Hub : Genes

GALNT2

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1090	0.0390	2.2e-03	0.027	0.028	0.060	0.044	0.063	2.9e-04	2.3e-04	8.2e-08	4.6e-06	3.5e-08
2	GTEx	Brain Cerebellum	0.4170	0.1040	8.5e-04	0.084	NA	0.009	NA	0.027	1.8e-03	NA	1.7e-01	NA	5.6e-02
3	GTEx	Esophagus Mucosa	0.2730	0.0590	8.2e-06	0.239	NA	0.196	NA	0.228	4.7e-16	NA	3.9e-13	NA	2.6e-15
4	METSIM	Adipose	0.0978	0.0314	1.4e-04	0.063	0.036	0.044	0.050	0.059	9.4e-10	3.4e-06	3.0e-07	5.8e-08	3.5e-09

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4
Bipolar Disorder (2018)	0.7	1.1	2.3	-1.5	-0.7	-1.2	0.4
Bipolar Disorder or Schizophrenia	0.7	1.7	3.1	0.1	1.6	-1.2	1.8
Depressed Affect (Nagel 2018)	2.2	4.6	10.2	-0.6	3.2	-0.8	-2.7
Depression (Nagel 2018)	3.8	5.6	16.1	-0.3	4.0	-2.5	0.2
Intelligence (Savage-Jansen 2018)	0.2	0.5	1.6	-0.1	-0.5	-1.3	-0.2
Neuroticism (Nagel 2018)	1.9	4.5	15.4	-0.4	3.9	-1.4	-0.7
Schizophrenia (2018)	1.6	3.3	7.1	1.4	2.7	-0.6	2.0
Schizophrenia vs Biploar Disorder	3.3	4.3	8.8	2.8	3.0	1.0	0.0
Worry (Nagel 2018)	2.0	4.2	11.9	0.4	3.5	-1.0	1.9
Alzheimer’s Disease (in mother)	0.6	0.7	1.8	0.8	0.1	0.6	1.4
Alzheimer’s Disease (in father)	0.4	0.5	0.9	-0.9	-1.0	-0.2	-0.1
Alzheimer’s Disease (including proxy)	0.2	0.2	0.8	0.1	-0.0	0.4	0.9
Crohns Disease (2017)	1.7	3.7	13.9	-0.7	-3.7	0.5	0.6
Irritable Bowel Disease (IBD)	1.5	3.5	13.5	0.0	-3.7	0.5	0.7
Ulcerative Colitis (UC)	0.6	1.1	3.3	0.9	-1.8	0.6	0.4
Major Depression (MDD)	0.9	1.1	1.4	-0.9	1.2	-0.9	-1.1
Reaction Time	0.5	0.9	2.8	-0.6	0.2	-1.7	0.7
Verbal and Numeric Reasoning (VNR)	0.1	0.2	0.4	-0.6	-0.7	0.0	0.0
Breast Cancer	0.3	0.6	1.9	0.4	-0.1	0.6	-1.4
Ovarian Cancer	0.3	0.3	0.7	-0.5	-0.3	-0.9	0.5
Prostate Cancer	0.3	0.4	0.9	1.0	0.2	0.5	-0.7
Age at First Birth	0.6	0.9	2.7	-0.3	1.6	0.6	0.6
Bipolar Disorder (2011)	1.4	1.4	5.3	0.0	-0.5	0.1	2.3
Body Mass Index (BMI) (2010)	0.8	1.1	3.9	2.0	-0.3	0.6	-0.4
Coronary Artery Disease (CAD)	1.6	1.9	3.8	-0.1	-1.8	0.7	-2.0
Crohns Disease (2012)	1.4	2.2	5.2	-0.4	-2.3	-0.3	1.9
Mean Putamen Volume	1.9	2.1	8.1	0.4	0.4	0.1	2.9
Fasting Glucose	1.2	1.4	3.4	1.9	0.4	1.3	-0.5
HbA1C	1.3	1.4	3.3	1.5	-0.0	-0.6	1.8
HDL Cholesterol	14.7	24.5	87.6	1.4	-2.1	-2.0	9.4
LDL Cholesterol	0.5	0.8	2.5	0.1	-1.6	-0.7	-0.5
Lupus	0.1	0.2	0.4	-0.5	0.6	-0.5	-0.0
Neuroticism (2016)	2.4	3.5	6.5	1.2	2.2	1.1	-2.5
Primary Biliary Cirrhosis	2.0	2.8	5.7	2.4	1.1	-2.0	0.7
Rheumatoid Arthritis	0.2	0.3	0.7	0.3	0.6	-0.8	0.3
Schizophrenia (2014)	1.3	2.8	7.5	0.5	2.7	-1.0	1.6
Triglycerides	10.3	16.9	55.8	-1.0	2.8	1.7	-7.5
Type 2 Diabetes (T2D) (2012)	0.4	0.5	0.8	0.9	-0.9	0.1	-0.6
Ulcerative Colitis	0.4	0.6	1.0	1.0	-0.9	0.5	0.6
