TWAS hub - GCN1L1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Aorta	0.1260	0.0470	1.0e-03	0.004	NA	0.018	NA	0.000	1.8e-01	NA	3.4e-02	NA	3.1e-01
2	GTEx	Artery Tibial	0.1288	0.0421	6.2e-05	0.063	NA	0.051	NA	0.039	1.0e-05	NA	7.0e-05	NA	4.8e-04
3	GTEx	Esophagus Muscularis	0.1580	0.0470	2.7e-05	0.118	NA	0.092	NA	0.092	1.2e-07	NA	3.0e-06	NA	3.4e-06
4	GTEx	Nerve Tibial	0.1566	0.0477	7.7e-06	0.067	NA	0.095	NA	0.098	1.7e-05	NA	2.9e-07	NA	2.0e-07
5	GTEx	Ovary	0.2150	0.0760	1.6e-03	0.013	NA	0.014	NA	0.021	1.5e-01	NA	1.4e-01	NA	9.9e-02
6	GTEx	Skin Sun Exposed Lower leg	0.1320	0.0420	1.6e-04	0.031	NA	0.068	NA	0.054	1.3e-03	NA	2.8e-06	NA	2.6e-05
7	GTEx	Spleen	0.1890	0.0650	1.0e-03	-0.001	NA	0.003	NA	0.013	3.4e-01	NA	2.6e-01	NA	1.5e-01
8	METSIM	Adipose	0.0694	0.0219	2.1e-07	0.014	0.042	0.032	0.034	0.025	3.0e-03	5.1e-07	1.0e-05	5.9e-06	1.1e-04
9	YFS	Blood	0.1102	0.0223	0.0e+00	0.104	0.090	0.108	0.106	0.109	3.1e-32	8.6e-28	1.5e-33	8.0e-33	1.0e-33
10	TCGA	Prostate Adenocarcinoma	0.1083	0.0488	1.7e-05	0.023	0.045	0.042	NA	0.043	1.8e-03	1.7e-05	3.3e-05	NA	2.4e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Smoking Status	6.4	15.4	27.7	3.7	5.3	4.1	4.7	4.2	2.0	4.4	4.9	1.8	2.3
Comparative body size at age 10	6.0	16.6	26.1	5.1	4.1	3.8	4.0	3.4	4.9	4.4	4.7	1.5	3.6
Coronary Artery Disease (CAD)	5.2	6.2	16.6	-2.9	-3.0	-1.2	-3.0	-2.2	-2.1	-2.2	-4.1	0.2	-1.6
Current tobacco smoking	4.7	7.7	16.7	2.3	3.5	2.6	2.9	2.7	1.9	2.0	4.1	1.9	2.9
Smoking status: Current	4.6	7.3	16.7	2.0	3.2	2.3	2.9	2.7	1.8	2.3	4.1	1.9	3.0
Stomach or abdominal pain in last month	4.3	5.3	11.6	2.8	2.4	2.5	2.6	0.9	2.1	3.4	3.0	0.2	1.1
Shortness of breath walking on level ground	4.1	4.9	17.0	2.3	4.1	2.8	2.5	1.7	1.4	1.8	1.6	-1.3	0.2
Chest pain or discomfort	4.1	5.9	9.7	2.8	2.3	2.6	2.6	2.3	3.1	2.4	2.4	1.2	2.0
Birth weight	4.0	8.8	14.8	3.7	3.0	2.6	1.9	1.4	3.6	3.5	3.9	2.0	3.0
Intelligence (Savage-Jansen 2018)	3.9	12.0	22.9	4.0	3.5	3.0	3.7	4.8	3.0	1.9	4.3	2.7	2.7
Diastolic blood pressure, automated reading	3.8	11.7	19.7	-3.6	-3.6	-2.4	-2.5	-3.8	-3.8	-4.4	-4.4	-2.4	-2.3
Diabetes (mother)	3.7	4.7	11.8	2.0	3.4	2.7	3.0	2.3	0.6	1.3	2.3	0.3	1.5
Mean time to correctly identify matches	3.7	7.1	13.9	3.1	2.4	1.7	3.5	3.7	1.9	2.8	3.5	0.6	1.6
Reaction Time	3.5	6.6	14.2	3.1	2.8	2.0	3.8	3.7	1.0	2.4	3.0	-0.3	0.9
Heel bone mineral density (BMD) T-score, automated (left)	3.3	7.5	13.1	-2.7	-3.4	-3.0	-2.7	-2.9	-1.9	-3.6	-3.5	-1.3	-0.9
Diverticular disease/diverticulitis (self-reported)	3.2	3.7	7.3	2.6	1.1	2.7	2.0	1.2	2.6	1.9	1.2	1.4	1.7
Heel bone mineral density (BMD) T-score, automated (right)	3.2	7.4	15.2	-2.6	-3.2	-2.7	-2.5	-2.8	-2.3	-3.9	-3.4	-1.6	-0.9
Peak expiratory flow (PEF)	3.1	7.2	11.8	-2.4	-2.0	-2.7	-3.1	-3.3	-3.4	-3.1	-3.3	-1.0	-1.0
Eye problems/disorders: None of the above	3.1	3.6	7.5	1.2	0.4	1.2	1.7	1.4	2.0	2.7	2.6	2.3	2.1
Emphysema/chronic bronchitis	3.1	3.5	6.5	2.3	2.6	1.2	2.3	1.9	1.6	1.5	2.4	-0.1	1.4
Ever had bowel cancer screening	3.0	3.5	7.5	2.7	1.3	2.4	1.8	1.5	1.9	1.1	2.0	1.6	1.9
Number of self-reported non-cancer illnesses	3.0	5.2	13.8	3.7	3.1	3.0	2.8	1.9	1.5	1.5	2.0	-0.1	0.5
Alzheimer’s Disease (in father)	2.9	3.1	6.3	-2.2	-1.6	-2.5	-2.0	-1.5	-1.8	-1.9	-1.9	0.1	-1.1
Falls in the last year	2.9	3.9	6.9	2.2	2.2	2.0	2.3	1.9	1.4	2.4	2.6	0.8	0.9
Serious illness, injury or assault of a close relative in last 2 years	2.5	2.9	8.4	1.4	2.2	2.0	2.1	2.9	1.1	1.2	1.2	0.2	1.3
Ever depressed for a whole week	2.5	3.1	5.6	2.3	2.3	0.6	2.2	2.3	0.6	1.9	2.4	-0.5	-0.1
Body Mass Index (BMI) (2010)	2.4	3.2	6.8	-1.0	0.3	-2.3	-0.9	-0.6	-2.0	-2.6	-1.5	-2.6	-2.2
Heel T-Score	2.4	19.2	48.2	-4.8	-5.8	-3.5	-3.5	-2.5	-3.9	-6.9	-6.2	-0.2	-1.7
Number of treatments/medications taken	2.4	4.3	7.5	2.7	0.8	2.4	1.5	1.3	2.6	2.3	1.6	2.5	2.1
Pain type(s) experienced in last month: Hip pain	2.4	3.0	6.1	1.9	1.7	1.6	1.2	1.1	1.7	1.7	1.9	1.4	2.5
