Hub : Genes

FAM63B

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Artery Aorta 0.2000 0.0710 2.3e-03 0.118 NA 0.090 NA 0.116 5.0e-07 NA 1.1e-05 NA 6.1e-07
2 GTEx Artery Tibial 0.0968 0.0355 2.3e-03 0.059 NA 0.016 NA 0.023 2.0e-05 NA 1.8e-02 NA 5.8e-03
3 GTEx Cells EBV-transformed lymphocytes 0.1770 0.0780 9.3e-03 0.080 NA 0.039 NA 0.079 1.4e-03 NA 2.1e-02 NA 1.5e-03
4 GTEx Cells Transformed fibroblasts 0.1810 0.0690 9.4e-03 -0.001 NA -0.002 NA -0.001 4.2e-01 NA 5.3e-01 NA 4.3e-01
5 GTEx Esophagus Mucosa 0.0880 0.0420 8.2e-03 -0.002 NA 0.005 NA 0.009 4.7e-01 NA 1.4e-01 NA 7.7e-02
6 GTEx Heart Left Ventricle 0.2426 0.0819 6.0e-03 0.000 NA 0.088 NA 0.033 3.0e-01 NA 2.0e-05 NA 6.9e-03
7 YFS Blood 0.0411 0.0118 1.2e-09 0.038 0.032 0.044 0.035 0.044 2.2e-12 7.2e-11 4.1e-14 9.3e-12 3.6e-14
8 TCGA Cervical Squamous Cell Carcinoma 0.0970 0.0610 9.7e-03 0.010 0.038 0.062 NA 0.016 9.9e-02 5.8e-03 5.3e-04 NA 5.3e-02

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 1.6 2.5 9.1 0.8 1.2 -3.0 0.5 -2.3 0.5 -1.7 0.4
Bipolar Disorder or Schizophrenia 1.9 4.6 14.5 0.4 1.3 -3.8 0.7 -3.6 0.6 -2.5 -0.6
Depressed Affect (Nagel 2018) 0.2 0.4 1.3 0.2 0.7 -1.1 0.1 -0.7 -0.5 -0.4 0.5
Depression (Nagel 2018) 1.8 2.7 5.8 2.1 2.2 -0.9 -0.2 -1.6 -1.2 -1.1 2.4
Intelligence (Savage-Jansen 2018) 0.4 1.3 3.8 -1.2 -2.0 1.6 0.6 0.8 0.8 0.6 0.8
Neuroticism (Nagel 2018) 0.8 1.9 4.1 0.9 1.6 -1.5 0.5 -1.4 -1.6 -2.0 0.9
Schizophrenia (2018) 1.2 2.5 7.5 -0.2 0.7 -2.4 0.4 -2.7 0.5 -1.9 -1.5
Schizophrenia vs Biploar Disorder 0.4 0.5 1.7 -0.5 -0.3 1.1 -0.6 1.3 0.1 0.6 0.3
Worry (Nagel 2018) 2.0 4.2 9.5 1.8 2.5 -1.7 1.5 -2.3 -2.1 -3.1 0.8
Alzheimer’s Disease (in mother) 4.9 5.7 15.5 1.1 2.0 -3.9 1.2 -3.5 0.7 -3.2 0.4
Alzheimer’s Disease (in father) 0.8 0.9 2.6 1.1 1.6 0.1 1.2 -0.5 -0.1 -1.2 0.6
Alzheimer’s Disease (including proxy) 6.3 9.1 19.7 1.9 2.9 -3.4 2.9 -4.2 1.5 -4.4 1.0
Crohns Disease (2017) 1.3 2.8 6.5 -1.3 -0.9 2.0 -1.8 2.5 -0.4 0.6 -2.3
Irritable Bowel Disease (IBD) 1.2 2.8 8.4 -1.0 -0.8 2.7 -1.2 2.9 -0.4 1.0 -1.6
Ulcerative Colitis (UC) 1.0 1.9 5.9 -1.0 -1.1 2.2 -0.5 2.4 -0.0 1.2 -0.4
Major Depression (MDD) 0.6 0.7 1.6 -0.9 -0.6 0.8 -1.2 1.3 0.4 0.8 0.5
Reaction Time 0.2 0.5 1.2 -0.1 0.6 -0.7 -0.7 -0.9 1.1 0.1 0.1
Verbal and Numeric Reasoning (VNR) 0.2 0.5 1.4 -0.1 -0.7 1.0 0.3 0.1 1.0 -0.2 1.2
Breast Cancer 0.1 0.4 1.8 -0.0 0.5 -0.2 -0.5 -0.1 1.3 0.6 0.4
Ovarian Cancer 0.8 1.0 3.4 0.6 0.4 -1.4 -0.1 -1.5 0.4 -1.8 0.2
Prostate Cancer 0.7 0.9 2.7 -0.6 -0.5 -1.3 0.4 -1.1 1.6 0.0 -1.1
Age at First Birth 0.7 1.1 2.1 1.3 1.2 -0.7 0.7 -1.2 -1.5 -1.0 -0.2
Bipolar Disorder (2011) 0.5 0.5 2.4 0.6 0.6 -0.4 -0.4 -0.0 0.4 0.4 1.6
Body Mass Index (BMI) (2010) 1.9 2.6 8.0 0.6 0.5 2.3 -0.9 2.8 -0.4 2.1 1.1
Coronary Artery Disease (CAD) 1.6 2.0 4.6 -2.1 -1.8 1.0 -0.8 2.1 0.2 1.4 0.1
Crohns Disease (2012) 0.6 0.9 3.6 -1.2 -0.8 0.4 -0.8 0.7 0.2 0.6 -1.9
Mean Putamen Volume 2.1 2.4 5.1 -2.3 -2.1 0.3 -1.2 1.9 0.6 2.0 -0.4
Fasting Glucose 0.7 0.9 3.3 -0.3 -0.2 1.4 -0.8 1.8 -0.2 0.6 0.7
HbA1C 0.5 0.6 1.7 -0.5 -1.0 -0.2 1.3 -0.3 0.5 -0.7 -0.9
HDL Cholesterol 3.8 6.3 19.2 0.9 0.6 -3.1 1.0 -4.3 -4.4 -0.7 0.1
LDL Cholesterol 0.7 1.1 4.8 -0.8 -0.4 0.8 -0.4 1.3 0.6 2.2 0.2
Lupus 0.6 1.0 3.6 0.7 1.1 0.6 -0.4 0.8 0.4 1.1 1.9
Neuroticism (2016) 1.3 1.9 3.8 -0.2 -0.4 -1.9 1.8 -1.6 -0.8 -1.9 1.0
Primary Biliary Cirrhosis 0.1 0.1 0.7 -0.5 -0.8 0.0 0.2 0.1 0.4 -0.1 -0.0
Rheumatoid Arthritis 1.1 1.5 4.0 1.1 1.3 2.0 -0.6 1.4 0.9 1.4 0.4
