Hub : Genes

GALNT10

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0800 0.0270 5.1e-05 0.012 0.038 0.012 0.037 0.023 1.0e-02 1.6e-05 1.1e-02 2.1e-05 7.0e-04
2 GTEx Adipose Visceral Omentum 0.1380 0.0460 1.3e-04 0.100 NA 0.110 NA 0.114 7.3e-06 NA 2.6e-06 NA 1.7e-06
3 GTEx Artery Aorta 0.2300 0.0710 2.3e-03 0.016 NA 0.007 NA 0.031 4.2e-02 NA 1.3e-01 NA 7.7e-03
4 GTEx Brain Caudate basal ganglia 0.3050 0.1070 5.0e-03 0.070 NA 0.108 NA 0.104 4.6e-03 NA 5.1e-04 NA 6.6e-04
5 GTEx Colon Transverse 0.1710 0.0590 9.4e-04 0.125 NA 0.034 NA 0.089 1.5e-06 NA 1.0e-02 NA 4.9e-05
6 GTEx Esophagus Muscularis 0.2320 0.0650 1.7e-05 0.107 NA 0.079 NA 0.090 4.9e-07 NA 1.6e-05 NA 4.1e-06
7 GTEx Heart Atrial Appendage 0.2200 0.0670 1.2e-04 0.204 NA 0.178 NA 0.200 1.6e-09 NA 2.1e-08 NA 2.4e-09
8 GTEx Lung 0.0648 0.0288 9.2e-03 -0.002 NA -0.001 NA -0.001 4.5e-01 NA 3.6e-01 NA 4.0e-01
9 GTEx Ovary 0.5570 0.1270 5.5e-05 0.255 NA 0.207 NA 0.269 5.8e-07 NA 8.0e-06 NA 2.5e-07
10 GTEx Skin Sun Exposed Lower leg 0.0860 0.0310 7.5e-04 0.057 NA 0.041 NA 0.053 1.6e-05 NA 2.2e-04 NA 3.5e-05
11 GTEx Thyroid 0.1130 0.0380 5.5e-04 0.085 NA 0.094 NA 0.101 4.6e-07 NA 1.2e-07 NA 4.0e-08
12 METSIM Adipose 0.1252 0.0296 1.4e-11 0.078 0.081 0.088 0.084 0.076 1.1e-11 3.3e-12 3.6e-13 1.3e-12 1.6e-11
13 ROSMAP Brain Pre-frontal Cortex 0.0587 0.0260 5.4e-03 0.003 0.011 -0.001 0.009 0.004 1.2e-01 1.3e-02 4.8e-01 2.0e-02 9.4e-02
14 TCGA Head and Neck Squamous Cell Carcinoma 0.0771 0.0335 5.6e-03 -0.002 0.028 0.014 NA -0.002 9.6e-01 3.5e-04 9.6e-03 NA 9.7e-01
15 TCGA Brain Lower Grade Glioma 0.0735 0.0285 1.5e-04 0.008 0.041 0.030 NA 0.004 3.3e-02 1.7e-05 2.0e-04 NA 1.2e-01
16 TCGA Prostate Adenocarcinoma 0.0838 0.0330 7.5e-05 0.057 0.035 0.031 NA 0.042 1.2e-06 1.4e-04 2.8e-04 NA 3.3e-05
17 TCGA Thyroid Carcinoma 0.1290 0.0360 3.2e-07 0.054 0.092 0.065 NA 0.059 5.8e-06 3.2e-09 6.2e-07 NA 2.2e-06

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17
Bipolar Disorder (2018) 1.1 1.7 6.1 -0.5 -0.7 2.5 0.6 -1.2 -2.1 -0.7 -1.0 1.5 -0.1 1.4 -1.1 -1.2 -0.5 0.5 1.7 1.9
Bipolar Disorder or Schizophrenia 2.5 6.0 17.2 2.9 1.4 -0.0 4.1 -1.2 -2.6 2.0 -1.0 -1.0 3.0 4.1 0.8 1.8 0.7 3.2 -1.7 4.1
Depressed Affect (Nagel 2018) 1.8 3.9 11.8 2.2 2.6 -1.2 3.4 -0.6 0.7 2.6 0.6 -1.6 2.9 1.7 2.3 1.6 1.9 0.8 -1.5 2.2
Depression (Nagel 2018) 2.3 3.5 12.5 1.4 1.5 0.4 3.5 -1.9 -0.5 2.1 -0.6 -0.6 2.2 2.8 1.8 2.4 2.0 0.7 -0.8 2.6
Intelligence (Savage-Jansen 2018) 1.3 4.0 9.8 1.1 2.5 -1.9 1.1 2.3 3.0 2.2 2.0 -3.1 2.1 -1.1 2.1 1.2 1.1 1.6 -2.3 -1.2
Neuroticism (Nagel 2018) 3.3 7.8 19.2 3.4 2.2 -1.0 3.8 -2.3 -1.9 2.9 -0.8 -1.6 3.5 4.3 1.9 2.3 3.8 1.8 -2.3 4.4
Schizophrenia (2018) 4.5 9.4 23.7 4.1 2.4 -2.0 4.9 -0.5 -1.6 3.1 -0.5 -2.5 4.0 4.1 2.1 3.2 1.4 3.7 -3.6 3.8
Schizophrenia vs Biploar Disorder 2.4 3.2 10.8 1.9 1.7 -2.0 2.1 1.3 0.3 1.8 0.9 -3.3 2.4 1.2 1.4 1.4 -0.2 1.6 -2.5 1.3
Worry (Nagel 2018) 3.2 6.7 20.2 3.1 1.5 -0.9 3.0 -2.2 -2.7 2.2 -1.3 -1.3 3.3 4.5 1.0 0.9 3.5 2.1 -2.1 4.2
Alzheimer’s Disease (in mother) 1.5 1.7 8.7 1.0 0.2 -1.0 0.3 -1.4 -0.6 0.7 -0.1 -0.5 0.8 1.7 0.8 1.8 3.0 0.8 -2.1 1.7
Alzheimer’s Disease (in father) 3.1 3.3 13.9 2.0 0.6 -1.3 0.7 -1.4 -1.3 1.6 -0.3 -1.8 1.3 2.8 1.1 2.1 2.4 1.9 -3.7 1.5
Alzheimer’s Disease (including proxy) 3.7 5.4 19.7 2.6 1.6 -2.6 1.7 -0.5 -0.3 2.3 0.8 -2.7 2.4 2.7 1.7 2.6 2.8 2.2 -4.4 1.9
Crohns Disease (2017) 0.1 0.2 1.1 -0.2 0.2 0.0 0.2 0.5 -0.6 0.2 0.6 0.1 0.4 0.5 -0.5 -0.8 -0.2 -1.1 0.1 0.7
Irritable Bowel Disease (IBD) 0.7 1.7 6.1 0.4 1.3 -0.7 0.8 2.4 0.7 0.7 2.5 -0.6 1.3 -1.1 -0.1 -2.1 -2.1 -0.7 0.3 -0.9
Ulcerative Colitis (UC) 1.7 3.3 11.0 0.6 1.9 -0.7 1.1 2.9 1.6 1.2 3.2 -0.8 1.6 -2.0 0.5 -2.5 -3.3 -0.1 0.3 -1.8
Major Depression (MDD) 0.4 0.5 2.0 -0.9 -0.3 0.2 0.2 -1.1 -0.5 -0.2 -0.6 1.0 -0.4 0.7 -0.6 1.4 0.9 0.0 0.9 0.8
Reaction Time 0.8 1.5 4.7 -1.4 1.0 -1.6 -0.7 1.5 2.2 0.4 1.3 -0.7 0.6 -1.6 1.3 0.9 -0.1 -1.3 0.7 -1.4
Verbal and Numeric Reasoning (VNR) 0.8 1.9 8.2 0.6 0.9 -1.9 -0.5 1.9 2.9 0.5 1.4 -1.1 0.4 -2.2 1.2 0.9 1.1 0.2 -0.4 -1.8
Breast Cancer 0.4 0.9 3.2 -0.9 -1.0 -0.4 -1.8 -0.1 -0.2 -1.1 -0.9 1.0 -0.9 -0.6 -1.5 -0.1 0.1 -1.6 -0.3 -0.9
Ovarian Cancer 0.1 0.2 0.4 -0.1 -0.5 0.6 0.3 -0.0 -0.5 -0.4 -0.5 0.1 -0.1 -0.4 -0.6 0.0 0.6 0.5 0.0 -0.5
Prostate Cancer 0.9 1.3 5.3 1.0 0.7 -0.6 1.5 -0.6 -0.8 1.1 -0.5 -0.8 0.8 1.0 0.9 0.9 2.3 1.4 -0.8 1.8
Age at First Birth 0.2 0.3 1.2 0.5 -0.0 -1.1 0.7 0.3 0.4 0.1 0.6 -0.2 -0.4 -0.7 -0.3 -1.0 0.0 0.3 -0.2 -1.1
Bipolar Disorder (2011) 0.6 0.6 3.1 -1.0 0.5 1.5 0.0 -0.1 0.0 0.1 -0.2 0.8 0.5 0.3 0.3 -0.7 -1.0 0.7 1.8 0.7
Body Mass Index (BMI) (2010) 3.7 5.0 22.2 -3.0 -2.6 1.3 -4.7 -2.0 -0.9 -2.6 -1.6 2.9 -2.6 -0.1 -1.7 -1.7 0.5 -2.2 2.2 0.6
Coronary Artery Disease (CAD) 0.3 0.4 2.0 0.4 0.5 0.1 -0.3 0.2 0.9 0.5 1.1 -0.6 0.1 -0.9 1.4 0.2 -0.9 -0.1 -0.5 -0.3
Crohns Disease (2012) 0.3 0.4 2.8 -0.3 0.2 -0.3 -1.7 0.5 0.8 0.1 0.7 -0.1 -0.1 -1.0 0.4 0.2 -0.2 -1.0 0.0 -0.6
Mean Putamen Volume 0.3 0.4 1.5 -0.0 -0.0 -1.2 0.6 0.2 0.6 0.1 -0.4 -0.4 -0.2 -0.7 -0.6 0.3 1.2 -0.6 -0.3 -1.0
Fasting Glucose 2.1 2.5 9.2 -1.8 -1.1 1.5 -1.6 -1.2 0.6 -1.6 -1.3 2.3 -1.5 -1.2 -0.4 -1.5 -1.6 -1.8 3.0 -0.7
HbA1C 0.4 0.5 2.5 0.9 0.5 -0.1 1.1 0.9 -0.4 0.5 1.4 -0.1 0.5 0.1 0.2 -1.6 0.4 -0.1 -0.1 -0.4
HDL Cholesterol 0.3 0.6 6.0 0.9 -0.0 0.5 0.3 -0.1 -0.0 0.1 -1.1 -0.3 0.0 -0.4 0.5 2.4 -0.3 0.2 -0.8 0.3