Type 2 Diabetes (T2D) (2012)	2.3	2.6	5.9	-0.8	-0.9	-1.7	-2.0	-0.9	-2.4	0.1	-1.8	-1.8	-2.2
Eye problems/disorders: Diabetes related eye disease	2.3	2.5	5.3	1.3	2.1	2.2	2.1	1.8	0.8	0.8	2.3	-0.1	0.3
Mouth/teeth dental problems: Bleeding gums	2.3	3.0	7.4	1.2	1.6	1.7	2.5	1.2	1.3	2.0	2.7	1.6	0.0
Ever smoked	2.3	4.1	8.4	2.6	2.8	2.0	2.5	2.9	-0.3	1.6	1.3	0.6	1.6
Osteoporosis (self-reported)	2.1	2.6	8.5	2.0	1.0	1.1	1.6	1.1	2.9	2.3	1.2	0.8	0.7
Taking other prescription medications	1.9	2.9	6.0	2.4	1.5	2.1	1.9	1.0	1.7	2.2	1.9	0.4	-0.1
Multivitamins +/- minerals	1.9	2.4	8.7	0.6	0.3	0.4	0.4	1.2	1.4	1.9	1.4	2.9	2.3
Gout (self-reported)	1.9	2.6	7.2	1.9	2.7	1.0	2.0	0.8	0.8	1.2	2.3	-1.6	0.4
Exposure to tobacco smoke outside home	1.9	2.6	4.4	1.2	1.9	1.3	2.1	2.0	1.6	1.9	1.8	0.5	0.7
Friendships satisfaction	1.9	2.3	5.8	-1.4	0.7	-2.1	-0.8	-0.2	-1.4	-1.4	-0.7	-2.3	-2.4
Systolic blood pressure, automated reading	1.8	5.2	14.6	-1.5	-1.7	-0.6	-1.1	-2.8	-2.0	-3.1	-3.8	-2.5	-1.6
Past tobacco smoking	1.8	3.3	7.7	-2.2	-2.8	-1.7	-2.1	-2.7	0.5	-2.0	-0.8	-0.1	-0.1
Crohns Disease (2017)	1.7	3.8	7.6	2.7	1.2	2.8	2.0	0.6	2.1	2.3	2.4	0.2	1.5
Systolic Blood Pressure	1.7	8.7	19.3	-2.6	-2.7	-0.7	-1.4	-3.6	-2.4	-3.9	-4.4	-3.2	-2.8
Other serious medical condition/disability diagnosed by doctor	1.7	2.2	4.5	1.7	2.1	1.6	1.8	1.6	1.1	0.6	1.0	1.3	1.4
Hearing difficulty/problems with background noise	1.7	2.7	7.0	1.8	2.0	1.4	1.9	1.7	1.4	1.1	2.6	-0.8	0.4
Alcohol drinker status: Previous	1.7	1.9	7.0	0.8	0.7	0.2	1.1	1.7	1.5	1.0	2.6	1.2	1.5
Pack years of smoking	1.7	2.5	4.9	1.2	1.7	2.1	2.2	1.8	1.8	0.1	1.3	0.6	1.7
HbA1C	1.6	1.8	4.3	1.8	0.7	2.1	1.2	1.5	0.6	0.8	1.4	1.7	0.5
Overall health rating	1.6	3.5	9.8	2.2	3.1	2.3	1.8	1.3	1.8	1.7	2.0	-0.0	0.3
Illness, injury, bereavement, stress in last 2 years	1.6	1.9	5.7	-0.9	-1.9	-1.5	-2.2	-2.4	-0.8	0.2	-1.0	0.2	-0.2
Eye problems/disorders: Cataract	1.6	1.8	6.6	0.1	1.3	-0.1	-0.9	-0.6	-0.7	-1.6	-1.7	-2.6	-1.7
Height	1.5	28.3	53.9	-2.5	-4.2	-6.2	-5.8	-7.1	-4.3	-3.0	-7.3	-5.4	-5.2
Pack years adult smoking proportion	1.5	2.3	4.5	1.0	1.9	2.0	2.1	1.8	1.7	-0.2	1.2	0.2	1.5
Comparative height size at age 10	1.5	8.0	19.9	-0.5	-1.4	-2.1	-2.3	-3.0	-3.1	-2.0	-4.5	-3.9	-3.2
Medication: Paracetamol	1.5	2.3	6.4	2.3	0.8	0.3	-0.1	-0.2	1.7	2.5	0.9	1.4	2.2
Depression (Nagel 2018)	1.4	2.1	8.0	1.7	1.6	0.9	0.7	0.6	0.4	2.8	1.6	-1.4	-1.3
Alzheimer’s Disease (including proxy)	1.4	2.0	5.3	-2.3	-1.0	-2.1	-1.7	-0.7	-1.3	-1.7	-1.1	0.1	-0.5
Primary Biliary Cirrhosis	1.4	2.0	3.6	1.4	0.9	1.4	1.3	1.3	0.8	1.9	1.9	1.8	1.1
Hearing difficulty/problems: Yes	1.4	2.1	6.9	1.5	2.6	1.9	1.7	1.8	0.8	0.4	1.0	-0.7	-0.2
Happiness	1.4	1.7	3.6	-1.9	0.2	-0.2	-0.3	1.2	-1.5	-1.9	-1.4	-0.8	-1.8
Wheeze or whistling in the chest in last year	1.4	2.5	6.7	1.8	2.6	2.1	1.7	1.9	0.4	1.0	1.3	1.0	0.7
Loneliness, isolation	1.4	2.0	6.4	-1.0	-0.7	-1.4	-1.6	-0.5	-2.5	0.1	-1.0	-1.5	-2.0
Eye problems/disorders: Glaucoma	1.4	1.6	3.5	-1.0	-1.2	-1.5	-1.9	-1.6	-0.7	-1.4	-1.3	0.7	0.9
Tinnitus: Yes, but not now, but have in the past	1.3	1.4	2.9	0.5	1.6	1.7	1.1	1.7	0.2	0.4	1.3	1.0	1.2
Number of live births	1.3	1.8	4.9	0.9	0.9	1.1	1.1	1.3	1.5	0.7	1.7	1.3	2.2
Qualifications: A levels/AS levels or equivalent	1.3	2.9	8.0	1.3	0.9	1.1	2.2	2.8	0.5	0.9	1.9	2.2	1.7
Medication: Cholesterol lowering	1.3	2.1	8.6	0.6	0.9	2.9	1.8	1.0	1.0	1.1	1.4	1.0	1.1
Ever highly irritable/argumentative for 2 days	1.3	1.6	6.2	0.6	2.0	1.0	1.8	2.5	-0.2	-0.6	0.7	-0.2	0.4
Headache pain in last month	1.3	2.2	4.4	2.1	1.2	1.2	0.6	0.6	0.2	1.8	2.1	2.0	1.6
Health satisfaction	1.3	1.7	4.8	0.8	2.2	1.1	1.1	1.4	0.9	1.9	1.5	0.4	0.2
High cholesterol (Self-reported)	1.3	2.3	10.3	1.2	1.2	3.2	1.6	1.1	1.0	0.9	0.3	1.2	1.7
Alcohol drinker status: Never	1.3	1.5	2.8	1.6	0.6	1.4	1.1	1.5	1.7	1.3	0.9	0.9	0.8
Commuting to job workplace: Cycle	1.3	1.6	3.4	-0.9	-0.3	-1.8	-1.0	-0.7	-1.8	-1.1	-1.3	-0.9	-1.8
