Hub : Genes

GPAA1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0290 0.0130 5.4e-03 0.038 0.021 0.012 0.020 0.027 1.8e-05 1.0e-03 1.1e-02 1.6e-03 2.6e-04
2 GTEx Colon Sigmoid 0.1460 0.0640 2.2e-03 0.067 NA 0.046 NA 0.043 2.3e-03 NA 1.0e-02 NA 1.2e-02
3 GTEx Esophagus Muscularis 0.1350 0.0500 2.5e-04 0.058 NA 0.087 NA 0.118 2.1e-04 NA 5.8e-06 NA 1.2e-07
4 GTEx Skin Sun Exposed Lower leg 0.1290 0.0390 1.8e-06 0.126 NA 0.125 NA 0.128 1.3e-10 NA 1.7e-10 NA 9.5e-11
5 GTEx Testis 0.1090 0.0500 6.3e-03 0.087 NA 0.057 NA 0.059 1.1e-04 NA 1.6e-03 NA 1.3e-03
6 ROSMAP Brain Pre-frontal Cortex 0.0437 0.0151 1.6e-05 0.057 0.036 0.042 0.042 0.049 7.2e-08 1.8e-05 3.2e-06 3.6e-06 6.7e-07
7 TCGA Brain Lower Grade Glioma 0.0200 0.0147 1.1e-03 0.027 0.024 0.021 NA 0.024 4.1e-04 8.2e-04 1.8e-03 NA 8.2e-04
8 TCGA Lung Squamous Cell Carcinoma 0.0263 0.0177 4.5e-04 0.011 0.024 0.016 NA 0.010 1.9e-02 8.7e-04 5.6e-03 NA 2.3e-02

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.7 1.1 4.0 0.3 2.0 1.9 -0.3 0.3 0.5 0.4 -0.4
Bipolar Disorder or Schizophrenia 0.4 0.9 4.4 0.2 1.5 2.1 -0.3 0.2 0.2 0.1 -0.1
Depressed Affect (Nagel 2018) 0.1 0.3 0.7 -0.5 -0.6 -0.8 0.4 -0.2 -0.5 -0.5 0.4
Depression (Nagel 2018) 0.6 0.8 1.2 1.0 1.1 0.7 -0.9 0.9 1.0 1.0 -0.8
Intelligence (Savage-Jansen 2018) 5.3 16.4 23.5 -4.5 3.4 -0.7 4.1 -4.0 -4.6 -4.8 4.6
Neuroticism (Nagel 2018) 0.8 1.9 3.8 -1.4 -0.5 -1.9 1.3 -1.2 -1.3 -1.6 1.5
Schizophrenia (2018) 0.1 0.2 1.4 0.0 0.7 1.2 -0.1 0.1 -0.1 -0.1 0.2
Schizophrenia vs Biploar Disorder 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Worry (Nagel 2018) 0.2 0.5 1.1 -0.7 -0.1 -1.1 0.5 -0.4 -0.6 -0.9 0.9
Alzheimer’s Disease (in mother) 0.1 0.1 0.6 0.3 0.8 -0.4 -0.2 0.1 0.2 0.4 -0.2
Alzheimer’s Disease (in father) 0.3 0.3 0.6 0.5 0.1 0.8 -0.4 0.5 0.6 0.6 -0.8
Alzheimer’s Disease (including proxy) 0.6 0.8 1.2 0.9 1.1 0.3 -0.8 0.8 0.9 1.1 -1.0
Crohns Disease (2017) 0.8 1.7 3.8 1.9 0.8 1.4 -0.6 0.6 1.1 1.7 -1.6
Irritable Bowel Disease (IBD) 0.7 1.8 3.0 1.6 1.7 1.7 -0.5 0.5 1.1 1.5 -1.3
Ulcerative Colitis (UC) 0.4 0.8 4.0 -0.0 2.0 1.6 0.1 -0.1 0.2 0.1 -0.2
Major Depression (MDD) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Reaction Time 0.1 0.2 0.4 0.4 0.6 -0.2 -0.0 0.0 0.2 0.5 -0.7
Verbal and Numeric Reasoning (VNR) 4.5 10.7 16.4 -4.0 1.1 -1.0 3.2 -3.1 -4.0 -4.1 3.8
Breast Cancer 0.1 0.2 0.5 0.3 -0.5 0.7 -0.5 0.2 0.5 0.5 -0.2
Ovarian Cancer 0.2 0.3 1.6 -0.4 -1.3 -0.2 0.3 -0.3 -0.4 -0.4 0.5
Prostate Cancer 2.4 3.4 4.9 -1.8 1.7 -0.9 2.2 -2.2 -1.8 -2.0 1.9
Age at First Birth 0.1 0.1 0.4 0.1 0.6 -0.4 -0.1 0.0 0.0 0.1 -0.0
Bipolar Disorder (2011) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Body Mass Index (BMI) (2010) 0.1 0.1 0.4 -0.5 0.0 0.0 0.0 0.0 -0.6 0.0 0.0
Coronary Artery Disease (CAD) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0
Crohns Disease (2012) 0.6 1.0 2.1 -1.2 1.4 -1.2 1.2 -1.3 0.0 0.0 0.0
Mean Putamen Volume 0.7 0.8 1.1 -0.7 -0.6 0.9 1.0 -1.0 -0.9 -0.9 0.9
Fasting Glucose 3.3 4.0 6.1 -2.0 -1.2 -0.3 2.2 -2.3 -2.1 -2.3 2.5
HbA1C 0.1 0.2 0.4 0.5 0.7 0.0 -0.5 0.4 0.3 0.3 -0.1
HDL Cholesterol 0.4 0.6 1.0 0.9 -1.0 0.8 -1.0 0.9 1.0 0.0 0.0
LDL Cholesterol 3.0 4.7 24.9 1.1 5.0 2.7 -1.2 1.2 1.2 0.0 0.0
Lupus 0.3 0.5 2.5 -0.2 1.6 -0.3 0.1 -0.1 -0.1 -0.7 0.8
Neuroticism (2016) 0.3 0.5 2.3 -0.7 0.3 1.5 0.1 -0.0 -0.3 -0.7 0.6
Primary Biliary Cirrhosis 0.0 0.0 0.0 0.0 -0.2 0.0 0.0 0.0 0.0 0.0 0.0
Rheumatoid Arthritis 0.2 0.2 1.8 -0.2 -0.4 -1.3 0.0 -0.0 -0.2 0.0 0.0
