TWAS hub - GFI1B

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	YFS	Blood	0.0244	0.0117	1.4e-02	0.026	0.004	0.024	0.018	0.023	6.0e-09	1.3e-02	1.6e-08	7.5e-07	2.7e-08
2	TCGA	Brain Lower Grade Glioma	0.1638	0.0464	9.9e-07	0.109	0.061	0.109	NA	0.102	2.4e-12	1.7e-07	2.4e-12	NA	1.2e-11

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Back pain experienced in last month	6.3	9.2	14.9	-1.9	-3.9
Blood Eosinophil Count	5.8	44.6	52.6	-7.2	-6.0
Blood Red Count	4.4	43.0	85.9	-9.3	0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	4.1	4.9	5.4	-2.1	2.3
Had other major operations	3.5	4.3	5.0	-1.9	-2.2
Emphysema/chronic bronchitis	3.3	3.7	6.2	2.5	-1.1
Exposure to tobacco smoke outside home	2.9	3.8	7.6	-2.8	-0.3
Bipolar Disorder (2018)	2.8	4.4	7.3	1.2	-2.7
Family relationship satisfaction	2.7	3.4	4.4	2.1	1.5
Average weekly red wine intake	2.6	3.8	7.6	2.7	0.4
Heart disease (siblings)	2.4	2.9	4.6	1.1	-2.1
Diabetes (mother)	2.3	2.9	3.6	-1.9	1.5
Medication: Simvastatin	2.3	3.4	5.8	2.4	-1.0
Illness, injury, bereavement, stress in last 2 years	2.3	2.8	4.6	1.0	-2.1
HbA1C	2.1	2.4	4.6	-2.2	0.3
Loud music exposure frequency	2.1	2.3	4.7	2.2	0.1
Supplements: Zinc	2.0	2.2	4.3	2.1	-0.2
Serious illness, injury or assault of a close relative in last 2 years	2.0	2.3	4.6	-2.1	-0.0
Lung cancer (father)	2.0	2.3	4.4	0.5	2.1
Handedness (chirality/laterality): Left-handed	2.0	2.4	4.7	2.2	-0.1
Osteoporosis (self-reported)	2.0	2.4	4.7	-2.2	-0.3
Gout (self-reported)	1.9	2.6	5.2	0.1	2.3
Eye problems/disorders: Cataract	1.9	2.1	3.2	-1.8	1.1
Supplements: Calcium	1.9	2.1	4.2	0.1	-2.1
Primary Biliary Cirrhosis	1.8	2.5	3.3	1.3	1.8
Eye problems/disorders: Diabetes related eye disease	1.8	2.0	2.2	-1.5	-1.4
Hearing difficulty/problems with background noise	1.8	2.9	5.9	-0.1	2.4
Medication: Allopurinol	1.8	2.4	4.8	-0.4	2.2
Alcohol drinker status: Previous	1.8	2.1	4.1	-2.0	-0.3
Medication: Atenolol	1.7	2.1	2.3	1.5	-1.4
Number of live births	1.7	2.4	3.6	-1.9	-1.1
Average weekly champagne plus white wine intake	1.7	2.3	4.6	0.0	2.1
Rheumatoid Arthritis	1.6	2.2	3.1	1.1	1.8
Type 2 Diabetes (T2D) (2012)	1.6	1.8	3.6	-1.9	0.0
Pain all over the body in last month	1.6	1.7	3.0	-1.7	0.7
Blood clot in the leg (DVT)	1.6	2.1	3.8	0.6	1.9
Mouth/teeth dental problems: Loose teeth	1.6	1.9	2.8	1.0	-1.7
Deep venous thrombosis (DVT) (self-reported)	1.6	2.0	2.9	1.1	1.7
Crohns Disease (2017)	1.5	3.3	3.7	-1.9	1.7
Blood Platelet Count	1.5	17.7	29.5	-2.4	-5.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.5	1.7	2.8	-1.7	-0.8