Schizophrenia (2014) 1.1 2.5 7.4 -0.4 0.7 -2.7 0.5 -2.7 0.1 -2.0 -0.7
Triglycerides 1.1 1.9 3.8 0.2 0.0 1.8 -0.1 1.9 -0.8 1.8 2.0
Type 2 Diabetes (T2D) (2012) 0.3 0.4 0.9 0.9 0.9 0.8 -0.4 0.4 0.6 0.2 0.3
Ulcerative Colitis 0.8 1.2 4.0 -0.2 -0.2 2.0 0.3 1.8 0.7 1.1 0.4
Blood Eosinophil Count 1.2 9.2 29.4 -0.3 -0.5 4.4 -0.7 4.8 -0.1 5.4 0.6
Blood Platelet Count 0.8 9.0 32.0 -1.5 -0.6 -5.7 -0.2 -5.1 1.5 -2.0 -2.3
Blood Red Count 0.1 1.4 5.6 -0.3 0.1 -2.4 0.2 -1.8 -0.9 0.0 -1.2
Blood White Count 0.1 0.9 4.0 0.7 0.9 -0.0 1.0 -0.0 0.8 2.0 0.9
Heel T-Score 0.6 4.6 14.8 1.6 1.4 -3.2 0.5 -3.9 1.1 -2.4 0.3
BMI 1.0 5.8 13.2 1.4 1.2 2.1 0.6 3.6 -1.3 3.2 3.6
Height 0.2 4.0 10.0 3.2 2.7 0.9 1.1 -1.5 -0.3 -3.1 1.0
Waist Hip Ratio (WHR) 1.2 5.4 17.3 1.5 1.8 -3.0 0.5 -3.1 -1.1 -4.2 -0.8
Systolic Blood Pressure 0.3 1.7 4.0 -1.2 -0.6 -1.6 -1.1 -0.7 -2.0 0.6 -1.8
Smoking Status 2.4 5.8 11.4 3.4 3.3 -0.9 2.3 -2.0 1.8 -1.5 2.9
Allergy or Eczema 0.4 0.9 2.8 0.4 0.4 1.7 0.5 0.7 -0.7 0.6 1.7
Cardiovascular Disease 0.4 1.2 4.0 0.2 0.4 0.6 0.9 1.1 -2.0 1.3 1.3
Hypothyroidism (self reported) 0.4 1.0 2.8 -0.6 -0.8 -1.6 -0.3 -0.6 -1.1 -0.2 -1.7
Respiratory disease 1.1 2.5 6.1 0.1 0.3 1.9 -1.0 2.0 0.8 2.5 2.2
Type 2 Diabetes (T2D) (2018) 0.3 0.6 2.2 0.7 1.0 0.6 -0.1 1.5 1.0 0.2 -0.3
Lung FEV1/FVC ratio 0.7 3.5 13.0 2.2 1.4 0.6 1.6 -0.4 -2.3 0.2 3.6
Lung FVC 0.4 2.2 4.7 1.4 1.3 -1.2 1.0 -1.9 2.2 -1.6 -0.0
Neuroticism 0.5 1.1 3.2 -0.2 0.8 -1.8 -0.5 -1.4 -1.3 -1.0 -0.1
Chronotype (morning person) 1.2 2.9 9.5 0.2 0.9 -1.3 2.9 -1.6 0.1 -3.1 -0.2
Hair Pigment 0.1 3.7 10.5 -0.3 0.3 3.0 -0.7 3.2 1.1 2.7 0.7
Tanning 0.1 1.7 8.9 -0.7 -0.0 -1.3 0.0 -1.6 0.5 -0.1 -3.0
Hand grip strength (left) 1.3 3.3 10.0 -2.0 -1.9 -2.5 0.1 -1.5 -0.3 -0.5 -3.2
Number of treatments/medications taken 0.9 1.6 4.1 0.3 0.0 1.5 0.5 1.9 0.1 1.6 2.0
Average weekly spirits intake 0.6 0.8 1.6 0.8 -0.1 -0.1 0.9 -1.1 1.3 -1.1 0.9
Sensitivity / hurt feelings 0.7 1.2 2.5 1.3 1.6 -0.4 0.1 -1.4 -1.1 -1.3 0.8
Frequency of depressed mood in last 2 weeks 1.4 1.9 6.7 1.6 1.9 -0.4 0.5 -1.0 -0.8 -0.6 2.6
Hearing difficulty/problems: Yes 1.1 1.8 5.7 0.3 0.5 0.0 -2.4 1.2 -0.4 2.2 1.2
Relative age of first facial hair 0.3 0.6 1.6 -1.1 -1.0 -0.1 -1.3 0.3 0.5 0.8 -0.2
Other serious medical condition/disability diagnosed by doctor 0.5 0.7 1.6 0.3 0.2 1.2 -1.2 1.3 -0.2 0.8 0.2
Ever used hormone-replacement therapy (HRT) 0.5 0.6 1.8 -1.1 -0.5 0.4 0.2 0.9 1.4 0.6 -0.2
Ever had hysterectomy (womb removed) 1.5 1.7 7.3 0.3 1.0 -1.1 1.3 -1.3 0.7 -2.7 0.2
Systolic blood pressure, automated reading 0.2 0.6 3.7 -0.3 0.0 -0.3 0.1 0.5 -1.9 1.0 0.1
Eye problems/disorders: Diabetes related eye disease 0.8 0.9 2.4 -0.8 -0.9 0.3 -1.5 1.1 -0.4 1.2 -0.8
Angina 0.6 0.8 2.4 -1.1 -1.0 -0.6 -1.6 0.4 -0.9 0.5 -0.6
Medication for hormone replacement therapy 0.4 0.4 1.1 -1.1 -0.7 -0.7 -0.4 -0.6 -0.5 0.3 0.7
Vitamin and mineral supplements 1.3 1.7 5.2 -1.9 -1.4 -1.4 -0.4 -0.0 -0.8 0.4 -2.3
Supplements: Zinc 1.2 1.3 3.2 1.3 1.3 -0.4 0.1 -1.5 1.8 -0.9 0.9
Medication: Co-codamol 1.4 1.6 4.1 1.7 2.0 0.4 1.1 -0.6 1.2 -1.1 1.3
Medication: Metformin 0.5 0.7 2.0 0.0 0.2 0.8 1.4 0.7 1.2 -0.9 0.1
Diabetes (father) 1.8 2.2 5.4 0.5 1.2 1.0 -1.8 1.3 -2.3 2.1 0.8
Diabetes (mother) 0.9 1.2 3.3 1.8 1.8 1.0 0.1 1.0 0.1 0.4 1.0
Severe depression (siblings) 0.5 0.6 1.9 0.3 -0.1 -1.4 -0.7 -0.9 0.9 -0.7 -0.3
Pack years adult smoking proportion 3.2 4.9 12.5 1.4 1.8 -3.4 1.5 -3.5 -0.4 -2.7 0.5
