Hub : Genes

GMCL1

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0640	0.0240	3.1e-06	0.089	0.061	0.081	0.073	0.085	6.5e-11	5.5e-08	3.9e-10	3.0e-09	1.5e-10
2	GTEx	Adipose Subcutaneous	0.0320	0.0170	8.5e-03	0.040	NA	0.019	NA	0.016	3.3e-04	NA	1.0e-02	NA	1.7e-02
3	GTEx	Adipose Visceral Omentum	0.0740	0.0380	5.7e-03	0.037	NA	0.000	NA	0.012	4.9e-03	NA	3.1e-01	NA	7.4e-02
4	GTEx	Brain Cerebellum	0.1300	0.0640	6.0e-03	0.114	NA	0.054	NA	0.105	3.1e-04	NA	1.1e-02	NA	5.1e-04
5	GTEx	Muscle Skeletal	0.1326	0.0405	3.4e-08	0.068	NA	0.097	NA	0.112	3.0e-07	NA	8.9e-10	NA	4.5e-11
6	NTR	Blood	0.0563	0.0160	2.9e-12	0.046	0.044	0.044	0.044	0.048	1.1e-14	4.1e-14	4.9e-14	4.4e-14	4.4e-15
7	ROSMAP	Brain Pre-frontal Cortex	0.1648	0.0414	0.0e+00	0.171	0.176	0.162	0.179	0.180	2.1e-21	5.2e-22	2.3e-20	1.8e-22	1.5e-22
8	YFS	Blood	0.0191	0.0088	1.6e-03	0.015	0.008	0.011	0.009	0.013	8.9e-06	6.4e-04	9.1e-05	6.0e-04	2.7e-05
9	TCGA	Head and Neck Squamous Cell Carcinoma	0.0269	0.0207	1.8e-03	0.025	0.016	0.012	NA	0.016	6.6e-04	5.7e-03	1.4e-02	NA	5.7e-03

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	0.6	1.0	2.2	-0.9	0.9	1.3	-0.8	-0.4	0.3	-1.1	1.5	1.2
Bipolar Disorder or Schizophrenia	1.0	2.4	3.6	-1.6	1.3	1.8	-1.4	-1.3	0.4	-1.7	1.8	1.9
Depressed Affect (Nagel 2018)	0.3	0.6	1.2	-0.7	1.1	0.5	-0.7	-1.0	0.6	-1.0	0.2	0.9
Depression (Nagel 2018)	0.0	0.1	0.2	0.2	-0.4	0.2	0.5	-0.3	-0.0	-0.1	0.1	-0.2
Intelligence (Savage-Jansen 2018)	3.0	9.2	14.6	3.1	-3.6	-3.1	3.2	2.0	-0.4	2.8	-3.8	-3.7
Neuroticism (Nagel 2018)	0.3	0.7	1.1	-0.8	1.1	0.7	-0.7	-0.9	0.9	-1.1	0.6	0.8
Schizophrenia (2018)	0.7	1.5	2.2	-1.3	1.0	1.3	-1.2	-1.4	0.3	-1.4	1.1	1.5
Schizophrenia vs Biploar Disorder	0.1	0.2	0.5	-0.4	0.1	0.4	-0.5	-0.5	0.7	-0.4	-0.3	0.2
Worry (Nagel 2018)	0.4	0.8	1.9	-1.0	0.8	0.7	-0.6	-0.7	0.4	-1.0	1.4	1.0
Alzheimer’s Disease (in mother)	0.7	0.9	3.6	-0.3	0.5	0.7	-0.1	-0.9	1.9	-1.0	-1.1	0.2
Alzheimer’s Disease (in father)	0.0	0.0	0.1	0.3	0.0	0.2	0.2	0.3	-0.0	-0.2	0.1	0.0
Alzheimer’s Disease (including proxy)	0.1	0.2	0.8	0.3	0.2	0.3	0.2	-0.0	0.9	-0.4	-0.8	-0.0
Crohns Disease (2017)	1.9	4.1	7.0	-2.0	2.1	1.8	-2.3	-2.6	2.4	-2.1	0.6	1.8
Irritable Bowel Disease (IBD)	1.4	3.2	5.4	-1.7	2.1	1.6	-2.1	-2.3	1.8	-1.6	0.6	1.7
Ulcerative Colitis (UC)	0.4	0.8	1.5	-0.7	1.1	1.0	-1.0	-1.2	0.5	-0.7	0.5	0.9
Major Depression (MDD)	1.4	1.6	3.9	-1.0	0.9	1.6	-0.9	-2.0	1.9	-1.2	0.5	0.6
Reaction Time	1.6	3.1	5.1	-2.2	1.8	1.4	-2.3	-1.9	1.0	-1.6	1.0	2.2
Verbal and Numeric Reasoning (VNR)	5.0	12.1	16.9	3.7	-4.0	-3.7	3.5	2.4	-1.3	3.6	-4.0	-4.1
Breast Cancer	3.4	8.1	17.5	-2.6	3.0	2.1	-2.8	-3.7	4.2	-3.0	-0.5	2.0
Ovarian Cancer	1.2	1.6	2.3	-1.1	1.3	1.4	-1.2	-1.5	1.4	-1.5	0.5	1.1
Prostate Cancer	0.2	0.2	0.6	-0.2	-0.3	0.4	-0.1	0.6	-0.6	0.2	0.8	0.5
Age at First Birth	0.2	0.2	0.7	0.4	-0.4	-0.8	0.4	0.1	-0.7	0.5	-0.3	-0.4
Bipolar Disorder (2011)	0.4	0.3	1.0	-0.2	0.3	0.8	0.0	-0.7	1.0	-0.8	-0.4	0.3
Body Mass Index (BMI) (2010)	1.0	1.4	3.0	1.3	-1.7	-0.7	1.6	1.1	-0.6	0.9	-0.8	-1.5
Coronary Artery Disease (CAD)	2.8	3.3	4.4	-2.1	1.7	2.1	-2.0	-1.5	1.6	-2.0	1.2	1.9
Crohns Disease (2012)	3.4	5.4	10.9	-2.3	2.1	2.0	-2.2	-3.0	3.3	-2.7	-0.1	1.9
Mean Putamen Volume	0.1	0.1	0.5	0.4	-0.4	-0.2	0.7	-0.1	-0.2	0.2	-0.2	-0.3
Fasting Glucose	0.4	0.5	2.0	0.3	-0.9	-0.4	0.5	0.9	-1.4	0.7	0.5	-0.1
HbA1C	0.7	0.7	2.3	-1.0	0.9	0.3	-1.5	0.1	-0.1	-0.6	0.9	1.2
HDL Cholesterol	0.2	0.4	0.5	-0.7	0.6	0.6	-0.6	0.4	-0.7	-0.0	0.7	0.7
LDL Cholesterol	0.5	0.8	3.5	0.3	0.5	-0.5	0.7	-0.7	1.2	-0.2	-1.9	-0.5
Lupus	0.9	1.4	2.5	-1.4	1.6	0.9	-1.2	-0.8	-0.0	-1.1	1.3	1.6
Neuroticism (2016)	1.9	2.7	5.0	-1.7	2.2	1.5	-1.9	-1.7	1.5	-1.4	0.6	1.7
Primary Biliary Cirrhosis	1.8	2.5	4.7	-1.5	1.9	2.2	-1.3	-1.2	0.8	-1.7	1.6	1.7
