TWAS hub - GAS2L1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0420	0.0190	6.2e-03	0.021	0.013	0.013	NA	0.019	1.1e-03	9.7e-03	8.4e-03	NA	2.1e-03
2	GTEx	Artery Aorta	0.1840	0.0640	3.1e-04	0.109	NA	0.057	NA	0.088	1.3e-06	NA	4.6e-04	NA	1.5e-05
3	GTEx	Artery Tibial	0.1307	0.0490	3.3e-03	-0.003	NA	-0.003	NA	-0.004	8.1e-01	NA	9.0e-01	NA	9.6e-01
4	GTEx	Brain Cerebellar Hemisphere	0.4100	0.1040	3.3e-04	0.231	NA	0.273	NA	0.248	1.3e-06	NA	1.1e-07	NA	4.8e-07
5	GTEx	Brain Cerebellum	0.4420	0.0930	2.7e-05	0.141	NA	0.319	NA	0.333	5.9e-05	NA	3.9e-10	NA	1.3e-10
6	GTEx	Brain Hypothalamus	0.3530	0.1080	4.3e-03	0.168	NA	0.077	NA	0.102	9.5e-05	NA	7.4e-03	NA	2.2e-03
7	GTEx	Brain Nucleus accumbens basal ganglia	0.3580	0.1160	1.0e-03	-0.008	NA	0.099	NA	0.035	6.3e-01	NA	1.3e-03	NA	4.2e-02
8	METSIM	Adipose	0.0505	0.0212	8.8e-04	0.015	0.007	0.009	0.008	0.013	2.0e-03	3.1e-02	1.5e-02	0.019	4.1e-03
9	TCGA	Brain Lower Grade Glioma	0.0598	0.0328	6.7e-03	0.003	0.019	0.024	NA	0.012	1.2e-01	2.6e-03	7.5e-04	NA	1.3e-02
10	TCGA	Prostate Adenocarcinoma	0.0417	0.0234	1.9e-04	0.024	0.042	0.035	NA	0.032	1.4e-03	2.8e-05	1.2e-04	NA	2.6e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Commuting to job workplace: Cycle	4.1	5.0	9.4	2.6	2.6	0.2	2.9	1.7	3.1	2.3	0.5	1.7	2.8
Number of operations (self-reported)	3.6	5.3	13.5	3.2	2.8	-1.6	0.9	2.3	2.7	1.9	1.2	0.7	3.7
Mouth/teeth dental problems: Loose teeth	3.5	4.1	8.9	2.5	2.7	1.5	2.5	1.8	2.0	1.3	0.3	0.9	3.0
Had major operations	3.3	3.8	7.3	2.7	2.2	0.8	1.2	2.2	2.4	1.3	1.4	1.7	2.7
Commuting to job workplace: Walk	3.2	3.5	8.9	1.7	2.5	0.9	1.6	1.5	1.5	3.0	0.4	1.5	2.6
Alcohol drinker status: Previous	3.2	3.6	6.9	-1.7	-2.2	-1.7	-2.6	-1.9	-1.4	-2.3	-0.8	-1.2	-2.2
Medication: Metformin	2.9	4.2	13.6	-1.6	-1.1	3.7	-2.6	-1.9	-2.2	1.2	0.1	-2.2	-1.5
Commuting to job workplace: Car/motor vehicle	2.7	3.1	8.1	-1.6	-2.6	-0.7	-1.3	-2.8	-1.0	-1.3	0.5	-1.2	-2.6
Schizophrenia vs Biploar Disorder	2.5	3.3	6.7	-1.7	-2.3	-0.0	-2.1	-2.6	-0.6	-1.2	-1.8	-2.1	-2.1
Heel T-Score	2.5	20.2	46.0	-5.6	-6.8	-1.4	-3.5	-3.8	-3.2	-6.1	-3.0	-2.8	-5.6
Lung FEV1/FVC ratio	2.5	12.5	49.4	-2.4	-4.5	-3.6	-3.2	-3.4	-0.9	-7.0	0.4	-1.5	-3.2
Tense / ‘highly strung’	2.5	4.1	11.1	2.8	2.6	-0.9	1.6	2.5	1.4	0.5	1.0	1.7	3.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.4	5.1	9.9	-2.6	-2.9	-1.4	-1.6	-1.4	-2.2	-2.9	-1.5	-1.9	-3.2
Bipolar Disorder (2018)	2.2	3.5	8.0	1.6	1.9	1.6	2.2	2.8	0.8	0.9	1.0	2.8	1.8
Nervous feelings	2.2	4.1	11.4	2.7	3.2	-1.6	1.6	1.8	1.5	0.7	-0.3	1.1	3.4
Asthma	2.2	4.4	7.8	2.6	2.7	-1.8	2.5	2.2	2.2	0.8	0.8	1.3	2.8
Medication for pain relief, constipation, heartburn	2.2	3.8	10.3	2.2	1.9	0.9	1.8	2.8	2.0	-0.1	0.4	3.2	1.9
Medication: Lisinopril	2.2	2.8	6.2	2.2	1.7	1.5	1.6	0.5	1.7	2.5	1.6	-0.8	1.9
Type 2 Diabetes (T2D) (2018)	2.1	4.0	12.7	-1.6	-1.1	3.6	-1.8	-1.5	-2.6	-0.0	-1.1	-2.4	-1.9
Medication: Co-codamol	2.1	2.4	6.4	-1.4	-1.9	0.7	-1.9	-2.2	-0.8	0.7	-0.2	-2.5	-1.3
Multivitamins +/- minerals	2.1	2.6	6.7	-1.3	-2.3	0.3	-2.6	-2.2	-0.4	-0.7	-0.9	-2.0	-1.4
Pain all over the body in last month	2.1	2.2	5.8	-1.8	-1.0	0.2	-1.9	-1.6	-2.4	-0.8	-1.6	-0.7	-1.6
Asthma (self-reported)	2.1	4.2	7.7	2.6	2.7	-1.9	2.2	2.1	2.2	0.8	0.9	1.3	2.8
Heart disease (siblings)	2.1	2.5	5.4	-2.2	-1.6	0.3	-1.5	-1.7	-2.3	0.3	-1.1	-1.5	-2.0
Blood Platelet Count	2.0	23.8	80.8	1.6	6.2	-0.8	6.3	9.0	-0.1	3.8	0.2	6.7	4.2
Respiratory disease	2.0	4.5	8.3	2.5	2.9	-0.2	2.6	2.3	2.4	1.9	0.4	0.9	2.8
Glaucoma (self-reported)	2.0	2.3	4.6	-2.0	-1.2	0.3	-0.9	-1.1	-2.1	0.6	-2.1	-2.1	-1.4
Hair/balding pattern: Pattern 4	1.9	4.5	22.3	-2.3	-0.7	3.1	-0.9	-0.7	-4.7	-0.3	-1.6	0.3	-1.9
Medication: Aspirin	1.9	2.5	5.2	-1.7	-1.7	0.4	-2.0	-2.3	-1.4	-0.4	0.3	-2.3	-1.7
Ever had bowel cancer screening	1.9	2.3	6.1	1.8	2.1	0.3	1.7	1.6	1.4	1.3	0.5	0.0	2.5
Commuting to job workplace: Public transport	1.9	2.3	5.7	1.8	2.0	1.1	0.9	1.7	1.6	1.4	-0.4	0.4	2.4