Schizophrenia (2014) 0.2 0.5 1.3 -0.6 -1.2 0.1 0.5 -0.5 -0.6 -0.7 0.7
Triglycerides 0.1 0.1 0.3 -0.1 -0.4 -0.0 0.6 -0.5 -0.2 0.0 0.0
Type 2 Diabetes (T2D) (2012) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Ulcerative Colitis 0.6 0.8 4.8 0.5 2.2 0.8 -0.5 0.4 0.7 0.0 0.0
Blood Eosinophil Count 2.8 21.6 25.4 4.9 3.2 4.6 -4.7 4.7 5.0 5.0 -4.9
Blood Platelet Count 10.8 125.6 349.7 9.2 18.7 11.4 -9.5 9.6 9.0 9.4 -9.4
Blood Red Count 2.0 19.0 22.2 -4.4 -4.7 -4.7 4.1 -4.1 -4.4 -4.3 4.2
Blood White Count 1.3 9.8 13.1 3.6 1.6 2.0 -3.3 3.2 3.6 3.5 -3.5
Heel T-Score 0.0 0.2 0.9 -0.4 1.0 -0.6 0.3 -0.2 -0.4 -0.2 0.0
BMI 0.8 4.7 7.0 2.6 1.4 0.2 -2.5 2.5 2.7 2.4 -2.1
Height 2.6 49.8 104.0 -5.8 -10.2 -7.8 6.0 -6.1 -5.7 -6.7 7.0
Waist Hip Ratio (WHR) 3.8 16.9 20.1 -4.4 -3.5 -3.4 4.2 -4.2 -4.4 -4.5 4.2
Systolic Blood Pressure 0.8 4.2 12.7 -2.1 -3.6 -0.5 1.8 -1.7 -2.1 -1.8 1.6
Smoking Status 0.5 1.1 1.7 -0.8 1.0 -1.0 1.3 -1.3 -1.1 -1.0 1.0
Allergy or Eczema 0.1 0.3 0.6 -0.7 -0.2 0.5 0.4 -0.4 -0.8 -0.5 0.5
Cardiovascular Disease 0.5 1.7 3.2 -1.8 -0.0 0.3 1.6 -1.5 -1.6 -1.5 1.1
Hypothyroidism (self reported) 0.0 0.1 0.2 0.1 0.1 0.4 0.2 -0.3 0.2 -0.2 0.3
Respiratory disease 0.0 0.1 0.2 0.4 -0.3 0.0 0.2 -0.2 0.5 0.3 -0.2
Type 2 Diabetes (T2D) (2018) 1.4 2.6 3.8 -1.5 -1.7 -0.4 1.9 -1.9 -1.6 -1.7 1.7
Lung FEV1/FVC ratio 0.1 0.5 2.9 0.5 0.4 1.7 -0.4 0.4 0.7 0.3 -0.4
Lung FVC 1.0 4.9 8.8 2.4 0.5 0.2 -2.3 2.3 2.4 2.9 -3.0
Neuroticism 0.0 0.1 0.2 -0.3 -0.3 -0.4 -0.1 0.2 -0.2 -0.3 0.2
Chronotype (morning person) 0.5 1.2 5.0 0.6 2.2 1.1 -1.0 0.9 0.7 0.7 -0.7
Hair Pigment 0.0 0.9 4.3 0.3 2.1 1.1 -0.6 0.6 0.4 0.4 -0.5
Tanning 0.2 2.0 13.9 0.1 -3.7 -1.4 0.2 -0.2 0.2 0.1 0.1
Hand grip strength (left) 0.4 1.0 3.8 -0.6 -2.0 -0.5 0.8 -0.9 -0.9 -0.7 0.8
Number of treatments/medications taken 1.6 2.9 9.2 1.2 1.2 3.0 -1.4 1.4 1.4 1.5 -1.8
Average weekly spirits intake 1.8 2.2 2.9 1.5 -0.3 1.6 -1.5 1.4 1.7 1.7 -1.7
Sensitivity / hurt feelings 0.1 0.1 0.8 0.0 0.2 -0.9 0.2 -0.1 -0.1 0.0 0.0
Frequency of depressed mood in last 2 weeks 0.1 0.2 0.8 0.4 0.9 -0.2 -0.2 0.2 0.5 0.4 -0.4
Hearing difficulty/problems: Yes 4.2 6.4 9.7 -2.9 -0.6 -1.2 2.7 -2.6 -2.9 -3.1 3.1
Relative age of first facial hair 2.7 5.5 11.7 -2.3 -1.5 -3.4 2.1 -2.0 -2.0 -2.7 2.4
Other serious medical condition/disability diagnosed by doctor 5.0 6.5 10.2 3.0 -0.1 0.7 -2.7 2.6 3.2 3.1 -3.1
Ever used hormone-replacement therapy (HRT) 3.8 4.9 6.5 2.4 1.4 2.3 -2.3 2.2 2.5 2.2 -2.1
Ever had hysterectomy (womb removed) 4.1 4.6 6.7 -2.4 -1.0 -1.6 2.1 -2.1 -2.4 -2.6 2.5
Systolic blood pressure, automated reading 0.2 0.5 2.7 -0.7 -1.6 -0.4 0.4 -0.3 -0.7 -0.4 0.4
Eye problems/disorders: Diabetes related eye disease 0.3 0.4 1.6 -0.1 1.3 1.1 -0.0 0.0 -0.0 -0.2 0.2
Angina 0.9 1.1 4.2 0.9 -0.0 2.0 -0.8 0.8 1.1 0.8 -1.1
Medication for hormone replacement therapy 3.4 3.8 5.2 2.1 0.6 1.8 -2.0 2.0 2.3 2.3 -2.1
Vitamin and mineral supplements 2.1 2.8 3.8 1.8 1.4 -0.0 -1.8 1.8 1.9 2.0 -1.9
Supplements: Zinc 1.1 1.2 1.9 -1.3 0.3 -0.8 1.0 -1.0 -1.3 -1.4 1.1
Medication: Co-codamol 0.5 0.6 1.0 0.4 0.8 -0.6 -1.0 1.0 0.7 0.7 -0.7
Medication: Metformin 0.6 0.8 2.8 -0.6 -1.7 0.1 0.9 -0.9 -0.6 -0.8 0.8
Diabetes (father) 0.3 0.4 1.9 -0.6 -1.4 -0.1 0.4 -0.4 -0.5 -0.6 0.4
Diabetes (mother) 1.1 1.4 1.9 1.3 -1.1 0.7 -1.3 1.3 1.0 1.2 -1.4
Severe depression (siblings) 0.6 0.7 2.7 -0.9 1.6 -0.3 0.6 -0.6 -0.7 -0.7 0.7
Pack years adult smoking proportion 0.5 0.8 4.0 -0.7 -0.1 -2.0 0.1 -0.1 -0.6 -0.8 0.7
