7	1.8	1.3	1.5	1.7	-0.0	2.1	2.6	1.9	2.5	2.2	1.9	2.5
Medication: Co-codamol	1.2	1.3	5.9	1.3	0.6	1.4	1.3	2.4	0.9	0.9	0.9	1.1	0.9	1.2	1.8	1.4	0.8	1.1	2.1	1.0	0.9	0.5	0.9	0.6	0.7	0.6	0.7	1.2	0.7
Current tobacco smoking	1.2	2.0	4.7	1.0	-1.8	-2.2	-0.4	-0.1	-1.4	-1.0	-1.3	-2.1	-1.5	-1.7	-2.2	-0.7	-1.2	-1.6	-0.7	-1.0	-1.4	0.6	-1.8	-1.7	-0.8	-0.9	-1.7	-1.7	-1.7
Frequency of unenthusiasm / disinterest in last 2 weeks	1.2	1.6	4.1	1.3	-0.4	-0.0	-0.0	0.4	-1.8	-2.0	-2.0	-1.4	-1.9	-0.5	-0.6	-1.1	-1.9	-1.4	-0.4	-1.9	-0.9	0.0	-0.5	-1.7	2.0	-0.7	-1.7	-1.2	-0.2
Hip circumference	1.2	5.0	8.2	1.2	2.8	2.9	2.6	1.1	2.5	2.6	2.5	1.8	2.4	2.1	2.6	2.0	2.5	2.5	2.0	2.4	1.2	0.7	2.1	2.3	2.1	2.5	2.8	2.4	1.9
Alcohol intake versus 10 years previously	1.2	1.8	5.6	1.1	0.7	0.9	2.4	1.0	1.7	1.4	1.4	1.0	1.6	1.5	1.0	1.6	1.6	1.6	1.6	1.6	0.5	2.2	0.6	0.6	-0.5	1.8	0.8	1.6	0.5
Worrier / anxious feelings	1.2	2.2	9.1	0.1	-1.7	-1.2	-1.2	-2.3	-1.4	-1.7	-1.6	-0.9	-1.5	-0.8	-0.4	-1.6	-1.7	-1.2	-3.0	-1.4	-1.5	-0.9	-1.8	-1.7	-1.2	-1.6	-1.5	-1.2	-0.8
Medication for cholesterol, blood pressure or diabetes	1.2	1.9	11.6	-3.4	-0.2	-0.5	-2.2	-1.9	-1.5	-1.2	-1.2	-0.2	-1.3	-0.9	-0.6	-0.8	-1.5	-1.4	-0.5	-1.7	0.4	-3.0	0.0	-0.1	-1.0	-1.3	-0.7	-1.2	0.2
Body fat percentage	1.2	4.8	8.0	1.0	2.8	2.5	2.2	0.9	2.6	2.5	2.5	2.1	2.5	2.6	2.1	1.2	2.4	2.7	1.4	2.4	1.0	0.7	2.3	2.6	1.0	2.4	2.8	2.7	2.3
Mouth/teeth dental problems: Loose teeth	1.2	1.5	3.0	-0.2	-1.3	-1.4	-1.7	-1.1	-1.5	-1.7	-1.7	-1.2	-1.5	-1.2	-1.1	-1.0	-1.6	-1.4	-0.3	-1.3	0.2	-0.8	-1.3	-1.0	-0.6	-0.9	-1.3	-1.4	-0.9
Arm fat percentage (left)	1.2	4.7	8.6	1.6	2.9	2.7	2.6	1.1	2.4	2.7	2.5	1.4	2.3	2.3	2.0	1.1	2.3	2.4	1.5	2.2	1.0	1.6	2.0	2.3	1.7	2.9	2.5	2.4	2.0
Medication: Blood pressure	1.2	2.3	9.4	3.1	1.6	2.4	2.5	0.9	1.5	0.8	1.0	0.4	1.4	1.5	2.4	1.1	1.3	1.6	0.9	1.3	0.3	2.4	0.8	0.4	0.7	1.5	0.7	1.5	0.5
Heart disease (siblings)	1.2	1.5	5.7	0.4	1.7	1.6	1.0	-0.2	0.3	0.5	0.4	1.5	0.4	1.4	2.4	1.3	0.3	0.9	0.7	0.1	1.8	-0.8	1.5	1.2	2.0	0.8	1.2	0.9	2.0
HbA1C	1.1	1.2	5.1	1.0	-0.6	-1.0	-0.4	-0.6	-0.7	0.3	0.7	-1.2	-0.4	-1.5	-1.3	-1.3	0.2	-0.6	-2.0	-0.3	-2.2	1.4	-1.0	-0.6	-1.6	-0.8	-0.6	-1.2	-1.2
Trunk fat mass	1.1	4.6	7.7	0.9	2.7	2.8	2.0	0.6	2.5	2.6	2.5	1.9	2.4	2.4	2.1	1.3	2.4	2.6	1.5	2.4	1.0	0.7	2.1	2.5	1.2	2.4	2.8	2.5	2.1
Mouth/teeth dental problems	1.1	1.7	3.6	-1.4	-0.7	-0.5	-0.8	-1.2	-1.6	-1.9	-1.8	-1.3	-1.6	-1.2	-1.0	-1.1	-1.7	-1.6	-1.4	-1.8	-1.4	0.1	-0.6	-1.5	0.3	-1.0	-1.5	-1.4	-0.8
Arm fat mass (right)	1.1	4.4	7.1	1.4	2.6	2.7	2.7	1.5	2.4	2.5	2.4	1.5	2.3	2.0	2.3	1.4	2.4	2.3	1.9	2.2	0.8	1.5	1.9	2.1	2.0	2.5	2.5	2.2	1.7
Whole body fat mass	1.1	4.5	7.5	1.0	2.7	2.6	2.2	1.0	2.5	2.5	2.4	1.8	2.4	2.3	2.0	1.2	2.4	2.5	1.5	2.3	0.9	0.9	2.1	2.4	1.6	2.4	2.7	2.5	2.0
Diabetes diagnosed by doctor	1.1	1.8	5.7	1.8	2.0	1.7	1.7	1.3	0.7	1.1	1.0	0.5	0.7	1.4	0.6	0.8	0.9	1.0	0.9	0.8	1.3	0.5	1.6	1.4	2.4	1.9	1.1	1.1	1.6
Smoking status: Current	1.1	1.8	4.6	0.7	-1.6	-2.1	-0.7	-0.0	-1.4	-1.2	-1.4	-1.9	-1.5	-1.6	-2.2	-0.9	-1.3	-1.5	-0.6	-1.1	-1.0	0.3	-1.5	-1.5	-0.7	-0.9	-1.6	-1.6	-1.4
Arm fat mass (left)	1.1	4.6	7.8	1.2	2.7	2.8	2.6	1.2	2.4	2.6	2.5	1.5	2.3	2.1	2.2	1.4	2.3	2.4	1.8	2.2	1.1	1.4	1.9	2.3	1.9	2.7	2.6	2.3	1.8
Number of operations (self-reported)	1.1	1.6	6.5	1.9	0.6	0.9	1.8	0.4	1.1	1.7	1.5	0.2	1.1	1.0	1.5	0.9	1.4	1.2	1.8	1.5	-0.3	0.9	0.4	0.7	2.5	1.8	1.0	1.0	0.6
Myopia	1.1	1.6	7.3	-0.0	1.0	2.4	1.2	1.2	0.7	1.1	0.9	0.6	0.7	0.5	2.3	1.2	0.6	0.7	2.7	0.5	2.5	0.9	0.7	0.7	1.8	0.8	1.0	0.7	0.5
Alzheimer’s Disease (in mother)	1.0	1.2	2.8	-0.1	1.1	0.4	1.0	0.1	1.1	0.9	1.0	1.3	1.1	1.7	1.4	0.0	1.3	1.4	0.8	1.1	0.2	0.4	1.6	1.2	0.2	1.4	1.2	1.5	1.5
Crohns Disease (2012)	1.0	1.6	5.8	0.2	1.5	0.2	1.5	0.8	1.3	1.5	1.2	0.6	1.2	1.4	-0.3	-0.5	1.7	1.4	-0.1	1.2	-0.2	0.7	1.6	1.9	0.9	2.4	1.5	1.5	1.7
Lung FVC	1.0	5.2	10.5	-1.3	-2.5	-1.0	-3.2	-1.5	-2.7	-3.2	-3.1	-2.1	-2.6	-2.3	-0.5	-1.2	-3.2	-2.7	-1.0	-2.8	-0.2	-2.0	-2.4	-2.5	-1.3	-2.6	-2.6	-2.6	-1.7
Chronotype (morning person)	1.0	2.4	5.4	-0.4	0.9	0.6	0.0	1.2	2.2	1.7	2.0	1.9	2.3	1.2	0.5	1.0	2.1	2.0	2.3	2.3	0.6	0.8	1.3	1.8	0.8	1.2	2.2	1.8	0.6
Ever had hysterectomy (womb removed)	1.0	1.1	7.5	0.8	2.0	2.7	1.7	1.2	-0.3	-0.5	-0.4	0.6	-0.3	1.2	1.5	-0.2	-0.3	0.3	0.9	-0.7	0.9	-0.0	1.4	0.5	0.5	0.2	0.3	0.5	1.7
Diabetes (mother)	1.0	1.2	3.5	-0.0	1.0	0.3	0.5	0.7	1.2	1.5	1.5	0.6	1.3	0.5	0.1	1.2	1.2	0.9	0.7	1.2	1.8	0.7	0.7	1.6	1.3	1.9	1.7	0.9	0.8
Severe depression (siblings)	1.0	1.1	3.4	-0.0	1.6	1.8	0.7	0.7	0.8	0.8	0.7	1.3	0.7	1.4	1.8	1.0	0.6	1.1	1.0	0.7	0.7	-0.9	1.5	0.8	0.8	0.3	1.1	1.2	1.4
Medication: Cholesterol lowering	1.0	1.5	8.7	3.0	0.0	0.8	2.5	1.9	1.2	1.1	1.1	0.3	1.1	1.1	1.0	0.8	1.2	1.2	0.6	1.4	-0.5	2.0	-0.2	-0.0	1.0	1.0	0.4	1.1	0.0
Qualifications: O levels/GCSEs or equivalent	1.0	1.5	4.4	-2.1	-0.6	-0.1	-1.7	-0.1	-1.4	-0.7	-0.9	-0.9	-1.3	-1.9	-1.1	0.1	-1.4	-1.8	-0.6	-1.5	0.4	-1.2	-1.0	-1.2	-1.1	-1.7	-1.2	-1.7	-1.2
Medication: Amlodipine	1.0	1.4	3.0	1.3	0.9	1.7	1.2	1.1	1.5	0.9	1.0	0.7	1.4	1.4	1.2	1.3	1.2	1.5	1.4	1.4	0.7	0.9	0.9	0.7	0.6	1.0	1.2	1.5	0.9
Medication: Ventolin 100micrograms inhaler	1.0	1.3	2.3	0.3	-1.2	-0.9	-0.3	-0.2	-1.2	-1.5	-1.5	-1.2	-1.3	-1.3	-1.2	-0.4	-1.3	-1.4	-1.1	-1.4	-1.4	-0.4	-1.3	-1.4	-0.3	-1.2	-1.4	-1.4	-1.1
Birth weight	1.0	2.2	6.8	-1.9	-2.1	-1.7	-1.8	-1.0	-1.1	-1.7	-1.5	-0.5	-1.1	-1.7	-0.2	-0.5	-1.4	-1.4	-0.9	-1.1	-0.9	-1.2	-1.3	-1.6	-1.9	-2.6	-1.2	-1.5	-1.9
Heart disease (mother)	1.0	1.2	9.2	3.0	1.4	0.9	1.4	0.1	-1.2	-0.4	-0.7	-1.2	-1.1	0.4	0.8	-0.2	-0.8	-0.4	0.6	-0.9	-0.2	-0.1	0.2	0.5	2.1	1.5	0.0	-0.4	1.5
Handedness (chirality/laterality): Left-handed	1.0	1.2	2.7	1.2	0.5	0.6	1.4	0.8	1.6	0.4	0.9	0.6	1.6	1.1	1.4	-0.2	1.4	1.5	0.1	1.4	-0.4	1.5	0.9	0.4	1.4	1.3	0.9	1.4	0.1
Osteoarthritis (self-reported)	1.0	1.3	3.0	-0.7	0.6	0.8	0.2	-0.3	1.5	1.1	1.2	1.7	1.5	1.5	0.9	0.4	1.2	1.6	-0.1	1.3	1.0	-0.7	0.9	1.4	0.7	1.1	1.6	1.5	1.3
Miserableness	1.0	1.7	5.6	2.3	0.1	0.7	0.7	0.9	-1.5	-2.4	-2.1	-0.7	-1.5	0.2	1.4	-0.9	-1.7	-0.8	0.6	-1.4	-1.1	-1.2	0.0	-1.5	2.3	-0.7	-1.4	-0.7	0.3
