TWAS hub - FMN1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Breast Mammary Tissue	0.2240	0.0710	3.2e-03	0.016	NA	0.041	NA	0.027	4.7e-02	NA	3.7e-03	NA	1.5e-02
2	GTEx	Esophagus Mucosa	0.1410	0.0510	3.7e-03	0.173	NA	0.170	NA	0.172	1.1e-11	NA	1.9e-11	NA	1.3e-11
3	GTEx	Skin Sun Exposed Lower leg	0.1560	0.0520	1.6e-03	0.066	NA	0.068	NA	0.066	3.6e-06	NA	2.7e-06	NA	3.7e-06
4	GTEx	Testis	0.2840	0.0850	7.0e-04	0.021	NA	0.030	NA	0.034	3.9e-02	NA	1.7e-02	NA	1.2e-02
5	GTEx	Thyroid	0.3860	0.0530	4.9e-14	0.199	NA	0.226	NA	0.236	3.6e-15	NA	2.9e-17	NA	4.9e-18
6	GTEx	Whole Blood	0.0890	0.0340	7.2e-03	0.037	NA	0.042	NA	0.039	2.4e-04	NA	9.2e-05	NA	1.5e-04
7	METSIM	Adipose	0.1238	0.0275	1.0e-09	0.122	0.076	0.113	0.116	0.117	8.1e-18	1.7e-11	1.8e-16	5.9e-17	4.9e-17
8	NTR	Blood	0.3325	0.0280	0.0e+00	0.419	0.369	0.426	0.423	0.425	9.3e-149	1.2e-126	4.0e-152	1.2e-150	1.5e-151
9	TCGA	Head and Neck Squamous Cell Carcinoma	0.0455	0.0204	7.2e-03	0.045	0.019	0.045	NA	0.040	7.1e-06	3.0e-03	8.4e-06	NA	2.5e-05
10	TCGA	Kidney Renal Clear Cell Carcinoma	0.0430	0.0202	8.7e-03	0.013	0.021	0.000	NA	0.004	1.2e-02	1.6e-03	3.6e-01	NA	1.1e-01
11	TCGA	Lung Adenocarcinoma	0.0593	0.0218	8.4e-04	0.014	0.031	0.012	NA	0.018	8.5e-03	1.3e-04	1.3e-02	NA	3.2e-03
12	TCGA	Prostate Adenocarcinoma	0.1416	0.0342	2.2e-10	0.107	0.115	0.072	NA	0.102	2.8e-11	5.4e-12	5.4e-08	NA	8.2e-11
13	TCGA	Thyroid Carcinoma	0.1770	0.0410	8.7e-10	0.070	0.121	0.104	NA	0.106	2.2e-07	8.5e-12	2.6e-10	NA	1.8e-10

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13
Prostate Cancer	5.3	7.4	14.4	-0.6	-3.8	-2.6	-0.6	-3.7	-3.5	-1.3	-1.2	-3.8	-2.5	-1.8	-3.6	-3.0
Myopia	4.0	5.8	14.7	0.9	2.6	3.8	-0.8	1.4	2.8	3.6	3.5	2.6	0.6	-2.3	1.9	0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	3.9	4.6	11.9	0.3	-2.4	-1.0	-1.4	-2.8	-1.1	-0.1	0.3	-2.3	-3.4	-2.7	-2.9	-2.9
Ever had bowel cancer screening	3.5	4.1	12.8	2.0	-1.9	-0.3	0.5	-2.0	-3.1	0.1	0.5	-2.0	-1.2	-3.6	-2.4	-2.9
Pulse wave reflection index	3.0	3.7	8.9	-0.5	-2.7	-1.3	-0.4	-3.0	-1.7	-1.1	-1.2	-2.8	-2.2	-2.3	-1.7	-1.6
Verbal and Numeric Reasoning (VNR)	2.8	6.7	14.3	-1.8	3.8	2.7	0.4	3.4	1.6	1.5	1.0	3.7	3.2	1.7	3.5	2.4
Average weekly fortified wine intake	2.7	3.1	6.2	0.6	2.2	1.9	0.5	2.5	1.8	0.9	0.6	2.3	2.2	1.6	2.4	1.7
Hair/balding pattern: Pattern 4	2.4	5.8	11.3	1.7	3.4	2.9	1.3	2.6	2.3	2.1	2.5	3.3	1.5	-0.7	3.1	2.2
Age at first live birth	2.4	4.2	9.8	0.3	3.1	2.1	-0.4	1.9	2.1	1.1	1.1	3.0	2.0	1.2	3.1	2.3
Lung cancer (father)	2.3	2.6	7.3	-1.1	-2.2	-2.7	1.2	-0.9	-1.5	-1.9	-2.0	-2.3	-0.5	1.0	-1.3	-0.5
Eye problems/disorders: Diabetes related eye disease	2.1	2.3	4.5	-1.8	-1.8	-1.3	-0.1	-1.9	-0.3	-0.9	-1.0	-1.6	-2.0	-1.0	-2.1	-1.8
Medication: Ibuprofen (e.g. Nurofen)	2.1	2.6	5.2	-2.3	-1.3	-2.2	-0.1	-2.2	-1.2	-1.6	-1.9	-1.3	-1.9	0.6	-1.9	-0.5
Supplements: Vitamin C	2.1	2.4	5.2	1.3	-2.0	-0.1	-0.6	-2.3	-1.7	-0.0	0.3	-2.0	-1.7	-1.9	-1.6	-2.1
Ever smoked	2.1	3.7	8.8	-0.3	2.4	2.0	1.2	2.7	1.0	1.4	1.1	2.3	1.5	1.9	2.4	3.0
Osteoarthritis (self-reported)	2.0	2.6	7.5	0.5	-1.4	-0.3	-1.5	-2.6	-1.5	0.7	0.9	-1.3	-2.4	-2.7	-1.1	-1.5
Neck or shoulder pain in last month	1.9	2.7	7.4	1.5	-0.0	1.3	0.4	-1.1	-0.6	2.6	2.7	0.1	-2.0	-2.4	-1.2	-1.9
Medication: Ibuprofen	1.9	2.2	4.2	-2.0	-1.1	-2.0	-0.3	-1.8	-0.9	-1.6	-1.9	-1.1	-1.6	1.2	-1.9	-0.4
Ever taken oral contraceptive pill	1.9	2.1	4.5	-0.9	1.9	0.9	0.4	1.7	1.4	0.7	0.5	2.0	1.0	1.8	2.0	2.1
Intelligence (Savage-Jansen 2018)	1.8	5.5	11.8	-1.3	3.4	2.6	-0.4	2.8	2.7	1.2	0.6	3.4	2.5	1.5	3.1	2.2
Age at last live birth	1.8	2.6	7.5	0.3	2.0	2.7	0.7	0.6	0.8	2.7	2.7	2.0	0.4	-0.3	1.3	0.8
Qualifications: College or University degree	1.7	5.2	12.2	-1.2	2.9	0.3	-0.7	2.6	2.4	-0.4	-0.7	2.8	3.0	3.1	3.5	2.4
Overall health rating	1.7	3.6	9.1	0.9	-2.5	-1.6	1.6	-2.7	-1.2	0.6	0.9	-2.4	-2.7	-0.3	-3.0	-1.5
Alcohol drinker status: Never	1.7	2.0	6.1	1.5	-1.5	-1.7	-0.4	-1.5	-0.0	-1.3	-1.6	-1.6	-1.2	0.4	-2.5	-1.2
Age at First Birth	1.6	2.3	9.8	-2.3	2.0	1.2	-0.2	1.0	3.1	1.1	0.8	2.0	0.5	0.7	0.9	1.2
Medication: Omeprazole	1.6	1.9	4.7	-0.8	-1.3	-0.8	0.1	-2.2	-1.0	-1.0	-1.0	-1.3	-1.8	-1.8	-1.6	-1.7
Neuroticism (2016)	1.5	2.2	4.1	-0.2	1.3	1.5	0.8	1.3	1.7	1.9	1.8	1.5	1.9	0.2	2.0	1.4
Medication: Co-codamol	1.5	1.8	6.9	0.5	-1.2	-2.2	-0.7	-0.5	-2.6	-1.4	-1.5	-1.1	0.3	-0.4	-0.6	-1.6
Fluid intelligence score	1.5	3.1	8.7	-1.6	3.0	2.6	-0.9	1.3	1.1	0.9	0.7	2.8	1.1	0.0	2.6	1.2
Medication: Lansoprazole	1.5	1.7	4.9	-0.3	-0.1	1.4	-0.5	-1.6	1.1	1.8	1.9	-0.2	-2.0	-2.2	-0.4	-0.7
Long-standing illness, disability or infirmity	1.5	2.3	5.3	1.4	-2.3	-2.0	-0.4	-2.1	-1.7	-0.6	-0.8	-2.1	-1.5	-0.5	-1.6	-1.0
