TWAS hub - GOLM1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1020	0.0320	5.3e-06	0.025	0.059	0.031	0.060	0.030	4.0e-04	1.1e-07	1.1e-04	8.1e-08	1.2e-04
2	GTEx	Artery Aorta	0.1680	0.0690	6.3e-03	-0.001	NA	0.076	NA	0.029	3.6e-01	NA	5.2e-05	NA	9.9e-03
3	GTEx	Muscle Skeletal	0.0710	0.0275	1.7e-03	-0.002	NA	0.027	NA	0.005	6.5e-01	NA	1.0e-03	NA	9.7e-02
4	GTEx	Nerve Tibial	0.2353	0.0762	7.4e-03	0.061	NA	0.030	NA	0.050	4.0e-05	NA	3.2e-03	NA	2.0e-04
5	GTEx	Skin Sun Exposed Lower leg	0.2180	0.0700	5.0e-04	0.038	NA	0.036	NA	0.067	3.8e-04	NA	5.7e-04	NA	3.1e-06
6	GTEx	Thyroid	0.6360	0.0470	0.0e+00	0.488	NA	0.540	NA	0.455	4.1e-42	NA	1.8e-48	NA	2.7e-38
7	GTEx	Whole Blood	0.4160	0.0610	5.1e-09	0.162	NA	0.146	NA	0.164	8.6e-15	NA	2.0e-13	NA	6.2e-15
8	METSIM	Adipose	0.0711	0.0270	1.6e-04	0.021	0.029	0.034	0.035	0.024	3.5e-04	2.8e-05	5.7e-06	5.1e-06	1.5e-04
9	NTR	Blood	0.0808	0.0202	3.0e-11	0.048	0.043	0.056	0.048	0.053	4.1e-15	8.6e-14	1.2e-17	3.6e-15	1.1e-16
10	YFS	Blood	0.0789	0.0233	1.6e-08	0.038	0.026	0.041	0.047	0.047	1.7e-12	4.2e-09	2.4e-13	3.8e-15	4.0e-15
11	TCGA	Thyroid Carcinoma	0.1890	0.0710	5.7e-05	0.109	0.075	0.101	NA	0.102	9.2e-11	9.1e-08	4.4e-10	NA	4.2e-10

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
Alcohol drinker status: Previous	4.7	5.3	15.1	0.1	2.5	0.3	3.3	3.9	-1.7	3.5	-0.6	1.9	2.4	-1.3
Ever had prostate specific antigen (PSA) test	3.2	3.7	7.7	-0.9	2.7	1.6	1.5	0.7	-2.8	1.9	0.8	2.3	1.7	-2.7
Ever used hormone-replacement therapy (HRT)	2.9	3.7	7.2	0.9	-2.2	-0.4	-2.2	-1.6	2.7	-2.4	0.8	-1.6	-2.2	2.5
Medication: Ibuprofen (e.g. Nurofen)	2.6	3.3	12.6	-0.2	3.0	3.6	1.6	2.5	0.8	1.1	1.4	0.6	0.6	1.1
Medication: Ibuprofen	2.6	3.2	11.7	0.1	2.8	3.4	1.4	2.3	0.1	1.4	2.0	1.0	0.9	0.4
Supplements: Fish oil (including cod liver oil)	2.6	3.4	9.2	2.7	1.0	-0.3	1.6	0.2	0.9	1.8	1.7	2.8	3.0	1.4
Mineral and other dietary supplements	2.5	3.4	10.2	-2.6	-1.3	1.0	-1.9	-0.6	-0.3	-2.1	-1.3	-2.6	-3.2	-0.9
Had menopause	2.2	2.8	5.6	0.8	-1.6	-1.7	-1.6	-1.2	2.0	-2.4	-1.4	-1.7	-1.7	1.7
Commuting to job workplace: Walk	2.2	2.4	4.9	1.4	-1.4	-1.5	-1.5	-1.9	2.2	-1.9	-0.2	-1.2	-0.5	2.1
Mouth/teeth dental problems: Bleeding gums	2.1	2.7	6.8	-0.8	1.6	0.3	2.6	2.6	-0.8	2.6	-1.9	1.1	1.0	-0.5
Illnesses of father: None of the above (group 1)	2.0	2.4	5.2	-0.0	1.3	1.2	0.9	1.1	-2.3	1.8	0.6	2.2	1.8	-2.1
High blood pressure (siblings)	1.8	2.6	6.4	0.9	-1.8	-2.5	-1.2	-1.9	1.6	-1.7	-0.9	-1.7	-1.3	1.4
Medication: Seretide 50 evohaler	1.8	2.0	8.0	-1.8	-1.1	-1.0	-0.2	-1.1	0.0	-1.2	-1.4	-2.0	-2.8	-0.3
Multivitamins +/- minerals	1.7	2.1	4.9	1.5	2.1	1.0	0.7	1.7	-0.9	1.2	1.4	1.7	2.2	-0.5
Supplements: Glucosamine	1.7	2.2	6.1	0.3	2.4	0.6	1.1	1.1	-0.1	1.5	1.3	2.2	2.5	0.3
Commuting to job workplace: Car/motor vehicle	1.7	2.0	6.7	-1.0	2.6	1.4	1.6	2.5	-0.0	1.8	0.1	0.5	0.6	0.1
High blood pressure (mother)	1.6	2.2	8.7	-0.5	-1.2	-1.2	-1.6	-3.0	0.0	-2.0	-1.8	-0.9	-1.3	-0.4
Hearing difficulty/problems with background noise	1.6	2.6	11.1	-0.5	-0.4	0.2	-0.3	1.0	-3.3	0.5	-0.5	1.6	1.1	-3.3
Depression (self-reported)	1.6	2.0	8.2	0.7	-0.2	-0.2	0.8	-0.4	2.9	-0.9	-0.6	-1.1	-1.5	2.7
Prospective memory result	1.6	2.0	4.7	-1.3	1.2	2.1	-1.2	-0.1	0.5	-2.0	-0.3	-1.9	-2.2	0.1
Forced expiratory volume in 1-second (FEV1), predicted	1.6	3.4	14.4	0.0	3.8	2.5	1.9	1.0	-0.4	2.0	1.7	1.5	1.8	-0.1
Commuting to job workplace: Cycle	1.6	2.0	5.0	0.3	-2.1	-2.2	-0.1	0.3	-1.8	0.0	-1.9	-0.8	-1.0	-1.9
Angina	1.5	2.0	5.0	-2.0	-1.1	0.7	-1.1	-0.1	-1.6	-0.7	-1.1	-1.4	-2.2	-1.9
Frequency of unenthusiasm / disinterest in last 2 weeks	1.5	1.9	6.5	0.8	1.9	0.9	2.5	1.7	-1.1	1.8	-0.2	0.9	1.0	-0.9
Taking other prescription medications	1.5	2.4	6.9	-1.0	-1.2	-1.3	-1.2	-0.7	-0.9	-1.7	-1.9	-2.1	-2.6	-1.3
Fluid intelligence score	1.5	3.0	7.7	0.5	0.5	-0.4	1.6	1.1	-2.2	2.8	1.7	2.3	2.1	-1.9
Exposure to tobacco smoke outside home	1.5	2.0	4.8	-2.2	0.7	0.7	1.0	1.9	0.9	-0.3	-1.9	-2.0	-1.5	0.7
Medication: Aspirin	1.5	1.9	5.3	-0.8	-2.0	-0.8	-2.3	-1.5	-0.3	-1.8	0.0	-0.9	-2.0	-0.6
Osteoporosis (self-reported)	1.5	1.9	4.2	1.8	1.3	1.1	1.3	0.2	-0.3	1.3	1.7	2.0	2.0	0.0