Pain type(s) experienced in last month: Hip pain	1.0	1.3	4.7	-0.4	0.1	-0.4	-1.0	-2.1	-1.3	-1.5	-1.4	-0.4	-1.2	0.1	0.5	-1.1	-1.4	-0.8	-2.0	-1.3	-1.7	-2.2	0.4	-0.5	0.4	-0.5	-0.6	-0.6	0.8
Medication: Atorvastatin	1.0	1.2	15.3	3.9	-0.1	0.8	1.2	0.6	-0.8	-0.7	-0.7	-1.3	-0.8	-0.2	1.0	0.4	-0.8	-0.5	0.2	-0.4	-1.1	1.3	-1.0	-1.3	0.6	-0.2	-1.1	-0.5	-0.7
Intelligence (Savage-Jansen 2018)	0.9	2.8	9.5	-2.1	1.4	0.5	-0.3	-1.3	1.1	1.6	1.4	1.7	1.2	1.6	1.4	0.1	0.6	1.3	0.3	0.6	3.1	-2.0	1.7	2.9	0.7	2.4	2.3	1.5	2.9
Alzheimer’s Disease (in father)	0.9	0.9	3.7	-1.7	0.2	0.1	-1.3	-0.8	1.3	0.3	0.7	1.5	1.3	0.8	0.5	-0.5	1.0	1.1	-0.9	0.8	0.4	0.0	0.8	0.9	-1.9	-0.2	1.1	1.1	0.4
Alzheimer’s Disease (including proxy)	0.9	1.2	2.9	-1.2	0.6	0.1	0.1	-0.7	1.4	0.7	1.1	1.7	1.4	1.6	1.2	-0.4	1.4	1.5	0.0	1.2	0.1	-0.1	1.3	1.3	-1.4	0.8	1.3	1.6	1.2
Hand grip strength (left)	0.9	2.3	8.2	-0.5	-1.5	-0.9	-0.3	0.4	-1.4	-2.0	-1.9	-1.3	-1.5	-1.4	-0.1	-1.2	-1.4	-1.5	-1.4	-1.5	-2.9	0.0	-1.0	-2.2	-0.6	-2.4	-2.1	-1.5	-1.9
Relative age of first facial hair	0.9	1.8	6.3	-2.5	1.3	0.8	-0.6	-0.9	1.0	0.9	0.9	1.9	1.1	1.3	1.7	0.8	0.8	1.1	0.0	0.8	2.5	-1.5	1.7	1.8	-0.7	0.5	1.5	1.3	1.7
Diverticular disease/diverticulitis (self-reported)	0.9	1.0	3.7	-0.7	-1.4	-1.4	-1.8	-1.9	-0.7	-0.3	-0.4	-0.8	-0.6	-1.5	-0.7	-0.6	-0.6	-1.0	-0.8	-0.8	-0.7	0.1	-1.3	-0.6	-0.5	-0.9	-0.7	-1.2	-1.3
Had menopause	0.9	1.2	4.1	-0.4	-0.5	-0.4	0.0	0.2	1.4	1.5	1.5	1.3	1.4	0.6	0.9	2.0	1.3	1.1	1.2	1.7	1.1	-0.8	0.1	0.8	-1.4	0.2	1.2	1.1	0.1
Illnesses of siblings	0.9	1.2	3.2	-1.3	-1.3	-1.8	-1.1	-0.6	-0.7	-1.0	-1.0	-0.9	-0.8	-1.5	-1.1	-1.4	-0.7	-1.1	-0.7	-0.7	-1.0	-0.1	-1.0	-1.0	-1.1	-1.6	-1.1	-1.2	-1.7
Pulse rate	0.9	1.6	4.3	1.6	1.0	0.8	0.5	0.1	1.2	0.9	1.1	1.3	1.2	2.1	1.1	0.8	1.0	1.6	0.3	1.3	1.7	-0.4	1.2	1.4	0.5	1.4	1.3	1.7	2.0
Medication: Paracetamol	0.9	1.4	8.3	-1.2	-0.9	-0.8	-1.4	-0.1	-1.0	-2.2	-1.8	0.6	-1.0	-0.2	0.8	-0.9	-1.3	-0.7	-0.1	-1.2	-1.0	-2.9	0.1	-0.9	1.0	-2.1	-0.7	-0.6	0.0
Leg fat percentage (right)	0.9	3.2	5.2	1.0	2.3	1.9	2.3	1.1	2.0	1.9	1.9	1.5	1.9	2.1	1.7	0.8	1.8	2.2	1.2	1.8	0.6	0.8	1.8	2.1	1.3	2.1	2.2	2.1	1.9
Wheeze or whistling in the chest in last year	0.9	1.6	4.0	-0.7	0.7	-0.0	0.9	1.5	1.7	0.9	1.2	2.0	1.6	1.6	0.2	0.3	1.8	1.6	0.5	1.4	-0.5	-0.4	1.9	1.7	0.8	0.8	1.7	1.7	1.4
Medication: Allopurinol	0.9	1.3	2.7	1.1	-1.0	-0.8	-0.4	0.2	-1.1	-1.4	-1.5	-1.6	-1.2	-1.1	-1.1	-1.4	-1.3	-1.1	-0.9	-1.1	-1.5	0.4	-1.3	-1.3	0.0	-0.6	-1.2	-1.2	-1.2
Leg fat mass (right)	0.9	3.5	5.7	0.9	2.2	2.2	2.1	1.1	2.3	2.0	2.0	1.6	2.1	2.1	2.0	0.8	2.1	2.3	1.3	1.9	0.7	1.1	1.9	2.1	1.5	2.2	2.4	2.2	1.8
Medication: Bendroflumethiazide	0.9	1.3	4.6	2.2	1.0	1.3	0.8	0.8	1.7	1.2	1.5	0.9	1.7	0.9	0.7	0.7	1.8	1.5	-0.0	1.6	-0.5	1.6	0.5	0.6	-0.2	0.7	1.0	1.3	0.0
Medication: Paracetamol	0.9	1.4	5.9	-0.8	-0.8	-0.8	-1.3	0.5	-1.1	-2.2	-1.9	-0.1	-1.1	-0.5	-0.1	-1.2	-1.3	-0.9	-0.3	-1.1	-1.4	-2.4	-0.0	-1.0	1.4	-1.8	-0.7	-0.8	-0.2
Ever depressed for a whole week	0.9	1.1	4.7	1.3	1.0	1.3	2.2	0.8	0.3	0.8	0.6	0.0	0.2	0.8	2.1	1.3	0.4	0.6	1.2	0.3	0.9	0.9	0.5	0.2	2.0	1.0	0.4	0.5	0.7
Unable to work because of sickness or disability	0.9	1.2	2.9	0.5	1.2	0.5	1.1	1.3	1.1	0.5	0.8	1.2	1.1	1.6	0.6	0.0	1.0	1.3	0.4	1.0	0.2	-0.2	1.7	1.3	1.4	1.4	1.2	1.4	1.6
Bipolar Disorder (2018)	0.8	1.3	3.3	0.8	-0.5	0.3	-0.9	-0.5	-1.4	-1.6	-1.8	-0.8	-1.5	0.1	-0.1	-1.8	-1.5	-0.7	-1.6	-1.5	-1.7	-1.1	-0.3	-1.1	-1.0	-0.9	-1.3	-0.6	0.3
Worry (Nagel 2018)	0.8	1.6	4.7	0.4	-0.9	-0.1	-1.4	-0.6	-1.4	-2.1	-2.0	-0.9	-1.5	-0.3	-0.1	-2.2	-1.6	-0.9	-2.0	-1.5	-1.1	-0.8	-1.0	-1.6	-0.1	-1.7	-1.4	-0.9	-0.3
Ovarian Cancer	0.8	1.0	4.1	-0.2	-0.5	-1.5	-0.8	0.3	-1.3	-1.5	-1.5	-1.0	-1.3	-1.0	-0.9	-2.0	-1.3	-1.2	-0.2	-1.3	-0.5	-0.7	-0.4	-0.6	0.0	-1.0	-0.7	-1.2	-0.4
Mean Putamen Volume	0.8	0.9	1.6	-0.1	1.2	0.4	0.9	-0.4	1.1	0.7	1.0	0.9	1.2	1.3	0.8	-0.0	1.2	1.2	0.2	1.2	-0.7	0.6	1.3	1.1	-0.1	1.2	1.3	1.2	1.1
Blood Eosinophil Count	0.8	6.0	11.5	0.3	1.6	0.4	1.8	1.8	3.3	3.2	3.4	2.4	3.4	1.9	0.6	1.3	3.3	2.9	2.2	3.2	2.3	2.1	2.1	3.2	1.2	3.2	3.4	2.7	1.4
Other serious medical condition/disability diagnosed by doctor	0.8	1.0	3.4	1.3	1.0	1.7	1.0	1.6	0.8	1.4	1.2	-0.3	0.8	0.2	0.2	0.5	0.9	0.6	1.8	1.0	0.1	1.9	-0.1	0.4	0.8	1.3	0.8	0.5	0.0
Body mass index (BMI)	0.8	3.5	5.9	1.2	2.2	2.0	2.2	1.1	2.2	2.1	2.1	1.3	2.1	2.0	1.7	0.5	2.1	2.2	1.2	1.9	0.8	1.6	1.8	2.0	2.0	2.4	2.4	2.1	1.7
Forced vital capacity (FVC)	0.8	3.2	12.2	-1.7	-1.6	-0.4	-3.5	-1.5	-1.7	-2.5	-2.2	-0.5	-1.6	-1.4	0.1	-0.9	-2.1	-1.7	-1.6	-1.9	-0.4	-3.0	-1.1	-1.5	-2.0	-2.7	-1.5	-1.5	-1.0
Financial difficulties in last 2 years	0.8	1.1	1.9	1.0	1.4	1.4	0.7	1.3	1.1	0.7	1.0	1.1	1.2	1.1	0.3	1.4	1.4	1.2	1.3	1.1	0.2	0.4	1.2	0.7	1.2	0.8	0.8	1.2	0.7
Diabetes (self-reported)	0.8	1.2	7.1	2.1	1.6	1.5	1.8	1.6	-0.4	0.1	0.0	-0.5	-0.4	0.5	0.6	0.5	-0.1	-0.1	0.9	-0.3	1.0	0.5	0.9	0.6	2.7	1.4	0.2	0.1	1.1
Frequency of tiredness / lethargy in last 2 weeks	0.8	1.3	4.6	1.8	0.2	0.2	-0.8	0.0	-1.6	-2.1	-1.8	-0.5	-1.5	0.6	0.1	-1.5	-1.7	-0.7	-1.1	-1.6	0.2	-1.4	0.2	-0.8	1.0	-0.4	-1.1	-0.4	1.1
Medication: Ibuprofen (e.g. Nurofen)	0.8	1.0	2.1	1.5	-0.2	0.0	0.0	1.0	-1.4	-1.5	-1.4	-0.7	-1.4	-0.3	0.4	-0.9	-1.2	-1.0	0.1	-1.4	-1.3	-0.7	-0.1	-1.2	1.0	-1.1	-1.2	-0.9	-0.1
Lung cancer (father)	0.8	0.9	5.2	-0.7	-1.1	-1.4	-0.5	-1.0	-0.5	0.4	0.1	-1.6	-0.6	-1.4	-2.3	-0.5	-0.2	-1.0	-1.5	-0.4	-0.6	1.1	-1.1	-0.3	0.2	0.3	-0.5	-1.0	-1.0
Exposure to tobacco smoke at home	0.8	0.9	1.8	1.0	0.1	0.6	0.3	1.2	1.3	0.7	1.1	1.2	1.3	1.1	0.8	1.0	1.1	1.3	1.3	1.3	0.8	-0.2	0.6	0.5	0.9	0.4	1.1	1.3	0.5
Pulse wave reflection index	0.8	1.0	2.9	-1.1	-0.4	-0.3	-0.4	0.1	-0.5	-0.4	-0.5	-0.9	-0.6	-1.3	-1.5	-1.4	-0.4	-0.9	-1.6	-0.8	-1.7	1.7	-0.6	-1.0	-0.3	-1.2	-0.8	-1.0	-1.5
Eye problems/disorders: None of the above	0.8	0.9	3.2	0.1	-1.7	-0.8	-1.1	-0.3	-0.5	-1.0	-0.9	-0.9	-0.5	-1.5	0.5	-0.3	-0.5	-0.8	-0.0	-0.5	-1.1	-0.7	-1.5	-1.3	-0.3	-1.5	-0.8	-1.1	-1.8
Qualifications: nursing, teaching	0.8	1.3	2.7	0.1	-0.5	-0.6	-0.3	1.2	-1.6	-1.2	-1.4	-1.6	-1.6	-1.6	-0.6	-0.9	-1.2	-1.6	-0.0	-1.2	-1.3	-0.7	-0.9	-1.2	-0.3	-0.8	-1.3	-1.6	-1.0