Worry (Nagel 2018)	1.7	3.6	10.8	2.6	2.3	-2.1	1.1	1.2	2.1	0.2	0.3	0.9	3.3
Diabetes (self-reported)	1.7	2.6	6.3	-1.2	-1.0	2.5	-1.7	-1.7	-1.8	0.5	-0.8	-2.5	-1.1
Diabetes diagnosed by doctor	1.7	2.8	7.3	-1.2	-1.0	2.6	-1.8	-1.8	-1.7	0.4	-0.7	-2.7	-1.3
Medication: Aspirin	1.7	2.2	5.1	-1.4	-1.6	0.6	-1.8	-2.3	-1.2	-0.3	0.9	-2.0	-1.7
Guilty feelings	1.7	2.6	6.5	1.9	1.7	0.5	2.0	0.9	1.6	2.6	-0.2	0.8	2.2
Bipolar Disorder or Schizophrenia	1.6	3.8	6.9	1.9	2.2	1.1	2.6	2.6	0.7	2.1	0.6	2.2	2.2
Waist Hip Ratio (WHR)	1.6	7.3	18.2	2.2	2.9	3.1	4.3	1.3	2.5	3.4	2.2	1.5	2.4
Chronotype (morning person)	1.6	3.7	9.0	2.5	3.0	-1.8	1.6	1.3	2.4	0.4	-0.1	0.6	2.8
Sensitivity / hurt feelings	1.6	2.7	5.6	1.5	2.4	-1.7	1.7	2.2	0.0	-1.7	-0.9	-0.1	2.2
Medication: Ventolin 100micrograms inhaler	1.6	2.0	3.9	1.3	1.4	1.7	1.6	1.2	1.4	2.0	1.0	0.7	1.4
Worry too long after embarrassment	1.6	2.7	6.9	2.4	1.9	-0.5	0.8	1.1	1.9	0.9	1.4	1.5	2.6
Migraine (self-reported)	1.6	1.9	3.7	-1.7	-1.6	-1.6	-0.8	-1.5	-1.9	-1.5	-0.5	-0.3	-1.6
Mean Putamen Volume	1.5	1.7	3.5	1.5	1.9	0.5	0.6	1.2	1.3	1.5	1.7	1.2	1.2
Hearing difficulty/problems: Yes	1.5	2.3	6.8	-0.7	-1.0	-0.3	-2.0	-2.5	-0.1	2.6	-0.7	-1.8	-0.7
Forced expiratory volume in 1-second (FEV1), Best measure	1.5	4.7	11.0	-2.3	-3.3	-1.1	-2.7	-2.5	-1.4	-1.7	-0.8	-1.3	-3.0
Birth weight of first child	1.5	2.7	6.1	2.1	1.7	0.6	1.7	0.8	2.5	2.2	0.4	0.8	1.9
Eye problems/disorders: Glaucoma	1.5	1.7	5.9	-1.9	-0.9	0.2	-0.3	0.0	-1.9	-0.3	-2.4	-1.3	-1.2
HbA1C	1.4	1.5	5.2	1.2	2.3	-0.6	1.1	1.0	0.7	0.7	-0.4	1.7	1.5
Other serious medical condition/disability diagnosed by doctor	1.4	1.9	4.5	-1.2	-1.0	-1.6	-1.4	-0.6	-1.6	-0.6	-2.1	-2.0	-0.4
Systolic blood pressure, automated reading	1.4	3.9	11.0	2.2	1.8	2.2	1.8	0.2	0.9	3.3	2.5	0.6	2.2
Diabetes (mother)	1.4	1.7	10.4	0.1	1.0	3.2	0.9	0.0	-0.3	2.1	-0.3	-0.0	0.7
Worrier / anxious feelings	1.4	2.6	12.9	1.3	1.5	-3.6	0.5	1.0	1.0	-0.9	-0.9	0.1	2.3
Qualifications: A levels/AS levels or equivalent	1.4	3.1	5.3	1.9	1.7	-0.3	1.8	1.3	2.2	2.3	1.5	1.6	2.1
Lung cancer (father)	1.4	1.6	3.8	1.3	1.2	-2.0	0.8	0.6	1.1	0.7	1.9	1.4	0.9
Chronic bronchitis/emphysema (mother)	1.4	1.7	9.7	-0.7	0.4	-3.1	-0.2	0.0	-1.0	0.8	-1.6	-1.4	-0.0
Age at first live birth	1.4	2.6	4.9	1.4	1.7	1.2	1.6	1.8	1.4	0.6	-1.8	2.2	1.7
Pack years of smoking	1.4	2.1	5.2	2.3	1.5	0.7	0.4	0.2	1.7	1.1	1.0	-1.7	2.2
Ulcerative Colitis (UC)	1.3	2.4	8.8	-2.0	-1.0	1.1	-0.9	-0.7	-1.8	-0.1	-3.0	-1.0	-1.9
Age at First Birth	1.3	1.9	6.5	0.9	1.4	0.9	0.9	1.3	0.4	2.5	0.3	2.2	1.1
Type 2 Diabetes (T2D) (2012)	1.3	1.5	3.8	1.3	1.3	1.9	1.1	0.4	1.0	1.5	1.3	0.5	0.8
Diabetes (father)	1.3	1.6	3.8	1.0	1.4	1.9	1.9	0.8	0.5	1.5	0.3	0.3	1.4
Pack years adult smoking proportion	1.3	2.0	4.6	2.1	1.5	0.9	0.5	0.0	1.6	1.1	0.8	-1.7	2.1
Heart attack	1.3	1.7	4.2	1.6	1.0	0.3	0.0	-0.8	1.9	1.8	2.0	0.5	1.1
Exposure to tobacco smoke outside home	1.3	1.8	4.6	-1.6	-1.2	-0.5	-2.1	-1.1	-1.7	-1.1	-1.1	-1.2	-0.9
Eye problems/disorders: Cataract	1.3	1.5	4.2	0.8	1.5	2.1	1.6	1.5	0.0	0.9	-0.5	0.3	1.4
Mouth/teeth dental problems: Mouth ulcers	1.3	2.0	5.0	1.5	2.2	-0.7	1.2	2.1	0.3	0.5	0.8	1.5	1.9
Illnesses of father: High blood pressure	1.3	1.7	8.4	0.8	-0.2	-0.9	-0.6	-1.8	0.8	1.0	-0.1	-2.9	1.2
Medication: Omeprazole (e.g. Zanprol)	1.3	1.6	5.3	-0.0	-1.1	-1.5	-1.5	-2.3	0.0	-0.4	-0.5	-2.2	-0.2
Primary Biliary Cirrhosis	1.2	1.7	4.6	0.2	-1.4	-1.7	-2.1	-2.0	0.3	-0.3	1.0	-1.6	-0.5
Relative age of first facial hair	1.2	2.5	10.6	0.1	-0.3	-3.3	-2.1	-0.9	-0.0	1.4	0.0	-2.6	0.8
Maternal smoking around birth	1.2	1.7	4.2	-0.6	-1.2	-0.4	-2.0	-2.0	-1.2	0.0	2.0	-0.2	-1.1
Medication: Simvastatin	1.2	1.7	4.1	1.2	-0.1	0.8	-0.5	-1.5	1.5	1.6	2.0	-1.8	0.9
Happiness	1.2	1.4	3.9	1.8	1.3	-0.1	0.8	0.7	1.5	1.4	0.5	-0.2	2.0
Mouth/teeth dental problems: Dentures	1.2	1.9	4.5	-1.8	-1.6	1.7	-0.4	-1.9	-1.0	-1.0	0.0	-0.9	-2.1
Ever highly irritable/argumentative for 2 days	1.2	1.4	3.8	0.7	-0.3	-1.8	-0.8	-1.4	1.2	-0.2	-1.1	-2.0	0.8
