TWAS hub - GPR116

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Brain Cortex	0.3120	0.1110	0.00670	0.004	NA	-0.007	NA	0.002	2.4e-01	NA	5.6e-01	NA	2.7e-01
2	TCGA	Breast Invasive Carcinoma	0.0391	0.0157	0.00031	0.030	0.023	0.018	NA	0.022	6.8e-07	1.1e-05	9.4e-05	NA	1.8e-05
3	TCGA	Brain Lower Grade Glioma	0.0700	0.0347	0.00830	0.010	0.012	0.006	NA	0.005	2.1e-02	1.5e-02	5.7e-02	NA	7.9e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Qualifications: NVQ or HND or HNC or equivalent	4.5	5.4	8.4	-1.9	-2.9	-2.1
Medication: Gliclazide	3.7	4.2	5.6	2.0	2.4	1.8
Chronic bronchitis/emphysema (mother)	3.4	4.0	8.2	-2.9	-1.9	-0.5
Heart disease (mother)	3.3	4.0	5.0	1.6	2.2	2.1
Neuroticism (2016)	3.1	4.4	9.2	-3.0	-1.8	1.0
Loud music exposure frequency	2.9	3.2	4.8	-0.3	-2.2	-2.2
Guilty feelings	2.9	4.4	8.5	-1.4	-1.6	-2.9
Diabetes diagnosed by doctor	2.8	4.6	9.0	3.0	2.1	-0.5
HbA1C	2.7	3.0	6.5	2.5	0.1	1.5
Angina	2.7	3.5	9.1	0.4	3.0	-1.1
Hayfever/allergic rhinitis (self-reported)	2.7	3.6	6.5	-1.5	1.4	2.5
Basal cell carcinoma (self-reported)	2.6	3.1	5.7	1.9	2.4	-0.2
Mean Putamen Volume	2.5	2.8	4.3	-1.6	1.2	2.1
Medication: Metformin	2.5	3.5	7.3	1.7	2.7	-0.4
Chronic bronchitis/emphysema (father)	2.5	2.9	4.5	-2.1	-0.1	-2.0
Alcohol usually taken with meals	2.5	4.0	10.5	3.2	0.7	1.0
Angina (self-reported)	2.5	3.3	9.1	0.3	3.0	-0.9
Medication: Atenolol	2.4	3.0	4.1	-1.2	2.0	1.9
Lung cancer (father)	2.3	2.7	7.8	-2.8	-0.6	-0.2
Emphysema/chronic bronchitis	2.3	2.6	7.2	0.5	0.6	-2.7
Hair/balding pattern: Pattern 2	2.2	2.8	5.1	-2.2	-1.0	-1.5
Heart attack	2.2	2.8	5.2	-0.1	1.8	2.3
Leg pain on walking	2.2	2.7	3.5	-1.8	-1.9	-1.2
Schizophrenia (2018)	2.1	4.3	9.6	0.0	-1.8	-3.1
Reaction Time	2.1	4.0	6.9	-1.5	1.8	2.6
Heart attack/myocardial infarction (self-reported)	2.1	2.7	4.7	0.0	1.8	2.2
Diabetes (mother)	2.0	2.5	2.7	1.6	1.6	-1.5
Eye problems/disorders: Cataract	2.0	2.3	6.6	2.6	0.3	0.3
Supplements: Fish oil (including cod liver oil)	2.0	2.6	6.8	-2.6	0.8	0.6
Worrier / anxious feelings	1.9	3.6	6.0	-2.4	0.9	2.0
Falls in the last year	1.9	2.5	4.9	0.3	-2.2	-1.6
Number of live births	1.9	2.6	6.8	-2.6	-0.4	-1.0
Eye problems/disorders: None of the above	1.9	2.1	3.2	-1.8	-1.8	0.4
Ever had prostate specific antigen (PSA) test	1.9	2.2	4.5	0.6	-1.3	-2.1
Birth weight of first child	1.8	3.2	6.0	2.4	0.7	1.8
Taking other prescription medications	1.7	2.5	6.5	1.0	2.5	-0.2
Tinnitus: Yes, but not now, but have in the past	1.7	1.8	3.4	1.8	1.3	0.6