Medication: Aspirin	1.5	1.9	6.0	-0.5	-2.0	-0.4	-2.4	-1.6	-0.1	-2.0	0.5	-0.6	-1.8	-0.4
Depression (Nagel 2018)	1.4	2.2	3.9	-0.4	1.9	1.5	2.0	1.9	-1.7	1.6	0.5	0.9	1.2	-1.5
Crohns Disease (2017)	1.4	3.2	11.5	0.6	0.7	3.4	1.4	1.8	2.4	0.7	1.9	-0.0	0.9	2.6
Illnesses of father: Heart disease	1.4	1.9	5.0	1.8	-1.3	-1.0	-0.5	-1.6	2.2	-1.1	0.9	-0.0	-0.1	2.2
Irritable Bowel Disease (IBD)	1.3	3.1	17.9	-0.6	0.8	4.2	0.6	2.7	1.2	0.4	1.7	-1.0	-0.2	1.3
Major Depression (MDD)	1.3	1.6	5.6	0.7	1.6	-2.4	0.7	-0.6	-1.0	1.6	-0.6	1.3	1.4	-0.9
Hayfever/allergic rhinitis (self-reported)	1.3	1.8	5.6	-1.4	-1.6	-1.1	-1.1	-1.0	-0.2	-1.0	-1.0	-1.9	-2.4	-0.5
Falls in the last year	1.3	1.8	7.1	0.3	2.7	-1.2	1.5	1.7	-0.1	1.3	-1.9	0.6	0.8	0.2
Hypothyroidism/myxoedema (self-reported)	1.3	2.4	5.7	-2.4	-2.1	0.1	-1.5	0.4	-0.0	-1.3	-1.1	-2.4	-2.4	-0.3
Seen a psychiatrist for nerves, anxiety, tension or depression	1.3	1.7	5.4	0.5	1.1	-1.4	1.3	0.7	2.3	0.2	-1.5	-0.5	-0.4	2.3
Angina (self-reported)	1.3	1.8	4.3	-2.0	-1.0	0.9	-1.0	0.0	-1.2	-0.8	-1.4	-1.6	-2.1	-1.4
Breast cancer (self-reported)	1.3	1.5	3.7	1.5	1.9	0.9	0.2	-0.6	1.8	-0.2	1.2	0.2	1.0	1.9
Illnesses of father: High blood pressure	1.3	1.6	6.0	0.7	0.2	-0.5	0.3	-0.3	2.5	-0.6	-1.6	-1.3	-0.3	2.4
Risk taking	1.3	1.8	5.1	2.3	1.0	-1.8	1.6	0.5	-0.7	1.6	-0.6	1.8	1.2	-0.5
Alzheimer’s Disease (in mother)	1.2	1.4	6.5	-0.2	2.5	0.3	0.2	-0.4	1.6	-0.1	1.7	0.1	-0.2	1.7
Ulcerative Colitis (UC)	1.2	2.3	9.3	-1.7	1.1	3.1	-0.2	2.4	-0.4	0.1	0.3	-1.8	-1.4	-0.5
Crohns Disease (2012)	1.2	1.9	5.9	-0.5	1.9	2.4	1.7	2.2	0.4	1.7	0.6	-0.1	0.2	0.6
Eye problems/disorders: Diabetes related eye disease	1.2	1.3	3.8	-2.0	-1.3	0.7	-1.3	-0.4	-0.7	-1.5	-0.7	-0.5	-1.5	-0.9
Tinnitus: Yes, but not now, but have in the past	1.2	1.3	4.3	0.1	2.1	1.4	1.4	1.4	1.1	0.6	-0.2	-0.9	-0.6	1.2
Serious illness, injury or assault to yourself	1.2	1.5	7.1	-0.9	0.5	-0.7	-0.2	-0.4	0.3	-0.9	-2.7	-1.8	-1.9	0.0
Heel bone mineral density (BMD) T-score, automated (right)	1.2	2.7	14.6	-3.8	-1.2	1.1	-0.4	1.0	-1.5	-0.5	-1.5	-1.1	-1.5	-1.9
Shortness of breath walking on level ground	1.2	1.4	5.4	-1.9	0.0	-1.2	0.3	0.8	-0.3	-0.3	-2.3	-1.4	-1.5	-0.5
Eye problems/disorders: Cataract	1.2	1.4	7.7	1.0	-0.3	-2.8	-0.6	-2.3	-0.0	-0.5	0.5	0.8	-0.0	-0.1
Myopia	1.2	1.7	5.1	0.3	0.4	-0.9	-0.9	-1.9	2.2	-1.3	0.2	-0.7	-1.1	2.1
Average weekly fortified wine intake	1.1	1.2	5.5	1.7	0.8	1.1	-1.1	-0.2	-0.9	-0.5	2.3	0.0	0.8	-0.9
Bilateral oophorectomy (both ovaries removed)	1.1	1.2	4.5	-0.4	-0.2	0.9	-2.1	-0.7	-0.1	-1.8	0.7	-1.0	-1.6	-0.4
Heel bone mineral density (BMD) T-score, automated (left)	1.1	2.5	12.3	-3.5	0.2	1.4	0.4	1.6	-1.8	0.4	-1.3	-0.9	-0.7	-2.0
Nervous feelings	1.1	2.1	8.0	-1.0	-0.3	0.2	-1.9	-1.1	1.2	-2.8	-1.0	-2.0	-1.4	0.8
Pain all over the body in last month	1.1	1.1	4.8	-0.8	0.7	0.3	2.2	1.9	0.5	1.1	-0.8	-0.4	-0.3	0.7
Father’s age at death	1.1	1.5	3.9	-0.0	-1.4	-2.0	-1.1	-1.5	0.6	-0.8	-1.9	-1.2	-1.0	0.4
Frequency of tiredness / lethargy in last 2 weeks	1.1	1.8	7.6	-1.4	0.8	0.2	-0.3	0.4	0.2	-1.4	-2.8	-1.5	-2.2	-0.1
Forced expiratory volume in 1-second (FEV1), Best measure	1.1	3.4	11.7	0.7	1.6	-0.7	2.2	1.3	-2.1	3.4	0.6	1.6	2.3	-1.6
Leg pain on walking	1.1	1.4	3.7	-1.9	1.0	1.2	0.5	1.5	-0.9	0.3	-0.9	-1.5	-1.0	-1.1
Back pain experienced in last month	1.1	1.6	6.5	2.5	0.5	-1.0	0.0	0.0	0.6	0.9	1.7	1.8	1.6	0.8
Medication: Blood pressure	1.1	2.1	5.2	-1.1	-1.9	0.0	-2.3	-1.1	-0.8	-2.1	-1.5	-1.2	-1.4	-1.2
HbA1C	1.0	1.1	4.2	0.3	-0.8	-2.0	-1.1	-1.2	-1.1	-1.0	0.3	-0.4	-0.3	-1.2
Waist Hip Ratio (WHR)	1.0	4.6	10.0	3.2	2.0	0.0	2.8	1.2	0.3	2.7	2.2	2.0	3.2	0.9
Average weekly spirits intake	1.0	1.3	4.8	1.5	0.6	-0.5	2.2	0.3	0.6	1.6	0.9	0.3	1.2	0.9
Vitamin and mineral supplements	1.0	1.4	4.0	-1.9	-1.3	0.0	-0.5	-1.0	0.6	-0.9	-1.1	-1.4	-2.0	0.3
Medication: Levothyroxine sodium	1.0	1.8	4.2	-1.4	-2.1	-0.9	-1.8	-0.8	-0.2	-1.6	-0.9	-1.4	-1.6	-0.5
Frequency of tenseness / restlessness in last 2 weeks	1.0	1.5	5.6	-2.1	1.1	0.7	0.2	0.5	-0.2	-1.1	-2.4	-1.2	-1.3	-0.4
Standing height	1.0	10.1	59.6	-0.2	7.7	2.7	3.0	2.1	-1.0	3.4	3.5	1.7	1.9	-0.4
Number of children fathered	1.0	1.2	6.5	0.8	0.6	2.6	0.4	0.3	1.2	-0.0	1.3	0.1	0.5	1.2