Commuting to job workplace: Walk	1.5	1.6	4.1	-1.1	-1.6	-1.2	0.0	-1.9	0.1	-0.3	-0.6	-1.6	-1.5	-1.1	-2.0	-1.3
Miserableness	1.5	2.6	5.5	-1.2	1.7	1.5	0.7	2.0	0.4	1.7	2.0	1.9	2.4	0.4	2.1	1.4
Mother’s age at death	1.5	1.9	4.6	1.8	1.5	1.4	-0.9	1.3	1.5	1.2	1.3	1.6	1.3	-0.4	2.1	-0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	1.4	1.8	4.5	-0.4	2.0	0.9	0.2	1.8	0.9	1.1	0.9	2.1	1.6	1.1	1.4	1.6
Commuting to job workplace: Cycle	1.4	1.7	5.3	-1.4	0.4	-0.1	0.0	1.4	1.2	-1.0	-1.0	0.4	2.0	2.3	1.4	1.6
Alzheimer’s Disease (in mother)	1.3	1.5	3.4	1.8	-0.8	-1.2	1.5	-1.3	-0.7	-1.6	-1.6	-1.1	-1.1	0.1	-1.3	-1.1
Hearing difficulty/problems: Yes	1.3	2.0	4.2	1.9	-1.7	-1.4	-0.8	-2.0	-1.3	0.3	0.5	-1.6	-1.6	-1.1	-1.6	-1.1
Qualifications: CSEs or equivalent	1.3	1.8	5.2	0.4	-0.5	-1.4	0.1	1.2	-0.8	-2.3	-2.3	-0.4	1.5	2.2	-0.1	0.9
Had other major operations	1.3	1.6	4.8	0.0	1.7	1.1	-0.2	1.8	0.5	0.8	0.4	1.7	1.1	1.2	1.5	2.2
Mouth/teeth dental problems: Bleeding gums	1.3	1.7	6.7	-1.4	-0.8	-1.2	2.6	0.3	-0.1	-1.4	-1.4	-0.8	0.2	2.6	-0.1	0.6
Vitamin and mineral supplements	1.2	1.6	2.9	-0.9	1.7	0.9	1.2	1.2	1.2	1.6	1.6	1.7	0.6	0.5	1.3	1.4
Past tobacco smoking	1.2	2.2	5.8	-0.4	-1.7	-1.7	-1.3	-2.0	0.4	-1.3	-1.2	-1.6	-0.8	-0.7	-2.0	-2.4
Nervous feelings	1.2	2.2	6.7	-2.0	-1.1	0.4	0.2	-1.5	-0.9	0.5	1.0	-1.0	-2.1	-2.6	-1.9	-1.5
Alcohol intake versus 10 years previously	1.2	1.7	4.4	0.4	-0.7	-0.4	-1.1	-2.1	-1.2	0.8	0.6	-0.7	-2.0	-1.4	-1.9	-1.9
Pulse wave peak to peak time	1.2	1.4	4.0	-2.0	1.7	0.1	-0.8	1.6	1.3	0.1	0.4	1.7	1.0	0.7	0.9	1.1
Alcohol intake frequency.	1.2	2.7	6.1	2.4	-2.1	-1.9	0.1	-2.5	-0.5	-0.3	-0.3	-1.9	-1.9	-0.8	-1.9	-2.0
Blood Red Count	1.1	10.4	38.4	1.4	3.3	6.2	0.2	3.2	2.1	4.9	5.0	3.3	1.6	-1.3	1.6	1.6
Stomach or abdominal pain in last month	1.1	1.3	4.6	0.3	-1.2	-0.1	0.2	-1.6	-0.8	0.5	0.7	-1.1	-1.3	-2.1	-1.4	-1.6
Medication: Ramipril	1.1	1.4	3.8	-0.2	-1.1	0.3	0.9	-1.5	-1.2	1.1	1.3	-1.2	-1.6	-1.0	-1.9	-0.7
Osteoporosis (self-reported)	1.1	1.4	4.2	2.1	0.9	1.8	0.4	0.3	1.9	1.5	1.4	0.9	-0.6	-0.4	0.1	-0.2
Wears glasses or contact lenses	1.1	1.3	3.5	0.2	1.9	1.5	0.3	1.5	1.3	0.7	0.7	1.6	1.5	0.8	0.8	0.7
Hearing aid user	1.1	1.3	3.2	-0.2	1.7	1.5	1.3	0.8	1.0	1.5	1.5	1.8	-0.1	-0.2	0.2	-0.5
Supplements: Fish oil (including cod liver oil)	1.1	1.4	3.8	0.4	-1.3	-0.2	-0.3	-1.5	-1.9	-0.4	-0.2	-1.4	-0.8	-1.8	-1.5	-1.5
Medication: Bendroflumethiazide	1.1	1.7	3.7	-0.0	-1.9	-1.6	0.9	-1.0	-0.7	-1.9	-1.7	-1.8	-0.5	-0.6	-1.4	-0.9
Medication: Atorvastatin	1.1	1.4	3.3	0.3	-1.8	-1.1	0.3	-1.6	-1.6	-0.6	-0.3	-1.8	-0.9	-0.1	-1.3	-1.5
Average weekly beer plus cider intake	1.1	1.7	6.4	0.0	0.8	2.5	1.2	0.7	0.4	2.2	2.4	0.8	0.5	-0.9	-0.2	0.5
Relative age voice broke	1.0	1.6	4.2	-1.4	-1.4	-0.9	-0.2	-1.9	-0.7	-0.2	-0.3	-1.4	-2.1	-0.6	-2.0	-1.1
Medication: Atenolol	1.0	1.3	3.8	-1.9	-1.4	-1.2	0.6	-1.3	-0.9	0.3	0.3	-1.4	-0.7	-0.9	-0.7	-1.6
Sitting height	1.0	7.3	18.1	-3.5	2.9	0.8	-0.4	3.4	3.0	-0.9	-1.2	2.7	4.3	3.0	3.0	2.8
Medication: Simvastatin	1.0	1.5	4.7	0.7	1.5	2.2	0.3	0.6	1.1	1.5	1.5	1.4	0.0	-1.8	0.6	-0.1
Blood clot in the leg (DVT)	1.0	1.3	4.5	1.1	1.1	1.2	0.7	0.6	0.4	1.6	1.6	1.2	0.8	-0.2	2.1	0.3
Forced expiratory volume in 1-second (FEV1), predicted	1.0	2.1	7.6	-2.8	1.2	0.0	-1.2	0.9	2.1	0.2	-0.1	1.3	1.5	1.3	1.3	1.9
Average weekly champagne plus white wine intake	1.0	1.3	4.2	-0.8	1.6	0.7	-0.2	1.6	2.0	0.2	-0.2	1.4	1.4	1.1	0.9	0.8
Tinnitus: Yes, now most or all of the time	1.0	1.1	3.1	0.2	-0.7	0.6	1.8	-0.7	-1.7	1.2	1.7	-0.7	-0.4	-1.1	-0.6	-0.9
Eye problems/disorders: Glaucoma	1.0	1.2	6.1	0.6	-1.2	-1.0	2.5	-1.4	-0.7	-0.2	-0.1	-1.3	-0.7	0.3	-0.8	-1.0
Illnesses of father: High blood pressure	1.0	1.2	2.4	-1.4	-1.2	-1.6	1.3	-1.4	-1.0	-1.2	-1.0	-1.1	-1.1	0.1	-0.7	-0.6
Heart disease (siblings)	1.0	1.2	3.1	-0.5	-0.8	-1.8	1.0	0.3	-1.0	-1.4	-1.2	-0.6	1.6	1.2	1.1	-0.3
Schizophrenia vs Biploar Disorder	0.9	1.2	2.5	-0.7	0.4	-0.8	-1.0	1.2	0.1	-1.2	-1.4	0.3	1.6	1.5	0.9	1.4
Bipolar Disorder (2011)	0.9	0.9	4.5	0.2	-0.0	1.0	2.1	-0.4	0.8	0.8	0.7	-0.1	-1.4	0.6	-1.2	-0.0
Lung FVC	0.9	4.8	12.5	-2.8	-2.3	-2.9	0.6	-1.8	-2.0	-3.5	-3.3	-2.4	-1.4	-0.2	-1.4	-0.3
High blood pressure (mother)	0.9	1.2	4.1	0.2	-0.9	-1.3	0.3	-0.5	-0.5	-1.9	-2.0	-1.0	-1.2	1.1	-1.2	-0.4
Alcohol usually taken with meals	0.9	1.4	5.9	0.6	0.2	-1.6	0.7	-0.0	-0.2	-2.4	-2.4	-0.1	0.1	1.8	0.4	0.3
Hayfever/allergic rhinitis (self-reported)	0.9	1.2	3.2	1.1	1.0	1.4	0.4	1.8	1.7	0.6	0.8	1.0	1.5	-0.0	1.2	0.5
Illnesses of siblings	0.9	1.2	7.5	0.9	1.0	0.8	-2.7	0.7	2.0	0.2	-0.2	0.9	0.5	-0.4	-0.1	0.3
