Hub : Genes

GPAA1

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0290	0.0130	5.4e-03	0.038	0.021	0.012	0.020	0.027	1.8e-05	1.0e-03	1.1e-02	1.6e-03	2.6e-04
2	GTEx	Colon Sigmoid	0.1460	0.0640	2.2e-03	0.067	NA	0.046	NA	0.043	2.3e-03	NA	1.0e-02	NA	1.2e-02
3	GTEx	Esophagus Muscularis	0.1350	0.0500	2.5e-04	0.058	NA	0.087	NA	0.118	2.1e-04	NA	5.8e-06	NA	1.2e-07
4	GTEx	Skin Sun Exposed Lower leg	0.1290	0.0390	1.8e-06	0.126	NA	0.125	NA	0.128	1.3e-10	NA	1.7e-10	NA	9.5e-11
5	GTEx	Testis	0.1090	0.0500	6.3e-03	0.087	NA	0.057	NA	0.059	1.1e-04	NA	1.6e-03	NA	1.3e-03
6	ROSMAP	Brain Pre-frontal Cortex	0.0437	0.0151	1.6e-05	0.057	0.036	0.042	0.042	0.049	7.2e-08	1.8e-05	3.2e-06	3.6e-06	6.7e-07
7	TCGA	Brain Lower Grade Glioma	0.0200	0.0147	1.1e-03	0.027	0.024	0.021	NA	0.024	4.1e-04	8.2e-04	1.8e-03	NA	8.2e-04
8	TCGA	Lung Squamous Cell Carcinoma	0.0263	0.0177	4.5e-04	0.011	0.024	0.016	NA	0.010	1.9e-02	8.7e-04	5.6e-03	NA	2.3e-02

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	0.7	1.1	4.0	0.3	2.0	1.9	-0.3	0.3	0.5	0.4	-0.4
Bipolar Disorder or Schizophrenia	0.4	0.9	4.4	0.2	1.5	2.1	-0.3	0.2	0.2	0.1	-0.1
Depressed Affect (Nagel 2018)	0.1	0.3	0.7	-0.5	-0.6	-0.8	0.4	-0.2	-0.5	-0.5	0.4
Depression (Nagel 2018)	0.6	0.8	1.2	1.0	1.1	0.7	-0.9	0.9	1.0	1.0	-0.8
Intelligence (Savage-Jansen 2018)	5.3	16.4	23.5	-4.5	3.4	-0.7	4.1	-4.0	-4.6	-4.8	4.6
Neuroticism (Nagel 2018)	0.8	1.9	3.8	-1.4	-0.5	-1.9	1.3	-1.2	-1.3	-1.6	1.5
Schizophrenia (2018)	0.1	0.2	1.4	0.0	0.7	1.2	-0.1	0.1	-0.1	-0.1	0.2
Schizophrenia vs Biploar Disorder	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Worry (Nagel 2018)	0.2	0.5	1.1	-0.7	-0.1	-1.1	0.5	-0.4	-0.6	-0.9	0.9
Alzheimer’s Disease (in mother)	0.1	0.1	0.6	0.3	0.8	-0.4	-0.2	0.1	0.2	0.4	-0.2
Alzheimer’s Disease (in father)	0.3	0.3	0.6	0.5	0.1	0.8	-0.4	0.5	0.6	0.6	-0.8
Alzheimer’s Disease (including proxy)	0.6	0.8	1.2	0.9	1.1	0.3	-0.8	0.8	0.9	1.1	-1.0
Crohns Disease (2017)	0.8	1.7	3.8	1.9	0.8	1.4	-0.6	0.6	1.1	1.7	-1.6
Irritable Bowel Disease (IBD)	0.7	1.8	3.0	1.6	1.7	1.7	-0.5	0.5	1.1	1.5	-1.3
Ulcerative Colitis (UC)	0.4	0.8	4.0	-0.0	2.0	1.6	0.1	-0.1	0.2	0.1	-0.2
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Reaction Time	0.1	0.2	0.4	0.4	0.6	-0.2	-0.0	0.0	0.2	0.5	-0.7
Verbal and Numeric Reasoning (VNR)	4.5	10.7	16.4	-4.0	1.1	-1.0	3.2	-3.1	-4.0	-4.1	3.8
Breast Cancer	0.1	0.2	0.5	0.3	-0.5	0.7	-0.5	0.2	0.5	0.5	-0.2
Ovarian Cancer	0.2	0.3	1.6	-0.4	-1.3	-0.2	0.3	-0.3	-0.4	-0.4	0.5
Prostate Cancer	2.4	3.4	4.9	-1.8	1.7	-0.9	2.2	-2.2	-1.8	-2.0	1.9
Age at First Birth	0.1	0.1	0.4	0.1	0.6	-0.4	-0.1	0.0	0.0	0.1	-0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	0.1	0.1	0.4	-0.5	0.0	0.0	0.0	0.0	-0.6	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0
Crohns Disease (2012)	0.6	1.0	2.1	-1.2	1.4	-1.2	1.2	-1.3	0.0	0.0	0.0
Mean Putamen Volume	0.7	0.8	1.1	-0.7	-0.6	0.9	1.0	-1.0	-0.9	-0.9	0.9
Fasting Glucose	3.3	4.0	6.1	-2.0	-1.2	-0.3	2.2	-2.3	-2.1	-2.3	2.5
HbA1C	0.1	0.2	0.4	0.5	0.7	0.0	-0.5	0.4	0.3	0.3	-0.1
HDL Cholesterol	0.4	0.6	1.0	0.9	-1.0	0.8	-1.0	0.9	1.0	0.0	0.0
LDL Cholesterol	3.0	4.7	24.9	1.1	5.0	2.7	-1.2	1.2	1.2	0.0	0.0
Lupus	0.3	0.5	2.5	-0.2	1.6	-0.3	0.1	-0.1	-0.1	-0.7	0.8
Neuroticism (2016)	0.3	0.5	2.3	-0.7	0.3	1.5	0.1	-0.0	-0.3	-0.7	0.6
Primary Biliary Cirrhosis	0.0	0.0	0.0	0.0	-0.2	0.0	0.0	0.0	0.0	0.0	0.0
Rheumatoid Arthritis	0.2	0.2	1.8	-0.2	-0.4	-1.3	0.0	-0.0	-0.2	0.0	0.0
Schizophrenia (2014)	0.2	0.5	1.3	-0.6	-1.2	0.1	0.5	-0.5	-0.6	-0.7	0.7
