TWAS hub - GALNTL1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0800	0.0380	0.0041	0.019	0.012	0.017	NA	0.021	0.026	0.0630	0.034	NA	0.022
2	TCGA	Brain Lower Grade Glioma	0.0583	0.0274	0.0037	0.011	0.021	0.007	NA	0.006	0.017	0.0018	0.049	NA	0.067
3	TCGA	Stomach Adenocarcinoma	0.0930	0.0420	0.0059	0.001	0.017	0.005	NA	0.005	0.240	0.0200	0.140	NA	0.140

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Frequency of tiredness / lethargy in last 2 weeks	5.9	9.6	11.1	-3.3	-3.2	-2.7
Suffer from ‘nerves’	4.6	7.2	12.0	-3.5	-0.4	-3.1
Diabetes diagnosed by doctor	4.6	7.5	15.7	-1.3	-4.0	-2.3
Chronic bronchitis/emphysema (father)	4.3	5.0	6.0	-2.5	-1.8	-2.4
Frequency of unenthusiasm / disinterest in last 2 weeks	4.0	5.3	15.9	-0.2	-4.0	-0.3
Diabetes (self-reported)	3.8	5.9	12.5	-0.9	-3.5	-2.1
Medication: Lansoprazole	3.8	4.4	10.8	-3.3	-1.3	-0.8
Body Mass Index (BMI) (2010)	3.4	4.7	12.9	1.1	-3.6	-0.3
Sensitivity / hurt feelings	3.4	5.8	6.5	-2.5	-2.5	-2.2
Prospective memory result	3.4	4.1	5.8	-2.4	-2.3	-1.1
Blood Platelet Count	3.3	38.7	85.2	-0.1	9.2	5.6
Medication: Ramipril	3.3	4.2	8.9	-1.1	-3.0	-1.6
Mood swings	3.2	5.8	12.5	-2.1	-3.5	-0.7
Worry (Nagel 2018)	3.1	6.5	13.7	-3.7	-1.8	-1.6
Worrier / anxious feelings	3.1	5.8	13.6	-3.7	-1.6	-1.1
Medication: Metformin	3.0	4.2	11.7	-0.3	-3.4	-1.0
Medication: Amlodipine	3.0	4.2	11.4	1.0	-3.4	-0.5
Breast cancer (self-reported)	3.0	3.6	7.5	-2.7	-1.2	-1.4
Knee pain experienced in last month	2.8	4.3	8.2	-2.1	-2.9	-0.3
Mouth/teeth dental problems: Dentures	2.7	4.6	7.9	-1.6	-1.9	-2.8
Mouth/teeth dental problems	2.6	4.0	7.2	1.9	1.2	2.7
Supplements: Fish oil (including cod liver oil)	2.6	3.4	8.0	1.4	0.3	2.8
Nervous feelings	2.5	4.7	13.9	-3.7	-0.2	-0.3
Comparative body size at age 10	2.5	7.0	17.2	2.0	-4.2	0.1
Medication: Omeprazole (e.g. Zanprol)	2.5	3.0	7.0	-0.1	-1.4	-2.7
Alcohol drinker status: Previous	2.4	2.7	4.4	1.8	-2.1	0.6
Crohns Disease (2017)	2.3	5.0	10.5	-1.3	-1.7	-3.2
Medication: Simvastatin	2.3	3.4	5.2	-0.5	-2.3	-2.2
Neuroticism score	2.3	4.8	7.1	-2.7	-2.7	-0.4
Myopia	2.3	3.3	8.7	-0.0	-3.0	-1.1
Hayfever, allergic rhinitis or eczema	2.2	4.9	6.2	-2.2	1.8	-2.5
Heart attack	2.2	2.9	5.9	-1.2	-2.4	-1.1
Heart attack/myocardial infarction (self-reported)	2.2	2.9	6.8	-0.9	-2.6	-1.1
Neuroticism	2.1	5.1	8.0	-2.7	-2.8	0.1
Pulse rate	2.1	3.5	4.9	-1.1	-2.2	-2.1
Qualifications: nursing, teaching	2.1	3.2	9.6	3.1	0.3	0.1
Cholesterol lowering medication	2.1	3.1	5.9	-0.2	-1.9	-2.4