Hair/balding pattern: Pattern 3	1.7	2.5	5.9	0.8	1.1	2.4
Mean time to correctly identify matches	1.7	3.3	3.9	-1.5	2.0	1.9
Average weekly red wine intake	1.7	2.5	7.5	2.7	-0.2	-0.2
Ever had bowel cancer screening	1.7	2.0	3.1	-1.8	-0.2	-1.7
Heart disease (siblings)	1.7	2.0	5.1	-2.3	1.0	-0.2
Waist Hip Ratio (WHR)	1.6	7.1	11.6	1.6	2.7	3.4
Pain all over the body in last month	1.6	1.7	4.6	-2.1	-0.2	0.6
Wheeze or whistling in the chest in last year	1.6	2.9	8.3	-2.9	-0.1	0.7
Mouth/teeth dental problems: Mouth ulcers	1.6	2.6	3.6	-1.9	-0.9	-1.8
Miserableness	1.6	2.8	7.2	-2.7	-0.3	1.1
Worry (Nagel 2018)	1.5	3.2	5.6	-2.4	1.1	1.7
Body Mass Index (BMI) (2010)	1.5	2.0	3.6	0.9	-1.3	-1.9
Type 2 Diabetes (T2D) (2018)	1.5	2.8	6.8	2.6	1.3	-0.3
Eye problems/disorders: Diabetes related eye disease	1.5	1.6	2.5	0.4	1.5	1.6
Severe depression (siblings)	1.5	1.7	2.9	1.7	-0.4	-1.4
Bilateral oophorectomy (both ovaries removed)	1.5	1.8	3.0	-1.5	-0.2	1.7
Medication: Ibuprofen (e.g. Nurofen)	1.5	2.0	2.7	-0.9	-1.7	-1.5
Number of full brothers	1.5	1.9	3.6	-1.9	-1.4	0.6
Commuting to job workplace: Car/motor vehicle	1.5	1.7	3.9	-0.8	-2.0	-0.8
Commuting to job workplace: Cycle	1.5	1.8	4.1	2.0	-0.6	1.0
Cholesterol lowering medication	1.5	2.3	3.9	0.3	2.0	-1.7
Rheumatoid Arthritis	1.4	2.0	4.9	0.9	-2.2	-0.4
Blood White Count	1.4	10.4	30.3	-0.5	-0.8	5.5
Mouth/teeth dental problems	1.4	2.1	4.2	2.1	0.9	1.2
Diabetes (self-reported)	1.4	2.2	5.5	1.0	2.3	-0.2
Medication: Simvastatin	1.4	2.1	3.0	1.6	1.7	-0.9
Neck or shoulder pain in last month	1.4	2.1	3.8	0.6	-1.9	-1.4
Mother’s age at death	1.4	1.7	4.3	-0.8	2.1	0.5
Breast Cancer	1.3	3.2	5.1	0.3	2.1	2.3
Lung FEV1/FVC ratio	1.3	6.7	19.1	4.4	0.8	-0.6
Neuroticism score	1.3	2.6	5.1	-2.3	-0.1	1.6
Time employed in main current job	1.3	1.5	4.4	0.4	-0.0	-2.1
Exposure to tobacco smoke at home	1.3	1.5	2.2	-1.4	-1.5	-0.4
Seen a psychiatrist for nerves, anxiety, tension or depression	1.3	1.7	3.9	-0.8	-2.0	-0.6
Medication: Ibuprofen	1.3	1.5	2.5	-0.9	-1.1	-1.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.3	1.5	3.0	-1.2	-0.4	1.7
Financial situation satisfaction	1.3	1.6	4.6	2.2	0.0	-0.4
High cholesterol (Self-reported)	1.3	2.3	5.4	0.3	2.3	-1.1
Average weekly beer plus cider intake	1.3	1.8	3.2	-1.5	-1.8	-0.2
Myopia	1.3	1.9	3.7	0.5	1.9	1.3
Supplements: Calcium	1.3	1.4	3.2	-1.8	-1.0	0.4
Maternal smoking around birth	1.2	1.8	4.0	-0.0	-1.2	-2.0