Triglycerides	0.1	0.1	0.3	-0.1	-0.4	-0.0	0.6	-0.5	-0.2	0.0	0.0
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Ulcerative Colitis	0.6	0.8	4.8	0.5	2.2	0.8	-0.5	0.4	0.7	0.0	0.0
Blood Eosinophil Count	2.8	21.6	25.4	4.9	3.2	4.6	-4.7	4.7	5.0	5.0	-4.9
Blood Platelet Count	10.8	125.6	349.7	9.2	18.7	11.4	-9.5	9.6	9.0	9.4	-9.4
Blood Red Count	2.0	19.0	22.2	-4.4	-4.7	-4.7	4.1	-4.1	-4.4	-4.3	4.2
Blood White Count	1.3	9.8	13.1	3.6	1.6	2.0	-3.3	3.2	3.6	3.5	-3.5
Heel T-Score	0.0	0.2	0.9	-0.4	1.0	-0.6	0.3	-0.2	-0.4	-0.2	0.0
BMI	0.8	4.7	7.0	2.6	1.4	0.2	-2.5	2.5	2.7	2.4	-2.1
Height	2.6	49.8	104.0	-5.8	-10.2	-7.8	6.0	-6.1	-5.7	-6.7	7.0
Waist Hip Ratio (WHR)	3.8	16.9	20.1	-4.4	-3.5	-3.4	4.2	-4.2	-4.4	-4.5	4.2
Systolic Blood Pressure	0.8	4.2	12.7	-2.1	-3.6	-0.5	1.8	-1.7	-2.1	-1.8	1.6
Smoking Status	0.5	1.1	1.7	-0.8	1.0	-1.0	1.3	-1.3	-1.1	-1.0	1.0
Allergy or Eczema	0.1	0.3	0.6	-0.7	-0.2	0.5	0.4	-0.4	-0.8	-0.5	0.5
Cardiovascular Disease	0.5	1.7	3.2	-1.8	-0.0	0.3	1.6	-1.5	-1.6	-1.5	1.1
Hypothyroidism (self reported)	0.0	0.1	0.2	0.1	0.1	0.4	0.2	-0.3	0.2	-0.2	0.3
Respiratory disease	0.0	0.1	0.2	0.4	-0.3	0.0	0.2	-0.2	0.5	0.3	-0.2
Type 2 Diabetes (T2D) (2018)	1.4	2.6	3.8	-1.5	-1.7	-0.4	1.9	-1.9	-1.6	-1.7	1.7
Lung FEV1/FVC ratio	0.1	0.5	2.9	0.5	0.4	1.7	-0.4	0.4	0.7	0.3	-0.4
Lung FVC	1.0	4.9	8.8	2.4	0.5	0.2	-2.3	2.3	2.4	2.9	-3.0
Neuroticism	0.0	0.1	0.2	-0.3	-0.3	-0.4	-0.1	0.2	-0.2	-0.3	0.2
Chronotype (morning person)	0.5	1.2	5.0	0.6	2.2	1.1	-1.0	0.9	0.7	0.7	-0.7
Hair Pigment	0.0	0.9	4.3	0.3	2.1	1.1	-0.6	0.6	0.4	0.4	-0.5
Tanning	0.2	2.0	13.9	0.1	-3.7	-1.4	0.2	-0.2	0.2	0.1	0.1
Hand grip strength (left)	0.4	1.0	3.8	-0.6	-2.0	-0.5	0.8	-0.9	-0.9	-0.7	0.8
Number of treatments/medications taken	1.6	2.9	9.2	1.2	1.2	3.0	-1.4	1.4	1.4	1.5	-1.8
Average weekly spirits intake	1.8	2.2	2.9	1.5	-0.3	1.6	-1.5	1.4	1.7	1.7	-1.7
Sensitivity / hurt feelings	0.1	0.1	0.8	0.0	0.2	-0.9	0.2	-0.1	-0.1	0.0	0.0
Frequency of depressed mood in last 2 weeks	0.1	0.2	0.8	0.4	0.9	-0.2	-0.2	0.2	0.5	0.4	-0.4
Hearing difficulty/problems: Yes	4.2	6.4	9.7	-2.9	-0.6	-1.2	2.7	-2.6	-2.9	-3.1	3.1
Relative age of first facial hair	2.7	5.5	11.7	-2.3	-1.5	-3.4	2.1	-2.0	-2.0	-2.7	2.4
Other serious medical condition/disability diagnosed by doctor	5.0	6.5	10.2	3.0	-0.1	0.7	-2.7	2.6	3.2	3.1	-3.1
Ever used hormone-replacement therapy (HRT)	3.8	4.9	6.5	2.4	1.4	2.3	-2.3	2.2	2.5	2.2	-2.1
Ever had hysterectomy (womb removed)	4.1	4.6	6.7	-2.4	-1.0	-1.6	2.1	-2.1	-2.4	-2.6	2.5
Systolic blood pressure, automated reading	0.2	0.5	2.7	-0.7	-1.6	-0.4	0.4	-0.3	-0.7	-0.4	0.4
Eye problems/disorders: Diabetes related eye disease	0.3	0.4	1.6	-0.1	1.3	1.1	-0.0	0.0	-0.0	-0.2	0.2
Angina	0.9	1.1	4.2	0.9	-0.0	2.0	-0.8	0.8	1.1	0.8	-1.1
Medication for hormone replacement therapy	3.4	3.8	5.2	2.1	0.6	1.8	-2.0	2.0	2.3	2.3	-2.1
Vitamin and mineral supplements	2.1	2.8	3.8	1.8	1.4	-0.0	-1.8	1.8	1.9	2.0	-1.9
Supplements: Zinc	1.1	1.2	1.9	-1.3	0.3	-0.8	1.0	-1.0	-1.3	-1.4	1.1
Medication: Co-codamol	0.5	0.6	1.0	0.4	0.8	-0.6	-1.0	1.0	0.7	0.7	-0.7
Medication: Metformin	0.6	0.8	2.8	-0.6	-1.7	0.1	0.9	-0.9	-0.6	-0.8	0.8
Diabetes (father)	0.3	0.4	1.9	-0.6	-1.4	-0.1	0.4	-0.4	-0.5	-0.6	0.4
Diabetes (mother)	1.1	1.4	1.9	1.3	-1.1	0.7	-1.3	1.3	1.0	1.2	-1.4
Severe depression (siblings)	0.6	0.7	2.7	-0.9	1.6	-0.3	0.6	-0.6	-0.7	-0.7	0.7
Pack years adult smoking proportion	0.5	0.8	4.0	-0.7	-0.1	-2.0	0.1	-0.1	-0.6	-0.8	0.7
Impedance of leg (right)	1.1	5.1	7.0	-2.6	-1.1	-1.0	2.5	-2.5	-2.5	-2.6	2.5