Eye problems/disorders: Cataract	0.8	1.0	4.1	-0.6	1.1	0.8	1.2	-0.6	0.3	-0.1	0.0	1.5	0.3	2.0	1.5	0.4	0.1	1.0	0.0	0.2	1.2	-0.1	1.7	1.0	-0.1	0.6	0.4	1.3	2.0
Average weekly champagne plus white wine intake	0.8	1.2	3.1	-0.3	0.1	1.1	-0.2	1.0	1.7	1.4	1.5	1.4	1.7	0.8	-0.5	0.8	1.4	1.4	1.0	1.6	1.2	0.2	0.3	1.1	-0.2	0.7	1.4	1.3	0.2
Mother’s age at death	0.8	0.9	6.0	0.2	-0.2	-0.4	1.1	0.4	0.5	1.5	1.2	-0.4	0.5	-0.9	-0.6	2.3	0.7	-0.1	2.4	0.8	0.3	1.6	-0.7	0.2	-0.2	0.7	0.2	-0.2	-1.1
Tinnitus: Yes, now most or all of the time	0.8	0.9	2.2	-0.7	1.0	0.9	0.4	0.5	1.1	0.9	1.0	1.0	1.1	0.8	0.1	0.6	1.0	1.0	0.7	0.7	1.5	0.6	1.0	1.5	1.1	1.2	1.3	1.0	0.9
Commuting to job workplace: Public transport	0.8	0.9	3.0	1.3	0.2	0.4	1.2	0.6	0.7	0.9	0.9	0.7	0.8	0.9	0.6	1.5	0.7	0.9	1.6	1.1	1.4	-0.8	0.1	0.8	0.3	1.7	0.7	0.9	0.9
Medication: Lisinopril	0.8	1.0	3.0	0.7	-0.8	-0.9	0.1	-1.3	-0.7	-0.6	-0.7	-1.3	-0.8	-1.3	0.2	-0.7	-0.8	-1.0	-1.2	-0.7	-1.4	1.3	-1.1	-1.5	0.0	-1.1	-1.1	-1.2	-1.7
Alcohol drinker status: Never	0.8	1.0	5.9	-0.4	-0.1	-0.1	-1.9	-0.2	-0.6	-1.1	-1.0	-1.0	-0.7	-1.3	-0.7	-2.4	-0.7	-0.9	-1.1	-1.2	-0.3	-0.6	-0.1	-0.4	1.6	-0.9	-0.3	-1.0	-0.8
Leg fat mass (left)	0.8	3.1	5.1	0.8	2.1	2.0	2.0	0.9	2.2	2.0	2.0	1.6	2.0	2.1	1.9	0.8	2.0	2.2	1.1	1.8	0.6	1.1	1.8	2.0	1.3	2.0	2.3	2.1	1.7
Ulcerative Colitis (UC)	0.7	1.4	7.4	2.3	0.3	0.3	2.7	2.0	0.5	0.7	0.7	-0.6	0.5	0.0	0.1	0.6	1.3	0.5	1.1	0.8	-1.7	2.3	-0.1	-0.1	1.6	1.5	0.1	0.2	-0.4
Qualifications: None of the above	0.7	1.5	3.5	1.3	1.0	0.6	0.9	1.0	1.3	0.6	0.8	1.4	1.2	1.9	1.4	0.5	1.1	1.7	0.9	1.3	0.5	-0.5	1.5	1.5	1.0	1.0	1.4	1.7	1.6
Weight	0.7	3.2	6.2	0.5	2.3	2.5	1.7	0.9	2.1	2.1	2.0	1.5	2.0	1.7	2.0	1.2	1.9	2.0	1.4	1.8	1.0	0.8	1.8	2.0	1.8	1.9	2.4	1.9	1.6
Hair/balding pattern: Pattern 3	0.7	1.0	2.9	-1.1	1.0	0.6	-0.1	-0.5	1.4	0.6	1.0	1.0	1.4	0.8	1.3	-0.5	1.3	1.2	0.3	1.0	-0.8	-0.0	1.3	1.2	0.7	1.0	1.7	1.1	0.8
Qualifications: A levels/AS levels or equivalent	0.7	1.5	4.4	-1.9	-0.4	-0.4	-1.1	-0.6	-1.6	-0.4	-0.8	-1.1	-1.6	-2.1	-0.5	0.2	-1.6	-2.0	-0.2	-1.6	-0.5	-0.9	-1.0	-1.0	-0.8	-1.5	-1.1	-2.0	-1.2
Worry too long after embarrassment	0.7	1.2	5.5	0.7	0.1	0.3	0.2	0.7	-1.3	-1.7	-1.6	-1.0	-1.3	-0.1	0.1	-2.4	-1.5	-0.8	-1.3	-1.5	-1.9	0.6	-0.2	-1.2	0.7	-0.3	-1.0	-0.7	0.2
Medication: Blood pressure	0.7	1.3	8.1	2.8	-0.0	-0.1	0.9	1.1	1.5	1.6	1.5	0.2	1.5	0.5	0.1	1.1	1.6	1.2	0.3	1.8	0.1	1.5	-0.1	0.5	0.5	1.2	1.1	1.0	-0.2
Family relationship satisfaction	0.7	0.8	3.3	0.9	-0.3	-0.6	-0.4	-0.8	-1.3	-1.1	-1.1	-0.9	-1.2	-0.6	-1.5	-0.8	-1.4	-1.0	-0.1	-1.0	0.3	-1.8	-0.7	-0.6	-0.6	-0.4	-0.8	-1.0	0.1
Illness, injury, bereavement, stress in last 2 years	0.7	0.8	4.9	0.3	-1.2	-1.4	-0.9	-1.3	-0.8	-0.6	-0.8	-0.7	-0.8	-0.8	-0.2	-1.3	-0.8	-0.8	-2.2	-0.8	-0.5	-0.3	-0.8	-0.7	0.1	-0.9	-0.7	-0.8	-0.5
Hypertension (Self-reported)	0.7	1.9	11.1	3.3	1.3	1.5	2.2	2.2	1.2	0.9	1.0	0.2	1.1	1.2	1.2	0.7	1.1	1.3	0.9	1.1	0.3	2.0	0.7	0.3	1.3	1.4	0.8	1.2	0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.7	0.9	1.9	0.6	0.1	0.0	-0.2	-0.7	1.3	1.1	1.2	1.1	1.3	1.1	-0.5	0.3	1.1	1.3	-0.3	1.3	0.9	-0.5	0.1	1.3	-0.0	0.9	1.4	1.3	0.8
Back pain experienced in last month	0.7	1.0	3.9	0.8	-0.0	-0.6	-1.5	-0.3	-0.9	-1.7	-1.4	-0.2	-0.9	-0.4	-0.3	-1.0	-1.2	-0.6	-1.3	-0.9	-1.1	-2.0	0.0	-0.7	-0.3	-1.9	-0.4	-0.7	-0.1
Wears glasses or contact lenses	0.7	0.8	3.2	0.5	1.0	1.0	0.9	0.8	0.3	1.0	0.7	0.0	0.3	0.1	0.3	1.5	0.5	0.3	1.6	0.3	1.7	0.4	0.3	0.9	1.8	1.4	0.9	0.3	0.7
Supplements: Fish oil (including cod liver oil)	0.7	1.0	2.8	-1.7	-0.2	-0.3	-1.2	-0.8	-1.2	-1.0	-1.1	-1.3	-1.2	-1.3	-1.5	0.1	-1.2	-1.4	0.0	-1.3	-0.3	0.4	-0.5	-0.7	-0.2	-0.4	-0.9	-1.3	-0.7
High cholesterol (Self-reported)	0.7	1.3	6.1	2.5	-1.8	-0.8	0.2	-0.0	-0.5	-0.3	-0.4	-1.3	-0.5	-0.8	-0.5	0.7	-0.3	-0.6	-0.2	0.0	-1.5	1.7	-2.1	-1.8	-0.5	-0.5	-1.4	-0.7	-1.7
Ever smoked	0.7	1.2	3.2	0.8	-1.0	-1.0	0.2	-1.4	-1.1	-0.7	-1.1	-1.7	-1.3	-1.2	-1.8	-0.2	-1.1	-1.2	0.2	-1.0	-1.4	0.3	-1.4	-1.2	-0.4	-0.1	-1.4	-1.2	-1.0
Leg fat percentage (left)	0.7	2.7	4.4	0.6	2.1	1.8	2.0	0.7	2.0	1.8	1.8	1.6	1.9	2.1	1.5	0.7	1.8	2.1	0.9	1.8	0.5	0.8	1.7	2.0	0.7	1.8	2.1	2.0	1.8
Irritability	0.7	1.1	2.7	0.8	-0.9	-0.2	-0.3	0.4	-1.5	-1.6	-1.6	-1.2	-1.5	-0.7	0.2	-1.3	-1.6	-1.2	-0.2	-1.6	-0.9	-0.3	-1.1	-1.3	1.0	-0.4	-1.3	-1.1	-0.3
Irritable Bowel Disease (IBD)	0.6	1.4	7.3	2.6	0.0	-0.4	2.3	1.5	0.4	0.8	0.6	-1.0	0.4	0.0	-0.7	-0.0	1.2	0.4	0.2	0.8	-1.8	2.7	-0.3	-0.0	1.2	1.9	-0.0	0.2	-0.3
Major Depression (MDD)	0.6	0.7	2.5	-0.7	0.2	1.0	0.9	0.2	-1.1	-0.9	-1.0	0.1	-1.1	0.1	1.2	1.6	-0.8	-0.7	1.2	-0.9	0.8	-0.7	0.3	-0.7	0.4	-0.9	-1.0	-0.5	0.4
Age at First Birth	0.6	0.9	4.7	1.2	0.3	0.1	0.7	-0.8	0.4	1.3	1.1	-0.2	0.6	0.2	0.3	0.4	0.6	0.4	1.1	0.4	1.1	1.7	-0.0	1.2	1.9	2.2	0.7	0.4	0.6
Lupus	0.6	0.8	3.1	-1.2	-0.1	-0.2	-1.2	0.3	1.4	0.1	0.4	1.8	1.3	0.6	0.1	0.5	1.1	1.2	-0.4	1.2	-0.3	-0.6	0.7	0.2	-1.4	-1.3	1.0	1.0	-0.3
Ulcerative Colitis	0.6	0.9	6.4	-0.1	-0.3	-1.3	0.8	-1.1	0.3	0.6	0.5	-0.7	0.3	-0.8	-1.3	-0.8	1.3	0.0	-1.3	0.5	-2.5	2.1	-0.2	0.2	0.2	0.9	0.1	-0.3	-0.8
Blood White Count	0.6	4.7	16.6	0.4	1.9	0.3	1.3	0.6	2.4	3.7	3.3	1.1	2.4	1.2	-0.4	0.9	2.5	1.9	0.7	2.2	2.7	1.7	1.7	3.4	2.2	4.1	3.1	1.8	1.9
Medication: Atenolol	0.6	0.7	6.6	2.6	0.9	1.3	1.3	0.2	0.4	0.6	0.4	0.0	0.3	0.4	1.1	1.2	0.5	0.5	0.8	0.6	-0.0	0.7	0.2	0.1	0.8	0.5	0.4	0.4	0.2
Alcohol usually taken with meals	0.6	1.0	3.4	-1.8	-0.1	-0.5	-1.1	-1.7	-1.2	-0.8	-1.1	-1.1	-1.2	-1.2	-1.1	-1.1	-1.1	-1.3	-0.5	-1.4	-0.7	-0.3	-0.4	-0.5	-0.4	-0.5	-0.7	-1.3	-0.5
Mouth/teeth dental problems: Bleeding gums	0.6	0.8	2.2	-0.3	-0.8	-0.3	-1.3	-0.8	-0.8	-0.2	-0.4	-1.0	-0.8	-1.5	-0.9	-0.3	-0.7	-1.1	-0.2	-0.8	-0.5	0.1	-1.3	-0.9	-0.8	-1.3	-0.8	-1.2	-1.5
High blood pressure (siblings)	0.6	0.9	2.3	1.3	1.1	1.5	1.0	1.2	0.9	0.8	0.8	0.5	0.8	1.2	-0.1	0.5	0.9	1.0	0.3	0.8	0.2	1.1	0.7	0.7	0.7	1.4	0.7	1.1	1.0
Number of children fathered	0.6	0.7	2.7	-0.2	-0.7	-0.4	-1.1	-1.6	-0.7	-0.7	-0.8	-1.1	-0.8	-0.8	-0.8	-0.8	-0.8	-0.8	-1.0	-0.9	-1.2	0.2	-0.9	-0.9	0.1	-0.9	-0.5	-0.9	-0.6
Qualifications: College or University degree	0.6	1.9	5.7	-0.2	0.1	-0.3	-0.3	-0.8	-2.4	-0.7	-1.3	-1.9	-2.3	-2.0	-0.2	-0.5	-2.1	-2.3	-0.0	-2.2	-0.0	-0.6	-1.2	-1.2	0.1	-0.9	-1.5	-2.3	-0.7
