Hub : Genes

FKBP15

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Cells Transformed fibroblasts 0.2590 0.0700 3.6e-05 0.064 NA 0.046 NA 0.060 1.4e-05 NA 2.1e-04 NA 2.8e-05
2 GTEx Esophagus Muscularis 0.1410 0.0450 3.0e-04 0.079 NA 0.045 NA 0.053 1.6e-05 NA 9.7e-04 NA 3.7e-04
3 GTEx Muscle Skeletal 0.2077 0.0392 3.1e-12 0.148 NA 0.184 NA 0.188 2.1e-14 NA 8.5e-18 NA 3.5e-18
4 GTEx Skin Not Sun Exposed Suprapubic 0.1750 0.0640 1.3e-03 0.006 NA 0.005 NA 0.007 1.4e-01 NA 1.6e-01 NA 1.3e-01
5 GTEx Skin Sun Exposed Lower leg 0.1410 0.0420 2.4e-04 0.083 NA 0.053 NA 0.063 2.3e-07 NA 3.1e-05 NA 6.6e-06
6 GTEx Whole Blood 0.0860 0.0320 3.2e-03 0.036 NA 0.016 NA 0.034 2.7e-04 NA 1.2e-02 NA 3.6e-04
7 NTR Blood 0.0399 0.0122 1.2e-05 0.011 0.008 0.013 0.016 0.012 9.3e-05 1.3e-03 3.8e-05 4.9e-06 4.8e-05
8 YFS Blood 0.0863 0.0177 4.7e-15 0.036 0.062 0.066 0.072 0.065 5.4e-12 1.9e-19 8.4e-21 2.2e-22 1.6e-20

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.3 0.4 1.5 1.2 0.6 0.4 0.5 0.6 -0.7 -0.7 -0.1
Bipolar Disorder or Schizophrenia 0.2 0.6 1.7 -0.7 0.4 -0.5 -0.1 -1.3 -0.5 0.4 1.3
Depressed Affect (Nagel 2018) 1.0 2.0 5.2 1.4 0.1 2.3 0.6 0.8 -1.5 -1.4 -1.9
Depression (Nagel 2018) 0.5 0.8 1.8 1.1 0.5 0.7 1.4 0.9 -0.3 -0.8 -1.0
Intelligence (Savage-Jansen 2018) 0.3 0.9 3.4 0.4 0.5 -1.4 -0.0 0.5 1.8 1.1 0.6
Neuroticism (Nagel 2018) 0.7 1.6 2.8 1.5 1.4 1.5 0.1 1.2 -1.1 -1.0 -1.7
Schizophrenia (2018) 0.8 1.7 4.5 -1.9 0.0 -1.0 -0.6 -2.1 -0.1 1.1 1.7
Schizophrenia vs Biploar Disorder 1.6 2.2 5.0 -2.1 -0.8 -0.4 0.3 -1.9 0.3 1.9 2.2
Worry (Nagel 2018) 0.1 0.2 1.4 0.2 1.2 -0.0 0.4 -0.0 -0.1 0.0 -0.1
Alzheimer’s Disease (in mother) 0.4 0.4 1.6 -0.8 -1.3 -0.3 -0.7 -0.1 0.7 0.4 -0.0
Alzheimer’s Disease (in father) 0.2 0.2 0.7 -0.1 -0.5 -0.2 -0.1 0.6 0.8 -0.6 -0.2
Alzheimer’s Disease (including proxy) 0.3 0.5 1.1 -1.0 -1.0 -0.2 -0.7 0.4 1.0 0.3 -0.1
Crohns Disease (2017) 0.2 0.5 1.2 -0.8 -0.8 -0.5 -0.8 -0.1 1.1 -0.4 -0.3
Irritable Bowel Disease (IBD) 0.3 0.8 4.2 -0.1 -1.0 -0.7 -0.2 0.9 2.0 -0.3 -0.0
Ulcerative Colitis (UC) 0.6 1.1 4.2 0.7 -0.4 -0.5 0.7 1.7 2.1 -0.7 -0.2
Major Depression (MDD) 0.4 0.4 1.3 0.3 -0.5 0.9 0.8 0.4 0.0 -0.5 1.1
Reaction Time 0.7 1.3 4.2 -1.4 0.0 -1.0 -0.3 -0.6 2.1 0.5 1.5
Verbal and Numeric Reasoning (VNR) 0.1 0.2 0.7 0.2 -0.2 -0.1 0.9 0.8 0.7 -0.2 0.0
Breast Cancer 0.5 1.3 3.4 -0.7 -1.4 -0.1 -1.8 0.1 1.7 -0.6 -0.8
Ovarian Cancer 0.9 1.2 3.0 0.3 0.4 1.2 1.2 0.1 -0.8 1.6 1.7
Prostate Cancer 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Age at First Birth 0.7 1.1 4.3 2.1 -0.1 0.1 1.2 1.5 -0.5 0.0 -0.7
Bipolar Disorder (2011) 0.2 0.2 1.0 0.3 0.5 -0.2 1.0 0.2 0.1 -0.1 0.4
Body Mass Index (BMI) (2010) 0.3 0.5 1.3 0.8 0.9 0.7 0.4 0.2 -1.2 -0.4 -0.1
Coronary Artery Disease (CAD) 0.9 1.0 4.9 -0.6 -0.7 -0.4 -2.2 -1.1 0.3 0.8 0.6
Crohns Disease (2012) 0.6 0.9 2.2 -1.2 -1.2 -0.7 -1.1 -0.4 1.5 -0.1 -0.2
Mean Putamen Volume 1.1 1.2 4.3 -0.5 -0.6 -2.1 1.4 -0.4 1.2 -1.1 0.4
Fasting Glucose 0.5 0.6 2.7 0.7 -0.0 1.1 1.6 0.5 -0.1 -0.2 0.2
HbA1C 1.0 1.1 2.6 0.4 1.2 -0.2 1.6 0.6 -0.5 -1.5 -1.4
HDL Cholesterol 1.2 2.0 5.6 1.1 2.4 0.2 1.8 2.3 -0.1 -0.2 -0.6
LDL Cholesterol 0.3 0.5 2.9 0.5 0.3 -0.6 1.7 0.7 -0.2 -0.2 -0.1
Lupus 0.4 0.6 2.9 0.7 -0.0 0.7 -0.5 -0.5 -1.7 -0.0 -0.7
Neuroticism (2016) 1.4 2.0 7.0 0.9 0.4 1.1 0.6 1.6 0.0 -2.0 -2.6
Primary Biliary Cirrhosis 0.6 0.8 1.6 0.8 1.0 -0.9 1.1 0.2 0.3 1.1 1.3
Rheumatoid Arthritis 0.5 0.7 3.1 0.4 -0.3 1.8 -0.1 0.1 -1.2 -0.6 -0.2