Schizophrenia vs Biploar Disorder	1.2	1.6	6.0	0.1	-1.3	-1.6	-2.4	-2.0	0.2	0.3	-1.1	1.1	0.1
Respiratory disease	1.2	2.7	6.0	1.9	2.4	1.3	2.4	2.3	0.7	0.4	1.8	-0.4	-0.0
Bilateral oophorectomy (both ovaries removed)	1.2	1.4	2.4	-1.5	-1.4	-1.5	-0.5	-1.2	-0.8	-1.2	-0.8	-1.4	-1.0
Qualifications: CSEs or equivalent	1.2	1.6	3.6	-1.2	-0.8	-1.8	-1.3	-1.9	0.1	-1.8	-0.7	-1.1	0.6
Chronic bronchitis/emphysema (father)	1.2	1.5	3.0	0.0	-1.0	-1.2	-1.3	-1.5	-0.9	0.4	-1.2	-1.7	-1.7
Pain all over the body in last month	1.2	1.2	3.9	-0.9	-1.3	-0.6	-1.6	-0.9	-0.8	-0.5	-2.0	-0.1	-1.2
Medication: Simvastatin	1.2	1.7	5.1	0.7	0.9	1.9	2.3	1.6	0.8	-0.4	1.4	0.4	1.2
Hair/balding pattern: Pattern 3	1.2	1.8	3.2	0.7	1.5	1.4	1.7	1.5	1.5	-0.4	1.5	0.7	1.8
Hair/balding pattern: Pattern 4	1.2	2.8	6.6	0.8	0.0	2.0	1.9	2.2	1.7	0.7	0.7	2.6	2.1
Medication: Paracetamol	1.2	2.0	6.3	2.2	0.9	0.5	0.1	-0.2	1.3	2.5	0.8	1.4	2.0
Neck or shoulder pain in last month	1.2	1.7	4.4	2.0	2.1	1.9	1.4	1.0	0.2	1.3	0.8	0.1	0.6
Back pain experienced in last month	1.2	1.8	4.1	1.6	2.0	1.5	1.7	1.5	1.2	0.6	0.6	0.4	1.2
Mineral and other dietary supplements	1.2	1.6	5.3	-0.7	-1.2	-0.7	0.0	-1.3	-1.8	-0.5	-0.4	-2.3	-1.6
Hearing aid user	1.2	1.4	2.8	1.4	1.2	1.7	1.2	0.9	0.7	1.0	0.9	1.7	0.5
Risk taking	1.2	1.7	5.8	0.6	1.7	0.2	2.1	2.4	0.5	-0.9	0.8	-0.1	1.3
Alzheimer’s Disease (in mother)	1.1	1.3	4.3	-2.1	-1.1	-1.4	-1.4	-0.8	-0.7	-1.4	-0.7	0.1	0.6
Irritable Bowel Disease (IBD)	1.1	2.6	5.6	1.8	0.9	2.4	1.7	0.9	1.2	2.1	1.7	0.9	1.7
Bipolar Disorder (2011)	1.1	1.1	5.2	-1.1	0.3	-1.6	0.2	0.1	-0.9	-0.9	-0.0	-2.3	0.0
Blood Eosinophil Count	1.1	8.2	18.8	3.9	2.9	3.1	2.3	2.1	4.3	2.6	3.0	1.6	1.6
Lung FEV1/FVC ratio	1.1	5.8	12.7	-2.9	-2.3	-2.1	-3.6	-3.4	-2.5	-1.6	-2.4	-0.5	-1.0
Frequency of depressed mood in last 2 weeks	1.1	1.5	4.6	1.4	1.2	0.3	0.6	1.1	-0.3	2.1	2.0	-0.8	-0.9
Vitamin and mineral supplements	1.1	1.5	4.3	-0.7	-0.5	0.0	-0.6	-0.8	-1.3	-1.6	-1.4	-2.1	-1.6
Age when periods started (menarche)	1.1	2.7	7.2	1.0	1.9	1.2	1.6	1.8	2.7	1.0	2.0	1.0	1.4
Serious illness, injury or assault to yourself	1.1	1.3	4.2	1.2	1.6	2.0	1.6	0.8	0.7	0.2	0.6	-0.7	-0.4
Diabetes (self-reported)	1.1	1.6	3.6	0.2	1.7	0.9	1.4	0.8	-1.5	-1.0	1.4	-1.9	-1.1
Number of children fathered	1.1	1.2	3.5	1.1	-1.0	-0.1	-1.5	-1.8	-0.8	-0.3	-1.9	-0.1	0.7
Pulse wave peak to peak time	1.1	1.3	4.6	-1.4	-2.1	-0.4	-1.3	-1.8	-0.3	0.0	-0.8	0.4	-0.3
Mouth/teeth dental problems: Loose teeth	1.1	1.3	2.8	0.4	0.7	1.2	1.4	1.7	1.2	0.4	1.6	1.2	0.9
Commuting to job workplace: Car/motor vehicle	1.1	1.2	2.6	1.4	0.9	1.4	1.4	1.6	0.5	-0.1	-0.5	0.6	1.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.1	1.3	4.7	0.9	0.2	0.9	1.3	1.0	1.3	0.6	1.2	0.8	2.2
Myopia	1.1	1.7	3.7	0.4	0.8	0.8	1.3	1.9	1.5	1.9	1.5	1.2	0.6
Deep venous thrombosis (DVT) (self-reported)	1.1	1.5	5.3	0.8	0.3	0.7	0.9	0.4	2.3	1.4	0.7	1.7	1.5
Major Depression (MDD)	1.0	1.2	2.6	1.4	1.3	0.6	1.3	1.6	-0.8	1.0	1.2	-0.6	0.1
Sitting height	1.0	7.4	12.4	-1.2	-1.7	-3.3	-2.8	-3.4	-2.6	-3.3	-2.3	-3.5	-1.9
High blood pressure (siblings)	1.0	1.4	3.6	-1.4	-0.4	-1.0	-1.5	-1.9	-0.5	-1.1	-1.3	-1.1	-1.0
Number of full brothers	1.0	1.2	2.6	-1.0	-1.5	-1.4	-1.2	-1.6	0.1	-0.8	-0.2	1.1	0.9
Worry too long after embarrassment	1.0	1.7	5.9	0.8	0.6	-0.2	-0.1	-1.0	-2.1	-0.0	0.1	-2.2	-2.4
Seen a psychiatrist for nerves, anxiety, tension or depression	1.0	1.3	3.2	1.1	0.7	0.7	1.4	1.4	-0.4	1.8	1.4	-0.0	-1.1
Qualifications: College or University degree	1.0	3.1	6.7	1.9	2.0	1.6	2.3	2.6	-0.1	1.4	2.0	1.6	0.7
Pulse rate, automated reading	1.0	3.4	6.2	1.7	1.6	1.4	2.1	2.5	1.9	0.5	2.5	1.4	1.9
Age at last live birth	1.0	1.4	4.1	1.2	1.6	-0.2	0.9	1.5	0.3	0.3	1.6	0.3	2.0
Ever had stillbirth, spontaneous miscarriage or termination	1.0	1.1	2.6	-1.6	-1.6	-1.3	-1.0	-1.1	-0.8	0.4	-0.2	0.7	0.2
Verbal and Numeric Reasoning (VNR)	0.9	2.1	6.0	1.8	1.4	0.8	1.4	1.5	0.8	0.4	2.4	1.4	1.6