LDL Cholesterol 0.4 0.7 2.3 0.9 -0.7 1.1 0.2 -0.7 -1.1 -0.6 -0.1 0.6 0.1 1.1 -1.0 -1.5 -0.3 -0.7 0.6 1.0
Lupus 1.4 2.2 7.1 2.7 1.5 -1.1 1.3 0.8 0.4 1.6 0.4 -1.3 1.5 0.6 1.8 2.2 -0.2 1.6 -2.1 1.3
Neuroticism (2016) 1.2 1.7 4.2 1.5 -0.5 1.6 1.7 -1.6 -2.0 0.1 -2.0 0.9 0.4 1.7 -0.3 1.4 1.2 -0.2 0.4 1.5
Primary Biliary Cirrhosis 1.1 1.6 4.5 -1.0 -1.9 -0.0 -1.5 -0.9 -0.8 -2.0 -0.9 1.5 -1.6 -0.2 -0.8 -2.1 0.8 -0.8 1.4 -0.1
Rheumatoid Arthritis 0.3 0.4 1.6 -1.3 -0.3 0.7 0.1 -0.6 -0.9 -0.1 -0.2 -0.1 -0.1 0.9 -0.5 0.5 -0.9 0.1 -0.6 0.9
Schizophrenia (2014) 2.7 5.9 13.6 3.2 1.2 -1.3 3.4 -1.1 -2.0 1.9 -1.2 -1.5 2.5 3.7 1.1 2.7 1.6 3.4 -2.8 3.6
Triglycerides 0.2 0.4 1.5 -0.1 -0.2 0.8 -0.5 -1.0 -0.7 0.2 -0.3 0.5 0.0 1.2 0.1 -0.1 1.0 -0.0 0.3 1.1
Type 2 Diabetes (T2D) (2012) 3.4 3.9 8.9 -2.1 -3.0 -0.2 -1.6 -1.2 -1.2 -2.9 -0.9 2.5 -2.5 -0.5 -2.6 -2.0 -1.7 -2.0 2.6 -0.9
Ulcerative Colitis 1.4 2.0 8.1 0.3 1.0 0.2 0.1 2.0 1.4 0.5 2.6 -0.7 0.9 -1.5 0.1 -2.4 -2.9 0.4 0.0 -1.4
Blood Eosinophil Count 0.0 0.2 1.3 -0.2 0.3 -0.4 0.3 0.2 0.1 -0.3 0.2 -0.2 0.1 0.4 0.5 -0.1 0.9 -1.1 0.7 -0.5
Blood Platelet Count 0.1 0.9 4.1 -0.0 0.3 0.1 0.9 -0.5 1.5 0.1 -1.3 0.3 -0.9 -0.6 0.9 2.0 -1.3 0.2 1.2 0.5
Blood Red Count 0.3 2.7 14.4 3.8 0.7 -0.4 2.8 -1.1 -1.1 1.2 0.8 -0.9 0.8 2.4 1.4 0.8 1.0 0.5 -1.6 2.3
Blood White Count 0.4 2.6 6.1 0.9 2.5 -1.8 1.9 1.0 1.2 2.4 2.0 -2.0 2.3 1.4 1.7 0.2 0.7 1.1 -1.0 1.2
Heel T-Score 0.4 3.2 8.0 1.7 -2.6 1.9 -0.9 -2.8 -2.8 -1.7 -1.4 1.3 -1.2 2.8 -2.0 1.1 0.1 1.0 -0.6 1.2
BMI 2.7 16.0 43.0 -6.1 -5.3 1.8 -6.6 -3.9 -2.4 -5.1 -1.1 3.9 -5.2 0.1 -4.3 -4.3 2.2 -4.5 2.6 1.3
Height 0.1 1.8 4.7 1.8 1.4 0.0 -0.5 0.1 -0.0 1.9 1.6 -1.3 1.3 1.5 1.4 1.0 2.1 0.4 -2.2 0.9
Waist Hip Ratio (WHR) 0.4 1.6 4.5 -2.1 1.2 -1.9 0.3 1.4 1.8 0.4 1.0 -0.7 0.7 -2.1 0.3 -0.3 -1.2 -0.5 1.5 -1.3
Systolic Blood Pressure 0.3 1.7 4.4 1.8 1.7 -0.0 2.1 1.4 2.1 1.5 0.2 -1.6 0.9 -1.0 1.3 0.3 -1.5 1.2 -0.3 -0.4
Smoking Status 0.1 0.3 0.9 -0.9 0.8 -0.1 0.3 0.4 -0.0 0.8 -0.2 -0.3 0.9 0.1 0.3 -0.1 0.5 -0.7 0.2 -0.2
Allergy or Eczema 0.2 0.4 2.1 -1.1 -0.4 1.4 -0.8 0.4 -0.9 -0.5 0.1 -0.3 0.0 -0.4 -0.4 -0.4 0.7 -0.7 -0.0 -0.8
Cardiovascular Disease 0.8 2.7 15.3 -3.9 -1.0 0.6 -1.5 -0.2 0.7 -1.7 0.4 0.8 -1.5 -1.6 -0.7 -2.1 -0.1 -2.6 2.4 -0.8
Hypothyroidism (self reported) 0.1 0.2 1.0 0.2 0.0 0.6 0.7 -0.4 -0.2 -0.0 -0.5 -0.4 -0.4 0.1 -0.1 0.1 -0.2 0.2 0.1 1.0
Respiratory disease 0.9 2.1 4.9 0.7 1.7 0.3 2.2 -0.0 -0.1 2.1 0.6 -1.1 2.1 2.2 1.3 -0.5 0.2 2.2 -0.5 2.1
Type 2 Diabetes (T2D) (2018) 0.5 1.0 5.0 -2.0 -0.4 0.5 -2.2 -0.7 0.2 -0.6 0.5 0.6 -0.9 -0.2 0.1 -1.1 0.3 -1.1 1.5 -0.1
Lung FEV1/FVC ratio 0.3 1.3 3.9 -1.2 -1.3 1.4 -1.6 0.3 -0.3 -1.5 0.6 0.7 -1.3 -1.0 -0.8 -1.1 -2.0 -0.7 1.5 -0.3
Lung FVC 0.4 2.0 7.1 0.3 -1.1 2.2 0.8 -0.2 0.3 -1.5 -2.2 1.3 -1.4 -1.4 -0.7 0.2 -2.7 -1.0 2.2 -1.4
Neuroticism 2.3 5.5 11.8 2.9 2.8 -0.8 3.3 -1.0 -0.1 3.2 -0.3 -1.0 3.4 2.7 2.6 1.7 3.1 1.2 -1.3 3.4
Chronotype (morning person) 0.2 0.4 1.3 0.2 -0.9 -0.2 0.6 -0.9 -1.1 -0.8 -1.1 -0.1 -0.4 0.6 -0.9 -0.1 -0.1 0.2 -0.4 0.8
Hair Pigment 0.0 0.9 6.6 0.1 -0.8 0.4 -2.6 -0.9 -0.4 -0.8 -0.7 1.1 -1.4 -0.5 -0.2 -0.6 1.2 -0.6 0.6 -0.0
Tanning 0.2 2.7 5.2 -2.2 -2.0 1.3 -0.8 -2.0 -2.3 -2.0 -1.9 1.9 -0.9 1.4 -2.1 0.2 -0.2 -1.2 1.9 1.4
Hand grip strength (left) 0.6 1.7 5.4 1.7 -0.2 0.8 2.3 -1.2 -1.6 0.4 -1.2 -0.2 0.6 2.1 -1.2 -0.1 0.7 1.2 -1.0 2.2
Number of treatments/medications taken 0.9 1.7 6.6 -2.2 1.1 -0.2 1.2 0.5 0.9 0.8 1.8 -1.1 0.9 -0.0 0.1 -2.6 -1.4 -1.0 1.8 1.1
Average weekly spirits intake 1.1 1.3 3.9 -1.7 -1.5 0.5 -1.7 -0.6 -1.3 -1.5 -0.9 0.6 -1.0 0.2 -1.6 -2.0 -0.2 -0.6 1.1 0.3
Sensitivity / hurt feelings 2.0 3.4 8.4 2.3 2.0 -0.4 2.9 0.1 -1.0 2.5 0.9 -2.3 2.9 1.9 1.2 1.3 0.7 2.0 -1.7 1.9
Frequency of depressed mood in last 2 weeks 1.5 2.1 7.4 1.1 2.1 -0.2 2.7 0.1 -0.1 2.1 0.2 -1.1 2.6 1.8 1.2 1.5 1.3 0.4 -0.5 0.9
Hearing difficulty/problems: Yes 0.7 1.0 6.7 -2.6 0.2 1.1 -0.7 -0.2 0.2 0.2 1.8 -0.2 0.1 -0.1 0.1 -1.9 -1.2 0.4 0.6 0.4
Relative age of first facial hair 1.9 3.9 12.5 1.6 2.9 -1.6 0.7 2.1 3.3 2.5 1.8 -1.9 2.0 -1.8 3.5 0.2 1.3 0.4 -1.1 -0.5
Other serious medical condition/disability diagnosed by doctor 0.3 0.4 2.3 -1.5 0.0 0.6 -1.2 -0.3 0.8 0.0 0.2 -0.2 0.1 0.2 0.5 -0.7 0.9 -0.0 0.7 -0.2
Ever used hormone-replacement therapy (HRT) 2.8 3.5 12.7 1.2 2.6 -0.8 0.2 2.7 1.8 2.3 3.6 -2.4 3.1 0.2 2.2 -0.6 -0.3 0.9 -0.8 -1.1
Ever had hysterectomy (womb removed) 3.2 3.6 9.6 0.9 2.3 -0.2 1.9 1.3 0.7 2.3 2.7 -3.1 2.5 0.8 1.8 -1.8 -1.7 2.8 -1.7 -0.2
Systolic blood pressure, automated reading 0.2 0.5 2.1 -0.2 -0.4 0.5 -0.5 -0.3 0.5 -0.5 -0.6 0.6 -0.9 -0.4 -0.3 -0.3 -1.4 -0.9 1.3 0.0
Eye problems/disorders: Diabetes related eye disease 0.6 0.7 2.1 -1.0 0.7 -1.2 -0.0 0.9 1.4 0.4 0.8 -0.9 0.2 -1.0 1.2 0.7 0.1 -0.3 -0.1 -1.2
Angina 0.4 0.5 1.6 -0.3 0.4 -1.2 -1.1 0.8 1.2 -0.1 1.2 -0.3 0.1 -0.9 0.3 -0.1 -0.0 -1.0 -0.1 0.0
Medication for hormone replacement therapy 1.7 1.9 8.3 0.7 1.8 -1.1 1.2 2.9 1.1 1.3 1.3 -1.6 2.3 -0.7 0.8 0.3 -0.9 0.2 -0.8 -1.6
Vitamin and mineral supplements 0.8 1.1 3.8 -0.8 -1.5 -0.4 -0.1 -1.0 -0.3 -1.2 -1.7 1.2 -1.9 -0.2 -1.9 -0.6 0.4 0.3 -0.5 -0.1
Supplements: Zinc 2.4 2.6 6.8 -1.0 -2.5 1.4 -1.1 -2.3 -1.3 -2.3 -1.8 2.6 -2.3 0.0 -1.6 -0.1 0.1 -1.2 1.2 -0.3
Medication: Co-codamol 0.6 0.7 1.5 -0.2 1.2 -1.0 1.2 0.8 0.6 0.9 1.2 -1.0 1.2 0.1 0.6 -0.5 -0.8 0.3 0.1 0.6