Diverticular disease/diverticulitis (self-reported)	1.2	1.4	4.1	0.2	0.0	-2.0
Mouth/teeth dental problems: Loose teeth	1.2	1.5	4.0	-2.0	-0.5	0.2
Ever had stillbirth, spontaneous miscarriage or termination	1.2	1.3	2.1	0.0	-1.5	1.3
Friendships satisfaction	1.2	1.5	1.8	1.1	-1.3	-1.3
Number of operations (self-reported)	1.2	1.8	3.2	-0.1	-1.5	-1.8
Ever had hysterectomy (womb removed)	1.1	1.3	2.8	-0.7	0.8	1.7
Vitamin and mineral supplements	1.1	1.5	2.8	1.7	1.0	0.9
Medication: Levothyroxine sodium	1.1	1.8	3.0	1.5	1.7	-0.5
Medication: Ramipril	1.1	1.4	1.6	1.0	1.3	1.3
Medication: Lansoprazole	1.1	1.2	1.6	-1.2	0.9	-1.1
Length of working week for main job	1.1	1.2	2.6	-0.7	-1.6	0.7
Qualifications: O levels/GCSEs or equivalent	1.1	1.7	4.5	2.1	0.6	-0.5
Qualifications: College or University degree	1.1	3.5	6.6	2.6	2.0	0.4
Number of full sisters	1.1	1.3	2.1	-1.4	0.5	-1.3
Handedness (chirality/laterality): Left-handed	1.1	1.3	3.0	-0.4	1.7	-0.8
Alcohol drinker status: Previous	1.1	1.3	2.5	1.6	-0.9	0.8
Hearing difficulty/problems: Yes	1.0	1.5	3.6	-0.6	-1.9	0.7
Medication for hormone replacement therapy	1.0	1.1	2.2	1.5	0.8	0.6
Relative age voice broke	1.0	1.5	2.8	1.7	-0.1	-1.3
Had other major operations	1.0	1.2	2.2	0.0	-1.2	-1.5
Alcohol intake versus 10 years previously	1.0	1.5	4.0	-2.0	-0.5	-0.7
Father’s age at death	1.0	1.4	3.1	1.8	-0.5	-0.9
Happiness	1.0	1.2	3.2	1.8	0.4	0.6
Tense / ‘highly strung’	1.0	1.6	4.6	-2.1	-0.1	0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	1.0	1.6	3.7	-1.9	-0.8	-0.7
Mouth/teeth dental problems: Bleeding gums	1.0	1.2	3.5	0.4	-0.2	-1.9
Age at first live birth	1.0	1.7	4.8	2.2	-0.4	0.5
Suffer from ‘nerves’	1.0	1.6	4.0	-2.0	-0.1	0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.0	1.2	3.0	0.6	1.7	-0.4
Loneliness, isolation	1.0	1.4	3.1	-0.7	-0.6	-1.8
Mineral and other dietary supplements	1.0	1.3	3.6	1.9	-0.6	-0.4
Osteoporosis (self-reported)	1.0	1.3	2.4	-0.0	1.2	1.5
Pain type(s) experienced in last month: Hip pain	1.0	1.3	3.6	-1.9	0.5	-0.0
Neuroticism (Nagel 2018)	0.9	2.1	5.5	-2.3	-0.4	0.8
Alzheimer’s Disease (in father)	0.9	1.0	2.9	-0.2	0.3	1.7
Alzheimer’s Disease (including proxy)	0.9	1.3	3.7	0.5	-0.2	1.9
Frequency of depressed mood in last 2 weeks	0.9	1.3	2.0	-1.3	-1.4	-0.4
Nervous feelings	0.9	1.7	4.8	-2.2	0.4	0.2
Breastfed as a baby	0.9	1.1	2.4	0.9	-1.6	-0.3
Hypothyroidism/myxoedema (self-reported)	0.9	1.7	2.8	1.4	1.7	-0.5
Worry too long after embarrassment	0.9	1.6	3.6	-1.0	-1.9	0.4