Average weekly beer plus cider intake	1.5	2.1	4.2	0.4	-2.0
Breast Cancer	1.4	3.3	4.6	-2.2	-1.4
Medication for hormone replacement therapy	1.4	1.5	2.0	1.0	1.4
Eye problems/disorders: None of the above	1.4	1.7	2.6	1.6	-0.9
Fractured/broken bones in last 5 years	1.4	1.9	1.9	1.4	-1.4
Bipolar Disorder or Schizophrenia	1.3	3.2	4.8	1.2	-2.2
Bipolar Disorder (2011)	1.3	1.2	2.4	-1.6	0.0
High blood pressure (mother)	1.3	1.8	3.3	0.6	-1.8
Number of incorrect matches in round	1.3	2.1	2.5	-1.6	1.3
Tense / ‘highly strung’	1.3	2.1	4.0	-2.0	0.4
Birth weight of first child	1.3	2.3	3.9	0.8	-2.0
Medication for cholesterol, blood pressure or diabetes	1.3	2.2	3.7	-0.8	1.9
Financial situation satisfaction	1.3	1.6	3.1	-0.0	-1.8
Crohns Disease (2012)	1.2	2.0	2.4	-1.5	1.2
Severe depression (siblings)	1.2	1.3	2.4	-1.5	-0.5
Medication: Cholesterol lowering	1.2	1.9	2.6	1.6	-1.1
Seen doctor (GP) for nerves, anxiety, tension or depression	1.2	1.8	2.3	-1.1	-1.5
Migraine (self-reported)	1.2	1.5	2.3	-1.5	0.8
Long-standing illness, disability or infirmity	1.2	1.9	3.3	-0.7	-1.8
Schizophrenia vs Biploar Disorder	1.1	1.4	2.9	1.7	0.0
Alzheimer’s Disease (in father)	1.1	1.2	2.4	-1.6	0.1
Mean Putamen Volume	1.1	1.3	2.0	1.4	-0.8
Average weekly spirits intake	1.1	1.3	2.3	-1.5	-0.6
Hand grip strength (right)	1.1	3.0	5.9	-2.4	0.5
Relative age voice broke	1.1	1.7	2.8	-0.8	-1.7
Tinnitus: Yes, but not now, but have in the past	1.1	1.2	2.4	0.1	-1.5
Serious illness, injury or assault to yourself	1.1	1.3	1.3	-1.1	1.1
Diverticular disease/diverticulitis (self-reported)	1.1	1.3	1.7	-1.3	0.9
Heart attack	1.1	1.4	1.4	1.1	-1.2
Prospective memory result	1.1	1.4	1.9	-0.9	-1.4
Reason for reducing amount of alcohol drunk: Health precaution	1.1	1.3	2.1	-1.5	0.7
Ever had stillbirth, spontaneous miscarriage or termination	1.1	1.2	1.4	-1.2	-1.0
Mineral and other dietary supplements	1.1	1.5	2.7	1.6	0.5
Medication: Lisinopril	1.1	1.4	2.7	0.3	-1.6
Ever depressed for a whole week	1.1	1.4	1.8	1.0	-1.3
Hearing difficulty/problems: Yes	1.0	1.5	2.4	0.7	1.6
Age when periods started (menarche)	1.0	2.5	3.7	1.9	-1.1
Alcohol intake versus 10 years previously	1.0	1.6	1.6	-1.2	-1.3
Medication: Paracetamol	1.0	1.7	3.0	-1.7	-0.7
Medication: Ibuprofen	1.0	1.2	1.4	1.0	-1.2
Heart attack/myocardial infarction (self-reported)	1.0	1.3	1.5	1.0	-1.2
Systolic blood pressure, automated reading	0.9	2.6	4.6	-0.7	2.2
Diabetes (father)	0.9	1.1	1.9	0.5	-1.4
Qualifications: O levels/GCSEs or equivalent	0.9	1.4	2.7	1.6	-0.3
Neck or shoulder pain in last month	0.9	1.3	1.3	1.2	-1.1
Age at last live birth	0.9	1.2	1.4	-1.2	-1.1