Schizophrenia (2014) 0.2 0.4 0.7 -0.7 -0.7 0.5 -0.6 -0.8 0.2 0.8 0.7
Triglycerides 0.8 1.4 3.6 0.8 -0.6 0.2 -1.9 0.6 -0.8 -1.6 -1.7
Type 2 Diabetes (T2D) (2012) 1.0 1.1 5.4 0.8 -0.6 1.4 -0.9 0.1 0.2 -0.3 -2.3
Ulcerative Colitis 0.4 0.5 2.0 0.4 0.0 -0.5 0.2 1.2 1.4 0.3 0.5
Blood Eosinophil Count 0.1 1.1 3.0 1.4 0.9 1.6 -0.1 0.3 -1.7 0.2 -0.5
Blood Platelet Count 0.3 4.0 13.5 1.0 1.1 1.7 -3.7 1.1 -0.7 -2.2 -2.5
Blood Red Count 0.2 1.9 7.6 -0.1 -2.4 0.7 2.8 -0.4 0.1 -0.8 0.9
Blood White Count 1.9 14.0 25.8 -3.5 -3.5 -5.1 -0.7 -4.4 4.2 3.0 3.9
Heel T-Score 0.1 1.1 3.1 -1.8 -1.0 -0.7 -1.4 -0.5 1.6 0.2 -0.1
BMI 0.5 2.6 7.9 1.6 2.7 1.2 -0.1 0.5 -2.8 -0.4 -1.2
Height 1.0 19.6 46.8 -0.9 1.1 -5.2 3.8 0.0 4.7 6.8 6.7
Waist Hip Ratio (WHR) 0.6 2.5 6.5 -2.3 -0.1 -0.3 -1.2 -2.6 -0.0 2.0 1.6
Systolic Blood Pressure 0.1 0.5 2.9 0.1 0.3 -0.1 -1.7 -0.8 -0.2 -0.5 -0.3
Smoking Status 0.5 1.1 3.8 2.0 0.8 1.1 -0.5 0.7 -1.4 0.3 0.4
Allergy or Eczema 0.6 1.7 4.9 -1.1 0.9 -1.6 -2.2 -1.4 0.2 1.0 1.1
Cardiovascular Disease 0.4 1.3 6.6 0.9 2.6 0.4 0.5 -0.2 -1.5 -0.0 0.2
Hypothyroidism (self reported) 0.5 1.2 3.5 -0.9 -0.1 -0.5 1.9 -0.8 0.0 1.3 1.6
Respiratory disease 0.1 0.3 1.4 0.7 1.2 0.5 -0.5 0.5 -0.1 0.3 0.0
Type 2 Diabetes (T2D) (2018) 0.2 0.3 0.8 -0.0 0.1 -0.4 -0.7 -0.8 -0.7 0.9 0.2
Lung FEV1/FVC ratio 0.1 0.6 1.9 -0.7 -0.8 1.4 -0.1 0.2 0.9 -0.5 -1.0
Lung FVC 0.5 2.8 7.6 -1.7 -2.0 -1.8 -0.3 -0.5 2.8 1.1 1.7
Neuroticism 0.7 1.7 3.0 1.0 1.4 1.0 1.6 1.4 -0.3 -1.3 -1.7
Chronotype (morning person) 0.6 1.5 3.7 -1.0 -0.4 -1.4 0.1 -0.7 1.6 1.9 1.3
Hair Pigment 0.1 4.1 9.5 -2.4 -0.6 -2.5 -1.6 -3.1 1.4 2.0 1.4
Tanning 0.3 4.0 10.9 1.8 1.7 3.0 -0.7 0.8 -3.3 -1.2 -1.9
Hand grip strength (left) 0.4 1.0 4.0 0.7 0.7 -1.0 -0.2 -0.3 0.1 2.0 1.2
Number of treatments/medications taken 0.9 1.6 3.8 0.5 1.9 0.4 1.9 0.6 -0.9 -1.4 -1.5
Average weekly spirits intake 1.9 2.3 4.4 -0.7 -1.6 -0.6 -2.1 -1.3 1.8 2.1 1.3
Sensitivity / hurt feelings 0.7 1.1 4.0 1.0 0.5 0.1 0.4 1.3 -0.3 -2.0 -1.4
Frequency of depressed mood in last 2 weeks 0.4 0.6 1.6 0.0 -0.5 -0.1 1.2 0.7 1.3 -0.6 -0.6
Hearing difficulty/problems: Yes 0.7 1.1 5.2 -1.5 -0.5 -0.4 2.3 -1.0 0.3 -0.2 -0.4
Relative age of first facial hair 0.7 1.5 4.4 -0.9 -2.1 1.6 0.4 -0.6 -0.3 -0.6 -1.8
Other serious medical condition/disability diagnosed by doctor 0.2 0.3 2.2 -0.4 0.0 0.1 1.5 -0.1 -0.3 0.0 -0.0
Ever used hormone-replacement therapy (HRT) 0.3 0.3 1.0 0.4 0.6 0.6 1.0 0.7 0.5 0.0 0.2
Ever had hysterectomy (womb removed) 1.2 1.4 3.6 -0.7 -0.9 -0.8 -1.2 -1.0 0.8 1.9 1.6
Systolic blood pressure, automated reading 0.3 0.7 1.6 0.9 0.7 1.3 -0.7 0.1 -1.1 -0.9 -0.6
Eye problems/disorders: Diabetes related eye disease 0.4 0.4 1.0 -1.0 -0.5 -0.1 0.8 -0.8 0.1 -0.6 -0.3
Angina 0.6 0.8 2.4 1.0 1.5 0.2 0.7 0.0 -1.3 -0.8 -0.5
Medication for hormone replacement therapy 1.5 1.7 4.6 1.6 0.5 1.3 0.0 2.1 0.5 -0.5 -1.9
Vitamin and mineral supplements 1.3 1.8 3.5 -1.8 -1.0 -1.1 -1.4 -1.9 -0.2 1.0 1.6
Supplements: Zinc 0.3 0.3 0.5 0.6 0.5 -0.7 0.6 0.7 0.3 -0.4 -0.4
Medication: Co-codamol 1.5 1.8 5.1 0.7 1.0 2.2 0.8 -0.6 -2.2 -0.7 -1.0
Medication: Metformin 0.4 0.5 1.5 0.1 0.5 -0.8 1.2 -0.0 0.1 1.2 0.5
Diabetes (father) 0.9 1.1 2.7 1.5 -0.1 1.6 -0.1 0.7 -1.2 -0.9 -1.2
Diabetes (mother) 0.6 0.8 2.7 -0.1 -0.4 0.1 1.6 0.8 0.2 0.1 1.6
Severe depression (siblings) 0.4 0.4 1.0 0.3 0.4 -0.6 -0.1 0.8 1.0 -0.9 -0.5
Pack years adult smoking proportion 0.2 0.3 1.2 1.1 -0.8 0.1 0.2 -0.3 -0.3 0.4 -0.0