Blood Eosinophil Count	0.5	3.7	12.1	0.5	-3.5	-0.8	1.3
Blood Platelet Count	4.4	50.9	171.6	0.2	-4.8	-2.9	13.1
Blood Red Count	0.6	5.5	15.4	-2.6	0.2	0.3	-3.9
Blood White Count	0.6	4.1	8.4	-0.8	2.9	1.6	-2.2
Heel T-Score	0.2	1.5	3.4	-1.2	0.4	-1.0	1.8
BMI	1.5	8.9	28.7	-1.9	1.8	0.3	-5.4
Height	0.4	7.6	24.5	-2.1	-0.1	1.2	5.0
Waist Hip Ratio (WHR)	0.5	2.4	6.9	0.1	-1.7	-2.6	0.3
Systolic Blood Pressure	0.4	1.9	4.1	0.0	-1.8	-0.4	2.0
Smoking Status	1.6	3.9	14.4	-0.4	-0.6	-3.8	-0.7
Allergy or Eczema	0.0	0.0	0.1	-0.3	0.0	-0.0	-0.2
Cardiovascular Disease	0.2	0.8	3.0	-0.1	0.3	0.5	-1.7
Hypothyroidism (self reported)	0.6	1.4	2.2	-1.0	-1.5	1.1	-1.1
Respiratory disease	0.2	0.4	1.0	-1.0	-0.5	0.2	-0.5
Type 2 Diabetes (T2D) (2018)	0.2	0.4	1.3	0.4	-0.5	0.2	-1.1
Lung FEV1/FVC ratio	0.1	0.7	1.7	0.4	0.7	-1.3	-0.6
Lung FVC	0.3	1.3	2.6	-1.1	0.5	-1.2	1.6
Neuroticism	2.6	6.2	18.7	1.0	4.3	-1.3	-1.8
Chronotype (morning person)	0.2	0.4	0.5	0.7	-0.7	0.1	-0.7
Hair Pigment	0.0	0.7	2.5	-1.6	0.1	0.3	-0.1
Tanning	0.1	1.3	2.0	1.3	-0.3	-1.4	-1.3
Hand grip strength (left)	0.2	0.5	1.6	-1.2	0.1	-0.2	0.7
Number of treatments/medications taken	0.8	1.5	4.6	-0.5	1.0	0.5	-2.1
Average weekly spirits intake	1.0	1.2	1.8	-1.0	-1.4	-1.3	-0.6
Sensitivity / hurt feelings	1.7	2.8	8.8	0.3	3.0	-0.6	-1.4
Frequency of depressed mood in last 2 weeks	3.8	5.3	14.1	-0.2	3.8	-2.5	-1.1
Hearing difficulty/problems: Yes	1.1	1.7	2.9	-1.2	1.7	-1.0	-1.2
Relative age of first facial hair	1.3	2.6	7.4	0.7	-0.0	2.7	-1.6
Other serious medical condition/disability diagnosed by doctor	1.2	1.6	3.3	-1.8	1.6	0.4	-0.6
Ever used hormone-replacement therapy (HRT)	1.3	1.7	2.8	1.3	0.9	-1.7	-1.2
Ever had hysterectomy (womb removed)	0.4	0.4	0.5	0.7	0.5	-0.7	-0.7
Systolic blood pressure, automated reading	1.0	3.0	6.1	-2.4	-2.5	0.4	-0.2
Eye problems/disorders: Diabetes related eye disease	3.0	3.3	10.4	-0.0	-0.3	1.6	-3.2
Angina	0.9	1.2	1.8	-0.2	1.1	1.3	-1.4
Medication for hormone replacement therapy	0.4	0.5	0.6	0.6	-0.7	-0.8	-0.7
Vitamin and mineral supplements	1.0	1.3	4.3	-0.3	-2.1	0.3	-0.9
Supplements: Zinc	1.0	1.1	3.3	1.0	-0.0	-0.3	1.8
Medication: Co-codamol	1.3	1.5	3.0	-0.6	1.7	-0.2	-1.6
Medication: Metformin	0.3	0.4	0.7	0.5	0.8	0.2	-0.8
Diabetes (father)	1.1	1.3	3.9	0.3	-2.0	-0.8	0.8
Diabetes (mother)	0.2	0.3	1.0	-1.0	0.2	0.1	0.1
Severe depression (siblings)	1.7	1.9	3.6	-1.9	0.4	-0.4	-1.9
Pack years adult smoking proportion	1.3	1.9	4.7	-1.1	0.6	1.2	-2.2
Impedance of leg (right)	0.8	3.8	11.9	0.4	-1.7	3.5	0.6
Leg fat-free mass (left)	0.3	1.5	2.9	-1.7	1.0	-1.5	-0.3
Trunk fat percentage	2.3	9.2	22.7	-1.9	0.7	3.2	-4.8
Hand grip strength (right)	0.4	1.1	1.9	-1.4	1.4	0.7	-0.1