Friendships satisfaction	0.9	1.1	2.2	1.5	-0.2
Hearing aid user	0.9	1.0	1.9	1.4	-0.3
Blood White Count	0.8	6.0	7.8	-2.8	-2.1
Systolic Blood Pressure	0.8	4.2	5.0	-1.9	2.2
Angina	0.8	1.0	1.1	1.1	-1.0
Medication: Metformin	0.8	1.1	1.6	1.3	-0.8
Asthma	0.8	1.5	1.8	-1.1	-1.4
Birth weight	0.8	1.8	3.0	1.7	-0.8
Comparative body size at age 10	0.8	2.1	4.1	2.0	-0.1
Number of children fathered	0.8	0.9	1.1	1.1	-0.8
Illnesses of siblings: Diabetes	0.8	1.0	1.9	-1.4	-0.3
Asthma (self-reported)	0.8	1.7	2.2	-1.1	-1.5
Mother’s age at death	0.8	1.0	1.4	-1.2	0.8
Tinnitus: Yes, now most or all of the time	0.8	0.9	1.3	1.1	0.8
Supplements: Fish oil (including cod liver oil)	0.8	1.1	1.9	-1.4	-0.5
Age started oral contraceptive pill	0.8	1.0	1.0	-1.0	-1.0
Hand grip strength (left)	0.7	1.8	3.2	-1.8	0.6
Frequency of depressed mood in last 2 weeks	0.7	1.0	2.1	-1.4	-0.0
Vitamin and mineral supplements	0.7	0.9	1.3	1.1	-0.8
Taking other prescription medications	0.7	1.1	1.9	-1.4	-0.5
Hair/balding pattern: Pattern 3	0.7	1.1	2.2	0.1	1.5
Mouth/teeth dental problems: Dentures	0.7	1.1	1.1	1.1	-1.1
Glaucoma (self-reported)	0.7	0.8	1.6	-0.1	1.3
Medication: Ventolin 100micrograms inhaler	0.7	0.8	1.0	1.0	-0.8
Wheeze or whistling in the chest in last year	0.7	1.2	1.3	1.1	-1.1
Medication: Seretide 50 evohaler	0.7	0.8	1.4	0.3	-1.2
Qualifications: NVQ or HND or HNC or equivalent	0.7	0.8	1.3	-1.2	0.5
Knee pain experienced in last month	0.7	1.1	2.1	1.4	-0.5
Qualifications: nursing, teaching	0.7	1.1	2.1	0.4	-1.4
Irritable Bowel Disease (IBD)	0.6	1.5	1.8	-1.0	1.4
Age at First Birth	0.6	0.8	1.5	-0.3	1.2
HDL Cholesterol	0.6	1.0	1.2	0.9	-1.1
Heel T-Score	0.6	4.8	7.6	-2.8	1.4
Smoking Status	0.6	1.4	2.3	1.5	0.7
Medication: Co-codamol	0.6	0.7	1.3	-0.4	-1.1
Hayfever, allergic rhinitis or eczema	0.6	1.3	2.5	-0.2	1.6
Supplements: Glucosamine	0.6	0.8	1.7	-1.3	0.1
Chronic bronchitis/emphysema (father)	0.6	0.7	1.1	-0.5	-1.0
Hair/balding pattern: Pattern 2	0.6	0.7	1.0	-1.0	-0.7
Allergy	0.6	1.4	2.6	0.3	-1.6
Illnesses of siblings	0.6	0.9	1.7	-0.0	1.3
Time employed in main current job	0.6	0.7	1.5	1.2	0.1
Falls in the last year	0.6	0.8	1.0	0.8	1.0
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.7	1.2	0.5	-1.1
Number of full brothers	0.6	0.8	1.2	1.1	0.6
Alcohol intake frequency.	0.6	1.3	1.5	-1.2	-1.1
Number of full sisters	0.6	0.8	0.8	-0.9	-0.9
Overall health rating	0.6	1.2	1.5	-1.0	-1.2
Miserableness	0.6	1.0	1.7	-1.3	-0.6
Eye problems/disorders: Glaucoma	0.6	0.7	0.8	-0.8	0.9
High cholesterol (Self-reported)	0.6	1.1	2.3	1.5	0.1
