TWAS hub - FZD6

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.2460	0.0460	1.8e-15	0.117	0.135	0.140	0.145	0.126	4.9e-14	4.3e-16	9.7e-17	2.9e-17	4.1e-15
2	GTEx	Artery Aorta	0.1880	0.0620	1.3e-04	0.130	NA	0.131	NA	0.131	1.2e-07	NA	1.1e-07	NA	1.1e-07
3	GTEx	Brain Cerebellum	0.1920	0.0760	2.8e-03	0.006	NA	0.071	NA	0.020	2.0e-01	NA	3.8e-03	NA	8.2e-02
4	GTEx	Cells Transformed fibroblasts	0.2280	0.0500	1.1e-08	0.178	NA	0.189	NA	0.193	2.3e-13	NA	4.1e-14	NA	2.1e-14
5	GTEx	Colon Sigmoid	0.1910	0.0770	6.3e-03	-0.001	NA	0.025	NA	0.023	3.6e-01	NA	4.5e-02	NA	5.1e-02
6	GTEx	Colon Transverse	0.1210	0.0490	3.3e-03	0.074	NA	0.052	NA	0.080	2.2e-04	NA	1.8e-03	NA	1.2e-04
7	GTEx	Uterus	0.2990	0.1010	6.4e-04	0.194	NA	0.127	NA	0.189	8.9e-05	NA	1.6e-03	NA	1.1e-04
8	METSIM	Adipose	0.0408	0.0184	4.7e-03	0.015	0.007	0.004	0.013	0.007	2.1e-03	2.8e-02	6.1e-02	3.4e-03	2.3e-02
9	ROSMAP	Brain Pre-frontal Cortex	0.0771	0.0229	1.5e-06	0.090	0.049	0.064	0.065	0.078	1.3e-11	5.6e-07	1.2e-08	9.0e-09	3.0e-10
10	YFS	Blood	0.1367	0.0255	0.0e+00	0.056	0.100	0.101	0.105	0.099	8.7e-18	5.4e-31	2.6e-31	1.5e-32	8.8e-31
11	TCGA	Ovarian Serous Cystadenocarcinoma	0.0890	0.0450	5.0e-04	0.047	0.027	0.010	NA	0.025	4.0e-04	6.2e-03	6.2e-02	NA	7.9e-03
12	TCGA	Thyroid Carcinoma	0.0770	0.0300	7.7e-09	0.069	0.090	0.075	NA	0.095	3.1e-07	4.2e-09	9.0e-08	NA	1.7e-09

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12
Ever highly irritable/argumentative for 2 days	4.0	4.8	12.7	-1.6	-2.6	0.1	-2.8	0.3	-3.6	-3.6	-2.2	-1.7	-1.1	-2.5	-0.2
Glaucoma (self-reported)	3.8	4.4	10.3	2.6	2.5	0.2	2.3	-0.1	1.8	2.3	2.2	2.5	0.4	3.2	2.3
Chronic bronchitis/emphysema (father)	2.7	3.1	7.4	0.4	2.3	0.7	2.3	1.9	2.5	2.7	1.7	-0.5	-1.5	1.8	0.1
Eye problems/disorders: Glaucoma	2.7	3.2	10.1	1.5	2.5	0.3	2.1	-0.3	1.5	2.1	1.4	1.4	-0.3	3.2	2.2
Alzheimer’s Disease (in father)	2.5	2.7	14.6	1.3	-1.4	-1.2	0.1	-1.4	-1.4	-0.5	0.2	2.7	0.2	1.0	3.8
Diabetes (mother)	2.5	3.1	5.9	-1.9	-1.8	-2.1	-1.8	-1.3	-2.4	-2.4	-2.4	-0.7	-0.5	-1.9	0.0
Ever unenthusiastic/disinterested for a whole week	2.3	2.8	7.0	-0.9	-1.4	-1.2	-1.8	-1.6	-1.9	-1.9	-0.7	-1.9	0.1	-2.6	-2.4
Blood clot in the leg (DVT)	2.2	2.9	10.5	-2.0	-0.3	-0.9	-0.1	0.2	0.2	-0.0	-0.5	-3.2	-2.1	-2.5	-2.9
Breast cancer (self-reported)	2.2	2.6	6.5	1.0	2.5	-0.6	2.4	0.4	1.8	2.6	2.1	0.7	1.5	0.8	-0.8
Ever depressed for a whole week	2.2	2.7	5.7	0.8	-1.8	-0.7	-2.1	-1.9	-1.7	-1.9	-1.1	-0.6	1.6	-2.4	-1.9
Medication: Atenolol	2.1	2.6	8.4	-0.1	-1.5	-1.4	-1.6	-1.9	-1.5	-1.8	-1.6	1.8	0.9	0.4	2.9
Deep venous thrombosis (DVT) (self-reported)	2.1	2.8	10.6	-1.9	0.0	-1.2	0.2	0.4	0.2	0.2	-0.4	-3.3	-2.3	-2.1	-2.7
Diabetes diagnosed by doctor	1.9	3.1	7.0	1.6	2.6	-1.6	1.7	-0.3	1.8	1.9	1.6	2.2	1.2	1.9	1.7
Forced expiratory volume in 1-second (FEV1)	1.8	6.0	12.8	-2.0	-3.6	1.1	-3.3	-0.5	-2.7	-3.4	-2.1	-2.2	-3.0	-2.4	-0.4
Birth weight of first child	1.8	3.4	7.9	0.6	2.6	-0.7	2.7	0.0	1.4	2.4	2.1	0.0	-1.6	2.8	1.6
Loud music exposure frequency	1.8	1.9	5.3	1.9	2.0	1.1	1.8	0.4	1.0	1.7	2.3	0.3	-0.6	0.8	1.2
Number of children fathered	1.8	2.0	7.3	-0.9	-1.2	-1.6	-1.9	-0.8	-1.7	-1.7	-2.7	-0.6	-0.5	-1.2	-0.4
Medication: Seretide 50 evohaler	1.8	2.1	5.0	-1.8	-1.2	-0.4	-1.0	0.2	-2.2	-1.6	-2.2	-1.4	-1.7	-1.4	-0.1
Guilty feelings	1.8	2.7	6.7	0.4	-2.1	0.7	-2.6	-1.7	-2.0	-2.4	-1.3	0.3	0.7	-2.3	-0.1
Medication: Atorvastatin	1.8	2.2	5.5	0.4	2.1	0.5	2.1	0.7	2.4	2.2	1.8	0.3	0.4	1.6	-0.4
Depression (Nagel 2018)	1.7	2.6	7.3	-0.5	-1.7	1.1	-2.4	0.4	-1.5	-1.9	-1.4	-1.6	-0.9	-2.7	-1.6
Multivitamins +/- minerals	1.7	2.1	4.4	2.1	1.8	1.5	1.7	0.6	1.7	2.0	1.7	0.6	-0.3	1.4	-0.1
Noisy workplace	1.7	2.1	5.2	-0.9	1.4	-0.6	2.3	1.3	1.6	2.0	1.1	-2.3	-0.9	-0.4	-1.5
Pain type(s) experienced in last month: Hip pain	1.7	2.1	4.4	2.1	1.7	1.2	1.5	2.0	0.8	1.3	2.0	1.0	1.5	-0.9	-0.0
Number of operations (self-reported)	1.7	2.6	11.8	0.8	1.1	1.4	1.1	3.4	1.5	1.7	1.4	-0.5	1.7	-0.4	-1.8
Primary Biliary Cirrhosis	1.5	2.2	8.3	-1.3	-1.0	-0.0	-1.0	-0.3	-0.4	-0.8	-1.6	-2.2	-0.5	-2.3	-2.9
Type 2 Diabetes (T2D) (2012)	1.5	1.8	6.0	-0.1	1.4	-0.6	2.3	-0.2	1.3	1.5	0.8	0.6	-0.6	2.5	1.6
Blood Red Count	1.5	14.1	30.7	3.5	5.5	-1.1	4.9	1.2	4.3	5.1	3.8	2.6	1.9	5.1	1.7
Frequency of depressed mood in last 2 weeks	1.5	2.1	9.2	0.3	-1.7	1.3	-2.2	-0.5	-0.6	-1.3	-0.6	-0.8	0.5	-3.0	-1.8