Number of children fathered	1.2	1.4	4.2	-0.3	0.2	0.7	1.6	1.5	-0.9	-1.6	-2.0	-0.4	-0.4
Eye problems/disorders: None of the above	1.2	1.4	5.1	0.6	-1.0	-2.3	-1.1	-1.0	1.7	-0.3	1.6	0.0	-0.0
Medication: Omeprazole	1.2	1.4	5.3	0.6	-0.9	-1.5	-1.3	-2.3	0.6	-0.2	0.1	-1.8	0.2
Breast cancer (self-reported)	1.2	1.4	3.4	-1.1	-1.9	-1.4	-1.2	-1.2	-0.5	-0.1	-0.5	-1.5	-1.3
Wears glasses or contact lenses	1.2	1.3	3.2	1.5	0.8	-0.5	1.6	1.4	1.0	1.3	0.1	0.1	1.8
Medication: Bendroflumethiazide	1.2	1.7	8.1	0.3	0.4	2.1	0.4	0.2	-1.1	1.8	2.9	0.4	0.0
Heart attack/myocardial infarction (self-reported)	1.2	1.5	3.8	1.5	1.0	-0.1	0.0	-0.8	1.8	2.0	1.7	0.2	1.0
Reaction Time	1.1	2.1	4.1	1.1	1.4	-2.0	0.7	1.2	1.1	-2.0	-0.3	1.6	2.0
Number of treatments/medications taken	1.1	1.9	5.6	-0.3	-0.7	-1.4	-1.2	-2.2	-0.8	1.9	0.7	-2.4	-0.1
Bilateral oophorectomy (both ovaries removed)	1.1	1.3	3.3	1.8	1.4	0.2	0.4	0.6	0.6	1.1	1.8	0.5	1.4
Heel bone mineral density (BMD) T-score, automated (left)	1.1	2.5	6.0	-1.6	-2.4	-0.4	-1.4	-1.8	-0.9	-2.4	-0.2	-0.9	-1.9
Qualifications: NVQ or HND or HNC or equivalent	1.1	1.3	2.8	-1.1	-1.2	0.6	-1.5	-1.5	-0.7	-0.4	-1.7	-0.9	-1.3
Long-standing illness, disability or infirmity	1.1	1.7	5.7	-1.0	-1.6	-0.6	-1.1	-1.6	-1.1	0.2	-1.1	-2.4	-1.2
Ever had stillbirth, spontaneous miscarriage or termination	1.1	1.1	4.6	1.4	-0.0	-0.2	-0.8	0.1	1.4	-0.9	2.1	1.1	0.5
Number of self-reported non-cancer illnesses	1.1	2.0	7.9	1.5	1.1	-0.7	0.1	-0.9	0.9	2.8	0.4	-1.8	1.7
Financial situation satisfaction	1.1	1.3	4.2	-0.9	-0.8	-0.0	-0.7	-0.9	-1.2	-1.0	-1.9	-2.0	-0.6
Ever depressed for a whole week	1.1	1.3	5.4	-1.0	-0.3	-0.7	0.2	0.0	-1.6	-1.0	-1.5	-2.3	-0.6
Deep venous thrombosis (DVT) (self-reported)	1.1	1.4	4.6	-1.1	-0.1	0.6	1.7	1.4	-1.1	1.0	0.3	2.2	-0.8
Blood White Count	1.0	7.6	18.1	1.8	3.4	2.4	3.5	3.0	0.7	4.2	-0.6	2.5	2.9
Eye problems/disorders: Diabetes related eye disease	1.0	1.1	3.4	-0.8	0.1	1.8	-0.5	0.0	-1.8	-0.7	-1.0	-1.1	-0.5
Severe depression (siblings)	1.0	1.2	5.1	-0.9	-0.5	-2.3	-0.3	0.5	-1.0	-0.6	-1.8	-0.6	-0.4
Fed-up feelings	1.0	1.8	4.8	-1.2	-1.3	-1.4	-0.8	-2.2	-0.5	-1.6	-0.4	-1.8	-1.0
Medication: Atenolol	1.0	1.3	3.6	-1.2	-1.2	0.1	-1.0	-1.9	-1.2	-0.2	-0.2	-1.5	-1.4
Hair/balding pattern: Pattern 2	1.0	1.3	6.2	1.7	0.5	-1.1	-0.4	-0.7	2.5	-0.1	-0.1	-0.8	1.0
Financial difficulties in last 2 years	1.0	1.4	7.2	-1.4	-0.5	0.1	0.4	-0.5	-1.4	0.1	-2.7	-1.2	-0.6
Medication: Ramipril	1.0	1.2	2.8	-0.6	-1.3	0.3	-1.1	-1.6	-1.0	1.5	0.6	-0.3	-1.7
Hair/balding pattern: Pattern 3	1.0	1.4	4.7	-1.3	-0.8	1.8	-1.3	-0.3	-2.2	-0.2	-0.3	0.0	-1.5
Illnesses of mother	1.0	1.3	5.8	-0.6	-0.3	0.6	0.6	1.4	-1.0	-2.4	-0.9	0.9	-1.0
Breastfed as a baby	1.0	1.2	2.5	0.8	1.3	-0.8	1.6	1.3	0.3	1.0	-1.4	0.8	1.3
Blood clot in the leg (DVT)	1.0	1.3	5.0	-0.9	0.1	0.5	1.6	1.3	-0.8	1.2	0.3	2.2	-0.5
Number of full brothers	1.0	1.2	5.6	-0.8	-0.1	0.7	0.9	0.0	-1.0	-1.1	-1.7	-2.4	-0.3
Qualifications: College or University degree	1.0	3.1	8.0	1.5	1.9	1.1	1.5	1.5	1.9	2.8	0.4	1.8	2.0
Pulse rate, automated reading	1.0	3.3	6.7	2.3	2.6	0.0	2.4	2.4	1.3	0.1	-0.0	1.0	2.5
Number of full sisters	1.0	1.2	4.3	-0.6	-0.9	-2.1	-1.7	-0.5	-0.3	-1.6	-0.4	-0.8	-0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.0	1.1	4.7	0.1	-0.6	-0.4	-2.2	-1.9	1.1	0.1	0.5	-1.1	-0.1
Medication: Gliclazide	1.0	1.1	3.6	-0.3	0.0	1.7	-0.9	-1.5	-0.0	1.2	-0.2	-1.9	-0.2
Medication: Atorvastatin	1.0	1.3	4.7	0.5	0.1	0.5	-0.4	0.5	1.2	1.6	1.8	2.2	0.3
Age started oral contraceptive pill	1.0	1.3	3.2	0.7	1.1	0.2	1.2	1.4	1.0	1.8	0.9	1.3	1.1
Alzheimer’s Disease (in mother)	0.9	1.0	5.6	0.5	-0.5	-0.3	-1.0	-0.1	0.5	0.2	2.4	1.6	0.1
Major Depression (MDD)	0.9	1.1	6.6	0.4	0.2	0.5	0.7	-0.3	1.1	1.2	2.6	0.3	0.5
Ovarian Cancer	0.9	1.1	3.6	0.7	1.1	0.3	0.3	0.9	1.1	1.9	1.5	0.9	1.0
LDL Cholesterol	0.9	1.5	2.9	1.0	1.6	1.6	1.7	1.3	0.4	1.0	-0.5	0.8	1.4
Smoking Status	0.9	2.1	5.2	-1.0	-1.4	1.3	-1.6	-1.9	-1.7	-0.7	-1.0	-2.3	-1.0
