Hub : Genes

FBXO32

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0790 0.0300 0.006 -0.001 0.008 0.023 0.012 0.013 0.570 0.036 6.4e-04 0.011 0.00850
2 METSIM Adipose 0.0552 0.0265 0.018 0.007 0.004 0.049 0.009 0.023 0.023 0.085 6.8e-08 0.016 0.00017

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2
Bipolar Disorder (2018) 0.4 0.6 0.8 0.6 -0.9
Bipolar Disorder or Schizophrenia 0.3 0.8 1.2 0.6 -1.1
Depressed Affect (Nagel 2018) 0.0 0.0 0.0 0.1 -0.2
Depression (Nagel 2018) 0.6 0.9 1.7 1.3 0.4
Intelligence (Savage-Jansen 2018) 2.3 7.0 12.8 1.1 3.6
Neuroticism (Nagel 2018) 0.7 1.6 3.1 0.4 -1.8
Schizophrenia (2018) 0.1 0.3 0.5 0.3 -0.7
Schizophrenia vs Biploar Disorder 0.1 0.2 0.3 -0.3 0.5
Worry (Nagel 2018) 1.0 2.1 3.0 1.1 -1.7
Alzheimer’s Disease (in mother) 0.6 0.7 1.2 1.1 0.5
Alzheimer’s Disease (in father) 0.0 0.0 0.0 -0.0 0.1
Alzheimer’s Disease (including proxy) 0.8 1.2 1.7 0.9 1.3
Crohns Disease (2017) 0.1 0.2 0.2 -0.5 0.4
Irritable Bowel Disease (IBD) 0.2 0.4 0.8 -0.1 0.9
Ulcerative Colitis (UC) 0.4 0.7 1.3 -0.3 1.1
Major Depression (MDD) 1.5 1.8 2.9 0.8 1.7
Reaction Time 0.2 0.3 0.4 -0.7 -0.4
Verbal and Numeric Reasoning (VNR) 1.3 3.1 5.8 0.7 2.4
Breast Cancer 6.9 16.5 32.3 0.8 -5.7
Ovarian Cancer 0.3 0.4 0.8 -0.1 -0.9
Prostate Cancer 1.3 1.8 3.6 0.2 -1.9
Age at First Birth 0.0 0.0 0.0 -0.2 -0.2
Bipolar Disorder (2011) 1.1 1.0 1.1 1.0 1.0
Body Mass Index (BMI) (2010) 0.0 0.0 0.1 -0.1 0.3
Coronary Artery Disease (CAD) 0.5 0.6 1.3 -1.1 -0.1
Crohns Disease (2012) 0.2 0.4 0.4 0.6 0.6
Mean Putamen Volume 6.9 7.8 15.5 -3.9 -0.5
Fasting Glucose 0.0 0.0 0.1 -0.3 -0.1
HbA1C 0.4 0.5 0.6 -0.8 0.6
HDL Cholesterol 0.7 1.2 2.2 1.5 -0.3
LDL Cholesterol 0.4 0.7 1.2 -1.1 -0.4
Lupus 0.5 0.8 1.1 -0.7 -1.1
Neuroticism (2016) 0.7 1.0 1.6 1.3 0.6
Primary Biliary Cirrhosis 0.9 1.3 2.5 1.6 0.3
Rheumatoid Arthritis 0.9 1.3 2.5 1.6 0.1
Schizophrenia (2014) 0.2 0.4 0.6 0.7 -0.6
Triglycerides 0.3 0.5 0.8 0.9 0.5
Type 2 Diabetes (T2D) (2012) 0.0 0.1 0.1 -0.3 -0.2
Ulcerative Colitis 0.3 0.4 0.5 0.5 0.7
Blood Eosinophil Count 0.3 2.1 4.2 -0.2 2.1
Blood Platelet Count 0.1 1.3 2.3 -0.6 1.5
Blood Red Count 0.1 0.6 0.9 0.9 -0.6
Blood White Count 0.5 3.4 6.6 2.6 0.3
Heel T-Score 1.2 9.8 12.5 2.7 3.5
BMI 0.7 4.0 5.9 -2.4 -1.4
Height 0.0 0.3 0.5 -0.7 0.2
Waist Hip Ratio (WHR) 0.7 3.2 4.1 -1.5 -2.0
Systolic Blood Pressure 0.7 3.3 4.9 1.3 -2.2
Smoking Status 0.2 0.6 1.1 1.0 0.2
Allergy or Eczema 1.0 2.5 5.1 0.1 2.2
Cardiovascular Disease 0.0 0.1 0.1 -0.3 -0.3
Hypothyroidism (self reported) 0.8 1.8 3.1 -1.8 -0.7