Rheumatoid Arthritis	0.6	0.9	2.2	-0.4	1.2	-0.5	-0.1	-1.4	1.2	-0.7	-1.5	0.1
Schizophrenia (2014)	2.3	5.2	8.8	-2.4	1.7	3.0	-2.1	-2.0	1.1	-2.5	2.4	2.7
Triglycerides	0.0	0.1	0.2	0.2	-0.0	-0.5	0.0	0.1	0.3	-0.1	-0.3	-0.4
Type 2 Diabetes (T2D) (2012)	2.5	2.9	4.9	-1.8	1.5	2.0	-1.6	-1.3	0.6	-1.8	2.2	2.0
Ulcerative Colitis	0.1	0.2	0.4	-0.3	0.3	0.5	-0.5	-0.5	0.2	-0.5	0.6	0.5
Blood Eosinophil Count	0.1	0.9	1.4	1.0	-1.2	-0.9	0.4	1.1	0.1	1.0	-1.2	-1.1
Blood Platelet Count	8.3	95.8	204.5	8.5	-9.7	-8.7	8.3	13.2	-14.3	11.3	1.3	-6.5
Blood Red Count	0.5	5.0	9.1	1.8	-2.2	-2.6	1.5	3.0	-3.0	2.7	-0.4	-1.5
Blood White Count	0.1	0.9	2.1	0.8	-0.9	-1.4	0.4	0.7	0.3	0.8	-1.4	-1.1
Heel T-Score	0.1	0.8	1.6	-0.7	0.9	1.2	-1.3	-0.8	-0.1	-0.5	0.9	1.0
BMI	1.1	6.2	10.0	-2.9	2.6	2.3	-3.2	-2.6	1.7	-2.5	1.6	2.6
Height	1.1	21.4	31.1	4.3	-5.6	-4.9	4.9	5.3	-4.8	4.9	-1.9	-4.1
Waist Hip Ratio (WHR)	0.5	2.1	4.0	1.6	-1.6	-1.1	0.9	2.0	-1.7	1.6	0.6	-1.3
Systolic Blood Pressure	0.1	0.6	2.3	-0.0	0.6	0.0	-1.0	0.4	-1.3	0.3	1.5	0.5
Smoking Status	0.1	0.2	0.6	0.6	-0.1	-0.3	0.4	0.3	0.0	0.4	-0.8	-0.5
Allergy or Eczema	0.4	0.9	1.6	0.8	-0.9	-1.3	1.3	1.2	-0.5	0.8	-0.7	-0.8
Cardiovascular Disease	1.6	5.4	9.9	-2.2	2.9	2.0	-2.5	-3.1	2.3	-2.4	0.3	2.0
Hypothyroidism (self reported)	0.4	0.8	3.3	0.2	0.3	0.2	0.7	-0.9	1.8	-0.8	-1.3	-0.5
Respiratory disease	0.0	0.1	0.4	0.1	0.2	0.2	0.6	0.2	-0.1	-0.3	0.4	0.2
Type 2 Diabetes (T2D) (2018)	0.3	0.5	1.1	-0.7	1.0	0.2	-1.0	-0.9	0.2	-0.5	-0.1	0.8
Lung FEV1/FVC ratio	0.4	2.1	4.5	-1.3	1.6	1.0	-1.4	-2.1	1.8	-1.4	-0.9	1.0
Lung FVC	2.1	10.4	21.4	2.9	-3.0	-2.5	3.2	4.6	-4.5	3.6	-0.1	-2.2
Neuroticism	0.8	1.9	3.3	-1.6	1.8	1.1	-1.3	-0.9	0.6	-1.4	1.4	1.7
Chronotype (morning person)	1.2	2.7	8.0	-1.6	1.9	1.0	-2.8	-0.6	-0.4	-0.7	2.2	2.0
Hair Pigment	0.2	5.6	21.1	0.6	0.7	0.2	0.5	-2.6	4.6	-1.4	-4.2	-1.5
Tanning	0.1	0.7	2.8	0.3	-0.6	-0.4	0.4	1.1	-1.7	0.9	0.8	0.0
Hand grip strength (left)	0.8	2.1	3.0	-1.5	1.4	1.7	-1.6	-1.7	1.6	-1.6	0.1	1.3
Number of treatments/medications taken	0.8	1.5	3.1	1.3	-0.9	-1.7	1.4	0.8	-0.7	1.1	-1.3	-1.3
Average weekly spirits intake	0.7	0.9	3.6	0.8	-0.4	-1.3	0.6	-0.1	0.2	0.8	-1.9	-1.0
Sensitivity / hurt feelings	2.0	3.3	5.1	-1.8	1.9	1.8	-1.9	-2.0	2.2	-2.1	0.8	1.5
Frequency of depressed mood in last 2 weeks	0.1	0.1	0.3	-0.1	0.1	0.3	0.2	-0.5	0.6	-0.5	0.1	-0.0
Hearing difficulty/problems: Yes	0.4	0.5	1.2	-0.9	1.1	0.3	-0.4	-0.8	0.2	-0.9	0.4	1.0
Relative age of first facial hair	0.3	0.7	2.9	-0.5	0.2	0.6	-0.5	0.3	-1.2	-0.2	1.7	0.9
Other serious medical condition/disability diagnosed by doctor	0.5	0.7	2.5	-0.5	0.1	0.4	-0.2	-1.4	1.6	-0.7	-0.9	0.1
Ever used hormone-replacement therapy (HRT)	0.1	0.1	0.3	0.0	-0.3	0.2	0.3	-0.2	0.6	-0.4	0.1	-0.2
Ever had hysterectomy (womb removed)	1.1	1.3	4.6	-0.3	0.1	0.0	-0.5	1.2	-2.1	0.7	2.0	0.8
Systolic blood pressure, automated reading	0.9	2.6	5.5	-1.5	1.9	1.3	-2.3	-1.3	0.8	-1.5	1.7	1.6
Eye problems/disorders: Diabetes related eye disease	0.5	0.5	1.0	-0.7	0.8	0.7	-0.7	-1.0	0.7	-0.8	-0.3	0.6
Angina	1.9	2.5	6.4	-1.6	1.7	0.9	-2.0	0.2	-0.8	-0.7	2.5	2.1
Medication for hormone replacement therapy	0.7	0.8	1.6	-0.9	0.6	1.2	-0.5	-0.3	0.2	-1.0	1.3	1.0
Vitamin and mineral supplements	0.4	0.5	2.4	-0.2	-0.1	1.1	-0.6	-0.3	-0.4	-0.3	1.6	0.3
Supplements: Zinc	0.2	0.2	0.7	-0.8	0.4	-0.1	-0.5	-0.3	-0.1	-0.3	0.7	0.6
Medication: Co-codamol	0.6	0.7	2.4	-0.2	0.1	0.0	-0.4	0.8	-1.6	0.4	1.5	0.6
Medication: Metformin	0.7	1.0	1.5	-0.9	1.1	0.9	-1.2	-1.2	1.0	-1.1	0.2	0.8
Diabetes (father)	0.2	0.2	0.7	-0.3	0.3	0.1	-0.5	0.4	-0.6	0.0	0.9	0.5
Diabetes (mother)	4.0	5.1	7.8	-2.3	2.4	2.4	-1.8	-2.5	2.4	-2.8	1.4	2.0
Severe depression (siblings)	0.3	0.4	1.3	0.1	0.2	0.3	0.3	-0.8	1.1	-0.4	-0.9	-0.3