Medication: Metformin 0.5 0.7 4.2 -0.9 0.6 0.5 -0.7 0.0 2.1 0.3 1.0 0.1 -0.5 -1.2 1.1 -0.2 -0.9 -0.3 0.2 -0.2
Diabetes (father) 0.6 0.7 3.2 -1.4 -0.7 -0.5 -1.8 -0.3 -0.6 -0.7 -0.2 0.4 -0.4 0.0 -1.1 -1.1 1.5 0.1 0.3 -0.0
Diabetes (mother) 0.3 0.3 1.3 0.1 0.3 -0.8 -0.3 0.5 -0.9 0.4 1.1 -0.8 0.5 0.6 -0.0 0.0 -1.1 -0.2 -0.3 0.2
Severe depression (siblings) 0.9 1.0 6.2 0.7 0.6 -0.3 1.6 -0.3 -1.2 0.9 -0.5 -0.4 1.1 1.5 0.6 1.0 -0.2 -0.2 -0.6 2.5
Pack years adult smoking proportion 1.7 2.6 14.8 -3.8 -1.4 0.5 -1.6 -1.0 -0.5 -1.8 -0.5 1.4 -1.9 -0.7 -1.1 -2.0 -0.5 -1.7 2.2 0.5
Impedance of leg (right) 0.5 2.2 8.9 1.1 1.7 0.1 1.6 2.6 1.1 1.0 -0.0 -0.4 1.3 -1.6 1.1 1.1 -3.0 -0.1 1.1 -2.2
Leg fat-free mass (left) 0.4 2.3 7.6 -2.0 -0.9 -0.2 -2.8 -2.6 -0.6 -0.2 1.1 0.1 -1.0 1.4 -0.0 -1.4 2.4 -0.6 -0.7 2.8
Trunk fat percentage 1.2 5.0 20.5 -4.5 -2.1 -0.2 -4.5 -1.8 -0.3 -2.0 0.2 1.5 -2.6 -0.4 -1.4 -2.4 0.5 -3.2 2.0 0.4
Hand grip strength (right) 0.6 1.7 6.5 2.1 0.7 -0.3 2.5 -0.5 -1.2 1.0 -0.5 -0.8 1.2 2.0 -0.4 -0.5 -0.3 1.0 -1.3 2.1
Townsend deprivation index at recruitment 0.7 1.0 4.9 -2.2 0.3 -0.7 1.0 -0.4 0.6 -0.1 -0.1 0.4 -0.2 -0.4 0.3 0.3 -1.5 -1.3 2.2 0.2
Current tobacco smoking 0.2 0.4 1.4 -0.6 0.6 0.1 0.8 0.4 -0.8 0.4 0.5 -0.8 1.2 0.6 -0.5 -0.6 -0.0 -0.2 0.5 0.6
Average weekly fortified wine intake 0.7 0.8 3.1 -0.3 -0.6 -0.6 0.2 0.4 -0.4 -0.9 0.1 0.6 -0.9 -1.1 -0.2 1.1 -1.8 -1.4 1.0 -1.7
Maternal smoking around birth 1.0 1.5 5.4 -0.4 2.2 -0.7 1.7 -0.2 0.8 2.3 0.8 -0.6 1.4 1.0 1.9 0.6 0.2 0.9 -0.4 1.5
Fed-up feelings 2.0 3.7 8.1 1.7 2.4 -1.1 2.7 -0.1 0.7 2.6 1.1 -2.2 2.9 1.7 2.5 1.6 1.1 1.5 -1.9 2.2
Frequency of unenthusiasm / disinterest in last 2 weeks 0.7 0.9 5.1 -0.4 1.0 -0.3 2.3 -0.6 0.3 1.1 0.1 -0.3 1.2 1.1 0.9 1.1 0.7 -0.4 0.7 1.3
Relative age voice broke 1.9 2.9 9.7 -0.8 1.5 -0.9 -1.1 3.1 2.9 0.6 2.2 -1.5 0.8 -3.0 0.9 -1.1 0.1 -1.4 -0.1 -2.1
Taking other prescription medications 0.7 1.1 4.7 -1.3 1.1 -1.5 -0.3 1.1 1.0 0.7 2.2 -0.8 1.2 -0.3 0.7 -1.5 -0.0 -1.1 0.7 -0.3
Age when periods started (menarche) 0.3 0.6 2.4 -0.4 0.2 0.3 1.4 0.9 0.3 -0.3 -0.5 0.6 0.4 -1.2 -0.5 0.1 -1.5 -0.7 1.2 -0.8
Bilateral oophorectomy (both ovaries removed) 1.2 1.4 4.7 2.2 1.1 -0.8 0.5 1.1 0.6 1.0 1.1 -2.0 1.0 0.1 0.5 0.4 -1.0 1.7 -1.7 -0.7
Heel bone mineral density (BMD) T-score, automated (left) 0.3 0.7 3.9 -0.0 -1.0 2.0 -1.5 -0.4 0.5 -0.9 -0.1 0.8 -0.8 0.0 -0.9 -0.7 -0.6 -0.5 0.8 -0.6
Tinnitus: Yes, but not now, but have in the past 0.2 0.2 1.4 0.1 -0.1 0.1 1.2 -0.7 -0.2 0.1 -0.2 0.4 -0.1 0.3 -0.1 0.2 -0.1 0.0 -0.6 0.4
Qualifications: CSEs or equivalent 0.4 0.5 1.4 -0.9 0.6 0.0 -1.2 0.4 1.1 0.1 0.4 0.3 0.1 -1.0 0.8 -0.8 -1.0 -0.5 0.8 0.5
Serious illness, injury or assault to yourself 0.6 0.7 4.0 -2.0 -0.3 -1.1 -0.5 0.6 1.1 -0.6 0.5 0.5 0.1 -1.1 -0.8 -0.8 -0.4 -1.2 0.2 -0.7
High blood pressure 0.6 1.6 8.1 -2.9 -0.2 0.5 -0.7 0.1 0.7 -0.6 0.9 0.3 -0.7 -0.6 -0.4 -2.6 -0.7 -1.6 2.4 -0.2
Hayfever, allergic rhinitis or eczema 0.3 0.6 3.5 -1.9 -0.6 1.0 -1.2 -0.1 -0.8 -0.7 -0.2 0.4 -0.6 -0.3 -0.4 -0.5 0.6 -0.8 0.4 -0.4
Multivitamins +/- minerals 0.7 0.9 2.9 1.5 0.1 1.5 0.7 -0.6 -1.3 0.1 0.2 -0.3 1.0 1.7 0.5 0.1 0.4 -0.2 0.9 1.7
Stomach or abdominal pain in last month 1.1 1.4 7.6 1.6 0.7 -1.0 1.3 -0.9 -0.2 1.0 0.9 -0.4 0.9 1.9 0.3 -0.1 2.8 -0.7 -1.0 1.4
Supplements: Glucosamine 0.7 0.9 3.1 -1.0 -1.1 1.3 -0.9 -1.8 -0.9 -0.7 -0.8 1.6 -0.7 0.5 -0.3 0.6 0.8 -0.4 0.4 0.5
Diverticular disease/diverticulitis (self-reported) 1.5 1.8 6.4 1.3 1.6 -0.2 2.5 1.0 0.1 1.8 1.6 -1.6 2.0 0.7 0.7 -0.1 -0.6 1.2 -1.4 1.1
Medication: Atenolol 0.2 0.2 0.9 -0.9 -0.3 0.2 -0.1 -0.1 -0.6 -0.3 -0.1 -1.0 0.2 0.6 -0.3 0.2 -0.1 -0.4 0.3 0.5
Medication: Levothyroxine sodium 0.3 0.6 3.5 0.3 0.4 -0.1 1.9 -0.4 -0.3 0.5 -0.2 -1.0 0.4 0.9 0.4 0.3 1.6 0.1 -0.3 0.7
Sitting height 0.2 1.2 3.3 0.1 1.5 -0.6 -0.4 -0.6 0.9 1.8 1.0 -1.2 1.2 0.7 1.5 0.3 0.9 1.4 -1.6 1.1
Chronic bronchitis/emphysema (father) 1.5 1.8 7.1 1.4 1.4 -0.3 1.6 -1.0 0.7 1.9 0.1 -0.5 0.6 1.4 2.2 1.0 0.3 1.2 -1.4 2.7
High blood pressure (mother) 0.5 0.7 2.2 -1.1 -0.3 0.7 0.9 0.5 -0.8 -0.5 0.5 0.1 -0.0 -0.4 -1.2 -1.3 -0.1 -1.5 0.5 -1.0
Body mass index (BMI) 1.2 5.2 17.3 -3.9 -2.5 0.5 -4.2 -2.5 -0.5 -2.4 0.3 1.5 -2.9 0.4 -1.8 -2.9 1.0 -2.6 1.6 1.8
Impedance of leg (left) 0.4 1.9 7.3 1.0 1.6 -0.0 1.7 2.3 0.7 1.0 -0.1 -0.7 1.5 -1.2 1.0 1.4 -2.7 0.2 0.6 -2.1
Leg predicted mass (left) 0.4 2.3 7.7 -2.0 -0.8 -0.2 -2.7 -2.6 -0.6 -0.2 1.1 0.0 -1.0 1.4 0.1 -1.3 2.3 -0.7 -0.7 2.8
Trunk fat mass 1.2 5.1 20.3 -4.3 -2.1 0.0 -4.5 -2.5 -0.6 -1.9 0.4 1.4 -2.6 0.2 -1.4 -2.3 1.3 -3.1 1.6 1.3
Waist circumference 1.1 3.9 16.7 -4.1 -1.6 0.2 -4.1 -2.3 0.1 -1.6 0.5 1.2 -2.1 0.0 -0.8 -2.3 0.8 -2.5 1.7 1.3
Number of incorrect matches in round 0.3 0.6 2.3 -1.2 0.1 0.4 1.1 0.4 -1.5 0.2 0.1 -0.4 1.2 1.5 -0.3 -0.4 0.5 0.2 0.2 0.1
Past tobacco smoking 0.4 0.7 1.9 0.2 -1.2 0.5 -0.4 -0.5 -0.5 -1.4 -0.1 1.0 -1.3 -0.8 -1.0 0.7 -1.1 -0.6 1.0 -0.6
Alcohol usually taken with meals 1.7 2.7 12.3 2.2 -0.3 0.7 1.2 -2.3 -1.8 0.4 -2.1 1.3 0.1 2.6 0.4 0.5 3.5 0.9 -1.4 1.4
Nervous feelings 2.1 3.9 11.3 2.7 0.9 -1.5 1.9 -1.4 -2.3 1.3 -1.6 -0.8 2.2 3.3 0.2 0.0 2.1 2.3 -1.6 3.4
Frequency of tenseness / restlessness in last 2 weeks 4.3 6.7 15.4 1.7 3.2 -1.7 3.9 0.1 -0.2 3.5 1.0 -2.7 3.8 2.8 3.4 2.4 2.8 0.9 -2.2 3.1