Respiratory disease 0.3 0.7 1.1 0.6 -1.1
Type 2 Diabetes (T2D) (2018) 0.0 0.1 0.1 -0.3 0.1
Lung FEV1/FVC ratio 0.1 0.3 0.5 0.3 0.7
Lung FVC 0.6 2.8 5.6 0.4 2.4
Neuroticism 0.3 0.7 1.3 0.2 -1.1
Chronotype (morning person) 0.7 1.6 2.0 -1.4 1.1
Hair Pigment 0.0 0.0 0.1 -0.3 0.0
Tanning 0.2 2.8 5.2 2.3 0.6
Hand grip strength (left) 0.3 0.9 1.6 1.2 -0.4
Number of treatments/medications taken 0.6 1.1 1.7 -1.3 -0.8
Average weekly spirits intake 0.1 0.2 0.3 -0.5 -0.2
Sensitivity / hurt feelings 1.3 2.2 4.2 0.5 -2.0
Frequency of depressed mood in last 2 weeks 0.6 0.9 1.7 1.3 -0.3
Hearing difficulty/problems: Yes 1.1 1.7 3.3 -0.1 1.8
Relative age of first facial hair 0.4 0.8 1.3 0.5 -1.1
Other serious medical condition/disability diagnosed by doctor 2.3 3.0 3.7 1.9 1.5
Ever used hormone-replacement therapy (HRT) 0.1 0.2 0.3 -0.1 -0.6
Ever had hysterectomy (womb removed) 0.6 0.6 1.2 -0.3 -1.1
Systolic blood pressure, automated reading 0.6 1.9 2.2 1.2 -1.5
Eye problems/disorders: Diabetes related eye disease 0.3 0.3 0.4 -0.6 0.5
Angina 1.7 2.2 4.1 -0.5 -2.0
Medication for hormone replacement therapy 0.1 0.1 0.1 -0.2 -0.4
Vitamin and mineral supplements 1.7 2.3 3.6 -1.0 1.9
Supplements: Zinc 3.8 4.2 6.7 -1.3 -2.6
Medication: Co-codamol 0.6 0.7 1.3 -1.1 0.2
Medication: Metformin 0.1 0.1 0.2 -0.4 -0.1
Diabetes (father) 1.0 1.3 1.6 1.3 1.0
Diabetes (mother) 1.1 1.4 2.7 -0.4 -1.6
Severe depression (siblings) 2.3 2.6 3.2 1.8 1.4
Pack years adult smoking proportion 0.5 0.7 1.4 0.1 -1.2
Impedance of leg (right) 0.1 0.6 1.0 0.5 1.0
Leg fat-free mass (left) 0.1 0.4 0.6 -0.6 -0.7
Trunk fat percentage 0.5 2.0 3.2 -1.8 -1.0
Hand grip strength (right) 0.7 1.8 3.3 1.8 -0.5
Townsend deprivation index at recruitment 0.9 1.3 1.8 -0.9 -1.3
Current tobacco smoking 1.5 2.5 3.5 1.2 -1.9
Average weekly fortified wine intake 0.0 0.0 0.0 0.0 -0.1
Maternal smoking around birth 0.5 0.8 1.5 -1.2 0.3
Fed-up feelings 0.0 0.0 0.0 0.0 -0.2
Frequency of unenthusiasm / disinterest in last 2 weeks 0.5 0.7 0.8 0.9 0.7
Relative age voice broke 1.5 2.2 4.4 2.1 0.2
Taking other prescription medications 1.7 2.6 3.5 -1.9 1.3
Age when periods started (menarche) 1.2 2.9 5.5 0.5 2.4
Bilateral oophorectomy (both ovaries removed) 1.0 1.2 2.0 -1.4 0.6
Heel bone mineral density (BMD) T-score, automated (left) 1.6 3.6 3.6 1.9 1.9
Tinnitus: Yes, but not now, but have in the past 0.5 0.5 0.6 0.7 0.8
Qualifications: CSEs or equivalent 0.7 0.9 1.3 0.7 1.1
Serious illness, injury or assault to yourself 0.1 0.2 0.2 -0.3 0.5