Leg fat-free mass (left)	0.3	1.7	7.2	-0.3	-2.7	-2.3	-0.1	0.0	-0.1	-0.5	0.7
Trunk fat percentage	0.3	1.1	4.7	0.5	2.2	-1.0	-0.9	0.9	0.7	0.3	-0.2
Hand grip strength (right)	1.8	4.8	6.4	-2.2	-1.1	-2.4	2.1	-2.2	-2.3	-2.4	2.5
Townsend deprivation index at recruitment	0.5	0.6	0.8	0.7	0.2	0.8	-0.9	0.9	0.8	0.9	-0.9
Current tobacco smoking	1.1	1.8	3.8	-1.1	0.7	-1.9	1.6	-1.6	-1.3	-1.2	1.1
Average weekly fortified wine intake	4.0	4.7	6.1	-2.0	-2.4	-2.5	1.9	-2.0	-1.9	-2.2	2.3
Maternal smoking around birth	1.0	1.4	4.5	-0.9	-1.4	-2.1	0.8	-0.7	-0.8	-1.1	1.0
Fed-up feelings	0.4	0.7	1.4	0.6	-1.2	-0.9	-0.8	0.9	0.8	0.8	-0.8
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.2	0.3	0.4	0.5	-0.4	-0.4	0.4	0.5	0.5	-0.5
Relative age voice broke	2.5	3.8	7.3	-1.7	-1.6	-2.7	2.0	-2.0	-1.5	-2.0	1.9
Taking other prescription medications	1.6	2.5	3.4	1.7	0.7	1.7	-1.6	1.6	1.8	1.6	-1.5
Age when periods started (menarche)	1.2	2.8	3.4	-1.8	-1.8	-1.1	1.6	-1.6	-1.8	-1.9	1.6
Bilateral oophorectomy (both ovaries removed)	0.0	0.0	0.1	0.1	-0.0	-0.3	-0.1	0.1	0.3	-0.0	-0.0
Heel bone mineral density (BMD) T-score, automated (left)	0.4	1.0	7.2	-0.3	0.0	-2.7	0.5	-0.5	-0.3	-0.1	0.0
Tinnitus: Yes, but not now, but have in the past	0.4	0.4	1.9	-0.6	-1.4	0.1	0.1	-0.0	-0.3	-0.7	0.7
Qualifications: CSEs or equivalent	0.4	0.5	1.0	0.8	-1.0	-0.1	-0.5	0.5	0.8	0.8	-0.9
Serious illness, injury or assault to yourself	1.7	2.1	5.9	1.3	2.4	1.7	-1.0	1.0	1.3	1.1	-1.2
High blood pressure	0.4	1.0	2.1	-1.4	-0.1	0.2	1.1	-1.0	-1.3	-1.2	0.8
Hayfever, allergic rhinitis or eczema	0.3	0.6	1.0	-1.0	0.2	0.5	0.7	-0.7	-1.0	-0.9	0.9
Multivitamins +/- minerals	1.8	2.3	3.6	-1.8	-0.9	-0.1	1.6	-1.5	-1.9	-1.8	1.7
Stomach or abdominal pain in last month	1.0	1.2	9.0	0.3	-3.0	-0.3	-0.1	0.2	0.2	0.4	-0.4
Supplements: Glucosamine	1.0	1.3	2.1	-1.3	1.1	0.5	0.8	-0.8	-1.4	-1.4	1.4
Diverticular disease/diverticulitis (self-reported)	0.2	0.2	0.5	0.2	-0.7	0.7	-0.5	0.4	0.4	0.2	-0.2
Medication: Atenolol	0.1	0.1	0.3	-0.5	-0.3	-0.3	-0.1	0.0	-0.3	-0.5	0.3
Medication: Levothyroxine sodium	0.1	0.1	0.3	0.2	-0.5	0.4	0.3	-0.4	0.0	-0.2	0.4
Sitting height	1.7	11.7	46.8	-2.4	-6.8	-2.7	2.5	-2.5	-2.2	-2.8	3.0
Chronic bronchitis/emphysema (father)	1.1	1.2	2.0	1.3	-0.1	0.6	-1.1	1.1	1.4	1.3	-1.3
High blood pressure (mother)	5.0	7.0	8.5	2.9	0.7	2.8	-2.7	2.8	2.7	2.8	-2.8
Body mass index (BMI)	1.0	4.2	5.3	2.2	2.2	-0.6	-2.2	2.3	2.3	2.1	-2.0
Impedance of leg (left)	1.2	5.9	7.7	-2.8	-1.4	-1.1	2.7	-2.7	-2.7	-2.7	2.7
Leg predicted mass (left)	0.3	1.7	7.6	-0.2	-2.8	-2.4	-0.1	0.1	-0.1	-0.5	0.6
Trunk fat mass	0.2	0.7	3.6	0.4	0.5	-1.9	-0.8	0.8	0.6	0.1	0.1
Waist circumference	0.2	0.7	4.0	-0.3	0.8	-2.0	-0.0	-0.0	-0.2	-0.5	0.6
Number of incorrect matches in round	2.5	4.2	5.8	2.1	0.3	1.9	-2.2	2.2	2.4	2.3	-2.3
Past tobacco smoking	0.1	0.2	1.1	-0.3	-1.1	-0.6	-0.1	0.1	-0.1	-0.1	-0.0
Alcohol usually taken with meals	0.5	0.8	3.2	0.2	1.2	1.8	-0.8	0.9	0.2	0.2	-0.2
Nervous feelings	1.2	2.3	3.4	-1.8	0.6	-1.2	1.5	-1.5	-1.7	-1.8	1.7
Frequency of tenseness / restlessness in last 2 weeks	0.7	1.1	2.1	1.1	1.0	1.1	-0.8	0.9	0.9	1.2	-1.4
Hearing difficulty/problems with background noise	2.3	3.7	5.8	-1.9	-0.0	0.1	2.3	-2.3	-2.0	-2.4	2.4
Hair/balding pattern: Pattern 2	0.2	0.3	0.8	-0.4	-0.9	0.2	0.6	-0.6	-0.3	-0.5	0.5
Had menopause	1.6	2.0	2.7	1.6	1.6	0.7	-1.2	1.2	1.6	1.7	-1.6
Had other major operations	0.1	0.1	0.4	0.3	-0.6	-0.2	0.0	-0.1	0.4	0.2	-0.1
Forced vital capacity (FVC)	0.4	1.6	6.9	-0.7	-2.6	-1.6	0.7	-0.8	-0.7	-0.7	0.9