Mean Putamen Volume	0.9	1.0	5.8	0.6	0.4	0.6	-0.3	-1.4	0.9	2.4	0.7	0.6	-0.1
Fasting Glucose	0.9	1.1	2.7	0.2	1.4	1.0	0.9	1.6	-0.9	-0.1	-0.0	-1.3	-1.3
Supplements: Zinc	0.9	0.9	3.0	1.7	1.1	0.4	0.9	1.3	1.0	1.1	0.5	-0.1	0.2
Waist circumference	0.9	3.3	11.0	3.0	3.3	0.9	1.5	0.8	1.7	1.3	1.3	-1.8	0.2
Father’s age at death	0.9	1.2	3.1	-1.1	-0.4	-1.8	-0.8	-0.2	-1.7	-1.7	-1.1	-0.5	-0.3
Frequency of tiredness / lethargy in last 2 weeks	0.9	1.4	5.1	1.3	0.5	1.1	0.7	0.4	0.8	2.3	1.8	-0.6	-0.9
Pulse wave Arterial Stiffness index	0.9	1.1	4.0	1.4	2.0	0.1	1.1	1.6	0.1	-0.1	0.6	-0.7	0.0
Standing height	0.9	9.0	15.2	-0.7	-2.0	-3.7	-3.4	-3.9	-2.3	-1.4	-3.5	-3.9	-3.4
Breastfed as a baby	0.9	1.1	4.4	-0.2	-0.6	-0.1	0.7	1.6	-0.2	-0.4	0.3	2.1	1.6
Medication: Allopurinol	0.9	1.1	4.0	1.2	1.3	0.6	1.4	-0.3	0.5	0.7	2.0	-1.0	-0.1
Qualifications: NVQ or HND or HNC or equivalent	0.9	1.1	4.2	0.5	0.7	-0.8	-0.1	-0.9	0.7	1.2	0.4	-2.1	-1.6
Diabetes diagnosed by doctor	0.9	1.4	3.4	0.1	1.8	0.7	1.3	1.0	-1.4	-0.6	1.8	-1.2	-0.7
Qualifications: nursing, teaching	0.9	1.4	3.0	1.7	0.7	1.4	1.3	0.6	-0.1	1.1	0.2	1.7	1.7
Miserableness	0.9	1.6	5.5	1.7	1.2	0.9	1.2	0.9	0.1	1.6	2.3	-0.8	0.2
Leg fat percentage (left)	0.9	3.3	11.3	3.4	3.4	1.5	0.8	0.3	1.4	1.9	0.1	-1.4	0.3
Depressed Affect (Nagel 2018)	0.8	1.8	8.2	1.5	0.7	0.7	-0.1	-0.8	0.1	2.9	1.4	-1.3	-1.3
Neuroticism (Nagel 2018)	0.8	1.8	7.8	1.3	0.4	-0.2	-0.3	-1.1	0.0	2.8	1.0	-1.6	-1.8
Fed-up feelings	0.8	1.4	4.5	2.1	1.7	1.3	0.1	-0.2	-0.0	1.7	0.7	-0.8	-0.8
Neuroticism score	0.8	1.7	5.5	1.2	0.5	-0.7	-0.2	-0.4	-0.8	1.5	0.9	-2.3	-2.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.3	4.8	1.2	1.3	0.5	0.6	0.2	-1.3	0.8	-0.2	-1.4	-2.2
Medication for cholesterol, blood pressure or diabetes	0.8	1.3	7.4	-0.5	-0.5	-2.7	-1.3	-0.4	-0.5	-0.6	-0.9	-1.0	-0.8
Leg fat percentage (right)	0.8	2.8	10.8	2.9	3.3	1.2	0.7	0.0	0.9	1.5	-0.2	-1.9	0.0
Reason for reducing amount of alcohol drunk: Health precaution	0.8	0.9	2.9	-0.7	-1.5	-0.6	-0.9	-0.9	-0.3	-0.6	-1.7	0.9	-0.0
Medication: Seretide 50 evohaler	0.8	0.9	2.4	0.7	0.1	-1.1	-0.3	-1.2	0.8	0.8	1.2	-1.6	-0.4
Illnesses of siblings: Diabetes	0.8	1.0	2.8	0.2	1.7	1.0	1.7	0.7	-0.1	0.2	0.8	-1.4	-0.2
Supplements: Fish oil (including cod liver oil)	0.8	1.1	4.8	0.7	1.1	0.8	-0.3	0.9	1.4	-0.1	-0.4	2.2	0.9
Bipolar Disorder (2018)	0.7	1.2	5.0	-0.1	1.1	0.2	1.8	2.2	-0.8	-0.2	0.3	-1.1	0.4
BMI	0.7	4.2	17.5	2.9	4.2	0.7	1.4	1.0	0.1	0.2	1.2	-3.2	-0.8
Neuroticism	0.7	1.7	5.2	1.6	0.3	-0.5	-0.2	-0.7	0.4	2.3	1.3	-1.6	-2.0
Average weekly spirits intake	0.7	0.8	3.0	1.7	1.7	0.8	0.4	-0.5	0.6	-0.5	-0.4	-0.9	-0.0
Ever used hormone-replacement therapy (HRT)	0.7	1.0	3.3	-1.0	-1.4	0.1	-0.9	-0.9	0.5	0.7	-0.5	1.8	0.8
Medication for hormone replacement therapy	0.7	0.8	3.8	0.1	-0.1	0.2	-0.1	0.1	1.1	-0.0	0.6	1.6	2.0
Medication: Co-codamol	0.7	0.8	4.4	0.1	0.4	-0.1	-0.1	-0.3	0.0	2.1	0.1	-1.2	-1.2
Trunk fat percentage	0.7	2.8	8.0	2.8	2.8	1.0	0.3	-0.8	1.5	1.7	-0.6	-2.1	-0.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	1.0	3.9	0.7	0.5	0.1	-0.4	-0.5	0.0	2.0	1.1	-1.2	-1.5
Frequency of tenseness / restlessness in last 2 weeks	0.7	1.1	3.0	0.7	0.9	1.6	1.0	1.7	-0.4	1.4	1.2	-0.1	-0.4
Hair/balding pattern: Pattern 2	0.7	0.9	5.4	0.5	-0.2	0.4	-0.7	-1.0	0.8	2.3	0.4	1.1	0.3
Qualifications: None of the above	0.7	1.6	3.6	-1.5	-1.2	-0.4	-1.9	-1.5	-0.4	-1.1	-1.9	-0.3	-1.0
Illnesses of siblings	0.7	0.9	4.7	0.6	-1.2	0.3	-0.6	0.5	0.2	1.4	0.3	2.2	0.4
Hip circumference	0.7	2.9	11.8	3.4	2.2	0.5	1.1	-0.1	1.5	1.2	0.8	-2.6	-0.3
Tense / ‘highly strung’	0.7	1.2	5.1	-0.3	-0.5	-1.7	-0.3	-0.9	-0.9	0.2	-0.6	-1.4	-2.3
Blood clot in the leg (DVT)	0.7	0.9	3.5	0.3	-0.1	0.4	0.5	0.0	1.9	1.0	0.6	1.5	1.2
Body fat percentage	0.7	2.6	8.5	2.8	2.9	1.0	0.4	-0.6	1.3	1.5	-0.6	-2.1	-0.4
Family relationship satisfaction	0.7	0.8	2.8	-1.3	-0.1	-1.6	-0.4	0.3	-0.7	-0.3	-0.2	-0.5	-1.7