Mouth/teeth dental problems	1.5	2.4	5.1	-1.3	-2.3	-1.8	-2.0	-0.9	-2.0	-2.2	-2.0	0.6	0.4	-0.7	0.2
Pulse wave Arterial Stiffness index	1.5	1.8	5.5	0.1	2.1	-0.2	2.3	0.9	0.9	1.8	1.6	-0.9	1.2	0.9	-0.9
Pulse wave peak to peak time	1.5	1.8	5.5	-0.4	-2.2	0.2	-2.3	-1.1	-0.9	-1.8	-1.6	0.4	-1.4	-1.1	0.6
Unable to work because of sickness or disability	1.5	2.0	5.6	2.4	1.8	1.2	1.2	0.6	1.5	1.8	1.9	0.8	0.8	0.9	0.5
Fasting Glucose	1.4	1.7	4.0	1.6	1.7	-0.8	1.0	-0.5	-0.3	0.7	1.7	1.6	-0.3	2.0	1.5
Tinnitus: Yes, but not now, but have in the past	1.4	1.5	4.4	1.7	1.4	0.0	1.2	0.4	1.3	1.3	1.1	1.1	0.2	2.1	1.2
Diverticular disease/diverticulitis (self-reported)	1.4	1.6	5.4	0.9	2.0	0.7	1.9	2.3	0.5	1.8	1.1	0.3	-0.3	0.7	0.2
Financial difficulties in last 2 years	1.4	1.9	5.2	1.9	-1.3	0.7	-1.7	-1.4	-0.9	-1.1	-0.1	2.3	1.0	-0.9	1.6
Exposure to tobacco smoke at home	1.4	1.6	3.2	-1.2	-1.7	-0.7	-1.6	-0.4	-1.3	-1.6	-1.7	0.4	0.5	-1.8	-0.5
Ever had stillbirth, spontaneous miscarriage or termination	1.4	1.5	6.2	1.2	0.7	1.0	0.4	0.5	1.9	1.1	1.3	1.5	2.5	0.3	-0.3
Smoking status: Current	1.4	2.3	9.7	-0.3	-1.5	-1.1	-1.3	-0.5	-3.1	-2.3	-1.4	-0.1	0.0	-2.1	0.8
Average weekly beer plus cider intake	1.4	2.0	4.3	-1.4	-1.5	-1.0	-1.8	0.4	-1.9	-1.9	-2.1	-1.3	0.1	-0.9	-1.0
Breast Cancer	1.3	3.0	9.7	-0.8	-2.8	-0.8	-3.1	-1.7	-1.6	-2.5	-1.7	0.2	-1.1	0.1	1.4
Prostate Cancer	1.3	1.8	5.8	-1.4	-0.6	1.9	-0.3	1.2	-1.3	-1.0	-0.3	-2.4	-1.9	-1.3	-0.5
Bipolar Disorder (2011)	1.3	1.3	2.9	1.1	1.2	1.1	1.0	1.7	1.3	1.4	1.7	0.3	0.8	0.1	-0.6
HDL Cholesterol	1.3	2.1	5.6	0.3	2.4	1.9	1.8	2.2	1.5	1.7	1.3	-0.3	0.3	0.6	-0.9
Forced vital capacity (FVC)	1.3	5.0	11.1	-1.9	-3.3	0.8	-2.8	-0.4	-2.4	-3.0	-1.8	-2.4	-2.6	-2.5	-0.7
Mouth/teeth dental problems: Bleeding gums	1.3	1.6	4.9	0.8	2.2	0.4	2.2	1.0	0.5	1.5	1.8	-0.2	-0.5	1.4	0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.3	1.6	7.2	-0.7	1.3	1.7	0.6	2.7	0.9	1.0	0.2	-0.9	0.6	-0.6	-1.6
Alcohol drinker status: Never	1.3	1.5	5.8	-1.3	-0.5	-0.4	-0.7	0.2	0.3	-0.4	-0.7	-1.8	1.0	-2.2	-2.4
Schizophrenia (2014)	1.2	2.6	9.8	2.8	0.4	1.6	-0.7	0.9	1.0	0.3	0.6	3.1	2.5	0.6	1.0
Smoking Status	1.2	2.8	6.3	-1.0	-1.5	-1.8	-1.7	-1.4	-2.2	-2.0	-2.5	-0.8	-1.5	-1.7	0.8
Medication for hormone replacement therapy	1.2	1.4	5.8	1.0	-1.5	0.5	-1.3	-0.3	0.8	-0.2	-0.5	1.4	2.4	-0.7	-1.5
Had other major operations	1.2	1.4	5.5	2.3	1.1	0.1	1.2	0.9	0.8	1.6	1.5	0.2	0.9	-0.3	-1.3
Prospective memory result	1.2	1.5	4.9	-2.2	-0.9	-1.6	-0.7	-0.0	-1.1	-0.7	-1.3	-1.9	-1.4	-0.7	-0.3
Forced expiratory volume in 1-second (FEV1), Best measure	1.2	3.7	8.3	-1.6	-2.9	0.2	-2.7	-1.3	-2.1	-2.7	-1.5	-1.7	-1.9	-1.8	-1.0
Peak expiratory flow (PEF)	1.2	2.9	6.5	-1.4	-2.1	0.8	-2.3	-0.2	-2.1	-2.5	-1.1	-0.7	-2.5	-1.8	0.8
Loneliness, isolation	1.2	1.7	4.5	1.4	0.7	2.1	0.4	0.8	1.2	0.9	1.4	0.7	2.1	-0.7	-1.6
Ever had bowel cancer screening	1.2	1.4	5.3	0.4	1.5	2.3	1.1	0.6	1.7	1.5	0.6	-0.7	0.0	0.5	-1.1
Friendships satisfaction	1.2	1.5	5.1	0.5	1.6	1.4	0.8	-0.7	2.3	1.5	1.9	-0.4	-0.2	0.4	-1.0
Mouth/teeth dental problems: Mouth ulcers	1.2	1.9	4.8	0.3	2.2	1.6	1.9	0.6	1.0	1.9	2.0	-1.3	-0.5	0.2	-0.6
Medication: Lisinopril	1.2	1.5	8.0	0.5	-0.3	-2.8	0.0	-0.8	-0.5	-0.3	-0.6	1.6	0.9	0.4	2.2
Pain experienced in last month	1.2	2.0	4.9	-2.0	-1.4	0.1	-1.8	0.2	-0.8	-1.4	-2.2	-1.9	-0.8	-1.2	-1.3
Crohns Disease (2017)	1.1	2.4	6.0	-0.2	-2.5	-0.6	-2.4	0.0	-1.3	-2.1	-1.7	0.6	1.3	-2.2	-0.4
Eye problems/disorders: Diabetes related eye disease	1.1	1.2	2.8	-0.3	-1.2	-1.5	-1.1	-0.3	-0.8	-1.3	-1.3	1.4	0.4	0.3	1.7
Angina	1.1	1.5	2.8	1.1	1.6	0.2	1.4	0.5	1.4	1.6	1.5	1.1	0.4	1.7	1.1
Supplements: Zinc	1.1	1.2	3.3	0.2	-1.1	1.0	-1.7	-1.2	-0.4	-1.0	-0.9	-1.0	-0.4	-1.8	-1.1
Medication: Co-codamol	1.1	1.3	6.7	-0.2	1.5	0.5	1.7	2.6	0.0	1.2	0.6	-0.7	-0.4	-0.1	-0.6
Frequency of tenseness / restlessness in last 2 weeks	1.1	1.7	5.6	-0.6	-0.4	2.0	-1.0	1.2	-1.3	-1.1	-0.4	-1.4	0.0	-2.4	-1.4
Diabetes (self-reported)	1.1	1.6	4.3	0.7	2.1	-1.3	1.1	-0.1	1.2	1.3	0.8	1.8	1.3	1.4	1.0
Qualifications: NVQ or HND or HNC or equivalent	1.1	1.3	4.0	0.8	2.0	-1.3	1.3	0.5	0.0	1.0	0.3	0.0	-1.0	1.9	1.2
Illness, injury, bereavement, stress in last 2 years	1.1	1.3	4.3	-2.1	1.0	-0.9	1.1	1.4	0.5	0.5	0.4	-1.9	-1.4	-0.1	-0.6
Knee pain experienced in last month	1.1	1.7	5.3	-1.1	-2.3	-0.9	-1.7	-0.6	-1.3	-1.8	-1.3	0.3	-0.3	-1.4	1.0