Cardiovascular Disease	0.9	3.0	9.5	-0.9	-1.3	2.0	-0.8	-3.1	-1.5	0.9	-0.1	-2.9	-1.3
Taking other prescription medications	0.9	1.4	3.5	-0.9	-0.7	-1.4	-1.1	-1.5	-1.5	1.1	-0.3	-1.9	-0.6
Number of incorrect matches in round	0.9	1.4	7.8	-0.2	1.0	0.4	0.9	1.3	-1.3	0.7	-0.1	2.8	0.7
Had other major operations	0.9	1.1	2.1	-1.2	-1.2	-1.2	-0.8	-1.0	-0.9	0.3	-1.4	-0.9	-1.2
Heel bone mineral density (BMD) T-score, automated (right)	0.9	2.1	5.6	-1.9	-2.1	-0.0	-0.6	-1.1	-1.2	-2.4	0.5	0.1	-1.9
Fluid intelligence score	0.9	1.9	4.3	1.2	0.8	1.0	1.5	2.1	1.6	-0.8	1.4	2.1	0.7
Father’s age at death	0.9	1.2	4.3	0.2	1.0	0.7	1.7	2.1	-0.2	0.7	-0.2	1.5	0.8
Frequency of tiredness / lethargy in last 2 weeks	0.9	1.4	5.2	1.2	1.6	1.6	0.8	-0.0	0.3	2.3	0.4	-0.0	1.3
Forced expiratory volume in 1-second (FEV1)	0.9	3.0	8.8	-1.9	-3.0	-1.1	-2.0	-1.6	-1.2	-1.3	0.1	-0.5	-2.5
Pulse rate	0.9	1.6	3.7	1.7	1.9	1.5	1.4	1.3	0.3	0.8	-0.3	0.1	1.6
Pulse wave peak to peak time	0.9	1.0	2.2	1.3	0.9	1.1	1.2	1.2	0.7	0.4	0.4	1.5	1.0
Emphysema/chronic bronchitis	0.9	1.0	2.9	-0.8	-0.9	-0.3	-0.6	-1.6	-0.2	1.4	0.6	-1.7	-0.4
Medication: Allopurinol	0.9	1.2	3.4	-1.8	-0.9	0.8	0.3	-0.4	-1.8	1.3	0.2	0.2	-1.5
Medication: Seretide 50 evohaler	0.9	1.1	3.5	0.4	1.0	0.4	1.2	1.2	0.6	1.0	1.1	1.9	0.7
Suffer from ‘nerves’	0.9	1.4	4.3	2.1	1.1	-0.5	0.6	-0.1	1.8	-0.3	-0.5	-0.7	2.1
Age at last live birth	0.9	1.3	7.5	-0.1	0.7	0.0	0.4	1.4	0.4	-0.1	-2.7	1.4	0.6
Family relationship satisfaction	0.9	1.2	3.3	1.4	1.1	0.4	1.5	0.8	1.0	0.3	-0.2	-0.9	1.8
Miserableness	0.9	1.5	5.1	-1.0	-1.0	-1.2	-0.9	-1.2	-1.1	-1.1	-1.0	-2.3	-0.9
Medication: Blood pressure	0.9	1.7	6.4	0.8	0.5	2.3	-0.6	-0.9	-0.7	1.6	2.5	0.2	0.5
Pain type(s) experienced in last month: Hip pain	0.9	1.2	4.7	0.2	-1.0	0.1	-1.3	-2.2	0.9	-1.5	-0.2	-0.9	-0.5
Systolic Blood Pressure	0.8	4.1	13.2	1.5	1.3	2.9	1.1	-1.1	0.3	3.6	3.3	0.7	1.4
Neuroticism	0.8	2.0	5.3	1.9	1.3	-2.2	0.4	0.3	1.7	-0.6	1.3	0.1	2.3
Trunk fat percentage	0.8	3.0	6.5	-2.1	-1.8	1.4	-1.5	-2.0	-2.5	0.3	1.0	-0.8	-2.5
Diverticular disease/diverticulitis (self-reported)	0.8	1.0	3.6	1.0	-0.3	1.1	-0.7	-1.9	1.1	-0.1	0.2	-1.3	0.7
Allergy	0.8	1.8	4.3	-0.4	-1.0	1.4	-1.4	-1.7	-0.6	-1.9	-0.7	-2.1	-1.1
Neuroticism score	0.8	1.6	4.9	1.6	1.6	-1.5	1.2	0.8	1.1	-0.6	0.4	0.3	2.2
Time employed in main current job	0.8	0.9	3.5	-1.6	-0.8	-0.2	-0.3	-0.3	-1.9	0.1	-0.3	0.6	-1.1
Falls in the last year	0.8	1.0	6.5	0.2	-0.2	-0.5	-0.9	-0.7	0.0	1.5	2.6	-0.2	0.2
Medication: Paracetamol	0.8	1.3	3.0	-1.4	-0.8	-1.3	-0.3	-1.0	-1.7	-0.5	-1.5	-1.1	-1.2
Shortness of breath walking on level ground	0.8	1.0	1.8	-1.3	-0.4	0.9	0.4	-0.3	-1.4	-1.1	-1.1	-1.2	-1.0
Loneliness, isolation	0.8	1.2	3.1	-1.2	-0.3	-1.2	-0.4	-0.9	-1.3	-0.5	-1.5	-1.8	-0.6
Alcohol drinker status: Never	0.8	0.9	2.2	0.8	0.3	-0.9	-0.7	-0.7	1.1	1.5	1.1	-0.7	1.3
Myopia	0.8	1.1	2.6	1.6	0.3	0.5	0.6	0.1	1.2	1.5	1.2	0.7	1.6
Intelligence (Savage-Jansen 2018)	0.7	2.1	4.6	1.6	0.4	1.7	0.4	0.9	2.0	-2.1	1.3	1.7	1.0
Schizophrenia (2014)	0.7	1.5	2.9	1.4	1.6	-0.3	1.6	1.6	0.4	1.3	-0.3	0.6	1.7
Vitamin and mineral supplements	0.7	1.0	2.7	0.6	1.6	-1.2	1.6	1.1	0.0	0.1	-0.1	0.9	1.0
Relative age voice broke	0.7	1.1	5.3	0.3	0.3	-2.3	-0.2	0.6	-0.2	1.2	0.5	-1.5	0.7
Medication: Lansoprazole	0.7	0.8	2.7	-0.9	-0.8	-0.6	-0.2	-0.7	-1.3	0.2	0.1	-1.7	-1.0
Pulse wave reflection index	0.7	0.8	2.0	-1.4	-1.2	0.7	-0.7	-1.1	-0.0	-0.2	-0.4	-1.0	-1.1
Birth weight	0.7	1.5	7.9	-0.2	-1.0	0.2	0.2	-1.0	1.6	2.8	1.0	0.7	-0.8
Body fat percentage	0.7	2.6	5.2	-1.9	-1.6	1.4	-1.5	-1.9	-2.2	0.6	1.3	-0.8	-2.3
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.8	1.8	1.2	1.1	0.1	1.2	0.6	0.2	1.3	-0.0	0.9	1.0
Heart disease (mother)	0.7	0.9	3.5	-0.2	-0.5	-0.3	-0.6	-1.7	0.4	1.9	1.0	-0.6	-0.2
Qualifications: nursing, teaching	0.7	1.1	5.1	0.3	0.6	-0.7	1.2	1.2	0.4	0.4	-0.4	2.3	1.1
Depressed Affect (Nagel 2018)	0.6	1.4	4.9	-1.2	-1.0	-0.8	-0.7	-2.2	-0.6	-0.6	0.1	-1.9	-0.9