Townsend deprivation index at recruitment	3.0	4.2	8.5	2.0	1.6	-1.2	-2.9
Current tobacco smoking	1.3	2.1	4.0	-1.0	-1.8	-2.0	-0.4
Average weekly fortified wine intake	0.4	0.4	0.8	-0.7	0.5	-0.3	0.9
Maternal smoking around birth	0.6	0.8	2.8	0.1	-0.5	-1.7	0.4
Fed-up feelings	3.4	6.1	12.6	-0.1	3.5	-1.1	-3.2
Frequency of unenthusiasm / disinterest in last 2 weeks	3.8	5.1	10.6	0.0	3.1	-3.2	-0.5
Relative age voice broke	0.4	0.6	2.1	-0.3	-0.1	0.6	-1.4
Taking other prescription medications	0.7	1.1	2.3	-1.2	-0.0	0.7	-1.5
Age when periods started (menarche)	1.0	2.3	6.9	-0.4	1.4	2.6	-0.3
Bilateral oophorectomy (both ovaries removed)	1.0	1.2	1.9	1.0	1.3	0.5	-1.4
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.5	1.3	0.2	1.1	0.6	0.6
Tinnitus: Yes, but not now, but have in the past	0.9	1.0	1.6	-1.0	0.2	-1.2	-1.1
Qualifications: CSEs or equivalent	2.7	3.6	9.1	-1.4	1.0	1.5	-3.0
Serious illness, injury or assault to yourself	2.4	3.0	10.5	0.2	1.1	-0.4	-3.2
High blood pressure	0.2	0.5	0.9	-0.7	-0.8	0.9	0.1
Hayfever, allergic rhinitis or eczema	0.0	0.0	0.1	-0.1	-0.2	-0.0	0.3
Multivitamins +/- minerals	0.3	0.3	0.7	-0.2	0.8	-0.4	0.7
Stomach or abdominal pain in last month	1.6	2.0	2.6	-1.0	-1.6	-1.3	1.6
Supplements: Glucosamine	0.5	0.6	1.8	1.4	0.5	0.4	-0.5
Diverticular disease/diverticulitis (self-reported)	1.0	1.2	3.4	-0.2	0.2	1.2	-1.8
Medication: Atenolol	2.2	2.8	5.6	1.6	2.4	0.6	-1.6
Medication: Levothyroxine sodium	0.3	0.5	1.8	-0.3	-0.2	0.1	-1.4
Sitting height	0.5	3.4	10.1	-0.9	-1.5	0.5	3.2
Chronic bronchitis/emphysema (father)	0.8	0.9	1.1	1.1	-0.8	1.0	-0.9
High blood pressure (mother)	0.7	1.1	1.7	-0.9	-1.1	-0.7	1.3
Body mass index (BMI)	1.4	6.0	20.2	-1.7	0.8	0.4	-4.5
Impedance of leg (left)	0.8	4.0	12.3	0.4	-1.9	3.5	0.3
Leg predicted mass (left)	0.3	1.5	3.0	-1.7	0.9	-1.5	-0.4
Trunk fat mass	1.4	6.2	14.4	-2.3	0.8	2.1	-3.8
Waist circumference	1.0	3.5	12.0	-1.5	-0.0	-0.0	-3.5
Number of incorrect matches in round	0.7	1.2	2.3	-1.1	1.1	-0.3	1.5
Past tobacco smoking	1.0	1.8	6.7	-0.3	-0.8	2.6	0.1
Alcohol usually taken with meals	0.9	1.4	3.7	1.9	-0.3	1.1	0.8
Nervous feelings	1.5	2.8	9.1	1.1	3.0	-0.5	0.8
Frequency of tenseness / restlessness in last 2 weeks	3.0	4.7	11.7	-0.6	3.4	-2.6	-0.3
Hearing difficulty/problems with background noise	1.2	1.9	5.0	-2.2	0.9	-0.4	-1.2
Hair/balding pattern: Pattern 2	0.5	0.7	2.2	-1.5	-0.8	-0.0	0.1
Had menopause	0.4	0.5	1.3	1.1	0.3	0.5	-0.6
Had other major operations	0.3	0.3	0.8	0.9	0.5	-0.1	-0.5
Forced vital capacity (FVC)	0.2	0.7	2.0	-1.4	-0.2	0.1	0.8
Heel bone mineral density (BMD) T-score, automated (right)	0.4	1.0	1.9	-0.8	1.4	1.2	0.3
Ever unenthusiastic/disinterested for a whole week	1.4	1.7	2.7	0.6	1.6	-1.6	-1.1