High blood pressure 0.9 2.6 2.9 -1.7 -1.5
Hayfever, allergic rhinitis or eczema 0.6 1.4 2.3 0.7 1.5
Multivitamins +/- minerals 0.2 0.3 0.3 0.6 -0.5
Stomach or abdominal pain in last month 0.4 0.5 0.9 -0.3 -0.9
Supplements: Glucosamine 1.9 2.4 3.5 1.9 -1.2
Diverticular disease/diverticulitis (self-reported) 0.5 0.6 1.2 -0.1 -1.1
Medication: Atenolol 0.3 0.4 0.8 -0.9 -0.2
Medication: Levothyroxine sodium 1.2 2.0 3.7 -1.9 -0.6
Sitting height 0.0 0.0 0.1 0.3 0.1
Chronic bronchitis/emphysema (father) 1.0 1.2 2.0 0.6 -1.4
High blood pressure (mother) 0.2 0.3 0.3 -0.6 -0.5
Body mass index (BMI) 0.3 1.3 1.4 -1.1 -1.2
Impedance of leg (left) 0.1 0.5 1.0 -0.3 1.0
Leg predicted mass (left) 0.1 0.5 0.6 -0.6 -0.8
Trunk fat mass 0.5 2.1 2.9 -1.7 -1.1
Waist circumference 0.5 2.0 3.0 -1.0 -1.7
Number of incorrect matches in round 2.2 3.6 3.7 -1.9 -1.9
Past tobacco smoking 0.0 0.1 0.1 -0.3 0.1
Alcohol usually taken with meals 0.3 0.5 0.7 0.7 0.8
Nervous feelings 1.0 1.9 3.3 0.7 -1.8
Frequency of tenseness / restlessness in last 2 weeks 1.5 2.3 4.5 2.1 -0.0
Hearing difficulty/problems with background noise 0.1 0.1 0.2 -0.4 0.3
Hair/balding pattern: Pattern 2 0.7 0.9 1.7 -1.3 -0.1
Had menopause 0.8 1.1 1.9 0.4 -1.4
Had other major operations 1.7 2.1 3.5 -0.8 1.9
Forced vital capacity (FVC) 1.3 4.9 9.8 -0.2 3.1
Heel bone mineral density (BMD) T-score, automated (right) 1.0 2.3 4.5 0.2 2.1
Ever unenthusiastic/disinterested for a whole week 0.3 0.4 0.7 -0.2 0.8
Qualifications: None of the above 0.1 0.2 0.4 -0.7 -0.0
Financial difficulties in last 2 years 0.1 0.2 0.2 0.5 0.4
Mouth/teeth dental problems 0.2 0.3 0.6 0.1 0.8
Heart attack 1.6 2.0 4.1 -0.1 -2.0
Allergy 0.0 0.1 0.1 0.1 0.3
Pain all over the body in last month 1.1 1.2 2.4 -0.3 1.5
Diabetes (self-reported) 0.5 0.8 1.1 -1.0 -0.8
Hayfever/allergic rhinitis (self-reported) 4.7 6.2 6.4 -2.4 2.5
Medication: Ramipril 0.8 1.1 2.1 0.1 -1.4
Medication: Simvastatin 0.8 1.2 2.3 -0.3 -1.5
Fluid intelligence score 0.8 1.6 3.1 -0.2 1.8
Illnesses of siblings 0.3 0.5 1.0 -1.0 -0.1
Neuroticism score 0.3 0.7 0.9 1.0 -0.7
Weight 0.3 1.3 1.4 -1.2 -1.1
Impedance of arm (right) 0.5 2.5 5.0 -2.2 0.1
Arm fat percentage (right) 0.6 2.5 3.5 -1.9 -1.2
Trunk fat-free mass 0.0 0.1 0.1 0.4 -0.0
Hip circumference 0.1 0.2 0.4 0.3 -0.6
Time employed in main current job 1.4 1.7 3.3 -0.3 -1.8
Alcohol intake versus 10 years previously 0.2 0.3 0.3 -0.6 0.5
Father’s age at death 0.3 0.3 0.7 0.2 0.8
Worrier / anxious feelings 0.1 0.2 0.3 -0.5 0.4
Frequency of tiredness / lethargy in last 2 weeks 0.9 1.5 2.8 1.7 0.4