Impedance of leg (right) 1.1 5.1 7.0 -2.6 -1.1 -1.0 2.5 -2.5 -2.5 -2.6 2.5
Leg fat-free mass (left) 0.3 1.7 7.2 -0.3 -2.7 -2.3 -0.1 0.0 -0.1 -0.5 0.7
Trunk fat percentage 0.3 1.1 4.7 0.5 2.2 -1.0 -0.9 0.9 0.7 0.3 -0.2
Hand grip strength (right) 1.8 4.8 6.4 -2.2 -1.1 -2.4 2.1 -2.2 -2.3 -2.4 2.5
Townsend deprivation index at recruitment 0.5 0.6 0.8 0.7 0.2 0.8 -0.9 0.9 0.8 0.9 -0.9
Current tobacco smoking 1.1 1.8 3.8 -1.1 0.7 -1.9 1.6 -1.6 -1.3 -1.2 1.1
Average weekly fortified wine intake 4.0 4.7 6.1 -2.0 -2.4 -2.5 1.9 -2.0 -1.9 -2.2 2.3
Maternal smoking around birth 1.0 1.4 4.5 -0.9 -1.4 -2.1 0.8 -0.7 -0.8 -1.1 1.0
Fed-up feelings 0.4 0.7 1.4 0.6 -1.2 -0.9 -0.8 0.9 0.8 0.8 -0.8
Frequency of unenthusiasm / disinterest in last 2 weeks 0.2 0.2 0.3 0.4 0.5 -0.4 -0.4 0.4 0.5 0.5 -0.5
Relative age voice broke 2.5 3.8 7.3 -1.7 -1.6 -2.7 2.0 -2.0 -1.5 -2.0 1.9
Taking other prescription medications 1.6 2.5 3.4 1.7 0.7 1.7 -1.6 1.6 1.8 1.6 -1.5
Age when periods started (menarche) 1.2 2.8 3.4 -1.8 -1.8 -1.1 1.6 -1.6 -1.8 -1.9 1.6
Bilateral oophorectomy (both ovaries removed) 0.0 0.0 0.1 0.1 -0.0 -0.3 -0.1 0.1 0.3 -0.0 -0.0
Heel bone mineral density (BMD) T-score, automated (left) 0.4 1.0 7.2 -0.3 0.0 -2.7 0.5 -0.5 -0.3 -0.1 0.0
Tinnitus: Yes, but not now, but have in the past 0.4 0.4 1.9 -0.6 -1.4 0.1 0.1 -0.0 -0.3 -0.7 0.7
Qualifications: CSEs or equivalent 0.4 0.5 1.0 0.8 -1.0 -0.1 -0.5 0.5 0.8 0.8 -0.9
Serious illness, injury or assault to yourself 1.7 2.1 5.9 1.3 2.4 1.7 -1.0 1.0 1.3 1.1 -1.2
High blood pressure 0.4 1.0 2.1 -1.4 -0.1 0.2 1.1 -1.0 -1.3 -1.2 0.8
Hayfever, allergic rhinitis or eczema 0.3 0.6 1.0 -1.0 0.2 0.5 0.7 -0.7 -1.0 -0.9 0.9
Multivitamins +/- minerals 1.8 2.3 3.6 -1.8 -0.9 -0.1 1.6 -1.5 -1.9 -1.8 1.7
Stomach or abdominal pain in last month 1.0 1.2 9.0 0.3 -3.0 -0.3 -0.1 0.2 0.2 0.4 -0.4
Supplements: Glucosamine 1.0 1.3 2.1 -1.3 1.1 0.5 0.8 -0.8 -1.4 -1.4 1.4
Diverticular disease/diverticulitis (self-reported) 0.2 0.2 0.5 0.2 -0.7 0.7 -0.5 0.4 0.4 0.2 -0.2
Medication: Atenolol 0.1 0.1 0.3 -0.5 -0.3 -0.3 -0.1 0.0 -0.3 -0.5 0.3
Medication: Levothyroxine sodium 0.1 0.1 0.3 0.2 -0.5 0.4 0.3 -0.4 0.0 -0.2 0.4
Sitting height 1.7 11.7 46.8 -2.4 -6.8 -2.7 2.5 -2.5 -2.2 -2.8 3.0
Chronic bronchitis/emphysema (father) 1.1 1.2 2.0 1.3 -0.1 0.6 -1.1 1.1 1.4 1.3 -1.3
High blood pressure (mother) 5.0 7.0 8.5 2.9 0.7 2.8 -2.7 2.8 2.7 2.8 -2.8
Body mass index (BMI) 1.0 4.2 5.3 2.2 2.2 -0.6 -2.2 2.3 2.3 2.1 -2.0
Impedance of leg (left) 1.2 5.9 7.7 -2.8 -1.4 -1.1 2.7 -2.7 -2.7 -2.7 2.7
Leg predicted mass (left) 0.3 1.7 7.6 -0.2 -2.8 -2.4 -0.1 0.1 -0.1 -0.5 0.6
Trunk fat mass 0.2 0.7 3.6 0.4 0.5 -1.9 -0.8 0.8 0.6 0.1 0.1
Waist circumference 0.2 0.7 4.0 -0.3 0.8 -2.0 -0.0 -0.0 -0.2 -0.5 0.6
Number of incorrect matches in round 2.5 4.2 5.8 2.1 0.3 1.9 -2.2 2.2 2.4 2.3 -2.3
Past tobacco smoking 0.1 0.2 1.1 -0.3 -1.1 -0.6 -0.1 0.1 -0.1 -0.1 -0.0
Alcohol usually taken with meals 0.5 0.8 3.2 0.2 1.2 1.8 -0.8 0.9 0.2 0.2 -0.2
Nervous feelings 1.2 2.3 3.4 -1.8 0.6 -1.2 1.5 -1.5 -1.7 -1.8 1.7
Frequency of tenseness / restlessness in last 2 weeks 0.7 1.1 2.1 1.1 1.0 1.1 -0.8 0.9 0.9 1.2 -1.4
Hearing difficulty/problems with background noise 2.3 3.7 5.8 -1.9 -0.0 0.1 2.3 -2.3 -2.0 -2.4 2.4
Hair/balding pattern: Pattern 2 0.2 0.3 0.8 -0.4 -0.9 0.2 0.6 -0.6 -0.3 -0.5 0.5
Had menopause 1.6 2.0 2.7 1.6 1.6 0.7 -1.2 1.2 1.6 1.7 -1.6
Had other major operations 0.1 0.1 0.4 0.3 -0.6 -0.2 0.0 -0.1 0.4 0.2 -0.1