Heel bone mineral density (BMD) T-score, automated (right)	1.5	3.5	13.7	-1.4	-0.9	-3.7	1.8	-1.8	-1.3	-1.2	1.3
Ever unenthusiastic/disinterested for a whole week	0.6	0.7	4.0	0.2	2.0	0.4	-0.5	0.6	0.4	0.5	-0.6
Qualifications: None of the above	0.5	1.0	1.1	1.0	1.0	-0.8	-1.0	1.0	0.9	1.1	-1.0
Financial difficulties in last 2 years	3.1	4.2	5.6	2.1	-0.9	1.8	-2.2	2.2	2.2	2.2	-2.4
Mouth/teeth dental problems	0.7	1.1	3.5	0.9	-1.9	1.5	-0.7	0.6	0.7	0.7	-0.5
Heart attack	0.2	0.3	0.7	0.4	-0.2	0.9	-0.4	0.4	0.7	0.5	-0.7
Allergy	0.0	0.1	0.2	0.3	0.1	0.0	-0.4	0.4	0.3	0.2	-0.3
Pain all over the body in last month	1.1	1.2	1.6	1.0	-1.2	0.8	-1.1	1.0	1.3	1.1	-1.2
Diabetes (self-reported)	1.0	1.5	2.1	-1.1	-1.4	-1.0	1.4	-1.4	-1.1	-1.2	1.2
Hayfever/allergic rhinitis (self-reported)	0.5	0.6	0.8	0.6	-0.9	0.9	-0.8	0.8	0.8	0.8	-0.8
Medication: Ramipril	0.4	0.5	2.5	-0.5	0.6	1.6	0.0	0.2	-0.3	-0.6	0.4
Medication: Simvastatin	0.8	1.2	8.0	-0.3	2.8	1.0	0.5	-0.5	-0.2	-0.4	0.3
Fluid intelligence score	3.4	7.1	11.4	-3.4	0.7	-0.6	2.6	-2.5	-3.3	-3.3	3.1
Illnesses of siblings	0.4	0.5	1.4	-0.3	-0.1	-0.4	1.1	-1.2	-0.5	-0.7	0.8
Neuroticism score	0.3	0.5	1.4	-0.8	-0.5	-1.2	0.5	-0.4	-0.8	-0.7	0.6
Weight	0.3	1.3	6.7	0.0	-1.7	-2.6	-0.2	0.2	0.2	-0.3	0.5
Impedance of arm (right)	0.6	2.7	9.8	-1.4	3.1	1.7	0.9	-0.8	-1.3	-1.4	1.4
Arm fat percentage (right)	1.3	5.2	17.3	2.0	4.2	-0.2	-2.3	2.3	2.1	1.8	-1.6
Trunk fat-free mass	1.4	8.1	34.1	-1.4	-5.8	-4.0	1.4	-1.5	-1.4	-1.7	1.9
Hip circumference	0.3	1.3	4.4	0.9	2.1	-0.8	-1.1	1.1	1.1	0.6	-0.3
Time employed in main current job	0.5	0.6	1.6	0.7	-0.4	1.3	-0.7	0.8	0.6	0.8	-0.6
Alcohol intake versus 10 years previously	0.6	0.9	2.0	0.9	0.0	1.4	-0.7	0.7	0.9	1.0	-1.2
Father’s age at death	0.4	0.5	0.9	0.9	0.8	0.1	-0.7	0.6	0.7	0.9	-0.8
Worrier / anxious feelings	0.2	0.4	3.0	0.0	-1.7	-0.6	0.0	0.1	0.1	0.2	-0.2
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.1	0.3	-0.5	0.4	-0.2	0.4	-0.3	-0.3	-0.3	0.2
Falls in the last year	0.7	1.0	7.1	-0.1	2.7	-0.6	-0.4	0.5	0.2	-0.0	-0.1
Hair/balding pattern: Pattern 3	0.1	0.1	0.2	0.3	0.1	-0.4	-0.4	0.4	0.1	0.3	-0.4
Number of live births	1.9	2.7	4.7	1.5	-2.2	-1.8	-1.4	1.4	1.3	1.7	-1.8
Forced expiratory volume in 1-second (FEV1)	0.1	0.4	3.2	-0.2	-1.8	-0.2	0.1	-0.0	-0.1	-0.2	0.2
Pulse rate	0.6	0.9	1.5	1.1	1.2	0.5	-0.9	0.8	1.2	1.0	-0.9
Happiness	0.1	0.1	0.2	0.2	-0.2	0.3	-0.3	0.4	0.3	0.5	-0.5
Noisy workplace	0.7	0.9	3.3	0.8	1.8	1.2	-0.5	0.6	0.5	0.6	-0.5
Qualifications: A levels/AS levels or equivalent	3.2	7.1	10.6	-3.3	-0.3	-0.5	2.9	-2.9	-3.2	-3.1	3.0
Serious illness, injury or assault of a close relative in last 2 years	0.7	0.8	1.9	-0.9	1.4	0.2	0.9	-0.8	-0.9	-0.8	1.1
Mouth/teeth dental problems: Dentures	0.1	0.1	0.3	0.2	0.5	-0.5	-0.2	0.2	0.2	0.4	-0.5
Asthma	0.3	0.6	1.1	1.0	-0.8	0.6	-0.4	0.3	1.1	0.9	-0.7
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.6	3.9	0.0	-2.0	-0.8	-0.0	0.0	-0.1	0.1	-0.3
Medication: Cholesterol lowering	3.7	5.7	19.4	1.7	4.4	3.2	-1.3	1.4	1.8	1.7	-1.8
Depression (self-reported)	0.2	0.3	0.4	-0.5	0.6	0.6	0.4	-0.4	-0.7	-0.5	0.5
Medication: Lansoprazole	0.6	0.7	1.6	-0.8	1.2	-0.1	0.9	-1.0	-0.6	-0.8	0.7
Prospective memory result	0.9	1.1	1.6	1.1	0.9	0.2	-1.0	0.9	1.2	1.3	-1.3
Lung cancer (father)	0.1	0.1	0.4	-0.0	0.4	0.6	0.1	-0.1	-0.1	0.0	-0.2
Illnesses of mother	1.5	1.9	3.0	-1.4	-0.4	-1.3	1.7	-1.7	-1.0	-1.4	1.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	0.8	5.0	0.1	-2.2	-1.1	-0.4	0.4	0.2	0.1	-0.2