Impedance of leg (right) 0.5 2.2 11.1 1.2 1.0 -0.2 0.9 -1.6 -0.7 -3.3 -0.6
Leg fat-free mass (left) 0.2 1.0 2.9 1.1 1.1 -0.1 0.3 0.8 0.1 1.7 1.4
Trunk fat percentage 1.5 5.9 15.1 3.2 2.6 1.6 1.9 2.2 -1.6 0.9 3.9
Hand grip strength (right) 0.8 2.2 5.8 -2.0 -1.8 -1.9 -0.4 -0.6 -0.9 -0.1 -2.4
Townsend deprivation index at recruitment 0.5 0.6 1.8 -0.5 -0.3 -1.2 -1.4 -0.6 -0.7 -0.3 -0.6
Current tobacco smoking 2.1 3.4 7.3 2.6 2.7 -0.3 1.7 -1.7 0.3 -2.0 1.8
Average weekly fortified wine intake 1.8 2.1 5.4 -2.0 -2.3 -1.9 0.5 -1.4 0.0 -1.2 0.7
Maternal smoking around birth 1.3 1.9 4.2 1.5 2.0 -1.8 -0.4 -1.9 0.0 -1.3 -0.4
Fed-up feelings 0.5 0.8 2.3 0.6 1.0 -1.5 -0.2 -1.5 -0.6 -0.6 -0.1
Frequency of unenthusiasm / disinterest in last 2 weeks 5.8 7.7 14.8 3.3 3.0 -1.8 1.6 -3.2 -1.7 -3.9 2.9
Relative age voice broke 0.5 0.7 3.1 0.4 0.3 -0.9 -0.1 -0.8 1.8 -0.2 1.0
Taking other prescription medications 1.0 1.6 7.4 0.8 0.4 1.2 0.3 1.4 0.4 0.7 2.7
Age when periods started (menarche) 1.4 3.3 8.9 -0.8 -1.6 3.0 -1.4 2.7 -0.6 2.1 0.7
Bilateral oophorectomy (both ovaries removed) 2.6 3.0 8.2 -0.8 0.2 -2.3 -0.8 -2.2 -1.0 -1.8 -2.9
Heel bone mineral density (BMD) T-score, automated (left) 0.6 1.3 3.3 0.8 0.2 -1.3 1.1 -1.8 1.0 -0.6 1.5
Tinnitus: Yes, but not now, but have in the past 0.6 0.6 1.7 -0.9 -1.3 0.0 0.6 0.6 -0.4 1.0 -0.7
Qualifications: CSEs or equivalent 1.8 2.4 4.9 1.9 1.8 -1.4 0.8 -2.2 -0.2 -2.1 0.6
Serious illness, injury or assault to yourself 0.1 0.1 0.3 -0.2 -0.4 0.2 -0.1 0.1 -0.6 -0.6 0.4
High blood pressure 0.3 0.9 3.1 -1.0 -0.9 -0.7 1.4 0.2 -1.8 0.1 0.2
Hayfever, allergic rhinitis or eczema 0.7 1.6 5.3 1.4 1.6 1.6 0.5 0.6 0.1 0.6 2.3
Multivitamins +/- minerals 1.6 2.0 5.0 1.9 1.5 -0.2 -0.0 -1.6 1.0 -1.3 2.2
Stomach or abdominal pain in last month 1.9 2.3 6.0 1.0 1.2 -2.1 -0.2 -2.4 -0.8 -2.0 -1.0
Supplements: Glucosamine 2.0 2.6 8.8 0.4 0.7 3.0 -0.7 2.3 2.0 1.4 -0.1
Diverticular disease/diverticulitis (self-reported) 0.8 0.9 3.0 -0.3 -0.9 0.1 0.8 -0.2 1.7 -1.4 0.8
Medication: Atenolol 1.8 2.3 5.1 -2.0 -2.2 -1.2 0.2 -0.1 -1.6 -0.3 -2.3
Medication: Levothyroxine sodium 1.0 1.7 3.9 -0.7 -1.2 -1.2 1.5 -0.9 -2.0 -1.0 -1.4
Sitting height 0.1 0.4 0.9 0.7 0.3 -0.2 -0.2 -0.6 -1.0 0.6 -0.8
Chronic bronchitis/emphysema (father) 2.6 3.0 7.1 -2.7 -2.4 -0.4 -2.3 1.2 -0.8 1.5 -1.1
High blood pressure (mother) 0.6 0.8 4.1 0.6 0.7 0.4 -0.6 0.8 -2.0 0.5 0.5
Body mass index (BMI) 1.0 4.4 10.1 2.4 2.4 1.0 0.7 2.4 -1.3 2.1 3.2
Impedance of leg (left) 0.4 1.8 10.4 0.9 0.7 0.1 0.6 -1.3 -0.8 -3.2 -0.5
Leg predicted mass (left) 0.2 1.0 3.3 1.1 1.1 -0.1 0.2 0.8 0.2 1.8 1.3
Trunk fat mass 1.1 4.8 10.9 3.0 2.5 1.3 1.6 2.1 -1.4 1.2 3.3
Waist circumference 1.3 4.6 10.8 3.2 3.1 0.7 1.0 1.5 -1.5 0.9 3.3
Number of incorrect matches in round 0.8 1.3 3.4 -1.8 -1.6 -1.0 -1.6 -0.0 -0.8 -0.2 -0.5
Past tobacco smoking 0.6 1.1 3.0 -1.0 -0.7 0.2 -1.3 -0.2 -1.7 -0.7 -1.4
Alcohol usually taken with meals 0.4 0.7 3.3 -1.1 -1.8 0.4 -0.2 0.9 -0.1 0.2 0.3
Nervous feelings 1.8 3.4 10.1 1.8 2.1 -1.2 1.8 -1.8 -0.8 -3.2 1.1
Frequency of tenseness / restlessness in last 2 weeks 0.8 1.2 5.0 0.1 -0.2 -1.2 0.4 -0.9 -2.2 -1.2 0.9
Hearing difficulty/problems with background noise 0.6 0.9 2.6 -0.2 0.0 0.6 -1.4 1.5 -0.1 1.6 0.3
Hair/balding pattern: Pattern 2 0.2 0.2 0.7 0.2 0.6 -0.1 0.4 0.5 -0.8 0.6 0.1
Had menopause 0.9 1.1 4.0 -0.5 -0.7 1.7 0.0 2.0 0.6 1.0 0.4
Had other major operations 1.0 1.2 3.3 0.8 1.1 1.0 0.7 0.8 1.8 -0.5 1.5