Qualifications: nursing, teaching	1.1	1.7	6.1	-2.4	1.2	0.1	0.8	0.5	0.3	0.4	0.3	-2.3	-2.5	0.6	-0.7
Tinnitus: Yes, now most or all of the time	1.1	1.3	3.5	0.8	1.2	0.1	1.7	1.1	0.4	1.1	1.9	-1.6	-0.9	-1.2	0.0
Age at First Birth	1.0	1.5	7.4	-2.0	0.2	0.7	0.5	0.4	-0.7	-0.2	0.2	-2.7	-1.9	0.1	-1.2
Lung FEV1/FVC ratio	1.0	5.1	12.9	-2.2	-2.9	-0.9	-3.4	-1.5	-2.7	-3.6	-3.5	-0.1	-0.7	-1.1	-0.1
Current tobacco smoking	1.0	1.6	7.8	-0.1	-1.0	-0.9	-0.7	0.0	-2.8	-1.9	-1.0	-0.1	0.0	-1.9	0.8
Average weekly fortified wine intake	1.0	1.2	4.5	1.2	0.8	0.5	0.8	-0.7	2.1	1.5	1.7	-0.2	0.4	0.8	-0.8
Frequency of unenthusiasm / disinterest in last 2 weeks	1.0	1.4	6.5	0.4	-0.8	1.3	-1.6	1.0	-1.0	-1.1	-0.4	-0.7	-0.1	-2.6	-1.1
Alcohol intake versus 10 years previously	1.0	1.4	6.9	1.4	-0.8	-0.4	-0.6	-0.7	0.3	-0.0	0.2	2.6	2.5	-0.1	0.3
Hair/balding pattern: Pattern 4	1.0	2.4	10.7	1.9	-0.0	1.2	0.6	0.7	0.3	0.4	0.6	2.6	0.7	2.3	3.3
Medication: Blood pressure	1.0	1.7	9.8	-0.7	0.6	-3.1	1.1	-1.4	-0.6	0.3	-0.4	0.5	-0.9	1.3	1.9
Heart disease (mother)	1.0	1.3	3.6	1.4	0.5	1.1	0.2	-0.6	0.5	0.6	0.3	1.9	1.8	1.5	1.1
Illnesses of father: Heart disease	1.0	1.4	3.1	0.6	0.8	1.5	1.2	1.3	1.8	1.5	1.0	0.7	1.3	1.0	-0.5
Smoking status: Previous	1.0	1.4	8.1	-1.4	0.9	-0.3	0.7	-0.1	0.7	0.9	-0.5	-2.0	-2.9	0.4	-0.2
Handedness (chirality/laterality): Left-handed	1.0	1.2	3.3	-0.4	0.8	-1.5	0.6	-1.6	-1.1	-0.1	-1.2	-1.5	-0.5	-0.6	-1.8
Illnesses of father: None of the above (group 1)	1.0	1.3	3.3	-0.4	-1.2	-0.5	-1.4	-1.5	-1.8	-1.7	-0.7	-0.8	-0.6	-1.0	0.4
Verbal and Numeric Reasoning (VNR)	0.9	2.2	4.9	-1.3	2.2	0.5	1.8	1.5	1.7	1.7	1.5	-0.9	-1.4	1.7	0.3
Blood White Count	0.9	6.5	22.1	0.6	4.1	-4.7	4.5	-1.3	1.4	3.3	1.4	0.3	0.7	1.3	-0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.9	2.1	4.5	1.6	1.4	0.1	1.7	-1.7	1.0	1.3	2.0	1.2	-0.2	2.1	1.3
Serious illness, injury or assault to yourself	0.9	1.1	3.6	-0.5	0.3	0.9	0.8	-0.1	1.9	1.4	0.4	-1.0	-1.5	0.3	-1.5
Stomach or abdominal pain in last month	0.9	1.2	3.9	-1.5	-1.3	0.7	-0.7	1.6	-0.8	-0.8	-0.3	-0.7	-0.2	-2.0	-1.0
Medication: Levothyroxine sodium	0.9	1.6	5.2	1.7	0.4	0.0	0.8	-1.7	0.4	0.6	0.6	1.4	-0.4	1.9	2.3
Depression (self-reported)	0.9	1.1	4.0	2.0	-0.0	2.0	-0.9	0.5	1.4	0.4	0.4	1.0	0.9	-0.1	-0.4
Qualifications: O levels/GCSEs or equivalent	0.9	1.4	3.5	1.0	1.4	-0.2	1.2	0.2	1.7	1.4	1.3	0.4	1.1	1.9	0.7
Medication for cholesterol, blood pressure or diabetes	0.9	1.5	5.3	-0.4	-1.1	2.3	-1.3	1.2	-0.3	-0.8	-0.1	-1.5	-0.4	-1.5	-1.5
Wheeze or whistling in the chest in last year	0.9	1.6	4.9	2.2	1.4	1.0	1.2	0.5	0.9	1.4	1.2	1.2	0.0	1.4	1.5
Shortness of breath walking on level ground	0.9	1.1	2.6	-0.6	-1.4	-1.1	-1.6	-0.6	-0.7	-1.1	-1.5	0.2	0.7	-1.4	-0.4
Osteoporosis (self-reported)	0.9	1.2	2.5	0.6	1.2	1.1	1.2	1.6	1.3	1.0	1.2	0.8	0.9	0.9	0.6
Ever taken oral contraceptive pill	0.9	1.0	2.8	-1.2	-1.0	-0.5	-0.9	-0.1	-0.3	-0.5	-1.3	-1.3	-0.7	-1.7	-1.2
High cholesterol (Self-reported)	0.9	1.5	3.4	0.6	1.2	0.8	1.5	1.3	1.8	1.8	1.1	0.7	1.3	1.2	-0.3
Medication: Paracetamol	0.9	1.3	2.4	1.1	-1.1	1.1	-1.4	1.2	-1.1	-1.1	-1.3	1.6	1.0	-0.1	1.2
Cholesterol lowering medication	0.9	1.3	3.0	0.2	1.6	0.3	1.6	0.5	1.7	1.7	1.3	0.7	0.7	1.3	0.8
Intelligence (Savage-Jansen 2018)	0.8	2.3	8.2	-2.5	1.3	-0.8	1.2	0.5	0.7	0.9	1.0	-2.9	-2.1	-0.4	-1.6
Alzheimer’s Disease (in mother)	0.8	0.9	5.0	1.0	0.4	2.2	0.4	1.0	1.1	0.6	0.7	0.7	0.9	-0.1	0.3
Alzheimer’s Disease (including proxy)	0.8	1.2	4.4	1.5	-0.1	1.2	0.4	0.4	0.2	0.4	1.1	2.1	1.0	0.4	2.0
Reaction Time	0.8	1.5	4.2	-1.2	-2.0	0.2	-1.1	0.2	-0.8	-1.3	-2.0	-1.4	-0.7	-1.4	-0.9
HbA1C	0.8	0.9	2.9	0.6	0.8	0.4	1.1	0.3	-0.3	0.5	0.2	1.4	0.9	1.7	1.7
Respiratory disease	0.8	1.9	5.5	0.8	1.4	2.4	0.9	2.2	1.7	1.4	0.9	-1.1	-0.7	-0.2	-0.9
Type 2 Diabetes (T2D) (2018)	0.8	1.6	4.1	0.5	2.0	-2.0	0.9	-1.1	0.4	0.7	0.5	1.8	1.1	1.2	1.3
Number of treatments/medications taken	0.8	1.5	4.7	1.3	0.8	0.2	0.9	1.4	0.8	1.1	-0.2	2.2	1.9	0.8	1.1
Medication: Metformin	0.8	1.2	3.1	0.5	1.8	-1.5	1.0	-0.3	1.6	1.2	0.7	0.8	1.2	1.0	0.0
Taking other prescription medications	0.8	1.3	4.3	2.1	0.9	0.5	0.9	-0.2	0.6	1.0	0.3	2.0	1.8	0.2	0.5
Bilateral oophorectomy (both ovaries removed)	0.8	1.0	4.1	-0.4	-0.8	0.7	-0.8	-0.1	-0.5	-0.7	-1.1	-0.7	0.2	-1.8	-2.0
Number of incorrect matches in round	0.8	1.3	2.4	0.9	0.6	-1.5	1.5	-1.3	1.5	1.4	1.4	-0.2	-0.8	0.9	0.7
Past tobacco smoking	0.8	1.5	6.3	1.5	0.4	0.5	0.6	1.0	0.7	0.6	1.4	2.0	2.5	0.7	0.0