Hair/balding pattern: Pattern 3	0.9	1.4	3.4	0.2	1.3	1.5	1.5	1.8	1.3	0.4	0.5	1.3	1.1	1.1	1.4	0.5
Medication: Cholesterol lowering	0.9	1.5	4.0	1.1	1.2	1.8	-0.1	1.0	0.6	1.8	2.0	1.2	0.4	-1.0	1.3	0.1
Depression (self-reported)	0.9	1.1	2.2	0.2	1.4	1.0	-0.1	1.1	0.9	0.9	0.8	1.5	1.2	0.5	1.4	1.2
Gout (self-reported)	0.9	1.2	8.2	1.0	-0.9	-1.3	-2.9	-0.8	-0.6	-0.4	-0.3	-0.8	-1.4	-0.3	-0.8	-0.1
Mouth/teeth dental problems: Loose teeth	0.9	1.1	3.9	0.9	0.6	1.1	-0.1	0.2	1.6	2.0	1.8	0.7	-0.7	0.3	-0.7	-0.6
Medication for pain relief, constipation, heartburn	0.9	1.6	5.6	0.6	1.4	1.6	-0.1	2.4	0.8	0.7	0.6	1.4	1.4	0.6	1.5	1.4
Number of full sisters	0.9	1.1	2.5	-0.6	-0.7	-0.1	-0.4	-1.2	-1.5	1.3	1.2	-0.7	-1.0	-0.6	-1.6	-1.4
Illness, injury, bereavement, stress in last 2 years	0.9	1.1	2.9	-1.3	1.7	1.4	1.0	0.8	1.0	0.8	0.8	1.4	-0.3	-0.0	1.2	0.2
Illnesses of father: Heart disease	0.9	1.3	3.5	0.2	0.7	-0.5	1.4	0.6	0.8	-0.7	-1.0	0.8	1.5	1.9	1.4	1.8
Smoking status: Previous	0.9	1.4	3.2	0.2	0.9	1.4	1.8	1.6	-0.5	1.2	1.4	0.9	0.5	-0.2	1.5	1.6
Irritability	0.9	1.4	5.0	0.1	-0.3	1.0	-0.9	-0.6	-0.4	1.8	1.8	-0.1	-1.5	-2.2	-1.2	-1.0
Medication: Omeprazole (e.g. Zanprol)	0.9	1.1	2.9	-1.0	-0.7	-0.3	0.2	-1.6	-1.1	-0.2	-0.1	-0.8	-1.3	-1.7	-1.1	-1.4
Deep venous thrombosis (DVT) (self-reported)	0.9	1.2	3.8	1.5	0.9	1.1	0.4	0.5	0.4	1.6	1.6	1.0	0.8	-0.5	2.0	0.1
Alzheimer’s Disease (in father)	0.8	0.9	3.3	0.6	0.5	1.8	-0.4	0.5	1.8	1.2	1.2	0.6	-0.3	-0.3	0.5	0.3
Alzheimer’s Disease (including proxy)	0.8	1.2	4.1	1.6	-1.1	-0.2	0.3	-1.4	0.2	-0.2	-0.2	-1.1	-2.0	-0.9	-1.4	-1.1
Other serious medical condition/disability diagnosed by doctor	0.8	1.0	5.3	1.3	-0.4	0.1	-2.3	-0.4	-0.5	-0.7	-1.4	-0.4	-1.2	-0.4	-1.1	-0.6
Angina	0.8	1.1	3.1	0.9	-1.0	-0.2	-0.4	-1.4	-1.1	0.3	0.2	-0.9	-1.2	-1.7	-1.8	-1.0
Fed-up feelings	0.8	1.4	5.9	-0.1	0.7	1.3	1.2	0.7	0.3	2.1	2.4	0.9	1.5	-0.3	0.8	0.3
Qualifications: None of the above	0.8	1.7	5.5	-0.2	-0.2	1.4	2.3	-0.2	0.9	1.8	2.1	-0.3	-1.2	-1.6	-1.2	-0.7
Happiness	0.8	0.9	3.8	-1.0	0.2	1.2	0.9	-0.5	0.4	2.0	1.9	0.3	-0.9	-0.4	0.1	0.1
Mouth/teeth dental problems: Dentures	0.8	1.3	3.7	0.6	-0.3	1.0	1.9	-0.7	-0.1	1.7	1.8	-0.2	-0.5	-1.9	0.0	-1.4
Pulse wave Arterial Stiffness index	0.8	0.9	3.2	1.8	-1.4	0.2	0.7	-1.3	-0.9	0.2	-0.1	-1.4	-0.8	-0.5	-0.7	-0.9
High blood pressure (siblings)	0.8	1.1	4.8	-1.4	-1.0	-0.8	2.2	-1.1	-1.3	-0.3	0.1	-0.9	-1.0	1.0	-0.2	-0.3
Average weekly red wine intake	0.8	1.2	3.7	0.0	1.3	0.7	-0.6	1.2	1.9	0.4	0.5	1.0	0.7	0.8	1.7	1.4
Qualifications: nursing, teaching	0.8	1.2	8.5	0.4	1.2	-0.1	-2.9	0.3	1.0	-1.0	-1.0	1.2	0.2	0.6	0.6	0.3
Fractured/broken bones in last 5 years	0.8	1.0	4.4	-0.9	0.9	0.7	-0.5	0.7	0.4	-0.4	-0.4	1.1	2.1	-0.8	2.0	0.3
Supplements: Calcium	0.8	0.9	2.6	-0.7	0.6	0.1	1.3	0.5	1.2	0.7	0.6	0.7	1.5	1.1	1.6	0.6
Neuroticism (Nagel 2018)	0.7	1.6	5.8	-0.0	0.6	1.5	0.9	0.1	0.9	2.1	2.4	0.8	0.6	-2.0	1.2	0.2
Lupus	0.7	1.1	2.4	0.5	1.0	1.5	-1.5	0.7	-0.8	0.9	1.0	1.1	1.1	-0.9	1.3	0.8
Allergy or Eczema	0.7	1.7	4.1	-0.6	1.5	1.6	-0.2	1.7	1.5	0.2	0.2	1.5	2.0	0.2	1.4	1.9
Type 2 Diabetes (T2D) (2018)	0.7	1.3	5.6	-1.5	-0.2	0.6	-1.6	-1.0	-0.0	1.1	0.9	-0.2	-1.4	-2.4	-0.4	-0.6
Medication for hormone replacement therapy	0.7	0.8	2.3	-0.5	-1.4	-0.8	-0.7	-1.5	-1.1	0.4	-0.0	-1.3	-0.6	0.0	-0.7	-0.7
Medication: Metformin	0.7	1.0	3.0	-1.0	0.7	1.3	-0.8	-0.1	1.0	1.4	1.3	0.8	-0.7	-1.7	0.4	0.3
Townsend deprivation index at recruitment	0.7	0.9	6.2	0.1	-0.6	-0.6	1.3	-1.0	-0.8	0.0	0.1	-0.7	-1.0	0.3	-2.5	-0.6
Age when periods started (menarche)	0.7	1.7	3.8	-0.2	-1.5	0.4	1.7	-1.9	0.3	0.8	1.1	-1.5	-1.3	-1.9	-1.1	-1.4
Supplements: Glucosamine	0.7	0.9	2.4	0.1	1.2	0.5	0.7	0.9	0.2	-0.4	-0.4	1.2	1.1	0.8	1.5	1.4
Hearing difficulty/problems with background noise	0.7	1.1	2.8	1.0	-1.7	-1.5	-0.7	-0.9	0.4	0.5	0.6	-1.6	-0.3	-0.5	-1.4	-1.1
Impedance of arm (right)	0.7	3.1	13.7	-1.4	0.5	1.7	-1.1	0.1	1.8	2.6	2.6	0.7	-0.3	-3.7	-1.0	-1.4
Serious illness, injury or assault of a close relative in last 2 years	0.7	0.8	7.0	-0.6	-0.4	0.1	-2.6	0.2	-1.1	-0.1	-0.3	-0.2	1.0	-0.4	0.2	-0.0
Exposure to tobacco smoke at home	0.7	0.8	2.6	-0.3	-0.4	0.2	-0.3	-0.8	-0.2	1.0	1.0	-0.4	-1.6	-1.1	-1.4	-1.2
Glaucoma (self-reported)	0.7	0.9	2.2	0.5	-1.0	-0.2	1.2	-1.5	-0.9	0.7	0.5	-0.9	-1.5	-0.1	-0.8	-1.0
Chronic bronchitis/emphysema (mother)	0.7	0.8	3.8	0.6	-0.5	0.5	1.9	-0.5	-0.1	1.4	1.4	-0.5	0.4	-0.8	0.1	0.6
Health satisfaction	0.7	0.9	4.5	0.3	-1.4	-2.1	0.2	-1.5	-0.2	-0.5	-0.7	-1.3	-0.4	0.7	-0.3	-0.4