Medication: Blood pressure	0.9	1.7	1.8	1.3	1.3	1.3
Irritability	0.9	1.6	2.7	-1.6	-1.2	0.7
Ever used hormone-replacement therapy (HRT)	0.8	1.0	2.6	-0.5	0.5	-1.6
Medication: Co-codamol	0.8	1.0	1.8	-0.3	-1.0	-1.4
Serious illness, injury or assault of a close relative in last 2 years	0.8	1.0	2.1	-1.5	-0.8	0.4
Mouth/teeth dental problems: Dentures	0.8	1.3	2.4	-1.2	-1.6	0.0
Pulse wave Arterial Stiffness index	0.8	0.9	2.3	0.4	0.4	1.5
Glaucoma (self-reported)	0.8	0.9	1.7	-1.3	-0.9	-0.7
Arm fat-free mass (right)	0.8	4.2	11.2	3.3	1.0	0.7
Number of children fathered	0.8	1.0	1.7	-1.1	-1.3	-0.3
Health satisfaction	0.8	1.1	2.0	0.9	-0.6	-1.4
Family relationship satisfaction	0.8	1.0	2.4	1.5	-0.3	-0.6
Back pain experienced in last month	0.8	1.1	1.9	1.1	-1.4	0.4
Ever taken oral contraceptive pill	0.8	0.9	2.6	-0.0	-0.4	-1.6
Commuting to job workplace: Public transport	0.8	0.9	1.2	1.1	0.8	0.9
Alcohol drinker status: Never	0.8	1.0	1.5	0.1	-1.2	-1.1
Bipolar Disorder (2018)	0.7	1.2	2.4	-0.2	1.0	1.5
Bipolar Disorder (2011)	0.7	0.7	1.1	1.0	0.1	-1.0
Fasting Glucose	0.7	0.8	1.0	0.8	-0.9	-1.0
Schizophrenia (2014)	0.7	1.6	3.5	-0.9	-0.7	-1.9
Ulcerative Colitis	0.7	0.9	2.4	0.6	-0.3	1.6
Townsend deprivation index at recruitment	0.7	1.0	1.8	0.4	-1.1	-1.3
Serious illness, injury or assault to yourself	0.7	0.9	1.1	-1.0	-0.8	0.9
Fluid intelligence score	0.7	1.4	3.9	-0.6	0.2	2.0
Impedance of arm (right)	0.7	3.3	7.1	-2.7	-1.2	-1.1
Illnesses of mother	0.7	0.9	2.1	-0.5	-1.5	-0.6
Ever highly irritable/argumentative for 2 days	0.7	0.9	1.5	-1.0	1.2	0.5
Medication: Paracetamol	0.7	1.2	3.0	-1.7	-0.7	0.3
Pulse wave peak to peak time	0.7	0.9	2.3	-0.4	-0.5	-1.5
Migraine (self-reported)	0.7	0.8	1.9	-0.0	0.8	-1.4
Arm predicted mass (right)	0.7	3.8	10.0	3.2	0.9	0.7
Chest pain or discomfort	0.7	1.1	1.7	-1.3	-0.1	-1.2
Mood swings	0.7	1.2	1.5	-1.2	-1.2	-0.9
Smoking status: Current	0.7	1.1	2.1	-0.8	0.8	-1.4
Medication: Paracetamol	0.7	1.1	2.2	-1.5	0.0	1.0
Ever smoked	0.7	1.3	3.0	-0.4	-1.7	-0.9
Depression (Nagel 2018)	0.6	0.9	1.7	-0.7	-0.9	-1.3
Alzheimer’s Disease (in mother)	0.6	0.7	1.4	1.2	0.5	0.6
Irritable Bowel Disease (IBD)	0.6	1.4	3.4	0.3	-0.8	1.8
Ulcerative Colitis (UC)	0.6	1.1	2.8	0.1	-0.6	1.7
Hypothyroidism (self reported)	0.6	1.3	2.0	1.4	1.1	-0.9
Other serious medical condition/disability diagnosed by doctor	0.6	0.8	1.8	0.7	1.3	-0.2
Current tobacco smoking	0.6	1.0	1.5	-0.9	0.8	-1.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.8	1.7	-0.5	-0.8	-1.3