Hearing difficulty/problems with background noise 0.8 1.3 6.9 -1.1 -0.2 0.7 0.4 -2.2 -0.9 0.6 -0.3 0.5 0.0 1.9 -0.1 -0.5 1.4 1.1 0.2 2.6
Hair/balding pattern: Pattern 2 3.1 3.9 10.8 2.7 2.5 0.2 0.8 2.0 1.6 2.4 1.6 -2.3 2.3 -0.3 3.3 2.9 -0.6 2.1 -1.3 -1.2
Had menopause 0.4 0.4 1.5 -0.3 0.6 -0.8 0.7 0.4 -0.1 0.7 1.2 -0.8 1.0 0.8 0.2 -1.0 0.2 0.4 -0.1 -0.3
Had other major operations 0.9 1.1 6.2 0.5 0.1 2.3 0.6 0.3 0.4 -0.1 1.0 0.1 -0.2 0.4 -0.1 -1.9 -2.5 0.0 1.3 0.1
Forced vital capacity (FVC) 0.2 0.6 1.8 0.9 0.8 0.9 0.9 0.8 1.0 0.5 0.2 -0.2 0.5 -1.0 1.2 0.3 -1.3 0.2 0.3 -1.0
Heel bone mineral density (BMD) T-score, automated (right) 0.6 1.3 5.4 -0.3 -1.3 2.3 -1.5 -0.8 -0.4 -1.2 -0.3 1.2 -0.9 0.5 -1.6 -1.3 -0.9 -0.5 1.6 0.4
Ever unenthusiastic/disinterested for a whole week 0.5 0.6 5.7 -2.4 -0.1 -0.2 0.2 -0.2 0.6 0.0 0.1 0.1 -0.7 -0.2 -0.5 -1.1 -0.9 0.9 0.4 0.5
Qualifications: None of the above 0.2 0.4 1.7 -0.2 0.8 -0.2 0.5 -0.5 1.3 0.7 -0.3 0.1 0.1 -0.1 0.8 0.3 -1.1 -0.5 0.3 0.9
Financial difficulties in last 2 years 1.2 1.6 6.0 -0.5 1.3 -0.5 -0.3 0.8 2.4 1.0 1.6 -0.4 0.2 -1.8 2.1 0.7 -2.4 0.4 0.6 -0.9
Mouth/teeth dental problems 0.7 1.0 3.1 1.3 0.3 0.3 1.2 0.4 -1.0 0.6 0.6 -1.7 1.0 1.4 -1.1 -0.2 -0.2 1.1 -1.8 0.7
Heart attack 0.3 0.4 2.7 -0.1 -0.1 -0.8 -1.6 -0.0 -0.1 0.1 0.6 0.1 -0.2 -0.1 0.8 0.6 0.9 -0.7 -0.2 0.2
Allergy 0.2 0.4 3.9 2.0 0.2 -0.4 1.2 0.2 0.5 0.2 -0.0 -0.2 0.2 -0.3 -0.1 0.4 -0.6 0.8 -0.3 -0.4
Pain all over the body in last month 0.9 0.9 4.1 -0.1 0.4 -0.1 1.0 0.0 -0.5 0.5 1.0 -1.1 0.9 1.0 0.8 -2.0 -0.9 0.1 0.8 1.9
Diabetes (self-reported) 0.9 1.3 4.1 -1.1 0.8 -0.3 -1.5 1.0 1.9 0.3 2.0 -0.3 -0.4 -1.6 1.1 -0.8 -1.4 -1.2 0.4 -1.1
Hayfever/allergic rhinitis (self-reported) 3.7 4.8 10.5 -2.8 -2.7 1.7 -0.5 -2.7 -3.2 -2.6 -2.3 2.7 -1.9 1.1 -2.8 -0.8 0.5 -2.4 2.6 0.6
Medication: Ramipril 1.0 1.2 2.8 -1.0 -1.2 0.3 -0.2 -1.2 -0.8 -1.2 -1.4 1.4 -1.2 0.3 -1.4 -1.7 1.3 -0.2 0.9 1.3
Medication: Simvastatin 0.4 0.6 2.0 -0.7 1.1 -0.8 0.3 1.0 1.0 0.8 1.4 -0.9 0.7 -0.6 0.4 -0.8 -0.6 -0.9 0.1 0.0
Fluid intelligence score 0.5 1.1 3.9 0.3 0.4 -2.0 -1.3 1.4 1.8 0.3 0.9 -0.7 0.2 -1.5 0.2 0.7 1.0 0.3 -0.5 -1.2
Illnesses of siblings 1.4 1.9 4.8 0.9 -2.2 0.2 -0.2 -1.5 -2.0 -1.8 -2.2 1.8 -1.9 0.1 -2.1 0.4 0.4 -0.9 0.3 0.4
Neuroticism score 2.3 4.8 12.9 2.5 2.8 -1.3 3.1 -0.4 -0.1 3.1 0.1 -1.8 3.6 2.2 2.1 1.2 2.4 1.7 -1.6 2.9
Weight 0.8 4.1 16.5 -3.4 -1.9 0.4 -4.1 -3.0 -0.6 -1.4 0.5 1.0 -2.3 1.0 -0.9 -2.1 1.8 -2.0 0.6 2.3
Impedance of arm (right) 0.2 1.1 8.6 -0.1 -0.3 -0.6 -0.2 0.4 -0.2 -0.5 -1.1 1.0 -0.3 -1.6 0.2 1.8 -0.3 -1.0 0.8 -2.9
Arm fat percentage (right) 1.8 7.3 24.6 -4.5 -3.2 0.5 -5.0 -2.8 -0.9 -3.0 -0.1 2.4 -3.7 -0.4 -1.9 -2.5 1.1 -3.5 2.5 0.7
Trunk fat-free mass 0.3 1.8 8.6 -0.4 -0.1 0.1 -1.6 -2.1 -0.6 0.5 1.3 -0.4 -0.1 1.8 0.4 -0.7 2.5 0.3 -1.3 2.9
Hip circumference 0.7 3.1 11.9 -3.0 -1.4 1.0 -3.5 -2.5 -0.4 -1.2 0.5 0.9 -1.7 0.9 -0.4 -2.5 1.1 -2.1 1.0 1.9
Time employed in main current job 1.8 2.1 6.5 -0.4 -1.7 0.9 -1.0 -0.1 -0.6 -1.9 -1.1 1.7 -2.0 -0.9 -1.5 -2.0 -1.7 -1.2 2.5 -0.3
Alcohol intake versus 10 years previously 1.8 2.7 6.5 1.2 2.4 -1.0 2.1 0.4 1.3 2.3 1.1 -2.5 2.2 0.9 1.6 1.5 -0.2 1.7 -1.7 1.4
Father’s age at death 0.3 0.4 1.3 1.2 0.5 1.1 0.4 0.0 0.3 0.7 0.9 -0.2 0.6 0.1 0.9 0.2 -0.9 0.1 0.4 0.4
Worrier / anxious feelings 1.9 3.6 12.3 1.8 1.9 -0.6 3.5 -0.4 -1.9 2.2 -0.4 -1.5 3.0 2.9 1.4 -0.6 1.3 1.6 -0.5 2.3
Frequency of tiredness / lethargy in last 2 weeks 2.7 4.3 12.5 1.1 3.0 -0.4 3.5 -0.1 1.6 3.2 1.3 -2.1 2.9 1.4 2.9 2.2 1.6 0.1 -1.0 2.2
Falls in the last year 1.4 1.9 4.8 -1.9 -1.3 1.6 0.8 -1.8 -0.8 -1.1 -1.3 1.9 -0.9 1.0 -1.7 -2.2 0.1 -1.0 1.4 1.2
Hair/balding pattern: Pattern 3 3.2 4.8 13.3 -2.9 -2.3 1.1 -0.8 -1.4 -1.5 -2.5 -1.6 3.0 -1.9 0.1 -3.7 -2.9 -1.2 -2.6 3.2 0.3
Number of live births 1.7 2.3 8.5 1.4 2.2 -0.8 0.6 1.4 2.9 2.1 1.9 -1.2 1.2 -0.8 2.6 -0.1 -1.2 1.3 0.4 -0.1
Forced expiratory volume in 1-second (FEV1) 0.2 0.6 3.8 0.7 0.4 1.2 0.5 0.8 0.5 0.1 0.4 -0.3 0.3 -1.0 0.9 0.2 -2.0 0.0 0.3 -1.0
Pulse rate 1.6 2.7 8.4 1.8 0.9 1.1 1.3 -1.0 -0.7 1.6 -0.4 -1.1 0.6 1.9 1.5 2.3 1.5 2.9 -2.2 2.7
Happiness 0.7 0.9 2.8 0.2 0.3 -1.5 0.9 -1.0 -1.2 0.6 -0.3 -0.2 0.8 1.1 -0.1 0.4 1.5 0.4 -1.7 1.4
Noisy workplace 0.7 0.8 3.6 -0.6 1.1 -1.9 0.3 -0.1 0.5 1.1 0.8 -0.9 1.0 0.5 1.5 0.5 0.8 -1.0 -0.1 0.6
Qualifications: A levels/AS levels or equivalent 0.1 0.3 1.0 0.3 -0.0 1.0 -0.1 0.7 -0.1 -0.0 0.7 0.1 -0.0 -0.4 0.3 0.7 0.8 -0.2 -0.6 -0.8
Serious illness, injury or assault of a close relative in last 2 years 0.6 0.7 2.8 -0.2 1.2 -0.8 1.3 0.8 1.7 0.9 1.3 -0.5 0.6 -0.5 1.1 -0.6 -0.3 0.2 0.2 -0.0
Mouth/teeth dental problems: Dentures 1.1 1.8 6.3 -2.0 -0.8 -0.6 -1.4 0.6 1.6 -1.2 -0.2 1.4 -1.4 -2.5 -0.7 -0.5 -0.1 -1.2 1.9 -1.8
Asthma 0.6 1.1 4.0 -0.0 1.0 -0.0 1.1 -0.7 -0.4 1.4 0.1 -0.6 1.2 1.8 1.0 0.1 0.0 2.0 -0.8 1.8
Medication: Ibuprofen (e.g. Nurofen) 0.9 1.2 5.7 0.5 1.6 0.4 2.4 0.0 0.3 1.6 1.0 -1.1 1.3 0.8 1.5 -0.8 -0.1 -0.4 0.7 0.8
Medication: Cholesterol lowering 0.2 0.2 0.8 -0.5 0.4 -0.7 0.6 -0.0 -0.1 0.4 0.6 -0.4 0.2 -0.2 0.2 0.5 0.7 -0.9 -0.0 0.8
Depression (self-reported) 0.3 0.4 1.1 -0.5 0.8 0.6 -0.1 0.8 1.1 0.3 0.6 -0.2 0.1 -0.9 0.8 0.1 -0.5 -0.1 0.5 -1.0
Medication: Lansoprazole 2.0 2.2 7.6 -0.6 1.3 -0.5 0.0 1.3 1.7 0.5 2.4 -0.2 0.9 -1.8 1.1 -1.7 -2.8 -1.9 2.2 -0.9