Medication: Allopurinol	1.0	1.3	4.0	-0.0	1.0	1.3	0.5	1.0	2.0	-0.2	-0.8	-0.8	-1.0	2.0
Chest pain or discomfort	1.0	1.5	3.6	-0.1	0.9	-1.9	0.9	0.4	1.6	0.2	-1.7	-1.1	-1.2	1.6
Average weekly red wine intake	1.0	1.5	3.8	0.3	-0.3	-1.5	-0.2	-1.9	-1.2	0.7	1.9	1.4	1.3	-1.1
Fractured/broken bones in last 5 years	1.0	1.3	4.2	0.6	-1.7	-1.3	-0.7	-0.7	-0.8	-0.8	-2.0	-0.6	-1.5	-1.0
Supplements: Calcium	1.0	1.1	4.9	2.2	-0.4	-1.1	0.7	0.5	0.7	1.0	0.5	1.1	1.0	1.1
Reaction Time	0.9	1.6	4.4	-1.6	-1.9	0.5	-1.6	-0.3	0.6	-2.1	-1.2	-1.0	-1.3	0.3
Number of incorrect matches in round	0.9	1.5	4.7	1.0	-1.5	-2.2	-1.0	-1.6	1.2	-1.4	-0.1	-0.1	0.2	1.2
Lung cancer (father)	0.9	1.1	3.0	-1.7	0.4	1.7	0.8	1.3	-1.1	0.9	-0.5	0.3	-0.6	-0.9
Length of working week for main job	0.9	1.0	2.0	-1.3	-0.4	-0.4	-0.7	1.0	-1.1	-0.2	-1.4	-1.1	-1.1	-1.3
Tense / ‘highly strung’	0.9	1.5	6.5	-0.4	-0.2	-1.9	-0.4	-1.3	0.5	-1.4	-2.6	-1.0	-1.2	0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.9	1.4	5.2	-1.2	1.0	-1.3	-0.1	-0.5	1.4	-1.0	-2.3	-0.4	-1.0	1.2
Migraine (self-reported)	0.9	1.1	3.6	-0.3	1.8	1.9	-1.2	-0.4	-0.5	-0.9	1.4	-0.4	-0.4	-0.6
Mean time to correctly identify matches	0.9	1.7	4.3	-1.6	-1.2	-0.3	-1.6	-0.7	0.2	-2.1	-1.9	-1.1	-1.5	-0.1
Comparative height size at age 10	0.9	5.1	24.6	1.9	5.0	1.1	2.2	0.3	1.0	1.9	3.5	1.1	1.5	1.4
Qualifications: NVQ or HND or HNC or equivalent	0.9	1.0	3.8	-0.5	-0.7	1.3	0.9	0.6	1.8	-0.5	-0.1	-0.3	-0.5	2.0
Supplements: Vitamin C	0.9	1.1	3.0	1.1	-1.6	0.1	-1.7	-1.1	0.4	-1.3	1.1	0.4	0.8	0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.9	1.1	3.3	1.2	0.9	0.2	1.3	0.3	1.6	0.6	0.1	0.2	1.1	1.8
Smoking status: Previous	0.9	1.4	3.0	1.1	1.1	1.7	1.1	1.4	-0.4	1.4	1.7	0.9	0.8	-0.2
Medication for cholesterol	0.9	1.4	4.0	0.1	1.6	-0.5	2.0	0.5	0.2	2.0	0.2	1.2	1.7	0.5
Osteoarthritis (self-reported)	0.9	1.2	5.2	-1.5	0.5	2.3	0.6	2.2	-0.3	0.7	0.1	-0.0	0.1	-0.3
Wears glasses or contact lenses	0.9	1.1	4.5	-0.8	-0.1	-0.0	-1.6	-2.1	0.4	-1.5	0.5	-1.2	-0.1	0.3
Ever taken oral contraceptive pill	0.9	1.0	3.6	-1.9	0.7	0.5	0.6	1.2	0.1	0.5	-1.4	-1.2	-0.9	0.2
Alcohol drinker status: Never	0.9	1.1	2.9	0.8	1.7	0.8	-1.5	-0.5	-0.8	-1.4	1.2	-0.1	-0.0	-1.0
Irritability	0.9	1.5	10.8	-0.3	-0.9	-0.8	1.7	0.7	0.2	0.8	-3.3	-0.3	-0.3	0.4
Age started oral contraceptive pill	0.9	1.1	2.5	-0.4	-1.0	-1.6	-1.2	-0.8	1.0	-1.3	-1.6	-0.7	-0.7	0.9
Ovarian Cancer	0.8	1.1	2.9	-0.1	-0.9	-0.9	1.2	0.8	1.7	0.6	-1.4	-0.5	-0.3	1.7
Coronary Artery Disease (CAD)	0.8	0.9	2.2	-1.3	-1.3	-0.1	0.4	1.2	-0.1	0.2	-1.5	-1.3	-1.1	-0.2
Ulcerative Colitis	0.8	1.2	4.5	-1.0	2.1	1.1	0.4	2.0	-0.1	0.9	0.4	-1.1	-0.1	-0.1
Hypothyroidism (self reported)	0.8	1.8	4.6	-2.0	-2.1	-0.6	-0.8	-0.4	0.7	-1.0	-1.1	-1.8	-2.1	0.5
Sensitivity / hurt feelings	0.8	1.4	6.5	1.7	0.3	-0.1	0.7	0.3	0.1	0.0	0.7	2.1	2.5	0.4
Forced expiratory volume in 1-second (FEV1)	0.8	2.8	8.5	0.4	1.5	-0.4	2.0	1.4	-2.3	2.9	0.7	1.6	1.7	-1.9
Ever highly irritable/argumentative for 2 days	0.8	0.9	2.0	1.3	-0.4	-1.4	0.6	-1.4	0.9	-0.2	-1.2	-0.7	-0.7	0.8
Loud music exposure frequency	0.8	0.9	2.5	0.9	-1.2	-1.6	0.7	0.1	0.4	1.0	0.7	1.5	0.4	0.6
Headache pain in last month	0.8	1.4	6.0	-1.8	2.5	1.5	-0.3	0.9	-0.9	0.1	-0.5	-0.6	-0.7	-1.0
Medication: Ventolin 100micrograms inhaler	0.8	1.0	2.5	-1.2	-0.9	-0.9	-0.3	0.7	0.5	-0.8	-1.3	-1.6	-1.5	0.4
Forced vital capacity (FVC), Best measure	0.8	2.9	10.0	1.1	1.4	-1.3	2.1	1.0	-1.6	3.2	0.8	1.5	2.2	-1.2
Wheeze or whistling in the chest in last year	0.8	1.5	3.7	-0.5	-1.9	-1.3	0.6	0.7	0.7	-0.6	-1.3	-1.8	-1.9	0.5
Medication for pain relief, constipation, heartburn	0.8	1.4	6.2	2.5	-0.5	-1.5	0.2	-1.1	-0.0	0.3	0.4	1.4	1.9	0.1
Commuting to job workplace: Public transport	0.8	0.9	2.0	-0.6	-1.4	-1.2	-0.5	-0.8	-0.5	-0.6	-0.9	-1.3	-1.3	-0.5
High cholesterol (Self-reported)	0.8	1.3	4.8	-1.0	-2.2	0.2	-0.7	-0.6	1.3	-1.3	-0.3	-0.9	-1.7	1.1
Medication: Bendroflumethiazide	0.8	1.2	2.3	1.1	1.0	1.5	0.9	1.2	0.9	0.9	1.1	0.8	1.5	1.2
Average weekly beer plus cider intake	0.8	1.2	3.0	-0.2	0.6	1.3	-0.1	1.6	-1.7	0.7	1.5	0.4	0.3	-1.6
Bipolar Disorder (2018)	0.7	1.0	3.0	-0.7	1.1	-1.3	1.3	0.2	-0.0	1.5	0.0	1.7	1.0	0.1