Forced vital capacity (FVC) 0.4 1.6 6.9 -0.7 -2.6 -1.6 0.7 -0.8 -0.7 -0.7 0.9
Heel bone mineral density (BMD) T-score, automated (right) 1.5 3.5 13.7 -1.4 -0.9 -3.7 1.8 -1.8 -1.3 -1.2 1.3
Ever unenthusiastic/disinterested for a whole week 0.6 0.7 4.0 0.2 2.0 0.4 -0.5 0.6 0.4 0.5 -0.6
Qualifications: None of the above 0.5 1.0 1.1 1.0 1.0 -0.8 -1.0 1.0 0.9 1.1 -1.0
Financial difficulties in last 2 years 3.1 4.2 5.6 2.1 -0.9 1.8 -2.2 2.2 2.2 2.2 -2.4
Mouth/teeth dental problems 0.7 1.1 3.5 0.9 -1.9 1.5 -0.7 0.6 0.7 0.7 -0.5
Heart attack 0.2 0.3 0.7 0.4 -0.2 0.9 -0.4 0.4 0.7 0.5 -0.7
Allergy 0.0 0.1 0.2 0.3 0.1 0.0 -0.4 0.4 0.3 0.2 -0.3
Pain all over the body in last month 1.1 1.2 1.6 1.0 -1.2 0.8 -1.1 1.0 1.3 1.1 -1.2
Diabetes (self-reported) 1.0 1.5 2.1 -1.1 -1.4 -1.0 1.4 -1.4 -1.1 -1.2 1.2
Hayfever/allergic rhinitis (self-reported) 0.5 0.6 0.8 0.6 -0.9 0.9 -0.8 0.8 0.8 0.8 -0.8
Medication: Ramipril 0.4 0.5 2.5 -0.5 0.6 1.6 0.0 0.2 -0.3 -0.6 0.4
Medication: Simvastatin 0.8 1.2 8.0 -0.3 2.8 1.0 0.5 -0.5 -0.2 -0.4 0.3
Fluid intelligence score 3.4 7.1 11.4 -3.4 0.7 -0.6 2.6 -2.5 -3.3 -3.3 3.1
Illnesses of siblings 0.4 0.5 1.4 -0.3 -0.1 -0.4 1.1 -1.2 -0.5 -0.7 0.8
Neuroticism score 0.3 0.5 1.4 -0.8 -0.5 -1.2 0.5 -0.4 -0.8 -0.7 0.6
Weight 0.3 1.3 6.7 0.0 -1.7 -2.6 -0.2 0.2 0.2 -0.3 0.5
Impedance of arm (right) 0.6 2.7 9.8 -1.4 3.1 1.7 0.9 -0.8 -1.3 -1.4 1.4
Arm fat percentage (right) 1.3 5.2 17.3 2.0 4.2 -0.2 -2.3 2.3 2.1 1.8 -1.6
Trunk fat-free mass 1.4 8.1 34.1 -1.4 -5.8 -4.0 1.4 -1.5 -1.4 -1.7 1.9
Hip circumference 0.3 1.3 4.4 0.9 2.1 -0.8 -1.1 1.1 1.1 0.6 -0.3
Time employed in main current job 0.5 0.6 1.6 0.7 -0.4 1.3 -0.7 0.8 0.6 0.8 -0.6
Alcohol intake versus 10 years previously 0.6 0.9 2.0 0.9 0.0 1.4 -0.7 0.7 0.9 1.0 -1.2
Father’s age at death 0.4 0.5 0.9 0.9 0.8 0.1 -0.7 0.6 0.7 0.9 -0.8
Worrier / anxious feelings 0.2 0.4 3.0 0.0 -1.7 -0.6 0.0 0.1 0.1 0.2 -0.2
Frequency of tiredness / lethargy in last 2 weeks 0.1 0.1 0.3 -0.5 0.4 -0.2 0.4 -0.3 -0.3 -0.3 0.2
Falls in the last year 0.7 1.0 7.1 -0.1 2.7 -0.6 -0.4 0.5 0.2 -0.0 -0.1
Hair/balding pattern: Pattern 3 0.1 0.1 0.2 0.3 0.1 -0.4 -0.4 0.4 0.1 0.3 -0.4
Number of live births 1.9 2.7 4.7 1.5 -2.2 -1.8 -1.4 1.4 1.3 1.7 -1.8
Forced expiratory volume in 1-second (FEV1) 0.1 0.4 3.2 -0.2 -1.8 -0.2 0.1 -0.0 -0.1 -0.2 0.2
Pulse rate 0.6 0.9 1.5 1.1 1.2 0.5 -0.9 0.8 1.2 1.0 -0.9
Happiness 0.1 0.1 0.2 0.2 -0.2 0.3 -0.3 0.4 0.3 0.5 -0.5
Noisy workplace 0.7 0.9 3.3 0.8 1.8 1.2 -0.5 0.6 0.5 0.6 -0.5
Qualifications: A levels/AS levels or equivalent 3.2 7.1 10.6 -3.3 -0.3 -0.5 2.9 -2.9 -3.2 -3.1 3.0
Serious illness, injury or assault of a close relative in last 2 years 0.7 0.8 1.9 -0.9 1.4 0.2 0.9 -0.8 -0.9 -0.8 1.1
Mouth/teeth dental problems: Dentures 0.1 0.1 0.3 0.2 0.5 -0.5 -0.2 0.2 0.2 0.4 -0.5
Asthma 0.3 0.6 1.1 1.0 -0.8 0.6 -0.4 0.3 1.1 0.9 -0.7
Medication: Ibuprofen (e.g. Nurofen) 0.5 0.6 3.9 0.0 -2.0 -0.8 -0.0 0.0 -0.1 0.1 -0.3
Medication: Cholesterol lowering 3.7 5.7 19.4 1.7 4.4 3.2 -1.3 1.4 1.8 1.7 -1.8
Depression (self-reported) 0.2 0.3 0.4 -0.5 0.6 0.6 0.4 -0.4 -0.7 -0.5 0.5
Medication: Lansoprazole 0.6 0.7 1.6 -0.8 1.2 -0.1 0.9 -1.0 -0.6 -0.8 0.7
Prospective memory result 0.9 1.1 1.6 1.1 0.9 0.2 -1.0 0.9 1.2 1.3 -1.3
Lung cancer (father) 0.1 0.1 0.4 -0.0 0.4 0.6 0.1 -0.1 -0.1 0.0 -0.2
Illnesses of mother 1.5 1.9 3.0 -1.4 -0.4 -1.3 1.7 -1.7 -1.0 -1.4 1.5
Forced expiratory volume in 1-second (FEV1), Best measure 0.3 0.8 5.0 0.1 -2.2 -1.1 -0.4 0.4 0.2 0.1 -0.2