Age when periods started (menarche)	0.6	1.4	3.2	1.8	0.2	1.0
Stomach or abdominal pain in last month	0.6	0.7	1.5	0.2	-1.2	-0.7
Past tobacco smoking	0.6	1.1	2.3	-0.2	1.5	0.9
Had menopause	0.6	0.8	1.4	1.2	0.5	-0.8
Qualifications: A levels/AS levels or equivalent	0.6	1.3	3.1	1.8	0.1	-0.8
Impedance of arm (left)	0.6	2.7	5.1	-2.3	-1.5	-0.8
Pulse wave reflection index	0.6	0.7	2.1	-0.1	0.3	1.4
Medication: Ventolin 100micrograms inhaler	0.6	0.8	1.9	-1.4	0.7	-0.2
Medication for pain relief, constipation, heartburn	0.6	1.0	2.3	0.5	1.5	0.7
Pulse rate, automated reading	0.6	2.0	3.5	-0.1	1.6	1.9
Knee pain experienced in last month	0.6	1.0	1.4	1.2	-1.1	-0.5
Smoking status: Previous	0.6	0.9	1.7	0.7	-1.3	-0.7
Hearing aid user	0.6	0.6	0.7	0.8	0.8	0.8
Arm fat-free mass (left)	0.6	3.1	8.6	2.9	0.6	0.4
Unable to work because of sickness or disability	0.6	0.8	1.8	0.7	-0.1	-1.3
Arm predicted mass (left)	0.6	3.1	8.6	2.9	0.7	0.4
Age at First Birth	0.5	0.7	1.0	1.0	-1.0	-0.4
Primary Biliary Cirrhosis	0.5	0.7	1.5	-0.6	1.2	0.1
Triglycerides	0.5	0.8	1.1	1.1	0.9	-0.6
Blood Eosinophil Count	0.5	3.5	6.9	1.4	1.3	2.6
Blood Platelet Count	0.5	6.0	7.0	-2.5	-2.2	-2.6
BMI	0.5	2.7	7.0	2.6	-1.1	0.1
Respiratory disease	0.5	1.0	1.8	-0.5	1.0	-1.3
Neuroticism	0.5	1.2	2.0	-1.4	0.4	1.1
Chronotype (morning person)	0.5	1.2	2.7	1.6	0.1	-1.0
Sensitivity / hurt feelings	0.5	0.8	1.8	-1.4	-0.7	0.1
Impedance of leg (right)	0.5	2.5	6.6	-2.6	-0.5	0.8
Multivitamins +/- minerals	0.5	0.6	0.7	-0.8	-0.7	-0.7
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.8	1.9	-1.4	-0.7	-0.3
Hearing difficulty/problems with background noise	0.5	0.8	1.6	0.5	-0.7	1.3
Trunk fat-free mass	0.5	2.7	7.0	2.6	1.1	0.2
Hip circumference	0.5	2.0	3.1	0.7	-1.5	-1.8
Medication: Cholesterol lowering	0.5	0.7	1.6	1.2	0.8	-0.1
Trunk predicted mass	0.5	2.9	7.4	2.7	1.1	0.2
Shortness of breath walking on level ground	0.5	0.5	1.3	-0.4	-0.4	-1.2
Medication: Allopurinol	0.5	0.7	2.0	-0.2	1.4	0.2
Whole body fat-free mass	0.5	2.6	7.3	2.7	0.8	-0.0
Whole body water mass	0.5	3.0	8.3	2.9	0.8	0.0
Number of self-reported non-cancer illnesses	0.5	0.9	2.6	-0.0	1.6	-0.4
Medication: Bendroflumethiazide	0.5	0.8	2.1	-0.4	0.4	1.4
Pain experienced in last month	0.5	0.9	1.5	1.0	1.2	-0.3
Impedance of whole body	0.5	2.8	6.5	-2.5	-1.4	-0.1
Bipolar Disorder or Schizophrenia	0.4	0.9	2.1	-0.1	-0.8	-1.5
Major Depression (MDD)	0.4	0.5	0.8	-0.8	0.9	-0.1