Frequency of depressed mood in last 2 weeks	2.0	2.8	8.1	-0.7	-2.8	-0.1
Serious illness, injury or assault to yourself	2.0	2.4	3.6	-0.5	-1.9	-1.8
Hair/balding pattern: Pattern 2	2.0	2.6	3.3	-1.8	1.6	-1.4
Hayfever/allergic rhinitis (self-reported)	2.0	2.7	4.6	-1.7	0.7	-2.1
Medication: Cholesterol lowering	2.0	3.1	8.1	-1.0	-2.8	-0.4
Illnesses of father: None of the above (group 1)	2.0	2.4	4.5	-0.8	2.1	-1.4
Average weekly champagne plus white wine intake	2.0	2.8	7.1	0.1	1.2	-2.7
Medication: Co-codamol	1.9	2.1	4.0	-1.2	-1.0	-2.0
Current tobacco smoking	1.9	3.1	3.4	-1.8	-1.8	-1.6
Pain all over the body in last month	1.9	2.0	3.9	-2.0	0.4	-1.4
Arm fat percentage (right)	1.9	7.4	20.4	-1.0	-4.5	-0.8
Body fat percentage	1.9	7.3	20.1	-1.3	-4.5	-0.4
Emphysema/chronic bronchitis	1.9	2.1	5.1	1.0	-2.3	0.4
Number of full sisters	1.9	2.3	4.1	0.9	-1.5	2.0
Leg pain on walking	1.9	2.4	3.1	-1.5	-1.3	-1.8
Average weekly red wine intake	1.9	2.7	7.4	2.7	0.3	0.8
Medication for cholesterol	1.9	2.8	4.0	0.9	2.0	1.9
Mineral and other dietary supplements	1.9	2.6	4.8	-1.7	0.5	-2.2
Pain experienced in last month	1.9	3.1	5.1	2.0	2.2	0.4
Ever unenthusiastic/disinterested for a whole week	1.8	2.2	3.5	1.8	-1.9	-0.0
Illnesses of siblings	1.8	2.5	5.8	-0.2	2.4	1.3
Hair/balding pattern: Pattern 3	1.8	2.7	7.0	0.4	-2.7	1.0
Leg fat percentage (right)	1.8	6.4	17.5	-1.3	-4.2	0.3
Exposure to tobacco smoke outside home	1.8	2.4	6.8	-0.6	-2.6	0.1
Medication: Blood pressure	1.8	3.2	9.6	-0.1	-3.1	-0.1
Alcohol intake frequency.	1.8	4.2	6.6	1.7	-2.6	1.8
Overall health rating	1.8	3.9	11.1	-0.6	-3.3	-0.5
Schizophrenia vs Biploar Disorder	1.7	2.3	4.1	0.2	-2.0	1.6
Primary Biliary Cirrhosis	1.7	2.4	5.2	-1.4	0.0	-2.3
Hand grip strength (left)	1.7	4.4	11.3	-3.4	-0.6	-1.3
Trunk fat percentage	1.7	6.9	18.6	-1.3	-4.3	-0.7
Maternal smoking around birth	1.7	2.5	6.7	-0.4	-2.6	-0.8
Qualifications: A levels/AS levels or equivalent	1.7	3.7	7.8	2.8	1.5	0.9
Mouth/teeth dental problems: Bleeding gums	1.7	2.2	3.3	-1.4	-1.8	-1.2
Whole body fat mass	1.7	7.2	20.2	-1.1	-4.5	-0.4
Leg fat mass (right)	1.7	6.5	18.9	-0.8	-4.3	0.3
Smoking status: Current	1.7	2.7	3.3	-1.6	-1.8	-1.5
Mother’s age at death	1.7	2.1	5.8	-0.6	2.4	0.3
Age started oral contraceptive pill	1.7	2.2	3.2	1.8	1.2	1.4
Depression (Nagel 2018)	1.6	2.4	6.0	-1.0	-2.5	-0.1
Rheumatoid Arthritis	1.6	2.1	2.8	-1.4	-1.7	-1.4
Number of treatments/medications taken	1.6	3.0	3.7	-1.5	-1.9	-1.7