Shortness of breath walking on level ground	0.7	0.9	4.3	0.4	-0.8	-1.9	0.0	0.0	-0.6	-0.8	-0.9	-0.7	0.1	2.1	-0.0	0.5
Emphysema/chronic bronchitis	0.7	0.8	3.9	-0.0	-0.8	-0.1	0.5	-0.8	-1.4	0.2	0.6	-0.9	-0.8	-2.0	-0.8	-0.7
Angina (self-reported)	0.7	0.9	3.0	1.1	-0.9	-0.4	-0.6	-1.3	-0.9	0.1	-0.1	-0.8	-1.0	-1.3	-1.7	-0.9
Medication: Allopurinol	0.7	0.9	4.4	1.0	-1.1	-1.5	-2.1	-0.9	-0.4	-0.3	-0.2	-1.0	-0.4	-0.3	-0.2	-0.2
Suffer from ‘nerves’	0.7	1.1	3.6	-1.0	-0.9	0.0	-0.1	-1.6	-0.5	-0.1	-0.1	-0.8	-1.6	-1.1	-1.9	-1.3
Leg pain on walking	0.7	0.8	2.5	-0.9	-0.9	-1.3	1.6	-0.8	0.8	-1.2	-1.0	-0.7	-1.0	0.3	-0.4	0.1
Loneliness, isolation	0.7	1.0	3.1	-0.1	-0.5	0.4	1.2	0.4	0.3	1.8	1.7	-0.5	1.2	1.0	0.3	1.4
Diabetes diagnosed by doctor	0.7	1.1	5.8	-0.5	-0.1	0.9	-0.5	-1.1	-0.2	1.1	1.1	0.0	-1.8	-2.4	-0.5	-0.4
Mouth/teeth dental problems: Mouth ulcers	0.7	1.2	4.0	1.1	1.2	2.0	-0.7	0.3	1.1	1.2	1.2	1.2	-0.3	-1.3	0.8	-0.1
Number of self-reported non-cancer illnesses	0.7	1.1	3.5	1.5	0.9	1.0	0.4	0.1	1.2	1.8	1.9	1.2	-0.7	0.5	0.2	0.4
High cholesterol (Self-reported)	0.7	1.2	4.3	0.8	0.1	1.5	0.1	-0.9	-0.1	1.9	2.1	0.1	-1.1	-1.6	-0.4	-0.7
Depressed Affect (Nagel 2018)	0.6	1.3	4.2	-0.3	0.3	1.0	1.5	0.5	-0.5	1.5	2.0	0.5	1.6	-1.1	1.5	0.9
Coronary Artery Disease (CAD)	0.6	0.7	3.1	-1.8	0.3	0.3	0.8	-0.1	1.4	0.6	0.7	0.2	0.5	0.8	0.4	1.2
Rheumatoid Arthritis	0.6	0.8	3.0	-0.8	1.1	1.7	0.3	0.7	0.2	0.8	0.6	1.1	-1.0	0.7	-0.3	1.0
Schizophrenia (2014)	0.6	1.4	6.4	0.7	-1.0	-1.1	1.3	0.7	-1.2	-1.1	-1.2	-1.0	1.3	2.5	0.0	0.2
Average weekly spirits intake	0.6	0.8	2.7	0.5	1.0	0.4	-0.3	1.7	0.2	-0.5	-0.5	1.1	1.2	0.7	1.4	0.3
Sensitivity / hurt feelings	0.6	1.0	4.4	0.1	0.4	0.8	1.5	0.4	1.1	2.0	2.1	0.6	-0.2	0.1	0.4	0.1
Diabetes (father)	0.6	0.8	1.7	1.0	-0.5	-0.6	-1.1	-0.2	-1.2	-1.0	-1.1	-0.5	0.1	-0.8	-0.8	-1.3
Leg fat-free mass (left)	0.6	3.0	14.1	-1.0	1.5	0.4	0.5	1.6	2.0	0.2	0.1	1.6	1.9	3.8	1.4	2.6
Maternal smoking around birth	0.6	0.8	2.3	-0.1	-1.1	-1.0	-0.6	-0.7	-1.0	-0.4	-0.7	-1.2	-0.7	1.5	-1.4	-0.2
Mouth/teeth dental problems	0.6	0.9	4.9	-0.0	-0.5	-1.3	-2.2	-0.5	-1.1	-1.1	-1.2	-0.6	-0.1	0.0	-0.4	0.4
Heart attack	0.6	0.8	2.8	1.0	-0.2	0.2	1.4	-0.6	-0.1	1.5	1.7	-0.2	-0.2	-1.4	0.0	-0.3
Impedance of arm (left)	0.6	2.8	14.0	-1.9	0.1	1.5	-0.4	0.0	1.8	2.2	2.2	0.4	-0.4	-3.7	-0.9	-1.4
Length of working week for main job	0.6	0.6	1.9	-0.8	0.7	-0.5	-0.6	0.5	0.5	-1.4	-1.4	0.5	1.0	0.7	0.5	0.4
Loud music exposure frequency	0.6	0.6	1.8	-1.1	0.5	0.2	-0.4	0.8	1.1	-0.4	-0.7	0.4	0.7	1.1	-0.0	1.3
Medication: Amlodipine	0.6	0.9	6.4	-0.6	0.2	0.5	2.5	-0.6	1.3	-0.1	-0.0	0.2	-1.3	-0.2	-0.8	0.3
Exposure to tobacco smoke outside home	0.6	0.8	2.3	0.7	-0.9	-0.9	0.8	-0.9	-0.3	-1.1	-1.0	-1.0	-1.1	0.3	-1.5	-0.4
Number of full brothers	0.6	0.7	2.5	-1.6	-0.4	0.6	1.3	-0.0	0.6	1.5	1.1	-0.4	0.8	-0.2	-0.5	0.2
Wheeze or whistling in the chest in last year	0.6	1.1	2.6	0.9	-1.4	-1.3	0.3	-0.9	-1.6	-1.5	-1.2	-1.5	-0.4	-0.1	-0.7	-0.2
Number of children fathered	0.6	0.7	1.8	1.3	0.0	1.1	0.4	-0.0	-0.8	1.2	1.2	0.0	-0.7	-1.3	0.5	-0.6
Chest pain or discomfort	0.6	0.8	2.8	0.4	-1.7	-1.4	0.0	-0.6	-0.8	-0.8	-0.6	-1.6	-0.2	-0.1	-1.0	0.2
Mood swings	0.6	1.2	3.1	0.5	0.8	1.1	0.6	1.5	-0.3	1.1	1.5	1.0	1.8	-0.7	1.4	0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.6	1.3	3.8	-1.5	-1.2	-1.4	0.7	-0.7	0.4	-1.9	-1.9	-1.2	-0.7	0.2	-0.8	-0.5
Ever had prostate specific antigen (PSA) test	0.6	0.7	2.5	1.2	0.6	0.3	0.3	1.6	0.7	0.5	0.6	0.7	1.2	0.8	0.8	0.3
Unable to work because of sickness or disability	0.6	0.8	3.8	-0.7	-0.8	-0.2	2.0	-0.9	1.4	0.4	0.5	-0.6	-0.8	0.6	-0.9	-0.0
Basal cell carcinoma (self-reported)	0.6	0.8	3.3	-0.3	-0.1	-0.5	-0.9	0.4	-1.0	-1.8	-1.8	-0.0	0.6	-0.8	-0.0	-0.5
Heart attack/myocardial infarction (self-reported)	0.6	0.8	2.7	0.5	-0.2	0.2	1.5	-0.6	-0.3	1.5	1.6	-0.2	0.0	-1.6	0.3	-0.5
Depression (Nagel 2018)	0.5	0.8	1.6	-1.3	0.8	0.6	-1.2	0.1	0.7	1.0	0.9	0.9	1.2	-0.1	1.2	0.8
Schizophrenia (2018)	0.5	1.0	3.2	1.8	-1.3	-0.6	1.4	0.4	-1.3	-0.2	-0.1	-1.3	0.2	1.6	-0.4	-0.1
Crohns Disease (2017)	0.5	1.1	3.0	0.3	1.0	0.7	0.7	1.6	1.2	0.3	0.1	0.9	1.6	1.7	0.7	1.1
Ovarian Cancer	0.5	0.7	2.2	0.3	0.6	1.5	0.4	0.3	1.4	1.0	1.1	0.7	0.4	-0.2	1.0	0.7
HbA1C	0.5	0.5	1.5	0.8	-0.6	-0.5	0.0	-1.2	-0.5	-0.5	-0.4	-0.7	-0.8	-0.7	-0.7	-1.1
Chronotype (morning person)	0.5	1.2	5.8	-1.5	-0.4	-0.4	2.4	0.7	0.2	-0.7	-0.6	-0.2	1.0	1.8	0.8	0.9
Relative age of first facial hair	0.5	1.0	1.9	-1.4	-1.2	-0.8	-0.5	-1.2	-1.3	-0.8	-0.9	-1.2	-1.1	-0.7	-0.7	-0.7
Ever had hysterectomy (womb removed)	0.5	0.6	3.5	0.8	-0.9	-0.9	1.9	0.2	0.0	-0.0	0.2	-0.8	-0.4	0.3	0.5	-0.6