Medication: Atorvastatin	0.6	0.8	1.3	-0.5	-1.1
Ever had prostate specific antigen (PSA) test	0.6	0.7	1.0	0.7	1.0
Intelligence (Savage-Jansen 2018)	0.5	1.6	2.7	0.7	1.6
Schizophrenia (2018)	0.5	1.0	1.5	0.7	-1.2
Allergy or Eczema	0.5	1.3	1.6	-1.2	1.0
Hypothyroidism (self reported)	0.5	1.2	2.4	-0.2	-1.6
Respiratory disease	0.5	1.1	1.8	-0.7	-1.3
Number of treatments/medications taken	0.5	0.9	1.7	-0.1	-1.3
Relative age of first facial hair	0.5	1.0	1.9	-1.4	0.0
Maternal smoking around birth	0.5	0.7	1.0	1.0	-0.6
Qualifications: CSEs or equivalent	0.5	0.7	0.7	0.8	0.8
Hayfever/allergic rhinitis (self-reported)	0.5	0.6	1.3	-1.1	-0.1
Exposure to tobacco smoke at home	0.5	0.5	1.0	-0.3	-1.0
Medication: Amlodipine	0.5	0.6	0.7	0.8	-0.8
Chronic bronchitis/emphysema (mother)	0.5	0.6	0.9	0.6	-1.0
Age at first live birth	0.5	0.9	1.3	-1.1	-0.7
Commuting to job workplace: Public transport	0.5	0.6	1.1	1.0	0.4
Pain type(s) experienced in last month: Hip pain	0.5	0.7	0.8	-0.9	-0.7
Medication: Paracetamol	0.5	0.8	1.1	-1.0	-0.8
Number of operations (self-reported)	0.5	0.8	1.5	-0.1	-1.2
Risk taking	0.5	0.7	1.4	-0.2	1.2
Diastolic blood pressure, automated reading	0.5	1.5	2.9	-0.3	1.7
Myopia	0.5	0.7	1.5	1.2	-0.0
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	0.7	0.9	-0.7
Pain experienced in last month	0.5	0.9	1.6	0.4	1.3
Verbal and Numeric Reasoning (VNR)	0.4	0.9	1.2	1.1	-0.7
Body Mass Index (BMI) (2010)	0.4	0.5	0.9	-0.9	-0.5
Schizophrenia (2014)	0.4	0.9	1.5	1.2	-0.6
Triglycerides	0.4	0.6	1.0	-1.0	0.5
Pack years adult smoking proportion	0.4	0.6	1.2	-0.2	1.1
Impedance of leg (right)	0.4	2.0	2.1	-1.4	1.4
Average weekly fortified wine intake	0.4	0.5	0.9	-1.0	-0.2
Impedance of leg (left)	0.4	2.0	3.4	-1.8	0.8
Past tobacco smoking	0.4	0.7	0.9	-0.9	0.7
Heel bone mineral density (BMD) T-score, automated (right)	0.4	0.9	1.8	-1.4	-0.1
Ever unenthusiastic/disinterested for a whole week	0.4	0.4	0.5	0.7	-0.6
Medication: Lansoprazole	0.4	0.4	0.8	-0.9	0.2
Breastfed as a baby	0.4	0.5	1.0	1.0	-0.1
High blood pressure (siblings)	0.4	0.6	1.0	-0.4	-1.0
Worry too long after embarrassment	0.4	0.7	0.7	-0.8	0.9
Medication: Blood pressure	0.4	0.8	1.2	0.6	-1.1
Angina (self-reported)	0.4	0.5	0.9	0.9	-0.4
Chest pain or discomfort	0.4	0.6	1.1	-1.1	0.4
Leg pain on walking	0.4	0.5	0.8	0.5	-0.9
Breast cancer (self-reported)	0.4	0.5	0.7	-0.5	-0.9
Wears glasses or contact lenses	0.4	0.4	0.6	0.8	-0.5
Medication: Bendroflumethiazide	0.4	0.7	1.3	0.0	-1.1
Illnesses of father: High blood pressure	0.4	0.5	0.9	0.9	-0.5
Commuting to job workplace: Cycle	0.4	0.5	1.0	-1.0	-0.0