Knee pain experienced in last month	0.7	1.0	2.4	-0.3	-1.0	-0.4	-1.5	-1.5	-0.4	-0.8	-1.5	0.4	-1.1
Smoking status: Previous	0.7	1.1	1.8	1.1	1.3	0.6	0.8	1.0	-1.0	1.3	-0.6	-0.8	-1.4
Mood swings	0.7	1.3	2.5	1.0	1.2	0.7	1.0	0.7	0.1	1.3	1.4	-1.3	-1.6
Long-standing illness, disability or infirmity	0.7	1.0	3.6	1.1	1.9	1.2	0.9	0.6	-0.2	-0.4	0.2	-0.2	1.6
Medication: Gliclazide	0.7	0.8	3.0	-1.0	0.6	-0.8	-0.0	0.1	-1.7	-1.5	0.4	-0.8	-0.4
Average weekly champagne plus white wine intake	0.7	0.9	3.3	0.6	0.5	-0.5	1.0	0.9	0.2	-1.8	0.7	-1.6	0.4
Age at First Birth	0.6	0.9	2.8	-0.8	-0.6	-0.5	-0.9	-1.0	-1.7	-0.9	-1.0	-0.2	-1.2
HDL Cholesterol	0.6	1.1	2.7	0.4	1.2	1.1	1.4	0.8	0.3	1.6	1.5	-0.2	0.4
Blood Red Count	0.6	5.6	13.8	-0.1	-1.4	-3.4	-0.7	-2.9	-0.6	-3.1	-3.7	-3.0	-0.3
Waist Hip Ratio (WHR)	0.6	2.5	9.9	0.9	3.1	1.3	1.8	2.5	0.8	0.9	1.2	0.5	-0.4
Type 2 Diabetes (T2D) (2018)	0.6	1.1	2.8	-0.2	1.6	0.2	1.1	0.9	-1.4	-0.5	1.1	-1.7	-0.6
Severe depression (siblings)	0.6	0.6	3.3	-0.2	0.7	-1.0	-0.3	0.3	-0.3	-0.8	-0.7	-1.8	-0.4
Maternal smoking around birth	0.6	0.8	3.0	0.1	-0.5	-1.7	-0.5	-1.5	0.6	-0.6	0.4	-1.2	0.6
Body mass index (BMI)	0.6	2.7	10.1	2.7	3.2	0.9	1.5	0.6	0.8	0.6	0.9	-2.0	0.2
Trunk fat mass	0.6	2.7	8.0	2.7	2.6	0.3	0.1	-1.0	0.8	1.1	-0.7	-2.8	-0.9
Number of incorrect matches in round	0.6	1.1	3.2	-1.0	-1.8	-1.2	-1.0	-1.2	-0.3	1.0	-0.3	-0.4	-1.0
Ever unenthusiastic/disinterested for a whole week	0.6	0.8	2.1	-0.1	1.4	-0.7	0.5	1.4	-0.8	-0.1	0.2	-1.2	-0.8
Arm fat mass (right)	0.6	2.3	8.0	2.7	2.8	0.4	0.7	-0.4	1.2	0.9	0.4	-2.3	-0.1
Qualifications: O levels/GCSEs or equivalent	0.6	0.9	3.7	-0.1	-0.6	0.6	1.0	0.8	0.6	0.2	0.6	1.6	1.9
Glaucoma (self-reported)	0.6	0.7	1.4	-0.1	-0.7	-1.2	-1.2	-1.0	-0.7	-1.1	-0.5	0.6	0.5
Medication for pain relief, constipation, heartburn	0.6	1.0	3.2	-1.3	-0.4	-0.7	-0.3	0.6	-0.6	-1.8	-0.5	-1.4	-1.2
Medication: Omeprazole	0.6	0.7	3.4	0.3	0.5	0.7	0.2	-0.6	-0.3	1.9	-0.2	0.7	-1.2
Whole body fat mass	0.6	2.7	8.7	2.7	2.8	0.1	0.3	-0.8	0.7	0.9	-0.5	-3.0	-0.7
Leg fat mass (right)	0.6	2.4	8.7	2.5	2.9	0.0	0.3	-0.5	0.2	0.6	-0.4	-2.9	-0.6
Alcohol intake frequency.	0.6	1.4	5.0	0.6	-0.5	0.6	1.1	1.9	2.2	0.7	1.5	0.9	0.4
Leg pain on walking	0.6	0.8	3.3	1.2	1.8	0.5	0.7	0.3	0.2	-0.8	-0.6	-1.1	-0.2
Arm fat percentage (left)	0.6	2.3	8.4	2.5	2.9	0.9	1.0	-0.0	1.5	1.1	0.3	-1.9	-0.1
Handedness (chirality/laterality): Left-handed	0.6	0.8	4.8	0.1	-0.4	-0.0	0.8	0.3	0.0	2.2	1.1	0.6	-0.8
Arm fat mass (left)	0.6	2.6	8.9	2.7	3.0	0.5	0.7	-0.3	1.1	0.8	0.3	-2.5	-0.2
Unable to work because of sickness or disability	0.6	0.8	2.2	-1.3	0.4	-1.1	0.3	0.8	-0.9	-1.5	0.3	-0.9	0.5
Pain experienced in last month	0.6	1.0	2.9	-1.7	-0.9	-1.3	-0.1	0.9	-0.9	-1.3	-0.4	-0.7	-0.7
Heart disease (siblings)	0.6	0.7	1.7	1.1	1.3	1.0	1.1	-0.2	0.5	-0.6	0.0	-0.8	0.7
Leg fat mass (left)	0.6	2.4	8.3	2.7	2.9	0.3	0.4	-0.4	0.6	0.9	-0.1	-2.6	-0.3
Bipolar Disorder or Schizophrenia	0.5	1.2	3.8	-1.0	0.4	-1.3	1.3	1.6	-2.0	0.5	-0.0	-0.8	-0.0
Schizophrenia (2018)	0.5	1.0	3.7	-1.2	-0.5	-1.8	0.2	0.2	-1.9	0.8	-0.3	-0.2	-0.4
Worry (Nagel 2018)	0.5	1.1	6.1	0.9	-0.1	-0.5	-0.1	-0.7	0.5	2.5	1.0	-0.8	-1.4
Rheumatoid Arthritis	0.5	0.7	3.5	1.9	0.1	0.8	0.4	0.1	1.3	0.7	0.4	-0.2	0.5
Ulcerative Colitis	0.5	0.7	2.4	0.6	-0.0	0.5	0.5	1.2	0.3	1.4	0.2	0.8	1.5
Medication: Atenolol	0.5	0.6	3.2	0.3	0.1	1.2	1.0	-0.2	0.2	-0.3	0.5	0.3	1.8
Had other major operations	0.5	0.6	1.7	0.6	1.3	-1.1	-0.0	-0.8	-0.6	0.6	0.1	-1.0	-0.9
Mouth/teeth dental problems	0.5	0.7	1.7	-0.7	-1.3	-0.7	-0.7	-0.7	-0.8	-0.5	-0.9	-1.2	0.3
Heart attack	0.5	0.6	2.9	0.1	-1.6	0.7	0.3	0.2	0.4	-0.5	-0.0	0.1	1.7
Weight	0.5	2.5	12.3	2.2	2.1	-0.8	-0.2	-1.2	-0.3	-0.0	-0.7	-3.5	-1.2
Arm fat percentage (right)	0.5	2.1	6.8	2.4	2.6	0.9	0.9	-0.1	1.8	1.2	0.6	-1.5	-0.0
Time employed in main current job	0.5	0.5	2.8	0.4	-0.8	-0.7	-0.1	1.0	-0.2	-1.7	-0.6	0.3	0.2
Asthma	0.5	0.9	3.7	0.3	0.7	-0.4	0.8	0.5	-0.2	-0.9	0.5	-1.9	-1.6