Pulse wave Arterial Stiffness index	0.8	0.9	3.0	0.9	1.7	-0.2	-0.8	0.8	0.8	0.9	-0.9
Impedance of arm (left)	0.5	2.5	8.6	-1.3	2.9	1.8	0.8	-0.7	-1.2	-1.4	1.4
Arm fat mass (right)	0.4	1.8	2.9	1.3	1.7	-1.4	-1.5	1.5	1.4	1.1	-0.9
Trunk predicted mass	1.3	7.4	32.1	-1.3	-5.7	-3.8	1.3	-1.3	-1.2	-1.6	1.8
Standing height	2.8	28.2	75.9	-4.4	-8.7	-4.8	4.1	-4.2	-4.3	-5.0	5.3
Length of working week for main job	1.0	1.1	2.6	1.0	-0.0	1.6	-1.0	1.1	1.0	1.0	-1.0
Exposure to tobacco smoke at home	3.6	4.0	6.1	1.9	0.3	1.2	-2.5	2.5	2.1	2.3	-2.2
Breastfed as a baby	1.3	1.6	4.5	-0.9	2.1	-0.8	1.3	-1.3	-1.0	-1.0	1.3
Tense / ‘highly strung’	1.6	2.6	7.5	-1.4	-0.4	-2.7	1.6	-1.5	-1.4	-1.5	1.4
Seen doctor (GP) for nerves, anxiety, tension or depression	1.3	2.0	5.2	-1.2	2.3	0.7	1.5	-1.5	-1.3	-1.2	1.1
Hair/balding pattern: Pattern 4	2.2	5.4	7.5	2.6	-0.0	2.1	-2.7	2.7	2.6	2.4	-2.3
Birth weight of first child	1.5	2.6	5.0	-1.6	-0.4	-2.2	1.4	-1.5	-1.8	-1.8	1.8
Peak expiratory flow (PEF)	0.1	0.2	0.5	-0.4	-0.7	-0.3	0.4	-0.4	-0.1	-0.4	0.5
Pulse wave reflection index	0.3	0.3	1.5	-0.4	1.2	0.0	0.4	-0.4	-0.5	-0.5	0.4
Ever highly irritable/argumentative for 2 days	0.1	0.1	0.3	0.0	0.4	-0.6	0.0	0.1	0.1	0.1	-0.3
Loud music exposure frequency	0.2	0.2	0.9	-0.3	-0.3	-1.0	-0.2	0.1	-0.3	-0.2	0.2
Qualifications: O levels/GCSEs or equivalent	1.2	1.9	3.1	-1.8	-1.2	-0.6	1.2	-1.2	-1.7	-1.6	1.4
Mouth/teeth dental problems: Bleeding gums	0.6	0.7	5.4	-0.3	2.3	-0.4	-0.0	0.1	0.0	-0.4	0.3
Blood clot in the leg (DVT)	1.5	1.9	3.2	1.3	-0.7	0.4	-1.7	1.8	1.5	1.5	-1.5
Medication: Paracetamol	0.1	0.1	0.6	-0.1	0.6	-0.7	-0.0	-0.0	0.1	-0.2	0.1
Headache pain in last month	0.0	0.0	0.1	0.0	0.3	-0.3	0.2	-0.2	-0.2	-0.2	0.3
Medication for cholesterol, blood pressure or diabetes	0.5	0.9	4.9	0.1	-1.4	-2.2	-0.0	-0.1	0.0	-0.1	0.3
Glaucoma (self-reported)	0.3	0.3	1.8	0.1	1.3	0.8	0.1	-0.0	0.3	0.3	-0.5
Gout (self-reported)	0.3	0.4	0.7	-0.7	-0.4	-0.7	0.8	-0.9	-0.6	-0.5	0.6
Hypothyroidism/myxoedema (self-reported)	0.1	0.3	0.8	0.5	-0.9	0.8	-0.2	0.1	0.5	0.3	-0.0
Medication: Amlodipine	0.8	1.1	1.8	-1.3	-0.5	-0.0	1.3	-1.3	-1.1	-1.2	1.0
Medication: Ventolin 100micrograms inhaler	0.4	0.6	3.1	-0.1	-1.8	0.9	0.5	-0.6	0.0	-0.1	0.3
Birth weight	2.0	4.3	6.2	-2.0	2.5	-0.4	2.4	-2.4	-1.9	-2.1	2.2
Chronic bronchitis/emphysema (mother)	0.1	0.2	0.4	-0.5	-0.1	-0.4	0.2	-0.2	-0.4	-0.5	0.7
High blood pressure (siblings)	0.6	0.9	1.7	0.8	-0.4	0.9	-1.3	1.3	0.9	0.9	-0.9
Forced vital capacity (FVC), Best measure	0.5	1.7	8.6	-0.2	-2.9	-2.2	-0.0	0.0	-0.2	-0.2	0.2
Body fat percentage	0.4	1.7	7.0	0.9	2.6	-1.0	-1.2	1.2	1.1	0.7	-0.6
Leg fat percentage (right)	0.5	1.7	6.0	1.0	2.5	-1.3	-1.1	1.1	1.1	0.9	-0.7
Arm fat-free mass (right)	1.4	7.3	31.7	-1.3	-5.6	-3.9	1.4	-1.4	-1.2	-1.5	1.7
Exposure to tobacco smoke outside home	0.2	0.3	1.6	0.0	-1.3	-0.7	-0.3	0.4	0.3	0.2	-0.2
Comparative body size at age 10	0.1	0.2	0.3	-0.1	0.5	-0.3	-0.6	0.6	0.1	-0.2	0.4
Number of full brothers	0.2	0.2	1.5	0.2	-1.2	-0.2	0.0	-0.0	0.3	0.1	-0.4
Worry too long after embarrassment	2.1	3.6	4.8	-2.2	-0.9	-1.8	2.2	-2.1	-2.0	-1.9	1.7
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.7	2.0	-0.7	1.4	0.6	0.9	-0.8	-0.7	-0.8	0.7
Wheeze or whistling in the chest in last year	0.0	0.1	0.1	0.0	-0.4	0.1	0.2	-0.3	0.3	-0.1	0.3
Number of children fathered	0.6	0.7	2.1	0.8	1.4	0.9	-0.5	0.5	0.7	0.7	-0.6
Reason for reducing amount of alcohol drunk: Health precaution	0.9	1.0	1.4	-0.8	-1.0	-0.9	1.1	-1.1	-0.8	-1.1	1.2
Age at first live birth	0.8	1.4	3.1	-1.2	1.7	0.8	1.1	-1.1	-1.4	-1.1	0.9