Impedance of leg (right) 0.7 3.4 14.5 1.7 -0.7 3.8 1.1 0.9 -2.2 -1.5 -0.4
Leg fat-free mass (left) 0.6 3.2 10.6 -0.9 1.5 -3.3 0.5 -0.6 1.6 2.4 1.8
Trunk fat percentage 1.2 4.9 9.1 3.0 3.0 2.4 1.0 2.1 -3.0 -1.1 -0.6
Hand grip strength (right) 1.1 2.9 5.8 -1.4 -1.6 -1.0 -0.7 -2.3 0.5 2.4 2.4
Townsend deprivation index at recruitment 0.4 0.6 1.1 -0.1 1.0 -0.8 1.0 0.5 1.1 0.2 -0.6
Current tobacco smoking 0.2 0.4 1.3 0.7 -0.8 0.2 -0.6 -0.4 -0.4 0.1 1.2
Average weekly fortified wine intake 0.3 0.3 0.7 0.0 0.8 -0.7 -0.2 -0.6 -0.2 0.3 0.8
Maternal smoking around birth 0.4 0.6 3.1 0.2 0.6 -1.8 0.3 0.2 1.0 0.4 0.3
Fed-up feelings 0.3 0.5 2.1 -0.4 -0.2 1.0 0.4 -0.2 -0.5 -0.1 -1.4
Frequency of unenthusiasm / disinterest in last 2 weeks 0.2 0.3 1.1 0.8 0.1 0.2 1.1 0.5 -0.1 0.4 0.1
Relative age voice broke 0.3 0.4 0.9 -0.8 -0.5 -0.4 0.5 -0.9 0.7 0.7 0.0
Taking other prescription medications 1.8 2.8 4.5 1.6 1.0 1.3 2.1 1.7 -1.5 -1.9 -2.0
Age when periods started (menarche) 2.1 5.1 11.0 -2.5 -3.3 -2.1 -0.7 -2.0 3.1 0.9 2.0
Bilateral oophorectomy (both ovaries removed) 0.6 0.7 1.5 1.0 0.8 1.2 0.0 -0.1 -1.2 0.9 0.7
Heel bone mineral density (BMD) T-score, automated (left) 0.8 1.8 3.3 -1.0 -1.8 -1.5 -1.0 -1.2 1.3 0.9 1.7
Tinnitus: Yes, but not now, but have in the past 0.4 0.4 1.5 1.2 -0.2 -0.0 -0.5 1.1 -0.1 -0.6 -0.3
Qualifications: CSEs or equivalent 0.7 0.9 3.3 -1.1 -1.8 0.6 0.6 -1.0 -0.7 -0.8 0.0
Serious illness, injury or assault to yourself 1.1 1.3 4.3 0.9 0.7 1.7 2.1 0.3 -1.0 -0.6 -0.8
High blood pressure 0.2 0.5 2.6 0.4 1.6 0.0 0.8 -0.4 -0.5 0.5 0.6
Hayfever, allergic rhinitis or eczema 0.3 0.7 2.3 -0.1 1.1 -1.5 -1.2 -0.2 0.5 0.8 0.3
Multivitamins +/- minerals 0.3 0.4 1.1 0.7 0.1 0.7 -0.2 -0.5 -0.2 -0.7 -1.0
Stomach or abdominal pain in last month 0.7 0.8 3.6 0.3 0.3 0.8 1.0 0.0 -0.5 -1.9 -0.9
Supplements: Glucosamine 0.5 0.6 1.2 0.7 0.3 -0.6 -1.1 1.0 0.7 -0.2 -1.1
Diverticular disease/diverticulitis (self-reported) 0.2 0.2 1.0 -0.3 -0.7 -0.4 -0.0 -0.4 -0.1 0.2 1.0
Medication: Atenolol 0.5 0.7 3.5 0.8 0.6 0.1 -0.6 -0.1 -1.9 -0.7 0.0
Medication: Levothyroxine sodium 0.6 1.0 3.4 0.4 0.5 -0.4 1.2 -0.2 -0.1 1.6 1.9
Sitting height 0.7 4.9 9.4 -0.7 0.6 -3.0 2.4 0.5 3.1 2.1 3.0
Chronic bronchitis/emphysema (father) 1.2 1.5 3.8 1.1 0.9 1.0 0.5 1.2 -1.0 -1.4 -2.0
High blood pressure (mother) 1.2 1.7 4.5 1.9 1.6 0.4 1.5 2.1 -0.0 -0.6 0.3
Body mass index (BMI) 0.5 2.1 4.2 1.7 2.0 0.9 0.3 1.4 -1.9 -1.2 -1.4
Impedance of leg (left) 0.4 2.0 8.6 1.2 -0.7 2.9 1.2 0.6 -1.6 -0.9 0.6
Leg predicted mass (left) 0.6 3.1 10.1 -0.8 1.5 -3.2 0.5 -0.5 1.6 2.3 1.8
Trunk fat mass 0.7 2.8 8.3 2.3 2.9 1.1 1.2 1.5 -2.0 -0.2 0.0
Waist circumference 0.2 0.7 2.9 0.3 1.7 0.3 0.2 -0.3 -1.4 0.4 0.3
Number of incorrect matches in round 0.8 1.2 3.5 -0.6 0.1 0.4 -1.2 -1.6 -1.0 1.9 1.0
Past tobacco smoking 0.7 1.3 4.8 -0.4 -2.2 -1.2 0.4 -0.3 1.8 -0.6 0.5
Alcohol usually taken with meals 1.1 1.8 6.2 1.6 2.5 0.3 -0.5 2.1 -0.3 0.4 -0.1
Nervous feelings 0.4 0.7 3.0 0.4 1.7 -0.3 1.0 0.9 0.9 0.1 -0.3
Frequency of tenseness / restlessness in last 2 weeks 0.8 1.3 5.7 0.1 -1.1 -0.6 1.4 0.4 2.4 0.3 0.7
Hearing difficulty/problems with background noise 0.6 0.9 2.8 -1.7 -1.4 0.0 0.9 -1.2 0.4 -0.3 0.1
Hair/balding pattern: Pattern 2 0.2 0.3 0.6 -0.7 -0.4 -0.5 0.5 0.3 0.8 -0.7 0.5
Had menopause 0.4 0.5 1.3 1.1 -0.3 0.7 0.3 1.0 0.6 0.5 0.2
Had other major operations 0.5 0.6 2.4 0.1 1.5 -1.3 -0.5 -0.3 0.5 -0.1 0.4