Schizophrenia vs Biploar Disorder	0.7	0.9	3.4	1.5	1.0	1.3	-0.6	0.8	-0.6	-0.0	1.8	0.2	0.5	-0.5
Worry (Nagel 2018)	0.7	1.5	4.4	-1.6	-0.1	-0.6	-1.5	-1.1	0.5	-2.1	-1.5	-1.5	-1.2	0.2
Mean Putamen Volume	0.7	0.7	2.8	-0.1	0.2	0.4	-0.3	0.3	-1.0	-0.2	1.3	1.7	1.3	-0.8
Neuroticism (2016)	0.7	1.0	4.6	0.6	-1.4	-2.1	-0.7	-0.6	0.7	-0.8	-1.1	-0.3	-0.4	0.7
Primary Biliary Cirrhosis	0.7	1.0	6.9	-0.8	2.6	0.2	-0.9	-0.1	-0.7	-0.5	0.8	-0.1	-0.2	-0.9
Lung FEV1/FVC ratio	0.7	3.4	14.5	-3.0	0.2	3.8	-1.0	1.2	-2.2	-0.3	0.4	-0.9	-0.6	-2.2
Lung FVC	0.7	3.4	17.4	1.0	-2.4	-4.2	0.2	-0.5	-2.1	1.1	-1.5	0.7	0.4	-2.0
Hand grip strength (left)	0.7	1.9	6.2	2.1	-0.6	-0.2	-0.1	-0.4	-1.2	0.8	2.5	1.8	1.9	-1.0
Ever had hysterectomy (womb removed)	0.7	0.8	2.3	1.5	-0.5	-1.4	-1.4	-1.1	0.1	-0.9	0.4	0.4	-0.5	0.0
Systolic blood pressure, automated reading	0.7	1.9	6.9	2.2	-0.5	0.0	0.9	-0.4	-0.1	1.1	2.6	1.6	2.0	0.1
Medication for hormone replacement therapy	0.7	0.8	2.0	-0.3	-1.3	0.8	-0.8	0.5	0.5	-1.3	-0.3	-1.3	-1.4	0.4
Supplements: Zinc	0.7	0.8	1.9	1.0	-1.2	-1.3	-1.4	-1.3	-0.0	-0.7	0.3	-0.6	-0.3	-0.2
Medication: Metformin	0.7	1.0	2.8	-1.0	1.1	0.3	0.5	0.7	-1.7	0.8	0.9	0.7	0.8	-1.5
Impedance of leg (right)	0.7	3.2	9.5	3.1	2.8	-1.1	1.8	0.2	1.5	1.7	1.2	1.0	1.5	1.9
Ever unenthusiastic/disinterested for a whole week	0.7	0.9	2.2	-0.9	-0.1	-0.8	-0.9	-1.4	-1.4	-0.5	0.1	0.9	-0.3	-1.5
Trunk fat-free mass	0.7	3.9	8.9	-2.6	2.5	2.6	1.9	3.0	-1.2	2.1	1.6	0.5	0.5	-0.9
Time employed in main current job	0.7	0.8	2.6	0.7	0.1	0.1	-0.8	-0.4	1.4	-0.6	0.2	-1.6	-0.6	1.3
Alcohol intake versus 10 years previously	0.7	1.0	3.8	-0.8	0.1	1.7	-1.5	-1.1	-0.2	-1.9	0.6	-0.2	-0.4	-0.4
Trunk predicted mass	0.7	3.8	9.0	-2.5	2.6	2.7	1.9	3.0	-1.1	2.1	1.5	0.4	0.5	-0.9
Neck or shoulder pain in last month	0.7	1.0	2.7	0.1	-1.6	-1.0	-1.6	-1.2	-0.1	-1.2	-0.1	-0.8	-0.6	-0.4
Alcohol intake frequency.	0.7	1.7	7.8	-0.4	2.8	0.9	1.6	1.3	-0.4	0.9	-0.3	1.7	1.4	-0.3
Had major operations	0.7	0.8	5.9	-0.2	-0.2	-0.8	-0.0	0.9	-0.6	0.6	-2.4	-0.1	0.4	-0.6
Family relationship satisfaction	0.7	0.9	2.8	-0.9	0.0	-0.7	-0.4	-0.1	-1.4	-0.2	-0.9	-0.8	-1.5	-1.7
Knee pain experienced in last month	0.7	1.1	2.0	0.3	1.3	-0.8	1.2	0.6	1.2	1.1	-0.5	1.4	0.9	1.4
Loneliness, isolation	0.7	0.9	2.9	-0.2	-0.8	-1.7	-0.8	-0.8	0.1	-1.3	-1.6	-0.7	-0.7	-0.1
Mother’s age at death	0.7	0.8	2.5	-0.3	1.6	0.4	-0.1	-0.5	-1.4	0.3	0.3	0.8	1.2	-1.4
Medication: Lisinopril	0.7	1.0	3.1	-0.5	-0.1	-1.1	-0.6	-0.7	-1.6	-0.6	-1.1	-0.3	-0.9	-1.8
Pain experienced in last month	0.7	1.1	2.8	0.1	-1.5	-0.8	-1.4	-1.7	0.3	-1.5	0.0	-0.9	-1.1	0.1
Alzheimer’s Disease (in father)	0.6	0.6	2.7	1.6	-0.1	-0.9	-0.2	-1.1	0.7	-0.7	0.5	0.3	0.0	0.8
Alzheimer’s Disease (including proxy)	0.6	0.9	2.2	0.1	1.4	-1.1	0.0	-1.4	1.5	-0.6	0.6	0.2	-0.6	1.4
Verbal and Numeric Reasoning (VNR)	0.6	1.4	3.8	-1.1	1.1	1.3	0.6	0.8	-1.9	1.1	1.1	0.6	0.8	-1.8
Height	0.6	11.8	70.2	-1.3	8.4	3.9	1.1	1.5	-3.4	2.3	3.1	1.2	0.8	-3.1
Systolic Blood Pressure	0.6	3.1	11.5	3.4	0.4	0.1	2.3	0.3	1.0	2.2	1.6	1.6	2.1	1.4
Medication: Co-codamol	0.6	0.7	1.3	-0.6	-0.9	-1.1	-1.1	-0.8	-0.0	-1.2	-0.2	-0.8	-1.1	-0.3
Townsend deprivation index at recruitment	0.6	0.9	4.0	-0.0	-1.0	-0.8	-0.1	-0.3	-0.0	-0.7	-2.0	-1.2	-1.4	-0.2
Relative age voice broke	0.6	0.8	2.3	1.2	1.5	0.8	0.7	-0.3	-0.9	0.9	0.9	0.5	0.9	-0.8
Age when periods started (menarche)	0.6	1.4	4.0	-1.1	0.5	-2.0	0.2	0.5	-1.6	0.2	-1.8	0.1	-0.7	-1.7
Sitting height	0.6	4.4	20.1	-1.2	4.5	2.4	2.4	1.9	-1.1	2.5	2.0	0.3	0.3	-0.7
Impedance of leg (left)	0.6	2.8	9.0	2.8	3.0	-1.0	1.4	-0.3	1.1	1.5	1.4	0.9	1.5	1.5
Forced vital capacity (FVC)	0.6	2.3	7.4	1.1	1.5	-1.1	2.0	1.0	-1.6	2.7	0.7	1.3	1.5	-1.3
Qualifications: None of the above	0.6	1.3	3.5	-0.5	-0.1	1.9	-0.7	0.4	1.9	-1.4	-0.1	-0.5	-0.9	1.7
Medication: Ramipril	0.6	0.8	5.6	-0.1	-0.2	2.4	-0.1	-0.2	0.3	-0.5	1.4	0.6	0.2	0.3
Pulse rate	0.6	1.0	2.6	0.7	-0.7	-0.7	-0.2	-1.1	1.6	-0.9	0.1	-1.1	-1.3	1.5
Pulse wave Arterial Stiffness index	0.6	0.7	1.8	1.3	0.4	-0.5	0.0	-0.8	1.4	-0.4	0.8	-0.4	0.0	1.3
Exposure to tobacco smoke at home	0.6	0.7	2.3	1.3	0.9	-0.9	0.0	-1.5	0.1	0.1	0.6	0.4	1.3	0.2