Prospective memory result 0.9 1.1 6.8 1.2 0.3 0.7 1.6 -0.8 -0.9 0.8 0.2 -1.2 0.2 1.2 1.1 0.4 -0.6 0.1 -1.0 2.6
Lung cancer (father) 0.3 0.4 1.3 -0.2 -0.4 0.1 -0.5 0.2 0.2 -0.7 1.0 0.2 -0.8 -0.9 -0.3 -0.5 -1.1 -0.6 0.7 -0.6
Illnesses of mother 0.3 0.3 1.4 0.6 0.4 -0.6 -0.8 0.1 1.2 0.4 0.0 0.0 -0.4 -0.7 0.6 1.0 -0.5 0.2 -0.5 -0.6
Forced expiratory volume in 1-second (FEV1), Best measure 0.2 0.7 2.5 1.3 0.9 0.7 0.8 0.7 0.9 0.7 0.6 -0.6 0.4 -0.6 1.6 0.4 -1.4 0.3 -0.1 -0.0
Pulse wave Arterial Stiffness index 2.5 2.9 7.6 0.5 2.5 0.4 0.8 1.8 1.2 2.2 2.7 -2.6 2.8 1.1 2.2 -0.2 -1.1 -0.3 -0.5 1.4
Impedance of arm (left) 0.2 0.7 7.1 0.1 0.2 -0.3 0.3 0.9 0.1 -0.0 -0.6 0.2 0.2 -1.2 0.3 1.2 -0.5 -0.4 0.2 -2.7
Arm fat mass (right) 1.3 5.4 20.8 -4.1 -2.5 0.5 -4.6 -2.8 -0.7 -2.3 0.4 1.6 -3.0 0.3 -1.4 -2.6 1.3 -2.7 1.7 1.7
Trunk predicted mass 0.3 1.9 9.6 -0.3 -0.2 0.1 -1.5 -2.3 -0.7 0.5 1.1 -0.3 -0.1 2.0 0.4 -0.5 2.6 0.4 -1.4 3.1
Standing height 0.2 1.5 4.0 0.6 1.2 -0.5 -0.3 -1.2 -0.2 1.8 0.7 -0.8 1.2 1.3 1.6 1.3 1.9 1.0 -2.0 1.3
Length of working week for main job 0.6 0.6 6.5 -0.1 0.4 0.7 0.0 -0.6 0.4 0.5 -0.5 -0.3 -0.0 -0.6 0.9 2.5 -0.6 -0.7 -0.7 -0.3
Exposure to tobacco smoke at home 0.4 0.4 2.4 -0.7 0.7 -1.5 0.3 -0.1 0.8 0.7 0.0 -0.4 0.5 0.0 0.6 0.8 -0.7 0.3 0.1 -0.5
Breastfed as a baby 1.5 1.8 9.5 -1.7 -1.2 -0.7 -2.3 0.0 -1.1 -1.5 0.6 1.0 -0.6 -0.5 -0.9 -1.4 0.4 -3.1 1.2 -1.2
Tense / ‘highly strung’ 4.0 6.6 19.4 2.1 1.1 -0.4 2.2 -2.9 -2.1 2.2 -1.7 -1.2 2.2 4.4 1.6 3.1 3.5 3.1 -2.6 3.7
Seen doctor (GP) for nerves, anxiety, tension or depression 0.7 1.1 4.8 -1.5 1.0 -1.1 2.2 -0.4 -0.5 0.9 0.6 -0.8 1.4 1.2 0.4 -0.6 -0.3 0.4 0.1 1.7
Hair/balding pattern: Pattern 4 0.7 1.7 5.4 -2.3 -1.4 -0.9 0.6 -1.8 -2.2 -1.1 -0.5 0.8 -1.0 1.1 -1.6 -1.2 -0.7 -0.7 -0.2 1.4
Birth weight of first child 0.3 0.5 2.2 -0.1 -0.3 -0.8 -1.5 0.7 0.2 -0.4 0.2 -0.2 -0.2 -1.0 -0.4 0.0 0.0 -0.9 -0.6 -1.4
Peak expiratory flow (PEF) 0.2 0.5 1.3 1.0 0.5 0.4 0.3 0.8 0.3 0.4 1.1 -0.7 0.6 -0.4 0.8 -0.1 -0.9 1.1 -0.9 -0.4
Pulse wave reflection index 1.7 2.1 6.0 -2.3 -0.8 1.1 -1.5 0.8 -0.0 -1.4 0.9 0.7 -0.6 -1.4 -0.6 -2.3 -1.7 -2.5 2.0 -1.1
Ever highly irritable/argumentative for 2 days 0.2 0.3 1.2 -0.8 0.2 -0.9 0.1 -0.5 -0.0 0.3 0.9 -0.1 0.1 0.1 0.2 -1.1 0.5 0.3 -0.1 0.6
Loud music exposure frequency 0.8 0.9 3.9 -0.6 0.6 -1.5 -0.0 1.6 0.9 0.3 0.8 -0.5 0.4 -2.0 0.2 0.0 -1.9 -0.0 0.3 -0.8
Qualifications: O levels/GCSEs or equivalent 0.3 0.4 1.8 -0.8 -0.5 1.3 -0.9 0.1 -0.7 -0.5 0.5 0.3 -0.1 -0.1 -0.3 -1.2 1.1 0.2 -0.1 -0.0
Mouth/teeth dental problems: Bleeding gums 0.2 0.3 1.1 -0.7 0.1 0.1 -0.3 -0.5 -0.1 0.2 -0.9 1.0 -0.0 0.2 0.9 1.0 0.3 -0.3 0.4 0.3
Blood clot in the leg (DVT) 0.5 0.7 2.2 0.4 1.0 -0.9 -1.4 0.6 1.5 0.8 0.5 -0.4 0.2 -0.6 1.4 0.3 -0.8 -0.7 -0.4 -0.0
Medication: Paracetamol 1.0 1.7 5.2 1.1 1.9 -1.2 2.3 1.1 1.3 1.6 1.3 -1.5 1.7 0.0 1.7 0.1 -0.3 -0.9 0.8 0.0
Headache pain in last month 0.7 1.2 4.0 -0.4 1.4 -1.5 2.0 -0.6 0.6 1.5 0.9 -0.7 1.3 1.3 0.8 -0.0 -0.4 1.0 0.2 1.4
Medication for cholesterol, blood pressure or diabetes 0.4 0.7 2.9 1.7 0.6 1.0 0.0 0.9 0.1 0.6 0.2 -0.5 1.1 0.7 0.4 0.0 -1.3 1.3 -0.4 -0.9
Glaucoma (self-reported) 0.9 1.0 3.6 -0.7 1.0 0.7 0.5 0.7 0.2 0.8 1.4 -1.9 1.3 0.3 1.4 -0.2 -0.2 1.9 -0.6 1.1
Gout (self-reported) 2.0 2.7 10.5 -0.7 -2.9 0.7 -1.2 -2.0 -3.2 -2.7 -0.3 1.6 -1.5 1.0 -2.8 0.3 0.4 0.1 0.7 0.5
Hypothyroidism/myxoedema (self-reported) 0.2 0.5 1.8 0.9 0.9 0.2 1.4 0.4 0.3 0.7 0.4 -1.3 0.5 0.4 0.7 0.5 -0.1 -0.3 -0.4 0.3
Medication: Amlodipine 0.3 0.4 1.9 -1.4 -0.4 0.1 0.0 -0.1 0.3 -0.6 -0.2 0.1 -0.5 -0.3 -0.7 -1.1 -0.2 -0.5 1.0 -0.3
Medication: Ventolin 100micrograms inhaler 0.4 0.5 2.2 0.3 0.1 -0.6 1.1 -1.1 -0.2 0.3 -1.1 0.5 0.2 0.9 0.6 0.5 0.1 0.9 -0.4 1.5
Birth weight 0.2 0.5 1.9 1.1 0.2 1.4 -1.0 -0.6 0.2 0.2 -1.0 0.1 -0.4 0.4 0.6 1.1 -0.6 -0.9 -0.3 0.4
Chronic bronchitis/emphysema (mother) 2.5 2.9 10.4 1.8 2.8 -0.6 -0.1 1.9 2.0 2.4 1.7 -1.8 2.3 -0.2 3.2 0.2 -1.6 0.8 -0.1 -0.1
High blood pressure (siblings) 0.9 1.2 2.9 -0.6 1.7 -0.5 1.2 0.9 1.4 1.6 1.2 -1.3 1.5 0.2 1.4 -0.2 0.5 1.6 -0.9 0.4
Forced vital capacity (FVC), Best measure 0.3 1.1 4.0 1.8 1.3 -0.0 0.9 0.8 1.3 1.2 0.5 -0.9 0.8 -0.7 2.0 1.1 -0.7 0.7 -0.7 -0.4
Body fat percentage 1.3 5.2 19.6 -4.4 -2.3 0.3 -4.4 -2.1 -0.4 -2.2 0.1 1.6 -2.9 -0.2 -1.6 -2.5 0.3 -3.1 2.2 0.8
Leg fat percentage (right) 1.3 4.7 14.0 -3.7 -2.1 1.0 -3.7 -2.0 -0.2 -2.3 -0.0 1.8 -2.8 -0.1 -1.6 -2.5 -0.4 -2.9 2.7 1.1
Arm fat-free mass (right) 0.4 1.8 10.9 -0.9 0.3 0.1 -1.6 -1.6 -0.2 0.9 1.4 -1.0 0.3 2.0 0.5 -1.2 1.5 0.6 -1.2 3.3
Exposure to tobacco smoke outside home 1.5 2.0 8.3 -1.0 -1.3 0.2 -0.8 -1.3 -1.2 -1.7 -1.7 1.9 -1.4 -0.1 -0.2 0.3 -1.9 -2.1 2.9 0.1
Comparative body size at age 10 3.9 10.8 24.5 -3.3 -4.6 2.3 -4.5 -2.3 -2.3 -4.9 -1.6 3.5 -4.5 -0.3 -4.1 -3.3 0.1 -4.3 2.6 -1.0
Number of full brothers 1.7 2.1 4.5 0.3 2.1 -0.8 1.7 1.2 2.0 1.8 1.7 -2.0 2.0 -0.6 1.8 1.2 -1.5 1.0 -0.3 -0.0
Worry too long after embarrassment 1.1 1.9 6.0 1.8 1.6 0.6 2.3 -0.0 -1.2 1.6 0.6 -0.9 2.4 2.0 0.1 -0.9 0.1 1.1 0.1 1.8
Seen a psychiatrist for nerves, anxiety, tension or depression 0.4 0.5 2.1 -1.4 -0.6 0.4 -0.6 -0.6 -0.4 -0.6 -0.2 1.5 -0.2 -0.1 -0.6 -0.2 0.4 -0.5 1.4 -0.1
Wheeze or whistling in the chest in last year 0.2 0.4 2.8 -0.8 -0.2 0.4 -0.3 -0.6 0.2 -0.3 -0.1 0.8 -0.3 0.1 0.1 -0.3 -0.9 -0.6 1.7 0.8