Schizophrenia (2018)	0.6	1.3	3.7	1.1	1.3	0.1	1.6	1.1	0.2	1.9	0.0	0.5	1.4
Irritable Bowel Disease (IBD)	0.6	1.4	4.3	-1.5	-0.7	1.6	-0.2	-0.7	-0.8	0.8	-2.1	-0.7	-1.5
Hypothyroidism (self reported)	0.6	1.3	3.5	0.8	1.5	-1.9	0.3	0.9	0.5	-1.7	1.1	0.1	1.3
Ever used hormone-replacement therapy (HRT)	0.6	0.7	1.7	-0.3	-0.5	-0.7	-1.3	-1.1	-0.7	0.9	1.3	-0.4	-0.4
Current tobacco smoking	0.6	1.0	2.6	-0.7	-0.7	1.2	-0.7	-1.6	-1.6	0.1	-0.4	-1.1	-0.8
Average weekly fortified wine intake	0.6	0.7	3.1	-0.5	0.4	0.2	1.1	1.8	-0.9	-0.8	-0.4	1.0	0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.8	2.4	0.9	1.4	0.1	0.1	-0.3	0.6	1.5	-0.7	-0.3	1.4
Tinnitus: Yes, but not now, but have in the past	0.6	0.6	2.8	-0.5	0.1	-1.7	-0.2	-0.4	-0.5	0.8	-0.8	-1.1	0.1
Qualifications: CSEs or equivalent	0.6	0.8	2.7	-0.7	-0.4	-0.6	0.1	0.1	-0.6	-1.6	-1.6	-0.9	-0.8
Trunk fat mass	0.6	2.8	6.1	-2.0	-1.5	1.9	-0.8	-1.4	-2.4	1.1	1.3	-0.6	-2.5
Ever unenthusiastic/disinterested for a whole week	0.6	0.7	3.4	-0.7	-0.3	-0.7	-0.6	-1.1	-0.7	0.2	-0.4	-1.8	-0.4
Qualifications: None of the above	0.6	1.2	2.7	-1.2	-1.1	0.1	-1.0	-1.4	-1.3	-1.1	0.3	-0.8	-1.6
Hayfever/allergic rhinitis (self-reported)	0.6	0.8	2.7	-0.9	-0.8	-0.4	0.9	-0.4	-0.5	-0.4	-1.6	-0.9	-1.0
Impedance of arm (right)	0.6	2.6	8.4	-1.1	-1.4	-1.4	-2.1	-1.2	-1.1	-2.9	-1.9	-1.0	-1.0
Medication: Cholesterol lowering	0.6	0.9	3.3	0.9	-0.3	-0.4	-0.8	-0.8	1.7	1.8	0.9	-0.2	0.3
Peak expiratory flow (PEF)	0.6	1.3	5.1	-0.1	-1.8	-0.5	-2.3	-1.4	0.9	-0.4	1.1	-0.4	-0.7
Gout (self-reported)	0.6	0.8	2.5	-1.0	-0.5	1.4	0.8	-0.5	-0.7	1.6	0.2	-0.4	-1.0
Medication: Amlodipine	0.6	0.9	3.7	0.6	0.7	1.3	0.4	-0.6	-0.1	1.9	0.8	-1.0	0.4
High blood pressure (siblings)	0.6	0.8	3.6	1.1	0.4	0.3	0.7	-0.4	0.4	1.9	1.2	-1.0	0.6
Leg fat percentage (right)	0.6	2.2	4.3	-1.2	-1.5	1.0	-1.7	-2.1	-1.0	0.8	2.0	-1.2	-1.8
Whole body fat mass	0.6	2.3	4.5	-1.5	-1.2	2.1	-0.7	-1.3	-1.9	1.4	1.6	-0.6	-2.0
Leg fat mass (right)	0.6	2.3	4.1	-1.4	-1.3	1.9	-1.0	-1.4	-1.6	1.3	1.8	-0.9	-2.0
Supplements: Vitamin C	0.6	0.8	3.7	-0.5	-0.1	0.6	0.7	1.3	-1.0	-0.3	0.1	1.9	-0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.6	0.7	1.5	1.0	0.3	-1.0	0.6	-0.8	1.2	0.4	-0.1	-1.0	0.9
Back pain experienced in last month	0.6	0.8	5.3	0.8	-0.1	-1.1	0.6	0.7	0.3	-2.3	0.1	-0.0	0.4
Vascular/heart problems diagnosed by doctor	0.6	1.6	4.9	-0.4	-0.1	-1.4	0.4	1.8	1.1	-2.2	-1.4	1.6	-0.1
Basal cell carcinoma (self-reported)	0.6	0.7	3.0	-0.8	0.3	-0.2	1.2	0.7	-1.7	0.1	-1.1	0.5	-0.3
Neuroticism (Nagel 2018)	0.5	1.1	3.3	1.3	1.2	-1.7	0.7	-0.2	0.8	-0.0	0.1	-0.4	1.8
Alzheimer’s Disease (including proxy)	0.5	0.7	3.7	0.1	-0.3	0.4	-0.0	-0.0	0.6	0.9	1.9	1.3	-0.0
Breast Cancer	0.5	1.3	3.1	-1.7	0.4	0.0	1.3	1.5	-1.8	-0.7	-1.0	0.8	-0.8
Crohns Disease (2012)	0.5	0.8	1.8	-0.9	-1.3	0.7	-0.6	-1.0	0.2	0.9	-0.1	-1.0	-1.3
Neuroticism (2016)	0.5	0.8	2.5	1.0	0.9	-1.6	0.8	0.8	0.2	0.4	-0.2	0.0	1.4
Rheumatoid Arthritis	0.5	0.6	2.6	0.4	0.1	-1.2	-1.6	-0.7	0.8	0.1	0.6	-0.1	0.8
Lung FVC	0.5	2.5	5.6	-2.0	-2.2	-2.4	-0.5	-1.3	-1.6	0.5	-0.8	-0.8	-2.2
Ever had hysterectomy (womb removed)	0.5	0.6	2.1	-0.5	-0.5	-0.1	-1.5	-1.3	-0.4	0.4	1.0	-0.1	-0.6
Townsend deprivation index at recruitment	0.5	0.7	2.4	-0.7	-0.2	0.3	-0.8	-0.9	-1.2	-0.6	0.5	-1.5	-0.5
Age when periods started (menarche)	0.5	1.2	4.1	-0.4	-0.7	-2.0	-1.0	-0.9	0.5	1.3	-0.8	-1.8	0.1
High blood pressure	0.5	1.3	5.1	0.3	0.4	1.2	-0.0	-1.4	-1.2	2.3	1.0	-1.3	0.3
Stomach or abdominal pain in last month	0.5	0.7	1.9	0.8	1.4	-0.5	1.3	0.9	0.1	0.2	-0.5	0.4	1.0
Medication: Levothyroxine sodium	0.5	0.8	4.3	-0.2	1.3	-2.1	0.4	0.6	-0.7	-0.6	-0.0	-0.5	0.8
Hearing difficulty/problems with background noise	0.5	0.7	3.0	0.6	0.6	-0.5	0.2	-0.1	0.4	1.7	-1.2	-0.9	0.9
Forced vital capacity (FVC)	0.5	2.0	5.7	-2.0	-2.2	-0.3	-1.1	-1.0	-1.6	0.5	0.0	-0.3	-2.4
Illnesses of siblings	0.5	0.7	3.3	-0.3	-0.4	-1.0	-0.5	0.2	0.4	-1.8	-1.1	0.7	-0.1
Weight	0.5	2.3	5.7	-1.3	-1.2	2.4	-0.4	-1.0	-1.5	1.7	1.9	-0.3	-2.1