Pack years adult smoking proportion	1.2	1.8	2.9	-1.4	1.3	1.2	-1.3	-1.3	1.1	-1.7	1.5	1.2
Impedance of leg (right)	0.5	2.5	4.4	2.1	-1.9	-1.0	2.1	1.6	-1.1	1.5	-0.2	-1.8
Leg fat-free mass (left)	0.0	0.1	0.2	-0.5	-0.2	-0.2	-0.4	-0.3	-0.2	-0.1	-0.4	0.3
Trunk fat percentage	1.2	4.7	7.6	-2.3	2.2	1.8	-2.7	-2.8	1.9	-2.4	1.1	2.0
Hand grip strength (right)	0.8	2.0	4.0	-1.2	1.2	1.5	-1.3	-2.0	2.0	-1.6	-0.3	0.9
Townsend deprivation index at recruitment	0.1	0.2	0.4	0.3	-0.2	-0.6	0.5	0.3	-0.2	0.3	-0.6	-0.4
Current tobacco smoking	0.3	0.4	1.2	-0.5	0.8	0.4	-0.5	-1.1	1.0	-0.6	0.2	0.2
Average weekly fortified wine intake	0.2	0.2	0.7	0.2	-0.9	0.1	0.1	0.7	-0.7	0.4	0.2	-0.2
Maternal smoking around birth	1.4	2.1	3.3	1.3	-1.3	-1.8	1.4	1.5	-1.5	1.7	-1.1	-1.2
Fed-up feelings	1.3	2.4	4.0	-1.5	2.0	1.3	-1.1	-1.9	1.8	-1.8	0.1	1.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.3	1.5	-0.1	-0.1	0.6	0.0	0.3	-0.8	-0.2	1.2	0.5
Relative age voice broke	0.0	0.1	0.2	0.3	-0.0	0.0	-0.1	-0.0	-0.3	0.4	0.3	-0.2
Taking other prescription medications	1.7	2.6	4.5	1.8	-1.4	-2.1	2.1	1.3	-1.1	1.5	-1.2	-1.6
Age when periods started (menarche)	0.1	0.2	0.6	0.6	-0.6	-0.4	0.7	-0.1	0.3	0.3	-0.3	-0.8
Bilateral oophorectomy (both ovaries removed)	0.4	0.5	1.2	-1.0	0.4	0.6	-0.4	-0.2	-0.4	-0.5	1.0	1.1
Heel bone mineral density (BMD) T-score, automated (left)	1.3	2.9	3.9	-1.8	1.4	1.9	-1.9	-1.6	0.7	-1.6	2.0	1.9
Tinnitus: Yes, but not now, but have in the past	11.8	12.6	16.4	-3.9	3.8	3.5	-3.7	-4.1	3.5	-3.9	1.2	3.5
Qualifications: CSEs or equivalent	0.1	0.2	0.5	-0.6	0.7	-0.2	-0.3	-0.1	-0.2	-0.3	0.1	0.6
Serious illness, injury or assault to yourself	0.1	0.1	0.2	-0.2	0.4	0.0	-0.2	-0.3	-0.3	0.1	0.4	0.2
High blood pressure	1.3	3.7	6.6	-1.9	2.4	1.7	-2.1	-2.6	1.9	-2.0	0.3	1.7
Hayfever, allergic rhinitis or eczema	0.1	0.3	0.5	0.4	-0.7	-0.7	0.7	0.4	-0.2	0.3	-0.5	-0.4
Multivitamins +/- minerals	0.5	0.6	1.3	0.8	-0.6	-1.1	0.8	0.8	-0.2	0.7	-0.7	-0.8
Stomach or abdominal pain in last month	1.0	1.3	2.9	-1.1	1.1	1.2	-1.1	-0.1	-0.8	-0.8	1.7	1.5
Supplements: Glucosamine	0.1	0.1	0.4	-0.1	0.7	0.2	-0.2	-0.1	-0.2	-0.1	0.4	0.3
Diverticular disease/diverticulitis (self-reported)	1.8	2.2	3.1	-1.6	1.4	1.4	-1.4	-1.5	1.6	-1.8	1.0	1.4
Medication: Atenolol	0.6	0.7	1.9	0.8	-0.4	-1.4	0.8	0.3	-0.3	0.8	-1.2	-0.8
Medication: Levothyroxine sodium	0.8	1.3	4.0	1.2	-0.6	-0.9	1.8	-0.0	0.8	0.3	-2.0	-1.3
Sitting height	1.7	11.9	17.8	3.4	-4.2	-3.5	3.3	3.9	-3.5	3.8	-1.5	-3.3
Chronic bronchitis/emphysema (father)	1.2	1.4	3.6	1.2	-1.1	-1.1	1.9	1.0	-0.7	1.1	-1.1	-1.2
High blood pressure (mother)	3.2	4.4	5.6	-2.3	2.3	2.3	-2.2	-1.8	1.3	-2.2	2.0	2.4
Body mass index (BMI)	2.2	9.2	12.9	-3.5	3.4	2.6	-3.6	-3.4	2.1	-3.2	1.5	3.3
Impedance of leg (left)	0.4	1.8	3.3	1.8	-1.6	-0.9	1.6	1.4	-1.0	1.3	-0.2	-1.6
Leg predicted mass (left)	0.0	0.1	0.2	-0.5	-0.3	-0.2	-0.4	-0.3	-0.1	-0.1	-0.4	0.3
Trunk fat mass	0.6	2.7	4.6	-1.8	1.6	1.3	-2.1	-2.1	1.3	-1.8	0.7	1.6
Waist circumference	0.2	0.9	1.6	-1.1	0.8	0.8	-1.2	-1.2	0.6	-1.0	0.5	0.9
Number of incorrect matches in round	0.8	1.3	3.4	0.9	-1.2	-0.7	0.8	1.9	-1.8	1.0	0.8	-0.4
Past tobacco smoking	0.1	0.2	0.6	0.4	-0.7	0.1	0.2	0.2	-0.5	0.3	0.6	-0.4
Alcohol usually taken with meals	0.6	0.9	2.3	1.0	-0.7	-0.8	0.9	0.5	0.8	0.7	-1.5	-1.3
Nervous feelings	0.1	0.2	0.3	-0.4	0.4	0.5	-0.5	-0.3	0.4	-0.5	0.5	0.4
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	1.1	-0.4	-0.2	1.0	-0.2	0.1	-0.3	-0.3	1.0	0.6
Hearing difficulty/problems with background noise	2.0	3.3	5.7	-2.3	2.2	1.2	-1.9	-1.7	0.6	-1.8	1.5	2.4
Hair/balding pattern: Pattern 2	2.0	2.6	4.3	-1.7	1.7	1.6	-2.1	-0.9	0.9	-1.3	1.9	1.9
Had menopause	0.1	0.1	0.3	0.3	0.1	-0.3	0.2	-0.5	0.6	-0.0	-0.4	-0.5