Pulse wave peak to peak time	1.2	1.4	5.0	-1.1	-2.2	-0.0	0.9	-0.9	-1.0	-1.1	1.1
Health satisfaction	0.0	0.1	0.1	-0.3	-0.3	0.1	0.2	-0.1	-0.4	-0.2	0.0
Shortness of breath walking on level ground	1.1	1.3	1.8	-1.1	1.3	-0.8	1.1	-1.1	-1.2	-1.3	1.2
Qualifications: College or University degree	1.0	3.0	4.3	-2.0	-2.1	-0.1	1.6	-1.5	-1.9	-1.9	1.9
Eye problems/disorders: None of the above	1.5	1.8	2.3	1.3	-1.5	1.3	-1.2	1.3	1.2	1.5	-1.3
Mouth/teeth dental problems: Loose teeth	1.2	1.4	2.5	1.5	0.0	-1.1	-1.1	1.1	1.6	1.4	-1.1
Emphysema/chronic bronchitis	2.4	2.7	4.3	-1.5	-0.2	-2.1	1.8	-1.9	-1.6	-1.7	1.6
Medication for pain relief, constipation, heartburn	0.7	1.2	2.8	-0.8	0.0	-1.7	1.2	-1.2	-0.9	-1.0	1.3
Neck or shoulder pain in last month	0.2	0.3	0.7	0.3	-0.8	-0.0	-0.4	0.5	0.5	0.6	-0.8
Medication: Blood pressure	0.5	0.9	4.0	-0.6	-2.0	1.3	0.4	-0.3	-0.5	-0.5	0.4
Angina (self-reported)	1.0	1.3	4.2	1.0	-0.3	2.0	-0.9	1.0	1.2	0.9	-1.2
Migraine (self-reported)	0.3	0.3	0.4	0.6	0.6	0.4	-0.6	0.7	0.6	0.6	-0.5
Medication: Ibuprofen	0.7	0.8	1.9	0.7	-1.4	-0.3	-0.8	0.8	0.6	0.9	-1.2
Medication: Allopurinol	0.8	1.1	2.2	-0.7	-1.2	-1.5	1.2	-1.3	-0.8	-0.7	0.7
Medication: Omeprazole	1.2	1.5	2.2	1.1	0.3	1.5	-1.5	1.5	1.2	1.1	-1.2
Medication: Seretide 50 evohaler	0.3	0.3	1.7	0.0	1.3	0.9	0.1	-0.1	-0.0	-0.2	0.1
Mean time to correctly identify matches	0.1	0.2	0.8	0.3	0.9	-0.3	0.1	-0.1	0.1	0.4	-0.5
Heart disease (mother)	0.1	0.1	0.8	-0.2	-0.1	0.9	-0.2	0.3	-0.3	0.0	-0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.0	1.2	3.7	-0.9	1.9	0.7	1.0	-1.1	-0.8	-0.8	0.8
Whole body fat mass	0.2	0.9	4.0	0.7	0.5	-2.0	-0.9	0.9	0.9	0.4	-0.2
Leg fat mass (right)	0.3	1.0	4.3	0.6	0.6	-2.1	-0.9	0.9	0.8	0.5	-0.3
Arm predicted mass (right)	1.4	7.2	31.0	-1.1	-5.6	-4.0	1.3	-1.3	-1.1	-1.4	1.7
Pulse rate, automated reading	0.4	1.2	6.2	-0.4	-2.5	-1.4	0.7	-0.8	-0.3	-0.4	0.6
Alcohol intake frequency.	0.2	0.4	2.4	0.0	1.6	0.3	-0.2	0.3	-0.1	0.2	-0.3
Comparative height size at age 10	2.0	10.8	38.2	-2.7	-6.2	-1.7	2.3	-2.4	-2.6	-3.0	3.3
Number of full sisters	0.2	0.2	0.8	-0.3	0.0	-0.9	0.4	-0.5	-0.3	-0.3	0.4
Suffer from ‘nerves’	0.2	0.4	2.4	0.2	1.6	0.6	-0.2	0.2	0.3	0.1	-0.1
Overall health rating	0.4	0.8	1.6	0.8	-0.0	-1.0	-0.6	0.7	1.0	1.1	-1.3
Chest pain or discomfort	0.9	1.4	1.9	-0.9	-1.2	-1.4	1.3	-1.3	-1.0	-1.1	1.0
Had major operations	2.2	2.6	4.1	1.7	0.4	0.5	-1.9	2.0	1.6	1.8	-1.9
Age at last live birth	0.7	1.0	2.0	-1.3	0.5	0.1	1.1	-1.0	-1.4	-1.1	0.8
Family relationship satisfaction	0.1	0.1	0.3	-0.0	-0.4	-0.1	0.5	-0.4	-0.1	-0.2	0.4
Leg pain on walking	0.7	0.9	4.2	0.4	2.1	0.7	-0.9	0.9	0.5	0.5	-0.7
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	1.0	0.5	0.4	-0.3	-0.9	1.0	0.6	0.8	-0.7
Commuting to job workplace: Car/motor vehicle	0.9	1.1	6.6	0.4	2.6	0.3	-0.5	0.6	0.4	0.6	-0.7
Illness, injury, bereavement, stress in last 2 years	0.6	0.8	4.9	-0.6	-2.2	-0.3	0.4	-0.4	-0.5	-0.4	0.4
Medication: Aspirin	0.8	1.0	4.9	0.2	0.9	2.2	-0.6	0.7	0.7	0.5	-0.8
Supplements: Vitamin C	3.9	4.6	6.2	-2.2	-1.7	-0.8	2.4	-2.5	-2.3	-2.4	2.4
Knee pain experienced in last month	1.0	1.5	8.0	-0.2	-1.6	-2.8	0.7	-0.8	-0.4	-0.3	0.2
Hypertension (Self-reported)	0.4	1.2	2.3	-1.5	-0.4	0.1	1.2	-1.1	-1.4	-1.2	0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.5	1.0	0.5	0.5	0.2	-1.0	1.0	0.6	0.7	-0.8
Illnesses of father: Heart disease	0.2	0.2	1.3	-0.2	1.2	-0.1	0.3	-0.2	-0.1	-0.4	0.5
Illnesses of siblings: Diabetes	0.3	0.4	0.8	0.8	-0.3	0.8	-0.3	0.3	0.9	0.7	-0.5