Forced vital capacity (FVC) 0.6 2.4 5.1 1.3 1.2 -0.7 1.3 -2.2 2.1 -1.7 -1.2
Heel bone mineral density (BMD) T-score, automated (right) 0.5 1.2 4.4 0.6 0.1 -1.5 0.7 -2.1 0.4 -1.4 0.6
Ever unenthusiastic/disinterested for a whole week 0.3 0.4 0.8 -0.5 -0.7 0.6 -0.3 0.8 -0.5 0.9 0.2
Qualifications: None of the above 0.8 1.8 4.8 1.3 1.4 -2.2 -0.4 -1.9 0.0 -1.2 0.7
Financial difficulties in last 2 years 0.6 0.8 4.0 0.4 0.5 -0.7 -0.7 -0.5 -0.9 -0.1 2.0
Mouth/teeth dental problems 0.4 0.7 1.8 0.2 0.2 1.2 -0.7 1.3 -0.3 0.9 -0.9
Heart attack 1.2 1.5 4.4 -1.2 -0.6 -1.6 -1.1 -0.5 -2.1 0.6 -1.1
Allergy 1.3 2.9 6.8 -1.4 -1.8 -2.3 0.3 -1.5 -0.2 -1.9 -2.6
Pain all over the body in last month 0.6 0.6 1.9 0.1 0.2 -0.7 -1.4 -0.3 -0.8 0.0 1.3
Diabetes (self-reported) 0.6 0.9 3.5 0.5 0.9 1.1 -0.4 1.9 0.7 0.7 0.3
Hayfever/allergic rhinitis (self-reported) 0.4 0.6 2.5 0.4 0.7 0.5 1.1 0.1 0.4 0.1 1.6
Medication: Ramipril 0.3 0.4 1.3 -1.2 -0.9 -0.6 0.8 0.1 -0.1 -0.2 -0.5
Medication: Simvastatin 2.0 2.9 6.2 -1.6 -1.7 1.5 -1.3 2.3 -1.0 2.5 0.9
Fluid intelligence score 0.2 0.4 1.0 -0.6 -1.0 0.6 -0.5 0.5 1.0 -0.5 0.2
Illnesses of siblings 0.2 0.2 0.7 -0.1 -0.4 -0.2 -0.0 -0.9 -0.6 0.7 -0.3
Neuroticism score 0.7 1.6 3.5 0.4 1.2 -1.7 0.6 -1.9 -1.3 -1.5 0.5
Weight 0.6 3.1 6.2 2.5 2.4 0.7 0.8 1.6 -1.2 1.4 2.4
Impedance of arm (right) 0.5 2.3 9.1 1.1 0.4 0.5 1.6 -1.6 0.8 -3.0 1.3
Arm fat percentage (right) 1.5 5.8 17.4 3.2 2.7 1.2 1.6 1.9 -1.3 1.4 4.2
Trunk fat-free mass 0.1 0.5 1.6 0.8 1.1 -0.5 -0.4 0.2 -0.0 1.3 -0.1
Hip circumference 1.2 5.1 11.7 2.4 2.2 1.6 0.6 2.6 -1.2 2.7 3.4
Time employed in main current job 0.8 0.9 4.0 0.3 0.4 1.0 -2.0 1.2 0.0 0.8 -0.3
Alcohol intake versus 10 years previously 0.9 1.3 3.8 1.4 0.9 2.0 0.7 0.6 1.4 -1.1 0.4
Father’s age at death 0.9 1.2 3.1 1.5 0.9 0.8 0.5 -0.1 1.6 -0.2 1.8
Worrier / anxious feelings 0.5 0.9 2.2 0.8 1.5 0.8 0.5 0.5 -0.7 -1.2 1.1
Frequency of tiredness / lethargy in last 2 weeks 3.6 5.9 10.6 3.2 3.1 -1.1 0.9 -2.0 -2.8 -1.8 3.2
Falls in the last year 0.6 0.8 2.6 1.0 0.8 -0.4 -0.0 -0.9 -1.6 -0.8 0.4
Hair/balding pattern: Pattern 3 0.1 0.1 0.4 -0.0 -0.3 -0.3 0.3 -0.2 -0.6 -0.1 -0.0
Number of live births 1.0 1.5 4.6 -2.1 -1.4 0.0 -1.3 0.8 -0.1 1.3 -1.1
Forced expiratory volume in 1-second (FEV1) 0.7 2.3 7.0 1.5 1.2 -1.0 1.6 -2.6 1.0 -1.8 -0.4
Pulse rate 0.4 0.6 3.3 0.6 0.6 -0.3 0.6 -0.1 1.8 -0.4 -0.4
Happiness 0.2 0.3 1.3 0.2 0.5 -0.7 0.4 -1.2 -0.1 -0.1 0.2
Noisy workplace 0.3 0.4 1.2 0.7 0.6 -1.1 0.1 -0.6 0.5 0.4 0.4
Qualifications: A levels/AS levels or equivalent 1.3 2.9 5.6 -2.0 -2.2 1.9 -0.5 2.4 0.6 2.0 -0.9
Serious illness, injury or assault of a close relative in last 2 years 0.2 0.2 0.7 0.3 0.2 0.3 0.8 0.3 0.5 0.3 0.8
Mouth/teeth dental problems: Dentures 0.3 0.5 1.7 -0.4 -0.4 -0.8 -0.6 -0.6 1.3 0.0 -0.3
Asthma 0.8 1.6 3.8 -0.7 0.0 1.4 -0.5 1.8 0.4 2.0 1.6
Medication: Ibuprofen (e.g. Nurofen) 1.5 1.9 4.2 1.8 1.5 2.1 0.8 1.2 -0.4 1.0 1.3
Medication: Cholesterol lowering 1.8 2.8 6.1 -0.3 -0.5 1.7 -0.9 2.5 -2.0 2.3 1.7
Depression (self-reported) 0.6 0.8 2.2 1.2 1.5 -0.5 0.1 -1.0 0.8 -0.7 0.3
Medication: Lansoprazole 1.5 1.7 4.4 1.7 2.1 -0.7 -0.0 -1.4 -0.9 -1.7 0.5
Prospective memory result 0.7 0.8 2.2 0.8 1.1 -0.9 -0.9 -0.6 0.4 1.5 0.7
Lung cancer (father) 0.5 0.5 1.3 0.2 -0.1 -1.1 -0.5 -1.1 -1.0 -0.6 0.1
Illnesses of mother 0.1 0.2 1.2 0.1 -0.0 0.2 -0.2 -0.4 1.1 -0.1 0.2
Forced expiratory volume in 1-second (FEV1), Best measure 0.8 2.6 9.0 1.6 1.2 -1.4 1.5 -3.0 0.9 -1.6 0.6