Forced vital capacity (FVC) 1.1 4.4 8.9 -2.3 -0.9 -2.9 0.5 -1.3 2.5 1.8 3.0
Heel bone mineral density (BMD) T-score, automated (right) 0.8 1.7 3.5 -1.2 -1.4 -1.9 -0.8 -1.6 1.5 0.7 1.1
Ever unenthusiastic/disinterested for a whole week 1.4 1.7 5.6 1.9 1.5 0.0 -0.0 2.4 0.2 -0.9 -1.3
Qualifications: None of the above 0.4 0.8 3.1 -0.3 -0.3 0.5 -1.0 -1.8 -1.4 0.1 0.2
Financial difficulties in last 2 years 0.4 0.6 2.8 -0.2 1.7 -1.2 0.6 0.2 -0.1 -0.2 -0.1
Mouth/teeth dental problems 0.6 1.0 4.8 -0.8 -0.1 -2.2 0.3 -0.7 0.7 0.3 1.0
Heart attack 0.6 0.8 2.9 0.5 0.3 0.6 0.9 -0.5 -1.7 -0.3 -1.3
Allergy 0.2 0.5 1.8 -0.3 -1.3 0.6 1.3 -0.1 -0.0 -0.0 0.3
Pain all over the body in last month 2.4 2.6 4.4 1.5 1.9 1.7 1.2 1.1 -2.1 -1.5 -1.6
Diabetes (self-reported) 0.1 0.2 0.7 0.3 0.3 -0.7 0.5 -0.2 -0.3 0.8 0.1
Hayfever/allergic rhinitis (self-reported) 1.0 1.3 3.0 -0.9 0.9 -1.7 -0.7 -1.2 0.7 1.4 1.0
Medication: Ramipril 1.0 1.3 4.2 0.8 1.8 0.4 0.9 0.3 -2.0 -0.6 -1.1
Medication: Simvastatin 0.9 1.3 4.0 0.5 2.0 -0.3 1.4 -0.2 -1.6 0.3 1.1
Fluid intelligence score 0.3 0.7 2.2 -0.1 -0.1 -1.5 1.5 0.4 0.9 0.4 0.4
Illnesses of siblings 1.5 2.0 5.3 -1.9 -1.7 -1.3 -0.8 -1.2 2.3 0.6 0.7
Neuroticism score 0.7 1.4 3.6 0.7 0.7 1.2 1.0 1.1 -0.2 -1.6 -1.9
Weight 0.3 1.2 4.4 0.7 2.1 -1.0 1.3 0.6 -0.2 1.1 0.9
Impedance of arm (right) 0.3 1.5 6.1 1.1 0.3 2.5 -0.6 0.7 -1.7 -0.6 0.1
Arm fat percentage (right) 1.2 4.8 9.6 2.4 2.5 2.2 0.3 1.9 -3.1 -2.1 -2.0
Trunk fat-free mass 0.9 5.1 14.3 -1.9 0.4 -3.8 1.4 -1.4 2.3 2.9 2.2
Hip circumference 0.3 1.1 5.4 1.0 2.3 -0.2 1.0 0.8 -1.0 0.3 0.1
Time employed in main current job 0.1 0.2 1.0 0.1 1.0 -0.3 -0.0 0.0 0.1 0.2 0.2
Alcohol intake versus 10 years previously 0.5 0.7 2.3 0.6 -0.8 -1.0 -0.5 0.8 1.5 0.4 -0.4
Father’s age at death 0.9 1.2 5.1 0.5 -0.8 2.3 -0.0 0.5 -0.5 -1.1 -1.4
Worrier / anxious feelings 0.2 0.4 1.4 0.4 1.2 0.2 0.5 0.8 -0.5 -0.9 -0.1
Frequency of tiredness / lethargy in last 2 weeks 0.5 0.8 2.1 -1.1 0.2 -0.8 1.4 -0.8 0.2 1.1 0.7
Falls in the last year 0.7 1.0 3.4 -0.5 1.6 -1.1 0.0 -0.4 0.4 0.7 1.8
Hair/balding pattern: Pattern 3 0.5 0.7 4.1 -0.3 -0.6 -0.6 -2.0 -0.2 0.6 -0.3 -0.3
Number of live births 1.0 1.4 6.0 -0.1 -0.3 -1.8 -0.5 1.1 2.5 0.0 -0.4
Forced expiratory volume in 1-second (FEV1) 1.0 3.5 6.4 -2.3 -1.1 -2.2 0.2 -1.0 2.5 1.7 2.5
Pulse rate 0.6 1.1 6.2 -0.4 -0.7 -0.7 2.5 -0.3 1.0 0.1 0.4
Happiness 2.4 3.0 7.7 2.5 2.5 0.9 1.4 2.8 0.3 -0.1 -0.6
Noisy workplace 1.2 1.5 5.5 -1.3 -2.3 -0.5 -0.5 -1.7 0.2 0.9 0.6
Qualifications: A levels/AS levels or equivalent 0.6 1.3 5.5 -0.1 -0.2 -1.7 0.6 -0.7 0.4 1.0 2.3
Serious illness, injury or assault of a close relative in last 2 years 5.1 5.8 11.2 3.3 1.3 3.0 1.0 3.0 -2.6 -2.0 -2.0
Mouth/teeth dental problems: Dentures 0.2 0.4 2.6 0.3 -0.2 1.6 -0.3 -0.2 -0.6 -0.1 -0.2
Asthma 0.3 0.6 1.6 -0.8 -0.1 -0.7 -1.2 -0.7 1.2 -0.2 -0.1
Medication: Ibuprofen (e.g. Nurofen) 0.3 0.4 1.2 -1.1 0.5 -0.9 -0.3 -0.2 0.6 -0.2 -0.8
Medication: Cholesterol lowering 1.8 2.8 5.4 1.8 2.2 1.1 2.3 1.0 -2.1 -0.6 -1.2
Depression (self-reported) 0.5 0.6 1.1 1.0 1.1 -0.2 1.0 0.9 0.1 -0.5 -0.8
Medication: Lansoprazole 0.3 0.4 1.5 -1.2 -0.3 0.1 0.5 -0.7 -0.1 -0.1 -0.7
Prospective memory result 0.5 0.6 1.8 1.4 0.9 -0.1 -0.6 0.9 0.1 1.0 -0.2
Lung cancer (father) 1.3 1.5 3.5 -1.0 -1.1 -0.9 0.8 -0.8 1.2 1.9 1.6
Illnesses of mother 2.4 3.0 9.5 -2.7 -1.3 0.1 -2.1 -3.1 -0.6 0.5 0.7
Forced expiratory volume in 1-second (FEV1), Best measure 0.9 3.0 5.7 -2.0 -1.9 -2.0 0.5 -0.9 2.4 1.2 2.1