Hearing difficulty/problems with background noise	0.8	1.4	3.4	1.6	1.5	0.9	1.5	0.2	1.6	1.9	1.4	0.1	-0.0	-0.2	0.0
Falls in the last year	0.8	1.1	4.6	0.7	0.1	1.2	-0.3	2.1	-1.3	-0.9	-0.5	0.7	1.5	-0.3	0.8
Pulse wave reflection index	0.8	1.0	3.1	-0.7	0.2	-1.7	0.1	-1.0	-0.5	-0.2	-0.6	-1.7	-0.5	-0.6	-1.8
Chronic bronchitis/emphysema (mother)	0.8	1.0	3.3	1.0	0.9	-0.1	0.8	0.4	1.8	1.8	0.7	0.4	0.3	1.1	-0.7
Mouth/teeth dental problems: Loose teeth	0.8	0.9	2.6	-0.0	1.4	-0.8	0.5	0.5	1.1	1.1	-0.3	-1.5	-0.4	0.6	-1.6
Mineral and other dietary supplements	0.8	1.1	3.1	-1.4	-0.6	-1.8	-0.9	-1.5	-1.2	-1.0	-0.9	-0.3	0.3	-0.9	0.2
Medication: Gliclazide	0.8	0.9	2.7	1.1	1.5	-0.5	1.7	-0.0	0.3	1.1	0.8	0.3	-0.3	1.0	1.0
Commuting to job workplace: Public transport	0.8	0.9	4.0	1.9	0.2	2.0	0.4	-0.1	0.4	0.4	1.2	0.2	-0.7	0.9	0.8
Medication: Blood pressure	0.8	1.5	10.6	-1.5	-0.1	-3.3	-0.3	-1.2	0.3	-0.1	-1.3	0.1	0.1	1.0	1.2
Supplements: Fish oil (including cod liver oil)	0.8	1.0	2.2	1.0	0.9	1.4	1.1	1.0	1.5	1.3	0.6	0.3	-0.2	1.4	-0.2
Medication: Omeprazole (e.g. Zanprol)	0.8	1.0	2.4	0.1	1.4	0.8	1.2	-0.6	1.2	1.6	1.1	-0.9	-0.7	0.5	-0.5
Heart attack/myocardial infarction (self-reported)	0.8	1.0	2.3	1.1	0.6	0.4	0.9	1.5	1.4	1.3	1.0	0.4	1.5	0.6	0.1
Pack years of smoking	0.8	1.2	2.1	1.3	1.5	0.8	1.1	1.3	0.9	1.1	1.4	1.2	1.3	-0.1	0.8
Bipolar Disorder or Schizophrenia	0.7	1.8	4.3	2.0	0.3	1.8	-0.4	2.1	1.5	0.8	1.1	1.9	1.2	0.8	0.4
Schizophrenia (2018)	0.7	1.5	4.9	2.2	0.5	0.6	-0.2	1.1	1.4	0.8	0.8	2.2	1.6	0.5	0.3
LDL Cholesterol	0.7	1.1	2.3	-0.6	1.2	1.2	1.4	1.5	1.3	1.5	0.8	-0.3	-0.2	0.2	-1.1
Pack years adult smoking proportion	0.7	1.1	1.9	1.0	1.4	0.8	0.9	1.2	0.8	0.9	1.3	1.1	1.3	-0.3	0.7
Townsend deprivation index at recruitment	0.7	1.0	2.4	1.6	1.0	1.4	0.5	0.4	0.0	0.3	1.1	1.4	1.0	0.4	1.2
Relative age voice broke	0.7	1.1	4.2	2.0	1.1	1.0	0.9	-0.4	0.3	0.8	1.3	1.4	1.4	0.0	0.2
Time employed in main current job	0.7	0.8	3.0	0.9	-0.8	-0.4	-0.8	-1.7	0.2	-0.2	-0.6	0.7	1.4	0.1	-1.4
Hypothyroidism/myxoedema (self-reported)	0.7	1.4	7.2	1.3	-0.8	-1.1	-0.4	-2.7	-0.3	-0.6	-0.7	1.0	-0.0	1.0	1.5
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.8	3.4	-0.4	-0.2	-0.4	0.4	-0.3	-0.4	-0.2	0.1	-1.8	0.3	-1.4	-1.8
Eye problems/disorders: None of the above	0.7	0.8	3.4	-0.4	-1.0	-1.5	-0.5	0.3	-1.8	-0.9	-0.7	0.2	0.1	-1.0	0.7
Commuting to job workplace: Car/motor vehicle	0.7	0.8	2.7	0.8	1.1	1.0	0.1	0.6	1.0	0.8	0.5	1.1	1.6	0.5	-0.2
Supplements: Vitamin C	0.7	0.9	3.5	1.1	-0.7	1.9	-0.8	0.9	-0.3	-0.5	0.1	1.1	-0.3	0.4	1.4
Illnesses of siblings: Diabetes	0.7	0.9	3.0	-0.2	-0.7	-1.0	-1.2	-1.0	0.4	-0.8	0.4	1.6	1.7	-0.4	0.4
Eye problems/disorders: Cataract	0.7	0.8	3.5	0.3	0.7	1.9	0.2	0.9	1.6	0.7	0.9	-0.3	-0.3	0.4	-0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.7	0.8	2.2	-1.5	-0.4	1.0	-0.2	0.8	-0.6	-0.7	-0.7	-1.5	-0.3	-1.3	-0.8
Hearing aid user	0.7	0.7	2.7	-0.2	-0.9	-0.7	-1.2	-0.9	-0.5	-0.6	-1.6	-0.6	-0.4	-1.2	-0.5
Financial situation satisfaction	0.7	0.8	3.4	1.8	0.8	0.8	-0.0	0.1	-0.1	0.1	1.0	1.4	0.3	-0.2	1.4
Medication: Bendroflumethiazide	0.7	1.1	4.8	-1.5	0.6	-2.2	1.2	-0.1	0.4	0.7	-0.1	0.3	-0.1	1.1	1.3
Ever had prostate specific antigen (PSA) test	0.7	0.8	2.7	0.6	1.0	0.9	0.7	-0.8	0.8	0.8	1.6	0.7	1.1	0.6	-0.0
Diastolic blood pressure, automated reading	0.7	2.1	6.5	-1.3	-1.0	-2.0	-1.0	-0.7	-2.5	-1.7	-1.7	-0.3	-1.6	-0.3	1.3
Heart disease (siblings)	0.7	0.8	3.3	-0.8	0.6	-0.4	0.9	0.3	0.9	0.8	1.2	-0.7	-1.8	0.3	1.0
Bipolar Disorder (2018)	0.6	0.9	4.5	0.5	0.1	2.1	-0.4	1.9	0.6	0.2	0.9	0.3	-0.1	0.7	0.4
Schizophrenia vs Biploar Disorder	0.6	0.8	3.0	1.7	0.7	0.0	0.6	-0.9	0.6	0.6	0.8	1.5	0.7	0.0	0.5
Body Mass Index (BMI) (2010)	0.6	0.8	2.8	-1.1	-0.9	-0.6	-0.7	0.8	0.4	-0.4	-1.2	-0.5	1.7	-0.5	-1.2
Neuroticism (2016)	0.6	0.9	2.9	-0.7	-0.4	-0.6	-0.6	-0.1	-1.7	-1.1	-1.0	-1.1	0.2	-1.7	-0.2
Hypothyroidism (self reported)	0.6	1.3	4.2	1.9	-0.3	-1.1	0.1	-2.0	-0.7	-0.2	-0.3	1.4	0.4	1.0	1.7
Ever used hormone-replacement therapy (HRT)	0.6	0.8	2.5	-0.6	0.4	1.6	0.5	1.1	0.3	0.6	0.4	-1.3	-0.3	-0.8	-1.5
Hand grip strength (right)	0.6	1.5	6.0	1.5	1.6	0.9	1.0	-0.1	1.4	1.1	2.4	0.1	-1.2	0.9	0.7
Heart attack	0.6	0.8	1.9	1.2	0.5	0.2	0.7	1.1	1.3	1.1	0.9	0.4	1.4	0.7	0.2
Father’s age at death	0.6	0.8	1.8	-0.1	0.5	1.2	1.4	0.6	1.2	1.1	0.7	-0.4	-0.8	1.2	-0.1