Supplements: Zinc	1.6	1.8	3.7	0.5	1.2	1.9
Trunk fat mass	1.6	7.0	19.8	-1.0	-4.5	-0.3
Qualifications: O levels/GCSEs or equivalent	1.6	2.5	4.0	1.8	2.0	0.6
Pulse wave peak to peak time	1.6	1.9	5.1	0.7	2.3	0.0
Medication: Aspirin	1.6	2.1	6.0	-0.5	-2.4	0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.6	1.9	5.2	-0.5	0.4	-2.3
Leg fat percentage (left)	1.6	5.9	16.1	-1.1	-4.0	0.6
Average weekly beer plus cider intake	1.6	2.3	3.4	-1.9	-1.5	-1.1
Leg fat mass (left)	1.6	6.3	18.4	-0.6	-4.3	0.4
Type 2 Diabetes (T2D) (2018)	1.5	2.8	6.9	-0.7	-2.6	-1.1
Pulse wave Arterial Stiffness index	1.5	1.7	4.5	-0.8	-2.1	0.0
Headache pain in last month	1.5	2.6	5.7	-2.4	-1.2	-0.6
Arm fat percentage (left)	1.5	5.8	17.1	-0.5	-4.1	-0.4
Heart disease (siblings)	1.5	1.9	3.4	1.4	-1.8	-0.6
Illnesses of mother	1.4	1.8	4.2	2.0	-1.0	-0.4
Arm fat mass (right)	1.4	5.6	16.6	-0.3	-4.1	-0.1
Hair/balding pattern: Pattern 4	1.4	3.5	6.3	1.1	-1.7	-2.5
Ever highly irritable/argumentative for 2 days	1.4	1.7	4.7	-0.4	-2.2	0.6
Medication for cholesterol, blood pressure or diabetes	1.4	2.2	6.5	0.3	2.5	0.4
High blood pressure (siblings)	1.4	1.9	5.2	0.5	-2.3	-0.6
Medication: Seretide 50 evohaler	1.4	1.6	2.3	1.4	-1.5	0.6
Loneliness, isolation	1.4	1.9	3.9	-0.2	-2.0	1.3
Mouth/teeth dental problems: Mouth ulcers	1.4	2.2	4.1	0.5	1.5	2.0
Number of self-reported non-cancer illnesses	1.4	2.4	3.6	-1.2	-1.5	-1.9
High cholesterol (Self-reported)	1.4	2.5	5.5	-0.2	-2.4	-1.4
Unable to work because of sickness or disability	1.4	1.9	5.5	0.0	-2.4	-0.3
Bipolar Disorder or Schizophrenia	1.3	3.1	5.9	1.6	0.9	2.4
BMI	1.3	7.4	22.0	0.0	-4.7	-0.3
Diabetes (father)	1.3	1.6	4.5	0.4	-2.1	-0.0
Hypertension (Self-reported)	1.3	3.6	10.1	0.8	-3.2	0.1
Long-standing illness, disability or infirmity	1.3	2.0	2.5	-1.1	-1.5	-1.6
Commuting to job workplace: Walk	1.3	1.4	2.2	-1.0	-1.0	-1.5
Ever depressed for a whole week	1.3	1.6	4.8	0.3	-2.2	-0.2
Schizophrenia (2018)	1.2	2.4	5.5	1.1	0.7	2.3
Prostate Cancer	1.2	1.7	3.0	-1.7	0.1	-1.4
Bipolar Disorder (2011)	1.2	1.2	1.8	-1.3	0.2	-1.3
Lung FEV1/FVC ratio	1.2	5.9	8.5	-1.5	-2.9	-2.7
Other serious medical condition/disability diagnosed by doctor	1.2	1.5	3.1	1.8	-1.2	-0.2
Relative age voice broke	1.2	1.8	2.7	1.4	1.6	0.9
Body mass index (BMI)	1.2	5.1	15.2	0.1	-3.9	-0.0
Waist circumference	1.2	4.5	13.2	-0.4	-3.6	0.1
Had other major operations	1.2	1.5	1.7	-1.2	1.1	-1.3
Qualifications: None of the above	1.2	2.6	4.1	-1.0	-1.7	2.0