Had other major operations	0.4	0.5	1.6	0.5	0.1	-0.3	0.9	1.3	-1.1	0.3	0.3	-0.1
Forced vital capacity (FVC)	2.3	9.0	14.8	2.7	-3.5	-2.6	3.0	3.9	-3.6	3.3	-1.4	-2.4
Heel bone mineral density (BMD) T-score, automated (right)	1.3	3.1	3.9	-1.9	1.6	1.7	-2.0	-2.0	1.6	-1.9	1.1	1.9
Ever unenthusiastic/disinterested for a whole week	7.2	8.8	13.1	-3.5	3.2	2.1	-3.0	-3.6	3.4	-3.3	-0.1	2.9
Qualifications: None of the above	1.5	3.3	4.6	-2.1	2.1	1.4	-1.9	-1.7	0.4	-1.7	2.1	2.1
Financial difficulties in last 2 years	2.2	2.9	5.3	-1.9	2.1	1.1	-2.3	-1.7	1.6	-1.7	0.6	1.7
Mouth/teeth dental problems	0.4	0.6	1.5	0.9	-0.9	0.5	1.2	-0.0	0.9	0.0	-0.7	-1.0
Heart attack	1.1	1.5	5.6	-0.8	1.1	1.5	-1.2	-0.2	-0.5	-0.6	2.4	1.2
Allergy	0.2	0.5	1.2	-0.5	0.4	0.7	-0.6	-1.1	1.1	-0.5	-0.7	0.1
Pain all over the body in last month	0.1	0.1	0.4	-0.5	-0.1	0.1	-0.3	0.1	0.1	-0.4	0.6	0.4
Diabetes (self-reported)	1.8	2.8	5.4	-1.6	2.1	1.0	-1.8	-2.3	2.0	-1.7	-0.7	1.3
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	1.1	-0.7	0.0	0.8	-0.4	-1.0	0.8	-1.1	0.5	0.6
Medication: Ramipril	0.1	0.2	0.6	0.4	-0.8	-0.2	0.3	0.4	-0.4	0.4	0.2	-0.4
Medication: Simvastatin	0.1	0.2	0.7	0.4	0.1	-0.5	0.2	-0.2	-0.0	0.5	-0.8	-0.5
Fluid intelligence score	1.7	3.6	5.6	1.9	-2.3	-1.8	1.7	1.3	-0.6	2.0	-2.4	-2.2
Illnesses of siblings	1.6	2.3	4.6	1.6	-1.5	-1.5	2.1	1.4	-0.9	1.5	-1.3	-1.5
Neuroticism score	1.5	3.2	4.9	-2.0	2.2	1.6	-1.7	-1.4	1.0	-1.9	1.8	2.1
Weight	0.1	0.3	0.8	-0.9	0.3	0.3	-0.8	-0.9	0.2	-0.6	-0.0	0.6
Impedance of arm (right)	0.3	1.5	3.4	1.6	-1.6	-1.2	1.0	0.7	-0.1	1.2	-1.0	-1.9
Arm fat percentage (right)	2.7	10.7	15.5	-3.6	3.5	2.8	-3.9	-3.9	2.9	-3.5	1.4	3.2
Trunk fat-free mass	0.2	1.3	2.6	0.7	-1.6	-1.1	1.2	1.2	-1.4	1.2	-0.7	-0.7
Hip circumference	0.6	2.7	4.5	-2.0	1.6	1.4	-1.8	-2.1	1.4	-1.8	0.2	1.7
Time employed in main current job	0.1	0.1	0.2	0.2	-0.2	-0.1	0.1	0.3	-0.2	0.4	-0.3	-0.2
Alcohol intake versus 10 years previously	0.4	0.7	1.1	-1.0	1.0	0.8	-0.7	-0.5	0.4	-1.0	0.5	1.1
Father’s age at death	0.3	0.4	1.4	0.4	-0.3	0.2	0.6	-0.8	0.9	-0.1	-1.2	-0.6
Worrier / anxious feelings	1.3	2.4	3.8	-1.7	2.0	1.4	-1.7	-1.2	0.8	-1.4	1.4	1.9
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.4	0.8	-0.8	0.7	0.5	-0.5	-0.3	0.5	-0.9	0.5	0.8
Falls in the last year	0.8	1.1	2.2	-1.2	0.8	0.5	-1.5	-1.0	-0.0	-0.9	1.4	1.2
Hair/balding pattern: Pattern 3	0.5	0.8	2.4	-0.7	1.5	0.5	-0.5	-1.3	0.7	-0.9	-0.4	0.7
Number of live births	0.7	1.0	4.5	-0.4	0.7	0.5	-0.7	0.5	-1.4	0.1	2.1	1.0
Forced expiratory volume in 1-second (FEV1)	1.2	4.0	8.9	1.5	-2.2	-1.6	1.7	2.7	-3.0	2.2	-0.9	-1.2
Pulse rate	0.1	0.2	0.6	-0.1	-0.2	-0.2	0.5	0.6	-0.8	0.2	0.5	0.1
Happiness	1.6	1.9	3.0	-1.6	1.5	1.1	-1.1	-1.5	1.6	-1.7	0.6	1.4
Noisy workplace	1.2	1.5	2.7	-1.4	1.2	1.4	-1.5	-1.6	0.9	-1.0	-0.0	1.3
Qualifications: A levels/AS levels or equivalent	4.4	9.8	18.8	3.5	-2.8	-3.5	2.8	2.0	-0.1	3.0	-4.3	-4.0
Serious illness, injury or assault of a close relative in last 2 years	0.7	0.8	5.1	0.6	-0.2	-0.6	0.1	0.1	0.7	0.3	-2.3	-0.7
Mouth/teeth dental problems: Dentures	0.6	1.1	4.3	0.1	0.1	-1.6	-0.5	0.9	-2.1	1.2	0.6	0.2
Asthma	0.1	0.2	0.9	0.1	0.3	0.8	0.1	-0.1	0.3	-0.5	0.9	0.3
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.6	1.9	-0.7	0.3	0.9	-0.3	0.2	-0.4	-0.7	1.4	1.1
Medication: Cholesterol lowering	0.2	0.3	0.7	0.7	-0.3	-0.4	0.6	-0.1	0.3	0.3	-0.7	-0.8
Depression (self-reported)	0.4	0.5	1.1	-0.6	0.8	0.5	-0.2	-1.0	0.9	-1.0	-0.0	0.6
Medication: Lansoprazole	3.1	3.5	5.7	-2.1	2.4	1.4	-2.1	-1.5	0.5	-2.0	2.0	2.2
Prospective memory result	0.3	0.4	1.4	-0.3	0.4	0.7	-0.7	-0.1	-0.9	-0.3	1.2	0.6
Lung cancer (father)	3.0	3.5	5.3	1.8	-1.7	-2.3	2.0	1.9	-1.4	2.1	-1.5	-1.9
Illnesses of mother	1.4	1.7	2.8	1.1	-1.5	-1.5	0.9	1.6	-1.7	1.4	-0.5	-1.0