Number of children fathered 0.3 0.3 1.1 -0.3 0.8 -0.1 0.1 0.7 0.7 0.7 0.4 -0.7 0.8 -0.1 0.0 1.1 -0.4 -0.2 -0.7 -0.4
Reason for reducing amount of alcohol drunk: Health precaution 1.8 2.1 5.1 1.1 -1.4 0.5 1.9 -2.2 -2.3 -0.9 -2.2 1.6 -0.9 1.1 -0.8 2.2 1.7 0.2 -0.5 0.4
Age at first live birth 1.4 2.5 6.8 -2.0 -1.9 0.9 -1.7 -0.1 -1.1 -2.0 -1.0 1.9 -1.7 -0.4 -1.8 -2.6 0.9 -1.5 1.9 -1.1
Pulse wave peak to peak time 2.0 2.4 6.2 -0.6 -2.2 -0.6 -0.7 -1.7 -1.1 -1.9 -2.5 2.5 -2.5 -1.0 -2.1 0.2 1.1 0.3 0.3 -1.4
Health satisfaction 1.5 2.0 5.1 -1.1 2.2 -1.4 1.3 0.7 1.0 2.0 1.9 -1.7 2.2 0.8 1.9 -0.5 -0.0 1.0 -0.7 0.7
Shortness of breath walking on level ground 1.3 1.5 3.5 -1.7 -1.3 0.8 -1.5 -1.7 -1.5 -1.1 -1.2 1.4 -1.4 0.9 -0.6 -0.5 0.6 -0.6 0.9 1.9
Qualifications: College or University degree 0.3 0.9 5.8 1.7 -0.1 0.3 0.2 -0.0 0.3 0.3 0.2 0.6 -0.3 0.0 0.4 1.3 2.4 1.2 -1.4 -0.4
Eye problems/disorders: None of the above 0.7 0.8 2.5 1.2 1.1 -0.7 0.9 0.8 0.1 1.6 0.9 -0.9 1.3 0.6 0.7 -0.1 0.7 0.6 -1.3 -0.3
Mouth/teeth dental problems: Loose teeth 0.6 0.7 2.8 -1.1 -0.5 0.7 -1.6 -0.8 -0.2 -0.4 -0.1 0.9 -1.0 -0.2 0.8 1.7 0.1 -0.8 0.6 -0.3
Emphysema/chronic bronchitis 0.4 0.5 2.2 -0.4 0.5 -0.4 -1.3 1.0 0.8 0.3 0.3 -0.2 0.4 -0.0 0.5 -1.5 -0.4 -0.4 0.8 0.7
Medication for pain relief, constipation, heartburn 0.7 1.2 2.8 -0.1 -1.5 1.0 -1.7 -0.6 -1.1 -1.4 -1.6 1.7 -1.4 0.2 -1.2 0.6 -0.4 0.8 -0.2 -0.6
Neck or shoulder pain in last month 0.6 0.9 3.9 -0.6 0.4 1.2 1.1 -1.3 -0.9 0.3 -0.4 0.1 0.6 2.0 0.8 -0.5 0.6 -0.3 0.9 1.6
Medication: Blood pressure 1.4 2.6 5.2 -2.2 -2.0 0.5 -0.8 -2.1 -1.0 -1.9 -1.6 1.8 -2.3 -0.1 -1.7 -0.7 1.5 -2.2 1.0 1.6
Angina (self-reported) 0.4 0.5 2.0 -0.4 0.5 -1.4 -1.0 0.9 1.1 0.0 1.3 -0.3 0.3 -0.7 0.2 -0.5 0.0 -1.1 -0.1 0.2
Migraine (self-reported) 1.4 1.7 4.5 0.3 1.9 -0.9 2.1 1.7 0.3 1.8 1.3 -1.7 2.1 0.7 1.2 -0.4 -0.1 1.4 -0.7 0.3
Medication: Ibuprofen 1.6 1.9 5.1 0.4 2.3 -0.7 2.1 0.7 1.2 2.2 1.8 -1.6 1.8 0.6 2.1 -0.7 -0.4 -0.0 0.1 0.9
Medication: Allopurinol 0.8 1.1 3.5 0.1 -1.9 0.5 -0.4 -1.5 -1.7 -1.7 -0.0 1.0 -0.8 0.7 -1.8 0.9 -0.3 0.1 0.5 -0.4
Medication: Omeprazole 1.4 1.6 5.1 0.0 -1.7 -0.5 -0.7 -1.8 -0.1 -1.4 -1.1 1.9 -1.9 -0.6 -0.7 0.2 1.6 -2.3 1.2 0.2
Medication: Seretide 50 evohaler 0.7 0.8 7.2 -1.3 -0.6 -0.5 -0.7 0.4 0.7 -0.9 0.0 0.6 -0.6 -0.1 -0.7 -2.7 -0.4 -0.0 1.1 -0.2
Mean time to correctly identify matches 0.3 0.6 1.6 -1.0 0.4 -0.7 -0.7 0.6 1.3 0.1 0.7 -0.2 0.3 -0.7 0.6 1.1 -0.2 -1.1 0.7 -0.9
Heart disease (mother) 2.3 2.8 7.0 1.9 2.1 -0.3 2.5 1.0 0.2 2.2 2.5 -1.8 2.6 1.6 1.7 0.3 -0.3 1.5 -1.4 1.4
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.6 0.7 1.7 0.9 0.3 0.7 1.3 -0.0 -1.2 0.5 -0.4 -0.5 0.8 1.2 -0.4 0.6 1.3 0.4 -0.4 1.3
Whole body fat mass 1.1 4.8 19.5 -4.0 -2.1 0.4 -4.4 -2.7 -0.5 -1.9 0.4 1.3 -2.6 0.4 -1.3 -2.3 1.0 -2.7 1.5 1.7
Leg fat mass (right) 1.4 5.3 18.4 -3.9 -2.3 0.9 -4.3 -2.7 -0.6 -2.2 0.2 1.6 -2.9 0.4 -1.6 -2.6 0.5 -2.9 2.1 2.0
Arm predicted mass (right) 0.4 1.9 10.9 -1.1 0.0 0.1 -1.7 -2.0 -0.5 0.6 1.2 -0.7 0.0 2.1 0.2 -1.2 1.8 0.5 -1.2 3.3
Pulse rate, automated reading 0.4 1.2 3.5 1.4 1.1 -0.3 0.4 0.1 1.2 1.3 1.3 -1.6 0.9 0.6 1.4 0.3 0.3 1.9 -1.0 1.0
Alcohol intake frequency. 0.7 1.7 8.2 0.4 0.6 -0.8 2.9 -1.6 -0.1 0.8 -0.1 -0.5 0.9 2.3 0.3 -0.9 1.0 1.3 0.0 2.6
Comparative height size at age 10 0.3 1.8 6.4 -0.1 -1.0 -0.1 -1.3 -2.5 -2.2 -0.4 -0.5 0.5 -0.4 2.5 -0.1 -0.3 2.3 -0.0 -0.8 1.9
Number of full sisters 3.2 3.8 11.2 1.9 3.2 -1.2 2.2 1.8 3.1 2.7 1.5 -2.2 2.2 -0.3 3.4 1.0 0.2 0.8 -0.6 -0.1
Suffer from ‘nerves’ 2.2 3.5 9.7 1.3 1.9 0.1 1.7 -1.0 -1.4 2.5 0.2 -1.6 3.0 3.1 1.4 -0.4 2.3 1.7 -1.0 3.0
Overall health rating 1.3 2.7 6.1 -1.1 2.0 -1.3 1.3 -0.5 0.7 2.1 1.3 -2.0 2.3 2.2 2.5 -0.0 1.8 0.8 -1.1 2.3
Chest pain or discomfort 1.0 1.4 3.2 -1.6 1.4 -1.0 0.9 1.0 1.8 1.1 1.7 -0.8 1.0 -0.9 1.7 -0.9 -1.3 -0.8 0.6 0.2
Had major operations 1.5 1.7 5.0 -0.1 2.0 0.1 1.0 1.5 2.0 1.6 2.2 -1.1 1.8 -0.5 1.2 -1.4 -1.3 0.3 0.5 -0.7
Age at last live birth 0.3 0.4 2.2 0.2 -0.6 -0.3 -1.5 0.4 -0.7 -0.5 0.1 0.5 -0.6 0.0 0.2 -1.0 0.6 -0.6 0.4 -0.5
Family relationship satisfaction 0.2 0.3 1.1 0.3 0.4 -1.1 0.2 -0.4 0.1 0.1 0.5 0.0 0.7 -0.0 0.2 0.9 0.4 -1.0 -0.3 0.0
Leg pain on walking 0.9 1.2 2.8 -0.7 -1.2 1.5 -1.7 -1.4 -1.3 -0.8 -0.9 1.2 -0.9 1.3 -0.7 0.0 1.0 -0.6 0.2 1.5
Qualifications: NVQ or HND or HNC or equivalent 0.4 0.4 1.7 0.0 -0.1 0.1 1.1 -0.7 -1.0 -0.1 0.3 -0.8 0.2 0.6 0.3 1.3 0.6 1.0 -0.6 -0.1
Commuting to job workplace: Car/motor vehicle 0.3 0.4 1.4 0.7 0.1 -0.1 -0.5 -0.2 -0.6 0.4 0.8 -0.8 0.1 0.8 0.6 1.2 -1.0 0.1 -0.4 0.8
Illness, injury, bereavement, stress in last 2 years 0.8 1.0 3.1 -0.1 -1.6 0.2 -0.4 -0.4 -1.7 -1.5 -1.2 0.9 -1.1 -0.2 -1.8 -0.1 0.6 -1.2 0.3 -0.3
Medication: Aspirin 0.5 0.6 2.9 0.1 0.3 -0.6 -0.5 0.2 -0.4 0.4 1.1 -1.2 0.7 0.3 -0.3 -0.7 0.9 0.5 -1.7 1.2
Supplements: Vitamin C 0.7 0.8 1.9 -1.4 1.1 -1.0 0.9 1.0 0.2 0.8 1.2 -0.7 1.3 -0.7 1.4 0.5 -0.5 -0.3 -0.2 -1.0
Knee pain experienced in last month 0.6 0.9 2.9 -0.8 -0.6 1.7 -1.5 -1.5 -0.4 -0.6 0.0 1.6 -0.4 0.9 0.2 -0.3 0.8 -0.9 0.8 0.8
Hypertension (Self-reported) 0.6 1.6 7.7 -2.8 -0.8 0.4 -0.6 -0.6 0.5 -1.0 -0.0 0.7 -1.2 -0.3 -0.5 -2.0 0.3 -1.9 2.4 0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.6 0.8 4.1 -0.1 0.1 -0.8 -1.0 0.4 1.2 -0.3 0.6 0.6 -0.5 -2.0 1.0 0.2 -1.1 -0.7 0.6 -1.1