Relative age of first facial hair	0.4	0.9	1.6	0.2	1.3	-1.0
Hand grip strength (right)	0.4	1.2	2.4	0.4	1.5	1.0
Sitting height	0.4	2.9	8.2	2.9	-0.1	-0.8
Impedance of leg (left)	0.4	1.9	4.8	-2.2	-0.5	0.8
Financial difficulties in last 2 years	0.4	0.5	1.1	1.0	-0.1	-0.7
Depression (self-reported)	0.4	0.5	1.2	1.1	0.3	-0.6
Hair/balding pattern: Pattern 4	0.4	0.9	2.1	0.8	0.3	1.4
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.4	1.3	0.0	0.2	1.1
Medication: Seretide 50 evohaler	0.4	0.5	0.6	-0.8	-0.8	-0.5
Alcohol intake frequency.	0.4	0.8	1.4	-1.2	-0.9	0.6
Age at last live birth	0.4	0.6	1.5	1.2	-0.1	-0.4
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	1.0	0.6	1.0	-0.3
Supplements: Vitamin C	0.4	0.5	0.7	-0.7	-0.8	-0.5
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.9	2.2	0.2	-1.5	-0.7
Leg fat-free mass (right)	0.4	2.1	6.2	2.5	0.5	-0.2
Leg predicted mass (right)	0.4	2.3	6.4	2.5	0.5	-0.3
Wears glasses or contact lenses	0.4	0.4	0.9	-0.3	-0.9	-0.6
Risk taking	0.4	0.6	1.4	1.2	-0.5	0.2
Ever depressed for a whole week	0.4	0.5	0.7	-0.8	-0.6	-0.6
Crohns Disease (2017)	0.3	0.7	1.1	-0.4	-1.0	1.1
Verbal and Numeric Reasoning (VNR)	0.3	0.8	1.4	-1.0	-0.0	1.2
Ovarian Cancer	0.3	0.4	1.0	-1.0	0.3	0.1
Crohns Disease (2012)	0.3	0.5	1.3	-0.5	-0.1	1.2
HDL Cholesterol	0.3	0.5	0.7	-0.6	-0.8	-0.6
LDL Cholesterol	0.3	0.5	1.4	0.3	-0.1	-1.2
Lupus	0.3	0.5	1.2	0.3	-0.5	1.1
Systolic Blood Pressure	0.3	1.5	3.8	-2.0	-0.5	0.6
Number of treatments/medications taken	0.3	0.6	1.8	-0.2	1.3	-0.2
Average weekly spirits intake	0.3	0.4	0.8	-0.7	-0.9	0.0
Diabetes (father)	0.3	0.4	0.7	-0.5	0.9	0.5
Leg fat-free mass (left)	0.3	1.6	4.5	2.1	0.4	-0.3
Fed-up feelings	0.3	0.6	1.2	-1.1	0.4	0.7
Qualifications: CSEs or equivalent	0.3	0.5	1.0	-0.4	-1.0	-0.4
High blood pressure (mother)	0.3	0.4	0.6	-0.8	-0.7	0.4
Leg predicted mass (left)	0.3	1.7	4.7	2.2	0.5	-0.3
Qualifications: None of the above	0.3	0.6	1.3	-1.1	0.2	0.7
Noisy workplace	0.3	0.4	0.9	-0.4	0.9	0.3
Asthma	0.3	0.5	1.2	0.0	0.7	-1.1
Prospective memory result	0.3	0.4	0.6	0.2	0.7	-0.8
High blood pressure (siblings)	0.3	0.5	0.7	0.8	0.8	-0.4
Comparative body size at age 10	0.3	0.8	1.9	1.4	-0.6	-0.2
Medication: Blood pressure	0.3	0.6	1.1	0.8	1.0	0.3
Had major operations	0.3	0.4	0.8	-0.3	-0.9	-0.5
Illnesses of father: Heart disease	0.3	0.4	0.5	-0.7	0.7	0.1
Long-standing illness, disability or infirmity	0.3	0.4	0.6	0.4	-0.7	-0.8
Medication for cholesterol	0.3	0.4	0.9	-0.9	-0.6	-0.2