Qualifications: None of the above	0.7	1.6	3.7	0.6	1.9	1.5	-0.4
Financial difficulties in last 2 years	3.1	4.1	6.7	-0.2	2.6	-2.5	-2.0
Mouth/teeth dental problems	1.8	2.8	7.2	-2.7	-1.9	0.4	-0.2
Heart attack	1.2	1.6	5.2	0.3	1.0	0.2	-2.3
Allergy	0.2	0.4	1.3	-0.4	0.1	-0.1	1.2
Pain all over the body in last month	0.8	0.8	2.0	1.4	0.7	-0.4	-0.7
Diabetes (self-reported)	0.2	0.4	0.6	0.8	-0.7	-0.0	-0.7
Hayfever/allergic rhinitis (self-reported)	0.2	0.3	0.9	-0.2	-0.1	-1.0	0.4
Medication: Ramipril	0.5	0.7	0.9	0.9	-0.8	-0.7	-0.9
Medication: Simvastatin	0.4	0.6	1.3	-0.9	0.1	-1.1	-0.6
Fluid intelligence score	0.0	0.1	0.2	0.0	0.3	-0.0	0.5
Illnesses of siblings	1.1	1.5	4.8	-0.9	-0.0	-0.7	2.2
Neuroticism score	3.5	7.4	22.8	0.7	4.8	-1.6	-2.0
Weight	0.6	2.9	6.2	-2.2	0.2	0.4	-2.5
Impedance of arm (right)	0.3	1.6	6.1	0.2	-0.2	2.5	0.3
Arm fat percentage (right)	1.9	7.3	22.4	-1.5	1.2	1.7	-4.7
Trunk fat-free mass	0.3	1.8	3.0	-1.7	0.1	-1.5	1.3
Hip circumference	1.0	4.5	12.3	-1.4	-0.1	1.9	-3.5
Time employed in main current job	0.2	0.2	0.5	-0.0	0.2	0.7	0.5
Alcohol intake versus 10 years previously	0.3	0.5	0.6	0.7	0.7	0.6	0.8
Father’s age at death	0.5	0.7	1.4	-0.9	-1.2	0.1	0.6
Worrier / anxious feelings	2.2	4.1	16.0	0.7	4.0	-0.2	0.3
Frequency of tiredness / lethargy in last 2 weeks	2.8	4.5	12.5	-1.1	3.5	-1.4	-1.5
Falls in the last year	0.4	0.6	1.6	0.3	1.3	-0.8	-0.3
Hair/balding pattern: Pattern 3	2.4	3.5	8.1	2.9	-1.8	-1.1	1.3
Number of live births	0.1	0.1	0.3	0.3	0.6	-0.1	-0.3
Forced expiratory volume in 1-second (FEV1)	0.1	0.4	1.6	-1.3	-0.1	-0.2	0.4
Pulse rate	0.6	1.0	2.5	-0.4	-1.1	-0.4	-1.6
Happiness	0.4	0.5	1.1	0.7	0.5	-1.1	-0.2
Noisy workplace	0.4	0.5	1.7	-0.4	-1.3	-0.0	0.1
Qualifications: A levels/AS levels or equivalent	1.2	2.7	6.8	0.3	0.2	-2.6	2.0
Serious illness, injury or assault of a close relative in last 2 years	1.6	1.9	2.5	1.5	1.3	-1.6	-1.0
Mouth/teeth dental problems: Dentures	1.5	2.5	8.0	2.8	-1.3	0.4	0.5
Asthma	0.1	0.1	0.2	-0.5	-0.4	0.4	-0.2
Medication: Ibuprofen (e.g. Nurofen)	0.7	0.9	2.6	-1.6	0.7	0.3	-0.6
Medication: Cholesterol lowering	0.3	0.4	0.9	-0.2	1.0	-0.3	-0.9
Depression (self-reported)	0.6	0.7	2.6	-0.3	1.6	0.3	-0.0
Medication: Lansoprazole	0.8	1.0	1.8	-0.7	0.5	1.1	-1.4
Prospective memory result	2.1	2.6	6.2	1.6	2.5	0.1	-1.2
Lung cancer (father)	0.9	1.0	2.2	0.9	1.5	1.0	-0.0
Illnesses of mother	0.8	1.0	2.3	1.5	1.0	-0.8	0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.6	2.1	-1.4	0.2	0.2	0.3
Pulse wave Arterial Stiffness index	1.5	1.8	2.8	-1.6	-1.7	-0.5	1.2
Impedance of arm (left)	0.6	2.9	11.1	-0.0	-0.6	3.3	-0.0
Arm fat mass (right)	1.5	6.0	17.9	-1.7	1.0	1.4	-4.2