Forced expiratory volume in 1-second (FEV1), Best measure	1.1	3.6	6.1	1.4	-2.2	-1.7	1.7	2.5	-2.4	2.1	-1.1	-1.3
Pulse wave Arterial Stiffness index	1.4	1.7	2.4	1.5	-1.3	-1.5	1.5	1.0	-1.0	1.3	-0.7	-1.5
Impedance of arm (left)	0.5	2.5	5.0	2.0	-1.8	-1.7	1.5	1.1	-0.2	1.5	-1.4	-2.2
Arm fat mass (right)	1.5	6.1	9.2	-2.9	2.5	2.1	-3.0	-2.9	1.8	-2.7	1.2	2.6
Trunk predicted mass	0.2	1.4	2.8	0.7	-1.7	-1.1	1.2	1.3	-1.5	1.2	-0.7	-0.7
Standing height	2.5	24.9	39.6	5.1	-6.3	-4.8	5.4	5.0	-4.1	5.2	-3.1	-5.2
Length of working week for main job	1.9	2.0	3.1	1.6	-1.6	-1.4	1.4	1.3	-1.2	1.7	-0.9	-1.7
Exposure to tobacco smoke at home	1.2	1.3	2.2	1.0	-1.3	-0.9	1.2	1.3	-1.3	1.5	-0.4	-0.9
Breastfed as a baby	2.5	3.1	4.5	1.8	-2.1	-1.5	1.7	1.7	-1.3	2.0	-1.4	-2.0
Tense / ‘highly strung’	1.9	3.2	5.3	-2.2	2.2	1.3	-2.0	-1.4	0.5	-1.7	2.0	2.3
Seen doctor (GP) for nerves, anxiety, tension or depression	2.0	3.1	5.3	-1.8	2.3	1.4	-1.8	-2.1	1.6	-2.0	0.5	1.8
Hair/balding pattern: Pattern 4	0.4	1.0	2.7	1.0	-0.5	-1.0	1.0	-0.4	1.0	0.3	-1.6	-1.3
Birth weight of first child	1.0	1.9	4.2	-1.8	1.2	1.3	-2.1	-0.9	0.5	-1.2	1.0	1.7
Peak expiratory flow (PEF)	0.2	0.5	2.8	0.0	-0.7	-0.0	0.3	0.9	-1.7	0.5	0.4	0.2
Pulse wave reflection index	1.2	1.5	3.1	1.5	-1.1	-1.3	1.1	0.3	0.1	1.0	-1.8	-1.6
Ever highly irritable/argumentative for 2 days	0.9	1.1	2.1	-1.4	1.0	0.8	-0.7	-1.2	0.8	-1.2	0.4	1.4
Loud music exposure frequency	3.6	4.0	7.1	-2.7	1.7	2.0	-2.1	-1.6	1.5	-2.2	1.2	2.4
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	1.5	0.4	-0.2	0.1	0.1	-0.2	1.0	-0.1	-1.2	-0.5
Mouth/teeth dental problems: Bleeding gums	3.3	4.3	6.0	-2.3	2.3	1.8	-2.2	-2.2	2.1	-2.5	0.7	2.1
Blood clot in the leg (DVT)	1.4	1.8	6.1	0.5	-0.6	-0.0	-0.0	1.6	-2.3	1.1	2.5	0.1
Medication: Paracetamol	0.3	0.5	1.6	-0.5	0.6	0.5	-0.6	0.1	-0.6	-0.5	1.3	0.8
Headache pain in last month	0.9	1.5	5.3	-0.9	0.7	0.9	-0.4	-1.5	2.3	-1.6	-0.9	0.4
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	1.5	-0.2	-0.3	-0.2	0.1	1.2	-1.2	0.3	1.0	0.6
Glaucoma (self-reported)	0.4	0.5	0.8	0.9	-0.5	-0.6	0.4	0.6	-0.8	0.9	-0.7	-0.7
Gout (self-reported)	0.2	0.3	0.8	0.1	-0.4	0.0	0.6	-0.7	0.9	-0.2	-0.8	-0.4
Hypothyroidism/myxoedema (self-reported)	0.6	1.2	4.3	0.4	0.0	-0.3	1.1	-0.8	1.8	-0.5	-2.1	-0.7
Medication: Amlodipine	0.2	0.3	0.6	0.4	-0.2	-0.8	0.3	0.2	-0.7	0.6	-0.5	-0.5
Medication: Ventolin 100micrograms inhaler	0.2	0.2	0.7	0.3	-0.8	0.0	0.9	-0.1	0.5	0.1	0.0	-0.6
Birth weight	0.5	1.1	3.8	0.3	-0.5	-1.1	0.7	1.8	-1.9	1.0	-0.2	-0.1
Chronic bronchitis/emphysema (mother)	1.5	1.7	2.8	1.5	-0.7	-1.7	1.6	1.3	-1.1	1.4	-0.5	-1.5
High blood pressure (siblings)	2.4	3.5	6.1	-1.9	1.9	2.3	-2.5	-1.6	1.1	-1.9	1.4	1.9
Forced vital capacity (FVC), Best measure	2.1	7.6	12.7	2.4	-3.3	-2.6	2.6	3.6	-3.1	3.0	-1.2	-2.3
Body fat percentage	1.8	7.2	10.4	-2.8	2.9	2.3	-3.2	-3.2	2.4	-3.0	1.3	2.5
Leg fat percentage (right)	2.5	9.0	12.5	-3.1	3.1	3.1	-3.2	-3.5	2.7	-3.4	1.5	2.9
Arm fat-free mass (right)	0.1	0.6	2.0	0.2	-1.0	-0.6	0.5	1.0	-1.4	0.7	-0.0	-0.1
Exposure to tobacco smoke outside home	3.1	4.2	7.0	-2.5	2.5	1.8	-2.5	-1.6	0.5	-1.6	1.8	2.6
Comparative body size at age 10	0.4	1.0	2.3	-1.0	1.4	0.1	-1.5	-1.1	0.9	-0.5	-1.0	0.6
Number of full brothers	1.2	1.5	3.2	-1.7	1.4	0.8	-1.8	-0.9	0.3	-0.9	0.7	1.5
Worry too long after embarrassment	0.1	0.2	0.4	-0.6	0.7	0.1	-0.4	-0.3	0.2	-0.3	0.7	0.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.1	0.2	0.5	-0.2	0.0	0.3	-0.3	-0.7	0.5	-0.2	-0.6	-0.0
Wheeze or whistling in the chest in last year	0.7	1.2	5.6	-0.7	0.7	0.9	-0.8	0.6	-1.0	-0.1	2.4	1.1
Number of children fathered	0.1	0.1	0.3	-0.0	0.2	0.5	-0.4	0.1	-0.5	0.3	0.3	0.2
Reason for reducing amount of alcohol drunk: Health precaution	1.2	1.4	4.6	0.4	-0.6	0.1	0.0	1.9	-2.1	0.7	1.8	0.3
