Hub : Genes

FGD5-AS1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Adipose Subcutaneous 0.1300 0.0430 9.5e-04 0.019 NA 0.029 NA 0.037 1.0e-02 NA 1.9e-03 NA 5.2e-04
2 GTEx Adipose Visceral Omentum 0.1550 0.0580 3.7e-03 0.013 NA 0.055 NA 0.007 6.7e-02 NA 8.1e-04 NA 1.4e-01
3 GTEx Brain Cerebellum 0.2500 0.0820 2.3e-03 0.166 NA 0.110 NA 0.117 1.2e-05 NA 3.9e-04 NA 2.5e-04
4 GTEx Esophagus Gastroesophageal Junction 0.2490 0.0900 7.2e-03 -0.008 NA -0.007 NA -0.008 9.1e-01 NA 7.3e-01 NA 9.2e-01
5 GTEx Esophagus Mucosa 0.2310 0.0560 1.5e-06 0.002 NA 0.099 NA 0.104 2.3e-01 NA 3.9e-07 NA 2.0e-07
6 GTEx Nerve Tibial 0.0922 0.0360 3.9e-03 0.054 NA 0.030 NA 0.038 1.1e-04 NA 3.4e-03 NA 1.0e-03
7 GTEx Pituitary 0.3280 0.0950 6.9e-04 0.193 NA 0.155 NA 0.180 1.4e-05 NA 1.1e-04 NA 2.8e-05
8 GTEx Thyroid 0.1540 0.0400 5.7e-06 0.100 NA 0.078 NA 0.098 4.4e-08 NA 1.5e-06 NA 6.3e-08
9 ROSMAP Brain Pre-frontal Cortex 0.1522 0.0352 6.7e-07 0.049 0.079 0.067 0.108 0.063 6.1e-07 2.2e-10 5.9e-09 1e-13 1.4e-08

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bipolar Disorder (2018) 0.4 0.7 2.0 0.9 -1.3 0.1 0.0 0.4 -0.6 0.6 0.8 1.4
Bipolar Disorder or Schizophrenia 0.2 0.6 1.7 1.2 0.2 -0.6 0.0 0.8 -1.1 -0.4 0.2 1.3
Depressed Affect (Nagel 2018) 0.5 1.0 2.8 -1.1 0.1 -1.2 0.0 0.2 -1.3 -0.9 -1.7 -0.9
Depression (Nagel 2018) 0.3 0.4 1.5 -0.9 0.4 0.5 0.0 -1.2 0.3 0.1 -0.4 -0.9
Intelligence (Savage-Jansen 2018) 0.2 0.5 1.4 1.2 -0.3 -0.4 0.0 1.1 -0.5 -0.2 0.8 0.9
Neuroticism (Nagel 2018) 0.1 0.2 0.6 -0.8 -0.6 -0.3 0.0 -0.3 -0.5 -0.3 -0.5 -0.3
Schizophrenia (2018) 0.3 0.6 1.9 0.7 1.4 -0.9 0.0 0.6 -0.8 -1.0 -0.4 0.5
Schizophrenia vs Biploar Disorder 1.0 1.3 3.6 0.8 0.6 1.1 0.0 0.5 1.6 1.2 1.9 1.1
Worry (Nagel 2018) 0.1 0.2 0.5 -0.6 -0.5 0.0 0.0 -0.4 -0.2 -0.5 -0.4 -0.7
Alzheimer’s Disease (in mother) 0.8 0.9 2.6 0.9 1.5 0.3 0.0 0.5 -0.3 1.6 0.7 1.2
Alzheimer’s Disease (in father) 0.5 0.5 1.8 1.4 -0.4 -0.9 0.0 -0.4 -0.8 -0.0 -0.8 0.3
Alzheimer’s Disease (including proxy) 0.4 0.6 1.8 0.7 1.2 -0.5 0.0 -0.3 -0.7 1.4 0.6 0.9
Crohns Disease (2017) 0.4 0.8 1.9 -0.7 0.4 -1.0 0.0 -0.8 -1.0 -1.2 -1.4 -0.9
Irritable Bowel Disease (IBD) 0.5 1.2 3.4 -1.0 -0.2 -0.1 0.0 -0.9 -0.4 -1.5 -1.6 -1.8
Ulcerative Colitis (UC) 0.4 0.7 2.8 -0.6 -0.7 1.1 0.0 -0.4 0.7 -0.7 -0.7 -1.7
Major Depression (MDD) 0.6 0.7 1.4 0.5 -1.2 -0.1 0.0 1.1 -0.7 1.2 0.6 1.0
Reaction Time 0.8 1.5 4.3 1.1 -0.2 -1.4 0.0 2.0 -2.1 -0.5 -1.1 0.9
Verbal and Numeric Reasoning (VNR) 0.4 0.9 3.2 1.8 0.4 -0.3 0.0 1.3 -0.3 0.1 0.9 1.3
Breast Cancer 0.2 0.4 1.4 -0.1 -0.5 -1.2 0.0 -0.7 -0.8 -0.3 -0.6 0.2
Ovarian Cancer 0.4 0.6 1.6 -0.6 -0.8 -1.3 0.0 -1.0 -0.6 -1.1 -0.1 0.2
Prostate Cancer 0.8 1.1 2.9 1.4 1.7 0.7 0.0 0.1 0.5 1.2 0.8 1.4
Age at First Birth 0.3 0.5 1.9 -1.4 -0.2 0.5 0.0 -1.3 0.5 0.4 0.1 -0.2
Bipolar Disorder (2011) 1.9 1.9 5.2 -0.8 0.5 -2.0 0.0 1.2 -2.3 -1.1 -2.0 -0.1
Body Mass Index (BMI) (2010) 0.7 1.0 2.7 -0.5 -0.6 -1.6 0.0 0.1 -1.5 -1.2 -1.3 -0.5
Coronary Artery Disease (CAD) 1.0 1.2 6.7 -0.8 2.6 0.0 0.0 1.2 -0.6 -0.3 -0.9 -0.6
Crohns Disease (2012) 0.7 1.1 3.1 -1.2 0.5 -0.8 0.0 -1.8 -0.4 -1.4 -1.2 -1.0
Mean Putamen Volume 1.0 1.1 3.6 -0.1 -0.1 1.4 0.0 0.3 1.6 1.9 1.4 0.3
Fasting Glucose 1.5 1.8 4.2 1.2 2.0 -2.0 0.0 1.5 -1.6 -0.3 -0.3 1.2
HbA1C 1.6 1.8 5.0 -0.2 0.8 -1.5 0.0 1.0 -1.8 -1.9 -2.2 -0.6
HDL Cholesterol 0.3 0.5 1.8 -1.4 -0.4 0.4 0.0 -0.7 0.2 -0.3 -0.6 -1.1
LDL Cholesterol 0.5 0.8 2.3 0.6 -0.3 1.1 0.0 -0.4 1.0 1.5 1.1 0.7
Lupus 1.3 2.0 4.8 1.7 0.6 1.0 0.0 1.1 0.3 2.1 1.8 2.2
Neuroticism (2016) 0.7 0.9 2.7 -1.2 -0.0 -0.9 0.0 -0.7 -0.7 -1.1 -1.6 -1.2
Primary Biliary Cirrhosis 1.1 1.5 5.8 0.6 1.7 -1.7 0.0 2.4 -1.1 0.1 -0.3 0.6