Pulse wave Arterial Stiffness index 0.6 0.8 1.9 -0.5 0.8 -0.4 -1.4 -1.0 -0.8 0.5 1.2
Impedance of arm (left) 0.3 1.3 6.6 0.9 0.2 2.6 -0.3 0.6 -1.4 -0.2 0.4
Arm fat mass (right) 0.6 2.4 5.6 2.0 2.4 0.9 1.0 1.5 -2.0 -0.8 -0.9
Trunk predicted mass 0.8 4.7 13.3 -1.9 0.5 -3.6 1.3 -1.3 2.2 2.9 2.1
Standing height 1.2 11.5 25.4 -2.1 0.4 -4.1 2.3 -1.6 3.5 5.0 5.0
Length of working week for main job 0.3 0.4 1.4 -0.1 -1.2 0.2 0.6 -0.9 -0.6 -0.2 -0.2
Exposure to tobacco smoke at home 0.3 0.4 2.1 -0.5 0.2 -0.6 -0.3 -0.0 1.4 0.5 0.0
Breastfed as a baby 2.2 2.7 7.3 1.4 1.1 2.7 0.8 1.2 -2.3 -0.6 -1.9
Tense / ‘highly strung’ 0.2 0.4 1.0 -0.3 -0.1 -0.7 0.8 -0.0 0.9 -1.0 0.0
Seen doctor (GP) for nerves, anxiety, tension or depression 0.7 1.1 3.7 -0.3 -1.7 -0.4 0.7 -0.3 0.9 -1.9 -0.8
Hair/balding pattern: Pattern 4 0.9 2.3 5.9 1.2 1.8 1.5 2.4 1.8 -1.1 -0.9 -0.7
Birth weight of first child 1.4 2.6 7.8 1.7 1.9 1.2 2.8 1.7 -1.2 -0.4 -0.7
Peak expiratory flow (PEF) 0.9 2.1 5.0 -1.4 0.0 -2.2 0.5 -0.3 2.2 1.2 1.9
Pulse wave reflection index 1.2 1.5 7.0 -0.7 -1.1 0.2 -2.6 -1.2 -0.9 -0.5 0.8
Ever highly irritable/argumentative for 2 days 0.4 0.5 3.0 0.3 0.3 -0.7 -1.7 -0.0 0.5 0.2 -0.0
Loud music exposure frequency 2.5 2.8 7.2 -0.4 -0.4 -2.7 0.4 -0.7 2.6 1.3 2.4
Qualifications: O levels/GCSEs or equivalent 0.4 0.7 2.3 0.5 1.0 -0.1 0.7 1.5 0.1 -0.5 -1.1
Mouth/teeth dental problems: Bleeding gums 0.5 0.6 2.2 0.5 0.7 1.5 0.4 1.1 -0.2 -0.4 -0.6
Blood clot in the leg (DVT) 2.6 3.4 10.8 2.3 3.3 0.8 0.9 2.1 -1.6 -1.2 -1.4
Medication: Paracetamol 0.4 0.6 1.7 -1.3 0.4 -0.9 0.7 -0.6 0.3 0.3 1.1
Headache pain in last month 0.8 1.4 4.4 -1.1 -0.4 -1.2 -1.0 -0.5 2.1 0.7 1.6
Medication for cholesterol, blood pressure or diabetes 0.7 1.1 4.6 -1.1 -2.1 0.4 -1.4 -0.2 1.0 0.1 0.3
Glaucoma (self-reported) 0.5 0.5 1.6 -1.0 -0.7 -0.1 -0.9 -1.2 0.2 0.4 0.4
Gout (self-reported) 0.9 1.2 4.9 -0.6 -0.5 0.3 -0.5 -2.2 -1.3 1.1 1.1
Hypothyroidism/myxoedema (self-reported) 0.5 1.1 3.5 0.2 0.4 -0.4 1.9 -0.1 -0.1 1.5 1.5
Medication: Amlodipine 0.3 0.4 0.8 -0.8 0.6 -0.6 0.2 -0.9 -0.7 -0.3 0.7
Medication: Ventolin 100micrograms inhaler 1.4 1.8 3.0 1.4 0.3 1.7 1.3 1.5 -0.8 -1.7 -1.5
Birth weight 0.7 1.4 3.6 -1.8 -1.4 -0.9 -0.2 -1.9 1.2 -0.5 -0.4
Chronic bronchitis/emphysema (mother) 1.5 1.8 3.4 1.7 1.2 0.8 0.5 1.8 -0.1 -1.8 -1.6
High blood pressure (siblings) 1.4 2.1 5.0 1.6 2.2 1.1 -0.2 0.8 -2.2 -1.0 -1.1
Forced vital capacity (FVC), Best measure 1.4 5.0 10.1 -2.3 -1.4 -3.2 0.5 -1.4 2.7 1.9 3.1
Body fat percentage 1.4 5.6 10.8 3.0 2.8 2.6 1.0 2.1 -3.3 -1.8 -1.3
Leg fat percentage (right) 2.3 8.2 15.2 3.4 2.2 3.7 0.9 2.2 -3.9 -2.9 -2.5
Arm fat-free mass (right) 0.9 4.4 12.3 -1.2 0.8 -3.5 1.8 -0.9 2.1 2.7 2.3
Exposure to tobacco smoke outside home 0.4 0.6 1.9 -1.4 -0.6 -0.3 -0.3 -0.9 0.9 0.8 0.0
Comparative body size at age 10 1.7 4.7 9.8 2.2 1.4 2.1 -1.5 1.1 -3.1 -2.1 -3.0
Number of full brothers 0.4 0.6 2.0 -0.8 0.7 0.1 -0.1 -1.4 -0.7 0.9 0.1
Worry too long after embarrassment 0.5 0.8 2.6 0.4 -0.3 0.9 -0.8 0.2 -0.7 -1.6 -1.2
Seen a psychiatrist for nerves, anxiety, tension or depression 1.0 1.3 4.4 -0.4 0.5 -2.1 1.1 0.6 1.8 -0.9 -0.1
Wheeze or whistling in the chest in last year 0.3 0.6 2.0 -0.0 -0.2 0.3 0.6 0.4 0.6 -1.3 -1.4
Number of children fathered 1.7 1.9 7.4 0.3 -0.5 1.2 -2.7 -0.5 -1.4 -1.6 -1.3
Reason for reducing amount of alcohol drunk: Health precaution 0.8 1.0 3.2 1.2 0.7 0.4 1.0 1.1 -0.3 -0.5 -1.8