Pulse wave Arterial Stiffness index 0.2 0.2 0.6 0.1 0.6 0.4 0.5 0.2 0.6 0.4 -0.8
Impedance of arm (left) 0.4 1.9 7.8 0.7 0.1 0.3 1.6 -1.6 0.3 -2.8 1.1
Arm fat mass (right) 1.3 5.2 12.4 3.2 3.0 1.1 1.3 1.9 -1.3 1.3 3.5
Trunk predicted mass 0.1 0.5 1.8 0.7 1.0 -0.5 -0.5 0.2 0.0 1.3 -0.1
Standing height 0.1 0.9 2.1 0.7 0.6 -0.5 0.4 -1.4 0.3 -1.4 -1.2
Length of working week for main job 1.0 1.1 2.7 -1.0 -0.6 -0.8 -1.0 0.4 -1.1 1.4 -1.6
Exposure to tobacco smoke at home 0.2 0.2 0.7 -0.3 0.0 0.1 -0.9 -0.6 0.7 -0.0 -0.2
Breastfed as a baby 2.5 3.1 8.4 -0.3 -0.8 2.7 -1.1 2.6 0.0 2.9 0.0
Tense / ‘highly strung’ 1.8 3.0 9.7 -0.1 0.3 -3.1 0.4 -2.6 -0.1 -2.4 -1.1
Seen doctor (GP) for nerves, anxiety, tension or depression 0.4 0.7 1.6 0.8 1.2 0.1 1.2 0.6 -0.1 -1.0 0.6
Hair/balding pattern: Pattern 4 0.2 0.4 1.2 0.4 -0.1 0.9 0.1 -0.5 1.0 -1.1 -0.1
Birth weight of first child 1.2 2.2 6.0 0.6 0.4 -1.4 2.5 -1.7 0.6 -2.3 -0.3
Peak expiratory flow (PEF) 1.1 2.4 5.7 2.1 1.9 -0.9 1.4 -2.4 0.0 -1.7 -0.2
Pulse wave reflection index 0.1 0.1 0.3 -0.1 -0.3 0.3 0.2 -0.2 0.3 0.0 -0.6
Ever highly irritable/argumentative for 2 days 1.0 1.2 3.5 1.9 1.7 1.0 0.2 0.3 0.2 0.8 1.3
Loud music exposure frequency 0.4 0.4 0.8 0.5 0.5 -0.9 -0.8 -0.8 -0.5 0.5 0.6
Qualifications: O levels/GCSEs or equivalent 0.9 1.5 3.0 -1.2 -1.5 1.5 1.3 1.7 -0.2 0.7 0.8
Mouth/teeth dental problems: Bleeding gums 0.7 1.0 2.8 -0.5 -0.2 0.9 -0.8 1.5 0.6 1.7 0.7
Blood clot in the leg (DVT) 0.7 0.9 2.6 0.5 0.8 -0.9 0.5 -1.2 -0.4 -1.6 -1.1
Medication: Paracetamol 2.7 4.5 10.6 2.9 2.8 3.3 0.9 2.2 -0.0 0.4 2.0
Headache pain in last month 0.6 1.0 2.7 0.6 0.3 1.6 1.3 0.4 -0.4 -0.7 1.5
Medication for cholesterol, blood pressure or diabetes 2.7 4.5 10.6 -0.3 -0.0 -2.8 -0.3 -3.2 2.7 -2.2 -2.2
Glaucoma (self-reported) 2.2 2.5 8.3 -1.7 -1.9 -1.1 -2.9 -0.1 0.4 1.4 -1.4
Gout (self-reported) 0.8 1.2 3.1 1.7 1.8 -0.5 0.6 -1.2 -0.7 -0.8 0.2
Hypothyroidism/myxoedema (self-reported) 0.5 1.0 3.2 -0.5 -0.8 -1.5 0.1 -0.5 -1.8 -0.5 -1.0
Medication: Amlodipine 0.4 0.6 3.0 -0.3 -0.6 0.4 0.4 0.8 -1.7 0.8 -0.1
Medication: Ventolin 100micrograms inhaler 1.8 2.3 4.7 -1.6 -1.4 0.7 -2.1 1.9 0.5 2.2 -0.7
Birth weight 0.4 0.9 2.5 -0.1 -0.3 -1.2 -0.3 -0.7 1.6 0.9 1.5
Chronic bronchitis/emphysema (mother) 1.0 1.1 5.2 0.0 -0.4 0.2 1.1 -0.7 1.3 -2.3 0.4
High blood pressure (siblings) 0.5 0.7 2.7 -0.3 -0.1 0.1 1.5 0.4 -0.3 -1.6 0.5
Forced vital capacity (FVC), Best measure 0.6 2.3 5.8 1.5 1.4 -1.1 1.3 -2.4 2.0 -1.3 0.0
Body fat percentage 1.5 5.8 14.1 3.2 2.7 1.5 1.7 2.3 -1.7 1.2 3.8
Leg fat percentage (right) 1.2 4.4 10.1 3.1 2.9 0.3 1.3 1.5 -1.5 0.7 3.2
Arm fat-free mass (right) 0.2 0.8 3.5 0.5 0.8 -0.1 -0.4 1.2 -0.7 1.9 0.1
Exposure to tobacco smoke outside home 0.9 1.2 3.2 1.6 1.6 -0.4 0.5 -0.8 0.5 -0.5 1.8
Comparative body size at age 10 0.2 0.6 1.9 1.0 0.8 0.5 0.5 0.9 -1.4 -0.0 0.0
Number of full brothers 0.9 1.2 4.1 0.6 1.4 -0.5 -2.0 0.3 1.1 1.2 0.0
Worry too long after embarrassment 0.5 0.8 2.0 -0.1 0.0 -1.2 0.5 -1.2 -0.8 -1.4 1.0
Seen a psychiatrist for nerves, anxiety, tension or depression 2.0 2.6 5.4 1.9 1.6 -0.9 1.6 -1.6 0.3 -2.3 1.8
Wheeze or whistling in the chest in last year 0.7 1.3 4.8 1.3 1.2 1.3 0.2 0.7 -0.8 -0.0 2.2
Number of children fathered 0.5 0.6 1.3 0.2 -0.3 1.2 1.0 0.7 -1.1 -0.6 0.6
Reason for reducing amount of alcohol drunk: Health precaution 2.5 2.9 6.6 -2.6 -2.3 1.4 0.6 1.3 0.5 1.1 -2.5