Falls in the last year 0.1 0.2 0.3 -0.5 -0.1
Hair/balding pattern: Pattern 3 0.2 0.3 0.5 0.2 -0.7
Number of live births 1.9 2.6 3.9 1.2 -2.0
Forced expiratory volume in 1-second (FEV1) 1.6 5.2 10.5 0.0 3.2
Pulse rate 1.0 1.8 2.5 -1.6 -1.0
Happiness 0.7 0.8 1.4 -1.2 0.5
Noisy workplace 1.8 2.2 2.8 1.7 1.3
Qualifications: A levels/AS levels or equivalent 0.3 0.6 0.9 1.0 -0.4
Serious illness, injury or assault of a close relative in last 2 years 1.0 1.2 2.3 -0.0 1.5
Mouth/teeth dental problems: Dentures 0.1 0.2 0.3 -0.4 0.6
Asthma 0.2 0.4 0.5 0.7 -0.6
Medication: Ibuprofen (e.g. Nurofen) 0.5 0.6 1.2 -0.3 1.1
Medication: Cholesterol lowering 0.8 1.2 2.4 -0.0 -1.5
Depression (self-reported) 0.7 0.8 1.3 0.5 1.2
Medication: Lansoprazole 2.3 2.6 4.1 -1.0 -2.0
Prospective memory result 1.0 1.3 2.1 0.7 -1.5
Lung cancer (father) 0.0 0.0 0.1 -0.2 -0.2
Illnesses of mother 0.9 1.1 1.2 1.1 1.0
Forced expiratory volume in 1-second (FEV1), Best measure 1.7 5.4 9.5 1.2 3.1
Pulse wave Arterial Stiffness index 2.4 2.8 3.6 -1.9 -1.4
Impedance of arm (left) 0.3 1.5 2.9 -1.7 -0.2
Arm fat mass (right) 0.4 1.5 1.8 -1.3 -1.1
Trunk predicted mass 0.0 0.1 0.2 0.5 -0.0
Standing height 0.0 0.1 0.2 -0.5 -0.2
Length of working week for main job 0.1 0.1 0.1 0.3 0.3
Exposure to tobacco smoke at home 0.7 0.8 1.6 -0.0 -1.3
Breastfed as a baby 0.1 0.2 0.3 -0.6 -0.0
Tense / ‘highly strung’ 2.9 4.8 4.8 2.2 -2.2
Seen doctor (GP) for nerves, anxiety, tension or depression 0.9 1.4 1.7 1.1 1.3
Hair/balding pattern: Pattern 4 0.6 1.4 2.1 1.4 0.8
Birth weight of first child 0.6 1.0 2.1 -0.1 1.4
Peak expiratory flow (PEF) 1.8 4.1 8.1 -0.4 2.9
Pulse wave reflection index 0.3 0.4 0.7 0.8 -0.2
Ever highly irritable/argumentative for 2 days 0.8 0.9 1.8 -0.3 1.3
Loud music exposure frequency 0.0 0.0 0.0 0.0 0.1
Qualifications: O levels/GCSEs or equivalent 0.1 0.1 0.2 0.5 -0.2
Mouth/teeth dental problems: Bleeding gums 0.0 0.0 0.0 -0.1 -0.2
Blood clot in the leg (DVT) 2.9 3.7 4.2 -2.0 -1.8
Medication: Paracetamol 0.5 0.8 1.5 -0.1 1.2
Headache pain in last month 1.4 2.4 4.7 -0.2 2.2
Medication for cholesterol, blood pressure or diabetes 0.5 0.9 1.7 0.4 1.3
Glaucoma (self-reported) 1.7 2.0 2.6 1.2 1.6
Gout (self-reported) 0.5 0.7 0.8 -0.7 -0.9
Hypothyroidism/myxoedema (self-reported) 0.8 1.5 3.0 -1.7 -0.2
Medication: Amlodipine 0.1 0.1 0.2 -0.0 0.4
Medication: Ventolin 100micrograms inhaler 1.6 2.1 2.6 1.2 1.6
Birth weight 0.3 0.7 1.0 -1.0 0.7
Chronic bronchitis/emphysema (mother) 1.2 1.4 2.5 -1.6 -0.6
High blood pressure (siblings) 0.3 0.5 0.5 0.7 0.6