Rheumatoid Arthritis 0.6 0.8 2.3 -0.5 -1.0 -1.1 0.0 1.0 -1.5 -0.5 -1.0 0.2
Schizophrenia (2014) 0.5 1.1 2.9 1.4 0.9 -0.6 0.0 1.7 -0.8 -0.2 0.3 1.6
Triglycerides 0.8 1.4 3.6 1.9 1.6 0.1 0.0 1.2 -0.7 1.1 0.3 1.7
Type 2 Diabetes (T2D) (2012) 1.8 2.0 6.6 -0.9 1.2 -2.6 0.0 0.8 -2.0 -1.8 -1.3 0.0
Ulcerative Colitis 0.2 0.3 1.1 0.0 -0.7 0.7 0.0 -0.6 0.4 -0.2 -0.6 -1.0
Blood Eosinophil Count 0.2 1.6 4.1 2.0 0.6 1.1 0.0 0.4 1.3 1.9 1.3 1.2
Blood Platelet Count 0.5 5.3 14.1 -1.8 -3.2 2.1 0.0 -3.8 3.0 0.3 0.9 -2.4
Blood Red Count 0.3 2.6 8.1 -0.4 2.1 -0.2 0.0 1.6 -0.9 -1.6 -2.9 -2.2
Blood White Count 0.3 1.9 6.7 -0.2 1.2 1.8 0.0 -2.0 2.6 0.6 -0.3 -1.2
Heel T-Score 0.4 2.8 10.0 -1.1 -3.2 0.6 0.0 -2.8 0.7 -0.5 -0.9 -2.0
BMI 0.4 2.2 9.0 0.9 -0.1 -1.7 0.0 3.0 -2.0 -0.3 -0.8 1.5
Height 0.7 14.2 31.8 2.5 3.9 -5.3 0.0 5.6 -5.6 -1.7 -1.5 3.1
Waist Hip Ratio (WHR) 0.2 0.8 2.8 -1.7 0.2 1.4 0.0 0.6 1.2 0.0 0.6 -0.8
Systolic Blood Pressure 0.5 2.4 8.1 -1.4 2.9 0.1 0.0 2.6 0.4 -0.9 -1.2 -1.3
Smoking Status 0.1 0.1 0.8 0.2 -0.1 0.3 0.0 0.3 0.2 0.9 -0.2 -0.0
Allergy or Eczema 0.4 0.9 3.7 -0.1 -0.2 -1.6 0.0 -0.7 -1.9 -0.6 -1.0 0.7
Cardiovascular Disease 0.4 1.3 4.8 -0.4 1.2 -0.7 0.0 2.2 -0.1 -1.3 -1.2 -1.2
Hypothyroidism (self reported) 0.1 0.2 0.6 0.4 0.8 -0.3 0.0 0.3 -0.6 0.1 -0.6 0.4
Respiratory disease 0.1 0.3 1.4 -0.2 0.2 -0.5 0.0 1.2 -0.0 0.9 -0.0 0.3
Type 2 Diabetes (T2D) (2018) 0.4 0.8 3.1 1.3 1.8 0.1 0.0 1.3 0.1 0.2 0.5 0.9
Lung FEV1/FVC ratio 0.2 1.0 4.7 -0.8 -2.2 -0.4 0.0 -0.7 -0.3 -1.2 -0.4 -1.0
Lung FVC 0.2 1.0 2.0 0.7 -0.6 0.9 0.0 -1.2 1.1 1.1 1.4 1.0
Neuroticism 0.1 0.3 1.0 -0.5 -0.4 -0.4 0.0 -1.0 -0.2 -0.4 -0.6 -0.5
Chronotype (morning person) 0.8 1.9 4.8 -1.9 -0.3 -0.5 0.0 -1.9 -0.0 -1.8 -1.4 -2.2
Hair Pigment 0.0 0.2 0.7 0.8 0.8 -0.4 0.0 0.2 -0.4 0.3 0.1 0.1
Tanning 0.2 1.9 6.2 -0.1 0.7 -2.3 0.0 0.3 -2.5 -1.2 -2.0 -0.4
Hand grip strength (left) 0.5 1.3 3.5 0.7 1.9 -0.8 0.0 1.5 0.4 0.7 1.3 1.4
Number of treatments/medications taken 0.4 0.8 5.5 0.8 0.2 0.2 0.0 2.4 0.3 0.7 0.3 0.2
Average weekly spirits intake 0.7 0.9 1.9 -1.3 0.5 -1.2 0.0 0.4 -1.3 -0.8 -1.4 -0.4
Sensitivity / hurt feelings 0.1 0.1 0.9 0.2 0.1 -0.4 0.0 -0.1 -1.0 -0.3 -0.4 0.2
Frequency of depressed mood in last 2 weeks 0.9 1.2 3.5 -1.9 -0.2 -1.1 0.0 -0.6 -0.5 -1.3 -1.5 -1.3
Hearing difficulty/problems: Yes 1.6 2.5 6.0 0.8 -0.5 2.5 0.0 0.4 2.2 2.1 2.4 0.5
Relative age of first facial hair 0.4 0.8 3.8 0.9 -0.2 -0.6 0.0 0.3 -1.9 0.7 -0.8 1.2
Other serious medical condition/disability diagnosed by doctor 2.4 3.1 9.3 3.1 1.3 -0.5 0.0 2.1 -1.2 1.7 0.2 2.8
Ever used hormone-replacement therapy (HRT) 0.4 0.5 1.4 -1.2 -0.9 0.3 0.0 -0.9 0.4 0.5 0.4 -0.5
Ever had hysterectomy (womb removed) 0.3 0.3 1.6 -0.0 -1.2 0.5 0.0 -0.1 0.4 0.9 0.0 -0.3
Systolic blood pressure, automated reading 0.3 1.0 4.6 -0.9 1.7 0.5 0.0 2.2 0.4 -0.3 -0.3 -0.4
Eye problems/disorders: Diabetes related eye disease 0.4 0.5 1.3 0.1 -0.6 -0.8 0.0 0.0 -1.1 -0.4 -1.1 -0.6
Angina 0.5 0.7 2.6 -1.1 0.4 1.0 0.0 -0.5 0.7 0.2 -0.6 -1.6
Medication for hormone replacement therapy 3.0 3.4 9.5 -1.7 -0.9 -1.3 0.0 -1.4 -1.0 -2.4 -3.1 -2.7
Vitamin and mineral supplements 0.9 1.2 2.6 -1.6 -1.0 -1.3 0.0 -0.2 -0.8 -1.6 -1.2 -1.0
Supplements: Zinc 0.4 0.5 1.9 -0.6 0.5 0.0 0.0 -1.4 0.8 -0.6 0.3 -0.7
Medication: Co-codamol 0.8 0.9 1.9 1.1 0.9 0.2 0.0 1.1 0.3 1.2 1.1 1.4
Medication: Metformin 0.1 0.2 1.0 0.2 -0.0 -0.5 0.0 0.1 -0.3 -1.0 -0.3 -0.4
Diabetes (father) 0.6 0.8 2.8 -0.5 -0.5 -0.2 0.0 -0.8 -0.8 -1.7 -1.1 -1.0
Diabetes (mother) 0.4 0.5 1.8 0.8 0.7 -0.3 0.0 -0.3 0.1 0.7 0.8 1.3
Severe depression (siblings) 0.7 0.8 4.1 -0.7 -2.0 -0.0 0.0 -1.2 -0.1 -0.9 -0.1 -0.3