Medication: Aspirin	0.3	0.4	0.5	0.6	0.5	0.7
Illnesses of father: None of the above (group 1)	0.3	0.4	1.3	1.1	0.0	0.1
Average weekly champagne plus white wine intake	0.3	0.4	0.8	0.6	-0.9	-0.3
Tinnitus: Yes, now most or all of the time	0.3	0.3	0.8	-0.4	-0.1	0.9
Illnesses of father: High blood pressure	0.3	0.3	0.9	-0.3	-0.9	0.2
Basal metabolic rate	0.3	1.9	5.5	2.3	0.5	-0.0
Fractured/broken bones in last 5 years	0.3	0.3	0.5	0.2	-0.7	-0.7
Coronary Artery Disease (CAD)	0.2	0.2	0.3	0.6	0.5	0.2
Type 2 Diabetes (T2D) (2012)	0.2	0.3	0.5	-0.5	0.3	-0.7
Tanning	0.2	1.8	2.7	-1.5	-0.8	-1.6
Hand grip strength (left)	0.2	0.6	1.0	-0.8	1.0	0.3
Waist circumference	0.2	0.6	1.3	1.1	0.6	0.3
Forced vital capacity (FVC)	0.2	0.9	1.7	-1.3	-0.8	0.3
Illnesses of siblings	0.2	0.3	0.5	0.4	-0.3	0.7
Arm fat percentage (right)	0.2	0.8	1.8	-0.4	-1.4	-0.7
Pulse rate	0.2	0.3	0.6	0.5	0.1	0.8
Peak expiratory flow (PEF)	0.2	0.5	1.5	1.2	0.2	-0.1
Blood clot in the leg (DVT)	0.2	0.2	0.5	-0.3	-0.3	-0.7
Headache pain in last month	0.2	0.4	0.9	0.4	-0.1	-0.9
Medication for cholesterol, blood pressure or diabetes	0.2	0.4	0.7	-0.8	-0.7	0.1
Medication: Amlodipine	0.2	0.2	0.6	-0.3	0.8	0.1
Birth weight	0.2	0.4	0.6	0.5	0.8	0.6
Forced vital capacity (FVC), Best measure	0.2	0.6	0.7	-0.8	-0.8	0.6
Body fat percentage	0.2	0.6	1.7	-0.5	-1.3	-0.0
Leg fat percentage (right)	0.2	0.6	0.6	-0.8	-0.7	0.7
Exposure to tobacco smoke outside home	0.2	0.3	0.8	0.0	0.0	-0.9
Illnesses of siblings: Diabetes	0.2	0.2	0.3	0.4	0.5	-0.6
Arm fat percentage (left)	0.2	0.6	1.7	-0.1	-1.3	-0.4
Commuting to job workplace: Walk	0.2	0.3	0.4	0.6	0.6	-0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.2	0.7	-0.1	0.1	0.8
Asthma (self-reported)	0.2	0.5	1.0	0.2	1.0	-0.6
Osteoarthritis (self-reported)	0.2	0.3	0.3	-0.4	0.6	0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.5	1.3	0.3	1.2	-0.3
Medication: Lisinopril	0.2	0.3	0.8	-0.2	0.9	-0.0
Medication: Atorvastatin	0.2	0.2	0.5	0.3	-0.3	-0.7
Age started oral contraceptive pill	0.2	0.2	0.6	0.1	0.1	-0.8
Diastolic blood pressure, automated reading	0.2	0.5	1.1	1.0	0.5	0.4
Deep venous thrombosis (DVT) (self-reported)	0.2	0.2	0.5	-0.3	-0.4	-0.7
Depressed Affect (Nagel 2018)	0.1	0.3	0.8	-0.9	-0.1	-0.0
Intelligence (Savage-Jansen 2018)	0.1	0.3	0.5	-0.2	-0.4	0.7
Schizophrenia vs Biploar Disorder	0.1	0.1	0.2	-0.4	-0.1	-0.2
Blood Red Count	0.1	0.5	0.9	0.9	0.1	0.8
Height	0.1	2.0	3.4	0.2	1.9	1.6
Allergy or Eczema	0.1	0.2	0.4	0.2	0.1	0.7