Forced vital capacity (FVC), Best measure 1.4 5.3 9.8 0.9 3.1
Body fat percentage 0.5 1.8 2.6 -1.6 -1.0
Leg fat percentage (right) 0.3 1.3 1.5 -1.0 -1.2
Arm fat-free mass (right) 0.1 0.4 0.7 0.8 -0.3
Exposure to tobacco smoke outside home 1.3 1.7 2.2 -1.5 1.1
Comparative body size at age 10 0.7 1.9 2.9 -0.9 -1.7
Number of full brothers 2.1 2.7 4.3 -1.0 -2.1
Worry too long after embarrassment 1.3 2.2 4.0 0.7 -2.0
Seen a psychiatrist for nerves, anxiety, tension or depression 0.3 0.4 0.4 0.6 0.6
Wheeze or whistling in the chest in last year 0.5 0.8 1.7 1.3 -0.1
Number of children fathered 0.3 0.4 0.7 0.8 -0.1
Reason for reducing amount of alcohol drunk: Health precaution 1.5 1.7 3.3 -0.4 -1.8
Age at first live birth 0.2 0.3 0.6 0.0 0.8
Pulse wave peak to peak time 1.9 2.3 2.9 1.7 1.3
Health satisfaction 0.3 0.4 0.6 0.3 -0.8
Shortness of breath walking on level ground 0.4 0.5 0.5 -0.7 0.7
Qualifications: College or University degree 0.1 0.2 0.2 0.4 -0.4
Eye problems/disorders: None of the above 2.7 3.1 5.5 0.9 -2.4
Mouth/teeth dental problems: Loose teeth 0.6 0.7 1.1 -0.5 -1.1
Emphysema/chronic bronchitis 4.2 4.8 7.9 -1.3 -2.8
Medication for pain relief, constipation, heartburn 0.2 0.3 0.4 -0.4 -0.7
Neck or shoulder pain in last month 0.3 0.4 0.5 0.6 0.7
Medication: Blood pressure 0.3 0.6 0.7 -0.6 -0.9
Angina (self-reported) 2.2 2.8 5.4 -0.5 -2.3
Migraine (self-reported) 2.2 2.7 5.3 -0.3 2.3
Medication: Ibuprofen 1.1 1.3 1.4 -1.1 1.2
Medication: Allopurinol 1.1 1.4 1.6 -1.2 -1.2
Medication: Omeprazole 1.7 2.1 3.7 1.9 0.6
Medication: Seretide 50 evohaler 0.1 0.1 0.2 0.0 -0.5
Mean time to correctly identify matches 0.7 1.4 1.6 -1.1 -1.3
Heart disease (mother) 0.6 0.8 1.5 -0.1 -1.2
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.2 0.3 0.4 -0.4 0.6
Whole body fat mass 0.4 1.5 1.8 -1.4 -1.1
Leg fat mass (right) 0.3 1.1 1.2 -1.0 -1.1
Arm predicted mass (right) 0.1 0.4 0.6 0.8 -0.4
Pulse rate, automated reading 0.6 1.8 3.6 -1.9 0.1
Alcohol intake frequency. 0.6 1.4 2.7 -0.4 1.6
Comparative height size at age 10 0.0 0.2 0.5 0.7 -0.1
Number of full sisters 1.9 2.3 2.5 -1.4 -1.6
Suffer from ‘nerves’ 0.4 0.7 1.4 -0.2 -1.2
Overall health rating 0.1 0.2 0.3 0.6 0.0
Chest pain or discomfort 0.4 0.6 1.2 1.1 -0.2
Had major operations 0.7 0.8 1.3 -0.4 1.2
Age at last live birth 1.0 1.5 2.4 0.8 1.5
Family relationship satisfaction 0.4 0.4 0.8 -0.9 -0.3
Leg pain on walking 0.2 0.2 0.3 -0.6 0.2
Qualifications: NVQ or HND or HNC or equivalent 0.1 0.1 0.1 0.3 -0.2