Hip circumference	0.5	2.2	5.6	-1.5	-1.9	1.2	-1.1	-1.1	-2.0	-0.6	1.4	-1.0	-2.4
Number of live births	0.5	0.7	3.9	-0.8	-0.1	-0.8	0.7	0.3	-0.6	-2.0	-0.5	0.5	-0.0
Depression (self-reported)	0.5	0.6	1.6	-0.5	-0.8	-0.7	-0.8	-1.3	-0.4	-0.6	-0.3	-1.1	-0.5
Pulse wave Arterial Stiffness index	0.5	0.6	1.2	-1.1	-0.6	-1.1	-1.0	-0.8	-0.5	-0.1	-0.2	-1.1	-0.7
Hypothyroidism/myxoedema (self-reported)	0.5	1.0	6.1	0.1	1.1	-2.5	-0.4	0.5	-0.4	-0.9	0.6	0.2	0.8
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.7	2.8	0.5	-0.2	-1.7	-1.1	-0.2	0.6	-0.5	0.1	-1.2	0.3
Neck or shoulder pain in last month	0.5	0.8	3.1	0.4	0.9	-0.3	1.7	1.0	0.2	1.2	-0.6	0.1	0.9
Medication: Blood pressure	0.5	0.9	5.7	0.9	0.3	-0.3	0.4	-0.7	0.6	2.4	0.6	-0.7	0.2
Mean time to correctly identify matches	0.5	1.0	4.8	-0.1	0.4	-2.2	0.0	0.6	-0.3	-1.3	-1.4	0.3	0.8
Arm predicted mass (right)	0.5	2.4	10.0	-0.6	-0.0	3.2	1.6	0.9	-0.9	2.5	1.4	0.6	-1.1
Overall health rating	0.5	1.0	3.3	-0.6	-0.3	0.8	-0.1	-1.8	-1.1	1.1	-0.4	-1.6	-0.3
Chest pain or discomfort	0.5	0.7	1.8	0.8	1.1	0.6	0.1	0.8	0.8	1.0	0.4	-0.1	1.3
Hypertension (Self-reported)	0.5	1.4	5.6	0.4	0.2	1.0	0.0	-1.6	-1.0	2.4	1.0	-1.7	0.2
Osteoporosis (self-reported)	0.5	0.6	1.5	0.8	0.9	-1.2	-0.6	-0.2	0.5	0.8	0.6	0.2	1.2
Illnesses of father: None of the above (group 1)	0.5	0.7	2.0	0.6	0.9	0.1	-0.3	1.4	0.8	-0.9	0.4	1.3	0.2
Tinnitus: Yes, now most or all of the time	0.5	0.6	2.5	0.6	-0.4	-0.7	-0.2	-0.4	1.1	0.6	-1.6	-1.0	0.2
Risk taking	0.5	0.8	3.0	-0.8	-0.7	1.2	0.3	0.2	-1.0	-0.5	1.7	0.2	-0.8
Unable to work because of sickness or disability	0.5	0.6	3.3	0.7	0.3	1.8	0.3	-0.5	0.4	1.0	0.7	-0.4	0.3
Supplements: Calcium	0.5	0.5	1.2	0.9	0.8	-0.3	-0.0	1.1	0.4	0.8	-0.7	0.3	1.0
Leg fat mass (left)	0.5	1.9	4.3	-1.2	-1.0	2.1	-0.4	-1.0	-1.5	1.6	1.7	-0.6	-1.8
Alzheimer’s Disease (in father)	0.4	0.4	1.5	-0.5	-0.4	1.2	-0.1	-0.6	-0.1	1.1	0.7	-0.1	-0.5
Prostate Cancer	0.4	0.5	2.0	0.6	-0.1	0.7	0.3	-0.1	1.3	1.4	-0.2	0.7	0.2
Bipolar Disorder (2011)	0.4	0.4	1.6	0.8	0.5	0.8	0.9	1.2	0.2	0.3	-0.2	-0.3	0.6
Body Mass Index (BMI) (2010)	0.4	0.5	1.7	-1.3	-0.6	0.2	0.2	0.0	-1.2	0.4	0.5	0.4	-1.1
Coronary Artery Disease (CAD)	0.4	0.5	1.2	0.3	-0.1	1.0	-0.2	-0.7	-0.2	1.1	0.9	-1.0	0.2
BMI	0.4	2.3	3.8	-1.5	-1.3	1.9	-0.9	-1.3	-1.8	2.0	1.3	-0.7	-1.9
Allergy or Eczema	0.4	1.0	3.0	-0.4	0.5	-1.3	0.5	1.7	-0.3	0.8	-0.9	1.7	0.4
Angina	0.4	0.5	2.2	0.2	-0.2	-0.7	-1.5	-0.9	0.2	0.1	0.8	-0.9	-0.1
Medication for hormone replacement therapy	0.4	0.5	1.6	0.4	0.3	-1.3	0.2	0.1	-0.3	-0.5	-1.2	-0.9	0.7
Supplements: Zinc	0.4	0.4	1.3	-0.9	-0.9	-0.7	0.0	0.1	-0.2	-0.2	-0.3	0.5	-1.1
Impedance of leg (right)	0.4	2.1	6.3	-0.8	-1.4	-1.9	-2.1	-1.4	-0.5	-2.5	-0.1	-0.7	-1.1
Leg fat-free mass (left)	0.4	1.9	6.8	-1.4	-0.9	2.6	0.3	-0.3	-1.7	1.7	0.6	-0.3	-1.8
Hand grip strength (right)	0.4	1.0	6.4	0.9	0.4	0.7	0.9	0.2	0.6	2.5	0.0	-0.6	0.3
Serious illness, injury or assault to yourself	0.4	0.4	3.5	-0.5	-0.2	-1.9	0.5	-0.0	-0.5	-0.3	0.0	-0.1	-0.2
Hayfever, allergic rhinitis or eczema	0.4	0.8	3.8	-0.3	0.4	-0.8	0.7	1.4	0.2	0.7	-0.3	2.0	0.3
Supplements: Glucosamine	0.4	0.5	2.6	0.2	0.1	-1.6	0.2	0.6	0.6	0.1	-0.8	0.6	0.6
Sitting height	0.4	2.7	8.5	-2.2	-2.3	0.8	-1.4	-1.8	-1.1	0.6	-0.0	-1.1	-2.9
Leg predicted mass (left)	0.4	1.9	6.7	-1.4	-0.9	2.6	0.3	-0.3	-1.6	1.7	0.6	-0.3	-1.8
Waist circumference	0.4	1.6	6.1	-0.6	-0.4	2.5	0.9	-0.6	-0.7	1.6	2.1	-0.3	-1.0
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.7	2.1	1.0	0.6	1.4	0.1	-0.7	0.5	0.5	1.0	0.9	0.8
Arm fat percentage (right)	0.4	1.5	2.8	-0.9	-1.0	1.7	-1.3	-1.6	-1.0	0.6	1.5	-0.9	-1.4
Alcohol intake versus 10 years previously	0.4	0.5	1.7	0.2	0.1	1.3	1.2	0.9	-0.5	-0.7	0.7	-0.3	-0.3
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	1.2	-1.0	-0.3	-1.1	-0.3	-0.7	-1.1	-0.4	-0.1	-1.0	-0.5
Impedance of arm (left)	0.4	1.7	6.1	-1.1	-0.9	-1.2	-1.6	-0.7	-1.6	-2.5	-1.2	-0.2	-0.8