Illnesses of father: Heart disease 1.7 2.4 5.8 0.3 1.9 -2.0 -0.0 0.6 0.2 1.9 1.8 -2.0 1.9 1.4 2.4 -1.1 1.9 0.8 -1.5 1.2
Illnesses of siblings: Diabetes 0.9 1.2 2.6 -1.1 -1.1 0.6 -1.4 -1.6 -1.5 -1.0 -1.3 0.9 -0.6 1.6 -0.9 -0.0 1.3 -0.4 0.4 1.0
Smoking status: Previous 0.3 0.5 1.6 -0.0 1.0 -0.1 0.2 0.7 0.9 1.3 0.3 -0.8 1.0 0.3 0.9 -0.5 0.2 0.6 -1.0 -0.1
Forced expiratory volume in 1-second (FEV1), predicted 0.2 0.4 1.0 0.7 0.7 -0.2 -0.2 0.2 0.1 0.8 -0.0 -0.8 0.4 0.2 1.0 -0.7 0.4 0.9 -1.0 0.5
Whole body fat-free mass 0.4 2.1 9.5 -1.1 -0.4 -0.0 -2.0 -2.4 -0.7 0.2 1.1 -0.3 -0.4 1.9 0.2 -0.9 2.5 0.0 -1.3 3.1
Leg fat-free mass (right) 0.4 2.3 7.4 -1.9 -0.9 -0.2 -2.6 -2.7 -0.9 -0.3 0.9 -0.1 -0.9 1.6 -0.1 -1.1 2.5 -0.4 -1.0 2.7
Arm fat percentage (left) 1.7 6.8 23.5 -4.7 -3.0 0.5 -4.8 -2.6 -0.8 -2.8 0.1 2.0 -3.5 -0.3 -2.0 -2.7 1.0 -3.3 2.2 0.8
Average weekly red wine intake 0.1 0.2 1.0 -0.4 -0.1 0.5 0.4 0.3 -0.1 -0.1 -0.4 0.6 -0.3 -0.1 -0.2 -0.1 0.5 0.0 -0.2 -1.0
Handedness (chirality/laterality): Left-handed 0.7 0.8 2.7 0.7 -0.1 -1.2 0.3 0.9 1.6 -0.4 0.1 0.3 -0.7 -1.6 -0.0 -0.9 -0.3 -1.4 0.3 -1.5
Mood swings 1.6 3.0 7.8 2.0 2.3 -1.7 2.8 -0.1 0.4 2.4 0.5 -1.3 2.4 1.8 2.1 0.8 1.7 0.4 -1.2 2.0
Loneliness, isolation 1.6 2.2 5.3 1.8 2.1 -0.7 0.4 1.0 1.1 2.0 1.1 -1.8 2.1 0.5 2.3 1.8 0.9 1.2 -1.4 0.8
Long-standing illness, disability or infirmity 0.5 0.8 3.6 -1.9 0.4 0.5 1.3 -1.2 0.4 0.3 0.3 0.5 -0.1 0.8 0.8 -1.6 0.2 -0.1 1.1 1.2
Ever had bowel cancer screening 1.1 1.3 3.7 1.9 1.4 0.1 0.8 1.1 0.7 1.4 1.5 -1.8 1.9 0.9 1.1 0.1 0.1 1.0 -0.7 -0.1
Diabetes diagnosed by doctor 0.9 1.5 5.0 -1.6 1.0 0.3 -1.4 1.1 1.7 0.4 2.2 -0.7 0.4 -1.1 1.3 -1.5 -1.5 -1.0 1.0 -0.7
Ever had stillbirth, spontaneous miscarriage or termination 0.5 0.5 1.9 1.4 0.0 0.8 0.2 -1.0 -0.7 0.4 -0.5 0.4 0.2 1.2 0.3 0.3 -0.2 -0.7 -0.2 1.1
Friendships satisfaction 1.6 2.0 8.0 1.6 1.4 -0.6 2.3 -0.3 0.3 1.7 -0.5 -0.8 1.5 1.0 1.6 2.8 1.6 0.8 -1.6 0.6
Qualifications: nursing, teaching 0.6 0.9 2.9 -0.2 -0.8 0.4 -1.5 0.8 -0.9 -1.0 0.9 0.6 -0.5 -0.3 -0.4 -1.6 0.3 -1.7 0.6 -1.2
Commuting to job workplace: Walk 0.9 0.9 5.1 0.9 1.0 -0.4 2.2 0.2 -0.0 1.1 -0.3 -0.6 1.1 0.4 0.3 1.0 0.2 1.5 -1.3 -0.6
Eye problems/disorders: Cataract 0.2 0.2 0.5 -0.2 -0.4 0.5 0.5 -0.6 -0.6 -0.5 -0.4 0.4 -0.3 0.6 -0.6 0.3 -0.5 -0.0 0.7 0.4
Mouth/teeth dental problems: Mouth ulcers 0.4 0.6 2.5 -0.2 0.5 0.1 1.6 0.8 0.5 -0.1 -0.1 0.0 -0.1 -0.9 0.1 -1.0 -1.0 -1.2 0.8 -1.0
Medication for cholesterol 2.8 4.2 16.3 0.6 -2.2 0.5 -0.7 -4.0 -2.6 -1.3 -2.9 2.7 -2.3 2.0 -1.2 0.6 2.6 -0.3 -0.4 2.6
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.3 1.5 7.7 1.5 1.2 1.7 1.0 1.4 0.9 1.0 1.1 -1.0 1.5 -0.2 0.9 0.5 -2.8 1.0 -0.1 -0.4
Back pain experienced in last month 0.9 1.4 4.7 0.7 1.7 -1.3 2.2 -0.3 1.2 1.8 0.6 -0.6 1.3 0.5 1.9 0.7 -1.0 0.1 0.5 0.7
Mineral and other dietary supplements 0.9 1.2 5.9 0.2 1.2 -2.4 0.4 1.6 1.3 1.0 1.1 -1.5 0.7 -1.0 0.6 0.0 0.5 1.1 -1.2 0.3
Breast cancer (self-reported) 0.7 0.8 2.8 0.0 1.1 -1.7 1.0 1.0 1.3 1.0 0.6 -0.4 0.9 -0.7 0.6 -0.5 1.3 -0.3 -0.3 -0.3
Asthma (self-reported) 0.4 0.9 3.0 -0.1 0.9 0.2 1.0 -0.5 -0.5 1.2 0.1 -0.5 1.1 1.7 1.0 0.1 -0.0 1.7 -0.5 1.6
Osteoporosis (self-reported) 0.5 0.6 3.3 0.6 -0.4 0.2 -0.1 -0.6 -1.5 -0.6 -0.1 0.6 0.4 1.2 -0.3 0.6 0.8 -1.8 0.4 -0.1
Osteoarthritis (self-reported) 0.2 0.2 0.6 -0.1 -0.2 0.4 0.1 -0.5 -0.1 -0.4 -0.5 0.7 -0.4 0.1 0.0 -0.7 0.3 -0.6 0.8 0.6
Medication: Aspirin 0.5 0.6 3.1 -0.3 -0.1 -0.1 -0.6 -0.3 -0.9 0.1 0.6 -0.8 0.4 0.7 -0.4 -0.8 0.9 0.6 -1.6 1.8
Medication: Gliclazide 0.1 0.2 0.5 -0.5 -0.2 0.1 -0.6 -0.1 0.4 -0.5 -0.2 -0.1 -0.6 0.0 0.2 -0.4 -0.5 -0.6 0.7 0.0
Illnesses of father: None of the above (group 1) 1.1 1.4 3.7 -1.0 -1.1 0.8 -0.8 0.4 0.5 -1.5 -0.3 1.6 -1.3 -1.8 -1.3 0.1 -1.0 -0.9 1.9 -1.5
Smoking status: Current 0.2 0.2 0.9 -0.7 0.4 -0.1 0.5 0.1 -1.0 0.2 0.2 -0.5 0.9 0.6 -0.5 -0.2 0.2 -0.2 0.4 0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.3 0.6 3.8 1.1 -0.2 2.0 0.5 -0.0 -0.8 -0.0 -0.5 -0.7 0.2 0.9 0.3 -0.1 -1.2 -0.2 -0.6 0.8
Whole body water mass 0.4 2.0 8.9 -1.1 -0.4 -0.0 -2.1 -2.3 -0.6 0.3 1.2 -0.3 -0.4 1.8 0.3 -0.9 2.6 0.0 -1.2 3.0
Leg predicted mass (right) 0.4 2.3 7.7 -1.8 -0.9 -0.3 -2.5 -2.7 -0.9 -0.2 0.9 -0.1 -0.8 1.6 -0.1 -1.1 2.5 -0.4 -1.1 2.8
Arm fat mass (left) 1.3 5.4 20.0 -4.1 -2.5 0.3 -4.5 -2.8 -0.7 -2.2 0.3 1.6 -3.0 0.3 -1.4 -2.5 1.4 -2.9 1.5 1.6
Number of self-reported non-cancer illnesses 0.8 1.4 9.5 -3.1 -0.6 -0.5 -0.3 -0.4 -0.6 -1.0 1.1 -0.2 -0.3 -0.3 -1.4 -2.2 -0.9 -1.3 0.8 -0.3
Average weekly champagne plus white wine intake 0.3 0.4 1.6 0.7 0.6 0.3 0.4 -0.3 -0.1 0.7 -0.4 -0.4 0.6 0.8 1.0 0.4 1.3 0.7 -0.8 0.6
Miserableness 2.0 3.5 10.8 1.4 3.0 -1.3 3.0 1.7 1.4 2.6 1.8 -2.4 3.3 0.6 1.9 -0.0 1.0 1.0 -0.5 0.1
Guilty feelings 1.5 2.3 9.8 1.4 1.2 -0.5 1.2 -0.8 -0.1 1.7 -0.9 -0.4 1.6 1.7 1.5 1.8 3.1 1.0 -1.3 2.4
Wears glasses or contact lenses 1.9 2.2 6.6 1.6 2.4 1.0 1.1 1.1 1.2 2.5 1.4 -1.0 2.1 0.7 2.6 -0.0 -0.8 1.4 -0.2 0.3
Ever taken oral contraceptive pill 0.7 0.7 2.8 0.6 -0.0 1.6 1.0 -1.1 -1.0 0.2 -0.6 0.4 0.4 1.1 -0.5 -0.1 0.6 1.1 0.2 1.7
Hearing aid user 2.5 2.8 14.4 -3.8 -1.2 1.0 -1.7 -0.8 0.7 -1.7 -0.7 1.8 -1.9 -2.1 -1.0 -1.5 -0.6 -1.9 2.0 -1.0
Mother’s age at death 0.4 0.5 1.5 0.2 -1.2 0.8 -0.5 -0.2 -0.2 -1.0 -0.7 0.6 -1.1 -0.1 -0.7 -0.8 0.4 0.2 0.0 -1.2