Diabetes (mother)	0.5	0.7	2.4	0.4	0.6	0.7	-0.4	0.8	0.9	1.2	1.1	0.7	0.1	0.2	0.6	1.6
Taking other prescription medications	0.5	0.8	2.7	1.3	-0.1	0.4	-0.0	-0.6	-0.5	0.9	0.9	0.1	-1.6	-1.2	-1.0	-0.9
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.2	3.6	-1.9	-0.0	-1.0	-0.7	0.5	1.1	-1.6	-1.5	-0.2	1.1	1.6	0.2	0.5
Serious illness, injury or assault to yourself	0.5	0.7	2.7	1.6	-0.5	-0.4	-0.1	-0.8	-0.7	0.5	0.5	-0.5	-1.2	-1.0	-0.7	-0.6
Leg predicted mass (left)	0.5	2.8	13.7	-1.0	1.5	0.4	0.5	1.5	1.9	0.2	0.1	1.5	1.8	3.7	1.2	2.5
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.7	2.9	-0.2	0.5	0.9	0.5	0.4	1.7	1.5	1.5	0.7	0.5	0.1	0.1	-0.2
Hair/balding pattern: Pattern 2	0.5	0.7	4.2	-0.1	0.5	0.4	-2.1	-0.3	0.3	0.4	0.2	0.6	0.2	-1.6	-0.3	-0.8
Had menopause	0.5	0.6	4.4	0.9	-0.5	0.0	2.1	0.3	0.4	0.6	0.7	-0.4	0.8	0.3	-0.1	-0.9
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	1.6	0.7	-0.3	-0.6	-0.6	-0.6	0.0	1.3	1.2	-0.2	-1.1	0.6	-1.2	0.0
Diabetes (self-reported)	0.5	0.7	1.8	0.8	0.7	1.3	-0.3	-0.0	0.8	1.1	1.1	0.7	-1.0	-1.3	0.2	0.4
Time employed in main current job	0.5	0.6	1.5	0.6	-0.1	-1.2	-1.1	-0.1	0.8	-1.2	-1.1	-0.1	0.7	-0.2	0.8	0.1
Father’s age at death	0.5	0.6	2.1	-0.2	1.1	0.4	-0.3	1.1	1.4	0.2	0.1	1.3	0.7	0.8	0.5	0.4
Number of live births	0.5	0.7	4.5	-0.2	-0.1	-0.2	1.2	0.8	0.8	0.6	0.5	-0.1	2.1	0.7	0.7	-0.2
Pulse rate	0.5	0.8	2.2	1.4	0.6	0.1	1.5	0.9	0.8	-0.3	-0.4	0.6	0.9	0.8	1.1	0.9
Asthma	0.5	0.9	2.8	1.7	-0.4	-0.5	-0.8	-0.7	-0.9	-1.0	-1.1	-0.3	-1.6	0.4	-1.4	-0.2
Headache pain in last month	0.5	0.9	2.5	-1.4	-0.7	0.4	0.5	-1.3	-0.4	0.7	0.9	-0.6	-1.0	-1.6	-0.7	-1.2
Birth weight	0.5	1.0	4.0	-1.6	0.7	1.3	-2.0	0.8	0.6	0.9	1.0	0.7	0.4	-0.7	-0.2	-0.6
Forced vital capacity (FVC), Best measure	0.5	1.9	11.8	-3.4	-0.5	-1.1	0.8	-0.5	0.5	-1.8	-2.0	-0.6	-0.6	1.3	-0.7	0.2
Handedness (chirality/laterality): Left-handed	0.5	0.6	2.0	-0.8	0.2	-0.2	1.4	0.6	0.8	-0.8	-0.9	0.0	0.8	1.3	-0.2	0.3
Asthma (self-reported)	0.5	1.0	2.8	1.4	-0.5	-0.6	-1.0	-0.8	-0.9	-1.2	-1.3	-0.3	-1.7	0.2	-1.4	-0.3
Number of operations (self-reported)	0.5	0.8	3.3	1.8	-0.4	-0.6	-1.5	-0.2	-0.6	-0.4	-0.5	-0.4	-0.8	-0.4	-1.2	-0.9
Cholesterol lowering medication	0.5	0.8	3.7	0.7	-0.5	0.1	0.3	-1.2	-0.5	0.2	0.4	-0.5	-0.8	-1.9	-1.1	-1.0
Pain experienced in last month	0.5	0.8	3.1	1.2	0.6	-0.7	-1.2	0.9	0.1	-0.8	-1.2	0.5	0.2	1.8	0.0	0.5
Pack years of smoking	0.5	0.8	3.0	-0.4	0.5	1.1	1.6	0.7	0.5	1.5	1.7	0.5	0.0	0.0	-0.1	-0.2
Bipolar Disorder (2018)	0.4	0.7	1.5	-1.2	-1.2	-0.3	0.8	-1.1	-0.3	0.6	0.7	-1.0	-0.6	0.2	-0.7	-1.1
Bipolar Disorder or Schizophrenia	0.4	1.1	3.2	0.7	-1.8	-0.6	1.6	-0.4	-1.2	0.2	0.3	-1.6	-0.3	1.3	-0.7	-0.8
Worry (Nagel 2018)	0.4	0.9	4.1	-0.6	0.1	0.6	0.0	-0.9	1.4	1.0	1.2	0.2	-1.0	-2.0	-0.5	-0.7
Breast Cancer	0.4	1.0	3.1	0.9	0.5	-0.7	-0.1	0.7	-0.4	-1.6	-1.4	0.4	1.3	1.8	1.0	0.8
Triglycerides	0.4	0.6	1.9	0.1	-1.3	-0.6	0.1	-0.6	-0.9	-0.8	-0.7	-1.4	-0.4	-0.7	-0.7	-0.3
Lung FEV1/FVC ratio	0.4	1.8	4.8	1.3	1.2	1.5	-1.8	0.7	0.9	2.2	2.0	1.4	0.6	-0.2	1.3	0.5
Hand grip strength (left)	0.4	1.1	2.7	-0.6	-1.0	-1.0	-0.2	-1.1	-1.0	-1.1	-1.3	-1.1	-1.0	1.6	-0.7	-0.8
Frequency of depressed mood in last 2 weeks	0.4	0.5	1.3	-0.1	0.8	0.5	-0.3	0.7	0.4	1.1	1.1	1.0	0.7	-0.0	0.7	0.8
Severe depression (siblings)	0.4	0.4	2.8	1.7	-0.3	-0.2	-0.5	0.1	0.2	-0.6	-0.5	-0.3	0.1	0.2	1.2	0.1
Pack years adult smoking proportion	0.4	0.7	2.2	-1.2	0.3	0.9	1.3	0.5	0.5	1.3	1.5	0.3	-0.0	0.1	-0.2	-0.3
Current tobacco smoking	0.4	0.7	5.8	0.7	0.1	0.1	-2.4	-0.3	-0.1	-0.1	-0.6	0.2	-1.2	0.1	-0.6	-0.2
Tinnitus: Yes, but not now, but have in the past	0.4	0.4	1.1	-0.0	-1.1	-0.9	-0.6	-0.5	0.1	-0.8	-0.8	-1.0	-0.3	0.3	-0.5	-0.1
High blood pressure	0.4	1.0	3.2	0.6	-1.1	-1.8	1.1	-1.2	0.4	-0.6	-0.4	-0.9	-1.1	0.8	-1.4	0.4
Diverticular disease/diverticulitis (self-reported)	0.4	0.4	1.4	-1.2	0.5	0.5	1.0	0.3	-0.6	0.7	0.7	0.5	-0.1	-0.1	0.0	1.1
Impedance of leg (left)	0.4	1.8	11.6	-0.5	-1.0	-0.1	-1.2	-0.9	-0.4	-0.2	-0.2	-1.1	-1.0	-3.4	-1.2	-2.2
Forced vital capacity (FVC)	0.4	1.7	8.1	-2.8	-0.1	-0.6	1.1	-0.0	0.6	-2.0	-2.1	-0.3	-0.3	1.3	-0.5	1.0
Heel bone mineral density (BMD) T-score, automated (right)	0.4	1.0	4.2	-2.1	0.5	-0.4	-0.1	0.8	1.1	-0.8	-0.8	0.3	1.3	1.5	0.5	0.8
Trunk fat-free mass	0.4	2.3	13.3	-0.0	1.4	0.4	-0.1	1.2	1.2	-0.0	-0.2	1.2	1.4	3.6	1.4	2.3
Worrier / anxious feelings	0.4	0.8	2.7	-1.6	-0.3	-0.4	0.4	-1.0	1.7	0.8	0.9	-0.3	0.0	-0.8	-0.6	-1.1
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.7	3.1	0.4	0.6	0.5	0.1	0.4	0.6	1.7	1.8	0.8	-0.1	0.7	0.1	1.0