Arm fat mass (right)	0.4	1.8	5.7	-0.9	-0.9	2.4	-0.5	-1.1	-1.1	1.4	2.0	-0.6	-1.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.6	4.3	0.2	0.2	-2.1	-0.4	-0.5	-0.1	0.2	0.9	-0.5	0.3
Headache pain in last month	0.4	0.7	2.5	-0.4	0.5	-1.2	1.6	0.7	-1.2	-0.7	-0.2	-0.1	-0.1
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	4.3	-0.8	-0.3	0.3	-0.3	0.5	-1.1	-2.1	-0.2	0.8	-0.3
Forced vital capacity (FVC), Best measure	0.4	1.6	4.8	-1.6	-1.9	-0.1	-1.2	-1.2	-1.2	0.2	-0.4	-0.7	-2.2
Arm fat-free mass (right)	0.4	2.0	7.4	-0.8	-0.4	2.7	1.3	0.7	-1.0	2.2	1.4	0.4	-1.3
Comparative body size at age 10	0.4	1.2	7.5	0.2	0.5	1.0	1.0	0.9	-0.6	2.7	0.8	0.7	-0.5
Health satisfaction	0.4	0.5	1.0	-0.4	0.3	-1.0	-0.3	-0.7	-0.9	0.5	-1.0	-1.0	-0.3
Angina (self-reported)	0.4	0.6	2.8	-0.1	-0.4	-0.5	-1.7	-1.0	0.1	-0.1	1.0	-0.7	-0.3
Medication: Ibuprofen	0.4	0.5	1.5	-0.8	0.1	-0.6	-0.3	-1.0	-0.7	0.6	0.3	-1.2	-0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	2.3	0.7	-0.2	-0.5	-0.4	-1.1	0.6	-1.5	0.3	0.0	0.5
Alcohol intake frequency.	0.4	1.0	1.7	-1.1	-0.9	-0.6	-1.3	-1.3	-1.0	-1.2	-0.3	-0.5	-1.0
Knee pain experienced in last month	0.4	0.6	1.8	0.3	0.4	-1.3	1.3	1.2	-0.1	-0.1	-0.7	-0.1	0.4
Illnesses of father: Heart disease	0.4	0.6	1.4	-0.5	-1.2	1.2	0.1	-0.6	-0.2	-0.5	-1.1	0.2	-0.8
Illnesses of siblings: Diabetes	0.4	0.5	1.3	-0.9	-0.3	1.2	0.8	0.1	-0.8	0.2	-0.7	-0.4	-1.0
Mineral and other dietary supplements	0.4	0.6	1.7	-0.7	-0.3	1.3	0.3	-0.4	-1.0	-0.5	-0.6	-0.9	-0.9
Osteoarthritis (self-reported)	0.4	0.5	2.2	-0.1	0.1	-1.4	0.1	-0.3	0.4	1.5	-0.4	-0.3	0.5
Smoking status: Current	0.4	0.7	1.9	-0.3	-0.5	1.3	-0.5	-1.4	-1.3	0.2	0.2	-1.0	-0.4
Arm fat mass (left)	0.4	1.8	5.4	-0.7	-0.6	2.3	-0.3	-0.8	-1.0	1.7	2.3	-0.3	-1.3
Ever taken oral contraceptive pill	0.4	0.5	1.9	0.4	0.8	1.4	1.0	0.8	0.4	-0.0	0.1	0.3	0.4
Mother’s age at death	0.4	0.5	1.1	0.1	0.4	-0.3	0.4	0.9	0.8	1.0	-0.6	0.5	1.0
Supplements: Fish oil (including cod liver oil)	0.4	0.6	1.6	0.9	0.7	0.5	0.0	1.0	0.6	0.2	0.4	1.3	1.0
Leg fat percentage (left)	0.4	1.5	4.1	-0.8	-0.9	1.2	-1.0	-1.5	-0.8	1.3	2.0	-0.9	-1.3
Average weekly beer plus cider intake	0.4	0.5	1.2	0.9	0.9	0.4	1.1	1.1	0.3	0.2	-0.3	0.8	0.5
Impedance of whole body	0.4	2.2	8.4	-1.2	-1.3	-1.3	-1.8	-1.1	-1.3	-2.9	-1.1	-0.4	-1.1
Depression (Nagel 2018)	0.3	0.5	1.1	0.7	0.9	0.3	0.4	-0.8	0.7	1.0	0.1	-0.1	0.9
Verbal and Numeric Reasoning (VNR)	0.3	0.6	2.4	0.5	0.0	0.9	0.8	0.4	1.1	-1.6	0.7	0.6	0.0
Lupus	0.3	0.4	1.6	-0.1	-0.6	-0.4	-0.6	-0.7	-0.5	-1.3	1.0	0.4	-0.4
Triglycerides	0.3	0.4	1.4	0.7	0.6	0.3	0.3	-0.6	0.8	0.2	-0.4	-1.2	0.6
Ulcerative Colitis	0.3	0.5	1.6	-0.6	-0.1	0.7	-0.8	-0.2	-0.4	1.0	-1.3	0.4	-0.6
Blood Eosinophil Count	0.3	2.3	10.9	1.2	1.5	-0.6	1.2	0.5	1.4	3.3	0.8	1.2	1.4
Blood Red Count	0.3	2.8	13.2	0.9	0.7	-3.6	2.1	1.5	1.9	-0.4	1.2	0.7	1.1
Hair Pigment	0.3	7.7	20.1	3.2	3.1	-1.6	2.2	1.0	3.6	4.5	1.9	0.5	3.5
Body mass index (BMI)	0.3	1.3	3.8	-0.6	-0.6	1.6	-0.4	-1.1	-0.8	1.5	1.9	-0.4	-1.1
Past tobacco smoking	0.3	0.5	2.5	-0.3	0.2	-0.1	1.4	0.8	-0.3	-0.1	0.3	1.6	-0.4
Trunk fat-free mass	0.3	1.6	6.2	-0.2	-0.2	2.5	1.2	0.7	-0.0	2.2	1.5	0.3	-0.9
Noisy workplace	0.3	0.3	1.5	-0.1	0.3	-1.2	0.0	-0.8	0.3	0.0	-1.0	-0.2	-0.1
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.3	0.9	-0.6	-0.6	-0.8	-1.0	-0.8	0.1	-0.2	-0.1	-0.1	-0.5
Trunk predicted mass	0.3	1.7	6.5	-0.1	-0.2	2.5	1.2	0.8	-0.0	2.2	1.6	0.3	-0.9
Length of working week for main job	0.3	0.3	0.7	0.7	0.8	-0.0	0.1	0.3	0.3	0.4	-0.7	-0.8	0.7
Loud music exposure frequency	0.3	0.4	1.7	-0.5	-0.5	0.8	0.0	-0.3	-1.3	-0.1	0.6	-0.6	-0.2
Qualifications: O levels/GCSEs or equivalent	0.3	0.4	1.6	-0.5	-0.0	-1.3	-0.2	-0.2	-0.4	1.2	0.6	0.6	-0.3
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	1.5	0.7	0.6	-1.2	0.1	0.2	0.1	-0.2	0.7	-0.7	0.6
Leg pain on walking	0.3	0.4	1.4	-0.1	-0.8	-0.4	-0.8	-0.9	0.2	0.1	0.2	0.1	-1.2
Smoking status: Previous	0.3	0.4	1.4	-0.3	-0.4	0.0	-1.1	-0.4	-0.1	-0.5	-0.9	-1.2	-0.1
Whole body fat-free mass	0.3	1.7	7.4	-0.7	-0.5	2.7	1.0	0.4	-0.8	2.1	1.2	0.1	-1.3