Cholesterol lowering medication	0.4	0.5	0.7	0.5	-0.9
Alzheimer’s Disease (including proxy)	0.3	0.4	0.5	-0.7	-0.5
Ulcerative Colitis	0.3	0.5	1.0	1.0	0.0
Chronotype (morning person)	0.3	0.6	0.9	-0.5	-1.0
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.7	1.3	-1.1	-0.4
Stomach or abdominal pain in last month	0.3	0.4	0.7	0.0	0.8
Body mass index (BMI)	0.3	1.3	2.1	0.7	-1.4
Waist circumference	0.3	1.2	1.4	1.0	-1.2
Forced vital capacity (FVC)	0.3	1.2	2.3	-1.5	0.2
Medication: Ramipril	0.3	0.4	0.4	0.6	-0.7
Weight	0.3	1.3	2.1	0.6	-1.5
Arm fat percentage (right)	0.3	1.1	1.4	1.2	-0.9
Pulse rate	0.3	0.5	1.0	-1.0	0.0
Happiness	0.3	0.4	0.6	0.4	-0.8
Noisy workplace	0.3	0.4	0.7	0.2	0.9
Pulse wave reflection index	0.3	0.3	0.7	0.2	0.8
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	0.7	-0.9	0.3
Hypothyroidism/myxoedema (self-reported)	0.3	0.5	1.1	0.0	-1.0
Shortness of breath walking on level ground	0.3	0.4	0.6	-0.8	-0.4
Medication for pain relief, constipation, heartburn	0.3	0.5	0.6	0.8	0.6
Medication: Omeprazole	0.3	0.3	0.7	0.8	-0.1
Had major operations	0.3	0.4	0.8	0.9	0.1
Smoking status: Previous	0.3	0.4	0.7	0.8	-0.3
Arm fat percentage (left)	0.3	1.3	1.9	1.4	-0.8
Mood swings	0.3	0.6	0.6	-0.7	-0.8
Diabetes diagnosed by doctor	0.3	0.4	0.8	0.9	0.3
Mouth/teeth dental problems: Mouth ulcers	0.3	0.5	1.0	-1.0	0.2
Medication for cholesterol	0.3	0.4	0.6	-0.8	0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.7	1.4	0.0	1.2
Number of self-reported non-cancer illnesses	0.3	0.6	0.8	-0.9	-0.6
Ever smoked	0.3	0.6	0.8	-0.6	-0.9
Pack years of smoking	0.3	0.4	0.7	0.1	0.9
Reaction Time	0.2	0.4	0.7	-0.1	0.9
LDL Cholesterol	0.2	0.4	0.7	0.8	0.3
Neuroticism (2016)	0.2	0.3	0.5	-0.1	-0.7
Lung FVC	0.2	0.9	1.8	-0.0	1.4
Sensitivity / hurt feelings	0.2	0.3	0.5	0.7	0.0
Ever used hormone-replacement therapy (HRT)	0.2	0.2	0.4	-0.3	0.6
Leg fat-free mass (left)	0.2	1.0	1.6	1.3	-0.6
Fed-up feelings	0.2	0.3	0.3	-0.6	-0.6
Leg predicted mass (left)	0.2	0.9	1.5	1.2	-0.5
Financial difficulties in last 2 years	0.2	0.3	0.4	-0.6	-0.5
Diabetes (self-reported)	0.2	0.3	0.4	0.5	0.6
Fluid intelligence score	0.2	0.3	0.4	0.5	-0.6
Impedance of arm (right)	0.2	0.9	1.4	1.2	0.7
Hip circumference	0.2	0.7	0.9	1.0	-0.7
Worrier / anxious feelings	0.2	0.5	0.9	-0.9	0.2
Forced expiratory volume in 1-second (FEV1)	0.2	0.7	1.5	-1.2	0.2
Illnesses of mother	0.2	0.2	0.3	0.5	0.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.6	0.9	-0.9	0.5
Arm fat mass (right)	0.2	0.9	1.4	0.6	-1.2
Length of working week for main job	0.2	0.2	0.4	0.1	0.6