Time employed in main current job	1.2	1.4	3.4	-1.9	-0.1	-0.9
Mouth/teeth dental problems: Loose teeth	1.2	1.4	3.1	-0.6	-0.9	-1.8
Illness, injury, bereavement, stress in last 2 years	1.2	1.5	3.9	-0.1	2.0	0.7
Osteoarthritis (self-reported)	1.2	1.5	4.4	0.4	-2.1	-0.1
Medication: Aspirin	1.2	1.6	4.3	-0.6	-2.1	0.4
Alcohol drinker status: Never	1.2	1.5	2.6	0.3	-1.6	1.4
Vascular/heart problems diagnosed by doctor	1.2	3.2	9.4	0.2	3.1	0.5
Major Depression (MDD)	1.1	1.4	3.7	0.6	-0.1	1.9
Ovarian Cancer	1.1	1.4	2.8	0.4	1.7	-1.1
High blood pressure	1.1	3.2	9.1	0.6	-3.0	0.2
Number of full brothers	1.1	1.4	3.2	-1.8	-0.5	0.8
Qualifications: College or University degree	1.1	3.6	7.3	2.7	1.9	0.0
Mean time to correctly identify matches	1.1	2.0	5.5	2.4	-0.4	0.6
Illnesses of father: Heart disease	1.1	1.6	3.7	1.0	-1.9	0.1
Arm fat mass (left)	1.1	4.5	13.5	-0.4	-3.7	0.1
Guilty feelings	1.1	1.7	3.3	-1.2	-0.6	1.8
Neuroticism (Nagel 2018)	1.0	2.4	3.8	-1.9	-1.8	0.0
Verbal and Numeric Reasoning (VNR)	1.0	2.3	5.9	0.0	1.0	-2.4
Coronary Artery Disease (CAD)	1.0	1.2	3.2	-0.4	1.8	0.3
Cardiovascular Disease	1.0	3.3	9.7	0.2	-3.1	-0.4
Fed-up feelings	1.0	1.7	4.0	-1.1	-2.0	0.1
Age when periods started (menarche)	1.0	2.4	3.6	-1.9	0.9	-1.7
Alcohol usually taken with meals	1.0	1.6	2.4	1.4	1.6	-0.7
Migraine (self-reported)	1.0	1.2	3.1	-1.8	-0.1	-0.8
Eye problems/disorders: Glaucoma	1.0	1.1	3.1	-0.5	1.8	0.2
Medication: Bendroflumethiazide	1.0	1.5	3.4	-0.7	-1.8	-0.7
Schizophrenia (2014)	0.9	1.9	4.7	0.9	0.6	2.2
Heel bone mineral density (BMD) T-score, automated (right)	0.9	2.1	4.2	0.4	1.4	2.0
Allergy	0.9	2.0	2.9	1.1	-1.7	1.5
Fluid intelligence score	0.9	1.8	3.1	0.9	1.8	-1.2
Depression (self-reported)	0.9	1.1	2.3	0.9	-1.5	-0.2
Health satisfaction	0.9	1.2	2.8	0.5	-1.7	-0.7
Pulse rate, automated reading	0.9	2.8	5.2	-1.2	-2.3	-1.3
Back pain experienced in last month	0.9	1.3	2.3	-1.5	-1.0	-0.8
Osteoporosis (self-reported)	0.9	1.1	1.8	1.2	1.4	0.2
Commuting to job workplace: Public transport	0.9	1.1	1.3	0.9	1.0	1.1
Pack years of smoking	0.9	1.3	1.8	1.4	-0.8	1.2
Depressed Affect (Nagel 2018)	0.8	1.7	4.1	-1.0	-2.0	0.1
Lung FVC	0.8	4.3	7.1	2.7	0.9	2.2
Severe depression (siblings)	0.8	0.9	2.2	1.5	0.6	-0.2
Hand grip strength (right)	0.8	2.3	6.7	-2.6	-0.1	-0.3
Townsend deprivation index at recruitment	0.8	1.2	3.3	0.2	-1.8	-0.4
Tinnitus: Yes, but not now, but have in the past	0.8	0.9	2.2	-0.3	-1.5	-0.6
Qualifications: CSEs or equivalent	0.8	1.1	2.5	-0.7	1.6	-0.4