Age at first live birth 0.4 0.7 2.7 0.4 -0.3 1.1 1.6 0.4 1.0 -0.1 0.6
Pulse wave peak to peak time 0.2 0.3 0.5 -0.1 -0.5 -0.5 -0.4 -0.4 -0.7 -0.5 0.7
Health satisfaction 0.1 0.1 0.2 -0.2 -0.5 0.4 0.4 0.0 0.3 0.1 -0.3
Shortness of breath walking on level ground 0.4 0.5 1.5 -1.0 -1.2 0.0 -0.2 0.7 0.1 0.7 -0.3
Qualifications: College or University degree 0.4 1.1 2.6 -1.1 -1.0 1.1 0.1 0.9 1.2 1.6 -0.8
Eye problems/disorders: None of the above 2.2 2.5 7.1 2.3 2.7 0.9 1.7 -0.1 -0.1 -1.5 1.3
Mouth/teeth dental problems: Loose teeth 0.7 0.8 3.4 0.0 0.3 -1.8 0.0 -1.4 0.8 -0.0 -0.5
Emphysema/chronic bronchitis 0.7 0.8 2.1 1.4 1.0 1.0 0.7 0.6 0.3 0.7 0.8
Medication for pain relief, constipation, heartburn 1.6 2.7 7.3 -0.5 -0.5 -2.1 1.0 -2.7 -0.1 -2.1 -2.0
Neck or shoulder pain in last month 0.3 0.5 1.6 -0.8 -0.5 -0.2 -0.6 -0.2 -0.7 0.6 -1.3
Medication: Blood pressure 1.7 3.1 9.2 -0.6 -1.0 2.1 1.6 2.4 -3.0 1.0 0.7
Angina (self-reported) 1.0 1.4 3.4 -1.5 -1.3 -0.6 -1.8 0.5 -1.0 1.0 -0.9
Migraine (self-reported) 1.6 2.0 3.6 1.9 1.8 -0.1 1.3 -1.4 -0.9 -1.5 1.6
Medication: Ibuprofen 1.8 2.1 4.8 1.9 1.4 2.2 1.5 1.3 0.2 0.7 1.5
Medication: Allopurinol 1.0 1.3 3.6 1.0 0.8 -1.1 1.0 -1.9 -1.5 -0.9 -0.3
Medication: Omeprazole 0.5 0.6 1.5 -0.9 -1.2 0.6 -0.6 1.0 -0.0 0.8 0.4
Medication: Seretide 50 evohaler 0.3 0.4 1.1 0.3 0.6 1.1 -0.0 0.4 -0.6 0.7 0.5
Mean time to correctly identify matches 0.2 0.3 0.7 -0.6 0.1 -0.2 -0.9 -0.2 0.8 0.7 0.2
Heart disease (mother) 4.3 5.3 12.7 -1.7 -1.1 1.6 -2.3 3.4 -0.5 3.6 -2.4
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.3 0.3 0.7 -0.1 -0.7 0.8 -0.2 0.2 -0.7 0.8 0.3
Whole body fat mass 1.2 4.8 11.3 3.1 2.7 1.0 1.4 2.0 -1.4 1.3 3.4
Leg fat mass (right) 1.0 4.0 8.7 2.9 2.7 0.6 1.0 1.8 -1.2 1.2 3.0
Arm predicted mass (right) 0.2 0.9 4.4 0.4 0.8 -0.3 -0.8 1.1 -0.6 2.1 -0.0
Pulse rate, automated reading 0.8 2.7 4.2 1.8 2.0 -2.1 1.4 -1.7 1.3 -1.9 0.6
Alcohol intake frequency. 2.2 5.0 10.8 3.3 2.9 0.1 1.6 -1.2 1.7 -2.7 2.6
Comparative height size at age 10 0.1 0.6 1.7 0.1 -0.1 -0.7 0.6 -1.1 0.5 -1.3 -0.8
Number of full sisters 0.9 1.1 2.8 1.3 1.7 -1.0 -0.2 -0.9 -0.8 -1.0 0.7
Suffer from ‘nerves’ 3.1 4.9 11.1 1.6 1.4 -2.1 2.2 -3.3 -1.8 -3.3 0.6
Overall health rating 0.8 1.7 3.8 1.7 1.5 0.1 0.8 0.5 -1.9 0.3 1.8
Chest pain or discomfort 0.8 1.1 5.2 0.5 0.1 -0.8 -0.6 -0.3 -1.2 0.8 2.3
Had major operations 0.8 0.9 2.9 0.1 -0.0 1.2 0.7 1.3 -1.0 1.7 -0.2
Age at last live birth 0.5 0.7 1.2 -0.7 -1.0 1.1 1.1 0.4 1.1 0.3 -0.4
Family relationship satisfaction 2.2 2.7 4.2 2.0 1.9 -0.5 1.9 -2.0 1.9 -1.5 0.1
Leg pain on walking 0.4 0.5 1.7 0.3 -0.4 -0.7 0.3 -1.0 -0.1 -1.3 -0.6
Qualifications: NVQ or HND or HNC or equivalent 0.5 0.6 2.0 -0.1 -0.2 -1.0 0.1 -1.4 -0.2 -1.0 0.7
Commuting to job workplace: Car/motor vehicle 0.3 0.4 0.7 0.6 0.8 0.6 -0.3 0.4 -0.5 0.9 0.7
Illness, injury, bereavement, stress in last 2 years 0.2 0.3 0.9 -0.3 -0.1 0.6 0.8 0.4 -0.4 0.0 -1.0
Medication: Aspirin 3.5 4.7 10.4 -2.3 -1.7 0.8 -3.0 2.9 -0.2 3.2 -0.7
Supplements: Vitamin C 1.2 1.4 4.4 1.7 1.3 0.4 2.1 -0.7 -0.5 -0.7 0.8
Knee pain experienced in last month 0.7 1.0 3.2 1.4 1.8 1.3 -0.2 1.0 0.1 0.6 -0.1
Hypertension (Self-reported) 0.3 0.7 3.2 -0.7 -0.6 -0.2 0.9 0.7 -1.8 0.6 0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.5 0.6 1.6 -1.0 -0.8 -0.8 -0.8 -0.3 0.4 1.3 -0.5
Illnesses of father: Heart disease 1.3 1.8 4.2 -0.9 -0.7 1.3 -1.5 2.1 -0.7 2.0 0.3
Illnesses of siblings: Diabetes 0.1 0.1 0.4 -0.1 0.2 -0.6 -0.5 -0.1 0.1 -0.0 0.3