Commuting to job workplace: Car/motor vehicle 2.3 2.6 5.1 2.3 0.2
Illness, injury, bereavement, stress in last 2 years 0.8 1.0 1.5 -1.2 -0.7
Medication: Aspirin 0.6 0.7 1.1 1.1 -0.6
Supplements: Vitamin C 2.6 3.1 6.1 0.1 -2.5
Knee pain experienced in last month 0.5 0.8 1.4 -0.4 -1.2
Hypertension (Self-reported) 0.9 2.4 2.5 -1.5 -1.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.0 0.1 0.1 -0.3 -0.2
Illnesses of father: Heart disease 0.4 0.6 1.0 -0.4 -1.0
Illnesses of siblings: Diabetes 0.6 0.7 1.1 0.5 1.1
Smoking status: Previous 0.2 0.3 0.4 -0.6 0.5
Forced expiratory volume in 1-second (FEV1), predicted 1.5 3.1 5.5 0.8 2.3
Whole body fat-free mass 0.0 0.1 0.1 -0.1 -0.4
Leg fat-free mass (right) 0.1 0.6 0.7 -0.8 -0.7
Arm fat percentage (left) 0.6 2.5 2.7 -1.5 -1.7
Average weekly red wine intake 0.8 1.2 1.2 1.1 -1.1
Handedness (chirality/laterality): Left-handed 0.7 0.8 1.4 -1.2 -0.4
Mood swings 0.2 0.3 0.5 0.4 -0.7
Loneliness, isolation 0.4 0.6 1.2 1.1 -0.2
Long-standing illness, disability or infirmity 0.1 0.2 0.2 0.4 0.4
Ever had bowel cancer screening 0.9 1.0 1.0 -1.0 -1.0
Diabetes diagnosed by doctor 0.0 0.1 0.2 -0.0 -0.4
Ever had stillbirth, spontaneous miscarriage or termination 0.9 1.0 1.6 -1.3 0.6
Friendships satisfaction 0.3 0.4 0.6 0.5 0.8
Qualifications: nursing, teaching 0.2 0.3 0.5 -0.7 0.1
Commuting to job workplace: Walk 3.0 3.3 4.8 -2.2 -1.3
Eye problems/disorders: Cataract 1.4 1.6 1.8 1.3 1.2
Mouth/teeth dental problems: Mouth ulcers 0.9 1.5 1.6 -1.2 -1.3
Medication for cholesterol 1.1 1.7 2.9 0.8 1.7
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.2 0.2 0.4 0.6 0.3
Back pain experienced in last month 0.3 0.4 0.8 0.9 0.1
Mineral and other dietary supplements 3.5 4.7 5.3 -2.0 2.3
Breast cancer (self-reported) 2.0 2.4 4.6 -0.5 2.2
Asthma (self-reported) 0.1 0.3 0.4 0.3 -0.6
Osteoporosis (self-reported) 0.5 0.7 0.9 -0.7 -0.9
Osteoarthritis (self-reported) 0.4 0.5 0.8 0.9 0.5
Medication: Aspirin 0.5 0.7 0.9 0.7 -1.0
Medication: Gliclazide 0.7 0.8 1.5 -0.4 1.2
Illnesses of father: None of the above (group 1) 0.5 0.6 1.0 0.3 1.0
Smoking status: Current 1.6 2.5 3.7 1.1 -1.9
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.9 3.9 7.8 -0.1 2.8
Whole body water mass 0.0 0.1 0.2 0.1 -0.4
Leg predicted mass (right) 0.1 0.6 0.7 -0.8 -0.7
Arm fat mass (left) 0.5 1.9 1.9 -1.4 -1.4
Number of self-reported non-cancer illnesses 0.4 0.7 1.5 -1.2 0.1
Average weekly champagne plus white wine intake 0.2 0.3 0.4 -0.4 0.7
Miserableness 0.0 0.0 0.0 -0.0 -0.0
Guilty feelings 0.1 0.1 0.1 0.3 -0.3