Happiness	0.8	1.0	2.5	1.6	-0.2	0.7
Exposure to tobacco smoke at home	0.8	0.9	2.4	0.6	-1.5	0.2
Reason for reducing amount of alcohol drunk: Health precaution	0.8	0.9	2.0	0.7	-0.5	-1.4
Shortness of breath walking on level ground	0.8	0.9	1.7	1.0	-1.3	0.1
Chest pain or discomfort	0.8	1.1	1.8	-1.3	-1.0	-0.8
Commuting to job workplace: Car/motor vehicle	0.8	0.9	2.1	0.4	-0.8	-1.4
Irritability	0.8	1.4	2.3	0.4	-1.3	1.5
Intelligence (Savage-Jansen 2018)	0.7	2.0	3.3	-0.2	1.7	-1.8
Systolic Blood Pressure	0.7	3.5	5.9	-2.4	0.1	-2.2
Allergy or Eczema	0.7	1.9	2.9	-0.9	1.4	-1.7
Average weekly spirits intake	0.7	0.9	2.1	-1.5	-0.7	0.1
Systolic blood pressure, automated reading	0.7	2.0	3.3	-1.2	1.1	-1.8
Impedance of leg (right)	0.7	3.6	8.0	-2.8	1.6	0.3
Taking other prescription medications	0.7	1.0	1.3	-1.1	-0.7	-1.2
Impedance of leg (left)	0.7	3.4	7.2	-2.7	1.6	0.6
Weight	0.7	3.5	10.4	-0.3	-3.2	-0.0
Hip circumference	0.7	3.0	8.7	-0.4	-2.9	-0.4
Serious illness, injury or assault of a close relative in last 2 years	0.7	0.8	1.8	1.4	0.7	0.5
Length of working week for main job	0.7	0.8	1.2	-0.3	-1.0	-1.1
Chronic bronchitis/emphysema (mother)	0.7	0.8	1.7	1.3	-0.6	0.7
Medication for pain relief, constipation, heartburn	0.7	1.3	2.8	1.7	0.9	0.5
Neck or shoulder pain in last month	0.7	1.0	2.6	-0.6	-1.6	-0.3
Medication: Allopurinol	0.7	1.0	1.6	-1.2	-0.2	-1.1
Ever had stillbirth, spontaneous miscarriage or termination	0.7	0.7	1.7	1.3	-0.7	0.0
Medication: Gliclazide	0.7	0.8	2.1	0.2	-1.4	-0.5
Wears glasses or contact lenses	0.7	0.8	2.5	0.0	1.6	0.1
Bipolar Disorder (2018)	0.6	0.9	1.3	1.1	0.8	1.0
Reaction Time	0.6	1.2	3.3	1.8	0.3	0.5
Mean Putamen Volume	0.6	0.7	1.9	-0.2	0.5	1.4
Relative age of first facial hair	0.6	1.3	3.3	0.5	1.8	0.6
Stomach or abdominal pain in last month	0.6	0.7	1.7	-0.4	-0.4	-1.3
Supplements: Glucosamine	0.6	0.8	1.9	1.4	0.2	0.7
Forced vital capacity (FVC)	0.6	2.1	2.8	1.7	0.9	1.7
Father’s age at death	0.6	0.8	2.1	-0.1	1.4	0.6
Tense / ‘highly strung’	0.6	1.0	2.3	-0.4	-1.5	0.7
Gout (self-reported)	0.6	0.9	2.2	-0.6	0.0	-1.5
Illnesses of siblings: Diabetes	0.6	0.8	1.6	-0.9	-1.3	0.2
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.2	2.7	-1.6	-0.3	-0.9
Medication: Atorvastatin	0.6	0.7	1.5	0.8	-1.2	0.0
Risk taking	0.6	0.9	2.1	0.7	-1.5	0.3
Ever had prostate specific antigen (PSA) test	0.6	0.7	1.8	1.4	-0.5	0.1
Impedance of whole body	0.6	2.8	4.3	-2.1	2.0	-0.4