Pulse wave Arterial Stiffness index 0.8 0.9 3.0 0.9 1.7 -0.2 -0.8 0.8 0.8 0.9 -0.9
Impedance of arm (left) 0.5 2.5 8.6 -1.3 2.9 1.8 0.8 -0.7 -1.2 -1.4 1.4
Arm fat mass (right) 0.4 1.8 2.9 1.3 1.7 -1.4 -1.5 1.5 1.4 1.1 -0.9
Trunk predicted mass 1.3 7.4 32.1 -1.3 -5.7 -3.8 1.3 -1.3 -1.2 -1.6 1.8
Standing height 2.8 28.2 75.9 -4.4 -8.7 -4.8 4.1 -4.2 -4.3 -5.0 5.3
Length of working week for main job 1.0 1.1 2.6 1.0 -0.0 1.6 -1.0 1.1 1.0 1.0 -1.0
Exposure to tobacco smoke at home 3.6 4.0 6.1 1.9 0.3 1.2 -2.5 2.5 2.1 2.3 -2.2
Breastfed as a baby 1.3 1.6 4.5 -0.9 2.1 -0.8 1.3 -1.3 -1.0 -1.0 1.3
Tense / ‘highly strung’ 1.6 2.6 7.5 -1.4 -0.4 -2.7 1.6 -1.5 -1.4 -1.5 1.4
Seen doctor (GP) for nerves, anxiety, tension or depression 1.3 2.0 5.2 -1.2 2.3 0.7 1.5 -1.5 -1.3 -1.2 1.1
Hair/balding pattern: Pattern 4 2.2 5.4 7.5 2.6 -0.0 2.1 -2.7 2.7 2.6 2.4 -2.3
Birth weight of first child 1.5 2.6 5.0 -1.6 -0.4 -2.2 1.4 -1.5 -1.8 -1.8 1.8
Peak expiratory flow (PEF) 0.1 0.2 0.5 -0.4 -0.7 -0.3 0.4 -0.4 -0.1 -0.4 0.5
Pulse wave reflection index 0.3 0.3 1.5 -0.4 1.2 0.0 0.4 -0.4 -0.5 -0.5 0.4
Ever highly irritable/argumentative for 2 days 0.1 0.1 0.3 0.0 0.4 -0.6 0.0 0.1 0.1 0.1 -0.3
Loud music exposure frequency 0.2 0.2 0.9 -0.3 -0.3 -1.0 -0.2 0.1 -0.3 -0.2 0.2
Qualifications: O levels/GCSEs or equivalent 1.2 1.9 3.1 -1.8 -1.2 -0.6 1.2 -1.2 -1.7 -1.6 1.4
Mouth/teeth dental problems: Bleeding gums 0.6 0.7 5.4 -0.3 2.3 -0.4 -0.0 0.1 0.0 -0.4 0.3
Blood clot in the leg (DVT) 1.5 1.9 3.2 1.3 -0.7 0.4 -1.7 1.8 1.5 1.5 -1.5
Medication: Paracetamol 0.1 0.1 0.6 -0.1 0.6 -0.7 -0.0 -0.0 0.1 -0.2 0.1
Headache pain in last month 0.0 0.0 0.1 0.0 0.3 -0.3 0.2 -0.2 -0.2 -0.2 0.3
Medication for cholesterol, blood pressure or diabetes 0.5 0.9 4.9 0.1 -1.4 -2.2 -0.0 -0.1 0.0 -0.1 0.3
Glaucoma (self-reported) 0.3 0.3 1.8 0.1 1.3 0.8 0.1 -0.0 0.3 0.3 -0.5
Gout (self-reported) 0.3 0.4 0.7 -0.7 -0.4 -0.7 0.8 -0.9 -0.6 -0.5 0.6
Hypothyroidism/myxoedema (self-reported) 0.1 0.3 0.8 0.5 -0.9 0.8 -0.2 0.1 0.5 0.3 -0.0
Medication: Amlodipine 0.8 1.1 1.8 -1.3 -0.5 -0.0 1.3 -1.3 -1.1 -1.2 1.0
Medication: Ventolin 100micrograms inhaler 0.4 0.6 3.1 -0.1 -1.8 0.9 0.5 -0.6 0.0 -0.1 0.3
Birth weight 2.0 4.3 6.2 -2.0 2.5 -0.4 2.4 -2.4 -1.9 -2.1 2.2
Chronic bronchitis/emphysema (mother) 0.1 0.2 0.4 -0.5 -0.1 -0.4 0.2 -0.2 -0.4 -0.5 0.7
High blood pressure (siblings) 0.6 0.9 1.7 0.8 -0.4 0.9 -1.3 1.3 0.9 0.9 -0.9
Forced vital capacity (FVC), Best measure 0.5 1.7 8.6 -0.2 -2.9 -2.2 -0.0 0.0 -0.2 -0.2 0.2
Body fat percentage 0.4 1.7 7.0 0.9 2.6 -1.0 -1.2 1.2 1.1 0.7 -0.6
Leg fat percentage (right) 0.5 1.7 6.0 1.0 2.5 -1.3 -1.1 1.1 1.1 0.9 -0.7
Arm fat-free mass (right) 1.4 7.3 31.7 -1.3 -5.6 -3.9 1.4 -1.4 -1.2 -1.5 1.7
Exposure to tobacco smoke outside home 0.2 0.3 1.6 0.0 -1.3 -0.7 -0.3 0.4 0.3 0.2 -0.2
Comparative body size at age 10 0.1 0.2 0.3 -0.1 0.5 -0.3 -0.6 0.6 0.1 -0.2 0.4
Number of full brothers 0.2 0.2 1.5 0.2 -1.2 -0.2 0.0 -0.0 0.3 0.1 -0.4
Worry too long after embarrassment 2.1 3.6 4.8 -2.2 -0.9 -1.8 2.2 -2.1 -2.0 -1.9 1.7
Seen a psychiatrist for nerves, anxiety, tension or depression 0.6 0.7 2.0 -0.7 1.4 0.6 0.9 -0.8 -0.7 -0.8 0.7
Wheeze or whistling in the chest in last year 0.0 0.1 0.1 0.0 -0.4 0.1 0.2 -0.3 0.3 -0.1 0.3
Number of children fathered 0.6 0.7 2.1 0.8 1.4 0.9 -0.5 0.5 0.7 0.7 -0.6
Reason for reducing amount of alcohol drunk: Health precaution 0.9 1.0 1.4 -0.8 -1.0 -0.9 1.1 -1.1 -0.8 -1.1 1.2