Age at first live birth	1.9	3.4	7.0	1.9	-1.2	-2.5	1.5	0.7	0.2	1.8	-2.6	-2.3
Pulse wave peak to peak time	0.6	0.7	1.1	-1.1	0.8	1.0	-1.0	-0.6	0.7	-0.9	0.4	1.0
Health satisfaction	0.3	0.5	0.8	-0.9	0.8	0.5	-0.5	-0.3	0.4	-0.9	0.6	0.9
Shortness of breath walking on level ground	0.3	0.3	0.9	-0.1	0.6	0.7	0.5	-0.5	0.9	-0.7	0.4	0.0
Qualifications: College or University degree	3.2	10.2	15.8	3.6	-3.9	-3.3	3.4	2.1	-0.9	3.1	-3.3	-4.0
Eye problems/disorders: None of the above	0.1	0.2	0.6	0.2	0.5	0.1	-0.1	-0.4	0.7	-0.0	-0.8	-0.3
Mouth/teeth dental problems: Loose teeth	1.2	1.4	2.4	-1.4	1.1	0.9	-1.2	-0.9	0.2	-1.3	1.5	1.5
Emphysema/chronic bronchitis	0.1	0.1	0.3	-0.0	0.2	-0.4	0.5	0.4	-0.2	0.0	0.5	0.1
Medication for pain relief, constipation, heartburn	1.6	2.7	6.8	1.7	-1.6	-1.4	1.6	0.4	0.7	1.2	-2.6	-2.3
Neck or shoulder pain in last month	1.7	2.5	4.3	-1.9	1.8	1.3	-1.7	-1.1	0.2	-1.4	1.8	2.1
Medication: Blood pressure	1.0	1.7	4.5	-1.1	1.2	1.2	-1.2	-2.1	1.8	-1.4	-0.2	0.7
Angina (self-reported)	1.7	2.2	5.9	-1.5	1.6	0.8	-1.9	0.1	-0.7	-0.7	2.4	2.0
Migraine (self-reported)	0.5	0.6	2.0	0.6	-0.1	-0.4	0.5	-0.4	1.4	-0.1	-1.4	-1.0
Medication: Ibuprofen	0.2	0.2	0.5	-0.0	-0.5	0.3	0.6	0.6	-0.5	-0.2	0.7	0.2
Medication: Allopurinol	0.6	0.8	1.5	1.0	-1.2	-0.7	1.2	0.8	-0.2	0.9	-0.9	-1.1
Medication: Omeprazole	0.3	0.4	1.0	0.3	-0.4	-1.0	0.6	0.8	-0.8	0.7	0.0	-0.3
Medication: Seretide 50 evohaler	0.7	0.8	2.2	0.6	-1.5	-0.9	1.0	0.9	-0.6	0.9	-0.2	-0.9
Mean time to correctly identify matches	1.1	2.2	3.6	-1.7	1.5	0.9	-1.8	-1.9	1.4	-1.4	0.5	1.6
Heart disease (mother)	1.2	1.4	2.6	-1.4	1.6	1.4	-1.3	-0.6	0.6	-1.1	0.8	1.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.4	1.1	-0.7	0.5	0.7	-1.0	-0.0	-0.1	-0.2	0.7	0.7
Whole body fat mass	1.2	4.9	7.4	-2.5	2.2	1.9	-2.7	-2.7	1.8	-2.4	1.0	2.2
Leg fat mass (right)	1.4	5.4	7.6	-2.5	2.5	2.1	-2.7	-2.8	1.8	-2.6	1.1	2.4
Arm predicted mass (right)	0.1	0.4	1.5	-0.0	-0.8	-0.4	0.3	0.8	-1.2	0.5	0.2	0.1
Pulse rate, automated reading	0.0	0.0	0.2	-0.3	0.3	0.1	0.1	-0.2	-0.0	-0.2	0.4	0.1
Alcohol intake frequency.	1.9	4.3	7.6	-2.8	2.5	1.6	-2.2	-1.7	1.0	-2.2	1.6	2.7
Comparative height size at age 10	1.9	10.3	14.7	2.9	-3.8	-3.3	3.2	3.6	-3.5	3.6	-1.6	-2.9
Number of full sisters	1.5	1.8	3.5	-1.4	1.9	0.8	-1.8	0.2	-0.7	-0.8	1.8	1.7
Suffer from ‘nerves’	0.4	0.6	2.9	-0.7	0.5	0.5	-0.6	-0.2	-0.2	-0.6	1.7	0.7
Overall health rating	1.0	2.0	4.9	-1.6	1.4	1.1	-1.3	-0.9	-0.2	-1.3	2.2	1.8
Chest pain or discomfort	2.3	3.3	5.5	-2.1	1.7	2.0	-1.8	-1.0	0.3	-1.8	2.3	2.3
Had major operations	1.6	1.9	4.3	-1.3	1.4	1.1	-1.4	-2.1	1.6	-1.5	0.5	1.0
Age at last live birth	1.2	1.8	5.5	1.2	-0.4	-2.3	0.9	0.4	-0.1	1.4	-1.9	-1.5
Family relationship satisfaction	0.9	1.1	1.8	-1.3	1.3	0.6	-1.2	-0.7	0.3	-1.0	1.1	1.3
Leg pain on walking	0.6	0.8	3.7	-0.6	0.7	0.8	-0.6	0.4	-0.8	-0.3	1.9	0.8
Qualifications: NVQ or HND or HNC or equivalent	1.5	1.8	3.3	-1.4	1.5	1.8	-1.5	-0.5	0.2	-1.1	1.5	1.7
Commuting to job workplace: Car/motor vehicle	2.5	2.8	7.7	-1.4	1.0	1.7	-1.2	-2.3	2.8	-1.9	-0.7	0.9
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	0.9	0.3	-1.0	-0.3	0.8	0.4	-0.9	0.5	0.9	-0.3
Medication: Aspirin	0.1	0.1	0.3	0.0	0.1	-0.5	-0.1	0.4	-0.6	0.4	-0.3	0.1
Supplements: Vitamin C	0.5	0.6	1.0	-1.0	0.9	0.1	-0.8	-0.5	0.7	-0.4	-1.0	0.9
Knee pain experienced in last month	1.8	2.8	5.1	-1.9	2.3	1.5	-2.1	-0.9	-0.1	-1.1	1.6	2.2
Hypertension (Self-reported)	1.2	3.4	6.6	-1.8	2.3	1.5	-1.9	-2.6	1.9	-1.8	-0.1	1.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.7	2.0	3.0	-1.6	1.6	1.1	-1.7	-1.0	0.6	-1.4	1.4	1.7
Illnesses of father: Heart disease	1.4	2.0	3.5	-1.3	1.4	1.8	-1.8	-0.7	-0.2	-1.1	1.7	1.9