Age at first live birth 0.1 0.2 0.6 -0.6 -0.7 -0.3 0.1 -0.4 -0.3 -0.4 -0.4
Pulse wave peak to peak time 0.5 0.6 1.9 0.3 -0.6 0.0 1.4 0.9 1.2 0.1 -0.7
Health satisfaction 0.7 0.9 2.4 1.2 1.5 1.0 0.8 0.7 -0.4 0.2 -1.2
Shortness of breath walking on level ground 0.6 0.7 1.7 0.9 1.2 0.9 0.3 1.0 -0.2 -0.0 -1.3
Qualifications: College or University degree 0.3 1.0 6.4 0.4 0.4 -0.4 -2.5 0.2 0.3 0.4 0.8
Eye problems/disorders: None of the above 2.5 2.9 8.7 -1.3 -0.6 -2.0 0.9 -1.1 1.0 2.4 2.9
Mouth/teeth dental problems: Loose teeth 0.5 0.6 1.6 1.1 0.3 0.4 -0.7 1.0 0.3 0.3 -1.3
Emphysema/chronic bronchitis 0.3 0.3 0.9 0.2 -0.4 0.7 0.9 -0.2 -0.9 -0.1 -0.1
Medication for pain relief, constipation, heartburn 0.4 0.7 1.7 0.5 -0.7 -0.1 -0.1 0.9 1.3 1.0 1.0
Neck or shoulder pain in last month 0.4 0.6 1.9 -0.8 -1.0 0.3 -1.0 -1.4 -0.1 0.1 0.1
Medication: Blood pressure 0.5 0.9 2.1 0.9 1.4 -0.3 1.3 -0.1 -1.1 -0.7 -0.7
Angina (self-reported) 0.6 0.8 2.1 1.1 1.2 0.5 0.4 -0.1 -1.5 -0.9 -0.8
Migraine (self-reported) 1.1 1.4 3.0 -1.4 -1.0 -1.3 0.0 -1.2 1.7 0.2 1.4
Medication: Ibuprofen 0.6 0.7 2.0 -1.4 0.8 -1.3 -0.1 -0.5 0.6 0.1 -0.6
Medication: Allopurinol 0.8 1.0 2.5 -0.3 -1.1 1.2 -0.9 -1.6 -1.3 -0.2 0.1
Medication: Omeprazole 1.5 1.8 3.1 -1.1 0.7 1.8 1.5 -0.9 -1.4 -1.2 -1.7
Medication: Seretide 50 evohaler 0.5 0.6 1.7 1.3 -0.7 1.2 -0.5 0.4 0.2 0.8 -0.0
Mean time to correctly identify matches 0.2 0.4 1.2 -0.4 0.5 -0.2 -0.4 -0.3 1.0 0.5 1.1
Heart disease (mother) 1.5 1.8 5.6 0.7 1.7 -1.4 2.4 1.3 1.1 -0.2 -0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.6 0.7 3.5 -0.2 0.0 -1.9 0.1 0.4 1.2 -0.1 0.7
Whole body fat mass 0.6 2.5 6.7 2.1 2.6 1.0 1.1 1.5 -2.0 -0.6 -0.3
Leg fat mass (right) 0.8 2.9 5.8 2.2 2.4 1.4 1.0 1.6 -2.3 -1.0 -1.0
Arm predicted mass (right) 0.8 4.0 11.0 -1.1 0.9 -3.3 1.7 -0.9 1.9 2.6 2.3
Pulse rate, automated reading 0.3 0.9 6.3 0.5 0.2 -0.1 2.5 0.7 -0.2 -0.4 -0.3
Alcohol intake frequency. 0.6 1.3 2.6 1.6 0.2 1.3 1.4 1.5 0.1 -1.0 -0.9
Comparative height size at age 10 0.6 3.5 8.9 -0.0 1.3 -2.4 1.7 -1.1 1.2 3.0 2.5
Number of full sisters 0.8 1.0 3.1 0.4 1.8 1.5 -0.0 0.3 -1.4 0.3 -0.4
Suffer from ‘nerves’ 0.2 0.3 1.1 0.4 -0.1 0.8 0.5 -0.0 -0.4 -1.0 -0.3
Overall health rating 1.0 2.0 5.4 1.3 0.6 2.3 0.4 0.0 -1.6 -1.4 -2.0
Chest pain or discomfort 0.3 0.5 0.9 -0.9 0.9 -0.6 0.1 -0.9 0.7 0.2 -0.7
Had major operations 0.5 0.6 2.7 -0.3 0.7 0.3 -0.1 -0.5 -1.0 -1.7 -0.7
Age at last live birth 0.5 0.8 2.7 -0.1 -1.4 -0.2 -0.5 0.2 -0.1 -1.6 -1.1
Family relationship satisfaction 0.8 1.0 3.0 1.7 1.1 0.1 1.3 1.1 0.4 0.7 0.4
Leg pain on walking 0.3 0.3 1.1 0.3 -0.1 1.1 0.8 -0.2 -0.2 -0.1 -0.7
Qualifications: NVQ or HND or HNC or equivalent 0.9 1.1 5.9 0.7 -0.0 -0.2 2.4 1.0 0.9 -0.0 -0.4
Commuting to job workplace: Car/motor vehicle 1.8 2.1 5.2 1.2 -0.5 1.8 -0.5 0.5 -1.8 -2.3 -1.7
Illness, injury, bereavement, stress in last 2 years 4.5 5.5 12.4 -2.9 -1.8 -1.9 -2.6 -3.5 1.7 2.1 1.6
Medication: Aspirin 0.6 0.8 2.2 1.2 1.5 -0.5 1.2 0.2 -0.9 -0.1 -0.2
Supplements: Vitamin C 0.7 0.8 3.1 0.2 0.5 -0.3 1.8 1.1 1.2 0.2 0.4
Knee pain experienced in last month 0.4 0.6 2.1 0.2 0.8 -0.7 -0.8 -0.2 0.9 1.4 0.2
Hypertension (Self-reported) 0.2 0.5 2.5 0.5 1.6 0.1 0.9 -0.3 -0.8 0.1 0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.6 1.9 7.1 -0.3 0.2 1.3 2.7 0.3 -0.9 -1.0 -2.1
Illnesses of father: Heart disease 0.8 1.1 3.2 -0.3 1.0 0.5 -0.3 -0.2 -1.8 -0.9 -1.8
Illnesses of siblings: Diabetes 0.6 0.8 2.6 0.8 -0.2 0.2 1.6 1.1 0.8 0.4 0.9