Financial situation satisfaction 0.9 1.1 5.4 -1.8 -0.1 0.6 -0.3 0.1 0.7 -0.5 0.6 0.4 -0.7 -1.5 0.4 -0.2 -2.3 -1.4 0.9 -1.4
Tinnitus: Yes, now most or all of the time 0.4 0.5 1.6 -0.7 0.6 1.0 -0.1 0.2 -0.2 0.6 0.8 -0.2 0.7 0.5 0.6 -0.9 -0.9 -0.8 1.3 0.4
Commuting to job workplace: Public transport 0.5 0.6 4.9 -0.2 -0.4 2.2 0.5 -0.7 -0.9 -0.2 -1.5 0.3 -0.3 1.1 -0.3 0.2 0.4 -0.0 -0.3 0.5
Eye problems/disorders: Glaucoma 0.8 0.9 3.3 -0.3 1.0 0.2 1.1 0.3 0.3 0.8 0.9 -1.5 1.1 0.1 1.5 1.3 -0.3 1.8 -0.7 1.1
Medication: Blood pressure 0.7 1.3 4.8 -0.8 0.8 0.3 0.0 2.2 1.9 0.4 1.4 -1.5 0.7 -1.2 0.5 -0.8 -1.2 0.3 0.8 -1.9
Pain type(s) experienced in last month: Hip pain 0.6 0.7 2.6 -1.1 -0.4 -1.4 0.2 -1.6 -0.4 -0.4 -0.4 1.1 -0.1 0.8 -0.5 -0.9 1.4 -0.3 0.0 0.6
Supplements: Fish oil (including cod liver oil) 1.4 1.8 6.4 0.8 -1.5 2.5 0.1 -1.8 -1.7 -1.2 -1.8 1.7 -1.2 1.3 -0.7 0.4 0.2 -1.1 1.4 -0.0
High cholesterol (Self-reported) 0.3 0.5 4.2 -2.1 0.4 -0.3 -0.6 0.2 0.7 0.1 0.6 -0.1 -0.2 -1.0 0.1 -0.6 -0.6 -0.7 0.6 -0.1
Medication: Bendroflumethiazide 0.3 0.5 2.1 -1.4 -0.7 1.2 -1.0 -0.7 0.3 -0.6 -0.4 0.2 -1.2 -0.7 -0.1 -0.3 -0.2 -0.2 0.9 0.1
Medication: Paracetamol 1.0 1.6 5.0 0.9 1.9 -1.0 2.2 1.1 1.7 1.6 1.2 -1.4 1.7 0.2 1.7 -0.1 -0.2 -0.6 0.5 0.2
Medication: Lisinopril 0.5 0.7 2.0 -0.9 0.3 -1.1 -0.3 1.1 1.0 0.2 1.4 -0.5 0.1 -1.2 0.5 -0.3 0.1 -1.2 0.3 -1.2
Medication: Atorvastatin 0.4 0.5 1.9 -1.4 -0.3 -0.3 -1.2 -1.0 -0.0 -0.2 -0.9 0.1 -1.0 -0.0 0.5 0.7 -0.3 0.5 0.2 1.2
Illnesses of father: High blood pressure 0.9 1.1 3.8 -1.9 -0.7 1.5 0.3 -0.1 -0.5 -1.0 -1.0 0.2 -0.3 -0.1 -1.4 -2.0 -1.2 -0.5 1.1 -0.5
Alcohol drinker status: Never 0.5 0.6 2.7 -0.1 -0.8 0.1 1.1 -1.6 -0.1 -0.2 -0.9 1.0 -0.7 0.8 0.6 -0.1 1.1 0.2 0.2 1.4
Ever smoked 0.5 0.9 1.9 -0.6 1.0 -1.0 0.7 0.1 0.3 1.1 0.2 -1.1 1.4 1.0 0.7 -1.2 1.3 0.7 -0.8 1.2
Basal metabolic rate 0.4 2.4 9.3 -1.6 -0.6 0.0 -2.6 -2.6 -0.7 -0.0 1.1 -0.1 -0.7 1.8 0.1 -1.3 2.5 -0.4 -0.9 3.0
Leg fat percentage (left) 1.2 4.2 13.9 -3.7 -2.0 0.9 -3.5 -2.1 -0.4 -2.0 0.1 1.4 -2.5 0.2 -1.5 -2.4 -0.2 -2.7 2.5 1.3
Arm fat-free mass (left) 0.3 1.7 8.5 -0.8 -0.1 -0.1 -1.8 -2.1 -0.4 0.5 1.0 -0.3 -0.3 1.8 0.7 -0.8 2.1 -0.1 -1.0 2.9
Number of operations (self-reported) 1.3 2.0 5.2 0.4 1.9 -0.3 1.4 1.2 1.3 1.8 2.3 -1.7 1.6 0.4 1.2 -1.6 -2.2 1.4 -0.3 0.4
Average weekly beer plus cider intake 1.3 1.9 9.4 -1.0 -0.1 -0.4 -1.4 1.2 0.7 -0.8 0.6 0.7 0.1 -1.4 0.1 0.1 -2.5 -2.6 3.1 -1.0
Irritability 2.2 3.7 11.1 2.4 2.1 -0.3 3.3 -0.9 -0.6 2.7 0.1 -1.0 2.6 2.5 2.1 1.5 1.8 0.8 -0.8 2.9
Risk taking 0.5 0.8 3.4 -0.4 -0.3 -0.1 0.4 -1.0 -1.8 0.2 0.9 -0.1 0.5 1.8 -0.3 0.3 1.1 0.3 -1.0 1.3
Ever had prostate specific antigen (PSA) test 0.4 0.5 4.3 -0.1 0.1 2.1 0.4 0.3 -0.1 -0.1 0.2 0.2 0.6 0.8 -0.2 -1.0 -0.8 -0.5 0.5 0.2
Fractured/broken bones in last 5 years 0.4 0.6 2.7 -0.0 0.6 -0.6 1.7 0.7 -0.6 0.7 1.4 -0.0 1.2 0.2 -0.4 -0.4 -0.4 0.7 -0.5 -0.4
Age started oral contraceptive pill 1.1 1.3 4.0 -0.3 -1.8 -0.1 -1.1 -0.3 -0.1 -2.0 -0.6 1.9 -1.7 -0.5 -1.0 -1.0 -0.9 -1.2 1.3 -0.9
Diastolic blood pressure, automated reading 1.0 2.9 6.4 -1.3 -2.4 1.0 -1.5 -1.7 -1.3 -2.5 -1.5 1.8 -2.4 -0.6 -2.4 -1.4 -0.6 -2.2 1.7 0.4
Ever depressed for a whole week 1.2 1.5 6.3 -1.3 0.7 0.2 2.5 -0.2 -0.9 0.8 1.0 -0.7 1.1 1.5 -0.5 -2.1 -1.5 1.2 0.4 1.6
Unable to work because of sickness or disability 1.1 1.5 6.4 -0.1 0.4 -1.3 -0.1 0.9 1.5 -0.2 1.2 0.6 -0.2 -1.2 0.3 -1.3 -2.0 -2.5 2.1 -0.5
Commuting to job workplace: Cycle 0.9 1.1 5.1 1.0 0.1 0.6 0.9 -1.0 -0.7 0.5 -0.4 0.2 0.4 1.6 1.2 1.0 2.2 0.7 -1.8 1.3
Myopia 1.4 2.1 5.1 1.8 1.7 0.2 1.3 0.9 0.6 2.3 0.8 -1.9 2.0 0.6 1.6 1.5 0.4 1.8 -2.0 -0.5
Vascular/heart problems diagnosed by doctor 0.4 1.2 5.0 2.2 0.1 -0.2 0.9 -0.4 -1.1 0.5 -1.1 0.1 0.6 1.0 0.3 2.2 0.6 1.4 -1.8 0.5
Cholesterol lowering medication 1.1 1.5 4.1 -1.0 1.4 -0.5 -0.2 1.4 2.0 1.0 1.9 -1.4 0.8 -1.0 1.1 -1.5 -2.0 0.3 0.5 -0.8
Medication: Omeprazole (e.g. Zanprol) 1.0 1.2 3.3 -0.4 -1.0 -1.5 -1.5 -0.8 0.7 -0.9 -0.1 1.3 -1.3 -1.2 -0.4 -0.1 1.8 -1.8 1.0 -0.4
Pain experienced in last month 0.6 1.0 3.5 0.2 -0.9 0.7 -1.6 1.0 0.3 -0.8 -1.1 0.4 -1.3 -1.9 -0.6 0.7 0.4 0.1 -0.9 -1.6
Supplements: Calcium 1.7 1.8 4.4 -0.7 -1.9 1.8 -1.1 -0.9 -2.1 -1.7 -1.3 1.7 -0.8 0.7 -1.5 0.2 0.6 -1.9 1.3 -0.8
Basal cell carcinoma (self-reported) 0.4 0.5 2.3 -0.1 -0.4 -1.1 -0.1 0.1 0.1 -0.6 -0.2 0.4 -0.8 -1.1 -0.6 1.5 -0.2 -0.5 0.4 -1.1
Heart attack/myocardial infarction (self-reported) 0.3 0.4 2.7 -0.1 -0.1 -0.9 -1.6 0.0 -0.1 0.1 0.7 0.0 -0.2 -0.2 0.8 0.7 1.2 -0.6 -0.4 0.0
Deep venous thrombosis (DVT) (self-reported) 0.6 0.7 2.4 1.0 1.1 -0.9 -1.0 0.6 1.4 1.0 0.6 -0.6 0.4 -0.4 1.6 0.5 -0.7 -0.9 -0.4 -0.1
Heart disease (siblings) 0.7 0.8 2.3 -0.3 0.5 0.9 -0.8 0.9 1.5 0.2 1.1 0.2 0.0 -1.1 0.9 0.0 -1.5 -0.5 1.3 -1.2
Alcohol drinker status: Previous 0.9 1.0 7.7 0.6 0.8 0.1 2.8 -0.3 -0.4 0.8 0.2 -0.6 1.2 1.6 0.8 0.1 0.7 0.7 0.1 1.1
Pack years of smoking 2.1 3.1 15.2 -3.9 -1.7 0.4 -1.9 -1.2 -0.6 -2.1 -0.8 1.7 -2.2 -0.8 -1.3 -2.2 -0.2 -1.9 2.3 0.7
Impedance of whole body 0.3 1.3 7.7 0.4 1.0 -0.4 1.2 1.8 0.5 0.5 -0.5 -0.2 0.9 -1.5 0.7 1.2 -1.7 -0.3 0.6 -2.8
Leg fat mass (left) 1.2 4.8 16.6 -3.8 -2.2 0.9 -4.1 -2.8 -0.7 -2.0 0.3 1.3 -2.7 0.6 -1.5 -2.5 0.6 -2.6 1.9 2.1
Arm predicted mass (left) 0.3 1.7 8.7 -1.1 -0.2 0.1 -1.7 -2.2 -0.5 0.3 1.0 -0.3 -0.3 1.8 0.5 -1.0 2.1 0.1 -0.8 3.0