Trunk predicted mass	0.3	1.6	2.7	-1.6	0.2	-1.4	1.3
Standing height	0.4	4.4	13.8	-1.6	-1.0	0.7	3.7
Length of working week for main job	0.7	0.8	1.5	-0.4	-0.7	-1.0	1.2
Exposure to tobacco smoke at home	1.6	1.8	4.8	0.6	1.3	-2.2	0.7
Breastfed as a baby	0.4	0.5	0.9	0.6	-0.4	-0.9	0.6
Tense / ‘highly strung’	2.1	3.5	8.4	2.0	2.9	-1.2	-0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	2.4	3.7	9.4	0.3	2.2	-3.1	0.6
Hair/balding pattern: Pattern 4	0.2	0.4	0.6	-0.8	0.3	0.7	-0.6
Birth weight of first child	1.0	1.8	5.5	0.4	-0.7	-1.0	2.3
Peak expiratory flow (PEF)	0.2	0.4	1.2	0.2	0.2	-1.1	-0.6
Pulse wave reflection index	1.2	1.5	4.1	-1.2	0.0	-0.7	2.0
Ever highly irritable/argumentative for 2 days	1.0	1.2	3.1	0.0	-1.3	-1.8	-0.4
Loud music exposure frequency	0.1	0.1	0.2	-0.5	-0.4	0.1	-0.1
Qualifications: O levels/GCSEs or equivalent	1.9	3.1	7.2	-2.7	-0.9	-1.7	1.1
Mouth/teeth dental problems: Bleeding gums	0.2	0.2	0.5	0.0	0.6	-0.7	-0.2
Blood clot in the leg (DVT)	2.8	3.6	8.3	2.1	1.3	0.5	-2.9
Medication: Paracetamol	2.0	3.3	8.4	-2.9	2.0	-0.4	-0.9
Headache pain in last month	1.3	2.3	8.1	-2.9	0.8	-0.4	-0.5
Medication for cholesterol, blood pressure or diabetes	0.3	0.6	1.7	-1.3	-0.6	0.5	-0.1
Glaucoma (self-reported)	1.6	1.9	2.5	-1.6	1.6	1.1	-1.2
Gout (self-reported)	1.7	2.4	6.2	1.8	2.5	0.1	0.4
Hypothyroidism/myxoedema (self-reported)	0.4	0.7	1.3	-0.9	-0.8	0.1	-1.2
Medication: Amlodipine	0.7	1.0	3.2	0.6	-0.5	-0.4	1.8
Medication: Ventolin 100micrograms inhaler	0.7	0.9	1.6	-1.1	-1.3	-0.4	0.8
Birth weight	0.4	1.0	3.1	-0.1	0.9	-1.8	-0.0
Chronic bronchitis/emphysema (mother)	1.2	1.4	2.5	-0.8	-1.5	-1.6	0.5
High blood pressure (siblings)	0.7	1.0	1.8	1.4	-0.5	0.7	-1.2
Forced vital capacity (FVC), Best measure	0.4	1.3	4.2	-2.0	0.2	0.3	0.9
Body fat percentage	2.3	9.3	24.7	-1.7	0.7	3.0	-5.0
Leg fat percentage (right)	1.7	6.3	20.8	-0.9	0.5	1.8	-4.6
Arm fat-free mass (right)	0.2	0.9	3.3	-1.8	0.1	-0.7	-0.1
Exposure to tobacco smoke outside home	1.5	2.0	6.1	-0.6	1.2	-2.5	-0.1
Comparative body size at age 10	0.1	0.4	1.2	-1.1	-0.1	0.5	0.4
Number of full brothers	2.2	2.7	5.2	2.3	0.6	1.5	-1.8
Worry too long after embarrassment	0.8	1.3	4.7	-0.0	2.2	-0.6	-0.0
Seen a psychiatrist for nerves, anxiety, tension or depression	1.7	2.1	5.0	1.6	2.2	-0.9	0.4
Wheeze or whistling in the chest in last year	0.3	0.5	1.6	-0.4	-0.3	0.0	-1.3
Number of children fathered	1.5	1.7	5.6	-0.7	0.4	0.7	-2.4
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.4	0.9	0.9	0.5	0.5	-0.0
Age at first live birth	1.3	2.3	7.2	0.3	-0.7	1.3	2.7
Pulse wave peak to peak time	1.4	1.6	2.7	1.6	1.6	0.6	-1.0
Health satisfaction	0.8	1.0	2.0	1.4	-0.7	-0.8	-1.0