Medication for pain relief, constipation, heartburn	0.6	1.0	4.0	-1.2	-0.9	-0.4	-0.6	-0.9	-0.5	0.0	-0.2	-1.4	-0.6	-1.5	-1.4	-0.4	-0.6	-1.0	-0.4	-0.7	-0.1	1.4	-1.4	-1.0	-2.0	-0.4	-1.0	-1.1	-1.6
Alcohol intake frequency.	0.6	1.4	12.4	2.1	0.9	0.7	1.4	2.5	0.6	0.7	0.7	-0.2	0.6	-0.1	-0.1	0.7	0.9	0.4	1.2	0.7	0.4	1.9	0.5	-0.1	3.5	0.8	0.3	0.3	-0.5
Number of full sisters	0.6	0.8	2.4	0.8	-0.7	0.1	-1.3	-0.5	-1.2	-1.0	-1.1	-1.5	-1.2	-0.9	-0.2	0.1	-1.2	-1.1	-0.4	-1.1	0.1	0.2	-0.9	-0.9	-0.5	-0.7	-1.1	-1.0	-0.6
Overall health rating	0.6	1.4	6.3	2.5	0.8	0.8	1.3	1.7	1.2	0.6	0.9	1.1	1.2	1.5	1.6	0.5	1.4	1.5	0.8	1.4	0.1	0.3	1.1	0.5	1.1	0.6	0.9	1.4	0.8
Knee pain experienced in last month	0.6	1.0	6.5	-0.2	-0.6	-0.7	-1.4	0.8	-0.3	-1.0	-0.8	-0.6	-0.3	-0.7	-1.1	-2.4	-0.3	-0.4	-1.3	-0.4	-2.6	0.1	-0.3	-0.9	-0.5	-1.4	-0.5	-0.5	-1.1
Mood swings	0.6	1.2	9.3	2.9	0.9	0.9	0.8	1.5	-0.4	-1.5	-1.0	-0.3	-0.4	0.7	0.6	-1.0	-0.6	0.2	0.1	-0.4	-0.8	-0.5	0.6	-0.5	3.0	0.5	-0.1	0.1	0.7
Loneliness, isolation	0.6	0.8	3.3	-0.5	1.2	1.1	0.4	0.8	0.1	-0.7	-0.4	1.2	0.2	1.4	1.2	-0.0	-0.2	0.6	0.9	-0.0	0.9	-1.8	1.3	0.4	0.7	0.3	0.4	0.8	1.5
Depressed Affect (Nagel 2018)	0.5	1.0	5.2	2.0	-0.3	-0.1	-0.0	0.6	-0.9	-1.8	-1.5	-0.4	-0.9	0.1	0.2	-1.2	-1.0	-0.4	-0.3	-0.8	-1.0	-1.5	-0.1	-0.9	2.3	-0.7	-0.7	-0.4	0.2
Schizophrenia vs Biploar Disorder	0.5	0.7	3.8	-1.5	-0.2	0.6	-0.1	1.1	1.2	0.6	1.0	0.9	1.2	-0.2	0.7	0.4	1.0	0.6	0.6	0.8	1.9	0.4	-0.0	0.6	-0.2	-0.1	0.9	0.5	-0.5
Blood Platelet Count	0.5	5.7	10.8	0.3	2.3	1.4	2.6	0.8	2.5	2.3	2.3	2.5	2.5	3.1	3.2	0.5	2.2	2.9	2.0	2.2	1.6	-0.3	2.6	3.1	2.1	3.3	3.1	2.9	3.2
Frequency of depressed mood in last 2 weeks	0.5	0.7	3.1	0.9	0.4	0.8	0.8	0.7	-1.1	-1.5	-1.3	-0.2	-1.1	0.1	0.5	-0.2	-1.0	-0.6	0.3	-1.0	-0.9	-0.7	0.2	-1.0	1.8	-0.7	-1.0	-0.5	0.2
Eye problems/disorders: Diabetes related eye disease	0.5	0.5	3.4	0.5	0.4	0.5	0.1	0.8	0.4	1.2	1.1	-0.1	0.5	0.1	-0.8	1.4	0.4	0.3	0.6	0.5	1.8	0.6	-0.1	0.7	-0.1	1.2	0.4	0.3	0.3
Vitamin and mineral supplements	0.5	0.7	1.6	0.9	0.1	0.2	-0.1	0.1	1.2	0.9	1.0	1.2	1.2	1.1	1.1	-0.1	1.1	1.2	-1.1	1.1	0.3	0.4	0.6	0.4	-0.9	-0.1	0.7	1.2	0.3
Diabetes (father)	0.5	0.6	3.6	-0.5	-0.0	0.2	-1.5	-0.8	-1.2	-0.2	-0.6	-0.4	-1.1	-0.9	0.6	0.2	-1.0	-1.0	-0.0	-1.0	0.9	-1.9	-0.5	-0.2	-0.4	-0.8	-0.1	-1.0	0.2
Average weekly fortified wine intake	0.5	0.6	5.6	-1.5	0.6	-0.1	-0.4	-1.0	-0.5	-0.4	-0.4	0.3	-0.4	0.3	-0.4	-0.2	-0.4	-0.2	0.0	-0.3	1.1	-2.4	0.7	0.8	-0.1	0.5	0.2	-0.0	1.2
Relative age voice broke	0.5	0.7	5.1	-1.7	0.1	-0.4	-0.4	-2.2	-0.2	-0.3	-0.4	0.8	-0.2	0.6	0.6	0.1	-0.5	0.1	-1.4	-0.3	0.7	-1.4	0.4	0.4	-1.7	-0.5	-0.0	0.2	0.9
High blood pressure	0.5	1.5	10.6	3.2	1.1	1.2	1.8	2.0	1.1	0.8	0.9	0.2	1.0	1.1	1.1	0.6	0.9	1.2	0.6	1.1	0.2	1.6	0.6	0.3	1.2	1.2	0.8	1.1	0.5
Stomach or abdominal pain in last month	0.5	0.6	2.0	-0.9	-0.6	-1.4	-1.4	-0.9	-0.3	-1.0	-0.6	0.3	-0.2	0.0	0.1	-1.4	-0.3	-0.2	-1.4	-0.3	-0.1	-1.2	0.2	-0.1	-1.4	-0.8	-0.3	-0.1	0.1
High blood pressure (mother)	0.5	0.6	3.8	0.4	-0.7	-0.0	0.6	2.0	0.2	0.1	0.2	-0.2	0.2	-0.9	-0.3	1.8	0.2	-0.2	1.4	0.4	0.1	1.1	-1.0	-0.6	0.3	-0.6	-0.3	-0.4	-1.4
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.8	3.5	0.9	1.1	1.2	1.0	0.9	-0.8	-1.0	-0.9	0.3	-0.8	1.3	0.6	-0.3	-0.8	0.1	0.7	-0.8	0.2	-1.0	1.0	0.1	1.8	0.4	-0.2	0.3	1.9
Hearing difficulty/problems with background noise	0.5	0.9	3.2	-0.6	-0.1	-0.9	-0.5	-0.8	-1.2	-1.2	-1.2	-0.9	-1.2	-0.5	-1.8	-1.2	-1.1	-1.0	-1.3	-1.0	-0.8	-1.3	-0.0	-0.5	0.4	0.0	-0.7	-0.9	0.2
Heart attack	0.5	0.6	2.6	0.3	0.6	0.8	0.8	0.5	0.1	-0.9	-0.5	0.8	0.1	1.3	1.6	-0.5	-0.4	0.6	-0.1	-0.2	1.1	-0.8	1.1	0.2	0.7	0.2	0.2	0.8	1.4
Fluid intelligence score	0.5	1.0	5.1	-1.4	-0.7	-1.3	-1.7	-2.3	-0.6	-0.3	-0.4	-0.6	-0.6	-0.8	-1.0	-1.5	-0.8	-0.7	-1.8	-0.9	-0.4	-0.5	-0.8	0.1	-1.2	-0.2	-0.2	-0.7	-0.2
Neuroticism score	0.5	1.0	3.8	1.4	0.2	0.5	-0.3	0.0	-1.1	-1.9	-1.5	-0.2	-1.0	0.7	0.4	-1.6	-1.4	-0.3	-0.9	-1.1	-1.1	-1.6	0.2	-0.8	1.3	-0.4	-0.7	-0.2	1.0
Time employed in main current job	0.5	0.6	2.9	-0.0	-0.7	-0.5	0.2	0.8	1.1	0.4	0.8	1.0	1.1	0.2	0.8	0.9	0.8	0.8	1.7	1.2	-1.0	-0.1	-0.2	0.1	-0.3	-0.5	0.6	0.6	-0.6
Father’s age at death	0.5	0.7	2.6	-1.5	-0.0	-0.9	-1.3	-0.3	-0.7	-0.7	-0.7	-0.7	-0.7	-0.9	-1.1	-1.6	-0.8	-0.8	0.0	-0.7	-1.0	-0.6	0.2	-0.3	0.7	-0.5	-0.4	-0.8	-0.5
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.6	1.6	-0.7	-0.6	0.4	-0.8	-0.1	-0.9	-0.5	-0.7	-1.0	-0.8	-1.2	-0.3	0.5	-1.0	-1.1	0.1	-0.8	0.3	0.1	-1.2	-0.8	-0.7	-0.7	-0.9	-1.1	-1.1
Mouth/teeth dental problems: Dentures	0.5	0.9	3.2	1.4	-0.3	-0.1	1.8	1.0	1.0	1.5	1.3	0.4	1.0	0.3	1.3	1.3	1.3	0.9	0.8	1.4	-0.0	0.9	-0.3	0.4	0.3	0.7	0.7	0.7	-0.3
Medication: Lansoprazole	0.5	0.6	1.5	1.2	-0.1	-0.1	0.0	-1.0	0.9	0.4	0.7	0.8	1.0	1.1	1.1	0.8	0.8	1.0	0.6	1.1	0.1	0.8	0.2	0.5	0.3	0.5	0.6	1.0	0.5
Health satisfaction	0.5	0.7	6.9	2.6	0.2	0.7	0.4	-0.9	-0.8	-0.3	-0.4	-0.2	-0.7	0.7	1.0	1.0	-0.7	-0.1	0.0	-0.2	0.6	-1.4	-0.3	-0.3	0.7	0.4	-0.2	0.0	1.2
Medication: Ibuprofen	0.5	0.6	2.7	1.6	-0.1	0.0	0.2	1.0	-1.0	-1.1	-1.0	-0.7	-1.0	-0.2	0.4	-0.7	-0.8	-0.7	0.1	-1.0	-1.2	-0.1	-0.0	-0.8	1.1	-0.5	-0.8	-0.6	-0.1
Chest pain or discomfort	0.5	0.8	7.5	1.9	0.6	0.4	1.4	1.6	0.1	0.0	0.1	-0.1	0.1	0.4	0.6	-0.9	0.5	0.3	0.3	0.1	-0.7	0.9	0.8	0.1	2.7	0.5	0.2	0.2	0.3
Long-standing illness, disability or infirmity	0.5	0.8	4.8	0.3	0.6	0.7	-0.0	2.0	0.5	1.1	0.9	-0.1	0.6	-0.4	0.0	0.8	0.7	0.2	2.0	0.7	0.6	-0.2	0.1	0.8	2.2	0.7	1.3	0.1	0.2
Ever had bowel cancer screening	0.5	0.5	2.4	-0.6	-1.5	-1.2	-1.4	-1.0	0.2	0.1	0.1	-0.1	0.2	-0.6	0.0	-0.6	0.3	-0.1	-1.0	0.2	-1.0	0.2	-0.8	-0.3	-0.9	-0.9	0.1	-0.2	-1.0
Commuting to job workplace: Walk	0.5	0.5	2.2	0.6	-0.7	0.8	-0.8	0.8	0.0	-0.1	-0.1	-0.3	0.0	-1.0	-0.7	0.3	-0.1	-0.4	0.2	-0.2	0.8	0.3	-1.1	-0.7	-1.3	-1.1	-0.6	-0.5	-1.5
Medication for cholesterol	0.5	0.8	8.3	-2.1	-0.8	-1.1	-1.5	-0.7	-0.4	0.2	-0.1	0.4	-0.4	-0.5	-0.6	-0.5	-0.6	-0.5	-0.3	-0.4	0.4	-2.9	-0.1	0.4	-0.4	-0.6	0.2	-0.4	0.2