Frequency of tiredness / lethargy in last 2 weeks	0.6	1.0	5.0	1.3	-0.2	2.2	-0.7	-0.1	-0.9	-0.5	0.1	-0.3	0.4	-1.7	-0.6
Hair/balding pattern: Pattern 3	0.6	1.0	3.7	-0.6	1.4	-0.4	1.9	-0.1	0.1	1.2	0.8	-0.1	-1.2	0.8	1.0
Happiness	0.6	0.7	3.9	-0.0	-0.4	0.6	-1.3	-1.1	-0.5	-1.0	0.1	-0.5	-0.2	-2.0	-0.4
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.7	2.0	-0.1	-0.7	-0.2	-1.0	-0.7	-1.4	-1.1	-0.4	0.8	1.3	-0.4	0.4
Medication: Lansoprazole	0.6	0.7	3.3	-0.4	0.8	0.2	1.4	1.8	0.0	0.9	0.5	0.0	-0.3	-0.0	0.9
Tense / ‘highly strung’	0.6	1.0	4.6	-1.5	-0.2	0.4	-0.4	-0.0	0.1	-0.1	-0.3	-1.1	-0.0	-2.1	-1.7
Medication: Paracetamol	0.6	1.0	3.0	1.4	-0.8	1.2	-1.1	0.6	-0.5	-0.6	-0.8	1.7	1.2	-0.0	1.1
Headache pain in last month	0.6	1.1	5.2	1.5	0.2	0.2	0.7	0.2	0.1	0.7	0.6	2.3	1.4	0.8	1.2
Medication: Amlodipine	0.6	0.9	2.1	0.6	-1.5	-0.7	-1.3	-0.9	-1.1	-1.1	-0.4	-0.0	1.1	-1.2	-0.1
Medication: Ventolin 100micrograms inhaler	0.6	0.7	1.9	-1.4	-0.9	0.3	-0.8	1.1	-0.4	-0.7	-1.2	-1.1	-0.1	-0.8	-0.6
High blood pressure (siblings)	0.6	0.8	3.6	-0.2	0.1	-1.1	0.2	0.1	-1.2	-0.4	1.0	1.4	0.9	-0.0	1.9
Forced vital capacity (FVC), Best measure	0.6	2.2	5.2	-1.1	-2.3	0.1	-2.0	-1.2	-1.5	-1.9	-0.7	-1.5	-1.5	-1.6	-0.9
Number of full brothers	0.6	0.7	2.8	-0.2	-1.5	-0.3	-1.7	-0.1	0.1	-0.8	-0.6	0.7	-0.7	-0.1	1.4
Neck or shoulder pain in last month	0.6	0.9	2.5	0.9	1.5	-1.6	1.3	-0.5	0.5	1.2	1.1	0.4	-0.1	0.3	0.4
Angina (self-reported)	0.6	0.8	1.9	0.9	1.1	0.1	1.0	0.3	1.0	1.1	1.0	0.9	0.4	1.4	1.0
Alcohol intake frequency.	0.6	1.3	4.1	0.8	0.6	0.0	0.5	0.6	2.0	1.3	1.5	1.2	2.0	-0.2	-0.9
Number of full sisters	0.6	0.7	2.7	1.6	0.8	-0.3	0.6	0.3	-0.2	0.7	0.2	1.1	1.6	0.2	0.1
Had major operations	0.6	0.8	2.8	0.6	1.2	0.8	0.8	1.7	0.5	0.8	0.8	-0.7	0.5	-0.5	-0.8
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.2	3.6	0.2	-1.3	-0.2	-1.5	-0.3	-1.2	-1.2	-0.9	-1.4	-1.0	-1.9	-0.9
Mood swings	0.6	1.1	2.5	-0.3	-1.4	-0.9	-1.2	-0.7	-1.3	-1.3	-1.6	0.8	0.2	-1.4	0.3
Long-standing illness, disability or infirmity	0.6	0.8	4.0	2.0	0.4	-1.0	0.3	-0.9	0.2	0.5	0.5	0.9	0.8	-1.3	0.5
Ever smoked	0.6	1.0	3.2	-1.2	-0.6	0.2	-0.6	-0.1	-1.3	-1.0	-1.1	-1.6	-1.8	-0.7	0.4
Risk taking	0.6	0.9	2.1	-0.3	-1.4	-1.1	-0.9	-1.4	0.1	-0.7	-0.6	1.1	0.9	0.5	0.9
Fractured/broken bones in last 5 years	0.6	0.7	2.6	-1.6	0.1	-0.3	0.4	0.9	0.4	0.4	0.1	-1.4	-0.1	-1.1	-1.3
Age started oral contraceptive pill	0.6	0.8	1.9	-0.2	0.5	0.7	1.4	0.7	1.1	1.3	0.6	-1.3	-0.3	-0.1	-1.1
Irritable Bowel Disease (IBD)	0.5	1.2	3.7	1.1	-1.4	-0.7	-1.5	0.7	-0.5	-1.0	-0.6	1.1	1.9	-1.2	-0.3
Ovarian Cancer	0.5	0.6	2.9	-1.2	0.1	0.7	0.1	0.7	-0.5	-0.3	-0.1	-1.0	-1.7	-0.6	0.6
Triglycerides	0.5	0.8	1.7	0.7	0.6	0.2	1.3	0.9	1.1	1.3	0.9	0.7	0.4	1.0	0.7
Neuroticism	0.5	1.2	4.0	-0.9	-0.8	0.6	-1.4	-0.6	-0.9	-1.3	-1.5	-0.5	-0.4	-2.0	-0.8
Average weekly spirits intake	0.5	0.6	1.6	-0.4	-1.3	-1.2	-1.0	-0.7	0.1	-0.7	-0.4	-0.6	0.3	-1.0	-0.6
Other serious medical condition/disability diagnosed by doctor	0.5	0.6	2.0	1.3	0.8	-0.0	0.6	0.1	-0.0	0.5	0.2	0.9	-1.2	0.7	1.4
Vitamin and mineral supplements	0.5	0.7	2.0	-1.1	-0.6	-1.2	-0.8	-1.0	-0.6	-1.0	-0.4	0.2	1.4	-0.5	0.2
Maternal smoking around birth	0.5	0.7	2.6	0.6	0.5	-0.4	0.8	-1.6	0.8	0.8	0.9	-0.7	-1.3	0.2	-0.4
High blood pressure	0.5	1.4	10.2	-1.2	0.5	-3.2	0.4	-1.2	-0.3	-0.2	-0.4	-0.1	-0.9	0.4	1.5
Supplements: Glucosamine	0.5	0.6	2.0	0.7	-1.2	0.5	-0.6	-1.4	0.0	-0.6	-0.1	1.0	1.1	-0.3	0.1
Hair/balding pattern: Pattern 2	0.5	0.6	2.6	-0.2	0.2	1.6	-0.5	1.2	0.7	0.1	-0.2	-0.3	0.7	-0.2	-1.2
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.1	2.8	0.6	1.0	-0.4	1.3	-1.7	0.1	0.5	1.4	0.6	-0.8	1.6	1.1
Pain all over the body in last month	0.5	0.5	3.5	0.0	0.2	-1.2	-0.2	-1.9	-0.0	0.1	-0.7	0.1	-0.1	0.3	0.5
Medication: Ramipril	0.5	0.6	1.3	0.1	0.8	-1.1	1.1	-0.9	0.9	0.9	0.7	-0.3	-0.4	0.7	-0.3
Medication: Simvastatin	0.5	0.8	1.9	-0.1	0.7	-1.2	1.0	0.1	1.0	1.2	-0.1	1.1	0.9	1.4	0.7
Qualifications: A levels/AS levels or equivalent	0.5	1.0	2.6	1.6	-0.2	0.9	-0.0	-0.7	1.4	0.4	0.9	1.5	0.3	1.1	1.2
Lung cancer (father)	0.5	0.6	3.1	0.2	-0.3	-0.6	-0.5	-1.1	-0.6	-0.6	-0.5	0.4	-0.8	0.7	1.8
Illnesses of mother	0.5	0.6	2.9	-0.4	-0.4	1.0	-0.5	1.7	-0.2	-0.7	-0.1	-0.7	-1.3	-0.6	-0.2
Length of working week for main job	0.5	0.5	2.3	1.5	0.3	-0.1	0.2	0.3	-0.7	-0.2	0.7	0.9	1.2	0.0	0.9