Hair/balding pattern: Pattern 4	0.6	1.4	10.7	-0.6	-3.3	-1.4	-0.2	0.4	-0.1	0.0	-1.1	-0.5	-0.3	-0.1
Birth weight of first child	0.6	1.1	3.0	-0.8	0.9	1.2	-0.5	1.1	-1.7	0.0	1.2	0.3	-0.7	-1.7
Qualifications: O levels/GCSEs or equivalent	0.6	1.0	4.5	0.6	-0.2	-0.8	-0.6	-0.4	-2.1	0.3	0.6	-0.0	-0.1	-2.1
Chronic bronchitis/emphysema (mother)	0.6	0.7	2.2	-0.3	1.3	1.5	1.1	0.3	-0.7	0.8	0.5	0.3	0.4	-0.7
Pulse wave peak to peak time	0.6	0.7	2.0	-1.4	0.3	0.7	0.2	1.1	-1.3	0.6	-0.7	0.5	-0.0	-1.2
Qualifications: College or University degree	0.6	1.9	7.9	0.4	-1.1	-2.8	0.2	-0.6	-1.2	0.9	-2.8	-0.8	0.3	-1.1
Heart disease (mother)	0.6	0.7	5.6	0.1	-0.2	1.1	-0.1	0.7	-0.0	0.3	2.4	0.4	0.6	0.0
Arm predicted mass (right)	0.6	3.1	6.9	-1.8	2.2	2.1	2.2	2.6	-1.0	2.2	1.6	0.7	0.7	-0.7
Whole body fat-free mass	0.6	3.5	8.0	-2.7	2.4	2.8	1.7	2.7	-1.1	1.7	1.4	0.4	0.2	-0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.7	5.3	0.2	-0.0	-2.3	-0.3	-1.0	-0.5	-0.0	-0.4	0.6	0.2	-0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.6	1.3	3.8	-0.9	-1.6	-1.2	0.2	0.1	-1.9	1.1	-0.1	0.7	0.7	-1.9
Whole body water mass	0.6	3.3	8.0	-2.8	2.2	2.8	1.6	2.6	-1.0	1.7	1.4	0.3	0.1	-0.8
Average weekly champagne plus white wine intake	0.6	0.9	2.6	-1.1	-0.2	-1.5	-0.6	-0.0	0.2	-0.5	-1.6	-1.1	-1.3	0.2
Hearing aid user	0.6	0.7	4.4	-1.2	0.9	2.1	-0.1	0.5	-0.5	-0.2	0.5	0.5	-0.0	-0.6
Eye problems/disorders: Glaucoma	0.6	0.7	2.8	-0.8	1.7	0.1	0.0	0.2	-1.0	-0.3	-1.0	-0.5	-0.5	-1.2
Ever smoked	0.6	1.0	6.1	2.5	-0.4	-0.6	0.7	0.2	0.0	0.9	1.5	0.2	1.0	0.2
Basal metabolic rate	0.6	3.4	8.6	-2.8	2.4	2.9	1.6	2.5	-0.8	1.6	1.6	0.4	0.1	-0.7
Arm fat-free mass (left)	0.6	2.9	7.2	-2.2	2.0	2.7	1.7	2.4	-0.5	1.6	1.9	0.3	0.2	-0.3
Cholesterol lowering medication	0.6	0.9	3.4	0.3	-1.1	-0.1	-1.8	-0.7	0.3	-1.8	-0.0	-0.4	-1.2	0.0
Pack years of smoking	0.6	0.9	3.4	0.0	0.2	1.9	0.1	1.2	1.4	-0.2	0.6	0.5	0.4	1.4
LDL Cholesterol	0.5	0.7	1.6	-0.7	-1.3	0.3	-1.3	-0.2	-0.1	-1.2	-0.3	-1.1	-1.3	-0.1
Lupus	0.5	0.8	2.4	1.6	-0.5	-1.1	0.1	-1.1	1.0	-0.5	0.8	0.4	0.7	1.0
Rheumatoid Arthritis	0.5	0.7	3.7	-0.1	0.3	1.9	0.4	0.5	1.3	-0.3	0.3	0.0	0.3	1.4
Triglycerides	0.5	0.8	1.5	0.2	-0.4	0.8	-1.2	-1.0	-0.5	-1.0	1.0	-1.2	-1.2	-0.7
Type 2 Diabetes (T2D) (2012)	0.5	0.5	3.7	-0.4	-1.9	0.2	-0.1	-0.0	-0.0	-0.4	-0.8	0.2	-1.0	-0.5
Number of treatments/medications taken	0.5	0.9	4.0	-0.3	-0.3	0.6	-0.9	-0.4	0.7	-1.5	0.0	-1.4	-2.0	0.4
Diabetes (father)	0.5	0.7	2.7	-1.6	-0.4	-0.2	0.4	1.0	0.3	0.4	-1.3	-0.9	-0.8	0.2
Severe depression (siblings)	0.5	0.5	2.6	-0.5	-0.6	-0.3	1.6	0.2	0.1	0.8	-1.2	0.0	-0.6	0.1
Leg fat-free mass (left)	0.5	2.4	7.6	-2.7	1.9	2.8	1.2	2.0	-0.5	0.9	1.0	0.1	-0.4	-0.4
Medication: Atenolol	0.5	0.6	3.9	-2.0	0.9	0.2	-0.5	0.5	0.0	-0.4	-0.3	-0.5	-0.8	-0.1
Leg predicted mass (left)	0.5	2.5	7.9	-2.7	2.0	2.8	1.3	2.0	-0.5	1.0	1.1	0.1	-0.3	-0.4
Had other major operations	0.5	0.6	1.3	0.3	0.1	0.8	-0.8	0.8	1.1	-0.7	0.4	-0.9	-0.5	1.1
Medication: Simvastatin	0.5	0.8	3.9	-0.9	-2.0	-0.6	-0.9	-0.6	-0.8	-0.5	-0.2	0.5	-0.2	-0.9
Weight	0.5	2.3	6.7	-2.6	2.1	2.6	1.1	1.5	-0.3	0.8	1.8	0.2	-0.2	-0.2
Qualifications: A levels/AS levels or equivalent	0.5	1.2	3.4	-0.4	-0.5	-0.4	1.1	0.6	-1.8	1.5	-1.6	0.1	0.2	-1.6
Breastfed as a baby	0.5	0.7	2.2	0.8	-1.2	-1.5	-0.4	-0.8	0.5	-0.7	-0.7	-0.8	-0.3	0.4
Blood clot in the leg (DVT)	0.5	0.7	1.9	1.2	-0.6	-1.1	-0.2	-0.1	-1.0	0.3	0.5	0.5	1.4	-0.9
Arm fat-free mass (right)	0.5	2.7	5.8	-2.0	2.0	2.4	1.7	2.3	-0.9	1.8	1.7	0.6	0.4	-0.6
Number of full brothers	0.5	0.7	3.8	1.9	-0.9	-0.6	0.1	-0.9	0.8	-0.2	0.5	0.4	0.2	0.7
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.5	1.3	1.1	0.5	-0.4	-0.6	0.5	-1.1	-0.2	0.8	0.9	0.6	-0.9
Health satisfaction	0.5	0.6	1.8	-1.0	1.1	0.0	-0.3	-0.2	0.4	-0.7	-1.0	-1.1	-1.3	0.2
Emphysema/chronic bronchitis	0.5	0.5	1.1	-0.7	0.8	-1.0	0.9	0.1	0.6	0.5	-0.7	-0.2	-1.1	0.6
Medication: Omeprazole	0.5	0.6	1.8	-0.4	-0.6	-1.2	-0.5	-0.3	-0.2	-0.6	-1.4	-1.2	-0.8	-0.2
Number of full sisters	0.5	0.7	1.8	-1.0	-0.8	0.4	0.2	0.0	1.3	-0.9	-0.6	-0.6	-0.7	1.2
Age at last live birth	0.5	0.7	2.6	0.9	0.8	0.1	0.2	0.2	-1.2	0.7	0.0	0.7	1.6	-1.1
Illnesses of siblings: Diabetes	0.5	0.7	3.0	-1.7	0.3	0.5	0.6	0.4	-1.3	0.1	-0.0	0.1	-0.5	-1.3