Pack years adult smoking proportion 1.4 2.1 6.9 -2.1 -0.0 -1.6 0.0 0.1 -1.4 -1.5 -2.6 -1.0
Impedance of leg (right) 0.7 3.2 8.7 -0.6 -1.1 3.0 0.0 -2.5 2.7 1.2 1.0 -1.6
Leg fat-free mass (left) 1.7 9.1 25.5 2.4 2.8 -3.9 0.0 5.0 -4.0 -1.0 -0.8 3.1
Trunk fat percentage 0.2 1.0 5.4 -0.2 -1.2 -0.7 0.0 2.3 -0.7 -0.5 -0.7 -0.1
Hand grip strength (right) 0.6 1.6 4.2 0.9 2.0 -0.1 0.0 1.0 0.9 1.5 1.7 1.4
Townsend deprivation index at recruitment 1.2 1.6 5.8 0.1 -0.4 -2.4 0.0 1.4 -2.1 0.1 -1.2 1.0
Current tobacco smoking 0.7 1.1 3.8 0.8 0.7 -1.2 0.0 -0.5 -1.4 -1.0 -2.0 -0.4
Average weekly fortified wine intake 1.9 2.3 7.4 -2.7 -1.6 -0.6 0.0 -1.9 0.3 -1.8 -0.7 -1.6
Maternal smoking around birth 0.1 0.2 0.9 1.0 0.9 -0.2 0.0 -0.2 0.1 -0.3 -0.1 0.1
Fed-up feelings 0.4 0.7 2.1 -0.6 -1.3 -0.6 0.0 -1.4 -0.1 -0.8 -0.5 -0.8
Frequency of unenthusiasm / disinterest in last 2 weeks 0.2 0.2 0.7 -0.0 0.0 0.8 0.0 -0.6 0.7 0.1 0.1 -0.4
Relative age voice broke 0.9 1.4 4.1 0.4 -1.3 -2.0 0.0 0.5 -1.9 -0.1 -1.5 0.5
Taking other prescription medications 0.5 0.8 2.7 -0.1 -0.3 -1.2 0.0 1.6 -1.2 -0.0 -1.0 -0.1
Age when periods started (menarche) 0.1 0.2 0.8 0.9 0.1 -0.2 0.0 0.5 0.1 0.0 0.3 0.7
Bilateral oophorectomy (both ovaries removed) 0.2 0.2 0.6 0.0 -0.8 -0.2 0.0 -0.1 -0.8 -0.2 -0.7 -0.0
Heel bone mineral density (BMD) T-score, automated (left) 0.1 0.2 0.7 0.3 -0.3 -0.1 0.0 -0.8 -0.0 -0.6 -0.4 -0.1
Tinnitus: Yes, but not now, but have in the past 1.4 1.5 5.6 0.4 -1.2 2.4 0.0 -0.9 1.7 1.3 1.0 -0.3
Qualifications: CSEs or equivalent 0.1 0.2 0.7 0.1 -0.0 0.8 0.0 -0.2 0.8 0.4 0.4 -0.2
Serious illness, injury or assault to yourself 0.4 0.5 3.4 -0.3 -0.1 -0.2 0.0 1.8 -0.7 0.3 -0.5 0.1
High blood pressure 0.4 1.1 8.2 0.2 0.6 -0.2 0.0 2.9 0.0 -0.6 -0.8 -0.6
Hayfever, allergic rhinitis or eczema 0.6 1.2 4.3 -0.3 -0.8 -2.0 0.0 0.3 -2.1 -0.5 -1.1 0.6
Multivitamins +/- minerals 0.9 1.2 4.1 1.2 2.0 0.1 0.0 0.7 0.1 1.5 0.9 1.2
Stomach or abdominal pain in last month 0.2 0.2 0.6 -0.3 0.5 -0.1 0.0 0.8 -0.6 0.6 -0.6 0.3
Supplements: Glucosamine 0.4 0.5 1.7 0.2 0.7 -0.3 0.0 0.9 -0.3 1.3 0.6 1.0
Diverticular disease/diverticulitis (self-reported) 0.2 0.2 0.7 0.8 0.8 0.3 0.0 0.5 0.0 0.5 -0.2 0.1
Medication: Atenolol 2.7 3.4 15.9 -0.1 4.0 -1.6 0.0 2.7 -1.8 -0.5 -1.4 -0.2
Medication: Levothyroxine sodium 0.2 0.3 1.1 -0.3 0.8 0.1 0.0 0.3 -0.5 0.1 -1.1 -0.4
Sitting height 1.4 9.6 23.4 2.3 4.8 -4.0 0.0 4.4 -3.7 -0.8 -0.5 2.8
Chronic bronchitis/emphysema (father) 0.2 0.2 1.5 0.4 1.2 -0.1 0.0 -0.1 0.4 0.5 0.2 0.2
High blood pressure (mother) 2.3 3.2 8.1 -1.2 0.2 -2.8 0.0 1.9 -2.6 -1.5 -2.4 -0.4
Body mass index (BMI) 0.5 2.2 11.4 0.6 0.2 -1.6 0.0 3.4 -1.8 -0.5 -0.5 1.4
Impedance of leg (left) 0.7 3.6 8.7 -1.2 -1.6 3.0 0.0 -2.4 2.9 1.2 0.9 -1.8
Leg predicted mass (left) 1.7 9.1 25.1 2.3 2.8 -4.0 0.0 5.0 -4.1 -1.2 -1.0 3.0
Trunk fat mass 0.5 2.1 11.9 0.4 -0.0 -1.6 0.0 3.5 -1.6 -0.7 -0.6 0.9
Waist circumference 0.7 2.7 14.1 1.1 0.6 -1.4 0.0 3.8 -1.9 -0.4 -0.4 1.7
Number of incorrect matches in round 0.4 0.7 2.6 -1.1 -0.6 0.5 0.0 -1.6 1.1 0.4 0.6 -0.4
Past tobacco smoking 0.5 0.9 2.0 -0.8 1.4 -1.0 0.0 -0.9 -0.7 -1.2 -1.1 -0.7
Alcohol usually taken with meals 0.3 0.5 1.6 -0.9 -1.1 0.0 0.0 -0.5 0.6 -0.6 -0.3 -1.3
Nervous feelings 0.1 0.3 1.0 -0.4 0.0 0.6 0.0 -0.7 0.6 -0.2 -0.2 -1.0
Frequency of tenseness / restlessness in last 2 weeks 0.2 0.3 1.1 -0.2 -0.4 -1.0 0.0 0.2 -0.8 0.2 -0.4 0.5
Hearing difficulty/problems with background noise 2.4 3.9 9.3 1.1 -1.2 2.4 0.0 0.3 2.6 2.8 3.0 1.5
Hair/balding pattern: Pattern 2 0.5 0.7 2.5 1.2 1.6 -0.0 0.0 0.2 -0.4 0.4 0.5 1.2
Had menopause 0.3 0.4 1.1 -1.0 -0.6 0.5 0.0 -1.0 0.8 0.1 0.5 -0.5