Smoking status: Previous	0.3	0.4	1.4	0.6	0.9	1.2	-0.2	0.3	0.5	0.5	-0.4
Forced expiratory volume in 1-second (FEV1), predicted	0.9	1.9	9.1	-0.7	-3.0	-0.6	0.8	-0.9	-0.7	-1.2	1.3
Whole body fat-free mass	0.9	5.4	24.4	-0.9	-4.9	-3.5	0.8	-0.9	-0.9	-1.2	1.4
Leg fat-free mass (right)	0.4	1.9	8.7	-0.4	-3.0	-2.4	0.1	-0.1	-0.3	-0.6	0.8
Arm fat percentage (left)	1.2	5.0	16.7	1.9	4.1	-0.1	-2.2	2.3	2.0	1.7	-1.5
Average weekly red wine intake	3.0	4.4	5.7	-2.3	-1.0	-2.0	2.0	-2.1	-2.4	-2.4	2.4
Handedness (chirality/laterality): Left-handed	0.5	0.6	1.8	0.7	-0.3	1.4	-0.7	0.7	0.5	0.7	-0.6
Mood swings	0.1	0.2	0.6	0.5	-0.3	-0.8	-0.2	0.2	0.6	0.5	-0.6
Loneliness, isolation	0.1	0.1	0.4	-0.3	0.1	-0.2	0.6	-0.5	-0.4	-0.3	0.4
Long-standing illness, disability or infirmity	0.6	0.9	3.6	0.8	1.9	1.2	-0.3	0.4	0.8	0.7	-0.8
Ever had bowel cancer screening	0.6	0.7	2.2	1.0	0.3	1.5	-0.3	0.3	0.8	0.8	-0.9
Diabetes diagnosed by doctor	1.0	1.7	2.3	-1.2	-1.5	-0.8	1.5	-1.5	-1.2	-1.3	1.3
Ever had stillbirth, spontaneous miscarriage or termination	2.5	2.6	4.7	-1.5	-1.0	-1.5	2.1	-2.2	-1.4	-1.4	1.6
Friendships satisfaction	0.5	0.7	2.7	-0.6	-1.6	-0.3	0.5	-0.5	-0.8	-0.6	0.7
Qualifications: nursing, teaching	0.2	0.4	1.3	-0.5	0.3	1.2	0.5	-0.5	-0.5	-0.5	0.5
Commuting to job workplace: Walk	3.3	3.6	5.3	-2.2	-1.0	-0.9	1.9	-1.9	-2.1	-2.3	2.2
Eye problems/disorders: Cataract	0.5	0.6	3.1	-0.2	1.1	-1.8	0.2	-0.3	-0.2	-0.5	0.4
Mouth/teeth dental problems: Mouth ulcers	5.4	8.7	12.2	-3.5	0.3	-1.6	3.3	-3.2	-3.2	-3.5	3.4
Medication for cholesterol	0.5	0.7	2.1	-0.7	-1.4	-0.5	0.6	-0.7	-0.8	-0.8	0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.6	1.8	3.9	1.3	-0.6	2.0	-1.3	1.4	1.2	1.2	-1.4
Back pain experienced in last month	0.7	1.1	2.2	1.1	0.9	-1.0	-0.8	0.8	0.9	1.2	-1.5
Mineral and other dietary supplements	0.7	0.9	1.5	1.2	-1.0	-0.2	-0.6	0.6	1.2	1.2	-1.1
Breast cancer (self-reported)	1.0	1.2	2.1	-1.2	0.2	-0.5	1.1	-1.1	-1.2	-1.3	1.5
Asthma (self-reported)	0.2	0.4	0.7	0.8	-0.7	0.6	-0.1	0.1	0.8	0.7	-0.5
Osteoporosis (self-reported)	1.8	2.2	3.7	1.8	1.9	0.3	-1.4	1.3	1.6	1.5	-1.4
Osteoarthritis (self-reported)	0.3	0.4	2.1	-0.3	1.4	0.3	0.5	-0.5	-0.4	-0.5	0.5
Medication: Aspirin	1.6	2.0	7.5	0.8	1.1	2.7	-1.1	1.2	1.2	1.1	-1.3
Medication: Gliclazide	0.8	0.9	4.4	0.7	-0.2	2.1	-0.6	0.7	0.9	0.6	-0.5
Illnesses of father: None of the above (group 1)	0.5	0.7	1.7	-0.7	-0.7	-1.3	0.6	-0.7	-0.9	-0.6	0.6
Smoking status: Current	1.3	2.1	3.1	-1.3	0.8	-1.7	1.7	-1.8	-1.4	-1.4	1.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.5	0.7	0.5	0.6	0.4	-0.8	0.8	0.5	0.7	-0.9
Whole body water mass	0.9	5.1	23.3	-0.9	-4.8	-3.4	0.8	-0.8	-0.8	-1.2	1.4
Leg predicted mass (right)	0.3	1.8	8.6	-0.3	-2.9	-2.3	-0.0	-0.0	-0.2	-0.5	0.7
Arm fat mass (left)	0.6	2.5	3.3	1.6	1.7	-1.2	-1.8	1.8	1.7	1.4	-1.2
Number of self-reported non-cancer illnesses	0.3	0.5	1.2	0.6	0.7	0.7	-0.4	0.5	0.7	0.9	-1.1
Average weekly champagne plus white wine intake	0.7	0.9	3.6	0.7	-0.4	1.9	-0.7	0.7	0.8	0.8	-0.8
Miserableness	1.7	2.9	3.8	-1.9	-0.4	-1.4	1.8	-1.8	-2.0	-1.9	1.9
Guilty feelings	0.4	0.5	3.4	-0.1	-0.8	-1.8	0.2	-0.3	-0.2	-0.1	0.2
Wears glasses or contact lenses	0.3	0.3	0.7	-0.2	-0.7	-0.4	0.8	-0.9	-0.0	-0.5	0.6
Ever taken oral contraceptive pill	0.5	0.6	2.7	0.7	-1.6	0.3	-0.6	0.5	0.5	0.7	-0.5
Hearing aid user	0.9	1.0	5.7	0.0	1.4	2.4	-0.3	0.3	0.0	-0.1	0.1
Mother’s age at death	1.4	1.8	2.8	-1.4	-0.7	-1.7	1.1	-1.1	-1.4	-1.4	1.5
Financial situation satisfaction	0.4	0.5	2.1	0.4	-1.2	1.4	-0.3	0.3	0.4	0.3	-0.4