Alzheimer’s Disease (in mother)	0.5	0.5	1.5	-0.4	1.2	0.1
Breast Cancer	0.5	1.1	2.2	-0.7	-0.8	-1.5
Crohns Disease (2012)	0.5	0.8	2.2	0.4	0.1	-1.5
Fasting Glucose	0.5	0.6	1.6	-0.2	0.3	-1.3
Lupus	0.5	0.7	1.5	-0.3	0.7	1.2
Hearing difficulty/problems: Yes	0.5	0.8	1.4	0.9	-1.2	-0.4
Pack years adult smoking proportion	0.5	0.7	0.8	0.9	-0.7	0.8
Average weekly fortified wine intake	0.5	0.6	1.0	0.5	1.0	0.8
Medication: Levothyroxine sodium	0.5	0.9	1.8	-1.4	1.0	0.1
High blood pressure (mother)	0.5	0.8	2.2	-1.5	-0.1	-0.1
Noisy workplace	0.5	0.6	1.3	-1.1	-0.5	-0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.8	1.6	-1.3	-0.1	-0.8
Medication: Paracetamol	0.5	0.8	1.4	-1.2	-0.9	-0.3
Wheeze or whistling in the chest in last year	0.5	0.9	1.4	0.7	-1.2	-0.8
Eye problems/disorders: None of the above	0.5	0.5	1.3	1.1	-0.4	-0.3
Medication: Omeprazole	0.5	0.6	1.1	1.1	-0.5	-0.7
Friendships satisfaction	0.5	0.7	1.3	1.2	-0.7	0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.0	1.5	-0.8	-1.0	-1.2
Medication: Lisinopril	0.5	0.7	1.0	0.9	-1.0	-0.5
Commuting to job workplace: Cycle	0.5	0.6	1.4	0.5	1.2	0.2
Supplements: Calcium	0.5	0.6	1.7	0.0	-0.1	1.3
Irritable Bowel Disease (IBD)	0.4	1.1	2.3	-0.3	-0.9	-1.5
HbA1C	0.4	0.5	1.0	-0.1	1.0	0.7
Neuroticism (2016)	0.4	0.6	1.5	-0.4	-0.2	1.2
Triglycerides	0.4	0.7	1.6	-0.2	-1.3	0.6
Blood Red Count	0.4	3.8	7.9	-2.8	1.5	1.1
Smoking Status	0.4	1.0	1.4	-1.2	-0.9	-0.9
Ever had hysterectomy (womb removed)	0.4	0.4	1.2	0.1	1.1	0.4
Heel bone mineral density (BMD) T-score, automated (left)	0.4	0.9	1.8	0.5	0.9	1.3
Medication: Atenolol	0.4	0.5	1.2	0.1	-1.1	-0.5
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.7	1.6	-0.5	-1.3	0.4
Hearing difficulty/problems with background noise	0.4	0.7	1.0	0.4	-1.0	-1.0
Impedance of arm (right)	0.4	1.9	3.2	-1.8	1.3	-0.9
Alcohol intake versus 10 years previously	0.4	0.6	1.1	-0.6	-1.0	-0.5
Lung cancer (father)	0.4	0.5	0.9	-1.0	-0.8	-0.1
Impedance of arm (left)	0.4	1.7	3.6	-1.1	1.9	-0.4
Birth weight of first child	0.4	0.7	1.1	0.8	1.1	0.6
Glaucoma (self-reported)	0.4	0.4	1.2	-0.4	1.1	-0.1
Number of children fathered	0.4	0.5	0.7	-0.7	0.6	0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.4	1.2	1.1	0.2	0.3
Had major operations	0.4	0.5	1.3	0.2	-1.1	-0.2
Supplements: Vitamin C	0.4	0.5	0.8	0.9	0.4	0.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.4	1.0	0.1	1.0	0.6
Miserableness	0.4	0.7	1.3	-0.8	-1.2	-0.4
Ever taken oral contraceptive pill	0.4	0.4	0.8	-0.4	-0.9	-0.5