Had other major operations 1.7 2.1 7.5 0.0 0.0 -2.7 0.0 1.2 -2.3 -1.3 -1.7 0.4
Forced vital capacity (FVC) 0.5 2.0 5.4 2.0 2.0 -1.4 0.0 1.3 -0.5 0.2 1.1 2.3
Heel bone mineral density (BMD) T-score, automated (right) 0.1 0.3 0.9 0.1 -0.5 -0.4 0.0 -0.8 0.1 -1.0 -0.5 -0.5
Ever unenthusiastic/disinterested for a whole week 1.1 1.3 3.9 1.2 2.0 0.1 0.0 1.7 -1.1 0.8 0.1 1.3
Qualifications: None of the above 0.7 1.6 5.2 -0.6 -2.3 1.3 0.0 -2.1 1.3 0.6 0.3 -0.8
Financial difficulties in last 2 years 2.2 3.0 7.2 0.0 1.9 -2.3 0.0 2.4 -2.7 -1.3 -1.8 0.4
Mouth/teeth dental problems 0.9 1.5 4.3 -1.6 -0.4 -0.2 0.0 -1.4 -0.1 -2.1 -1.1 -1.7
Heart attack 0.8 1.0 2.6 0.9 -0.4 1.6 0.0 -1.2 1.6 1.0 0.7 -0.4
Allergy 0.6 1.3 3.2 -0.6 0.9 1.8 0.0 -1.6 1.7 -0.3 0.4 -1.3
Pain all over the body in last month 0.3 0.3 1.5 -0.3 -0.2 -0.2 0.0 0.4 -0.4 1.2 0.5 0.9
Diabetes (self-reported) 0.3 0.4 1.5 1.2 0.1 -0.1 0.0 0.6 -0.1 0.9 0.6 0.9
Hayfever/allergic rhinitis (self-reported) 0.4 0.5 1.4 0.0 -0.8 -1.2 0.0 -0.3 -1.2 0.5 0.2 1.1
Medication: Ramipril 1.5 1.9 4.5 1.8 -1.6 1.1 0.0 -0.2 1.1 2.1 1.8 1.2
Medication: Simvastatin 0.6 0.8 1.8 0.5 -1.3 1.3 0.0 -0.3 1.2 1.0 1.2 0.1
Fluid intelligence score 0.4 0.9 3.7 -0.0 -0.5 -1.3 0.0 -0.2 -1.1 -1.9 -0.9 -0.1
Illnesses of siblings 0.6 0.9 2.7 0.6 0.8 -1.4 0.0 0.8 -1.0 0.5 0.7 1.6
Neuroticism score 0.1 0.1 0.3 -0.2 -0.4 -0.4 0.0 -0.5 -0.4 -0.2 -0.5 -0.2
Weight 1.3 6.4 24.7 2.0 1.6 -2.9 0.0 5.0 -3.1 -0.7 -0.5 2.7
Impedance of arm (right) 0.5 2.4 6.1 -0.9 -2.1 1.0 0.0 -2.4 1.1 -0.9 -1.1 -2.5
Arm fat percentage (right) 0.4 1.4 7.2 0.2 -1.0 -1.0 0.0 2.7 -1.3 -0.9 -0.9 0.4
Trunk fat-free mass 2.1 12.0 32.6 3.1 4.3 -3.7 0.0 5.7 -4.1 -0.5 -0.1 4.1
Hip circumference 1.0 4.3 16.3 2.3 0.9 -2.0 0.0 4.0 -2.6 -0.2 -0.4 2.4
Time employed in main current job 0.2 0.2 1.0 0.3 0.4 0.8 0.0 0.3 -0.1 1.0 0.1 0.4
Alcohol intake versus 10 years previously 0.9 1.4 3.4 1.5 0.2 1.8 0.0 0.6 1.4 1.4 1.4 0.5
Father’s age at death 1.7 2.3 6.3 -0.9 -2.5 2.3 0.0 -1.5 1.5 1.1 1.5 -0.3
Worrier / anxious feelings 0.5 1.0 2.5 0.5 0.6 -1.6 0.0 1.4 -1.6 -0.8 -0.3 0.6
Frequency of tiredness / lethargy in last 2 weeks 0.2 0.3 1.0 0.2 0.3 -0.4 0.0 0.9 -0.9 -0.4 -1.0 -0.1
Falls in the last year 0.7 1.0 2.8 0.8 -1.6 0.5 0.0 1.1 0.5 1.7 1.0 0.7
Hair/balding pattern: Pattern 3 0.3 0.5 1.8 0.1 0.5 -0.7 0.0 0.6 -1.0 -1.4 -0.5 -0.1
Number of live births 0.1 0.2 1.0 0.5 -1.0 0.3 0.0 -0.6 0.1 -0.4 0.1 0.2
Forced expiratory volume in 1-second (FEV1) 0.4 1.2 3.8 1.6 1.3 -1.3 0.0 0.5 -0.2 0.2 1.2 1.9
Pulse rate 0.5 0.9 3.0 1.7 -0.8 -0.8 0.0 -0.3 -1.0 -1.1 -1.2 -0.6
Happiness 1.3 1.6 5.1 -1.2 0.5 1.1 0.0 -1.0 1.0 -1.8 -1.1 -2.3
Noisy workplace 0.4 0.5 1.7 0.7 -0.6 1.1 0.0 0.3 0.9 1.3 0.2 0.0
Qualifications: A levels/AS levels or equivalent 0.9 2.0 5.9 1.9 2.4 -1.2 0.0 1.8 -1.1 -1.0 0.2 1.4
Serious illness, injury or assault of a close relative in last 2 years 1.4 1.6 4.9 1.9 1.1 -0.7 0.0 1.3 -1.3 0.5 0.6 2.2
Mouth/teeth dental problems: Dentures 0.7 1.2 5.7 0.5 0.1 1.3 0.0 0.7 1.3 2.4 0.9 0.1
Asthma 1.0 2.0 7.5 0.0 0.8 -2.5 0.0 2.7 -1.6 -0.4 -0.8 0.7
Medication: Ibuprofen (e.g. Nurofen) 0.6 0.7 2.6 1.0 0.3 0.0 0.0 1.6 -0.1 0.5 1.0 1.2
Medication: Cholesterol lowering 0.5 0.7 1.9 -1.0 0.8 -0.7 0.0 0.5 -0.2 -0.5 -1.4 -1.4
Depression (self-reported) 1.8 2.2 4.3 -1.3 -1.0 -1.8 0.0 -2.0 -0.9 -2.1 -1.7 -1.4
Medication: Lansoprazole 1.8 2.0 7.3 -1.2 -1.2 1.7 0.0 -1.2 2.7 1.0 1.1 -1.2
Prospective memory result 0.4 0.4 1.7 0.1 -0.1 1.0 0.0 -0.5 0.6 -0.7 -0.3 -1.3
Lung cancer (father) 0.5 0.6 1.6 1.0 0.8 1.3 0.0 -1.0 0.8 0.5 0.6 0.5
Illnesses of mother 1.8 2.2 6.2 0.6 -1.9 2.5 0.0 -1.3 2.0 0.3 2.1 0.1