Smoking status: Previous 0.8 1.2 5.9 0.7 2.4 0.6 0.3 0.7 -1.2 0.9 -0.7
Forced expiratory volume in 1-second (FEV1), predicted 2.2 4.6 11.1 -2.2 -1.7 -3.3 -0.5 -1.6 2.7 1.4 2.5
Whole body fat-free mass 0.8 4.8 14.8 -1.4 1.0 -3.8 1.2 -0.9 2.2 2.9 2.3
Leg fat-free mass (right) 0.9 5.0 15.9 -1.4 1.5 -4.0 0.6 -0.9 2.2 2.9 2.4
Arm fat percentage (left) 1.2 4.7 9.1 2.5 2.6 2.4 0.3 1.9 -3.0 -1.8 -1.8
Average weekly red wine intake 0.2 0.3 1.2 -0.1 -1.1 -0.2 -0.4 0.0 0.3 -0.5 -0.6
Handedness (chirality/laterality): Left-handed 0.8 1.0 2.7 -0.1 -0.1 -1.1 -0.5 -1.2 -0.2 1.6 1.6
Mood swings 1.3 2.4 4.5 1.9 0.9 2.1 0.9 1.9 -0.8 -1.2 -2.0
Loneliness, isolation 0.2 0.3 1.5 -0.1 -0.4 -0.3 0.0 -0.0 1.2 0.2 -0.7
Long-standing illness, disability or infirmity 0.2 0.3 1.3 0.2 1.1 0.4 0.5 -0.2 -0.7 -0.4 -0.5
Ever had bowel cancer screening 0.6 0.7 1.2 0.7 1.0 1.0 0.9 0.8 -0.8 -1.1 -0.2
Diabetes diagnosed by doctor 0.2 0.3 1.0 0.5 0.5 -0.6 0.2 0.1 -0.1 1.0 0.0
Ever had stillbirth, spontaneous miscarriage or termination 1.5 1.6 6.3 0.8 0.5 0.7 0.5 1.6 -0.1 -1.5 -2.5
Friendships satisfaction 2.0 2.4 5.5 0.9 1.7 -1.8 0.7 1.7 2.4 1.7 0.8
Qualifications: nursing, teaching 0.5 0.8 2.9 0.8 0.0 0.6 -0.8 0.8 -0.4 -1.7 -1.2
Commuting to job workplace: Walk 4.0 4.3 9.1 -2.2 -0.9 -2.7 0.7 -1.7 2.2 2.2 3.0
Eye problems/disorders: Cataract 2.9 3.4 5.8 2.0 0.9 2.2 0.3 1.9 -1.5 -2.4 -2.3
Mouth/teeth dental problems: Mouth ulcers 0.6 0.9 2.5 0.3 -0.0 1.1 1.2 0.7 -0.9 -0.9 -1.6
Medication for cholesterol 0.2 0.3 0.9 -0.5 -0.4 -0.7 -0.3 -0.4 0.4 0.6 1.0
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.6 1.8 4.1 2.0 0.5 1.7 -0.1 1.5 -1.0 -1.4 -1.4
Back pain experienced in last month 1.0 1.5 4.0 1.2 1.8 1.4 -0.7 0.3 -2.0 -0.0 -0.8
Mineral and other dietary supplements 0.6 0.9 2.3 -0.8 0.0 0.6 0.8 -0.9 -1.4 0.3 1.5
Breast cancer (self-reported) 0.9 1.0 2.6 0.7 0.9 -0.5 1.6 1.6 0.5 -1.0 0.0
Asthma (self-reported) 0.3 0.6 1.5 -0.8 -0.2 -0.7 -1.2 -0.7 1.1 -0.2 -0.1
Osteoporosis (self-reported) 1.8 2.2 5.2 -1.1 1.8 -2.3 1.3 0.4 1.0 1.7 1.4
Osteoarthritis (self-reported) 1.1 1.4 3.6 1.9 1.7 1.4 0.1 0.5 -1.5 0.6 0.0
Medication: Aspirin 0.5 0.7 2.2 0.6 1.4 -0.6 1.5 -0.2 -0.8 0.2 -0.1
Medication: Gliclazide 1.7 1.9 6.5 -0.7 -0.1 -2.1 2.5 -0.2 1.0 1.6 0.7
Illnesses of father: None of the above (group 1) 0.8 1.0 3.1 -0.6 -1.3 -0.9 0.3 -0.5 1.2 0.4 1.8
Smoking status: Current 0.3 0.5 1.4 0.9 -0.4 0.4 -0.8 -0.5 -0.9 0.1 1.2
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.3 0.7 1.8 -1.0 -0.8 -0.8 -0.0 -0.6 0.7 0.4 1.3
Whole body water mass 0.8 4.7 14.4 -1.4 1.0 -3.8 1.1 -1.0 2.2 2.9 2.3
Leg predicted mass (right) 0.9 4.7 14.8 -1.3 1.5 -3.8 0.5 -0.9 2.1 2.8 2.3
Arm fat mass (left) 0.5 1.9 4.8 1.8 2.2 0.9 0.9 1.4 -1.8 -0.6 -0.7
Number of self-reported non-cancer illnesses 0.9 1.6 5.4 1.5 2.3 0.2 1.7 1.3 -0.4 -0.4 -0.5
Average weekly champagne plus white wine intake 0.9 1.2 2.9 0.9 1.1 0.6 -1.7 1.2 -0.5 -0.5 -1.6
Miserableness 1.0 1.7 4.9 0.6 -0.2 1.5 0.9 0.8 -1.0 -2.2 -2.0
Guilty feelings 0.9 1.3 3.5 1.5 1.0 1.1 -1.1 1.9 0.7 0.6 -0.6
Wears glasses or contact lenses 2.1 2.4 6.0 2.3 0.7 1.7 -0.4 2.5 -1.4 -1.3 -0.5
Ever taken oral contraceptive pill 0.5 0.5 2.2 -0.7 -1.5 0.3 -0.1 -0.5 -0.7 -0.6 -0.5
Hearing aid user 0.8 0.9 3.0 0.7 0.6 0.8 1.7 0.4 -1.4 -0.5 -0.4
Mother’s age at death 0.7 0.9 2.8 0.7 -1.3 1.7 0.5 0.4 -0.2 1.1 -0.6
Financial situation satisfaction 1.0 1.3 3.0 1.7 1.3 0.2 1.0 1.7 0.4 0.2 -1.1