Tinnitus: Yes, now most or all of the time	0.4	0.5	0.8	-0.9	0.7	-0.5
Ever smoked	0.4	0.7	1.5	-1.2	0.5	-0.5
Alzheimer’s Disease (in father)	0.3	0.4	0.6	0.7	0.3	0.7
Ulcerative Colitis	0.3	0.4	1.3	0.2	1.1	0.1
Blood White Count	0.3	1.9	4.3	-1.2	2.1	-0.1
Heel T-Score	0.3	2.6	4.1	2.0	1.0	1.7
Ever used hormone-replacement therapy (HRT)	0.3	0.4	1.0	1.0	0.4	0.3
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	0.6	0.2	-0.8	0.7
Medication for hormone replacement therapy	0.3	0.4	0.9	-0.0	-1.0	-0.5
Vitamin and mineral supplements	0.3	0.4	1.1	-0.2	-0.0	-1.0
Diabetes (mother)	0.3	0.4	1.2	0.1	0.1	1.1
Leg fat-free mass (left)	0.3	1.8	5.2	0.3	-2.3	-0.4
Bilateral oophorectomy (both ovaries removed)	0.3	0.3	0.5	0.7	-0.5	-0.5
Leg predicted mass (left)	0.3	1.8	5.2	0.4	-2.3	-0.3
Number of live births	0.3	0.5	1.1	-1.0	0.6	-0.0
Forced expiratory volume in 1-second (FEV1)	0.3	0.9	1.5	1.2	0.5	1.0
Asthma	0.3	0.6	1.8	0.1	1.3	0.2
Hypothyroidism/myxoedema (self-reported)	0.3	0.6	1.2	-0.7	1.1	-0.2
Forced vital capacity (FVC), Best measure	0.3	1.2	1.8	0.6	1.3	1.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	1.1	-0.3	-1.0	-0.3
Arm predicted mass (right)	0.3	1.7	4.1	0.7	-2.0	0.6
Leg fat-free mass (right)	0.3	1.4	3.8	0.6	-2.0	-0.2
Ever had bowel cancer screening	0.3	0.3	0.5	0.2	-0.7	-0.6
Asthma (self-reported)	0.3	0.6	1.8	0.2	1.3	0.2
Leg predicted mass (right)	0.3	1.5	4.0	0.8	-2.0	-0.2
Medication: Blood pressure	0.3	0.6	1.1	-0.3	-1.0	-0.7
Pain type(s) experienced in last month: Hip pain	0.3	0.4	1.3	-0.0	-1.1	-0.1
Basal metabolic rate	0.3	1.6	4.9	0.1	-2.2	0.0
Number of operations (self-reported)	0.3	0.5	1.1	-0.6	0.0	-1.1
Arm predicted mass (left)	0.3	1.7	4.7	0.4	-2.2	0.4
Age at First Birth	0.2	0.3	0.5	0.6	0.2	0.7
Respiratory disease	0.2	0.5	1.1	0.6	1.0	0.3
Angina	0.2	0.2	0.5	-0.3	0.4	-0.7
Number of incorrect matches in round	0.2	0.3	0.6	-0.7	-0.5	0.5
Had menopause	0.2	0.2	0.5	0.3	-0.7	-0.2
Financial difficulties in last 2 years	0.2	0.3	0.8	-0.2	-0.9	-0.3
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.3	0.5	-0.7	0.1	-0.7
Peak expiratory flow (PEF)	0.2	0.5	0.9	0.7	-1.0	0.0
Pulse wave reflection index	0.2	0.3	0.8	0.3	-0.0	0.9
Blood clot in the leg (DVT)	0.2	0.3	0.7	0.2	0.1	0.9
Medication: Ventolin 100micrograms inhaler	0.2	0.2	0.6	0.8	0.1	0.4
Arm fat-free mass (right)	0.2	1.0	2.4	0.6	-1.5	0.6
Worry too long after embarrassment	0.2	0.3	0.4	-0.6	-0.4	0.6
Angina (self-reported)	0.2	0.3	0.6	-0.5	0.3	-0.8