Forced expiratory volume in 1-second (FEV1), Best measure 0.4 1.3 3.4 1.4 1.6 -1.0 0.0 -0.3 0.2 0.2 1.5 1.8
Pulse wave Arterial Stiffness index 0.3 0.3 0.7 -0.1 0.4 -0.7 0.0 0.8 -0.8 -0.8 -0.5 -0.0
Impedance of arm (left) 0.9 4.0 10.4 -1.6 -2.5 1.5 0.0 -3.2 1.7 -0.8 -1.1 -3.2
Arm fat mass (right) 0.7 3.1 15.8 1.1 0.3 -1.7 0.0 4.0 -2.0 -0.6 -0.5 1.6
Trunk predicted mass 2.0 11.6 30.9 3.0 4.2 -3.7 0.0 5.6 -4.0 -0.5 -0.1 4.1
Standing height 0.8 7.8 16.3 3.1 3.6 -3.4 0.0 4.0 -3.3 -0.6 -0.1 2.9
Length of working week for main job 2.8 3.2 11.0 0.5 0.2 -3.3 0.0 2.3 -2.7 -0.5 -0.7 1.8
Exposure to tobacco smoke at home 1.3 1.5 3.7 -1.6 -0.2 -1.5 0.0 1.4 -1.2 -0.9 -1.9 -0.7
Breastfed as a baby 1.4 1.8 5.6 2.4 0.5 -0.9 0.0 1.4 -0.9 1.3 0.7 2.2
Tense / ‘highly strung’ 0.9 1.6 4.2 1.3 -0.2 2.1 0.0 -0.2 1.4 1.9 1.4 0.5
Seen doctor (GP) for nerves, anxiety, tension or depression 0.4 0.6 2.0 -0.6 -0.6 -1.4 0.0 -0.0 -0.9 -0.4 -1.2 -0.5
Hair/balding pattern: Pattern 4 0.2 0.6 2.4 -0.5 -0.4 0.4 0.0 -0.9 1.1 -0.1 -0.6 -1.5
Birth weight of first child 2.0 3.6 8.9 1.6 -1.4 2.2 0.0 -1.0 2.1 2.6 3.0 1.3
Peak expiratory flow (PEF) 1.2 2.7 6.7 1.7 1.1 -1.1 0.0 2.5 -0.1 1.5 1.9 2.6
Pulse wave reflection index 1.4 1.7 3.5 0.9 1.6 0.7 0.0 1.3 0.1 1.8 1.6 1.9
Ever highly irritable/argumentative for 2 days 0.7 0.8 2.7 0.4 0.5 1.7 0.0 1.1 1.1 0.9 0.8 -0.2
Loud music exposure frequency 0.4 0.5 1.5 0.4 1.2 -0.6 0.0 1.2 -0.2 0.2 -0.7 -0.2
Qualifications: O levels/GCSEs or equivalent 0.4 0.6 1.4 1.1 0.8 -0.7 0.0 0.8 -1.0 -0.3 -0.0 1.2
Mouth/teeth dental problems: Bleeding gums 0.7 0.9 2.0 1.2 -0.8 0.9 0.0 -0.5 0.9 0.6 1.4 1.1
Blood clot in the leg (DVT) 0.1 0.1 0.6 0.8 -0.5 0.0 0.0 -0.1 -0.1 -0.1 0.2 0.6
Medication: Paracetamol 0.2 0.3 0.7 0.6 -0.8 0.2 0.0 0.5 0.5 0.7 0.5 0.4
Headache pain in last month 0.4 0.6 3.3 0.3 0.4 -0.7 0.0 1.8 -0.7 0.3 -0.2 0.9
Medication for cholesterol, blood pressure or diabetes 0.5 0.8 2.5 0.2 -1.4 0.7 0.0 -1.6 -0.1 0.2 1.0 1.0
Glaucoma (self-reported) 3.1 3.6 7.7 -2.8 -1.7 -1.3 0.0 -1.5 -0.9 -2.5 -2.3 -2.3
Gout (self-reported) 0.8 1.1 3.0 0.6 -1.0 -1.6 0.0 0.9 -1.7 -1.1 -1.2 -0.0
Hypothyroidism/myxoedema (self-reported) 0.1 0.3 1.0 0.5 1.0 0.3 0.0 0.8 -0.3 0.4 -0.4 0.3
Medication: Amlodipine 0.3 0.5 2.2 -0.3 -0.2 0.7 0.0 0.4 0.5 -0.2 -1.0 -1.5
Medication: Ventolin 100micrograms inhaler 0.5 0.7 1.8 0.7 -0.0 1.3 0.0 0.6 1.1 1.0 1.1 0.5
Birth weight 0.2 0.4 1.4 1.2 -0.2 -0.6 0.0 -0.1 -0.8 -0.2 0.5 0.7
Chronic bronchitis/emphysema (mother) 0.4 0.4 2.1 0.7 0.8 -0.1 0.0 -1.5 -0.1 0.1 -0.5 -0.1
High blood pressure (siblings) 1.0 1.5 3.8 -1.8 -1.7 0.3 0.0 -1.0 0.8 -1.1 -0.8 -2.0
Forced vital capacity (FVC), Best measure 0.5 1.8 5.0 1.7 2.2 -1.6 0.0 0.3 -0.7 -0.2 0.9 2.0
Body fat percentage 0.2 0.9 5.6 -0.1 -1.3 -0.5 0.0 2.4 -0.7 -0.4 -0.6 0.1
Leg fat percentage (right) 0.2 0.8 4.7 0.6 -1.0 0.3 0.0 2.2 -0.0 0.4 0.3 0.7
Arm fat-free mass (right) 1.7 9.0 28.0 2.1 3.4 -3.4 0.0 5.3 -3.4 -0.1 0.3 3.7
Exposure to tobacco smoke outside home 1.3 1.7 7.3 -0.5 -0.5 2.3 0.0 -0.6 2.7 0.2 1.1 -0.8
Comparative body size at age 10 1.3 3.5 8.7 -1.9 0.4 -2.3 0.0 0.1 -2.3 -3.0 -2.5 -1.4
Number of full brothers 0.4 0.5 1.5 0.1 0.6 -0.1 0.0 1.2 0.1 1.1 0.5 1.2
Worry too long after embarrassment 1.1 1.8 4.8 1.1 1.1 0.4 0.0 0.4 0.8 2.0 2.2 1.9
Seen a psychiatrist for nerves, anxiety, tension or depression 0.8 1.0 3.3 -1.3 -1.5 0.2 0.0 -1.8 0.7 -0.6 -0.1 -1.1
Wheeze or whistling in the chest in last year 0.2 0.3 1.2 0.2 -1.1 -0.6 0.0 0.5 -0.6 0.1 -0.5 0.5
Number of children fathered 0.9 1.0 4.3 2.1 0.4 0.8 0.0 0.4 0.4 0.9 1.1 1.3
Reason for reducing amount of alcohol drunk: Health precaution 1.3 1.5 5.1 -0.5 0.2 -2.3 0.0 1.1 -2.0 -1.5 -1.1 0.1