Age at first live birth 0.8 1.4 3.1 -1.2 1.7 0.8 1.1 -1.1 -1.4 -1.1 0.9
Pulse wave peak to peak time 1.2 1.4 5.0 -1.1 -2.2 -0.0 0.9 -0.9 -1.0 -1.1 1.1
Health satisfaction 0.0 0.1 0.1 -0.3 -0.3 0.1 0.2 -0.1 -0.4 -0.2 0.0
Shortness of breath walking on level ground 1.1 1.3 1.8 -1.1 1.3 -0.8 1.1 -1.1 -1.2 -1.3 1.2
Qualifications: College or University degree 1.0 3.0 4.3 -2.0 -2.1 -0.1 1.6 -1.5 -1.9 -1.9 1.9
Eye problems/disorders: None of the above 1.5 1.8 2.3 1.3 -1.5 1.3 -1.2 1.3 1.2 1.5 -1.3
Mouth/teeth dental problems: Loose teeth 1.2 1.4 2.5 1.5 0.0 -1.1 -1.1 1.1 1.6 1.4 -1.1
Emphysema/chronic bronchitis 2.4 2.7 4.3 -1.5 -0.2 -2.1 1.8 -1.9 -1.6 -1.7 1.6
Medication for pain relief, constipation, heartburn 0.7 1.2 2.8 -0.8 0.0 -1.7 1.2 -1.2 -0.9 -1.0 1.3
Neck or shoulder pain in last month 0.2 0.3 0.7 0.3 -0.8 -0.0 -0.4 0.5 0.5 0.6 -0.8
Medication: Blood pressure 0.5 0.9 4.0 -0.6 -2.0 1.3 0.4 -0.3 -0.5 -0.5 0.4
Angina (self-reported) 1.0 1.3 4.2 1.0 -0.3 2.0 -0.9 1.0 1.2 0.9 -1.2
Migraine (self-reported) 0.3 0.3 0.4 0.6 0.6 0.4 -0.6 0.7 0.6 0.6 -0.5
Medication: Ibuprofen 0.7 0.8 1.9 0.7 -1.4 -0.3 -0.8 0.8 0.6 0.9 -1.2
Medication: Allopurinol 0.8 1.1 2.2 -0.7 -1.2 -1.5 1.2 -1.3 -0.8 -0.7 0.7
Medication: Omeprazole 1.2 1.5 2.2 1.1 0.3 1.5 -1.5 1.5 1.2 1.1 -1.2
Medication: Seretide 50 evohaler 0.3 0.3 1.7 0.0 1.3 0.9 0.1 -0.1 -0.0 -0.2 0.1
Mean time to correctly identify matches 0.1 0.2 0.8 0.3 0.9 -0.3 0.1 -0.1 0.1 0.4 -0.5
Heart disease (mother) 0.1 0.1 0.8 -0.2 -0.1 0.9 -0.2 0.3 -0.3 0.0 -0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.0 1.2 3.7 -0.9 1.9 0.7 1.0 -1.1 -0.8 -0.8 0.8
Whole body fat mass 0.2 0.9 4.0 0.7 0.5 -2.0 -0.9 0.9 0.9 0.4 -0.2
Leg fat mass (right) 0.3 1.0 4.3 0.6 0.6 -2.1 -0.9 0.9 0.8 0.5 -0.3
Arm predicted mass (right) 1.4 7.2 31.0 -1.1 -5.6 -4.0 1.3 -1.3 -1.1 -1.4 1.7
Pulse rate, automated reading 0.4 1.2 6.2 -0.4 -2.5 -1.4 0.7 -0.8 -0.3 -0.4 0.6
Alcohol intake frequency. 0.2 0.4 2.4 0.0 1.6 0.3 -0.2 0.3 -0.1 0.2 -0.3
Comparative height size at age 10 2.0 10.8 38.2 -2.7 -6.2 -1.7 2.3 -2.4 -2.6 -3.0 3.3
Number of full sisters 0.2 0.2 0.8 -0.3 0.0 -0.9 0.4 -0.5 -0.3 -0.3 0.4
Suffer from ‘nerves’ 0.2 0.4 2.4 0.2 1.6 0.6 -0.2 0.2 0.3 0.1 -0.1
Overall health rating 0.4 0.8 1.6 0.8 -0.0 -1.0 -0.6 0.7 1.0 1.1 -1.3
Chest pain or discomfort 0.9 1.4 1.9 -0.9 -1.2 -1.4 1.3 -1.3 -1.0 -1.1 1.0
Had major operations 2.2 2.6 4.1 1.7 0.4 0.5 -1.9 2.0 1.6 1.8 -1.9
Age at last live birth 0.7 1.0 2.0 -1.3 0.5 0.1 1.1 -1.0 -1.4 -1.1 0.8
Family relationship satisfaction 0.1 0.1 0.3 -0.0 -0.4 -0.1 0.5 -0.4 -0.1 -0.2 0.4
Leg pain on walking 0.7 0.9 4.2 0.4 2.1 0.7 -0.9 0.9 0.5 0.5 -0.7
Qualifications: NVQ or HND or HNC or equivalent 0.4 0.5 1.0 0.5 0.4 -0.3 -0.9 1.0 0.6 0.8 -0.7
Commuting to job workplace: Car/motor vehicle 0.9 1.1 6.6 0.4 2.6 0.3 -0.5 0.6 0.4 0.6 -0.7
Illness, injury, bereavement, stress in last 2 years 0.6 0.8 4.9 -0.6 -2.2 -0.3 0.4 -0.4 -0.5 -0.4 0.4
Medication: Aspirin 0.8 1.0 4.9 0.2 0.9 2.2 -0.6 0.7 0.7 0.5 -0.8
Supplements: Vitamin C 3.9 4.6 6.2 -2.2 -1.7 -0.8 2.4 -2.5 -2.3 -2.4 2.4
Knee pain experienced in last month 1.0 1.5 8.0 -0.2 -1.6 -2.8 0.7 -0.8 -0.4 -0.3 0.2
Hypertension (Self-reported) 0.4 1.2 2.3 -1.5 -0.4 0.1 1.2 -1.1 -1.4 -1.2 0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.4 0.5 1.0 0.5 0.5 0.2 -1.0 1.0 0.6 0.7 -0.8
Illnesses of father: Heart disease 0.2 0.2 1.3 -0.2 1.2 -0.1 0.3 -0.2 -0.1 -0.4 0.5
Illnesses of siblings: Diabetes 0.3 0.4 0.8 0.8 -0.3 0.8 -0.3 0.3 0.9 0.7 -0.5