Smoking status: Previous 0.6 0.8 1.8 -0.2 -0.5 0.4 0.9 1.2 0.8 1.3 1.2
Forced expiratory volume in 1-second (FEV1), predicted 0.3 0.6 3.3 -0.3 -0.4 -0.5 -0.8 -0.7 -1.8 -0.3 0.5
Whole body fat-free mass 0.1 0.7 3.0 0.8 1.0 -0.2 -0.3 0.7 0.0 1.7 0.5
Leg fat-free mass (right) 0.2 0.8 3.5 0.7 0.8 -0.0 -0.1 0.8 0.2 1.9 1.2
Arm fat percentage (left) 1.4 5.6 16.2 3.0 2.6 1.3 1.6 2.1 -1.4 1.5 4.0
Average weekly red wine intake 1.8 2.6 9.2 -2.0 -1.5 -0.1 -2.0 0.4 -0.3 1.1 -3.0
Handedness (chirality/laterality): Left-handed 0.4 0.5 2.0 -0.1 -0.8 -0.7 1.4 0.1 0.3 -0.1 -0.9
Mood swings 1.2 2.2 4.3 1.6 2.0 -1.0 1.4 -1.5 -0.1 -2.1 1.2
Loneliness, isolation 1.7 2.4 5.0 1.2 1.6 -1.4 1.5 -2.2 0.6 -2.2 0.6
Long-standing illness, disability or infirmity 0.9 1.4 4.0 2.0 1.9 0.1 0.6 -0.1 -0.5 -0.0 1.7
Ever had bowel cancer screening 0.4 0.5 1.7 0.0 0.3 -0.8 0.3 -1.0 1.3 -0.6 -0.3
Diabetes diagnosed by doctor 0.5 0.9 2.8 0.9 1.4 1.0 -0.4 1.7 0.4 0.4 0.5
Ever had stillbirth, spontaneous miscarriage or termination 2.5 2.7 6.1 2.2 2.5 -0.2 2.0 -1.6 0.4 -1.9 0.1
Friendships satisfaction 2.0 2.5 13.6 0.2 0.8 -1.0 -0.3 -1.8 3.7 -0.5 -1.1
Qualifications: nursing, teaching 0.7 1.1 3.1 -0.1 -0.1 1.8 0.5 1.8 -0.9 1.0 -0.2
Commuting to job workplace: Walk 0.7 0.7 2.3 0.7 0.3 0.7 1.5 0.2 0.8 -1.2 -0.5
Eye problems/disorders: Cataract 0.8 1.0 2.6 -1.4 -1.6 -0.2 -0.6 0.6 -0.7 1.3 -0.6
Mouth/teeth dental problems: Mouth ulcers 0.9 1.4 3.9 -0.9 -1.1 -1.5 0.6 -2.0 0.1 -1.5 -0.2
Medication for cholesterol 0.7 1.0 4.2 2.0 1.5 0.1 -0.3 -0.9 0.1 -0.9 0.2
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.7 0.9 3.0 0.3 0.2 -1.1 1.7 -1.0 0.6 -1.0 0.5
Back pain experienced in last month 1.6 2.4 8.6 2.9 2.6 -0.0 0.3 -1.0 -0.8 -0.9 1.1
Mineral and other dietary supplements 0.5 0.7 1.5 -0.9 -1.2 -1.1 0.8 -0.8 0.3 -0.8 0.2
Breast cancer (self-reported) 0.6 0.7 2.9 -0.5 -0.3 0.6 -1.7 0.8 -0.4 1.1 -0.3
Asthma (self-reported) 1.0 2.0 5.3 -0.6 0.0 1.6 -0.7 2.1 0.6 2.3 1.6
Osteoporosis (self-reported) 0.8 1.0 4.0 -0.6 -0.4 1.5 -0.7 2.0 0.3 0.9 0.2
Osteoarthritis (self-reported) 0.6 0.7 1.9 -1.4 -1.3 -0.9 0.3 -0.2 0.2 0.2 -1.1
Medication: Aspirin 4.3 5.7 11.4 -2.8 -2.3 0.8 -3.1 3.1 -0.4 3.4 -1.0
Medication: Gliclazide 0.5 0.6 3.1 -0.6 -0.3 -0.7 0.1 -0.3 0.6 -0.0 -1.8
Illnesses of father: None of the above (group 1) 1.6 2.0 5.1 0.3 -0.5 -1.2 1.2 -2.2 0.9 -2.3 -1.4
Smoking status: Current 1.8 2.9 6.7 2.5 2.6 -0.0 1.3 -1.5 0.5 -1.9 1.7
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.6 1.3 2.9 0.9 0.8 -0.6 1.3 -1.3 1.7 -1.2 1.0
Whole body water mass 0.1 0.7 3.0 0.9 1.1 -0.1 -0.2 0.7 -0.1 1.7 0.4
Leg predicted mass (right) 0.2 0.9 3.7 0.8 0.8 0.1 -0.1 0.9 0.2 1.9 1.2
Arm fat mass (left) 1.1 4.5 10.8 2.8 2.6 1.0 1.0 2.0 -1.5 1.6 3.3
Number of self-reported non-cancer illnesses 0.6 1.0 3.2 1.3 1.2 0.3 1.2 0.5 -0.4 0.1 1.8
Average weekly champagne plus white wine intake 0.8 1.1 2.5 1.5 0.8 0.2 1.2 -0.9 0.9 0.0 1.6
Miserableness 0.5 0.9 1.7 0.4 0.6 -1.2 0.2 -1.3 -1.1 -1.1 0.9
Guilty feelings 0.2 0.3 1.2 -1.1 -0.8 -0.4 0.2 -0.2 0.4 0.3 0.3
Wears glasses or contact lenses 2.0 2.3 5.0 0.1 -0.3 1.8 0.6 2.1 1.5 1.7 2.2
Ever taken oral contraceptive pill 0.4 0.5 2.0 0.3 0.2 0.5 0.4 -0.0 1.4 0.7 0.8
Hearing aid user 0.3 0.3 0.9 -0.8 -1.0 -0.3 0.3 0.3 0.9 0.0 -0.0
Mother’s age at death 3.7 4.6 10.1 -1.5 -1.4 2.5 -2.2 3.1 -0.8 3.2 -1.2
Financial situation satisfaction 0.2 0.3 1.0 -0.2 -0.5 -0.5 -0.2 -0.8 -0.5 0.0 1.0