Breastfed as a baby	0.5	0.6	2.4	0.2	-0.5	0.6	-0.7	0.3	-0.5	-0.6	0.1	1.4	1.6	0.1	1.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.8	1.8	1.1	0.7	0.8	0.3	-0.2	0.2	0.6	1.3	-1.2	-0.2	-1.3	-1.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.7	2.1	1.2	0.4	1.1	-0.2	-0.4	-0.1	-0.1	1.4	0.8	1.2	-0.8	-0.3
Age at first live birth	0.5	0.9	2.2	-1.5	-0.2	-0.4	-0.8	-0.1	-1.2	-1.1	-1.1	-1.4	-1.2	-0.8	-0.3
Migraine (self-reported)	0.5	0.7	2.5	0.0	-0.7	-0.2	-1.2	0.3	-0.6	-0.9	-0.2	0.8	1.6	-1.1	-0.7
Mean time to correctly identify matches	0.5	0.9	3.5	-1.0	-1.6	-0.2	-0.3	-0.3	-0.1	-0.4	-1.9	-1.2	-1.1	-0.1	-0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.5	2.5	0.4	0.6	-0.2	1.0	0.8	0.2	0.3	0.5	0.3	-0.8	0.9	1.6
Chest pain or discomfort	0.5	0.7	3.7	0.3	0.6	1.9	0.5	0.9	1.2	0.9	0.5	-0.4	-0.0	-0.2	-0.3
Age at last live birth	0.5	0.7	2.4	-1.0	-0.7	-0.4	-0.7	-0.8	-1.6	-1.1	-0.9	-0.4	-0.9	-0.2	0.7
Leg pain on walking	0.5	0.7	3.8	0.9	0.8	-0.1	0.2	-0.4	0.9	0.7	0.6	0.7	2.0	-0.5	-0.6
Number of self-reported non-cancer illnesses	0.5	0.9	2.3	1.5	1.3	-0.2	0.9	0.6	0.9	1.2	0.8	0.9	1.1	0.4	0.2
Wears glasses or contact lenses	0.5	0.6	1.9	0.6	0.9	0.4	0.6	-0.9	-0.2	0.3	-0.1	0.6	-0.4	1.4	1.4
Illnesses of father: High blood pressure	0.5	0.7	2.6	0.2	0.4	-0.8	0.5	-1.6	0.1	0.0	-0.2	1.4	1.3	0.5	0.4
Irritability	0.5	0.8	3.3	-1.0	0.1	-0.2	-0.0	0.4	-1.0	-0.6	-0.2	0.3	-1.7	0.6	1.8
Commuting to job workplace: Cycle	0.5	0.6	2.0	-0.9	-0.7	0.4	0.0	1.2	-0.1	-0.2	-0.6	-1.4	0.2	-1.0	-1.0
Alcohol drinker status: Previous	0.5	0.6	3.0	0.9	-0.8	0.9	-0.1	1.7	0.4	0.2	0.3	0.8	0.4	-0.8	-0.4
Ulcerative Colitis (UC)	0.4	0.8	3.7	1.5	-0.1	-0.8	-0.1	0.7	0.5	0.4	0.5	1.5	1.9	0.3	-0.0
Major Depression (MDD)	0.4	0.4	1.6	0.1	-0.4	0.1	-0.5	-0.7	-1.3	-1.0	0.0	-0.6	-0.3	-1.0	0.1
Crohns Disease (2012)	0.4	0.7	3.1	-0.6	-1.0	-0.7	-0.9	-0.1	-0.8	-0.8	-0.5	-0.3	0.1	-1.8	-0.5
Lupus	0.4	0.6	2.0	-0.5	-0.2	0.0	0.3	0.1	0.4	0.2	-0.7	1.4	-0.3	1.3	1.4
Ulcerative Colitis	0.4	0.6	1.7	1.0	0.1	0.3	0.1	0.9	1.1	0.7	0.4	1.0	1.3	0.6	-0.4
Systolic Blood Pressure	0.4	1.8	6.9	0.3	0.5	-2.6	1.2	-0.9	-0.2	0.8	-0.4	1.9	-0.5	1.5	2.3
Lung FVC	0.4	1.9	6.6	-1.4	-1.4	1.1	-1.1	-0.5	-1.6	-2.0	-0.7	-0.6	-2.6	-0.3	1.4
Relative age of first facial hair	0.4	0.9	1.8	1.1	1.1	1.1	0.9	-0.5	0.8	1.0	1.3	0.5	1.1	0.2	-0.8
Systolic blood pressure, automated reading	0.4	1.0	2.6	-0.5	1.1	-1.6	1.5	0.2	-0.1	0.9	0.1	0.4	-1.2	1.3	1.3
Age when periods started (menarche)	0.4	1.0	2.0	1.2	0.8	1.4	0.8	1.1	0.9	1.2	0.7	0.6	1.4	-0.2	-1.1
Body mass index (BMI)	0.4	1.6	6.4	-0.0	1.0	-1.8	1.1	-0.8	-1.2	0.0	-0.3	0.5	-1.9	1.2	2.5
Waist circumference	0.4	1.3	5.5	0.5	0.3	-1.6	0.6	-1.7	-1.2	-0.3	-0.1	0.4	-1.4	0.5	2.3
Alcohol usually taken with meals	0.4	0.6	3.3	-1.3	-0.3	0.4	-0.4	-0.4	0.2	-0.2	-0.6	-1.0	-1.8	0.1	-0.7
Illnesses of siblings	0.4	0.5	1.9	0.8	-0.7	0.8	-0.7	-0.3	-0.4	-0.5	-1.4	-0.6	-0.8	-0.1	-0.8
Number of live births	0.4	0.5	1.7	-0.6	-1.1	0.2	-0.9	0.4	-0.5	-0.8	-0.8	0.5	1.3	-0.6	0.0
Pulse rate	0.4	0.6	1.5	0.3	-1.1	0.7	-0.8	1.2	-0.6	-0.8	0.6	1.1	0.5	-0.4	0.8
Asthma	0.4	0.8	3.3	1.2	0.8	1.8	0.5	1.3	0.7	0.7	0.8	-0.4	-0.2	-0.4	-0.2
Medication: Cholesterol lowering	0.4	0.6	1.9	0.1	0.5	-1.4	0.6	-0.0	1.0	0.9	-0.5	0.8	0.7	1.2	0.4
Comparative body size at age 10	0.4	1.0	2.3	-0.5	0.9	-1.4	0.9	-1.5	0.5	0.3	0.6	0.0	-1.1	1.3	1.4
Worry too long after embarrassment	0.4	0.7	1.7	-1.2	-0.9	0.8	-1.2	0.2	-0.6	-1.2	-1.3	-0.2	0.5	-0.8	0.1
Health satisfaction	0.4	0.5	2.5	-0.1	-0.2	-0.6	-0.7	-0.8	0.0	-0.4	0.1	-0.8	-0.4	-1.6	-0.8
Medication: Ibuprofen	0.4	0.5	1.4	-0.3	-0.6	-0.6	-0.5	0.7	-1.2	-0.7	-0.1	0.1	-0.8	-1.2	0.3
Medication: Allopurinol	0.4	0.5	2.0	0.8	-0.0	-0.7	0.0	-0.4	-0.3	0.1	0.2	0.8	-0.7	1.1	1.4
Medication: Omeprazole	0.4	0.5	1.4	-0.0	1.2	1.1	0.7	0.2	0.8	1.1	0.5	-0.6	-0.7	0.2	-0.5
Hypertension (Self-reported)	0.4	1.2	9.6	-1.2	0.5	-3.1	0.4	-1.0	0.0	-0.0	-0.7	-0.0	-0.5	0.4	1.1
Medication for cholesterol	0.4	0.5	1.9	0.6	-0.2	1.0	-0.1	-0.0	-1.0	-0.7	0.4	-1.0	-1.4	-0.8	-0.2
Back pain experienced in last month	0.4	0.6	1.9	1.1	-1.4	0.5	-0.8	0.6	-0.8	-0.8	0.2	0.1	0.5	-1.2	-0.3
Medication: Aspirin	0.4	0.6	2.4	0.5	0.2	0.3	-0.0	-0.2	0.7	0.4	-0.0	1.5	1.6	0.6	0.8
Average weekly champagne plus white wine intake	0.4	0.5	1.9	1.4	-0.7	1.0	-0.2	-0.0	0.6	0.1	0.6	1.1	-0.1	0.6	0.4
Leg fat percentage (left)	0.4	1.3	4.0	-0.9	0.3	-1.7	0.6	-1.0	-1.7	-0.5	-1.0	-0.9	-2.0	0.4	1.3