Mineral and other dietary supplements	0.5	0.7	1.8	1.0	-0.8	-0.9	0.3	0.1	1.2	0.8	0.9	1.0	1.1	0.5	-0.1	-0.6	1.3	1.0	-1.4	1.2	-0.8	0.4	-0.1	-0.0	-0.9	-0.5	0.5	0.8	-0.5
Diastolic blood pressure, automated reading	0.5	1.7	14.2	2.4	0.4	0.8	2.7	2.4	0.7	0.6	0.6	-0.5	0.5	0.6	0.5	-0.2	0.9	0.7	-0.2	0.5	-1.8	3.8	-0.0	-0.8	0.4	0.8	-0.2	0.6	-0.5
Vascular/heart problems diagnosed by doctor	0.5	1.4	10.9	-3.3	-1.0	-0.7	-2.0	-1.9	-0.8	-0.4	-0.5	0.1	-0.7	-1.1	-0.7	-0.4	-0.7	-1.0	-0.3	-0.9	-0.1	-1.9	-0.7	-0.2	-1.5	-1.4	-0.6	-1.0	-0.7
Supplements: Calcium	0.5	0.5	1.5	0.3	-0.6	-0.6	-0.6	-0.1	-0.8	-0.3	-0.5	-1.1	-0.9	-1.0	-1.0	-1.2	-0.9	-0.9	-0.2	-0.9	-0.8	0.2	-0.9	-0.6	0.6	-0.5	-0.4	-1.0	-0.7
Deep venous thrombosis (DVT) (self-reported)	0.5	0.7	4.0	0.4	0.3	0.2	0.7	-0.4	-0.7	-0.5	-0.6	-1.2	-0.8	-0.8	-0.8	-0.7	-0.4	-0.9	-0.4	-1.1	-1.3	2.0	-0.2	-0.7	1.2	-0.0	-1.0	-0.9	-0.7
Verbal and Numeric Reasoning (VNR)	0.4	0.9	5.5	-2.0	0.2	-0.3	-1.1	-2.3	-0.4	0.1	-0.0	0.5	-0.3	0.4	0.5	-0.1	-0.7	-0.1	-0.8	-0.8	1.5	-2.2	0.3	1.1	-0.2	0.6	0.6	0.0	1.6
Bipolar Disorder (2011)	0.4	0.4	4.3	2.1	-0.2	0.2	1.3	0.2	-0.2	0.5	0.1	-0.4	-0.3	-0.1	0.2	0.3	-0.1	-0.2	0.2	-0.1	-0.2	0.9	-0.7	-0.5	0.8	0.2	-0.5	-0.2	-0.4
Body Mass Index (BMI) (2010)	0.4	0.6	1.6	-0.6	0.2	-0.5	0.1	0.4	1.1	1.0	1.0	1.2	1.1	0.8	-0.1	0.1	1.2	1.0	0.0	1.2	-0.1	0.3	0.8	0.8	-0.3	0.4	0.9	1.0	0.4
Type 2 Diabetes (T2D) (2012)	0.4	0.4	2.0	0.1	0.0	-0.2	1.0	-0.7	-0.9	-0.3	-0.3	-1.1	-0.9	-0.6	-0.0	-0.4	-0.7	-0.7	-0.6	-0.8	-0.5	1.4	-0.6	-0.4	-0.1	0.3	-0.7	-0.9	-0.1
BMI	0.4	2.3	5.7	1.3	1.5	1.5	1.6	0.8	1.7	2.3	2.0	0.5	1.6	1.1	0.8	0.5	1.8	1.5	0.8	1.4	0.9	1.8	1.0	1.7	1.9	2.4	2.0	1.4	1.1
Smoking Status	0.4	0.9	2.2	0.6	-1.5	-1.4	0.4	-0.4	-0.8	-0.7	-0.9	-1.1	-0.9	-1.0	-0.8	0.2	-0.6	-0.9	0.4	-0.4	-1.5	-0.9	-1.3	-1.1	-0.3	-0.9	-1.1	-1.0	-1.0
Supplements: Zinc	0.4	0.4	1.8	-0.8	-0.2	0.5	-1.0	-0.2	0.7	0.0	0.3	0.7	0.7	0.4	0.3	0.0	0.4	0.6	1.3	0.6	1.0	-1.3	0.2	0.8	0.3	0.5	0.8	0.6	0.4
Leg fat-free mass (left)	0.4	2.0	5.3	0.2	1.8	2.2	1.4	1.1	1.5	1.9	1.7	0.7	1.4	0.8	1.4	0.8	1.6	1.2	1.2	1.2	0.7	1.3	1.3	1.3	2.3	1.7	1.8	1.2	0.8
Hand grip strength (right)	0.4	1.1	4.3	-0.9	-1.4	-0.8	-0.1	1.2	-0.6	-1.2	-1.0	-0.9	-0.7	-1.0	-0.2	-0.8	-0.7	-0.9	-0.5	-0.7	-2.1	0.4	-0.8	-1.5	-1.2	-1.5	-1.3	-0.9	-1.6
Fed-up feelings	0.4	0.7	3.0	1.3	0.4	-0.0	0.4	-0.4	-0.8	-1.5	-1.3	0.4	-0.8	1.0	0.2	0.1	-0.7	-0.0	-0.4	-0.6	-0.3	-1.6	0.6	-0.5	1.7	-0.2	-0.6	0.1	1.1
Bilateral oophorectomy (both ovaries removed)	0.4	0.5	2.7	-0.5	1.2	1.6	0.7	0.0	0.2	0.0	0.1	0.7	0.1	1.0	1.1	0.3	0.2	0.4	0.6	-0.1	1.1	0.2	1.0	0.6	-0.5	0.2	0.6	0.6	1.3
Supplements: Glucosamine	0.4	0.5	2.9	0.3	1.4	1.0	0.4	-0.3	-0.4	-0.1	-0.1	-0.5	-0.4	0.2	0.7	-0.5	-0.5	-0.1	0.6	-0.7	0.7	0.3	0.6	0.8	1.7	1.4	0.5	-0.1	1.1
Impedance of leg (left)	0.4	2.0	9.5	-1.0	-1.3	-1.5	-1.8	-1.3	-1.3	-2.1	-1.8	0.2	-1.2	-0.1	-0.6	-0.3	-1.5	-0.8	-1.2	-1.0	-0.6	-2.8	-0.7	-0.9	-3.1	-2.3	-1.4	-0.7	-0.2
Leg predicted mass (left)	0.4	1.9	4.8	0.2	1.7	2.1	1.4	1.0	1.5	1.9	1.7	0.7	1.4	0.8	1.4	0.8	1.6	1.2	1.1	1.2	0.7	1.2	1.2	1.3	2.2	1.7	1.8	1.2	0.8
Past tobacco smoking	0.4	0.8	2.3	-0.8	0.7	0.1	-0.5	1.0	1.0	1.0	1.1	1.3	1.1	0.8	0.4	0.2	0.9	1.0	-0.4	0.9	1.5	-0.1	1.1	1.2	-0.1	0.2	1.2	1.0	0.8
Nervous feelings	0.4	0.8	2.2	1.3	0.6	0.5	0.3	-1.3	-0.7	-1.4	-1.2	-0.2	-0.7	1.0	1.0	-1.1	-0.8	0.1	-1.5	-0.7	0.0	-0.7	0.6	-0.1	1.4	0.3	-0.2	0.2	1.3
Heel bone mineral density (BMD) T-score, automated (right)	0.4	0.9	3.2	-1.8	1.1	1.3	-1.4	-0.3	0.9	1.1	1.2	1.1	1.1	0.5	0.3	0.3	0.8	0.7	0.4	0.6	1.1	0.1	1.1	1.2	-0.1	0.3	1.2	0.8	0.6
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	5.0	1.8	0.6	1.3	0.5	0.8	-0.3	-0.2	-0.1	-0.5	-0.3	0.3	1.1	0.1	-0.4	-0.0	0.7	-0.3	0.2	0.4	0.1	-0.4	2.2	0.3	-0.0	-0.0	0.3
Falls in the last year	0.4	0.5	1.8	0.0	-0.3	-0.6	0.1	-0.7	0.8	0.7	0.9	0.7	0.9	0.6	-0.1	0.2	0.8	0.8	1.4	0.9	0.4	-0.2	0.3	0.9	0.1	1.1	0.9	0.8	0.5
Forced expiratory volume in 1-second (FEV1)	0.4	1.2	4.8	-1.6	-0.8	0.3	-2.2	-0.8	-1.0	-1.3	-1.2	-0.1	-0.9	-0.9	0.5	-0.3	-1.3	-1.0	-0.9	-1.1	-0.0	-1.9	-0.6	-0.8	-1.5	-1.9	-0.8	-0.9	-0.6
Breastfed as a baby	0.4	0.5	2.5	-1.2	-0.4	-0.4	-0.1	-0.4	0.8	0.9	0.9	1.0	0.8	-0.1	-0.5	0.8	0.6	0.5	0.8	1.1	0.5	-0.9	-0.3	0.1	-1.6	-0.7	0.5	0.3	-0.6
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.5	2.2	1.3	0.5	1.5	-0.0	0.7	-0.6	-1.0	-0.9	-0.0	-0.6	0.4	1.1	-0.9	-1.0	-0.1	0.1	-0.7	0.5	-1.0	0.1	-0.4	0.8	-0.9	-0.2	-0.0	0.4
Ever highly irritable/argumentative for 2 days	0.4	0.5	1.8	0.1	-0.0	-0.3	-0.3	-0.6	-1.0	-1.4	-1.2	-0.2	-0.9	0.1	0.2	-0.8	-1.3	-0.5	-0.5	-1.1	0.3	-0.7	-0.0	-0.6	-0.2	-0.7	-0.8	-0.4	0.3
Blood clot in the leg (DVT)	0.4	0.5	3.7	0.5	0.6	0.5	0.8	-0.2	-0.4	-0.3	-0.3	-0.8	-0.5	-0.4	-0.2	-0.7	-0.2	-0.5	-0.1	-0.8	-0.9	1.9	0.2	-0.3	1.6	0.2	-0.5	-0.5	-0.3
Forced vital capacity (FVC), Best measure	0.4	1.6	5.8	-1.2	-1.3	-0.1	-2.4	-0.7	-1.3	-2.0	-1.8	-0.8	-1.2	-1.2	0.5	-0.8	-1.7	-1.3	-0.8	-1.4	0.1	-1.7	-1.0	-0.9	-1.1	-1.5	-1.0	-1.2	-0.8
Exposure to tobacco smoke outside home	0.4	0.6	3.4	1.9	0.3	-0.1	1.1	1.4	0.7	0.5	0.6	0.3	0.6	0.5	-0.5	0.3	1.0	0.7	1.0	0.8	0.2	0.4	0.3	0.5	0.7	1.1	0.5	0.6	0.2
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.5	1.8	-1.1	-0.1	0.5	0.5	0.2	1.0	1.2	1.0	0.6	0.9	-0.1	0.4	0.7	1.0	0.5	0.0	0.9	0.1	0.9	-0.3	0.2	-1.3	-0.1	0.6	0.4	-0.5
Angina (self-reported)	0.4	0.5	3.6	1.5	0.7	0.4	1.3	0.5	-0.5	0.1	-0.2	-0.2	-0.6	0.4	0.5	0.6	-0.2	-0.2	0.5	-0.3	0.1	-0.1	0.5	0.3	1.9	0.7	-0.1	-0.1	0.9
Migraine (self-reported)	0.4	0.6	2.2	0.3	1.1	1.3	0.8	1.5	0.4	0.7	0.5	0.2	0.4	0.4	0.9	-1.0	0.5	0.5	1.2	0.5	-0.8	0.4	0.7	0.4	0.7	0.2	0.8	0.4	0.4
Medication: Omeprazole	0.4	0.5	1.4	1.2	-0.5	-0.8	0.0	-0.8	-1.1	-0.5	-0.8	-0.6	-1.1	-0.3	0.2	-0.1	-0.9	-0.7	0.3	-0.6	-1.2	-1.2	-0.6	-0.5	-0.0	-0.2	-0.7	-0.7	0.2
Medication: Seretide 50 evohaler	0.4	0.5	1.8	0.1	-0.3	-1.3	-0.9	-0.7	0.6	0.6	0.8	0.5	0.8	0.1	-0.4	0.0	0.6	0.5	0.0	0.6	1.0	-0.5	0.4	1.0	0.5	1.2	0.9	0.4	0.5
Commuting to job workplace: Car/motor vehicle	0.4	0.5	3.7	-0.3	0.3	-0.6	-0.6	-0.2	-0.2	-0.4	-0.4	-0.1	-0.3	-0.4	-0.6	-1.1	0.1	-0.3	-0.8	-0.4	-1.9	0.6	0.7	-0.3	1.5	-1.1	-0.0	-0.4	-0.3