Qualifications: A levels/AS levels or equivalent	0.4	1.0	2.2	0.1	1.5	0.6	-1.1	1.0	0.8	-0.4	-0.7	1.4	0.7	1.0	1.2	1.5
Prospective memory result	0.4	0.5	1.2	0.7	0.7	0.1	0.9	1.1	1.0	0.3	-0.1	0.8	0.4	0.9	0.5	0.3
Illnesses of mother	0.4	0.4	1.9	-1.4	-0.1	-0.0	-1.1	0.0	-0.5	-0.4	-0.3	-0.1	1.0	-0.6	0.8	0.2
Trunk predicted mass	0.4	2.2	13.3	-0.0	1.4	0.4	-0.1	1.2	1.1	-0.1	-0.2	1.2	1.4	3.6	1.5	2.3
Standing height	0.4	4.3	10.7	-2.2	2.6	2.4	-0.3	2.0	3.3	1.9	1.6	2.5	1.7	1.7	1.6	1.8
Breastfed as a baby	0.4	0.5	1.3	-0.0	0.7	0.2	-0.5	1.1	1.0	0.9	0.9	0.8	0.5	0.1	0.7	0.2
Birth weight of first child	0.4	0.7	3.1	-0.2	-0.6	-0.5	-0.5	-1.0	0.1	-0.3	-0.3	-0.6	-1.0	-0.5	-1.3	-1.8
Arm fat-free mass (right)	0.4	1.9	13.0	0.0	0.7	-0.2	0.4	0.9	0.8	-1.0	-1.1	0.6	1.2	3.6	1.1	1.9
Comparative body size at age 10	0.4	1.2	2.9	-1.1	-0.7	-1.4	-1.7	-0.1	0.2	-1.6	-1.5	-0.7	0.8	1.5	0.3	0.5
Migraine (self-reported)	0.4	0.5	4.5	-0.7	0.4	-0.4	-0.3	0.5	-0.5	-0.0	-0.3	0.2	0.2	2.1	-0.4	0.3
Medication: Seretide 50 evohaler	0.4	0.5	1.7	0.7	0.1	0.7	0.6	0.6	0.4	1.3	1.2	0.1	0.3	0.6	0.0	0.6
Arm predicted mass (right)	0.4	2.1	14.8	-0.1	1.0	-0.1	0.5	1.1	0.9	-0.7	-0.9	0.8	1.3	3.8	1.1	2.1
Knee pain experienced in last month	0.4	0.6	2.5	-1.6	-0.8	-1.1	0.1	-0.3	1.1	-0.8	-0.5	-0.7	0.5	0.3	0.0	-0.0
Hypertension (Self-reported)	0.4	1.0	3.0	0.8	-1.1	-1.4	1.2	-1.4	0.5	0.1	0.3	-0.9	-1.4	0.4	-1.7	-0.1
Illnesses of siblings: Diabetes	0.4	0.5	1.9	0.7	0.5	0.5	0.5	0.7	-0.7	-0.2	0.1	0.6	0.2	-0.1	1.2	1.4
Whole body fat-free mass	0.4	2.4	13.9	-0.5	1.4	0.3	0.2	1.3	1.5	-0.1	-0.2	1.3	1.5	3.7	1.4	2.4
Leg fat-free mass (right)	0.4	2.1	10.3	-1.0	1.2	0.4	0.6	1.2	1.8	0.2	0.1	1.2	1.3	3.2	1.0	2.2
Friendships satisfaction	0.4	0.6	2.4	1.6	-0.1	0.5	0.5	-0.3	-0.4	0.9	1.2	0.0	-1.3	-0.0	-0.2	-0.2
Eye problems/disorders: Cataract	0.4	0.5	2.5	-0.3	0.2	-0.3	-1.4	-0.0	-0.5	0.1	0.1	0.3	-0.5	-1.6	-0.2	-0.6
Back pain experienced in last month	0.4	0.6	2.0	-0.0	-1.4	-1.0	0.1	-0.7	-1.3	-1.0	-0.9	-1.2	-0.3	-0.1	0.1	0.6
Illnesses of father: None of the above (group 1)	0.4	0.5	1.3	0.2	0.7	0.5	-0.7	1.1	0.8	0.8	0.8	0.5	0.7	-0.3	0.9	0.5
Whole body water mass	0.4	2.4	13.3	-0.5	1.4	0.4	0.3	1.3	1.4	-0.1	-0.2	1.3	1.5	3.7	1.4	2.4
Leg predicted mass (right)	0.4	2.1	10.3	-1.0	1.3	0.5	0.6	1.3	1.7	0.3	0.2	1.3	1.4	3.2	1.0	2.2
Financial situation satisfaction	0.4	0.4	2.0	-0.3	0.5	-0.1	1.2	0.4	1.4	0.6	0.4	0.6	0.2	0.3	0.5	0.7
Medication: Blood pressure	0.4	0.7	2.8	1.7	-0.0	-1.1	0.5	0.2	0.9	-0.6	-0.5	0.1	0.5	1.1	-0.5	1.2
Basal metabolic rate	0.4	2.2	12.5	-0.6	1.2	0.1	0.3	1.2	1.4	-0.2	-0.3	1.1	1.6	3.5	1.2	2.3
Risk taking	0.4	0.6	3.5	0.3	-0.0	-1.0	-0.4	0.3	-0.1	-0.8	-1.0	-0.0	0.8	1.9	0.4	0.8
Age started oral contraceptive pill	0.4	0.5	1.7	0.4	0.4	0.9	0.5	-0.2	0.7	1.2	1.3	0.5	-0.3	-1.0	0.1	-0.1
Ever depressed for a whole week	0.4	0.6	1.9	0.9	-0.5	-0.7	-0.7	-0.4	-0.8	-0.6	-0.7	-0.6	-0.9	0.8	-1.4	-0.2
Impedance of whole body	0.4	2.3	14.7	-1.2	-0.3	1.0	-1.0	-0.5	0.9	1.5	1.4	-0.2	-0.8	-3.8	-1.3	-2.0
Body Mass Index (BMI) (2010)	0.3	0.4	1.6	1.3	-0.2	-0.1	-1.1	0.0	-0.3	-1.2	-0.9	-0.2	-0.2	-0.5	0.1	-0.0
Fasting Glucose	0.3	0.4	1.7	0.2	-0.1	0.2	-1.3	0.3	-1.3	-0.6	-0.1	0.1	0.4	-1.0	0.2	-0.2
Heel T-Score	0.3	2.2	8.2	-2.9	-1.4	-1.8	1.6	-1.3	-0.3	-1.8	-1.5	-1.4	-0.8	-0.9	-1.0	-1.2
Height	0.3	4.8	10.8	-0.6	2.2	1.6	1.9	2.6	3.3	1.1	1.2	2.2	2.4	3.1	2.0	2.7
Systolic Blood Pressure	0.3	1.4	11.5	-0.6	-0.4	-0.6	3.4	-0.6	1.1	-0.4	-0.0	-0.5	-0.6	1.0	-1.5	-0.4
Smoking Status	0.3	0.8	3.7	-0.7	-0.1	0.1	-1.0	-0.2	-1.6	-0.2	-0.5	-0.0	-1.4	-1.9	-0.3	-0.2
Respiratory disease	0.3	0.7	1.5	0.9	0.7	0.5	-0.4	1.0	0.5	-1.2	-1.2	0.8	0.6	1.2	0.5	1.0
Systolic blood pressure, automated reading	0.3	1.0	5.7	1.0	-1.0	-1.1	2.4	-0.8	-0.1	-0.4	0.1	-0.9	-0.6	0.5	-1.0	-0.6
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.5	1.7	-1.3	-0.3	-0.7	0.1	-0.4	0.6	0.8	0.7	-0.2	0.3	1.1	0.4	0.8
Bilateral oophorectomy (both ovaries removed)	0.3	0.4	1.2	0.8	-1.0	-0.5	-0.4	-0.4	-0.1	0.3	0.4	-1.1	-0.2	-0.3	-0.4	-1.0
Hayfever, allergic rhinitis or eczema	0.3	0.6	2.7	-0.4	0.7	1.0	-0.3	1.0	0.6	-0.1	0.1	0.7	1.6	-0.6	0.9	0.8
Neuroticism score	0.3	0.5	2.4	-0.9	0.2	0.3	0.9	0.3	0.7	1.4	1.6	0.3	0.2	-0.5	-0.3	-0.1
Weight	0.3	1.4	7.1	-0.5	0.8	-0.5	0.6	1.0	1.2	-0.2	-0.2	0.8	1.5	2.7	0.8	1.9
Falls in the last year	0.3	0.4	1.0	-0.8	-0.7	0.0	0.0	-0.2	1.0	0.9	0.8	-0.5	-0.7	0.2	-0.9	-0.0
Forced expiratory volume in 1-second (FEV1)	0.3	1.0	3.4	-1.9	0.5	-0.1	0.6	0.4	1.1	-1.4	-1.5	0.4	0.0	1.4	0.0	1.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	1.0	5.9	-2.4	0.1	-0.6	0.2	0.0	0.9	-1.3	-1.5	0.1	-0.0	1.5	-0.1	0.6