Length of working week for main job	0.5	0.6	1.8	0.7	1.1	0.3	1.3	0.6	0.3	0.6	1.2	-0.5	0.0
Birth weight of first child	0.5	0.9	3.2	1.8	0.5	1.2	-0.1	-1.1	0.8	1.3	-0.1	0.3	0.3
Migraine (self-reported)	0.5	0.7	2.7	0.4	-0.2	-1.0	-0.9	-0.7	0.1	0.3	0.2	1.6	1.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.5	1.4	0.9	-0.9	-0.7	-1.2	-1.1	0.5	0.6	0.0	0.6	-0.2
Number of full sisters	0.5	0.6	1.3	0.5	1.1	-0.4	0.8	0.7	0.1	1.0	0.1	-1.0	-1.1
Suffer from ‘nerves’	0.5	0.9	3.0	-0.3	-0.4	-1.7	-1.1	-0.8	-1.2	1.0	0.4	-0.6	-0.9
Supplements: Vitamin C	0.5	0.6	1.2	1.1	0.7	-0.1	0.4	0.3	0.8	1.1	0.8	-0.6	-0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.6	1.9	0.3	0.6	1.4	1.2	0.9	-0.9	-0.3	-0.6	0.2	-0.3
Illnesses of father: Heart disease	0.5	0.8	2.0	-0.8	-0.4	-0.2	-1.0	-1.3	0.5	0.6	0.3	1.4	1.1
Mouth/teeth dental problems: Mouth ulcers	0.5	0.7	1.8	-0.1	-1.1	-1.1	-0.8	-0.5	-0.8	-0.1	-1.3	0.1	-1.4
Asthma (self-reported)	0.5	1.1	2.9	0.8	1.1	0.0	1.3	1.1	-0.0	-0.7	0.8	-1.7	-1.3
Wears glasses or contact lenses	0.5	0.6	3.0	0.7	-0.0	0.6	-0.2	1.7	0.8	0.7	-0.1	0.9	0.5
Commuting to job workplace: Public transport	0.5	0.5	3.0	-0.8	0.2	-0.5	-0.2	-0.4	0.6	0.6	1.7	0.7	-0.5
Medication: Atorvastatin	0.5	0.6	2.0	-1.0	-0.6	1.4	-0.5	-0.1	-1.3	-0.4	-0.7	0.1	0.1
Ever had prostate specific antigen (PSA) test	0.5	0.6	1.6	1.3	0.9	0.8	0.7	0.9	0.7	0.1	0.7	0.1	0.6
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	3.0	0.5	0.2	0.6	-0.0	-0.9	-0.2	1.7	-0.1	1.1	-0.9
Supplements: Calcium	0.5	0.5	2.9	-0.8	-0.2	0.1	0.4	1.7	0.8	-0.0	0.7	0.8	-0.0
Ulcerative Colitis (UC)	0.4	0.7	1.4	0.5	0.5	1.2	0.7	0.7	0.2	1.1	0.0	1.2	1.1
LDL Cholesterol	0.4	0.6	2.7	0.4	0.7	1.6	1.0	0.6	0.2	0.7	-0.6	0.2	0.1
Neuroticism (2016)	0.4	0.6	3.0	0.7	-0.5	-0.0	0.4	0.2	0.1	1.7	0.4	-0.8	-1.2
Lung FVC	0.4	2.0	5.2	-0.4	-0.3	-0.6	0.9	1.7	1.5	-0.1	2.3	2.0	2.1
Chronotype (morning person)	0.4	0.8	4.1	0.6	1.2	0.3	0.4	-0.9	0.3	0.8	2.0	0.4	0.8
Hand grip strength (left)	0.4	1.0	2.6	-0.8	-0.9	-0.5	-1.0	-1.2	-1.6	-1.6	-0.9	-0.3	0.4
Sensitivity / hurt feelings	0.4	0.7	2.1	1.2	-0.6	-0.7	0.1	-0.2	0.4	0.4	0.4	-1.3	-1.5
Relative age of first facial hair	0.4	0.8	2.6	-0.7	-1.0	-0.7	-0.5	-0.5	-1.6	-0.1	-0.6	-1.0	-1.3
Medication: Metformin	0.4	0.5	1.5	-0.0	1.2	0.7	0.8	0.5	-0.4	-0.6	1.0	-0.5	-0.7
Supplements: Glucosamine	0.4	0.5	2.8	-0.0	-0.2	0.0	-0.3	0.7	0.7	0.1	-0.1	1.7	1.0
Nervous feelings	0.4	0.7	2.2	0.3	-0.1	-0.7	-0.2	-0.2	1.0	1.5	0.9	-1.0	-1.3
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	1.6	1.3	0.2	0.6	-0.0	-0.6	0.4	0.6	1.0	-0.9	-0.3
Alcohol intake versus 10 years previously	0.4	0.6	1.6	-1.3	-0.3	-0.3	0.4	1.2	-0.4	-0.9	-0.6	-0.0	-1.1
Worrier / anxious feelings	0.4	0.8	1.9	1.4	-0.6	0.1	-0.0	-0.6	-0.3	1.2	0.8	-1.4	-1.3
Forced expiratory volume in 1-second (FEV1)	0.4	1.4	4.3	-0.7	-1.0	-2.1	-1.5	-1.2	-0.9	-1.0	-1.1	-0.8	-1.1
Mouth/teeth dental problems: Dentures	0.4	0.7	1.6	-0.6	-0.4	0.1	-1.2	-0.0	-1.3	-0.9	-1.2	-0.4	-0.9
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	1.6	1.0	1.0	-0.4	-0.1	-0.3	0.7	-0.2	0.2	0.6	1.3
Depression (self-reported)	0.4	0.5	2.3	0.2	-0.6	0.1	-0.1	0.2	-1.5	0.2	0.1	0.6	-1.5
Medication: Lansoprazole	0.4	0.4	1.3	0.4	-0.7	-0.2	0.0	-1.0	-1.2	-0.5	-1.0	-0.3	-0.3
Exposure to tobacco smoke at home	0.4	0.5	2.9	0.3	-0.1	0.2	0.0	-0.4	1.7	0.5	0.9	-0.5	0.2
Age at first live birth	0.4	0.8	2.1	1.3	1.3	0.5	0.9	1.4	-0.3	0.1	0.8	-0.2	0.6
Arm predicted mass (right)	0.4	2.2	10.5	1.5	1.5	-1.2	0.0	-0.8	-1.6	-0.9	-0.4	-3.2	-0.9
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.9	2.7	-0.4	-0.5	-0.8	-1.0	-0.6	-0.7	-0.4	-0.6	-1.6	-1.7
Medication for cholesterol	0.4	0.5	2.2	-0.0	0.6	-0.5	0.6	1.5	-0.6	0.8	1.0	-0.4	-0.5
Breast cancer (self-reported)	0.4	0.4	2.7	-0.1	0.1	-0.4	0.5	0.3	-0.3	0.1	0.2	-1.6	-1.1
Osteoarthritis (self-reported)	0.4	0.5	1.0	0.8	0.4	0.9	0.5	1.0	0.7	0.8	-0.3	0.8	0.6
Mother’s age at death	0.4	0.5	1.2	-0.3	0.0	-0.7	0.9	1.1	0.6	-0.5	1.0	0.5	0.2