Illnesses of siblings: Diabetes	0.4	0.5	1.4	0.3	-0.2	0.4	-0.4	-0.7	-1.2	-0.5	-0.7	-1.0	-1.1	-0.8	-0.8	0.2	-1.0	-1.1	-0.0	-1.1	0.0	-0.5	-0.7	-0.4	0.7	-0.1	-0.5	-1.0	0.2
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.5	3.3	0.4	0.9	0.5	1.8	1.1	0.5	0.7	0.6	-0.1	0.3	0.4	0.3	0.5	0.6	0.5	0.4	0.5	-0.6	1.4	0.5	0.3	0.4	0.8	0.5	0.4	0.3
Asthma (self-reported)	0.4	0.7	1.9	-0.1	1.0	0.2	0.5	-0.5	0.9	0.5	0.6	1.3	0.8	1.2	0.5	-0.2	0.8	1.0	0.1	0.6	0.3	-0.7	1.3	1.4	1.0	0.8	1.2	1.0	1.4
Medication: Gliclazide	0.4	0.4	1.2	0.6	0.0	-0.2	-1.1	-0.0	-1.0	-0.5	-0.6	-1.1	-0.9	-0.7	-0.7	-1.1	-0.7	-0.8	-0.5	-0.7	0.4	-0.2	-0.2	-0.4	0.6	-0.1	-0.5	-0.8	-0.1
Illnesses of father: High blood pressure	0.4	0.5	2.6	1.6	-0.8	-0.3	0.2	1.1	0.6	0.9	0.8	-0.2	0.6	0.1	-0.2	0.2	0.7	0.5	0.8	1.0	-0.9	1.2	-0.6	-0.3	0.5	0.5	0.1	0.4	-0.7
Heart attack/myocardial infarction (self-reported)	0.4	0.6	2.3	0.2	0.6	0.9	0.9	0.8	0.0	-1.0	-0.6	0.8	0.0	1.3	1.5	-0.5	-0.4	0.5	-0.1	-0.2	0.9	-0.7	1.1	0.1	0.7	0.0	0.2	0.7	1.3
Crohns Disease (2017)	0.3	0.6	3.1	1.7	0.4	-0.5	1.2	0.5	0.3	0.6	0.4	-0.2	0.4	0.8	-0.3	-0.4	0.9	0.6	-0.3	0.6	-1.0	1.3	0.5	0.6	0.5	1.8	0.3	0.6	0.7
Coronary Artery Disease (CAD)	0.3	0.3	1.4	-0.4	1.0	0.7	-1.2	-0.4	0.0	0.1	-0.0	0.1	-0.1	-0.0	-0.2	-0.5	0.1	0.3	-1.0	-0.3	-0.2	-0.1	1.0	0.7	-0.5	-0.2	0.8	-0.1	0.7
LDL Cholesterol	0.3	0.5	2.2	0.9	-0.4	0.3	0.3	1.3	0.3	-0.3	-1.0	-0.8	-0.2	0.5	0.3	-1.5	-0.7	-0.2	0.8	-0.0	-0.7	1.0	-0.3	-1.2	0.6	0.3	-0.7	0.4	-0.8
Neuroticism (2016)	0.3	0.4	1.7	0.6	0.9	-0.1	0.9	0.1	-0.5	-0.9	-0.7	0.2	-0.7	0.8	0.4	-1.0	-0.7	0.3	-0.2	-0.6	-0.6	-0.6	1.2	0.1	0.6	0.0	0.1	0.1	1.3
Heel T-Score	0.3	2.2	4.2	-1.0	1.6	0.7	1.1	1.5	1.6	1.9	2.0	1.4	1.7	1.2	0.7	0.8	1.8	1.5	1.5	1.5	1.2	1.2	2.0	2.1	1.0	1.6	1.8	1.5	1.1
Systolic Blood Pressure	0.3	1.4	6.7	2.5	-0.2	0.7	2.5	2.6	-0.4	-0.8	-0.7	-0.9	-0.6	-0.1	0.8	0.6	-0.4	-0.3	-0.5	-0.4	-1.0	2.4	-0.5	-1.7	0.6	-0.6	-1.3	-0.3	-1.0
Cardiovascular Disease	0.3	1.1	11.2	3.4	-0.1	0.4	1.8	1.4	0.0	-0.0	-0.0	-1.0	-0.1	-0.0	0.0	1.0	0.1	0.1	-0.1	0.3	-0.7	2.2	-0.9	-1.0	0.7	0.5	-0.6	-0.0	-0.7
Respiratory disease	0.3	0.6	2.3	1.5	0.8	0.5	0.6	-0.0	0.5	0.4	0.4	0.4	0.4	0.8	1.3	-0.2	0.5	0.7	0.6	0.5	-0.6	-0.3	1.0	0.8	1.5	0.9	0.9	0.7	0.9
Type 2 Diabetes (T2D) (2018)	0.3	0.6	1.8	0.7	0.6	1.0	0.1	0.7	-1.3	-0.9	-0.9	-1.1	-1.2	-0.7	-0.5	-0.2	-1.0	-1.1	-0.3	-1.2	0.8	-0.4	-0.0	-0.3	1.4	-0.0	-0.6	-1.0	0.2
Sensitivity / hurt feelings	0.3	0.5	4.2	-0.3	-0.6	-1.1	-0.3	-0.5	0.2	-0.4	-0.1	0.2	0.2	0.4	-1.0	-1.5	-0.1	0.2	-2.0	-0.1	-1.3	-0.0	-0.0	-0.1	-0.7	-0.1	0.0	0.3	0.2
Hearing difficulty/problems: Yes	0.3	0.5	1.8	1.4	0.4	1.2	0.5	0.6	-0.7	0.5	0.1	-1.1	-0.7	-0.4	-1.1	-0.1	-0.5	-0.6	-0.1	-0.5	0.6	0.9	-0.5	-0.2	1.2	0.8	-0.4	-0.5	0.1
Systolic blood pressure, automated reading	0.3	0.8	6.2	1.6	0.2	0.6	1.9	0.9	0.6	0.8	0.6	-0.1	0.4	0.7	1.1	1.0	0.7	0.6	-0.1	0.5	-1.0	2.5	-0.0	-0.3	0.1	0.7	-0.0	0.6	-0.0
Angina	0.3	0.5	2.7	1.4	0.8	0.4	1.3	0.4	-0.7	-0.1	-0.4	-0.2	-0.7	0.5	0.3	0.5	-0.4	-0.3	0.4	-0.5	0.2	-0.2	0.6	0.3	1.6	0.6	-0.2	-0.1	1.1
Medication: Metformin	0.3	0.4	2.8	0.5	1.1	1.2	0.3	-0.0	-0.2	-0.0	0.1	0.0	-0.1	0.5	0.7	0.6	0.1	0.1	0.5	-0.1	0.2	-0.2	0.9	0.4	1.7	0.8	0.0	0.2	0.8
Maternal smoking around birth	0.3	0.5	1.7	0.4	-0.4	-0.2	0.6	-0.5	-0.8	-0.8	-0.9	-0.7	-0.9	-0.2	0.5	-0.1	-0.5	-0.6	0.2	-0.9	-1.3	1.1	-0.6	-1.1	0.3	-0.5	-1.2	-0.5	-0.4
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.7	7.5	-2.7	0.6	0.7	-2.0	-1.1	0.1	0.3	0.3	0.4	0.2	-0.0	-0.0	-0.3	-0.1	-0.1	-0.2	-0.3	1.0	-0.4	0.8	0.8	-0.5	-0.0	0.6	0.0	0.5
Qualifications: CSEs or equivalent	0.3	0.4	1.2	0.8	-0.8	0.0	1.1	0.4	0.7	0.3	0.5	0.6	0.6	0.1	0.5	1.1	0.7	0.5	0.1	0.8	-0.4	0.3	-0.7	-0.5	-0.4	-0.8	-0.1	0.4	-0.9
Medication: Levothyroxine sodium	0.3	0.4	1.4	0.1	0.0	-0.6	0.1	0.3	-0.9	-0.8	-0.8	-0.5	-0.9	-0.6	0.5	-0.6	-0.7	-0.8	0.1	-0.8	-1.0	-0.0	0.1	-0.7	1.2	-1.0	-0.6	-0.8	-0.4
Pain all over the body in last month	0.3	0.3	2.4	-0.6	-0.5	-0.5	-0.8	0.5	0.3	-0.3	-0.0	0.4	0.3	0.2	-0.1	-0.8	0.2	0.3	-0.2	0.3	-0.9	-1.6	0.3	0.4	0.8	-0.1	0.7	0.3	0.3
Medication: Ramipril	0.3	0.4	3.4	1.8	-0.1	0.5	0.5	0.8	-0.5	-0.9	-0.8	-0.6	-0.6	-0.0	0.4	0.5	-0.7	-0.3	0.2	-0.5	-0.7	0.5	-0.5	-0.8	0.1	-0.2	-0.7	-0.3	-0.1
Medication: Simvastatin	0.3	0.5	3.1	1.6	-0.9	-1.2	0.6	0.1	0.3	-0.5	-0.3	-0.1	0.2	0.2	-0.3	-0.4	0.3	0.3	-0.6	0.5	-1.8	0.9	-0.3	-0.7	0.7	-0.4	-0.4	0.2	-0.6
Number of live births	0.3	0.4	1.5	0.4	0.1	0.4	-0.5	0.2	-0.9	-0.7	-0.8	-0.7	-0.9	-0.3	0.4	-0.2	-0.5	-0.7	-0.4	-0.9	-1.2	-0.7	0.2	-0.7	0.6	-0.7	-0.9	-0.6	-0.0
Happiness	0.3	0.4	1.9	1.4	-0.3	-0.3	-0.2	-0.9	-0.5	-0.7	-0.6	-0.3	-0.4	-0.3	1.2	0.7	-0.5	-0.3	0.0	-0.3	0.5	-1.2	-0.4	-0.4	1.1	0.1	-0.1	-0.4	0.1
Illnesses of mother	0.3	0.3	1.4	-0.4	-0.1	0.6	-0.4	-0.0	0.5	-0.2	0.0	0.9	0.4	0.9	1.0	-0.9	0.1	0.6	0.1	0.2	0.4	-1.2	0.6	0.1	-0.7	-0.5	0.1	0.7	0.5
Hair/balding pattern: Pattern 4	0.3	0.7	2.2	0.1	-1.2	-0.9	-0.1	0.8	1.2	0.6	0.8	0.5	1.2	-0.4	-0.0	0.8	1.3	0.6	-0.3	1.3	-0.9	1.1	-0.8	-0.1	-0.9	-0.4	0.4	0.4	-1.5
Peak expiratory flow (PEF)	0.3	0.7	4.8	-2.2	-0.1	0.1	-1.2	-1.1	-0.9	-0.9	-0.9	0.0	-0.8	-0.4	0.5	0.4	-1.0	-0.8	-0.2	-1.1	1.1	-1.3	0.3	0.2	-0.6	-0.7	-0.4	-0.6	0.5
Loud music exposure frequency	0.3	0.3	1.2	-0.3	0.7	0.5	0.5	-0.0	-0.1	-0.3	-0.2	0.7	-0.0	0.3	0.9	0.9	-0.1	0.1	0.6	-0.1	1.0	-1.1	0.7	0.3	-0.2	-0.4	0.1	0.1	0.5
Headache pain in last month	0.3	0.5	1.7	0.3	0.7	1.1	0.5	1.0	-0.3	-1.0	-0.8	1.1	-0.3	0.9	0.9	0.3	-0.5	0.2	0.0	-0.4	0.7	-1.3	0.6	0.2	0.2	-0.6	-0.0	0.4	1.1
Number of full brothers	0.3	0.4	2.4	-0.3	-0.1	0.9	-0.6	-0.7	-0.4	-0.5	-0.4	0.3	-0.4	-0.5	1.2	1.2	-0.3	-0.4	0.4	-0.4	0.3	-1.6	-0.3	-0.4	-0.7	-1.0	-0.4	-0.5	-0.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	3.8	0.3	0.6	1.2	0.1	2.0	0.4	-0.1	0.1	0.5	0.4	0.4	0.5	0.1	0.2	0.5	1.6	0.5	0.4	-0.6	0.5	0.1	0.4	-0.5	0.3	0.4	0.1
Pulse wave peak to peak time	0.3	0.3	1.0	0.3	-0.7	-0.9	-0.4	-1.0	-0.6	-0.5	-0.4	-0.8	-0.5	-0.7	-0.7	0.3	-0.6	-0.6	0.2	-0.4	0.0	-0.9	-0.7	-0.5	-0.1	0.1	-0.5	-0.6	-0.4