Shortness of breath walking on level ground	1.7	2.0	7.8	0.1	-0.2	-2.8	0.3
Qualifications: College or University degree	0.7	2.3	6.9	0.9	0.0	1.1	2.6
Eye problems/disorders: None of the above	0.2	0.2	0.5	-0.7	-0.1	0.6	0.2
Mouth/teeth dental problems: Loose teeth	0.3	0.4	0.9	-0.9	0.2	0.1	-0.7
Emphysema/chronic bronchitis	0.4	0.4	1.0	-0.6	-0.5	0.5	-1.0
Medication for pain relief, constipation, heartburn	1.4	2.4	3.7	1.9	-1.8	-0.5	1.6
Neck or shoulder pain in last month	0.7	1.0	2.0	-1.4	1.4	-0.2	-0.3
Medication: Blood pressure	0.4	0.7	1.2	1.0	0.7	-0.5	1.1
Angina (self-reported)	1.1	1.4	2.2	-0.2	1.1	1.5	-1.5
Migraine (self-reported)	0.5	0.6	0.9	0.6	0.8	-0.7	-0.9
Medication: Ibuprofen	0.9	1.1	3.7	-1.9	0.3	-0.3	-0.6
Medication: Allopurinol	0.3	0.5	1.3	1.1	0.5	0.3	0.6
Medication: Omeprazole	1.4	1.7	3.0	-0.6	1.7	0.8	-1.7
Medication: Seretide 50 evohaler	1.2	1.4	3.4	-1.0	0.6	0.9	-1.8
Mean time to correctly identify matches	0.2	0.4	0.8	-0.2	0.4	-0.9	0.8
Heart disease (mother)	4.8	5.9	13.0	-1.5	-0.9	2.7	-3.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.8	2.0	0.7	-0.9	0.1	1.4
Whole body fat mass	1.5	6.3	16.3	-1.9	0.8	2.1	-4.0
Leg fat mass (right)	1.1	4.4	13.5	-1.4	0.7	1.4	-3.7
Arm predicted mass (right)	0.1	0.6	2.1	-1.5	0.1	-0.6	0.2
Pulse rate, automated reading	0.4	1.2	1.9	1.2	-1.0	1.4	-0.6
Alcohol intake frequency.	0.2	0.6	1.8	-0.2	-1.3	0.6	-0.3
Comparative height size at age 10	0.6	3.2	8.0	-1.1	-1.9	0.3	2.8
Number of full sisters	1.1	1.3	2.7	0.0	0.6	1.6	-1.5
Suffer from ‘nerves’	1.0	1.6	3.8	1.4	1.9	-0.8	0.6
Overall health rating	0.4	0.8	2.9	-0.3	0.3	-0.4	-1.7
Chest pain or discomfort	0.7	1.0	1.9	-0.4	1.4	-0.6	-1.3
Had major operations	0.6	0.7	2.2	1.5	0.4	0.4	-0.5
Age at last live birth	2.3	3.4	7.3	1.0	-2.1	1.0	2.7
Family relationship satisfaction	0.9	1.2	3.2	0.4	1.8	-1.1	-0.2
Leg pain on walking	0.8	1.0	1.8	0.4	1.2	-0.8	-1.3
Qualifications: NVQ or HND or HNC or equivalent	2.7	3.2	10.9	0.6	-0.1	1.3	-3.3
Commuting to job workplace: Car/motor vehicle	0.8	0.9	2.8	-0.8	-0.1	-1.7	-0.1
Illness, injury, bereavement, stress in last 2 years	2.6	3.2	5.9	-1.1	-2.3	0.7	2.4
Medication: Aspirin	1.7	2.3	5.2	-0.3	2.3	0.8	-1.8
Supplements: Vitamin C	1.3	1.6	4.0	1.2	0.4	-0.9	2.0
Knee pain experienced in last month	1.1	1.6	3.3	-0.6	1.8	-0.2	-1.7
Hypertension (Self-reported)	0.2	0.7	1.6	-0.7	-0.7	1.2	-0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.3	0.9	-0.9	0.2	0.5	-0.3
Illnesses of father: Heart disease	0.6	0.8	2.1	1.4	0.5	-0.1	-0.9
Illnesses of siblings: Diabetes	0.6	0.8	1.7	-0.8	0.8	-0.2	-1.3
Smoking status: Previous	0.4	0.7	1.2	0.4	1.1	-1.1	-0.3