Leg fat-free mass (right)	0.5	2.6	7.5	-2.7	2.1	2.7	1.1	1.8	-1.0	1.1	1.1	0.2	-0.2	-0.9
Handedness (chirality/laterality): Left-handed	0.5	0.6	3.8	2.0	0.4	-0.6	0.9	-0.4	0.3	0.3	-0.3	0.6	0.8	0.4
Friendships satisfaction	0.5	0.6	4.0	0.6	0.1	1.3	0.5	-0.3	-0.6	0.1	2.0	0.2	0.2	-0.5
Smoking status: Current	0.5	0.7	3.6	-0.3	-1.9	-0.7	-0.5	-0.3	0.2	-0.9	-0.6	-1.3	-0.7	0.1
Leg predicted mass (right)	0.5	2.5	7.6	-2.8	2.1	2.7	1.1	1.8	-0.8	1.0	1.1	0.1	-0.2	-0.7
Medication: Paracetamol	0.5	0.7	4.9	-0.7	-0.4	2.2	0.4	0.9	-0.3	0.4	1.0	0.2	0.2	-0.3
Medication: Atorvastatin	0.5	0.6	1.5	-0.2	-0.9	0.9	-0.4	-0.8	0.5	-1.2	-0.3	-1.2	-1.1	0.4
Ever depressed for a whole week	0.5	0.6	2.0	0.1	0.6	-0.4	-0.2	-0.5	-1.4	0.4	0.3	1.1	0.3	-1.3
Basal cell carcinoma (self-reported)	0.5	0.6	1.4	-0.9	-0.8	0.4	-0.3	-0.1	-0.8	-0.5	-0.6	-1.1	-1.2	-0.9
Heart disease (siblings)	0.5	0.6	2.1	-1.5	-0.1	1.3	0.5	1.3	0.1	0.1	0.5	-0.3	-0.7	0.1
Impedance of whole body	0.5	2.4	9.6	2.6	3.1	-1.6	0.6	-1.5	1.1	0.5	0.4	0.6	0.7	1.3
Arm predicted mass (left)	0.5	2.7	6.9	-2.4	1.7	2.6	1.6	2.4	-0.6	1.6	1.8	0.2	0.1	-0.4
Schizophrenia (2014)	0.4	0.9	3.2	0.5	1.5	0.2	0.7	1.0	-0.2	1.2	0.8	0.9	1.8	0.0
BMI	0.4	2.2	17.1	-4.1	-1.0	1.6	0.2	1.5	-0.0	-0.2	-0.3	-0.7	-0.9	-0.2
Allergy or Eczema	0.4	1.1	2.8	0.3	-0.4	-1.6	-1.1	-1.7	0.7	-0.8	-0.8	-1.3	-1.5	0.5
Type 2 Diabetes (T2D) (2018)	0.4	0.8	3.2	-0.4	-0.6	-0.7	0.6	-0.1	-1.8	0.6	-0.5	0.9	0.1	-1.8
Hearing difficulty/problems: Yes	0.4	0.7	2.8	-0.5	-0.4	0.2	-0.3	0.8	-1.6	-0.2	-0.5	0.2	0.5	-1.7
Relative age of first facial hair	0.4	0.8	3.0	1.7	1.2	1.1	0.3	-0.8	-0.3	0.3	1.1	0.8	0.4	-0.3
Other serious medical condition/disability diagnosed by doctor	0.4	0.5	1.7	-0.5	0.4	-0.9	0.5	0.9	-0.6	0.4	-1.3	-0.2	-0.5	-0.7
Diabetes (mother)	0.4	0.5	1.9	-1.1	-0.3	1.4	0.6	-0.2	-0.6	0.1	-0.5	-0.6	-0.6	-0.7
Hand grip strength (right)	0.4	1.2	4.0	0.4	0.1	0.0	0.4	0.4	-1.6	1.2	2.0	1.2	1.3	-1.4
Qualifications: CSEs or equivalent	0.4	0.6	1.9	0.3	1.4	1.2	0.8	1.4	0.3	0.4	0.0	-0.1	0.2	0.3
Diverticular disease/diverticulitis (self-reported)	0.4	0.5	1.9	-0.1	0.2	0.9	0.5	0.0	1.3	0.2	0.2	0.0	0.3	1.4
Chronic bronchitis/emphysema (father)	0.4	0.5	2.0	-0.7	-0.0	0.7	0.2	1.4	-0.3	0.0	-0.4	-1.4	-0.1	-0.2
Trunk fat mass	0.4	1.6	5.4	-2.2	2.3	1.7	1.0	0.7	0.5	0.5	1.4	0.2	-0.5	0.5
Waist circumference	0.4	1.3	4.7	-1.9	0.6	2.2	1.1	1.5	0.1	0.5	1.4	0.3	0.1	0.1
Diabetes (self-reported)	0.4	0.6	1.8	-0.3	0.3	1.0	-0.0	0.1	-1.3	0.2	0.8	1.0	0.7	-1.3
Arm fat percentage (right)	0.4	1.4	7.1	-2.7	-0.2	0.9	-0.7	-0.1	1.1	-1.3	-0.1	-0.9	-1.7	0.8
Happiness	0.4	0.5	1.6	-0.0	-0.2	0.8	-0.5	-0.8	0.7	-1.3	0.2	-0.9	-0.9	0.4
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.5	1.9	-0.4	0.2	-0.6	0.8	0.2	0.8	0.0	-1.4	-0.4	-0.9	0.7
Illnesses of mother	0.4	0.5	2.1	0.3	-0.3	-0.7	0.5	1.4	-0.2	0.7	-1.2	-0.6	-0.3	-0.1
Pulse wave reflection index	0.4	0.5	1.6	1.3	0.1	-1.1	0.6	-0.2	-0.2	0.4	0.5	0.9	1.2	-0.1
Medication: Paracetamol	0.4	0.7	4.6	-0.6	-0.2	2.1	0.5	0.9	0.6	-0.1	0.3	-0.9	-0.5	0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	1.7	-0.8	1.1	0.6	0.8	-0.1	-0.0	0.8	1.3	0.2	0.4	0.1
Leg fat mass (right)	0.4	1.5	6.7	-2.6	0.8	2.1	0.7	1.4	0.7	0.1	1.0	-0.4	-0.8	0.7
Suffer from ‘nerves’	0.4	0.7	2.4	0.3	0.1	-0.3	-0.6	-0.6	1.2	-1.6	-0.7	-0.7	-0.6	1.1
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	1.9	0.7	-0.5	-0.2	-0.7	-0.7	-0.9	0.5	1.4	0.2	0.8	-0.7
Ever had bowel cancer screening	0.4	0.5	1.7	-0.7	0.0	0.8	-1.0	-0.5	-0.1	-1.3	0.3	-0.7	-0.5	-0.1
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.4	0.9	-0.2	-0.9	-1.0	0.6	0.3	0.3	0.4	-1.0	-0.7	-0.9	0.3
Qualifications: nursing, teaching	0.4	0.6	1.8	0.6	0.6	-0.5	0.6	0.2	-1.0	0.9	0.6	0.1	1.4	-0.8
Mouth/teeth dental problems: Mouth ulcers	0.4	0.7	2.1	0.4	0.8	-0.6	-0.5	0.4	1.1	-1.0	-0.8	-1.5	-0.3	1.0
Arm fat mass (left)	0.4	1.4	8.6	-2.9	0.9	1.8	0.5	1.3	0.4	0.1	0.5	-0.4	-1.0	0.3
Tinnitus: Yes, now most or all of the time	0.4	0.5	1.6	-0.2	0.4	1.3	0.0	0.2	1.1	-0.2	0.1	-0.6	-0.9	1.0
Diastolic blood pressure, automated reading	0.4	1.3	5.0	2.2	-0.1	-0.3	0.8	-0.8	0.0	0.7	2.2	1.1	1.3	0.1