Shortness of breath walking on level ground	0.3	0.4	1.4	-0.2	0.2	0.4	-0.9	-0.3	-0.6	-0.6	-0.5	-0.2	-0.6	-0.6	-0.5	-0.1	-0.4	-0.7	-1.0	-0.7	-1.0	0.9	-0.1	-0.8	-0.1	-1.2	-0.7	-0.6	-0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.4	1.6	-0.6	0.3	-0.4	-0.4	-0.8	-0.5	-0.6	-0.6	-0.0	-0.5	0.6	-1.0	-1.1	-0.5	-0.2	-1.3	-0.6	0.6	-0.1	0.7	-0.1	0.1	-0.3	-0.6	0.1	0.8
Leg pain on walking	0.3	0.4	1.7	0.1	0.9	1.1	0.4	0.7	0.4	-0.5	-0.1	1.2	0.4	1.3	0.5	0.2	0.1	0.7	0.3	0.3	0.4	-0.4	1.1	0.3	-0.1	-0.1	0.2	0.9	1.0
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.3	2.1	1.1	-0.5	0.4	1.3	0.6	-0.1	-0.5	-0.3	-0.5	-0.1	0.1	-0.2	-0.3	-0.2	-0.0	0.7	-0.2	0.6	0.6	-0.2	-0.5	1.4	0.6	-0.6	0.0	-0.3
Supplements: Vitamin C	0.3	0.4	1.3	-1.1	0.5	-0.1	0.1	0.2	0.3	-0.5	-0.1	0.6	0.3	0.7	-0.5	-0.6	-0.1	0.4	0.6	-0.1	0.3	-0.5	0.9	0.8	0.8	0.8	0.6	0.5	1.1
Smoking status: Previous	0.3	0.5	3.2	0.4	-0.4	-0.0	0.8	-0.9	-0.5	-0.7	-0.7	-0.8	-0.6	-0.4	0.5	-0.2	-0.5	-0.5	0.5	-0.5	-1.8	0.1	-0.6	-0.9	0.7	-0.2	-0.8	-0.6	-0.5
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.6	3.3	-1.0	-0.3	0.2	-1.2	-1.8	-0.6	-0.9	-0.8	0.1	-0.5	-0.3	-0.1	0.6	-0.8	-0.6	-0.8	-0.6	1.0	-1.3	-0.4	-0.3	-1.1	-0.7	-0.4	-0.4	-0.1
Leg fat-free mass (right)	0.3	1.5	3.9	-0.1	1.6	2.0	1.3	0.8	1.4	1.7	1.6	0.6	1.3	0.6	1.0	0.8	1.5	1.0	0.9	1.1	0.6	1.4	1.1	1.1	1.8	1.4	1.6	1.0	0.6
Average weekly red wine intake	0.3	0.4	3.4	-1.4	0.6	-0.1	-0.7	-1.8	-0.3	-0.4	-0.4	-0.2	-0.3	-0.0	0.8	-0.9	-0.4	-0.3	-0.3	-0.4	-0.8	-0.2	0.5	0.0	-0.9	0.0	0.1	-0.2	0.4
Friendships satisfaction	0.3	0.4	2.4	1.3	-0.0	0.8	0.7	-0.4	-0.3	0.3	0.2	-0.1	-0.2	-0.0	0.2	1.1	-0.3	-0.2	1.1	-0.0	1.6	-0.7	-0.8	-0.4	-0.7	0.3	-0.4	-0.1	0.0
Breast cancer (self-reported)	0.3	0.3	1.4	0.2	0.2	0.0	1.1	1.1	0.7	0.6	0.6	0.5	0.6	0.4	-0.5	0.2	0.8	0.6	0.3	0.8	0.3	1.2	0.2	0.1	0.0	0.1	0.4	0.6	-0.1
Leg predicted mass (right)	0.3	1.6	3.9	-0.1	1.6	2.0	1.3	0.8	1.4	1.8	1.6	0.6	1.3	0.6	1.0	0.9	1.5	1.0	0.9	1.1	0.6	1.4	1.1	1.2	1.8	1.5	1.6	1.0	0.6
Financial situation satisfaction	0.3	0.3	0.8	0.3	-0.4	0.1	-0.6	0.8	-0.7	-0.8	-0.8	-0.5	-0.7	-0.7	0.6	0.2	-0.6	-0.7	0.5	-0.7	-0.3	-0.4	-0.3	-0.8	0.5	-0.9	-0.6	-0.7	-0.5
Average weekly beer plus cider intake	0.3	0.5	2.3	0.5	0.4	0.5	-0.0	-0.5	-0.0	-0.7	-0.4	0.8	-0.0	1.2	0.7	0.1	-0.4	0.5	-1.5	-0.2	0.4	-1.4	0.7	0.3	0.7	-0.1	0.2	0.6	1.3
Pain experienced in last month	0.3	0.6	2.6	1.0	-0.2	0.6	0.9	-0.1	-0.2	0.9	0.4	-1.0	-0.2	-0.2	-0.0	1.6	-0.2	-0.3	0.6	-0.1	1.2	1.6	-1.1	-0.4	-0.6	1.1	-0.7	-0.2	-0.4
Bipolar Disorder or Schizophrenia	0.2	0.6	2.1	-0.4	-0.9	-0.2	-1.1	0.7	-0.7	-1.0	-1.0	-0.0	-0.7	-0.7	-0.3	-0.7	-0.8	-0.6	-0.4	-0.8	-0.2	-1.2	-0.5	-0.8	-0.6	-1.5	-0.7	-0.7	-0.6
Neuroticism (Nagel 2018)	0.2	0.5	2.0	0.9	-0.3	0.6	-0.5	0.1	-0.7	-1.4	-1.1	0.1	-0.7	0.4	0.2	-1.3	-0.8	-0.2	-1.0	-0.8	-0.6	-1.3	0.0	-0.5	0.9	-0.8	-0.6	-0.1	0.5
Schizophrenia (2018)	0.2	0.4	1.8	-1.2	-0.7	-0.4	-0.8	1.4	0.2	-0.0	0.2	0.6	0.3	-0.9	-0.3	0.6	0.2	-0.2	0.8	0.2	1.0	-0.7	-0.4	-0.2	-0.0	-1.1	0.2	-0.4	-1.0
Reaction Time	0.2	0.4	2.4	0.0	-1.2	-1.5	-0.7	0.2	-0.0	0.3	0.2	-0.2	0.1	-0.7	-0.9	0.6	0.1	-0.2	0.7	0.3	-0.1	-0.4	-0.9	-0.3	-1.0	-0.1	-0.2	-0.3	-0.9
Schizophrenia (2014)	0.2	0.4	1.3	-0.9	-1.1	-0.5	-0.4	1.0	0.0	-0.2	-0.0	0.5	0.1	-0.7	0.1	0.8	-0.0	-0.3	0.3	-0.0	1.1	-0.5	-0.6	-0.5	-0.4	-1.1	-0.3	-0.3	-1.0
Triglycerides	0.2	0.3	1.5	0.6	-0.4	-1.2	-0.4	-0.6	-0.6	-0.6	0.2	-0.2	-0.1	-0.3	-0.6	-0.6	-0.1	-0.3	-0.3	-0.2	-1.0	-0.8	0.2	0.1	-0.1	-0.2	-0.4	-0.4	0.1
Waist Hip Ratio (WHR)	0.2	0.8	7.3	-0.2	-0.3	-0.6	0.5	1.2	0.9	0.8	0.9	1.0	0.9	1.0	-1.5	0.4	0.9	1.0	-0.5	1.1	-0.4	0.4	0.1	0.3	-2.7	0.2	-0.0	1.0	0.0
Allergy or Eczema	0.2	0.6	2.6	0.7	0.9	0.1	1.3	0.3	0.9	0.5	0.8	0.3	0.9	0.8	0.0	0.2	1.0	0.9	-0.6	1.0	-0.7	0.7	0.6	0.6	-0.1	1.6	0.8	0.8	0.7
Neuroticism	0.2	0.6	2.6	0.9	-0.1	0.4	-0.9	-1.4	-0.5	-1.2	-0.8	0.0	-0.4	0.9	0.5	-1.6	-0.8	0.1	-1.3	-0.6	-0.6	-1.0	0.1	-0.5	0.3	-0.1	-0.3	0.2	0.9
Average weekly spirits intake	0.2	0.3	3.0	-0.3	0.0	0.0	0.8	-1.0	0.1	0.2	0.1	-0.2	0.0	-0.2	0.1	1.0	0.3	-0.1	0.5	0.2	-0.7	1.7	-0.4	-0.6	-0.1	0.1	-0.5	-0.1	-0.8
Impedance of leg (right)	0.2	1.1	7.3	-0.2	-0.8	-1.1	-1.2	-0.5	-1.1	-1.7	-1.5	0.2	-1.0	0.1	-0.1	-0.2	-1.3	-0.6	-0.5	-0.8	-0.3	-2.7	-0.4	-0.6	-1.8	-1.6	-1.1	-0.5	0.1
Townsend deprivation index at recruitment	0.2	0.3	1.1	1.1	-0.2	0.2	-0.3	1.0	-0.5	-0.7	-0.6	-0.1	-0.4	0.1	0.9	0.9	-0.7	-0.2	0.9	-0.3	0.8	-0.5	-0.3	-0.1	-0.9	-0.4	-0.3	-0.1	0.1
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	2.1	-0.6	0.3	-0.1	0.3	-1.2	-0.3	-0.6	-0.6	0.5	-0.3	0.2	0.1	0.6	-0.3	-0.1	0.2	-0.2	-0.2	-1.4	0.3	0.0	-0.3	-0.5	-0.1	-0.0	0.4
Multivitamins +/- minerals	0.2	0.2	1.0	-0.9	0.6	0.4	0.3	0.2	-0.6	-0.2	-0.4	-0.6	-0.6	-0.5	-0.2	0.1	-0.4	-0.6	0.8	-0.6	0.2	-0.3	0.1	0.2	1.0	0.3	-0.0	-0.5	0.1
Chronic bronchitis/emphysema (father)	0.2	0.2	1.4	0.2	-0.6	-0.9	-0.2	-0.1	-0.4	-0.9	-0.7	0.0	-0.4	0.5	-0.2	0.4	-0.6	-0.1	-1.2	-0.5	0.4	-0.5	-0.0	-0.3	0.0	-0.2	-0.4	0.1	0.5
Allergy	0.2	0.6	2.0	-1.2	-0.8	-0.1	-1.0	-0.2	-0.8	-0.3	-0.7	-0.5	-0.8	-0.7	0.0	-0.0	-0.9	-0.9	0.7	-0.7	0.4	-0.4	-0.7	-0.6	-1.4	-1.2	-0.7	-0.7	-0.6
Asthma	0.2	0.4	1.2	0.1	0.8	0.0	0.4	-0.3	0.7	0.4	0.5	1.0	0.7	0.8	0.4	-0.3	0.7	0.8	0.2	0.4	0.1	-0.5	1.1	1.1	0.9	0.6	0.9	0.8	1.0
Pulse wave Arterial Stiffness index	0.2	0.3	1.0	-0.2	0.5	0.8	0.4	1.0	0.6	0.5	0.4	0.7	0.5	0.6	0.6	-0.2	0.6	0.6	-0.3	0.4	-0.3	0.9	0.6	0.3	-0.1	-0.2	0.4	0.6	0.2
Tense / ‘highly strung’	0.2	0.3	1.6	1.3	0.5	0.6	0.1	-0.0	-0.5	-0.9	-0.7	0.1	-0.5	0.8	0.2	-0.9	-0.6	0.1	-0.5	-0.5	-0.3	-0.1	0.3	-0.4	1.0	-0.0	-0.5	0.2	0.7
Birth weight of first child	0.2	0.4	2.7	0.2	-1.1	-0.9	-1.4	-0.8	-0.3	-0.4	-0.3	-0.2	-0.2	-0.6	-0.4	-0.5	-0.5	-0.4	-0.1	-0.3	-0.1	-1.7	-0.6	-0.2	0.4	-0.8	-0.2	-0.5	-0.6
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	3.1	0.9	0.2	-0.1	0.9	1.8	0.2	0.1	0.3	-0.0	0.2	-0.1	0.5	0.1	0.3	0.1	0.8	0.3	-0.7	0.6	0.2	-0.1	1.4	-0.1	0.2	0.0	-0.2
Chronic bronchitis/emphysema (mother)	0.2	0.3	1.4	1.2	-0.0	0.8	1.2	0.3	-0.1	0.3	0.1	-0.4	-0.2	-0.1	0.9	0.4	0.1	-0.1	-0.1	-0.1	-0.7	0.8	-0.4	-0.6	0.7	-0.1	-0.4	-0.1	-0.4
Emphysema/chronic bronchitis	0.2	0.2	1.5	1.2	-0.1	-0.2	-0.5	0.1	-0.1	-0.8	-0.5	-0.5	-0.2	-0.2	-0.2	-0.7	-0.3	-0.2	-1.0	-0.3	-0.7	0.4	0.0	-0.2	0.9	-0.2	0.1	-0.2	-0.2