Cardiovascular Disease	0.1	0.2	0.2	0.4	0.4	-0.4
Lung FVC	0.1	0.5	1.2	-1.1	-0.5	0.1
Supplements: Zinc	0.1	0.1	0.2	-0.4	-0.5	-0.2
Trunk fat percentage	0.1	0.6	1.6	-0.4	-1.2	0.2
Average weekly fortified wine intake	0.1	0.2	0.3	0.5	-0.4	-0.1
Hayfever, allergic rhinitis or eczema	0.1	0.2	0.5	0.2	0.4	0.7
Body mass index (BMI)	0.1	0.4	0.8	0.6	-0.9	-0.2
Trunk fat mass	0.1	0.3	0.5	0.5	-0.7	0.1
Number of incorrect matches in round	0.1	0.2	0.4	0.2	-0.6	-0.4
Ever unenthusiastic/disinterested for a whole week	0.1	0.2	0.4	-0.2	0.6	-0.3
Allergy	0.1	0.2	0.4	-0.3	0.0	0.6
Weight	0.1	0.7	2.0	1.4	-0.2	-0.2
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.2	0.6	-0.8	-0.1	-0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.4	0.7	0.4	-0.8	0.6
Arm fat mass (right)	0.1	0.4	0.6	0.7	-0.7	-0.4
Standing height	0.1	1.2	2.4	1.6	1.1	-0.2
Gout (self-reported)	0.1	0.1	0.3	-0.0	0.5	-0.0
Medication: Omeprazole	0.1	0.2	0.3	-0.4	-0.2	0.6
Whole body fat mass	0.1	0.3	0.4	0.7	-0.7	-0.2
Leg fat mass (right)	0.1	0.2	0.3	0.5	-0.6	0.2
Comparative height size at age 10	0.1	0.5	0.9	0.2	0.9	0.8
Medication: Aspirin	0.1	0.2	0.3	0.5	-0.2	0.5
Hypertension (Self-reported)	0.1	0.3	0.6	0.8	0.3	0.3
Qualifications: nursing, teaching	0.1	0.2	0.6	0.1	-0.7	0.2
Arm fat mass (left)	0.1	0.6	1.0	1.0	-0.8	-0.2
Eye problems/disorders: Glaucoma	0.1	0.2	0.5	-0.7	-0.1	0.1
Leg fat percentage (left)	0.1	0.5	0.7	-0.6	-0.7	0.8
Vascular/heart problems diagnosed by doctor	0.1	0.4	0.6	-0.4	-0.8	-0.6
Medication: Omeprazole (e.g. Zanprol)	0.1	0.1	0.2	-0.4	-0.2	0.3
Leg fat mass (left)	0.1	0.3	0.5	0.7	-0.5	0.2
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0
Heel T-Score	0.0	0.2	0.3	0.5	-0.1	0.4
Smoking Status	0.0	0.1	0.2	-0.3	0.2	-0.4
Hair Pigment	0.0	0.4	0.9	-0.3	-0.9	-0.3
Systolic blood pressure, automated reading	0.0	0.0	0.0	0.1	0.1	0.2
Pack years adult smoking proportion	0.0	0.1	0.1	0.1	0.3	0.3
Heel bone mineral density (BMD) T-score, automated (left)	0.0	0.1	0.2	-0.3	0.5	0.1
High blood pressure	0.0	0.1	0.2	0.4	0.1	0.3
Supplements: Glucosamine	0.0	0.1	0.1	0.2	0.0	0.4
Heel bone mineral density (BMD) T-score, automated (right)	0.0	0.1	0.2	-0.5	0.2	0.0
Forced expiratory volume in 1-second (FEV1)	0.0	0.1	0.2	-0.0	-0.4	0.2
Overall health rating	0.0	0.0	0.0	-0.0	-0.2	-0.1
Breast cancer (self-reported)	0.0	0.1	0.2	-0.4	0.0	-0.0
Pack years of smoking	0.0	0.0	0.1	-0.2	0.2	-0.0

Hub : Genes

GPR116

Models

Trait associations