Peak expiratory flow (PEF)	0.2	0.5	0.9	-0.9	-0.4
Forced vital capacity (FVC), Best measure	0.2	0.8	1.5	-1.2	0.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.3	0.4	0.3	0.7
Health satisfaction	0.2	0.3	0.4	-0.6	-0.3
Whole body fat mass	0.2	0.8	1.3	0.6	-1.1
Leg fat mass (right)	0.2	0.7	1.4	0.3	-1.2
Comparative height size at age 10	0.2	1.1	1.9	0.6	-1.4
Medication: Aspirin	0.2	0.2	0.3	-0.3	0.6
Leg fat-free mass (right)	0.2	1.0	1.3	1.1	-0.8
Loneliness, isolation	0.2	0.3	0.4	-0.6	0.4
Ever had bowel cancer screening	0.2	0.2	0.4	0.7	-0.1
Medication: Gliclazide	0.2	0.3	0.5	0.7	0.1
Smoking status: Current	0.2	0.2	0.5	0.7	-0.1
Leg predicted mass (right)	0.2	1.0	1.3	1.1	-0.8
Arm fat mass (left)	0.2	0.8	1.0	0.8	-1.0
Guilty feelings	0.2	0.3	0.5	0.3	0.7
Ever taken oral contraceptive pill	0.2	0.2	0.2	-0.4	0.5
Medication: Blood pressure	0.2	0.4	0.4	0.6	-0.6
Leg fat mass (left)	0.2	0.9	1.7	0.2	-1.3
Depression (Nagel 2018)	0.1	0.2	0.2	-0.5	0.3
Worry (Nagel 2018)	0.1	0.1	0.1	-0.3	0.4
Alzheimer’s Disease (in mother)	0.1	0.1	0.1	0.0	0.3
Ulcerative Colitis (UC)	0.1	0.2	0.3	0.3	0.5
Major Depression (MDD)	0.1	0.2	0.3	-0.6	0.0
Ovarian Cancer	0.1	0.1	0.2	-0.5	-0.0
Coronary Artery Disease (CAD)	0.1	0.1	0.2	-0.4	0.0
Fasting Glucose	0.1	0.1	0.1	0.3	0.3
BMI	0.1	0.7	1.3	-0.1	-1.1
Height	0.1	1.3	1.4	-1.2	1.0
Waist Hip Ratio (WHR)	0.1	0.2	0.3	-0.5	-0.4
Cardiovascular Disease	0.1	0.5	1.0	1.0	-0.0
Other serious medical condition/disability diagnosed by doctor	0.1	0.1	0.1	0.3	-0.2
Trunk fat percentage	0.1	0.6	0.8	0.9	-0.6
Current tobacco smoking	0.1	0.2	0.4	0.6	-0.0
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.1	0.2	-0.5	-0.1
Bilateral oophorectomy (both ovaries removed)	0.1	0.1	0.2	-0.5	0.3
Multivitamins +/- minerals	0.1	0.2	0.4	-0.6	0.1
Medication: Levothyroxine sodium	0.1	0.1	0.1	0.2	0.4
Sitting height	0.1	1.1	2.1	-1.4	0.0
Trunk fat mass	0.1	0.6	0.6	0.8	-0.7
Alcohol usually taken with meals	0.1	0.1	0.2	-0.1	0.4
Nervous feelings	0.1	0.1	0.2	-0.5	-0.3
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.1	0.2	-0.5	0.1
Had menopause	0.1	0.1	0.2	-0.4	-0.2
Neuroticism score	0.1	0.2	0.4	-0.6	0.2
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.1	0.2	-0.4	0.2
Depression (self-reported)	0.1	0.1	0.2	0.1	-0.4
Pulse wave Arterial Stiffness index	0.1	0.1	0.1	0.4	-0.3
Impedance of arm (left)	0.1	0.6	1.1	1.1	0.3
Hair/balding pattern: Pattern 4	0.1	0.2	0.4	0.6	-0.2
Ever highly irritable/argumentative for 2 days	0.1	0.2	0.3	0.3	0.5
Body fat percentage	0.1	0.4	0.4	0.7	-0.7
Leg fat percentage (right)	0.1	0.2	0.4	0.2	-0.7