Vascular/heart problems diagnosed by doctor	0.4	1.0	6.2	0.2	-0.8	2.5	-0.6	0.8	-0.4	-0.3	-0.1	-0.3	0.5	-0.9	-1.7
Worry (Nagel 2018)	0.3	0.6	2.4	-1.2	-0.1	0.5	-0.7	-0.0	-0.3	-0.3	-1.1	-0.7	-0.5	-1.6	-0.8
Coronary Artery Disease (CAD)	0.3	0.3	0.6	-0.2	0.7	-0.7	0.6	0.6	0.6	0.5	-0.1	-0.8	-0.7	-0.5	-0.1
BMI	0.3	1.8	6.1	-0.1	1.1	-2.4	1.1	-1.0	-1.7	-0.2	-0.4	1.2	-1.0	0.9	2.5
Waist Hip Ratio (WHR)	0.3	1.2	7.8	-0.3	-0.3	-2.8	0.3	-1.9	0.5	0.2	0.0	0.4	1.1	-0.9	-0.5
Allergy or Eczema	0.3	0.7	1.8	0.6	1.3	0.2	1.2	-0.0	-0.4	0.6	0.8	-0.1	-1.3	0.7	1.0
Cardiovascular Disease	0.3	1.1	6.2	-0.0	1.0	-2.5	1.0	-0.7	0.2	0.6	0.0	1.4	0.2	0.8	1.2
Chronotype (morning person)	0.3	0.7	3.5	-0.3	-0.1	-1.2	-0.1	0.2	-0.2	-0.2	0.4	1.6	-0.3	0.2	1.9
Tanning	0.3	3.4	9.3	2.8	1.2	0.7	1.1	-0.3	1.3	1.5	1.8	2.7	0.2	2.5	3.0
Hand grip strength (left)	0.3	0.9	2.4	0.4	0.4	0.7	-0.1	-1.5	1.5	0.5	1.4	-0.4	-1.6	0.7	0.1
Ever had hysterectomy (womb removed)	0.3	0.3	1.0	-0.1	-0.4	0.1	-0.5	0.0	-0.5	-0.8	-0.5	0.1	1.0	-0.9	-0.8
Severe depression (siblings)	0.3	0.3	0.8	-0.4	-0.1	-0.8	-0.1	0.6	-0.9	-0.4	-0.4	-0.6	-0.4	-0.5	-0.5
Impedance of leg (right)	0.3	1.6	3.0	-0.5	-1.6	0.8	-1.4	0.5	-1.5	-1.4	-1.2	-1.1	1.2	-1.7	-1.7
Trunk fat percentage	0.3	1.1	3.9	-0.2	-0.0	-0.7	0.6	-0.6	-1.8	-0.6	-0.9	-0.3	-2.0	0.4	2.0
High blood pressure (mother)	0.3	0.5	2.7	0.1	0.8	-0.3	0.9	-1.6	-0.0	0.5	0.7	-0.4	0.4	-0.3	-0.5
Impedance of leg (left)	0.3	1.6	3.8	-0.6	-2.0	0.3	-1.6	-0.2	-1.3	-1.4	-1.4	-1.2	0.6	-1.4	-1.6
Trunk fat mass	0.3	1.1	4.9	-0.2	-0.1	-0.9	0.4	-0.8	-1.7	-0.5	-0.8	-0.5	-2.2	0.3	1.7
Had menopause	0.3	0.4	1.7	1.3	0.5	1.0	0.2	0.2	0.3	0.5	0.0	-0.3	1.0	0.3	-0.5
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	1.1	-0.3	-0.7	-1.0	-0.4	-0.9	-0.9	-0.6	-1.0	0.1	0.3	-0.4	0.1
Arm fat percentage (right)	0.3	1.2	6.8	0.2	1.0	-0.5	1.2	-0.5	-0.9	0.1	0.4	0.7	-1.2	1.4	2.6
Worrier / anxious feelings	0.3	0.5	1.5	0.6	-0.3	-0.6	-0.3	-0.8	-1.0	-0.4	-0.8	1.2	0.5	-0.7	0.8
Impedance of arm (left)	0.3	1.6	6.2	-0.5	-1.6	2.5	-1.5	1.0	-0.2	-1.1	-0.6	-0.9	0.6	-1.3	-1.3
Arm fat mass (right)	0.3	1.1	5.0	0.1	0.7	-1.0	0.9	-0.7	-1.2	-0.1	0.0	0.3	-1.7	0.9	2.2
Gout (self-reported)	0.3	0.4	1.3	0.5	0.2	-0.7	-0.0	-1.2	-0.6	-0.2	0.4	0.6	-0.5	0.6	0.9
Body fat percentage	0.3	1.1	3.9	-0.2	0.2	-1.0	0.7	-0.5	-1.8	-0.5	-0.7	-0.2	-1.8	0.6	2.0
Leg fat percentage (right)	0.3	1.1	3.8	-0.9	0.5	-1.4	0.8	-0.4	-1.9	-0.5	-0.9	-0.8	-1.7	0.2	1.3
Exposure to tobacco smoke outside home	0.3	0.4	1.7	0.8	0.4	-0.1	1.3	1.2	-0.3	0.5	0.3	0.3	-0.5	0.2	0.4
Emphysema/chronic bronchitis	0.3	0.3	1.0	0.4	-0.0	-0.4	0.0	0.8	1.0	0.3	0.8	0.4	-0.1	0.1	0.8
Medication for pain relief, constipation, heartburn	0.3	0.5	1.7	-0.3	0.0	-1.0	0.1	-1.3	0.2	0.0	0.0	-1.2	-1.0	0.5	-0.8
Whole body fat mass	0.3	1.2	4.9	-0.4	0.1	-1.2	0.6	-0.4	-1.6	-0.4	-0.7	-0.5	-2.2	0.5	1.9
Leg fat mass (right)	0.3	1.1	3.9	-0.3	0.6	-1.4	1.0	-0.4	-1.4	-0.1	-0.4	-0.5	-2.0	0.4	1.6
Pulse rate, automated reading	0.3	1.1	3.7	0.9	1.4	-0.6	1.4	0.5	0.1	0.9	1.9	0.9	-0.7	0.6	1.1
Suffer from ‘nerves’	0.3	0.5	2.8	0.3	0.2	1.7	-0.6	1.0	0.7	0.0	0.2	-0.1	0.2	-0.7	-0.8
Overall health rating	0.3	0.7	3.6	0.6	-0.1	-0.2	-0.4	0.6	-1.5	-0.7	-0.5	0.4	0.2	-1.9	0.5
Medication: Aspirin	0.3	0.3	1.3	0.3	0.1	0.4	0.2	-0.2	0.7	0.4	0.1	1.1	1.1	0.6	0.7
Arm fat percentage (left)	0.3	1.2	6.6	-0.1	0.6	-0.5	0.9	-0.5	-1.1	-0.2	-0.0	0.3	-1.7	1.3	2.6
Commuting to job workplace: Walk	0.3	0.4	1.0	-1.0	-0.9	0.1	-0.3	-0.1	0.0	-0.1	-0.0	-0.9	-1.0	-0.4	-0.8
Asthma (self-reported)	0.3	0.6	2.6	0.8	0.6	1.6	0.3	1.3	0.4	0.4	0.4	-0.9	-0.6	-0.5	-0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.6	1.3	-0.6	-1.1	0.8	-0.8	-0.8	-0.3	-1.0	-0.4	0.0	-0.6	1.1	0.7
Arm fat mass (left)	0.3	1.3	5.6	-0.1	0.3	-1.1	0.6	-0.8	-1.4	-0.4	-0.4	0.0	-2.1	0.8	2.4
Miserableness	0.3	0.6	1.4	1.0	0.9	0.4	0.0	-1.1	-0.2	-0.1	0.6	1.2	1.0	-0.1	0.9
Myopia	0.3	0.4	2.0	0.2	0.6	0.4	0.7	0.2	0.2	0.8	0.6	-0.6	-0.1	-0.3	-1.4
Basal cell carcinoma (self-reported)	0.3	0.3	1.2	-0.1	1.1	-0.5	0.6	-0.3	0.1	0.4	0.3	0.1	-0.7	0.8	0.5
Impedance of whole body	0.3	1.6	3.8	-0.3	-2.0	1.7	-1.8	0.5	-0.9	-1.4	-0.9	-0.9	0.8	-1.5	-1.4
Leg fat mass (left)	0.3	1.2	4.5	-0.3	0.4	-1.6	0.8	-0.6	-1.4	-0.2	-0.5	-0.5	-2.1	0.6	1.7
Neuroticism (Nagel 2018)	0.2	0.4	1.3	-0.8	-0.2	-0.1	-0.9	-0.6	-0.2	-0.4	-1.1	-0.3	-0.2	-1.1	-0.6
Mean Putamen Volume	0.2	0.2	0.6	-0.8	-0.6	-0.1	-0.3	0.3	-0.5	-0.4	-0.3	0.7	-0.1	-0.6	0.1