Smoking status: Previous 0.3 0.4 1.4 0.6 0.9 1.2 -0.2 0.3 0.5 0.5 -0.4
Forced expiratory volume in 1-second (FEV1), predicted 0.9 1.9 9.1 -0.7 -3.0 -0.6 0.8 -0.9 -0.7 -1.2 1.3
Whole body fat-free mass 0.9 5.4 24.4 -0.9 -4.9 -3.5 0.8 -0.9 -0.9 -1.2 1.4
Leg fat-free mass (right) 0.4 1.9 8.7 -0.4 -3.0 -2.4 0.1 -0.1 -0.3 -0.6 0.8
Arm fat percentage (left) 1.2 5.0 16.7 1.9 4.1 -0.1 -2.2 2.3 2.0 1.7 -1.5
Average weekly red wine intake 3.0 4.4 5.7 -2.3 -1.0 -2.0 2.0 -2.1 -2.4 -2.4 2.4
Handedness (chirality/laterality): Left-handed 0.5 0.6 1.8 0.7 -0.3 1.4 -0.7 0.7 0.5 0.7 -0.6
Mood swings 0.1 0.2 0.6 0.5 -0.3 -0.8 -0.2 0.2 0.6 0.5 -0.6
Loneliness, isolation 0.1 0.1 0.4 -0.3 0.1 -0.2 0.6 -0.5 -0.4 -0.3 0.4
Long-standing illness, disability or infirmity 0.6 0.9 3.6 0.8 1.9 1.2 -0.3 0.4 0.8 0.7 -0.8
Ever had bowel cancer screening 0.6 0.7 2.2 1.0 0.3 1.5 -0.3 0.3 0.8 0.8 -0.9
Diabetes diagnosed by doctor 1.0 1.7 2.3 -1.2 -1.5 -0.8 1.5 -1.5 -1.2 -1.3 1.3
Ever had stillbirth, spontaneous miscarriage or termination 2.5 2.6 4.7 -1.5 -1.0 -1.5 2.1 -2.2 -1.4 -1.4 1.6
Friendships satisfaction 0.5 0.7 2.7 -0.6 -1.6 -0.3 0.5 -0.5 -0.8 -0.6 0.7
Qualifications: nursing, teaching 0.2 0.4 1.3 -0.5 0.3 1.2 0.5 -0.5 -0.5 -0.5 0.5
Commuting to job workplace: Walk 3.3 3.6 5.3 -2.2 -1.0 -0.9 1.9 -1.9 -2.1 -2.3 2.2
Eye problems/disorders: Cataract 0.5 0.6 3.1 -0.2 1.1 -1.8 0.2 -0.3 -0.2 -0.5 0.4
Mouth/teeth dental problems: Mouth ulcers 5.4 8.7 12.2 -3.5 0.3 -1.6 3.3 -3.2 -3.2 -3.5 3.4
Medication for cholesterol 0.5 0.7 2.1 -0.7 -1.4 -0.5 0.6 -0.7 -0.8 -0.8 0.8
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.6 1.8 3.9 1.3 -0.6 2.0 -1.3 1.4 1.2 1.2 -1.4
Back pain experienced in last month 0.7 1.1 2.2 1.1 0.9 -1.0 -0.8 0.8 0.9 1.2 -1.5
Mineral and other dietary supplements 0.7 0.9 1.5 1.2 -1.0 -0.2 -0.6 0.6 1.2 1.2 -1.1
Breast cancer (self-reported) 1.0 1.2 2.1 -1.2 0.2 -0.5 1.1 -1.1 -1.2 -1.3 1.5
Asthma (self-reported) 0.2 0.4 0.7 0.8 -0.7 0.6 -0.1 0.1 0.8 0.7 -0.5
Osteoporosis (self-reported) 1.8 2.2 3.7 1.8 1.9 0.3 -1.4 1.3 1.6 1.5 -1.4
Osteoarthritis (self-reported) 0.3 0.4 2.1 -0.3 1.4 0.3 0.5 -0.5 -0.4 -0.5 0.5
Medication: Aspirin 1.6 2.0 7.5 0.8 1.1 2.7 -1.1 1.2 1.2 1.1 -1.3
Medication: Gliclazide 0.8 0.9 4.4 0.7 -0.2 2.1 -0.6 0.7 0.9 0.6 -0.5
Illnesses of father: None of the above (group 1) 0.5 0.7 1.7 -0.7 -0.7 -1.3 0.6 -0.7 -0.9 -0.6 0.6
Smoking status: Current 1.3 2.1 3.1 -1.3 0.8 -1.7 1.7 -1.8 -1.4 -1.4 1.3
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.2 0.5 0.7 0.5 0.6 0.4 -0.8 0.8 0.5 0.7 -0.9
Whole body water mass 0.9 5.1 23.3 -0.9 -4.8 -3.4 0.8 -0.8 -0.8 -1.2 1.4
Leg predicted mass (right) 0.3 1.8 8.6 -0.3 -2.9 -2.3 -0.0 -0.0 -0.2 -0.5 0.7
Arm fat mass (left) 0.6 2.5 3.3 1.6 1.7 -1.2 -1.8 1.8 1.7 1.4 -1.2
Number of self-reported non-cancer illnesses 0.3 0.5 1.2 0.6 0.7 0.7 -0.4 0.5 0.7 0.9 -1.1
Average weekly champagne plus white wine intake 0.7 0.9 3.6 0.7 -0.4 1.9 -0.7 0.7 0.8 0.8 -0.8
Miserableness 1.7 2.9 3.8 -1.9 -0.4 -1.4 1.8 -1.8 -2.0 -1.9 1.9
Guilty feelings 0.4 0.5 3.4 -0.1 -0.8 -1.8 0.2 -0.3 -0.2 -0.1 0.2
Wears glasses or contact lenses 0.3 0.3 0.7 -0.2 -0.7 -0.4 0.8 -0.9 -0.0 -0.5 0.6
Ever taken oral contraceptive pill 0.5 0.6 2.7 0.7 -1.6 0.3 -0.6 0.5 0.5 0.7 -0.5
Hearing aid user 0.9 1.0 5.7 0.0 1.4 2.4 -0.3 0.3 0.0 -0.1 0.1
Mother’s age at death 1.4 1.8 2.8 -1.4 -0.7 -1.7 1.1 -1.1 -1.4 -1.4 1.5
Financial situation satisfaction 0.4 0.5 2.1 0.4 -1.2 1.4 -0.3 0.3 0.4 0.3 -0.4