Age at first live birth 0.8 1.4 5.7 -2.4 -0.6 0.1 0.0 -1.3 0.5 -1.3 -0.5 -1.6
Pulse wave peak to peak time 0.2 0.2 0.5 0.2 -0.3 0.4 0.0 -0.5 0.6 0.7 0.5 0.2
Health satisfaction 0.6 0.8 2.2 -1.1 -0.1 1.5 0.0 0.7 0.8 0.4 -0.3 -1.5
Shortness of breath walking on level ground 0.2 0.3 1.5 0.1 0.2 0.7 0.0 1.2 0.6 -0.0 0.0 -0.4
Qualifications: College or University degree 0.5 1.7 4.6 0.2 1.4 -2.1 0.0 0.8 -1.5 -2.1 -1.0 -0.2
Eye problems/disorders: None of the above 0.4 0.5 1.9 1.0 1.4 0.3 0.0 0.4 -0.3 0.3 0.3 1.1
Mouth/teeth dental problems: Loose teeth 3.0 3.5 6.5 2.3 -1.0 1.4 0.0 2.2 0.9 2.6 2.4 2.3
Emphysema/chronic bronchitis 0.8 0.8 4.5 0.5 -2.1 0.6 0.0 -0.3 0.9 1.1 0.5 -0.2
Medication for pain relief, constipation, heartburn 0.2 0.4 1.4 -0.6 -0.3 -0.6 0.0 -0.6 -0.7 -1.2 -0.6 0.0
Neck or shoulder pain in last month 0.3 0.4 1.1 -0.1 0.7 1.1 0.0 -0.2 0.9 0.2 -0.2 -0.9
Medication: Blood pressure 0.6 1.1 5.9 0.1 1.6 -0.6 0.0 2.4 -0.0 0.2 -0.9 -0.5
Angina (self-reported) 0.5 0.7 2.6 -1.1 0.6 0.7 0.0 -0.5 0.5 0.2 -0.8 -1.6
Migraine (self-reported) 0.8 1.0 3.3 -0.6 -1.8 1.0 0.0 -1.1 1.4 -0.4 0.2 -0.8
Medication: Ibuprofen 1.1 1.3 4.5 1.3 0.1 0.4 0.0 2.1 0.7 0.9 1.5 1.3
Medication: Allopurinol 0.7 0.9 3.1 0.3 -1.0 -1.6 0.0 0.7 -1.8 -0.3 -0.7 0.7
Medication: Omeprazole 0.7 0.9 2.2 -0.5 0.2 -0.8 0.0 1.1 -0.9 -0.8 -1.5 -1.3
Medication: Seretide 50 evohaler 0.3 0.4 1.0 -0.3 -0.1 -0.7 0.0 -1.0 -0.3 -0.8 -0.9 -0.5
Mean time to correctly identify matches 0.6 1.2 4.2 0.4 -0.7 -1.2 0.0 1.7 -2.0 -0.2 -1.1 0.6
Heart disease (mother) 1.3 1.6 3.6 -0.8 1.9 -1.4 0.0 1.0 -1.3 -1.3 -1.9 -0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.5 0.6 2.3 -0.2 0.3 0.6 0.0 1.5 -0.1 1.2 0.7 0.6
Whole body fat mass 0.6 2.7 14.5 0.7 0.2 -1.8 0.0 3.8 -1.9 -0.7 -0.7 1.2
Leg fat mass (right) 0.6 2.4 13.2 0.9 0.3 -1.4 0.0 3.6 -1.6 -0.2 -0.2 1.6
Arm predicted mass (right) 1.7 8.8 26.7 2.2 3.6 -3.1 0.0 5.2 -3.2 -0.0 0.4 3.7
Pulse rate, automated reading 0.6 2.1 6.4 -0.3 -2.5 0.6 0.0 -2.2 0.4 -1.1 -1.1 -2.2
Alcohol intake frequency. 0.7 1.5 3.8 0.8 -1.4 2.0 0.0 -0.5 1.7 1.7 1.3 0.1
Comparative height size at age 10 0.5 2.9 10.4 0.7 2.3 -2.0 0.0 3.2 -2.0 -0.8 -0.3 0.9
Number of full sisters 0.7 0.9 2.3 -0.7 -0.7 -1.0 0.0 -0.7 -0.5 -1.3 -1.5 -1.0
Suffer from ‘nerves’ 0.7 1.1 2.9 -0.9 -1.1 -1.0 0.0 -1.7 -0.9 -0.9 -1.3 -1.1
Overall health rating 0.3 0.7 3.3 1.4 0.1 0.4 0.0 1.8 -0.5 -0.0 -0.8 0.1
Chest pain or discomfort 0.7 1.0 2.8 -1.1 -1.4 0.8 0.0 -1.0 0.9 -0.4 -0.8 -1.7
Had major operations 0.2 0.2 0.8 -0.0 0.5 -0.9 0.0 0.3 -0.4 -0.7 -0.1 -0.3
Age at last live birth 0.4 0.5 2.6 -1.6 -0.5 -0.9 0.0 0.7 -0.2 -0.5 -0.4 -0.4
Family relationship satisfaction 0.7 0.9 3.7 0.2 -0.1 1.4 0.0 -1.2 1.9 0.3 0.8 -0.4
Leg pain on walking 0.5 0.7 1.4 0.2 -1.1 0.2 0.0 0.2 0.7 1.2 1.2 1.2
Qualifications: NVQ or HND or HNC or equivalent 0.3 0.4 1.3 0.2 -0.4 1.1 0.0 -0.0 1.1 0.1 0.6 -0.4
Commuting to job workplace: Car/motor vehicle 0.3 0.3 0.9 0.0 0.8 -0.0 0.0 -0.5 0.7 0.4 0.9 0.3
Illness, injury, bereavement, stress in last 2 years 0.7 0.8 3.2 -0.9 0.1 0.8 0.0 -1.2 1.8 0.0 0.9 -0.8
Medication: Aspirin 0.2 0.3 1.0 0.9 1.0 -0.2 0.0 0.6 0.1 0.4 0.1 -0.1
Supplements: Vitamin C 0.1 0.1 0.3 0.5 0.1 -0.2 0.0 0.0 -0.1 -0.6 0.3 0.3
Knee pain experienced in last month 0.5 0.8 2.2 0.8 -1.3 -1.3 0.0 0.1 -1.5 0.1 -0.8 0.9
Hypertension (Self-reported) 0.4 1.1 6.3 -0.3 0.4 -0.2 0.0 2.5 0.2 -0.8 -1.1 -1.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.1 0.1 0.7 -0.2 -0.1 0.2 0.0 0.3 0.6 0.2 0.0 -0.9
Illnesses of father: Heart disease 0.4 0.6 2.5 0.1 1.6 -0.5 0.0 0.8 -1.0 -0.3 -0.3 0.6
Illnesses of siblings: Diabetes 0.7 0.9 3.9 -0.5 -0.9 2.0 0.0 -0.6 1.4 0.3 0.4 -0.8