Forced expiratory volume in 1-second (FEV1), predicted	0.9	1.8	2.3	-1.3	-1.5	1.2	1.3
Whole body fat-free mass	0.3	1.6	3.0	-1.7	0.4	-1.6	0.7
Leg fat-free mass (right)	0.3	1.7	3.1	-1.8	0.7	-1.7	-0.1
Arm fat percentage (left)	2.1	8.3	24.2	-1.9	1.0	2.2	-4.9
Average weekly red wine intake	0.5	0.7	1.0	1.0	-1.0	-0.9	0.2
Handedness (chirality/laterality): Left-handed	0.9	1.1	2.7	0.8	1.6	1.1	0.1
Mood swings	2.4	4.4	7.7	0.3	2.0	-2.8	-2.4
Loneliness, isolation	1.9	2.7	6.0	0.9	2.5	0.1	-2.0
Long-standing illness, disability or infirmity	0.6	0.8	1.5	-1.2	0.6	-0.3	-1.2
Ever had bowel cancer screening	0.3	0.3	1.0	-0.4	0.1	-0.4	-1.0
Diabetes diagnosed by doctor	0.1	0.2	0.5	0.3	-0.6	0.3	-0.7
Ever had stillbirth, spontaneous miscarriage or termination	1.5	1.6	3.5	0.7	1.3	-0.9	-1.9
Friendships satisfaction	0.3	0.4	1.1	0.2	0.1	-0.7	1.0
Qualifications: nursing, teaching	0.7	1.1	3.1	0.9	0.7	0.1	1.8
Commuting to job workplace: Walk	0.1	0.1	0.2	0.4	-0.4	0.2	-0.0
Eye problems/disorders: Cataract	0.1	0.2	0.3	0.1	-0.4	-0.5	0.5
Mouth/teeth dental problems: Mouth ulcers	0.5	0.8	1.7	1.3	1.2	-0.2	0.4
Medication for cholesterol	1.1	1.7	6.1	-0.6	0.1	-0.6	2.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.5	1.0	-1.0	-0.3	0.2	1.0
Back pain experienced in last month	1.9	2.7	6.6	-0.5	2.6	-1.0	-1.7
Mineral and other dietary supplements	0.9	1.2	1.6	-1.3	-1.0	-0.9	1.1
Breast cancer (self-reported)	0.8	1.0	1.7	0.9	-1.0	-1.3	0.6
Asthma (self-reported)	0.1	0.1	0.3	-0.3	-0.6	0.4	-0.1
Osteoporosis (self-reported)	0.1	0.1	0.3	-0.5	-0.1	0.5	0.3
Osteoarthritis (self-reported)	0.7	0.9	2.5	0.0	1.6	-0.4	-1.0
Medication: Aspirin	1.6	2.0	5.5	-0.4	2.3	0.9	-1.3
Medication: Gliclazide	1.5	1.7	4.7	-2.2	0.2	-0.7	-1.2
Illnesses of father: None of the above (group 1)	1.0	1.2	2.4	-0.3	1.0	-1.6	1.2
Smoking status: Current	1.7	2.7	6.2	-1.2	-1.8	-2.5	0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.9	1.9	4.3	1.3	0.8	1.0	-2.1
Whole body water mass	0.2	1.4	2.8	-1.7	0.3	-1.6	0.5
Leg predicted mass (right)	0.3	1.7	3.1	-1.8	0.7	-1.7	-0.1
Arm fat mass (left)	1.5	6.2	17.5	-2.0	0.9	1.5	-4.2
Number of self-reported non-cancer illnesses	1.2	2.1	6.1	-0.6	1.4	0.5	-2.5
Average weekly champagne plus white wine intake	2.3	3.2	8.1	-0.2	0.9	2.0	2.9
Miserableness	2.0	3.5	6.6	-0.8	2.4	-1.0	-2.6
Guilty feelings	0.7	1.1	1.9	0.0	1.4	-0.7	-1.3
Wears glasses or contact lenses	1.0	1.2	3.7	1.9	0.7	0.6	-0.5
Ever taken oral contraceptive pill	1.6	1.8	3.2	-0.3	1.8	-0.9	1.7
Hearing aid user	1.3	1.5	2.4	-0.5	1.6	-1.0	1.5
Mother’s age at death	0.5	0.7	1.3	1.2	0.0	-0.6	1.0
Financial situation satisfaction	0.7	0.9	1.9	-0.9	0.1	-1.4	-0.9
Tinnitus: Yes, now most or all of the time	1.9	2.2	5.9	-2.4	-0.4	-1.6	-0.7