Illnesses of siblings: Diabetes	1.0	1.3	2.4	1.2	-0.9	-1.6	1.2	1.1	-1.3	1.2	-0.4	-1.1
Smoking status: Previous	0.3	0.4	0.9	0.6	-0.3	-0.8	0.6	0.8	-0.4	0.6	-0.9	-0.4
Forced expiratory volume in 1-second (FEV1), predicted	1.0	2.0	3.6	1.0	-1.8	-1.6	1.1	1.9	-1.8	1.6	-0.3	-0.9
Whole body fat-free mass	0.1	0.5	1.2	0.2	-1.1	-0.7	0.5	0.7	-1.1	0.7	-0.4	-0.3
Leg fat-free mass (right)	0.0	0.1	0.2	-0.4	-0.3	-0.3	-0.4	-0.1	-0.3	0.0	-0.4	0.2
Arm fat percentage (left)	2.6	10.3	14.8	-3.5	3.5	2.7	-3.9	-3.8	2.9	-3.5	1.3	3.1
Average weekly red wine intake	0.2	0.2	1.4	0.5	0.1	-0.2	0.1	-0.2	0.3	0.2	-1.2	-0.4
Handedness (chirality/laterality): Left-handed	0.9	1.1	5.2	-0.5	0.5	0.7	-1.0	0.6	-1.1	-0.1	2.3	1.0
Mood swings	1.7	3.0	5.0	-1.9	2.2	1.8	-1.6	-1.4	1.1	-2.0	1.1	2.1
Loneliness, isolation	1.3	1.8	2.6	-1.5	1.6	1.0	-1.6	-1.1	0.4	-1.4	1.5	1.6
Long-standing illness, disability or infirmity	0.1	0.1	0.2	-0.3	0.5	-0.3	0.1	-0.3	-0.0	-0.2	-0.1	0.4
Ever had bowel cancer screening	0.3	0.4	1.7	-0.3	0.3	0.7	-0.7	0.3	-0.3	-0.3	1.3	0.6
Diabetes diagnosed by doctor	1.2	1.9	3.4	-1.4	1.9	0.7	-1.6	-1.9	1.4	-1.3	-0.3	1.3
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	0.6	0.3	0.1	-0.4	0.2	0.8	-0.6	0.4	0.3	-0.2
Friendships satisfaction	1.2	1.5	3.3	-1.1	1.2	0.6	-1.4	-1.6	1.8	-1.3	-0.3	0.8
Qualifications: nursing, teaching	0.7	1.1	3.2	0.9	-1.3	-0.8	0.7	0.1	0.4	1.1	-1.8	-1.4
Commuting to job workplace: Walk	2.2	2.3	4.0	1.5	-1.6	-2.0	1.5	1.3	-0.8	1.6	-1.5	-1.7
Eye problems/disorders: Cataract	0.6	0.7	1.6	0.6	-0.7	-0.8	0.9	1.1	-1.3	0.5	0.9	-0.1
Mouth/teeth dental problems: Mouth ulcers	0.0	0.1	0.2	-0.4	0.4	-0.3	-0.0	0.0	-0.0	-0.1	-0.2	0.4
Medication for cholesterol	0.3	0.5	1.2	0.6	-1.1	-0.4	0.6	0.9	-0.7	0.7	0.1	-0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.7	3.6	-0.2	-0.3	0.0	-0.1	0.6	-1.4	0.2	1.9	0.3
Back pain experienced in last month	1.7	2.5	4.7	-1.8	1.6	2.2	-1.4	-0.9	0.3	-1.5	1.7	2.1
Mineral and other dietary supplements	0.2	0.3	0.6	-0.5	0.2	0.7	-0.5	-0.4	0.4	-0.6	0.8	0.4
Breast cancer (self-reported)	0.5	0.6	2.1	-0.1	-0.3	0.5	0.1	1.1	-1.1	0.3	1.5	0.2
Asthma (self-reported)	0.1	0.2	0.8	0.4	-0.0	0.6	0.4	0.1	0.0	-0.2	0.9	0.0
Osteoporosis (self-reported)	2.0	2.5	3.8	1.9	-1.5	-1.7	1.9	1.1	-0.9	1.7	-1.4	-1.8
Osteoarthritis (self-reported)	0.9	1.2	4.4	0.8	-0.5	-1.2	0.5	1.4	-2.1	1.4	0.3	-0.3
Medication: Aspirin	0.1	0.2	0.5	-0.5	0.7	-0.0	-0.7	-0.2	-0.4	-0.0	0.0	0.6
Medication: Gliclazide	0.5	0.5	1.3	-0.6	0.6	0.9	-0.4	-1.1	1.0	-0.7	0.0	0.5
Illnesses of father: None of the above (group 1)	0.9	1.2	4.3	0.5	-0.6	-1.0	1.0	-0.4	1.4	0.2	-2.1	-1.2
Smoking status: Current	0.6	0.9	1.8	-0.9	1.2	0.7	-0.9	-1.3	1.1	-0.9	0.5	0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.3	2.8	7.0	1.2	-1.2	-1.9	1.2	2.3	-2.6	1.9	-0.7	-0.9
Whole body water mass	0.1	0.5	1.2	0.2	-1.1	-0.7	0.5	0.7	-1.1	0.7	-0.4	-0.2
Leg predicted mass (right)	0.0	0.1	0.2	-0.4	-0.3	-0.3	-0.4	-0.1	-0.3	0.1	-0.4	0.2
Arm fat mass (left)	1.4	5.9	8.9	-2.8	2.5	2.0	-3.0	-2.8	1.7	-2.6	1.2	2.6
Number of self-reported non-cancer illnesses	0.2	0.3	1.4	0.1	0.3	-0.5	0.3	-0.9	0.5	-0.2	-1.2	-0.2
Average weekly champagne plus white wine intake	0.6	0.8	1.6	1.0	-0.7	-1.2	0.5	0.8	-0.6	1.2	-0.8	-1.0
Miserableness	2.5	4.3	6.6	-1.9	2.6	1.8	-2.0	-2.4	2.5	-2.4	-0.0	1.8
Guilty feelings	0.4	0.6	2.2	-0.4	0.6	0.5	-0.4	0.7	-1.0	0.0	1.5	0.9
Wears glasses or contact lenses	0.1	0.1	0.3	0.5	-0.1	-0.2	0.3	0.3	0.4	0.0	-0.4	-0.6
Ever taken oral contraceptive pill	2.6	2.9	7.6	1.9	-1.3	-1.7	2.1	0.6	0.3	1.2	-2.8	-2.0
Hearing aid user	0.5	0.6	1.4	0.7	-0.6	-0.5	1.0	1.2	-1.1	0.5	0.3	-0.5
Mother’s age at death	0.7	0.9	4.3	-0.2	0.1	0.6	-0.0	-1.2	2.1	-1.0	-0.7	-0.1
Financial situation satisfaction	1.1	1.4	2.3	-1.5	1.3	0.5	-1.5	-1.2	1.1	-1.1	0.6	1.3