Smoking status: Previous 0.5 0.7 1.7 0.3 -1.0 0.9 0.0 1.3 0.6 1.1 1.0 0.4
Forced expiratory volume in 1-second (FEV1), predicted 0.9 1.9 5.2 0.5 1.1 -2.3 0.0 1.2 -2.2 -1.6 -1.1 0.4
Whole body fat-free mass 1.9 11.0 31.6 2.6 3.6 -3.9 0.0 5.6 -4.2 -0.8 -0.4 3.7
Leg fat-free mass (right) 1.7 9.0 25.3 2.1 2.8 -4.0 0.0 5.0 -4.0 -1.2 -1.0 3.0
Arm fat percentage (left) 0.3 1.2 5.6 -0.3 -1.1 -1.0 0.0 2.4 -1.1 -1.0 -1.0 0.1
Average weekly red wine intake 0.9 1.4 3.4 -0.8 -0.6 1.8 0.0 -1.6 1.9 -0.2 0.8 -1.3
Handedness (chirality/laterality): Left-handed 0.2 0.3 0.7 0.6 -0.2 -0.9 0.0 0.5 -0.8 -0.4 0.0 0.3
Mood swings 0.3 0.5 1.7 -0.4 0.2 -1.3 0.0 0.5 -1.2 -0.2 -0.9 -0.0
Loneliness, isolation 0.2 0.3 0.8 -0.4 -0.6 -0.3 0.0 -0.1 -0.1 -0.5 -0.9 -0.9
Long-standing illness, disability or infirmity 0.6 0.9 4.2 0.4 0.4 -0.9 0.0 0.5 -1.2 -0.7 -2.0 -0.6
Ever had bowel cancer screening 1.1 1.3 4.6 -0.5 -0.4 -1.6 0.0 2.1 -1.8 -0.2 -0.7 0.3
Diabetes diagnosed by doctor 0.2 0.4 1.2 1.1 0.8 -0.5 0.0 0.8 -0.5 0.1 0.1 0.6
Ever had stillbirth, spontaneous miscarriage or termination 1.2 1.3 3.4 -0.2 -1.2 1.8 0.0 -1.2 1.6 1.2 0.9 -0.3
Friendships satisfaction 0.8 0.9 3.3 -0.7 1.8 0.6 0.0 0.1 0.5 -1.4 -0.6 -1.4
Qualifications: nursing, teaching 0.8 1.2 5.6 0.2 1.4 -1.1 0.0 2.4 -0.7 0.2 0.3 1.3
Commuting to job workplace: Walk 0.8 0.9 2.3 -1.1 -1.2 -0.6 0.0 0.5 -0.4 -0.8 -1.3 -1.5
Eye problems/disorders: Cataract 1.3 1.5 3.4 0.8 -1.6 1.9 0.0 -1.5 1.5 0.7 1.3 0.1
Mouth/teeth dental problems: Mouth ulcers 2.1 3.3 7.6 1.5 1.0 -2.5 0.0 2.8 -2.7 0.4 -0.6 2.2
Medication for cholesterol 0.4 0.6 2.1 -1.1 1.2 -1.4 0.0 0.1 -0.7 -0.1 -0.3 0.6
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.5 0.6 1.8 0.6 -0.4 0.9 0.0 0.2 1.0 1.3 1.1 0.1
Back pain experienced in last month 2.1 3.1 8.6 2.9 -0.6 1.0 0.0 1.0 0.3 2.8 1.8 2.5
Mineral and other dietary supplements 0.1 0.2 0.7 -0.0 -0.8 0.2 0.0 0.1 0.3 -0.3 -0.5 -0.7
Breast cancer (self-reported) 0.3 0.4 1.1 -0.2 -1.1 -0.7 0.0 0.9 -0.5 -0.7 -0.6 -0.3
Asthma (self-reported) 1.1 2.2 7.8 0.1 0.8 -2.6 0.0 2.8 -1.7 -0.3 -0.9 0.8
Osteoporosis (self-reported) 0.7 0.9 3.2 -0.9 0.5 -1.2 0.0 -0.3 -0.6 -1.8 -0.9 -1.1
Osteoarthritis (self-reported) 0.9 1.2 3.7 -0.4 -1.9 -1.1 0.0 0.2 -1.2 -0.8 -1.7 -0.9
Medication: Aspirin 0.3 0.4 0.7 0.8 0.6 0.6 0.0 0.8 0.7 0.7 0.5 -0.3
Medication: Gliclazide 0.3 0.4 1.2 -0.7 1.1 0.7 0.0 0.0 0.7 -0.5 -0.0 -0.8
Illnesses of father: None of the above (group 1) 0.4 0.5 2.1 0.3 -1.4 0.0 0.0 -1.3 0.1 -0.4 0.1 0.0
Smoking status: Current 0.5 0.8 2.5 0.9 0.4 -0.9 0.0 -1.0 -1.1 -0.8 -1.6 -0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.6 1.3 3.6 1.1 1.3 -1.2 0.0 0.9 -1.5 -0.1 0.5 1.9
Whole body water mass 2.0 11.2 32.5 2.7 3.8 -3.9 0.0 5.7 -4.1 -0.7 -0.3 3.8
Leg predicted mass (right) 1.7 8.8 25.3 2.2 2.7 -3.9 0.0 5.0 -3.9 -1.1 -0.9 3.0
Arm fat mass (left) 0.7 2.8 14.3 0.7 0.2 -1.9 0.0 3.8 -2.0 -0.8 -0.6 1.4
Number of self-reported non-cancer illnesses 0.4 0.8 4.4 0.2 -0.6 -0.9 0.0 2.1 -0.8 0.7 -0.4 0.2
Average weekly champagne plus white wine intake 1.4 1.9 6.8 -0.9 -0.4 -2.4 0.0 0.7 -2.6 -0.7 -1.5 -0.1
Miserableness 0.2 0.3 0.7 -0.0 -0.3 -0.8 0.0 0.8 -0.8 0.3 -0.4 0.7
Guilty feelings 1.3 2.0 7.4 1.9 -1.3 -0.3 0.0 0.4 -0.3 1.5 1.5 2.7
Wears glasses or contact lenses 0.8 0.9 2.6 1.3 -1.6 1.1 0.0 -0.1 0.6 1.0 0.9 0.4
Ever taken oral contraceptive pill 1.2 1.4 4.3 -2.1 0.5 -1.2 0.0 -0.9 -0.1 -1.2 -1.3 -1.6
Hearing aid user 0.3 0.3 1.1 0.7 0.4 0.3 0.0 -0.5 1.0 0.0 1.0 0.2
Mother’s age at death 0.9 1.1 3.4 -1.1 -1.0 -1.8 0.0 0.9 -1.4 -0.8 -0.9 0.1
Financial situation satisfaction 0.7 0.8 2.4 -0.9 0.6 -0.8 0.0 1.2 -1.0 -0.6 -1.5 -0.6