Ever highly irritable/argumentative for 2 days	0.3	0.3	0.9	0.1	-0.3	-0.7	-0.9	-0.4	0.9	0.3	0.1	-0.2	-0.1	0.8	-0.9	-0.3
Qualifications: O levels/GCSEs or equivalent	0.3	0.4	1.6	-0.0	0.3	0.9	1.2	0.6	1.1	0.1	0.1	0.3	0.3	0.7	0.6	0.7
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	2.3	-0.3	0.5	0.2	0.3	0.9	0.7	-0.6	-0.8	0.4	1.5	0.4	0.8	0.5
Worry too long after embarrassment	0.3	0.5	1.6	-0.3	0.7	0.9	0.7	0.3	1.1	1.2	1.1	0.6	-0.1	-0.3	-0.1	0.0
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.4	1.4	-0.1	0.2	-0.2	-1.0	0.4	-0.7	-0.3	-0.5	0.1	0.7	0.8	-0.1	1.2
Medication: Blood pressure	0.3	0.5	1.5	-0.9	-0.5	-0.3	0.3	-1.0	-0.4	0.7	1.1	-0.3	-1.2	-0.0	-0.6	0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.4	2.2	1.5	-0.3	0.1	-0.5	-0.4	0.2	-0.5	-0.4	-0.1	-0.3	-1.1	0.1	-0.6
Leg fat mass (right)	0.3	1.0	4.2	-0.4	-0.1	-1.5	0.6	0.6	0.6	-0.9	-0.7	-0.1	1.4	2.1	0.5	1.3
Had major operations	0.3	0.4	1.6	1.0	0.4	0.4	0.3	0.6	-0.1	-1.3	-0.8	0.5	0.2	0.1	-0.4	0.3
Commuting to job workplace: Car/motor vehicle	0.3	0.3	1.2	0.9	-0.0	0.6	-0.7	0.3	-1.0	0.1	0.3	-0.2	0.3	-1.1	0.3	-0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.4	1.4	0.7	-0.0	0.3	0.0	-0.2	0.4	1.1	1.2	0.1	0.7	0.1	0.8	0.4
Medication: Gliclazide	0.3	0.3	2.7	-0.6	-0.2	-0.7	-1.6	-0.1	0.3	-0.4	-0.6	0.0	-0.4	-0.4	0.2	0.2
Smoking status: Current	0.3	0.5	3.6	0.8	-0.1	-0.1	-1.9	-0.5	-0.5	-0.2	-0.7	0.1	-1.1	0.0	-0.4	-0.2
Commuting to job workplace: Public transport	0.3	0.4	0.9	-0.7	0.3	0.7	1.0	0.5	0.8	0.6	0.5	0.4	-0.1	0.9	-0.3	0.2
Arm fat-free mass (left)	0.3	1.4	10.5	0.1	0.7	-0.2	0.2	0.7	0.6	-0.7	-0.8	0.5	1.1	3.2	0.9	1.8
Vascular/heart problems diagnosed by doctor	0.3	0.8	2.3	-0.5	1.0	1.4	-1.5	0.9	-0.2	0.0	-0.2	0.8	0.7	-0.7	1.2	-0.7
Arm predicted mass (left)	0.3	1.4	10.7	0.1	0.7	-0.3	0.0	0.6	0.4	-0.8	-0.9	0.5	1.1	3.3	0.8	1.8
Irritable Bowel Disease (IBD)	0.2	0.4	1.7	-0.2	0.3	0.4	1.2	0.5	-0.4	0.4	0.2	-0.0	0.8	1.3	0.1	0.4
Ulcerative Colitis (UC)	0.2	0.4	2.7	-0.1	-0.0	0.1	1.6	-0.1	-1.5	0.1	0.2	-0.3	0.1	0.8	-0.1	0.2
Major Depression (MDD)	0.2	0.2	0.6	-0.2	0.6	-0.7	-0.5	0.2	-0.3	0.1	0.1	0.8	0.8	0.5	0.7	0.2
Reaction Time	0.2	0.3	1.0	-0.6	-0.3	-0.3	0.1	0.3	1.0	-0.9	-0.7	-0.2	0.6	0.4	0.1	0.3
Crohns Disease (2012)	0.2	0.3	1.6	0.0	0.4	0.6	-0.3	0.6	1.3	0.7	0.3	0.1	-0.2	0.7	-0.6	0.4
Mean Putamen Volume	0.2	0.3	0.8	0.4	0.4	0.4	-0.9	-0.1	-0.3	0.7	0.7	0.5	-0.3	-0.9	0.1	-0.1
HDL Cholesterol	0.2	0.3	1.0	-0.9	0.4	0.7	0.4	0.3	-0.4	0.8	1.0	0.4	-0.2	0.1	-0.1	0.0
Primary Biliary Cirrhosis	0.2	0.3	1.0	0.5	0.2	-0.3	0.4	1.0	-0.3	-0.7	-0.3	0.1	0.4	0.8	-0.3	-0.6
Type 2 Diabetes (T2D) (2012)	0.2	0.2	1.2	-0.4	-0.6	-1.1	0.5	-0.6	-0.0	-0.4	-0.3	-0.6	0.1	-0.1	-0.2	-0.1
Ulcerative Colitis	0.2	0.2	1.0	0.4	0.2	-0.1	-0.0	0.2	-0.9	-0.3	-0.3	-0.0	0.9	1.0	0.3	0.4
Blood Platelet Count	0.2	2.6	8.0	-1.4	-1.8	-2.3	0.3	-1.6	-0.2	-2.8	-2.8	-1.7	-0.4	-0.5	-1.3	-0.3
Blood White Count	0.2	1.7	11.2	0.5	-1.1	-0.4	-0.8	-1.5	-0.6	-0.1	0.3	-1.0	-1.2	-3.3	-1.0	-1.6
BMI	0.2	1.2	5.3	-0.1	-0.7	-2.3	0.4	-0.2	-0.1	-1.6	-1.7	-0.6	0.8	1.6	0.4	0.6
Waist Hip Ratio (WHR)	0.2	0.9	3.3	-0.1	0.8	1.0	-0.2	1.1	1.2	1.2	1.2	0.8	0.7	-1.8	-0.0	-0.2
Hypothyroidism (self reported)	0.2	0.6	2.2	1.2	0.2	0.8	1.5	0.9	0.4	-0.4	-0.3	0.5	0.5	0.9	0.7	0.2
Neuroticism	0.2	0.4	1.3	-0.4	-0.0	0.3	1.0	-0.1	0.3	1.0	1.1	-0.0	0.2	-1.2	-0.3	-0.6
Ever used hormone-replacement therapy (HRT)	0.2	0.3	0.9	0.2	-1.0	-0.7	0.2	-0.6	-0.0	0.4	0.3	-1.0	0.2	-0.4	-0.3	-0.8
Supplements: Zinc	0.2	0.2	0.7	0.8	-0.3	-0.4	-0.7	0.3	0.4	-0.1	0.2	-0.1	0.5	-0.2	0.8	0.6
Impedance of leg (right)	0.2	0.9	6.2	-0.8	-0.6	-0.0	-1.3	-0.4	0.0	-0.2	-0.3	-0.5	-0.3	-2.5	-0.7	-1.4
Hand grip strength (right)	0.2	0.5	4.1	-0.5	-0.4	-0.5	-0.1	-0.3	-0.1	-0.6	-0.8	-0.4	-0.4	2.0	0.1	-0.2
Multivitamins +/- minerals	0.2	0.3	1.1	0.2	-0.3	-0.3	-0.8	-0.0	-0.5	-0.9	-1.0	-0.3	0.4	0.7	-0.3	-0.1
Medication: Levothyroxine sodium	0.2	0.3	1.4	0.3	-1.2	-0.0	0.3	-0.4	-0.3	0.2	0.1	-1.0	-0.5	0.2	-0.6	0.1
Chronic bronchitis/emphysema (father)	0.2	0.2	0.9	-0.2	-0.3	0.1	0.3	-0.4	-0.9	-0.3	-0.1	-0.1	-0.9	-0.1	-0.5	-0.2
Body mass index (BMI)	0.2	0.9	4.0	0.5	-0.4	-1.7	0.7	0.1	-0.3	-1.1	-0.9	-0.4	0.7	2.0	0.1	1.2
Number of incorrect matches in round	0.2	0.3	1.1	1.0	0.2	-0.4	1.1	0.1	-0.6	0.4	0.4	0.4	-0.2	0.5	0.9	-0.1
Financial difficulties in last 2 years	0.2	0.2	0.7	0.6	-0.6	-0.7	-0.7	-0.2	-0.5	0.4	0.3	-0.3	0.0	-0.0	-0.8	-0.1
Pain all over the body in last month	0.2	0.2	1.7	-0.1	-0.2	-0.3	0.5	-0.6	0.2	0.0	-0.2	-0.2	0.1	0.2	-0.1	1.3
Hip circumference	0.2	0.7	2.8	-0.6	-0.3	-1.2	1.4	-0.4	0.6	-0.6	-0.6	-0.3	0.8	1.7	-0.1	0.6