Leg fat-free mass (right)	0.3	1.7	6.9	-1.2	-0.6	2.6	0.8	0.1	-1.4	1.9	0.3	-0.1	-1.4
Arm fat percentage (left)	0.3	1.3	2.8	-0.9	-0.7	1.6	-1.0	-1.2	-1.3	0.9	1.7	-0.5	-1.3
Mood swings	0.3	0.5	1.3	0.5	0.4	0.3	1.2	-0.4	1.0	-0.7	1.1	-0.8	0.2
Friendships satisfaction	0.3	0.4	2.1	0.3	-0.0	0.6	-0.1	0.1	0.4	-0.4	-0.7	-1.4	0.5
Medication for cholesterol	0.3	0.5	1.9	-0.9	-0.3	-0.2	0.0	0.7	0.2	-0.1	-1.4	1.0	-0.6
Whole body water mass	0.3	1.8	7.8	-0.8	-0.5	2.8	1.0	0.4	-0.8	2.1	1.1	0.1	-1.4
Leg predicted mass (right)	0.3	1.7	7.3	-1.1	-0.5	2.7	0.8	0.1	-1.4	1.9	0.3	-0.1	-1.4
Average weekly champagne plus white wine intake	0.3	0.4	1.9	-0.1	0.2	-1.4	-1.1	0.3	0.1	-0.2	0.0	0.7	0.2
Hearing aid user	0.3	0.3	1.5	0.2	-0.1	0.7	-0.3	-0.6	0.9	-1.2	-0.5	0.3	-0.2
Medication: Paracetamol	0.3	0.4	1.7	-0.6	-0.3	-1.1	-0.1	-0.1	-1.3	-0.1	-0.2	-0.4	-0.5
Basal metabolic rate	0.3	1.9	8.0	-0.9	-0.7	2.8	0.7	-0.1	-1.0	2.0	1.4	-0.1	-1.6
Arm fat-free mass (left)	0.3	1.8	6.9	-0.7	-0.8	2.6	0.8	0.2	-0.6	1.8	1.7	-0.1	-1.6
Irritability	0.3	0.6	1.7	0.4	-0.2	-0.9	-0.1	-0.9	0.2	-1.3	-0.8	-1.1	0.4
Ever had prostate specific antigen (PSA) test	0.3	0.3	1.3	0.4	-0.2	-0.4	0.4	0.3	1.1	-0.3	-0.4	1.1	0.2
Diastolic blood pressure, automated reading	0.3	1.0	3.2	-0.2	-0.4	0.7	0.4	-1.8	-0.5	1.7	1.4	-1.0	-0.5
Cholesterol lowering medication	0.3	0.5	1.5	0.3	0.1	1.2	-0.7	-0.9	-0.1	0.6	1.0	-0.6	0.2
Pain experienced in last month	0.3	0.5	1.4	0.3	0.1	1.2	-1.0	-0.1	1.0	0.3	0.9	0.7	0.0
Arm predicted mass (left)	0.3	1.7	7.6	-0.7	-0.6	2.8	0.9	0.4	-0.5	1.9	1.5	-0.0	-1.4
Crohns Disease (2017)	0.2	0.4	1.2	-1.1	-0.6	0.8	0.3	-0.4	-0.1	0.7	-0.6	-0.1	-0.9
HDL Cholesterol	0.2	0.3	1.7	-0.2	-0.0	-0.0	-0.1	-0.1	-0.6	1.3	0.2	0.9	-0.4
Height	0.2	3.0	8.8	-1.9	-2.7	1.8	-1.3	-0.5	-2.1	-0.0	0.0	-0.7	-3.0
Hand grip strength (left)	0.2	0.5	1.8	0.1	-0.8	0.1	-0.2	-1.0	0.1	1.3	0.2	-0.9	-0.8
Average weekly spirits intake	0.2	0.2	1.1	-0.5	0.1	0.3	0.6	-0.0	-0.4	0.0	-1.0	-0.7	-0.3
Frequency of depressed mood in last 2 weeks	0.2	0.2	1.2	0.3	0.4	-0.5	1.1	0.0	0.4	-0.1	-0.3	0.1	0.5
Chronic bronchitis/emphysema (father)	0.2	0.3	1.1	-0.4	0.1	-0.3	-0.6	-0.7	-0.1	0.6	-0.1	-1.0	0.3
High blood pressure (mother)	0.2	0.3	1.2	-0.4	-0.2	-0.2	-0.4	-1.1	-0.3	0.4	-0.4	-0.8	-0.2
Impedance of leg (left)	0.2	1.0	3.8	-0.4	-0.8	-1.6	-1.2	-0.7	-0.3	-1.9	-0.5	-0.5	-0.5
Alcohol usually taken with meals	0.2	0.3	1.4	-0.4	-0.1	-0.7	0.2	1.2	0.0	-0.4	-0.3	0.6	0.3
Had menopause	0.2	0.2	1.0	-0.2	-0.5	0.0	-0.6	0.2	-0.5	0.5	1.0	0.3	-0.3
Standing height	0.2	1.7	4.8	-1.6	-1.2	2.2	0.2	0.5	-1.7	0.8	0.3	0.5	-2.1
Exposure to tobacco smoke at home	0.2	0.2	1.0	1.0	0.2	0.0	0.0	-0.1	0.5	-0.3	0.2	0.3	0.4
Wheeze or whistling in the chest in last year	0.2	0.4	1.6	0.2	1.3	-0.2	1.2	0.3	-0.2	0.5	-0.5	-0.4	0.6
Comparative height size at age 10	0.2	1.2	5.4	-0.7	-0.9	2.3	0.5	-0.1	-0.6	0.8	1.4	0.4	-1.6
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.4	1.4	0.0	-0.4	1.2	0.8	0.3	0.4	0.6	-0.2	0.6	-0.6
Average weekly red wine intake	0.2	0.3	0.7	-0.5	-0.5	0.0	-0.8	-0.5	0.5	0.7	0.4	-0.0	-0.5
High cholesterol (Self-reported)	0.2	0.4	0.9	-0.4	-0.7	0.2	-0.6	-0.7	0.1	0.9	0.7	-0.1	-0.8
Ever smoked	0.2	0.3	1.0	1.0	0.4	0.7	-0.5	0.1	0.6	-0.4	-0.2	-0.5	0.9
Fractured/broken bones in last 5 years	0.2	0.2	1.2	-0.6	0.5	-0.0	-0.0	-1.1	-0.3	0.5	0.2	-0.3	-0.2
Fasting Glucose	0.1	0.1	0.9	0.0	0.3	0.3	-0.2	-0.2	-0.4	0.9	-0.1	0.2	0.1
Mouth/teeth dental problems	0.1	0.2	0.7	0.1	-0.1	0.0	-0.2	-0.0	0.4	0.5	-0.4	0.9	0.4
Prospective memory result	0.1	0.2	0.4	0.0	-0.2	-0.6	0.1	-0.5	-0.6	0.7	-0.1	0.6	0.2
Illness, injury, bereavement, stress in last 2 years	0.1	0.2	0.5	-0.1	-0.4	0.1	-0.7	-0.2	-0.3	-0.7	0.5	-0.4	-0.2
Handedness (chirality/laterality): Left-handed	0.1	0.2	0.8	-0.5	-0.7	0.1	0.1	0.0	-0.4	-0.0	-0.1	-0.9	-0.1
Tanning	0.0	0.2	1.3	-0.4	-0.2	-1.1	-0.0	0.3	-0.0	-0.1	0.0	0.3	-0.2

Hub : Genes

GAS2L1

Models

Trait associations