Tinnitus: Yes, now most or all of the time 0.6 0.7 3.2 1.8 0.4 -0.5 0.0 1.4 -0.3 -0.2 -0.8 0.1
Commuting to job workplace: Public transport 1.1 1.3 5.4 0.1 -0.0 -0.2 0.0 0.3 -1.5 -1.5 -2.3 -1.1
Eye problems/disorders: Glaucoma 2.3 2.7 6.1 -2.5 -1.3 -0.8 0.0 -0.9 -0.6 -2.2 -2.0 -2.4
Medication: Blood pressure 0.6 1.1 3.9 2.0 0.1 1.3 0.0 1.4 0.7 0.8 1.0 0.8
Pain type(s) experienced in last month: Hip pain 1.4 1.8 4.1 1.7 -0.1 1.6 0.0 -1.3 1.2 2.0 1.6 1.0
Supplements: Fish oil (including cod liver oil) 0.3 0.4 1.0 -0.1 0.8 -1.0 0.0 -0.5 -0.9 -0.7 -0.5 0.3
High cholesterol (Self-reported) 0.4 0.7 2.9 1.7 -0.7 0.0 0.0 1.1 -0.9 0.5 -0.2 0.5
Medication: Bendroflumethiazide 1.2 1.8 8.8 2.1 1.4 0.0 0.0 3.0 -0.6 -0.0 -0.1 0.7
Medication: Paracetamol 0.5 0.7 1.8 -1.0 -1.3 -0.5 0.0 0.7 0.0 -0.8 -1.0 -1.1
Medication: Lisinopril 0.1 0.1 0.3 0.3 0.4 0.5 0.0 0.6 -0.0 0.0 0.0 0.2
Medication: Atorvastatin 1.3 1.6 4.9 1.0 0.7 -1.7 0.0 2.2 -1.7 -0.7 -1.6 -0.2
Illnesses of father: High blood pressure 0.9 1.1 6.0 0.6 1.8 -0.1 0.0 2.5 -0.2 0.3 -0.4 0.6
Alcohol drinker status: Never 0.6 0.7 2.0 -0.1 -1.4 1.2 0.0 -0.8 1.2 -0.0 0.9 -0.4
Ever smoked 0.5 0.9 2.2 1.2 -0.7 0.8 0.0 0.4 0.6 1.5 1.3 1.2
Basal metabolic rate 1.9 10.4 32.4 2.7 3.2 -3.7 0.0 5.7 -3.9 -0.7 -0.4 3.6
Leg fat percentage (left) 0.2 0.8 5.0 0.2 -1.2 0.3 0.0 2.2 0.1 0.4 0.3 0.5
Arm fat-free mass (left) 1.9 9.9 32.1 2.7 3.3 -3.1 0.0 5.7 -3.4 0.0 0.5 4.2
Number of operations (self-reported) 2.4 3.5 11.4 0.2 0.9 -3.4 0.0 2.4 -3.1 -0.7 -1.6 0.9
Average weekly beer plus cider intake 1.4 2.0 3.6 1.0 -1.6 1.6 0.0 -0.5 1.9 1.8 1.9 0.8
Irritability 0.6 1.0 3.1 -1.8 -1.2 0.1 0.0 -1.0 0.6 -0.7 -0.5 -1.6
Risk taking 0.8 1.1 3.0 -1.3 -1.0 -0.4 0.0 -1.1 -0.1 -0.3 -1.7 -1.7
Ever had prostate specific antigen (PSA) test 1.5 1.7 5.3 -1.9 -1.7 0.2 0.0 -0.3 0.4 -1.0 -1.5 -2.3
Fractured/broken bones in last 5 years 0.4 0.5 2.9 -1.7 0.8 -0.5 0.0 0.7 -0.2 -0.3 -0.4 -0.5
Age started oral contraceptive pill 1.0 1.2 3.5 -1.7 -0.2 1.1 0.0 -1.9 0.6 -0.1 -0.4 -1.7
Diastolic blood pressure, automated reading 1.0 3.2 18.1 0.3 2.8 -0.5 0.0 4.3 -1.3 0.2 -0.8 0.7
Ever depressed for a whole week 0.5 0.6 2.4 0.6 -0.5 -0.4 0.0 0.8 -0.7 0.9 0.8 1.5
Unable to work because of sickness or disability 0.5 0.6 1.7 1.3 -0.7 0.9 0.0 0.2 1.0 1.1 0.5 0.0
Commuting to job workplace: Cycle 0.8 1.0 3.7 0.2 -0.8 0.9 0.0 -1.9 1.0 1.1 1.1 0.7
Myopia 0.8 1.2 3.4 0.8 1.2 -1.1 0.0 1.4 -1.1 0.4 0.6 1.8
Vascular/heart problems diagnosed by doctor 0.3 0.9 5.6 -0.1 -0.6 -0.1 0.0 -2.4 -0.2 0.3 0.9 1.0
Cholesterol lowering medication 2.0 2.9 7.5 2.7 -1.9 1.8 0.0 1.4 0.6 1.8 2.0 1.6
Medication: Omeprazole (e.g. Zanprol) 0.6 0.7 2.7 -0.5 -0.3 -0.6 0.0 0.4 -0.4 -0.6 -1.4 -1.6
Pain experienced in last month 0.6 0.9 2.0 -1.4 -0.5 0.9 0.0 -1.4 1.2 -0.2 0.3 -1.3
Supplements: Calcium 2.2 2.5 5.4 -2.0 -2.0 -0.5 0.0 -1.6 0.3 -2.3 -1.0 -2.2
Basal cell carcinoma (self-reported) 1.1 1.3 4.3 -0.1 -0.1 -1.9 0.0 0.7 -2.1 -1.6 -0.8 0.3
Heart attack/myocardial infarction (self-reported) 0.7 0.9 2.3 0.7 -0.3 1.5 0.0 -1.1 1.5 0.9 0.5 -0.6
Deep venous thrombosis (DVT) (self-reported) 0.1 0.1 0.4 0.6 -0.5 -0.1 0.0 -0.0 -0.2 0.0 0.0 0.5
Heart disease (siblings) 0.2 0.2 0.5 0.3 0.3 0.6 0.0 0.3 0.2 0.4 -0.7 -0.6
Alcohol drinker status: Previous 0.3 0.4 1.1 -0.6 -0.7 -1.0 0.0 0.3 -0.8 0.3 -0.9 -0.0
Pack years of smoking 1.1 1.6 5.1 -2.2 -0.2 -1.2 0.0 0.0 -1.0 -1.1 -2.3 -1.1
Impedance of whole body 0.8 4.3 11.3 -1.7 -2.3 2.1 0.0 -3.4 2.3 -0.2 -0.5 -3.0
Leg fat mass (left) 0.6 2.5 14.7 0.8 0.3 -1.5 0.0 3.8 -1.6 -0.2 -0.2 1.5
Arm predicted mass (left) 2.1 10.5 34.5 2.8 3.4 -3.1 0.0 5.9 -3.5 0.3 0.6 4.4