Wears glasses or contact lenses 0.0 0.0 0.1 0.1 0.2
Ever taken oral contraceptive pill 0.3 0.3 0.4 0.6 0.5
Hearing aid user 0.3 0.4 0.4 -0.7 -0.6
Mother’s age at death 2.3 2.9 3.6 -1.9 -1.5
Financial situation satisfaction 0.1 0.1 0.2 0.5 -0.1
Tinnitus: Yes, now most or all of the time 0.4 0.5 0.6 0.8 0.7
Commuting to job workplace: Public transport 1.3 1.5 3.0 -1.7 0.1
Eye problems/disorders: Glaucoma 2.7 3.2 4.9 1.3 2.2
Medication: Blood pressure 1.9 3.6 5.2 -1.4 -2.3
Pain type(s) experienced in last month: Hip pain 0.7 0.9 1.3 0.7 -1.1
Supplements: Fish oil (including cod liver oil) 2.6 3.4 3.9 2.0 -1.7
High cholesterol (Self-reported) 0.9 1.6 2.0 -1.1 -1.4
Medication: Bendroflumethiazide 3.0 4.5 6.3 -1.6 -2.5
Medication: Paracetamol 0.2 0.3 0.6 0.1 0.8
Medication: Lisinopril 0.0 0.0 0.1 -0.0 0.3
Medication: Atorvastatin 0.8 1.0 1.4 1.2 -0.8
Illnesses of father: High blood pressure 0.2 0.2 0.5 -0.1 -0.7
Alcohol drinker status: Never 0.4 0.5 0.9 -0.1 1.0
Ever smoked 0.7 1.2 2.4 1.5 -0.3
Basal metabolic rate 0.0 0.2 0.2 -0.3 -0.5
Leg fat percentage (left) 0.6 2.0 2.6 -1.6 -1.2
Arm fat-free mass (left) 0.0 0.0 0.1 0.1 -0.3
Number of operations (self-reported) 1.2 1.7 3.0 -1.7 0.6
Average weekly beer plus cider intake 0.5 0.7 1.1 -0.6 1.0
Irritability 0.6 1.0 1.1 1.1 -0.9
Risk taking 0.2 0.3 0.4 0.6 0.5
Ever had prostate specific antigen (PSA) test 1.5 1.7 3.3 -0.4 -1.8
Fractured/broken bones in last 5 years 0.1 0.1 0.1 -0.3 0.3
Age started oral contraceptive pill 0.3 0.4 0.5 0.7 -0.5
Diastolic blood pressure, automated reading 0.4 1.1 2.2 -0.2 -1.5
Ever depressed for a whole week 0.1 0.1 0.2 0.1 0.5
Unable to work because of sickness or disability 0.3 0.4 0.8 -0.1 0.9
Commuting to job workplace: Cycle 0.1 0.1 0.2 -0.4 -0.2
Myopia 2.3 3.4 3.9 2.0 -1.7
Vascular/heart problems diagnosed by doctor 1.2 3.2 3.9 1.6 2.0
Cholesterol lowering medication 0.3 0.4 0.6 0.6 -0.7
Medication: Omeprazole (e.g. Zanprol) 0.7 0.9 1.7 1.3 0.4
Pain experienced in last month 0.0 0.0 0.0 -0.1 -0.0
Supplements: Calcium 6.6 7.3 13.3 3.6 -1.1
Basal cell carcinoma (self-reported) 0.4 0.4 0.8 0.9 0.2
Heart attack/myocardial infarction (self-reported) 1.4 1.9 3.7 -0.1 -1.9
Deep venous thrombosis (DVT) (self-reported) 2.9 3.8 4.4 -2.1 -1.8
Heart disease (siblings) 1.0 1.2 2.0 -0.6 -1.4
Alcohol drinker status: Previous 1.5 1.7 2.1 -1.4 1.2
Pack years of smoking 0.5 0.8 1.5 -0.2 -1.2
Impedance of whole body 0.2 0.8 1.3 -1.1 0.6
Leg fat mass (left) 0.4 1.5 1.9 -1.4 -1.1
Arm predicted mass (left) 0.0 0.1 0.1 0.3 -0.3