Tense / ‘highly strung’	0.2	0.3	1.7	-0.5	1.0	0.1	-0.1	0.7	1.3	0.0	-0.1	1.0	-0.0	0.2	-0.2	0.3
Peak expiratory flow (PEF)	0.2	0.4	1.2	0.2	0.4	0.2	-0.7	0.4	-0.4	-1.1	-1.1	0.4	0.3	0.6	0.3	0.7
Leg fat percentage (right)	0.2	0.6	3.9	-0.3	-0.7	-2.0	0.5	0.1	-0.2	-1.0	-0.7	-0.6	1.0	0.8	-0.0	0.4
Mean time to correctly identify matches	0.2	0.3	1.0	0.6	-0.1	0.6	1.0	0.7	0.7	0.2	0.6	-0.1	0.9	-0.1	0.5	0.2
Pulse rate, automated reading	0.2	0.7	2.0	1.4	0.7	0.8	1.0	0.4	0.8	0.9	1.2	0.8	-0.2	-0.9	0.4	0.0
Family relationship satisfaction	0.2	0.2	0.9	-0.2	-0.4	-0.6	-0.1	-0.8	-0.8	-0.3	-0.2	-0.2	-1.0	0.3	0.0	-0.2
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.3	1.5	-1.2	0.2	0.5	-0.0	0.6	-0.5	0.7	0.5	0.2	0.5	-0.0	0.3	-0.0
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.3	0.6	-0.1	0.4	0.2	-0.8	-0.5	0.4	-0.5	-0.7	0.7	-0.2	0.7	-0.3	0.6
Medication for cholesterol	0.2	0.4	1.8	-1.3	0.6	0.7	-0.9	0.7	0.0	0.1	0.0	0.6	0.1	-0.5	0.5	-0.1
Breast cancer (self-reported)	0.2	0.3	1.0	-0.0	0.0	-0.3	0.3	-1.0	-0.2	0.8	0.8	0.2	-1.0	-0.0	-0.2	-0.6
Pain type(s) experienced in last month: Hip pain	0.2	0.3	0.8	-0.8	-0.8	-0.4	0.2	-0.9	0.5	0.4	0.4	-0.8	0.0	0.0	0.0	0.1
Medication: Lisinopril	0.2	0.3	1.0	-0.4	-0.8	-1.0	-0.6	-0.8	-0.3	0.2	0.1	-0.7	-0.8	-0.3	-0.2	0.1
Leg fat percentage (left)	0.2	0.8	4.8	-0.2	-1.1	-2.2	0.7	-0.4	-0.6	-1.1	-0.8	-1.0	0.4	0.2	-0.5	-0.1
Diastolic blood pressure, automated reading	0.2	0.8	2.5	0.0	-0.9	-1.3	1.6	-0.7	-0.3	-0.9	-0.3	-0.8	-1.1	0.2	-1.1	0.3
Alcohol drinker status: Previous	0.2	0.3	1.0	1.0	-0.6	-0.4	1.0	-0.1	-0.5	0.4	0.4	-0.7	-0.2	0.1	0.0	-0.3
Leg fat mass (left)	0.2	0.7	2.7	-0.2	-0.4	-1.7	0.6	0.2	0.4	-0.9	-0.7	-0.3	1.0	1.6	0.1	0.9
LDL Cholesterol	0.1	0.1	0.4	-0.0	0.4	-0.4	0.1	0.2	0.5	-0.4	-0.6	0.5	-0.4	-0.2	-0.2	-0.0
Cardiovascular Disease	0.1	0.5	2.0	0.6	-0.4	-1.0	0.8	-0.8	0.5	-0.2	-0.1	-0.2	-1.4	0.5	-0.7	0.4
Hair Pigment	0.1	1.8	4.6	-1.5	0.2	-1.2	-0.3	0.8	1.7	-1.2	-1.2	0.2	1.7	2.1	1.8	1.7
Tanning	0.1	0.7	1.8	-0.4	0.7	1.1	-0.5	1.3	0.6	1.4	1.0	0.6	1.2	0.2	-0.1	-0.2
Number of treatments/medications taken	0.1	0.2	0.9	0.4	-0.2	0.1	0.2	-0.6	-0.3	0.6	0.7	-0.0	-0.9	-0.0	-0.5	-0.2
Trunk fat percentage	0.1	0.4	1.1	-0.3	-0.7	-0.8	0.9	-0.3	0.6	0.5	0.8	-0.4	-0.0	-0.8	-1.1	-0.6
Trunk fat mass	0.1	0.3	1.1	-0.4	-0.0	-0.7	0.7	0.3	1.0	0.3	0.5	0.1	0.6	0.5	-0.3	0.3
Waist circumference	0.1	0.5	2.2	0.3	0.2	-0.5	1.5	0.3	1.1	0.3	0.4	0.3	1.0	0.6	0.0	0.8
Allergy	0.1	0.2	0.6	-0.6	-0.4	-0.8	0.6	-0.3	0.1	-0.2	-0.2	-0.4	-0.6	0.7	-0.2	-0.3
Arm fat percentage (right)	0.1	0.2	1.5	0.1	-0.2	-1.2	0.4	0.2	0.4	-0.1	0.3	-0.0	0.8	0.1	-0.1	0.5
Noisy workplace	0.1	0.2	0.6	0.3	-0.8	-0.7	0.3	-0.3	0.1	-0.6	-0.3	-0.7	-0.1	-0.2	-0.1	0.0
Arm fat mass (right)	0.1	0.5	1.7	-0.3	0.0	-1.2	0.5	0.4	0.7	-0.4	-0.1	0.2	1.1	1.3	0.4	1.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.1	0.2	0.8	-0.6	-0.4	-0.3	-0.4	-0.3	0.1	0.3	0.4	-0.4	-0.6	0.1	-0.9	-0.3
Medication: Paracetamol	0.1	0.2	0.5	-0.3	-0.2	-0.5	-0.1	-0.5	0.5	0.7	0.6	-0.1	0.2	0.2	0.4	0.1
Hypothyroidism/myxoedema (self-reported)	0.1	0.1	0.4	-0.1	-0.6	0.1	0.4	-0.1	-0.6	0.2	0.1	-0.4	-0.1	0.3	-0.1	-0.3
Medication: Ventolin 100micrograms inhaler	0.1	0.1	0.6	-0.0	-0.1	0.1	-0.3	-0.2	-0.7	-0.0	0.0	-0.3	-0.3	0.1	-0.4	0.6
Body fat percentage	0.1	0.3	1.3	0.0	-0.6	-1.2	0.8	-0.1	0.4	0.1	0.4	-0.4	0.4	-0.4	-0.7	-0.3
Eye problems/disorders: None of the above	0.1	0.1	0.5	0.7	0.2	0.7	-0.3	0.1	-0.2	0.2	0.4	-0.0	0.3	0.1	-0.0	0.2
Heart disease (mother)	0.1	0.2	0.9	-0.2	-0.2	-0.3	0.2	0.3	-0.3	0.1	0.3	-0.1	0.1	-0.5	-1.0	-0.7
Whole body fat mass	0.1	0.4	0.9	-0.2	-0.0	-0.9	0.9	0.4	0.8	0.0	0.3	0.1	0.9	1.0	0.1	0.6
Comparative height size at age 10	0.1	0.7	1.8	-0.6	0.5	1.3	-1.0	0.2	1.2	1.3	1.3	0.5	-0.2	0.8	-0.2	0.1
Medication: Aspirin	0.1	0.1	1.1	1.0	0.2	0.0	0.4	0.3	-0.1	0.2	0.2	0.3	0.3	0.4	0.1	-0.1
Arm fat percentage (left)	0.1	0.3	1.6	-0.1	-0.4	-1.3	0.7	0.3	0.5	-0.3	0.0	-0.1	0.7	0.2	-0.2	0.5
Mineral and other dietary supplements	0.1	0.1	0.4	-0.2	-0.2	-0.6	0.3	-0.1	0.5	0.1	0.0	-0.3	-0.6	0.6	-0.3	0.0
Medication: Aspirin	0.1	0.2	1.3	1.2	0.0	-0.0	0.4	0.2	-0.4	0.1	0.1	0.1	0.1	0.5	-0.3	-0.2
Arm fat mass (left)	0.1	0.5	1.6	-0.2	0.1	-1.1	0.6	0.5	0.7	-0.4	-0.2	0.2	1.0	1.3	0.3	1.1
Guilty feelings	0.1	0.1	0.5	-0.2	0.1	-0.2	-0.5	-0.1	0.7	0.4	0.4	0.1	0.3	-0.6	0.2	-0.4
Medication: Paracetamol	0.1	0.2	0.9	0.4	0.2	-0.9	-0.4	-0.2	0.5	0.3	0.1	0.3	0.5	0.7	0.4	0.5
Blood Eosinophil Count	0.0	0.3	0.8	-0.3	-0.6	-0.5	0.9	-0.6	0.6	0.5	0.6	-0.8	0.4	-0.6	-0.4	-0.1

Hub : Genes

FMN1

Models

Trait associations