Tinnitus: Yes, now most or all of the time	1.1	1.3	1.6	1.1	1.1	1.2	-1.3	1.3	1.0	1.1	-1.0
Commuting to job workplace: Public transport	2.4	2.8	4.1	-1.9	-1.4	-1.4	1.4	-1.4	-1.8	-1.9	2.0
Eye problems/disorders: Glaucoma	0.5	0.6	2.5	-0.7	1.6	-0.2	0.8	-0.8	-0.4	-0.4	0.3
Medication: Blood pressure	0.1	0.2	1.1	-0.5	1.1	-0.0	0.0	0.0	-0.1	-0.2	0.1
Pain type(s) experienced in last month: Hip pain	0.3	0.4	2.1	-0.2	1.4	0.6	-0.4	0.5	-0.2	0.1	-0.4
Supplements: Fish oil (including cod liver oil)	0.3	0.4	0.8	-0.8	0.4	0.0	0.4	-0.4	-0.9	-0.8	0.6
High cholesterol (Self-reported)	1.1	2.0	14.4	-0.2	3.8	0.9	0.5	-0.3	-0.1	-0.2	-0.0
Medication: Bendroflumethiazide	0.3	0.4	2.6	0.1	-0.8	1.6	-0.3	0.3	0.3	0.1	-0.3
Medication: Paracetamol	0.5	0.8	1.1	1.0	1.1	0.5	-0.9	0.8	1.1	0.9	-1.0
Medication: Lisinopril	0.3	0.4	1.1	0.2	-0.9	-1.0	-0.5	0.5	0.5	0.3	-0.4
Medication: Atorvastatin	1.4	1.8	12.7	-0.1	3.6	1.2	0.3	-0.2	-0.1	0.0	-0.2
Illnesses of father: High blood pressure	0.3	0.3	1.4	0.5	0.3	1.2	-0.6	0.6	0.5	0.3	-0.1
Alcohol drinker status: Never	0.4	0.4	0.9	-0.9	0.2	0.0	0.6	-0.5	-0.8	-0.8	0.9
Ever smoked	0.2	0.3	1.0	0.6	1.0	0.3	-0.3	0.3	0.3	0.6	-0.5
Basal metabolic rate	0.7	4.0	16.4	-0.8	-4.0	-3.3	0.6	-0.6	-0.7	-1.0	1.2
Leg fat percentage (left)	0.4	1.5	4.5	0.9	2.1	-1.4	-1.1	1.1	1.1	0.8	-0.7
Arm fat-free mass (left)	1.1	5.4	24.2	-0.9	-4.9	-3.6	0.9	-1.0	-0.8	-1.1	1.3
Number of operations (self-reported)	0.3	0.5	1.3	0.9	-1.1	-0.4	-0.1	0.2	0.7	0.7	-0.7
Average weekly beer plus cider intake	0.9	1.3	4.6	1.4	0.0	-2.1	-0.5	0.4	1.1	1.1	-1.0
Irritability	0.9	1.4	2.2	-1.3	-0.4	-0.9	1.3	-1.1	-1.3	-1.5	1.4
Risk taking	0.2	0.3	1.0	0.6	1.0	0.4	-0.4	0.4	0.7	0.5	-0.4
Ever had prostate specific antigen (PSA) test	1.3	1.5	5.0	0.9	1.1	2.2	-1.1	1.1	1.0	0.9	-1.0
Fractured/broken bones in last 5 years	0.0	0.0	0.1	0.1	-0.3	-0.2	0.0	-0.1	0.0	0.1	-0.1
Age started oral contraceptive pill	1.8	2.3	3.0	-1.7	0.2	-1.4	1.5	-1.5	-1.7	-1.7	1.7
Diastolic blood pressure, automated reading	0.1	0.3	0.6	0.4	-0.5	-0.4	-0.6	0.6	0.3	0.8	-0.8
Ever depressed for a whole week	1.4	1.7	5.1	0.8	2.3	2.0	-0.8	0.9	0.9	0.9	-1.0
Unable to work because of sickness or disability	0.4	0.5	2.2	-0.5	0.7	-1.5	0.5	-0.5	-0.4	-0.3	0.2
Commuting to job workplace: Cycle	0.4	0.5	0.9	-0.9	0.1	0.2	0.6	-0.6	-0.8	-0.9	1.0
Myopia	0.2	0.2	0.7	-0.6	-0.8	-0.8	0.1	-0.1	-0.3	-0.4	0.4
Vascular/heart problems diagnosed by doctor	0.2	0.5	1.3	1.1	-0.1	-0.8	-0.6	0.5	0.8	0.9	-0.5
Cholesterol lowering medication	0.5	0.7	5.1	-0.2	2.3	0.5	0.3	-0.4	-0.0	-0.3	0.2
Medication: Omeprazole (e.g. Zanprol)	1.7	2.1	3.3	1.4	0.6	1.5	-1.8	1.8	1.4	1.3	-1.4
Pain experienced in last month	0.3	0.6	1.2	-0.8	0.1	0.8	0.7	-0.7	-0.6	-0.9	1.1
Supplements: Calcium	0.3	0.4	0.5	-0.6	-0.4	-0.4	0.7	-0.7	-0.6	-0.7	0.7
Basal cell carcinoma (self-reported)	0.0	0.1	0.2	0.0	-0.1	0.4	-0.2	0.2	0.3	-0.1	0.1
Heart attack/myocardial infarction (self-reported)	0.2	0.2	0.8	0.3	0.0	0.9	-0.2	0.3	0.6	0.5	-0.6
Deep venous thrombosis (DVT) (self-reported)	1.8	2.3	3.9	1.4	-0.3	0.8	-1.9	2.0	1.6	1.6	-1.6
Heart disease (siblings)	0.1	0.2	0.3	0.0	0.5	0.3	-0.5	0.5	0.2	0.2	-0.4
Alcohol drinker status: Previous	0.1	0.2	0.3	0.3	0.2	0.0	-0.5	0.5	0.3	0.5	-0.5
Pack years of smoking	0.7	1.1	4.7	-1.0	0.1	-2.2	0.4	-0.4	-0.9	-1.0	0.9
Impedance of whole body	0.7	3.7	5.5	-2.3	1.0	0.5	2.0	-1.9	-2.2	-2.4	2.3
Leg fat mass (left)	0.3	1.1	4.4	0.7	0.5	-2.1	-1.0	1.0	0.9	0.6	-0.4
Arm predicted mass (left)	1.1	5.6	23.4	-1.0	-4.8	-3.7	1.0	-1.0	-1.0	-1.3	1.4