Medication: Ibuprofen	0.2	0.3	0.5	-0.7	0.6	0.1
Smoking status: Previous	0.2	0.2	0.3	-0.5	0.5	0.4
Whole body fat-free mass	0.2	1.1	3.2	0.4	-1.8	0.0
Handedness (chirality/laterality): Left-handed	0.2	0.3	0.4	-0.5	0.6	-0.3
Whole body water mass	0.2	1.2	3.6	0.4	-1.9	0.1
Financial situation satisfaction	0.2	0.2	0.5	-0.1	-0.5	0.7
Medication: Paracetamol	0.2	0.4	1.0	-1.0	-0.3	0.2
Illnesses of father: High blood pressure	0.2	0.2	0.4	-0.5	0.7	0.1
Arm fat-free mass (left)	0.2	1.3	3.7	0.1	-1.9	0.3
Fractured/broken bones in last 5 years	0.2	0.3	0.7	0.2	0.2	0.9
Diastolic blood pressure, automated reading	0.2	0.6	1.6	-1.3	0.3	-0.2
Deep venous thrombosis (DVT) (self-reported)	0.2	0.3	0.8	0.1	0.2	0.9
Alzheimer’s Disease (including proxy)	0.1	0.1	0.2	-0.0	0.5	0.1
Ulcerative Colitis (UC)	0.1	0.2	0.3	0.4	0.5	0.5
HDL Cholesterol	0.1	0.2	0.3	0.5	-0.5	-0.4
LDL Cholesterol	0.1	0.1	0.2	-0.0	-0.4	0.4
Blood Eosinophil Count	0.1	0.7	1.3	1.1	0.7	-0.5
Waist Hip Ratio (WHR)	0.1	0.6	0.9	-1.0	-0.8	-0.3
Chronotype (morning person)	0.1	0.3	0.6	0.3	0.8	0.5
Tanning	0.1	1.1	2.0	0.2	-1.1	1.4
Multivitamins +/- minerals	0.1	0.1	0.1	-0.2	-0.3	0.4
Diverticular disease/diverticulitis (self-reported)	0.1	0.1	0.4	-0.1	0.6	0.1
Past tobacco smoking	0.1	0.1	0.2	0.4	-0.1	-0.5
Trunk fat-free mass	0.1	0.6	1.8	0.3	-1.3	0.1
Falls in the last year	0.1	0.2	0.3	0.4	0.5	-0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.3	0.7	0.2	0.8	0.4
Trunk predicted mass	0.1	0.6	1.7	0.4	-1.3	0.2
Breastfed as a baby	0.1	0.1	0.3	-0.2	0.5	0.2
Loud music exposure frequency	0.1	0.1	0.2	0.4	-0.2	-0.4
Birth weight	0.1	0.1	0.3	0.0	0.2	0.5
Age at first live birth	0.1	0.2	0.6	0.8	-0.3	0.1
Comparative height size at age 10	0.1	0.3	0.9	0.3	-0.1	0.9
Age at last live birth	0.1	0.1	0.2	-0.1	0.5	0.0
Family relationship satisfaction	0.1	0.2	0.3	0.4	0.5	0.2
Hearing aid user	0.1	0.2	0.2	0.2	0.5	-0.4
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.1	-0.2	-0.2	-0.2
Height	0.0	0.9	1.5	-0.6	1.2	0.9
Hypothyroidism (self reported)	0.0	0.0	0.1	-0.3	0.1	-0.1
Hair Pigment	0.0	0.1	0.2	0.2	0.1	-0.5
Sitting height	0.0	0.3	0.6	-0.7	-0.1	-0.5
Standing height	0.0	0.5	1.0	-0.6	1.0	0.1
Heart disease (mother)	0.0	0.0	0.0	-0.1	-0.1	-0.2
Qualifications: NVQ or HND or HNC or equivalent	0.0	0.0	0.1	-0.1	-0.4	0.1
Eye problems/disorders: Cataract	0.0	0.1	0.1	0.1	0.2	0.4
Basal cell carcinoma (self-reported)	0.0	0.0	0.1	-0.1	0.1	0.2

Hub : Genes

GALNTL1

Models

Trait associations