Mean time to correctly identify matches	0.2	0.5	1.4	0.7	-0.6	-1.0	0.3	0.7	0.8	0.7	0.8	0.6	0.8	0.4	-0.4	1.1	0.9	0.8	1.0	1.2	0.3	-0.4	-0.2	0.4	-0.1	0.6	0.5	0.6	-0.0
Pulse rate, automated reading	0.2	0.6	2.2	0.6	0.7	0.8	0.8	0.9	0.7	1.0	0.9	0.6	0.7	1.2	0.7	0.4	0.6	0.9	0.2	0.6	0.3	1.5	0.6	0.4	-0.5	0.9	0.3	1.0	0.8
Suffer from ‘nerves’	0.2	0.4	3.0	-0.1	-0.6	-0.5	-0.9	0.4	0.1	-1.1	-0.7	0.1	0.0	0.2	0.1	-1.7	-0.2	0.2	-1.1	-0.1	-0.9	-0.3	-0.0	-0.3	0.2	-0.8	0.1	0.1	-0.1
Basal metabolic rate	0.2	1.2	3.5	-0.3	1.3	1.7	1.0	0.7	1.3	1.4	1.3	0.7	1.2	0.6	1.3	0.9	1.2	0.9	1.0	0.9	0.6	0.7	1.0	1.1	1.9	1.1	1.6	0.9	0.6
Arm fat-free mass (left)	0.2	1.3	2.7	-0.8	1.1	1.5	0.9	0.7	1.3	1.2	1.2	1.0	1.2	0.7	1.6	1.4	1.2	1.0	1.2	1.0	0.8	0.1	1.1	1.1	1.6	0.8	1.6	1.0	0.7
Fractured/broken bones in last 5 years	0.2	0.2	1.0	1.0	0.9	0.9	0.2	0.4	-0.1	0.2	0.1	-0.3	-0.1	0.3	0.5	0.5	0.2	0.1	0.0	0.1	0.6	-0.1	0.2	0.3	0.6	0.6	0.3	0.1	0.7
Age started oral contraceptive pill	0.2	0.3	1.1	0.5	-0.6	-0.8	0.5	-0.6	-0.6	-0.3	-0.4	-0.6	-0.6	-0.2	-0.2	-0.1	-0.7	-0.5	-1.1	-0.5	-0.6	-0.1	-0.5	-0.3	-0.5	0.0	-0.6	-0.5	0.0
Commuting to job workplace: Cycle	0.2	0.3	1.6	-0.0	0.2	0.2	0.6	-0.3	0.2	0.9	0.7	0.3	0.2	0.7	-0.3	0.2	0.4	0.5	-0.4	0.5	-0.2	-1.3	0.2	0.7	0.0	0.7	0.3	0.5	0.8
Medication: Omeprazole (e.g. Zanprol)	0.2	0.2	1.9	1.4	-0.2	-0.5	0.4	-0.5	-0.4	0.4	0.1	-0.2	-0.3	0.3	0.6	0.2	-0.1	-0.0	0.4	0.1	-0.2	-0.4	-0.2	0.2	0.5	0.6	0.1	-0.0	0.6
Impedance of whole body	0.2	0.8	6.8	-0.1	-0.4	-0.4	-1.2	-0.8	-0.7	-1.1	-0.9	0.3	-0.6	0.1	-0.5	0.1	-0.9	-0.3	-0.7	-0.4	-0.1	-2.0	-0.3	-0.4	-2.6	-1.4	-0.9	-0.2	-0.0
Arm predicted mass (left)	0.2	1.0	2.4	-0.6	0.9	1.4	0.7	0.6	1.1	1.0	1.1	0.8	1.1	0.6	1.5	1.1	1.0	0.8	1.0	0.9	0.7	-0.0	0.9	0.9	1.5	0.6	1.5	0.8	0.6
Primary Biliary Cirrhosis	0.1	0.1	0.7	-0.3	0.0	0.6	-0.5	0.6	-0.0	-0.2	-0.1	0.1	-0.0	0.1	-0.3	-0.1	-0.1	0.0	0.6	0.0	0.7	-0.8	0.1	0.1	0.1	0.1	0.1	0.1	0.3
Height	0.1	1.4	7.1	-0.9	0.5	2.2	-0.1	0.4	0.8	0.7	0.7	1.3	0.8	0.6	2.7	2.5	0.6	0.6	1.7	0.6	0.8	-2.2	0.8	0.8	0.3	-0.6	1.0	0.7	0.6
Hypothyroidism (self reported)	0.1	0.3	1.4	0.9	0.3	-0.0	0.1	1.0	0.5	0.2	0.4	0.4	0.6	0.4	0.9	0.2	0.6	0.6	0.4	0.7	-0.1	0.1	0.4	0.2	1.2	0.1	0.6	0.5	0.1
Lung FEV1/FVC ratio	0.1	0.7	2.8	-1.1	0.4	0.2	0.0	-0.2	1.1	1.7	1.4	0.8	1.1	0.3	-0.2	0.3	1.3	0.8	-0.8	1.1	-0.9	0.1	0.5	0.7	-0.9	-0.0	0.8	0.7	-0.2
Hair Pigment	0.1	2.3	6.2	-0.0	0.8	0.3	1.2	0.7	2.5	1.4	1.9	2.4	2.5	1.8	0.6	1.2	2.4	2.3	0.8	2.4	0.7	-0.0	1.4	1.2	-0.2	0.8	1.5	2.2	0.5
Tanning	0.1	0.9	7.0	-0.4	-0.8	-1.2	-0.0	-0.6	-0.3	-0.5	-0.3	-0.7	-0.3	-0.7	-1.1	-1.8	-0.4	-0.5	-0.6	-0.4	-2.6	1.5	-0.8	-1.1	-0.8	-0.6	-0.8	-0.6	-1.2
Age when periods started (menarche)	0.1	0.3	1.5	-1.2	-0.9	-0.9	-0.3	-0.5	-0.0	-0.2	-0.2	-0.6	-0.1	-0.6	-0.4	0.0	-0.4	-0.3	0.2	-0.3	-1.0	0.7	-0.6	-0.4	-0.1	-0.4	-0.3	-0.4	-0.8
Hayfever, allergic rhinitis or eczema	0.1	0.1	1.3	0.2	0.1	-0.5	0.1	-0.4	-0.1	-0.5	-0.1	0.1	-0.0	0.1	-0.5	-0.0	0.0	-0.0	-1.2	0.1	-0.7	-0.7	-0.1	-0.1	-0.2	0.1	-0.1	-0.1	0.1
Sitting height	0.1	0.4	3.4	-1.3	0.5	1.9	-0.5	0.4	0.3	0.5	0.5	0.2	0.3	-0.2	0.8	1.1	0.1	0.0	1.3	0.2	-0.0	-0.1	0.1	0.0	-0.8	-0.6	0.4	0.1	-0.4
Number of incorrect matches in round	0.1	0.2	2.1	0.8	0.2	-0.5	0.3	1.3	-0.3	0.1	-0.0	-0.2	-0.3	0.1	-1.4	-0.5	0.1	-0.1	-0.4	-0.1	-0.6	-0.1	0.3	-0.2	0.6	-0.1	-0.1	-0.1	0.2
Hayfever/allergic rhinitis (self-reported)	0.1	0.2	0.8	-0.9	0.5	-0.0	0.9	0.3	0.2	0.1	0.2	0.6	0.2	0.6	0.3	-0.3	0.1	0.3	-0.1	0.1	-0.1	0.0	0.4	0.4	0.4	0.6	0.5	0.4	0.7
Impedance of arm (right)	0.1	0.4	1.9	1.4	0.9	1.2	0.4	0.1	0.2	0.5	0.4	0.5	0.2	0.7	0.5	1.4	0.2	0.5	0.7	0.5	0.8	-0.8	0.2	0.3	-0.9	0.2	0.0	0.5	0.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.4	1.9	-1.2	-0.5	0.5	-1.4	-0.1	-0.3	-0.7	-0.5	-0.1	-0.2	-0.6	0.6	-0.3	-0.5	-0.4	-0.6	-0.4	0.1	-0.8	-0.5	-0.3	-1.1	-0.9	-0.2	-0.4	-0.5
Impedance of arm (left)	0.1	0.2	2.8	0.3	0.4	0.4	-0.6	-0.5	-0.3	-0.1	-0.2	0.2	-0.2	0.1	-0.4	0.5	-0.3	-0.1	-0.4	-0.0	0.3	-0.9	-0.1	-0.1	-1.7	-0.4	-0.4	-0.0	0.0
Arm fat-free mass (right)	0.1	0.5	2.0	-1.4	0.6	0.8	-0.2	-0.1	0.9	0.7	0.7	0.7	0.9	0.4	0.7	0.4	0.7	0.6	0.3	0.6	0.6	-0.2	0.8	0.9	1.1	0.5	1.3	0.6	0.5
Comparative body size at age 10	0.1	0.2	0.8	-0.3	0.5	0.3	-0.4	-0.2	-0.2	-0.8	-0.5	0.3	-0.2	0.3	-0.7	-0.8	-0.5	-0.0	-0.6	-0.4	0.6	-0.9	0.4	0.3	0.5	-0.2	0.1	0.1	0.6
Age at first live birth	0.1	0.2	0.9	0.0	0.1	0.5	-0.1	-0.3	-0.2	0.9	0.5	-0.6	-0.2	-0.7	0.4	-0.2	-0.1	-0.4	0.2	-0.2	0.1	0.6	-0.7	0.6	-0.2	0.5	0.4	-0.5	-0.1
Arm predicted mass (right)	0.1	0.4	1.8	-1.3	0.3	0.7	-0.1	-0.2	0.8	0.6	0.6	0.6	0.8	0.3	0.7	0.5	0.7	0.5	0.3	0.6	0.3	-0.1	0.6	0.7	0.9	0.4	1.1	0.5	0.3
Comparative height size at age 10	0.1	0.4	1.7	0.5	0.5	1.3	0.3	0.6	0.5	0.6	0.7	0.6	0.6	0.7	1.3	0.4	0.4	0.7	0.3	0.7	-0.2	-0.7	0.3	0.3	-0.0	-0.0	0.6	0.7	0.5
Age at last live birth	0.1	0.1	0.4	0.1	0.3	0.4	-0.1	-0.3	-0.2	0.6	0.3	-0.4	-0.2	-0.2	0.1	-0.3	0.0	-0.2	0.2	-0.2	-0.3	0.2	-0.2	0.5	-0.1	0.7	0.3	-0.2	0.3
Whole body fat-free mass	0.1	0.7	3.4	-0.5	0.9	1.2	0.6	0.4	0.9	1.1	1.0	0.4	0.8	0.2	1.0	0.8	0.9	0.5	0.7	0.6	0.5	0.5	0.7	0.8	1.9	0.9	1.3	0.5	0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.2	1.6	1.1	-0.4	0.2	-1.2	-0.3	-0.1	-0.3	-0.1	-0.2	0.0	0.0	0.8	-0.6	-0.3	0.1	-0.3	0.0	0.5	-0.5	-0.5	-0.1	-0.6	0.1	0.1	0.0	0.0
Whole body water mass	0.1	0.7	3.0	-0.7	0.9	1.3	0.6	0.4	1.0	1.2	1.0	0.4	0.9	0.1	1.0	0.9	1.0	0.5	0.7	0.7	0.5	0.4	0.7	0.8	1.7	0.8	1.3	0.5	0.3
Guilty feelings	0.1	0.2	0.7	0.4	0.4	0.8	0.2	-0.2	-0.5	-0.5	-0.5	0.1	-0.5	0.5	0.2	-0.3	-0.6	-0.1	-0.4	-0.6	0.1	-0.5	0.3	-0.1	-0.0	0.2	-0.2	0.0	0.8
Trunk fat-free mass	0.0	0.3	2.6	-0.7	0.2	0.7	0.1	0.1	0.3	0.6	0.4	-0.1	0.2	-0.5	0.8	0.6	0.3	-0.1	0.5	0.1	0.3	0.0	0.1	0.3	1.6	0.4	0.7	-0.1	-0.1
Trunk predicted mass	0.0	0.3	2.6	-0.7	0.3	0.7	0.1	0.1	0.3	0.5	0.4	-0.1	0.2	-0.5	0.8	0.7	0.3	-0.1	0.6	0.1	0.3	0.0	0.2	0.3	1.6	0.3	0.7	-0.1	-0.1
Standing height	0.0	0.4	2.5	-1.1	0.1	1.2	-1.1	-0.6	-0.0	0.1	0.0	0.3	-0.0	-0.4	0.8	1.4	-0.2	-0.3	0.5	-0.0	0.6	-1.6	-0.0	0.0	-0.1	-0.8	0.3	-0.2	-0.3

Hub : Genes

FAM21C

Models

Trait associations