Heel T-Score	0.2	1.6	6.1	-0.7	-0.5	-2.5	-0.6	-1.9	-0.9	-1.0	-0.1	1.4	-0.3	0.9	2.0
Height	0.2	2.9	11.3	-1.9	-1.6	-0.5	-1.4	-1.2	0.2	-0.4	-1.2	-2.9	-0.3	-2.0	-3.4
Sensitivity / hurt feelings	0.2	0.3	0.9	0.6	0.6	-0.5	0.3	-0.6	0.1	0.3	0.4	0.9	0.2	1.0	0.6
Diabetes (father)	0.2	0.2	0.6	-0.5	0.1	-0.8	0.2	0.7	0.4	0.3	-0.0	0.4	0.5	-0.6	-0.2
Fed-up feelings	0.2	0.4	1.5	0.7	0.1	0.6	-0.3	0.5	-0.5	-0.2	-0.5	1.1	0.6	-1.2	0.3
Qualifications: CSEs or equivalent	0.2	0.2	1.1	0.3	0.3	-0.6	0.5	1.1	0.1	0.4	-0.2	-0.2	-0.2	0.3	0.3
Neuroticism score	0.2	0.3	1.4	0.1	-0.1	0.9	-0.5	0.1	-0.1	-0.3	0.1	0.7	0.9	-1.2	-0.2
Weight	0.2	1.0	4.8	-0.1	-0.0	-1.2	0.2	-0.8	-1.4	-0.4	-0.6	-0.4	-2.2	0.2	1.7
Impedance of arm (right)	0.2	1.1	5.8	-0.1	-1.0	2.4	-0.9	1.0	-0.2	-0.7	0.2	-0.4	1.2	-1.2	-1.2
Hip circumference	0.2	1.0	4.4	0.1	-0.1	0.0	-0.2	-0.6	-1.7	-0.9	-0.8	-0.4	-2.1	-0.3	1.7
Mouth/teeth dental problems: Dentures	0.2	0.3	1.7	-0.2	-0.2	1.3	-0.1	0.2	1.1	0.4	-0.1	0.1	0.5	-0.0	-0.1
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.3	1.0	0.1	-0.6	-0.6	-0.4	0.7	-0.7	-0.4	0.1	0.4	0.1	-1.0	0.0
Qualifications: College or University degree	0.2	0.6	2.8	1.2	-0.5	1.7	-0.4	0.1	0.5	-0.1	0.7	0.7	0.9	0.0	-0.7
Comparative height size at age 10	0.2	0.9	2.8	0.5	-1.7	1.2	-1.5	-0.3	-1.3	-1.1	-0.1	-0.1	-0.3	-1.1	0.4
Family relationship satisfaction	0.2	0.3	1.4	-0.0	0.7	0.2	-0.2	-0.6	0.5	0.2	0.1	-0.1	0.1	-0.9	-1.2
Average weekly red wine intake	0.2	0.3	0.7	-0.3	0.4	0.8	0.3	-0.1	0.6	0.3	0.8	-0.4	-0.3	-0.3	-0.8
Osteoarthritis (self-reported)	0.2	0.2	1.1	0.4	-0.7	0.0	-1.1	0.2	-0.2	-0.4	-0.4	-0.4	0.2	-0.4	-0.2
Mother’s age at death	0.2	0.3	0.9	-0.7	-0.5	-0.4	-0.0	0.6	-0.6	-0.2	-0.0	-0.2	0.9	-0.7	-0.8
Supplements: Calcium	0.2	0.2	0.7	0.7	0.3	-0.1	0.2	0.8	0.2	0.3	0.7	0.0	0.2	-0.2	-0.7
Arm predicted mass (left)	0.2	0.8	3.6	0.2	0.0	-1.9	0.0	-1.2	-0.9	-0.2	-0.4	-0.0	-1.4	-0.1	1.0
Depressed Affect (Nagel 2018)	0.1	0.3	1.5	0.7	0.0	-0.0	-0.5	-0.6	0.1	-0.2	-0.3	1.2	0.7	-0.4	0.1
Rheumatoid Arthritis	0.1	0.2	0.8	-0.4	0.2	-0.9	0.1	0.0	0.3	0.2	0.0	0.5	0.5	0.4	0.5
Blood Eosinophil Count	0.1	1.1	4.4	-0.6	0.8	-2.1	1.1	0.5	-0.2	0.4	0.3	-1.5	-1.3	-0.8	-1.1
Blood Platelet Count	0.1	1.5	8.7	-1.6	0.1	0.2	1.1	0.9	-0.8	-0.0	-0.3	-1.4	-3.0	0.5	1.4
Hearing difficulty/problems: Yes	0.1	0.2	0.4	0.1	-0.2	-0.5	0.5	-0.6	-0.0	0.5	0.1	-0.7	-0.6	-0.5	-0.4
Leg fat-free mass (left)	0.1	0.4	2.8	0.1	0.2	-0.6	0.3	0.1	-0.6	0.0	-0.1	-0.2	-1.7	-0.3	1.1
Hayfever, allergic rhinitis or eczema	0.1	0.3	1.0	0.5	0.5	-0.8	0.1	-0.6	-0.8	0.0	0.4	0.3	-0.7	0.2	1.0
Sitting height	0.1	0.5	1.3	0.4	-0.7	-0.1	-0.5	-0.2	0.4	0.1	0.9	-1.1	-0.4	-1.1	-1.0
Leg predicted mass (left)	0.1	0.4	2.3	0.3	0.2	-0.6	0.3	0.1	-0.6	-0.0	-0.0	-0.0	-1.5	-0.1	1.2
Nervous feelings	0.1	0.3	0.8	-0.5	0.1	0.3	-0.4	-0.9	0.7	0.1	-0.1	-0.5	-0.7	-0.5	-0.6
Qualifications: None of the above	0.1	0.3	1.1	-1.0	-0.1	-1.1	0.4	0.1	0.1	0.5	-0.8	0.0	-0.5	0.5	0.4
Allergy	0.1	0.3	1.5	-0.7	-0.4	0.3	-0.1	-0.1	0.5	-0.0	-0.5	0.7	1.2	0.5	-0.2
Fluid intelligence score	0.1	0.2	0.7	-0.8	0.7	-0.1	0.4	-0.2	-0.0	0.2	0.6	-0.6	-0.2	-0.0	-0.5
Trunk fat-free mass	0.1	0.4	2.3	0.2	0.5	-1.1	0.4	-0.6	-0.2	0.4	0.3	-0.5	-1.5	0.0	0.4
Trunk predicted mass	0.1	0.5	2.5	0.1	0.4	-1.2	0.3	-0.7	-0.3	0.3	0.2	-0.5	-1.6	-0.1	0.5
Standing height	0.1	1.4	3.7	0.1	-1.7	1.0	-1.5	-0.4	-0.1	-0.6	-0.4	-1.9	-0.9	-1.7	-1.7
Birth weight	0.1	0.3	0.9	-0.4	-0.3	-0.1	-0.8	0.8	-0.3	-0.3	-0.7	-0.0	-0.9	0.1	0.7
Arm fat-free mass (right)	0.1	0.7	3.4	0.2	0.0	-1.5	0.2	-0.8	-1.0	-0.1	-0.5	-0.4	-1.9	0.1	1.0
Arm predicted mass (right)	0.1	0.5	3.1	0.4	0.2	-1.2	0.5	-0.5	-0.6	0.3	-0.2	-0.4	-1.8	0.1	0.8
Whole body fat-free mass	0.1	0.5	2.7	0.2	0.3	-1.2	0.3	-0.6	-0.4	0.2	0.0	-0.3	-1.6	-0.0	0.8
Leg fat-free mass (right)	0.1	0.4	3.1	0.4	0.1	-0.6	0.2	-0.4	-0.2	0.2	0.1	-0.0	-1.8	0.1	1.1
Whole body water mass	0.1	0.4	2.7	0.1	0.3	-1.1	0.4	-0.5	-0.3	0.3	0.1	-0.3	-1.6	0.1	0.8
Leg predicted mass (right)	0.1	0.4	3.0	0.4	0.2	-0.6	0.2	-0.3	-0.1	0.2	0.1	0.0	-1.7	0.1	1.2
Basal metabolic rate	0.1	0.6	2.9	0.2	0.2	-1.1	0.2	-0.6	-0.7	-0.0	-0.1	-0.1	-1.7	-0.0	1.2
Arm fat-free mass (left)	0.1	0.6	2.5	0.2	0.1	-1.6	0.3	-0.9	-0.7	0.1	-0.2	-0.2	-1.6	0.1	1.1
Hair Pigment	0.0	1.0	5.8	-1.2	0.5	0.1	0.4	1.2	0.8	-0.2	-0.3	-2.4	-1.0	0.1	-1.1

Hub : Genes

FZD6

Models

Trait associations