Unable to work because of sickness or disability	0.4	0.5	1.3	0.2	0.0	0.5	0.9	1.1	-0.6	0.8	0.8	0.8	0.8	-0.5
Leg fat mass (left)	0.4	1.5	7.6	-2.8	1.0	2.0	0.5	1.2	0.5	0.1	1.1	-0.4	-0.8	0.4
Bipolar Disorder or Schizophrenia	0.3	0.8	2.7	0.1	1.3	-0.8	0.5	0.7	-0.0	1.2	0.5	1.3	1.7	0.1
Neuroticism (Nagel 2018)	0.3	0.7	2.8	-0.7	-0.9	-0.4	-0.7	-0.7	0.0	-1.7	-1.7	-0.6	-0.0	-0.0
Age at First Birth	0.3	0.4	1.8	0.4	-0.9	-0.3	-0.0	-1.0	0.4	-0.2	0.1	1.3	0.7	0.4
Bipolar Disorder (2011)	0.3	0.3	1.2	-0.5	0.4	0.6	0.0	0.0	0.4	0.5	-1.1	0.9	0.2	0.4
Body Mass Index (BMI) (2010)	0.3	0.4	2.2	0.0	-0.0	0.4	-1.1	-0.2	-0.2	-0.2	1.5	0.5	0.5	-0.3
Fasting Glucose	0.3	0.3	1.5	0.5	1.2	-0.2	0.7	0.9	0.0	-0.1	-0.1	-0.5	-0.1	-0.6
HDL Cholesterol	0.3	0.5	1.3	-1.1	0.6	0.4	0.0	0.8	0.9	-0.4	-0.5	-0.4	-1.0	0.9
Blood White Count	0.3	2.4	7.1	-2.1	1.3	1.5	2.2	2.7	0.8	1.5	0.2	0.7	0.9	1.2
Chronotype (morning person)	0.3	0.7	2.2	0.7	-0.0	0.3	-0.8	-0.6	-0.2	-0.2	1.2	1.5	1.4	0.0
Frequency of depressed mood in last 2 weeks	0.3	0.4	1.0	-0.7	1.0	0.5	1.0	0.4	-0.8	0.3	-0.0	-0.2	-0.0	-0.8
Pack years adult smoking proportion	0.3	0.5	1.4	0.3	-0.0	1.2	0.0	0.8	1.1	-0.2	0.4	0.5	0.5	1.1
Fed-up feelings	0.3	0.5	1.3	-1.2	-0.4	-0.2	-0.4	0.3	-0.8	-1.0	-0.8	-0.0	-0.2	-0.9
Stomach or abdominal pain in last month	0.3	0.4	1.0	-0.9	0.0	0.1	0.3	0.1	1.0	-0.1	1.0	0.4	-0.9	1.0
Body mass index (BMI)	0.3	1.2	7.0	-2.7	-1.3	1.6	-0.2	0.8	0.1	-0.6	0.3	-0.5	-1.1	-0.1
Alcohol usually taken with meals	0.3	0.4	2.3	-1.5	-0.0	-1.1	-0.1	-0.3	-0.6	-0.1	-0.6	0.0	0.3	-0.6
Hair/balding pattern: Pattern 2	0.3	0.4	1.5	-0.1	-0.5	1.2	-0.0	0.5	-0.1	0.0	-0.9	0.9	0.7	-0.2
Financial difficulties in last 2 years	0.3	0.4	1.4	0.5	0.2	-1.1	-0.4	0.3	-0.1	-0.7	-1.2	0.5	0.2	-0.2
Heart attack	0.3	0.4	1.4	0.0	-0.4	-1.2	-0.6	-1.0	-0.2	-1.0	-0.5	-0.1	-0.6	-0.3
Impedance of arm (right)	0.3	1.4	4.6	1.5	2.1	-1.0	-0.3	-1.7	1.3	-0.7	-0.1	-0.2	-0.3	1.3
Hip circumference	0.3	1.4	7.6	-2.8	0.6	2.0	-0.4	-0.0	0.1	-0.5	1.1	-0.3	-1.4	-0.1
Worrier / anxious feelings	0.3	0.5	2.2	-0.9	0.4	0.2	-1.1	-0.4	0.6	-1.5	-0.7	-0.2	0.5	0.6
Hair/balding pattern: Pattern 3	0.3	0.5	1.4	-1.2	1.0	0.4	0.7	0.8	0.3	0.6	-0.4	-0.8	-0.6	0.3
Number of live births	0.3	0.4	1.2	-0.1	-0.7	-0.1	0.3	0.1	1.1	0.3	0.6	0.1	-0.8	1.1
Mouth/teeth dental problems: Dentures	0.3	0.5	1.7	0.5	1.2	1.3	-0.1	0.6	-0.3	-0.0	0.9	0.6	1.0	-0.2
Asthma	0.3	0.5	1.7	-0.6	0.2	-1.3	0.3	-0.1	0.3	-0.5	-1.1	-0.7	-1.3	0.3
Medication: Cholesterol lowering	0.3	0.5	1.3	-1.1	0.2	1.0	0.2	-0.0	-0.8	0.3	1.0	0.7	-0.0	-0.6
Impedance of arm (left)	0.3	1.6	8.3	1.5	2.9	-1.2	-0.2	-1.7	1.0	-0.6	-0.5	-0.0	-0.2	1.0
Arm fat mass (right)	0.3	1.4	8.4	-2.9	0.6	1.9	0.2	1.0	0.5	-0.3	0.5	-0.6	-1.1	0.4
Peak expiratory flow (PEF)	0.3	0.7	2.5	-1.1	0.3	-0.3	0.3	-0.1	-1.6	1.0	0.5	0.3	-0.4	-1.5
Medication for cholesterol, blood pressure or diabetes	0.3	0.6	4.1	2.0	-0.8	-0.6	-0.4	0.3	0.1	-0.1	-0.5	-0.7	0.3	-0.0
Glaucoma (self-reported)	0.3	0.4	2.2	-0.7	1.5	-0.3	0.6	-0.5	0.1	0.0	-0.7	-0.3	-0.4	0.0
Medication: Amlodipine	0.3	0.4	1.9	-0.9	-0.2	-0.1	-0.3	1.4	0.0	-0.3	-1.1	-0.5	-0.7	-0.0
Birth weight	0.3	0.7	2.2	-0.6	1.3	1.4	0.1	0.0	0.3	0.1	0.5	-1.3	-1.5	0.2
Age at first live birth	0.3	0.5	3.0	-0.7	0.7	1.7	0.0	0.7	0.3	-0.0	-0.6	-0.6	0.3	0.3
Eye problems/disorders: None of the above	0.3	0.3	2.0	0.2	-0.3	1.4	-0.0	0.6	-0.3	0.4	0.8	-0.5	0.3	-0.2
Mouth/teeth dental problems: Loose teeth	0.3	0.3	0.9	-0.9	0.1	-0.7	0.1	0.8	-0.4	0.1	-0.8	0.9	0.2	-0.4
Whole body fat mass	0.3	1.4	6.5	-2.5	1.9	1.6	0.8	0.9	0.4	0.4	1.0	-0.1	-0.7	0.4
Overall health rating	0.3	0.6	2.1	-1.0	0.4	0.6	-0.1	0.1	-0.1	-1.4	-1.1	-0.7	-0.9	-0.3
Arm fat percentage (left)	0.3	1.2	6.9	-2.6	0.0	0.8	-0.5	0.0	0.8	-1.1	-0.3	-0.8	-1.6	0.5
Mood swings	0.3	0.5	2.6	-0.4	0.0	-0.5	0.5	0.1	0.8	-0.5	-1.6	-0.9	-0.6	0.8
Asthma (self-reported)	0.3	0.7	2.2	-0.8	0.1	-1.1	0.3	0.2	0.4	-0.5	-1.4	-1.1	-1.5	0.3
Miserableness	0.3	0.6	3.7	0.2	-0.2	-0.5	1.9	0.5	0.5	1.0	-0.4	0.3	0.6	0.7
Guilty feelings	0.3	0.4	1.6	1.0	-0.3	-0.5	0.3	0.4	0.4	-0.3	-1.3	0.0	0.9	0.6
Financial situation satisfaction	0.3	0.4	1.4	-0.4	-0.4	-0.3	-0.2	-1.2	-0.9	-0.7	0.1	0.6	0.0	-1.1