Tinnitus: Yes, now most or all of the time 1.1 1.3 4.6 -1.3 -2.1 -0.6 -0.6 -0.8 1.4 -0.1 0.7
Commuting to job workplace: Public transport 0.8 0.9 2.8 -1.0 -0.2 -1.0 0.5 -0.2 1.7 0.9 1.2
Eye problems/disorders: Glaucoma 0.3 0.3 1.0 -0.5 -0.4 1.0 -0.3 -0.9 -0.1 0.4 0.1
Medication: Blood pressure 0.2 0.5 0.7 0.9 0.8 0.8 0.2 0.7 -0.1 -0.7 -0.7
Pain type(s) experienced in last month: Hip pain 0.4 0.5 2.1 -0.5 0.0 0.3 -0.5 -1.4 -0.8 -0.4 0.3
Supplements: Fish oil (including cod liver oil) 1.5 1.9 8.0 -0.1 -1.7 -1.4 -1.1 0.1 2.8 -0.2 -1.0
High cholesterol (Self-reported) 0.6 1.1 2.4 0.7 1.4 0.9 1.5 0.4 -1.4 -1.0 -0.4
Medication: Bendroflumethiazide 1.1 1.7 3.6 -0.5 0.9 -1.9 -0.6 -1.0 1.0 1.8 1.9
Medication: Paracetamol 0.5 0.7 2.3 -1.5 0.4 -0.6 0.5 -1.1 0.2 0.1 1.3
Medication: Lisinopril 0.4 0.5 1.8 -0.3 -0.3 -0.8 1.1 0.2 1.4 -0.1 -0.8
Medication: Atorvastatin 0.4 0.5 1.8 -0.5 -1.2 0.2 0.4 -0.1 0.3 -1.4 -0.7
Illnesses of father: High blood pressure 0.5 0.6 1.2 1.1 -1.0 0.7 -0.3 0.9 0.8 -0.5 -0.4
Alcohol drinker status: Never 0.4 0.4 1.7 0.2 0.3 -0.8 0.5 0.8 1.3 0.4 -0.1
Ever smoked 0.6 1.0 2.8 0.5 1.0 1.7 -0.9 0.1 -1.6 0.6 -0.1
Basal metabolic rate 0.6 3.5 10.3 -0.9 1.3 -3.2 1.3 -0.6 1.6 2.5 2.0
Leg fat percentage (left) 1.6 5.9 11.3 3.0 2.3 3.0 0.8 2.0 -3.4 -2.4 -1.7
Arm fat-free mass (left) 0.6 3.2 9.6 -0.6 1.0 -3.1 1.8 -0.5 1.6 2.3 1.9
Number of operations (self-reported) 0.7 1.1 4.7 0.4 1.5 0.5 0.1 -1.0 -2.2 -0.6 0.2
Average weekly beer plus cider intake 0.5 0.7 2.1 -0.1 -0.1 -1.0 0.4 -0.8 1.2 1.5 0.2
Irritability 1.4 2.3 6.6 1.7 2.6 0.6 1.5 2.2 -0.5 0.0 -0.9
Risk taking 0.5 0.8 2.1 1.0 0.6 -0.3 -0.8 -0.5 -0.8 1.1 1.4
Ever had prostate specific antigen (PSA) test 0.2 0.3 1.5 -0.1 -0.1 0.1 -0.1 -0.2 0.0 -0.8 -1.2
Fractured/broken bones in last 5 years 0.8 1.0 3.7 -0.7 0.0 -1.9 0.4 -0.2 1.9 -0.1 0.4
Age started oral contraceptive pill 0.5 0.7 1.5 0.2 0.6 1.0 -1.2 -0.8 -0.7 0.9 0.7
Diastolic blood pressure, automated reading 1.4 4.4 10.3 2.3 0.9 3.2 -1.1 1.9 -2.4 -2.4 -1.6
Ever depressed for a whole week 0.4 0.5 1.7 0.8 0.4 -0.7 0.5 1.3 0.3 -0.7 0.4
Unable to work because of sickness or disability 1.4 1.8 5.4 1.4 -0.1 1.0 2.3 0.7 -0.4 -1.9 -1.5
Commuting to job workplace: Cycle 0.9 1.1 2.8 0.6 -0.4 1.5 -1.5 0.7 -0.3 -0.7 -1.7
Myopia 0.7 1.0 2.6 0.2 0.6 -0.9 1.3 1.0 0.7 1.1 1.6
Vascular/heart problems diagnosed by doctor 0.3 0.7 3.6 -0.4 -1.9 0.1 -1.2 0.4 0.6 -0.3 -0.3
Cholesterol lowering medication 0.3 0.4 1.8 -0.4 -0.3 -0.6 0.6 -0.8 0.0 0.1 1.3
Medication: Omeprazole (e.g. Zanprol) 1.2 1.5 4.1 -1.5 0.4 1.0 2.0 -1.3 -0.9 -0.8 -1.2
Pain experienced in last month 0.1 0.2 0.7 -0.2 -0.9 -0.7 0.4 0.3 0.5 0.1 0.3
Supplements: Calcium 1.5 1.6 6.1 -1.7 -1.1 -1.1 0.8 -1.0 2.5 0.2 0.4
Basal cell carcinoma (self-reported) 0.5 0.6 1.2 -0.3 0.6 0.8 -0.7 -0.9 -1.0 0.5 1.1
Heart attack/myocardial infarction (self-reported) 0.8 1.0 3.6 0.6 0.4 0.8 1.1 -0.4 -1.9 -0.2 -1.2
Deep venous thrombosis (DVT) (self-reported) 2.0 2.5 7.6 1.8 2.8 0.6 0.8 1.7 -1.2 -1.3 -1.4
Heart disease (siblings) 0.4 0.5 2.3 0.3 -0.1 1.1 0.1 -0.1 -1.5 -0.4 -0.7
Alcohol drinker status: Previous 2.1 2.4 6.9 1.6 1.1 2.6 1.5 1.0 -2.0 -0.6 -1.0
Pack years of smoking 0.2 0.3 1.1 1.1 -0.5 0.3 0.4 -0.3 -0.6 0.4 -0.2
Impedance of whole body 0.3 1.6 8.0 1.1 -0.3 2.8 0.3 0.6 -1.6 -0.7 0.4
Leg fat mass (left) 0.6 2.5 6.2 2.1 2.5 1.0 0.8 1.5 -2.0 -0.7 -0.5
Arm predicted mass (left) 0.7 3.5 10.7 -0.8 1.0 -3.3 1.4 -0.7 1.6 2.4 2.1