Commuting to job workplace: Public transport	0.6	0.7	1.9	-0.8	-0.3	-0.3	1.4
Eye problems/disorders: Glaucoma	0.9	1.0	1.8	-0.7	1.4	0.9	-1.0
Medication: Blood pressure	1.2	2.3	4.8	0.7	0.1	1.9	-2.2
Pain type(s) experienced in last month: Hip pain	1.3	1.6	5.4	-0.7	0.0	-2.3	-0.7
Supplements: Fish oil (including cod liver oil)	2.0	2.6	3.2	1.3	1.7	1.6	-1.8
High cholesterol (Self-reported)	1.7	3.1	7.3	-1.1	2.7	0.7	-1.8
Medication: Bendroflumethiazide	2.9	4.3	12.0	-0.7	-0.2	3.5	-2.2
Medication: Paracetamol	1.5	2.4	6.9	-2.6	1.3	-0.4	-0.8
Medication: Lisinopril	0.2	0.2	0.5	-0.7	0.2	0.5	-0.2
Medication: Atorvastatin	1.2	1.4	3.7	0.7	0.9	0.9	-1.9
Illnesses of father: High blood pressure	2.7	3.3	7.6	-2.1	-0.1	2.8	-1.2
Alcohol drinker status: Never	2.0	2.3	3.9	0.3	-1.6	2.0	1.7
Ever smoked	0.9	1.6	5.0	0.2	0.7	-2.2	-0.9
Basal metabolic rate	0.2	1.3	3.9	-2.0	0.3	-1.1	-0.1
Leg fat percentage (left)	1.9	6.9	23.3	-0.8	0.4	1.8	-4.8
Arm fat-free mass (left)	0.1	0.6	1.4	-1.2	0.2	-0.9	-0.3
Number of operations (self-reported)	0.3	0.5	0.7	0.8	0.9	0.1	-0.8
Average weekly beer plus cider intake	0.6	0.8	1.5	-0.1	-0.6	-1.2	-1.2
Irritability	1.8	3.0	6.7	0.6	2.6	-0.9	-2.1
Risk taking	1.2	1.8	2.9	-0.5	1.7	-1.3	-1.5
Ever had prostate specific antigen (PSA) test	1.8	2.1	3.9	1.2	-0.4	-2.0	1.7
Fractured/broken bones in last 5 years	2.7	3.5	6.9	0.4	2.4	-1.0	-2.6
Age started oral contraceptive pill	1.6	2.0	3.9	0.5	2.0	1.9	-0.5
Diastolic blood pressure, automated reading	0.7	2.1	7.4	-2.7	-0.5	0.8	-0.2
Ever depressed for a whole week	1.0	1.3	2.2	0.9	1.4	-1.5	-0.0
Unable to work because of sickness or disability	0.4	0.5	1.1	-0.4	0.9	0.1	-1.1
Commuting to job workplace: Cycle	0.9	1.1	2.6	-0.1	-0.1	1.3	-1.6
Myopia	0.4	0.6	1.9	-0.3	-0.2	0.6	1.4
Vascular/heart problems diagnosed by doctor	0.1	0.3	0.6	-0.3	0.1	-0.8	0.8
Cholesterol lowering medication	2.4	3.6	13.0	0.2	0.9	0.8	-3.6
Medication: Omeprazole (e.g. Zanprol)	0.8	1.0	2.9	-0.9	1.7	0.3	-0.2
Pain experienced in last month	1.3	2.2	5.7	2.4	-1.5	0.4	0.8
Supplements: Calcium	0.3	0.3	0.4	-0.4	0.6	-0.6	0.6
Basal cell carcinoma (self-reported)	1.0	1.1	1.8	1.3	1.2	0.3	1.1
Heart attack/myocardial infarction (self-reported)	1.3	1.7	5.4	0.4	1.0	0.4	-2.3
Deep venous thrombosis (DVT) (self-reported)	2.2	2.9	7.1	1.7	1.2	0.3	-2.7
Heart disease (siblings)	2.5	3.0	9.6	0.5	1.3	0.7	-3.1
Alcohol drinker status: Previous	0.1	0.1	0.2	-0.4	0.0	0.4	-0.4
Pack years of smoking	1.3	1.9	4.2	-1.2	0.7	1.2	-2.1
Impedance of whole body	0.7	3.6	13.0	0.5	-1.1	3.6	0.1
Leg fat mass (left)	1.1	4.4	13.8	-1.3	0.6	1.3	-3.7
Arm predicted mass (left)	0.1	0.6	1.6	-1.2	0.1	-0.8	-0.5