Arm predicted mass (right)	0.1	0.5	0.6	-0.8	-0.6
Pulse rate, automated reading	0.1	0.5	0.9	-0.9	-0.2
Suffer from ‘nerves’	0.1	0.2	0.3	-0.0	0.6
Supplements: Vitamin C	0.1	0.2	0.2	-0.4	-0.4
Osteoarthritis (self-reported)	0.1	0.1	0.1	-0.4	-0.1
Medication: Aspirin	0.1	0.1	0.3	0.0	0.5
Alcohol drinker status: Never	0.1	0.1	0.1	0.3	-0.2
Basal metabolic rate	0.1	0.4	0.6	0.5	-0.8
Leg fat percentage (left)	0.1	0.5	0.9	0.1	-1.0
Arm fat-free mass (left)	0.1	0.3	0.4	-0.5	-0.6
Unable to work because of sickness or disability	0.1	0.1	0.2	-0.4	-0.4
Vascular/heart problems diagnosed by doctor	0.1	0.2	0.4	-0.2	0.6
Impedance of whole body	0.1	0.5	0.6	-0.7	0.8
Depressed Affect (Nagel 2018)	0.0	0.0	0.0	-0.0	0.1
Neuroticism (Nagel 2018)	0.0	0.1	0.1	-0.2	0.3
Prostate Cancer	0.0	0.0	0.0	0.0	0.0
Lupus	0.0	0.0	0.0	0.2	0.1
Type 2 Diabetes (T2D) (2018)	0.0	0.0	0.1	-0.1	0.2
Lung FEV1/FVC ratio	0.0	0.2	0.4	-0.2	0.6
Neuroticism	0.0	0.1	0.1	-0.3	0.2
Hair Pigment	0.0	0.9	1.8	-0.3	-1.3
Tanning	0.0	0.2	0.3	-0.2	0.5
Ever had hysterectomy (womb removed)	0.0	0.0	0.0	-0.0	0.0
Townsend deprivation index at recruitment	0.0	0.0	0.1	-0.3	0.0
High blood pressure	0.0	0.1	0.1	0.3	-0.3
Qualifications: None of the above	0.0	0.0	0.0	0.2	0.1
Mouth/teeth dental problems	0.0	0.0	0.0	0.2	-0.0
Trunk fat-free mass	0.0	0.1	0.2	0.1	-0.5
Father’s age at death	0.0	0.0	0.0	-0.1	0.0
Qualifications: A levels/AS levels or equivalent	0.0	0.0	0.1	0.3	-0.0
Trunk predicted mass	0.0	0.1	0.3	0.1	-0.5
Standing height	0.0	0.1	0.1	-0.3	-0.3
Headache pain in last month	0.0	0.0	0.0	-0.0	0.2
Arm fat-free mass (right)	0.0	0.2	0.2	-0.5	-0.3
Pulse wave peak to peak time	0.0	0.0	0.0	-0.2	0.2
Qualifications: College or University degree	0.0	0.2	0.3	0.2	-0.5
Mean time to correctly identify matches	0.0	0.0	0.1	-0.2	0.2
Heart disease (mother)	0.0	0.0	0.0	0.0	0.2
Commuting to job workplace: Car/motor vehicle	0.0	0.0	0.0	-0.1	0.1
Hypertension (Self-reported)	0.0	0.1	0.3	0.5	0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.0	0.1	0.1	-0.3	-0.1
Illnesses of father: Heart disease	0.0	0.0	0.0	0.1	0.1
Forced expiratory volume in 1-second (FEV1), predicted	0.0	0.0	0.1	0.1	0.3
Whole body fat-free mass	0.0	0.3	0.3	0.5	-0.5
Commuting to job workplace: Walk	0.0	0.0	0.0	-0.2	-0.1
Illnesses of father: None of the above (group 1)	0.0	0.1	0.1	-0.2	0.3
Whole body water mass	0.0	0.2	0.4	0.3	-0.6
Irritability	0.0	0.1	0.1	-0.1	0.3
Basal cell carcinoma (self-reported)	0.0	0.0	0.0	0.0	-0.1
Arm predicted mass (left)	0.0	0.2	0.3	-0.4	-0.5

Hub : Genes

GFI1B

Models

Trait associations