Financial situation satisfaction	0.4	0.5	1.7	-0.3	0.6	-0.5	-0.2	0.1	-0.7	-0.7	-0.9	-0.9	-1.3
Medication: Bendroflumethiazide	0.4	0.5	1.9	-0.6	-0.5	0.4	0.1	-0.9	-0.1	-0.1	-1.4	-1.0	-0.9
Medication: Lisinopril	0.4	0.5	1.6	0.0	-0.8	1.1	-0.4	-0.7	-0.5	0.3	-0.8	-0.2	-1.3
Arm fat-free mass (left)	0.4	1.8	8.8	1.7	1.4	-1.1	-0.1	-0.9	-0.9	-0.7	-0.2	-3.0	-0.8
Fractured/broken bones in last 5 years	0.4	0.5	2.5	0.2	0.4	0.4	0.4	-0.5	-0.6	-0.2	0.7	1.6	1.0
Heart attack/myocardial infarction (self-reported)	0.4	0.6	2.3	0.2	-1.4	0.8	0.3	0.2	0.3	-0.7	-0.2	0.0	1.5
Crohns Disease (2012)	0.3	0.5	1.1	0.6	0.1	1.1	0.7	-0.1	0.7	0.6	0.8	-1.0	0.2
Schizophrenia (2014)	0.3	0.6	3.8	-0.3	-0.0	-2.0	-0.0	-0.3	-1.1	0.6	-0.1	-0.8	-0.1
Triglycerides	0.3	0.6	2.0	-0.7	-1.4	-0.5	-0.7	-0.4	-0.2	-0.2	-1.3	0.6	0.3
Hypothyroidism (self reported)	0.3	0.6	2.1	-0.5	-1.1	-0.3	-1.0	-0.9	0.3	-0.4	-0.5	-0.6	-1.5
Ever had hysterectomy (womb removed)	0.3	0.3	1.5	-1.2	-0.5	-0.4	-0.1	-0.2	-0.4	-0.8	-0.3	-0.2	-0.7
Diabetes (father)	0.3	0.4	1.9	0.0	0.2	0.5	0.8	0.6	0.3	0.5	1.4	0.4	0.7
Leg fat-free mass (left)	0.3	1.7	9.3	1.5	1.3	-1.2	0.2	-0.7	-0.2	-0.7	0.3	-3.0	-0.9
Hand grip strength (right)	0.3	0.8	3.5	-0.8	-0.6	-0.2	-0.2	-1.1	-1.2	-1.9	0.0	-0.7	0.2
Townsend deprivation index at recruitment	0.3	0.4	1.2	-0.6	1.1	-0.1	1.0	0.6	-0.4	-0.0	0.7	-0.3	-0.4
Relative age voice broke	0.3	0.5	2.2	-0.5	-1.1	-0.0	-0.3	-0.9	-0.1	-0.2	-0.6	1.5	-0.1
High blood pressure	0.3	0.9	1.8	-0.1	0.7	1.4	0.6	-1.2	-0.8	-0.7	-0.8	-1.2	-1.3
High blood pressure (mother)	0.3	0.4	1.5	0.8	0.5	1.1	1.2	0.6	-0.1	0.7	-0.0	-0.1	-0.4
Leg predicted mass (left)	0.3	1.5	8.5	1.5	1.2	-1.1	0.2	-0.6	-0.2	-0.6	0.4	-2.9	-0.9
Alcohol usually taken with meals	0.3	0.5	1.6	0.9	-0.3	0.0	0.5	1.3	1.2	0.4	-0.5	0.3	0.5
Had menopause	0.3	0.4	1.6	-0.3	0.1	0.3	-0.6	-0.6	1.3	0.8	-0.5	0.2	-0.4
Financial difficulties in last 2 years	0.3	0.4	1.2	0.3	1.1	-1.1	0.2	0.7	-0.6	-0.1	0.7	-0.2	0.2
Fluid intelligence score	0.3	0.6	2.2	1.1	0.7	-0.3	0.5	1.1	0.3	0.1	1.5	0.5	0.5
Impedance of arm (right)	0.3	1.6	4.1	-0.7	-1.3	-0.1	-1.5	-1.2	2.0	1.5	-1.0	1.6	-0.3
Trunk fat-free mass	0.3	1.6	7.1	1.2	0.6	-1.4	-0.2	-0.9	-1.5	-1.2	-0.2	-2.7	-0.8
Prospective memory result	0.3	0.3	1.1	-1.1	0.3	-0.2	-0.2	-0.8	0.2	0.1	-0.5	-0.8	-0.5
Lung cancer (father)	0.3	0.4	1.9	1.0	0.1	0.4	0.8	-0.2	0.2	0.2	-0.1	-1.4	0.3
Illnesses of mother	0.3	0.3	1.1	-0.5	-0.8	-0.1	-1.1	-0.8	-0.3	0.2	-0.2	0.3	-0.2
Trunk predicted mass	0.3	1.6	7.0	1.2	0.6	-1.5	-0.2	-0.9	-1.5	-1.2	-0.1	-2.6	-0.8
Pulse wave reflection index	0.3	0.4	1.8	0.9	0.6	-0.1	-0.1	0.2	0.4	0.3	0.7	0.4	1.3
Loud music exposure frequency	0.3	0.3	0.9	-0.7	0.4	-0.7	-0.1	0.1	-0.5	-0.4	0.5	-0.3	-0.9
Medication: Amlodipine	0.3	0.4	1.9	0.5	-0.1	0.5	-0.0	0.0	0.3	0.6	0.2	1.4	0.9
Chronic bronchitis/emphysema (mother)	0.3	0.3	0.8	0.8	0.6	-0.4	-0.0	0.9	0.6	0.5	-0.1	-0.7	-0.0
Arm fat-free mass (right)	0.3	1.8	9.0	1.7	1.4	-1.1	0.1	-0.9	-1.1	-0.7	-0.3	-3.0	-0.7
Medication: Blood pressure	0.3	0.5	3.1	0.2	0.6	1.8	1.1	0.0	-0.5	0.2	0.6	-0.1	0.2
Angina (self-reported)	0.3	0.4	1.9	0.3	0.0	0.4	0.4	0.4	0.1	-1.4	-0.5	0.4	1.1
Medication: Ibuprofen	0.3	0.4	1.5	0.7	0.7	-0.6	0.0	-0.2	0.3	-0.8	-0.1	0.7	1.2
Whole body fat-free mass	0.3	1.6	8.0	1.4	0.9	-1.3	0.0	-0.8	-1.0	-0.9	0.1	-2.8	-0.9
Leg fat-free mass (right)	0.3	1.4	8.1	1.4	1.0	-1.2	0.1	-0.6	-0.2	-0.6	0.4	-2.8	-1.0
Commuting to job workplace: Walk	0.3	0.3	1.3	0.2	-0.1	1.1	0.4	0.2	0.5	0.3	0.5	1.1	-0.1
Illnesses of father: None of the above (group 1)	0.3	0.3	1.4	0.1	-0.3	0.7	0.6	1.2	0.2	-0.5	-0.5	-0.2	-0.0
Whole body water mass	0.3	1.7	8.5	1.3	0.9	-1.4	-0.1	-0.9	-1.1	-1.0	0.0	-2.9	-0.9
Leg predicted mass (right)	0.3	1.4	7.9	1.4	1.0	-1.2	0.1	-0.6	-0.1	-0.7	0.4	-2.8	-0.9
Ever taken oral contraceptive pill	0.3	0.4	0.9	0.3	0.3	0.8	0.4	0.9	0.2	0.3	0.9	0.7	0.8
Basal metabolic rate	0.3	1.9	10.0	1.8	1.4	-1.1	-0.0	-0.9	-0.7	-0.7	-0.0	-3.2	-0.9