Tinnitus: Yes, now most or all of the time 1.2 1.4 3.3 -0.6 -0.3 1.1 -1.1 1.8 0.6 1.7 -1.4
Commuting to job workplace: Public transport 0.2 0.3 0.8 0.7 0.1 -0.1 0.5 -0.5 0.9 -0.7 0.3
Eye problems/disorders: Glaucoma 2.1 2.5 6.5 -1.6 -1.6 -0.9 -2.5 -0.1 1.6 1.2 -1.8
Medication: Blood pressure 0.5 1.0 2.7 -1.6 -1.3 -1.2 -0.0 0.2 -0.3 1.0 -1.0
Pain type(s) experienced in last month: Hip pain 0.3 0.4 2.0 0.1 0.4 0.1 0.8 0.4 -1.4 -0.5 -0.3
Supplements: Fish oil (including cod liver oil) 0.3 0.3 0.7 0.8 0.9 0.2 -0.5 0.3 -0.2 0.7 0.5
High cholesterol (Self-reported) 2.0 3.6 11.4 -1.2 -1.5 1.3 -1.1 2.7 -1.8 3.4 0.8
Medication: Bendroflumethiazide 2.2 3.3 6.2 -1.7 -1.4 1.4 0.8 2.5 -2.3 2.4 -1.5
Medication: Paracetamol 1.8 2.8 6.5 2.2 2.0 2.5 1.4 1.7 0.5 -0.3 1.5
Medication: Lisinopril 0.9 1.1 2.3 0.1 -0.1 1.5 0.2 1.4 -1.4 1.4 0.9
Medication: Atorvastatin 4.1 5.1 16.1 -1.6 -1.5 2.9 -0.8 4.0 -2.0 2.3 -1.2
Illnesses of father: High blood pressure 1.1 1.4 4.8 -1.7 -1.2 -0.2 -0.3 1.2 -0.3 2.2 0.1
Alcohol drinker status: Never 0.2 0.2 0.6 0.3 0.2 0.3 -0.8 0.2 0.3 -0.7 0.6
Ever smoked 0.7 1.2 2.8 1.0 0.8 -0.5 1.5 -0.4 1.7 0.5 1.4
Basal metabolic rate 0.2 1.1 2.7 1.4 1.5 -0.1 0.0 0.8 -0.3 1.6 1.0
Leg fat percentage (left) 1.0 3.5 8.4 2.6 2.4 0.4 1.0 1.7 -1.4 1.0 2.9
Arm fat-free mass (left) 0.2 1.0 4.4 0.8 1.1 -0.1 -0.8 1.1 -0.3 2.1 0.2
Number of operations (self-reported) 0.6 0.9 1.5 0.6 0.7 1.1 1.2 1.2 -1.0 0.4 1.1
Average weekly beer plus cider intake 0.6 0.9 2.8 0.1 0.9 -1.7 -1.2 -0.6 -1.1 -0.6 -0.4
Irritability 0.9 1.6 4.1 -1.4 -0.7 -2.0 -1.2 -0.7 -1.0 -0.1 -1.8
Risk taking 0.6 0.9 2.9 0.3 0.2 -1.4 1.7 -1.3 0.5 -0.2 -0.1
Ever had prostate specific antigen (PSA) test 0.5 0.6 3.1 0.6 0.2 0.6 1.7 -0.4 -0.0 -0.6 0.1
Fractured/broken bones in last 5 years 0.3 0.4 1.5 -0.2 -0.3 0.5 0.3 0.4 -1.2 -1.1 0.0
Age started oral contraceptive pill 2.4 2.9 5.6 -1.8 -1.3 1.3 -1.9 2.4 1.0 1.9 -1.8
Diastolic blood pressure, automated reading 0.5 1.5 3.9 1.3 2.0 -1.3 1.0 -1.5 -0.8 -0.5 0.7
Ever depressed for a whole week 0.5 0.6 2.0 0.1 0.0 1.4 0.6 1.2 1.1 -0.2 0.1
Unable to work because of sickness or disability 1.7 2.2 5.9 1.3 0.8 -1.4 1.5 -2.4 -1.0 -1.9 0.8
Commuting to job workplace: Cycle 0.4 0.5 1.4 -0.4 -0.5 0.1 0.9 -0.2 0.5 -1.2 -1.0
Myopia 0.3 0.4 1.0 -0.0 0.2 0.9 -0.4 1.0 0.5 0.8 0.6
Vascular/heart problems diagnosed by doctor 0.4 1.1 4.1 1.4 1.1 1.0 -0.8 -0.3 2.0 -0.4 0.1
Cholesterol lowering medication 1.5 2.2 6.5 -1.7 -1.3 0.6 -1.8 1.6 -0.1 2.6 -0.7
Medication: Omeprazole (e.g. Zanprol) 0.7 0.8 2.4 -0.7 -0.9 1.0 -0.8 1.5 0.2 1.0 0.1
Pain experienced in last month 0.6 0.9 3.3 -1.6 -1.8 -1.1 -0.1 -0.0 0.4 0.2 -0.1
Supplements: Calcium 2.1 2.3 5.7 0.1 0.0 1.5 -2.4 1.6 -1.3 2.2 1.1
Basal cell carcinoma (self-reported) 1.1 1.3 3.8 0.8 0.8 1.1 1.9 -0.1 1.5 -1.4 -0.7
Heart attack/myocardial infarction (self-reported) 1.4 1.9 4.5 -1.7 -1.1 -1.4 -1.2 -0.1 -2.1 0.7 -1.5
Deep venous thrombosis (DVT) (self-reported) 0.4 0.5 1.6 0.3 0.5 -0.6 0.3 -0.9 -0.3 -1.3 -1.1
Heart disease (siblings) 0.7 0.8 2.0 -1.1 -0.8 0.5 -0.9 1.2 -1.4 0.5 -0.0
Alcohol drinker status: Previous 1.6 1.8 3.5 1.9 1.9 -1.0 0.7 -1.4 1.2 -1.4 0.6
Pack years of smoking 2.8 4.0 9.5 1.6 2.0 -2.8 1.5 -3.1 -0.2 -2.5 0.2
Impedance of whole body 0.3 1.6 9.2 0.4 -0.0 0.1 0.9 -1.5 -0.3 -3.0 0.1
Leg fat mass (left) 0.9 3.5 7.8 2.6 2.4 0.6 0.8 1.9 -1.2 1.4 2.8
Arm predicted mass (left) 0.2 1.0 4.6 0.6 0.9 -0.2 -1.0 1.1 -0.2 2.1 0.2