Tinnitus: Yes, now most or all of the time	0.0	0.0	0.2	0.2	0.1	-0.2	0.4	0.2	-0.2	-0.0	0.2	0.1
Commuting to job workplace: Public transport	4.3	5.1	8.7	2.4	-2.3	-3.0	2.2	2.1	-1.4	2.3	-1.9	-2.5
Eye problems/disorders: Glaucoma	0.1	0.1	0.5	0.5	-0.2	-0.1	0.0	0.2	-0.2	0.4	-0.7	-0.4
Medication: Blood pressure	0.3	0.6	1.5	-0.8	1.2	0.5	-1.0	-1.0	0.7	-0.6	-0.0	0.8
Pain type(s) experienced in last month: Hip pain	1.3	1.6	2.3	-1.4	1.0	1.1	-1.5	-1.5	1.5	-1.3	-0.1	1.2
Supplements: Fish oil (including cod liver oil)	0.5	0.6	1.2	0.7	-0.4	-1.1	0.3	0.7	-0.9	1.0	-1.1	-0.6
High cholesterol (Self-reported)	0.2	0.4	1.0	0.1	0.9	0.0	0.0	-1.0	0.9	-0.4	-0.8	-0.2
Medication: Bendroflumethiazide	2.4	3.7	5.9	-2.0	2.2	1.4	-2.4	-2.4	2.0	-1.9	0.9	1.6
Medication: Paracetamol	0.0	0.0	0.1	-0.0	0.2	-0.0	-0.1	0.1	-0.1	-0.3	0.4	0.2
Medication: Lisinopril	1.7	2.2	5.1	1.5	-1.0	-1.9	1.3	0.7	-0.3	1.5	-2.3	-1.7
Medication: Atorvastatin	0.0	0.0	0.1	0.4	0.2	-0.1	0.0	0.0	0.1	0.2	-0.2	-0.3
Illnesses of father: High blood pressure	1.3	1.7	3.1	-1.1	1.5	1.5	-1.6	-0.7	0.2	-1.1	1.8	1.3
Alcohol drinker status: Never	0.2	0.2	0.9	-0.1	0.3	-0.1	-0.0	0.6	-1.0	0.5	0.6	0.3
Ever smoked	0.2	0.4	1.1	-0.6	1.1	0.1	-0.4	-0.6	1.0	-0.7	-0.4	0.5
Basal metabolic rate	0.0	0.1	0.5	-0.2	-0.6	-0.3	0.1	0.2	-0.7	0.2	-0.2	0.1
Leg fat percentage (left)	2.7	9.7	13.4	-3.2	3.4	3.0	-3.5	-3.7	2.9	-3.5	1.4	3.0
Arm fat-free mass (left)	0.1	0.3	1.3	0.0	-0.9	-0.3	0.4	0.7	-1.1	0.4	0.3	0.1
Number of operations (self-reported)	0.2	0.3	1.3	-0.2	0.5	0.1	-0.3	0.4	-0.6	-0.0	1.1	0.4
Average weekly beer plus cider intake	1.2	1.8	3.7	-1.8	0.8	1.4	-1.1	-1.0	0.1	-1.4	1.5	1.9
Irritability	0.3	0.5	1.4	-0.7	1.2	0.6	-0.6	-0.4	0.5	-0.8	0.6	0.8
Risk taking	0.3	0.4	1.0	-0.7	0.5	0.6	-0.8	0.1	-0.4	-0.3	1.0	0.7
Ever had prostate specific antigen (PSA) test	0.3	0.3	0.8	0.5	-0.8	-0.0	0.5	0.9	-0.6	0.4	0.3	-0.4
Fractured/broken bones in last 5 years	0.4	0.5	1.9	0.6	-0.4	-1.4	0.3	0.8	-0.7	0.7	-0.3	-0.6
Age started oral contraceptive pill	7.3	9.1	13.1	3.2	-3.3	-3.6	3.2	2.8	-1.4	3.0	-2.5	-3.5
Diastolic blood pressure, automated reading	0.8	2.4	4.3	-1.3	1.9	1.7	-2.1	-1.3	0.6	-1.5	1.7	1.6
Ever depressed for a whole week	1.1	1.4	2.3	-1.2	1.5	1.1	-1.0	-1.2	1.3	-1.4	0.6	1.1
Unable to work because of sickness or disability	0.4	0.5	1.7	-0.6	0.5	0.6	-0.4	-0.3	-0.2	-0.5	1.3	0.9
Commuting to job workplace: Cycle	0.9	1.1	2.2	1.0	-0.8	-1.4	0.7	0.9	-0.3	1.2	-1.5	-1.2
Myopia	0.9	1.4	2.7	1.6	-1.3	-0.9	1.3	1.0	-0.8	1.2	-0.3	-1.4
Vascular/heart problems diagnosed by doctor	1.1	2.9	5.2	1.7	-2.2	-1.4	2.1	2.3	-1.5	1.6	-0.4	-1.5
Cholesterol lowering medication	0.1	0.1	0.6	0.0	0.5	0.1	-0.2	-0.4	0.4	-0.0	-0.8	-0.1
Medication: Omeprazole (e.g. Zanprol)	0.5	0.7	2.2	0.3	-0.3	-1.0	0.6	1.2	-1.5	0.8	0.5	-0.0
Pain experienced in last month	4.0	6.7	9.5	3.0	-2.9	-2.9	2.6	2.2	-1.5	2.8	-1.6	-3.1
Supplements: Calcium	7.3	8.1	12.2	3.1	-2.7	-3.5	3.0	2.7	-2.3	3.1	-2.0	-2.9
Basal cell carcinoma (self-reported)	2.2	2.6	5.1	1.8	-1.5	-1.6	1.6	1.3	-0.5	1.6	-2.3	-1.9
Heart attack/myocardial infarction (self-reported)	1.4	1.7	5.0	-1.1	1.4	1.6	-1.4	-0.5	-0.1	-0.9	2.2	1.4
Deep venous thrombosis (DVT) (self-reported)	1.3	1.7	5.2	0.6	-0.7	-0.2	0.1	1.6	-2.2	1.2	2.3	0.0
Heart disease (siblings)	0.9	1.2	2.7	-1.3	1.4	0.3	-1.6	-0.3	-0.5	-0.3	1.2	1.5
Alcohol drinker status: Previous	3.5	4.0	7.1	-2.6	2.1	1.4	-2.4	-1.7	0.6	-1.8	1.9	2.7
Pack years of smoking	0.9	1.3	2.1	-1.2	1.1	0.9	-1.1	-1.1	0.9	-1.4	1.4	1.0
Impedance of whole body	0.6	3.3	5.4	2.3	-2.2	-1.5	2.0	1.7	-0.9	1.8	-0.8	-2.3
Leg fat mass (left)	1.5	5.7	8.1	-2.6	2.6	2.1	-2.9	-2.8	1.8	-2.6	1.1	2.5
Arm predicted mass (left)	0.1	0.3	1.4	-0.1	-0.7	-0.2	0.2	0.6	-1.2	0.3	0.3	0.2