Vascular/heart problems diagnosed by doctor	0.3	0.7	2.4	0.3	-0.2	-1.6	-0.4	1.4	0.6	0.5	1.0	0.6	0.8
Cholesterol lowering medication	0.3	0.5	2.7	-0.4	0.0	0.8	0.2	-0.3	-0.5	-1.6	-0.6	-0.2	0.6
Basal cell carcinoma (self-reported)	0.3	0.4	0.9	-0.1	-0.3	-0.3	0.5	0.9	0.9	0.7	0.9	0.5	0.0
Impedance of whole body	0.3	1.3	3.8	-0.1	-0.5	0.5	-1.4	-1.4	1.0	1.7	-2.0	0.9	-0.6
Arm predicted mass (left)	0.3	1.7	7.3	2.0	1.6	-1.1	-0.0	-1.0	-0.6	-0.3	0.1	-2.7	-0.5
Ovarian Cancer	0.2	0.3	1.0	-0.8	-1.0	-0.2	-0.5	0.0	0.1	-0.7	0.2	0.7	0.4
Lupus	0.2	0.3	1.4	-0.1	-0.6	0.5	0.3	0.6	0.5	-0.3	0.1	0.8	1.2
Blood White Count	0.2	1.2	5.5	1.8	0.6	0.2	-0.2	-0.8	2.4	0.6	0.3	-0.3	-1.1
Cardiovascular Disease	0.2	0.8	4.3	0.2	0.4	2.1	0.8	-0.8	-0.7	-0.7	-0.8	-0.3	-0.3
Hair Pigment	0.2	5.1	10.5	1.2	1.6	1.7	1.3	1.6	3.1	2.6	2.3	3.2	2.7
Angina	0.2	0.3	1.9	-0.0	-0.0	0.2	0.1	0.1	-0.2	-1.4	-0.6	0.1	0.7
Impedance of leg (right)	0.2	1.0	4.2	-0.1	-0.1	0.2	-1.4	-1.2	-0.4	1.4	-2.1	0.4	-0.4
Average weekly fortified wine intake	0.2	0.3	0.8	0.4	-0.8	0.4	0.2	-0.1	-0.1	0.9	0.3	-0.5	-0.8
Medication: Levothyroxine sodium	0.2	0.4	1.3	0.7	-0.4	0.7	0.7	0.1	1.2	-0.3	0.6	0.9	0.3
Impedance of leg (left)	0.2	1.1	4.0	0.2	-0.1	0.5	-1.5	-1.0	-0.0	1.8	-2.0	0.8	-0.3
Forced vital capacity (FVC)	0.2	0.7	3.0	-0.1	-0.4	-1.7	-1.0	-0.4	-0.2	-0.8	-0.8	-0.8	-1.1
Allergy	0.2	0.4	1.5	-1.2	-0.5	0.4	-0.2	-0.2	-0.3	-0.3	-1.1	0.4	0.5
Pulse rate	0.2	0.4	1.5	0.5	1.2	-0.2	0.7	0.9	0.3	-0.3	0.1	-0.7	-0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.5	1.5	-0.7	-0.7	-1.2	-0.9	-0.2	-0.5	-0.9	-0.4	-0.4	-0.6
Impedance of arm (left)	0.2	1.1	2.7	-0.7	-0.8	0.1	-1.2	-1.1	1.5	1.1	-1.6	0.8	-0.7
Medication: Ventolin 100micrograms inhaler	0.2	0.3	1.2	0.1	-0.1	0.1	0.7	0.2	0.5	0.3	1.1	-0.3	-0.6
Heart disease (mother)	0.2	0.2	1.0	0.3	0.0	-0.2	0.1	-0.6	-0.0	-1.0	-0.1	0.6	0.7
Had major operations	0.2	0.2	0.7	0.9	0.2	0.6	0.6	0.3	-0.1	0.5	0.3	0.1	-0.2
Medication: Aspirin	0.2	0.3	0.7	-0.7	-0.7	0.4	-0.0	-0.1	-0.8	-0.5	-0.6	0.2	0.5
Hypertension (Self-reported)	0.2	0.7	3.0	0.3	0.9	1.7	0.8	-0.9	-0.3	-0.2	-0.4	-0.7	-0.6
Average weekly red wine intake	0.2	0.3	1.2	0.5	0.9	0.4	-0.2	0.3	-0.8	0.1	-0.2	-1.1	0.2
Medication: Aspirin	0.2	0.3	1.0	-0.8	-1.0	0.2	-0.3	-0.6	-0.7	-0.4	-0.6	-0.0	0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.5	1.0	-0.7	-0.3	-0.8	-0.3	-1.0	0.7	-0.7	0.6	0.7	0.9
Guilty feelings	0.2	0.4	1.2	0.6	1.1	-0.3	-0.4	0.2	-0.1	0.9	0.1	-0.6	-0.7
Medication: Blood pressure	0.2	0.3	0.9	0.5	-0.3	0.5	-0.1	-0.9	0.5	0.5	-0.9	-0.0	-0.3
Illnesses of father: High blood pressure	0.2	0.3	1.0	0.0	0.5	-0.3	-0.4	-0.9	0.2	1.0	0.2	0.2	0.7
Average weekly beer plus cider intake	0.2	0.3	0.8	0.4	0.9	-0.7	-0.1	-0.5	-0.4	0.2	0.3	0.8	-0.2
Irritability	0.2	0.3	0.8	0.2	0.2	0.1	0.5	0.7	-0.9	0.7	0.2	-0.7	-0.3
Age started oral contraceptive pill	0.2	0.3	1.3	0.7	0.4	0.7	-0.4	0.5	1.1	0.0	-0.3	0.4	-0.1
Blood Platelet Count	0.1	0.6	2.0	-0.8	-0.8	-0.3	-1.2	-0.1	0.6	-0.3	-0.9	1.4	-0.4
Allergy or Eczema	0.1	0.3	1.0	-0.0	-0.1	0.1	-0.7	-0.8	0.2	-0.3	0.3	0.9	1.0
Hayfever, allergic rhinitis or eczema	0.1	0.2	0.7	0.6	-0.0	-0.5	-0.7	-0.8	-0.3	-0.1	0.4	0.2	-0.0
Medication: Ramipril	0.1	0.1	0.5	-0.6	-0.4	0.7	-0.0	0.1	-0.1	0.1	0.4	-0.1	0.1
Noisy workplace	0.1	0.2	0.9	-0.1	0.4	0.7	0.0	0.0	0.1	0.1	-1.0	0.3	0.4
Hypothyroidism/myxoedema (self-reported)	0.1	0.2	0.8	0.0	-0.9	-0.1	-0.4	-0.2	0.7	-0.4	-0.1	-0.2	-0.8
Forced vital capacity (FVC), Best measure	0.1	0.3	0.9	0.2	0.3	-0.8	0.0	0.7	0.1	-1.0	-0.1	-0.8	-0.5
Tinnitus: Yes, now most or all of the time	0.1	0.1	0.4	-0.3	-0.2	-0.6	-0.2	0.0	0.4	0.2	0.2	0.4	0.5
Number of operations (self-reported)	0.1	0.1	0.4	0.6	0.3	0.3	0.5	0.0	-0.3	0.1	-0.3	0.6	0.4
Breast Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Tanning	0.0	0.3	1.0	1.0	0.4	-0.1	0.1	-0.8	-0.7	-0.7	0.1	-0.4	0.6

Hub : Genes

GCN1L1

Models

Trait associations