Number of operations (self-reported)	0.3	0.5	1.4	1.0	0.7	-0.4	-0.2	-0.4	1.2	-0.4	-0.8	-0.2	0.2	1.2
Medication: Omeprazole (e.g. Zanprol)	0.3	0.3	1.5	-0.2	1.2	-1.0	-0.0	-0.6	0.0	-0.1	-0.4	-0.5	-0.3	0.0
Heart attack/myocardial infarction (self-reported)	0.3	0.4	2.0	0.4	-0.5	-1.4	-0.5	-1.0	0.0	-0.9	-0.4	0.0	-0.4	-0.1
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	1.7	0.9	-0.6	-0.8	-0.1	0.1	-0.7	0.4	0.4	0.2	1.3	-0.6
Depressed Affect (Nagel 2018)	0.2	0.4	1.4	-1.2	-0.4	-0.1	-0.3	-0.0	-0.7	-0.7	-0.8	-0.8	-0.2	-0.8
Intelligence (Savage-Jansen 2018)	0.2	0.5	1.2	-0.3	-0.2	-0.1	1.0	0.6	-1.0	1.1	0.8	0.6	0.1	-1.0
Schizophrenia (2018)	0.2	0.3	1.7	0.7	0.7	-0.0	-0.4	0.7	0.0	0.3	0.5	0.2	1.3	0.1
Breast Cancer	0.2	0.4	1.9	-0.6	-1.4	-0.2	-0.7	-0.6	-0.3	-0.8	-0.4	0.2	0.3	-0.4
Blood Platelet Count	0.2	2.1	4.9	-1.8	-1.7	2.0	-1.4	-0.5	1.0	-2.0	0.6	-0.3	-2.2	0.7
Heel T-Score	0.2	2.0	12.5	-3.5	-0.0	0.7	0.5	1.4	-1.5	0.6	0.4	0.2	1.3	-1.5
Smoking Status	0.2	0.5	1.8	0.8	-0.8	0.7	0.7	1.0	-0.3	0.8	1.3	-0.2	0.4	-0.1
Cardiovascular Disease	0.2	0.7	3.7	0.3	-0.5	-0.9	0.4	-1.1	-0.0	0.2	0.0	1.9	1.2	0.0
Respiratory disease	0.2	0.5	3.6	0.8	0.2	-1.9	0.4	-1.0	-0.2	-0.0	-0.3	0.4	-0.4	-0.2
Neuroticism	0.2	0.4	1.0	0.4	-0.2	-1.0	0.8	-0.4	-0.0	-0.0	-0.5	0.9	1.0	0.1
Tanning	0.2	1.9	5.3	2.2	0.4	1.3	0.4	-0.1	1.0	0.7	2.3	1.4	2.0	1.2
Trunk fat percentage	0.2	0.9	3.1	-1.5	1.8	0.8	0.5	-0.3	1.0	-0.1	0.9	-0.1	-0.7	0.9
Current tobacco smoking	0.2	0.4	2.4	-0.2	-1.5	0.2	0.2	0.3	0.7	-0.4	-0.0	-0.8	-0.2	0.7
Maternal smoking around birth	0.2	0.3	1.3	-0.3	-0.0	1.1	0.7	0.6	0.4	-0.2	0.1	0.7	0.3	0.4
Hayfever, allergic rhinitis or eczema	0.2	0.4	0.9	0.8	-0.2	-1.0	-0.8	-0.8	0.4	-0.3	-0.4	-0.7	-0.8	0.2
Past tobacco smoking	0.2	0.4	1.8	-1.4	0.2	-0.3	-0.3	-0.7	0.4	-0.6	-1.1	0.1	-0.1	0.3
Mouth/teeth dental problems	0.2	0.4	1.9	0.2	-0.9	-0.5	-0.4	-1.4	-0.1	-0.1	0.9	0.1	-0.3	-0.1
Neuroticism score	0.2	0.3	1.5	-0.1	0.2	-1.0	0.5	-0.2	0.4	-0.7	-1.2	-0.2	0.1	0.4
Noisy workplace	0.2	0.2	0.6	0.5	0.8	-0.5	0.1	-0.5	-0.4	-0.3	0.3	0.6	-0.3	-0.5
Gout (self-reported)	0.2	0.2	0.8	0.3	0.7	0.1	0.4	0.3	0.9	0.1	-0.3	0.4	-0.3	0.9
Body fat percentage	0.2	0.8	3.0	-1.7	1.0	0.7	0.1	-0.3	1.1	-0.5	0.7	-0.3	-1.0	1.0
Leg fat percentage (right)	0.2	0.8	2.8	-1.7	-0.1	1.1	0.2	0.6	1.3	-0.5	0.9	-0.3	-0.9	1.2
Comparative body size at age 10	0.2	0.4	4.2	0.3	-2.1	0.1	0.0	0.1	0.0	-0.0	0.6	0.1	0.4	-0.0
Worry too long after embarrassment	0.2	0.3	1.7	-0.4	0.3	-0.6	0.3	0.3	-0.5	-0.4	-1.3	-0.4	0.3	-0.4
Long-standing illness, disability or infirmity	0.2	0.2	0.7	-0.4	-0.3	-0.3	0.8	0.7	-0.5	0.2	0.2	0.7	-0.2	-0.5
Medication: Gliclazide	0.2	0.3	0.8	-0.8	-0.2	0.9	-0.4	0.9	-0.1	-0.3	0.2	-0.4	-0.2	-0.1
Number of self-reported non-cancer illnesses	0.2	0.3	1.2	-0.8	1.1	0.3	0.0	0.0	0.2	-0.5	0.7	0.2	-0.8	0.1
Leg fat percentage (left)	0.2	0.8	3.9	-2.0	0.1	1.1	-0.1	0.3	0.8	-0.5	1.0	-0.4	-0.9	0.7
Blood Eosinophil Count	0.1	0.8	2.5	-1.1	1.1	1.6	-0.5	0.6	-1.2	0.2	0.3	0.4	0.5	-1.2
Blood Red Count	0.1	1.4	7.9	-1.5	0.5	2.8	-0.7	0.5	0.2	-0.2	1.8	0.4	0.9	0.2
High blood pressure	0.1	0.2	0.7	-0.6	-0.4	0.0	-0.7	-0.4	0.2	-0.8	-0.5	0.3	-0.1	-0.0
Allergy	0.1	0.3	1.2	-0.2	-0.9	1.1	0.4	0.3	-0.0	0.1	0.5	0.7	0.8	0.1
Illnesses of siblings	0.1	0.2	0.6	-0.5	0.7	0.7	-0.0	0.4	-0.4	0.4	-0.4	0.4	0.2	-0.4
Medication: Lansoprazole	0.1	0.1	0.2	-0.2	0.3	-0.2	0.3	-0.4	0.2	-0.3	-0.4	0.1	-0.3	0.1
Medication: Blood pressure	0.1	0.3	1.8	-1.3	0.2	0.1	-0.0	-0.3	0.3	-0.2	-0.1	0.8	-0.2	0.4
Pulse rate, automated reading	0.1	0.3	0.7	0.4	-0.8	-0.6	-0.2	-0.8	0.6	-0.6	0.7	-0.6	0.0	0.5
Hypertension (Self-reported)	0.1	0.2	0.6	-0.2	-0.6	0.1	-0.5	-0.8	0.1	-0.7	-0.2	0.6	0.2	0.0
Diabetes diagnosed by doctor	0.1	0.2	1.3	-1.1	-0.2	0.3	0.1	-0.1	-0.7	-0.1	-0.0	0.5	0.2	-0.7
Pain type(s) experienced in last month: Hip pain	0.1	0.1	0.4	0.0	-0.2	0.0	-0.5	0.0	-0.0	-0.3	-0.6	-0.3	-0.1	-0.2
Vascular/heart problems diagnosed by doctor	0.1	0.2	0.7	0.3	0.5	0.1	0.7	0.7	-0.1	0.9	-0.1	-0.5	0.1	0.1
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Hair Pigment	0.0	1.1	3.6	-0.7	-1.3	-1.6	-0.5	-0.5	0.3	-0.9	-1.2	-0.7	-1.9	0.3

Hub : Genes

GOLM1

Models

Trait associations