Tinnitus: Yes, now most or all of the time 1.1 1.3 1.6 1.1 1.1 1.2 -1.3 1.3 1.0 1.1 -1.0
Commuting to job workplace: Public transport 2.4 2.8 4.1 -1.9 -1.4 -1.4 1.4 -1.4 -1.8 -1.9 2.0
Eye problems/disorders: Glaucoma 0.5 0.6 2.5 -0.7 1.6 -0.2 0.8 -0.8 -0.4 -0.4 0.3
Medication: Blood pressure 0.1 0.2 1.1 -0.5 1.1 -0.0 0.0 0.0 -0.1 -0.2 0.1
Pain type(s) experienced in last month: Hip pain 0.3 0.4 2.1 -0.2 1.4 0.6 -0.4 0.5 -0.2 0.1 -0.4
Supplements: Fish oil (including cod liver oil) 0.3 0.4 0.8 -0.8 0.4 0.0 0.4 -0.4 -0.9 -0.8 0.6
High cholesterol (Self-reported) 1.1 2.0 14.4 -0.2 3.8 0.9 0.5 -0.3 -0.1 -0.2 -0.0
Medication: Bendroflumethiazide 0.3 0.4 2.6 0.1 -0.8 1.6 -0.3 0.3 0.3 0.1 -0.3
Medication: Paracetamol 0.5 0.8 1.1 1.0 1.1 0.5 -0.9 0.8 1.1 0.9 -1.0
Medication: Lisinopril 0.3 0.4 1.1 0.2 -0.9 -1.0 -0.5 0.5 0.5 0.3 -0.4
Medication: Atorvastatin 1.4 1.8 12.7 -0.1 3.6 1.2 0.3 -0.2 -0.1 0.0 -0.2
Illnesses of father: High blood pressure 0.3 0.3 1.4 0.5 0.3 1.2 -0.6 0.6 0.5 0.3 -0.1
Alcohol drinker status: Never 0.4 0.4 0.9 -0.9 0.2 0.0 0.6 -0.5 -0.8 -0.8 0.9
Ever smoked 0.2 0.3 1.0 0.6 1.0 0.3 -0.3 0.3 0.3 0.6 -0.5
Basal metabolic rate 0.7 4.0 16.4 -0.8 -4.0 -3.3 0.6 -0.6 -0.7 -1.0 1.2
Leg fat percentage (left) 0.4 1.5 4.5 0.9 2.1 -1.4 -1.1 1.1 1.1 0.8 -0.7
Arm fat-free mass (left) 1.1 5.4 24.2 -0.9 -4.9 -3.6 0.9 -1.0 -0.8 -1.1 1.3
Number of operations (self-reported) 0.3 0.5 1.3 0.9 -1.1 -0.4 -0.1 0.2 0.7 0.7 -0.7
Average weekly beer plus cider intake 0.9 1.3 4.6 1.4 0.0 -2.1 -0.5 0.4 1.1 1.1 -1.0
Irritability 0.9 1.4 2.2 -1.3 -0.4 -0.9 1.3 -1.1 -1.3 -1.5 1.4
Risk taking 0.2 0.3 1.0 0.6 1.0 0.4 -0.4 0.4 0.7 0.5 -0.4
Ever had prostate specific antigen (PSA) test 1.3 1.5 5.0 0.9 1.1 2.2 -1.1 1.1 1.0 0.9 -1.0
Fractured/broken bones in last 5 years 0.0 0.0 0.1 0.1 -0.3 -0.2 0.0 -0.1 0.0 0.1 -0.1
Age started oral contraceptive pill 1.8 2.3 3.0 -1.7 0.2 -1.4 1.5 -1.5 -1.7 -1.7 1.7
Diastolic blood pressure, automated reading 0.1 0.3 0.6 0.4 -0.5 -0.4 -0.6 0.6 0.3 0.8 -0.8
Ever depressed for a whole week 1.4 1.7 5.1 0.8 2.3 2.0 -0.8 0.9 0.9 0.9 -1.0
Unable to work because of sickness or disability 0.4 0.5 2.2 -0.5 0.7 -1.5 0.5 -0.5 -0.4 -0.3 0.2
Commuting to job workplace: Cycle 0.4 0.5 0.9 -0.9 0.1 0.2 0.6 -0.6 -0.8 -0.9 1.0
Myopia 0.2 0.2 0.7 -0.6 -0.8 -0.8 0.1 -0.1 -0.3 -0.4 0.4
Vascular/heart problems diagnosed by doctor 0.2 0.5 1.3 1.1 -0.1 -0.8 -0.6 0.5 0.8 0.9 -0.5
Cholesterol lowering medication 0.5 0.7 5.1 -0.2 2.3 0.5 0.3 -0.4 -0.0 -0.3 0.2
Medication: Omeprazole (e.g. Zanprol) 1.7 2.1 3.3 1.4 0.6 1.5 -1.8 1.8 1.4 1.3 -1.4
Pain experienced in last month 0.3 0.6 1.2 -0.8 0.1 0.8 0.7 -0.7 -0.6 -0.9 1.1
Supplements: Calcium 0.3 0.4 0.5 -0.6 -0.4 -0.4 0.7 -0.7 -0.6 -0.7 0.7
Basal cell carcinoma (self-reported) 0.0 0.1 0.2 0.0 -0.1 0.4 -0.2 0.2 0.3 -0.1 0.1
Heart attack/myocardial infarction (self-reported) 0.2 0.2 0.8 0.3 0.0 0.9 -0.2 0.3 0.6 0.5 -0.6
Deep venous thrombosis (DVT) (self-reported) 1.8 2.3 3.9 1.4 -0.3 0.8 -1.9 2.0 1.6 1.6 -1.6
Heart disease (siblings) 0.1 0.2 0.3 0.0 0.5 0.3 -0.5 0.5 0.2 0.2 -0.4
Alcohol drinker status: Previous 0.1 0.2 0.3 0.3 0.2 0.0 -0.5 0.5 0.3 0.5 -0.5
Pack years of smoking 0.7 1.1 4.7 -1.0 0.1 -2.2 0.4 -0.4 -0.9 -1.0 0.9
Impedance of whole body 0.7 3.7 5.5 -2.3 1.0 0.5 2.0 -1.9 -2.2 -2.4 2.3
Leg fat mass (left) 0.3 1.1 4.4 0.7 0.5 -2.1 -1.0 1.0 0.9 0.6 -0.4
Arm predicted mass (left) 1.1 5.6 23.4 -1.0 -4.8 -3.7 1.0 -1.0 -1.0 -1.3 1.4