Hub : Genes

GPR135

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.0850	0.0300	1.1e-04	0.092	NA	0.056	NA	0.068	6.0e-08	NA	2.3e-05	NA	3.2e-06
2	GTEx	Artery Aorta	0.0960	0.0450	2.4e-03	0.014	NA	0.024	NA	0.019	5.3e-02	NA	1.8e-02	NA	2.9e-02
3	GTEx	Artery Tibial	0.1024	0.0326	6.8e-07	0.059	NA	0.063	NA	0.074	2.1e-05	NA	1.1e-05	NA	1.8e-06
4	GTEx	Brain Cerebellum	0.1210	0.0510	2.7e-03	0.016	NA	0.034	NA	-0.008	1.1e-01	NA	3.6e-02	NA	6.6e-01
5	GTEx	Breast Mammary Tissue	0.1220	0.0570	8.8e-03	0.011	NA	0.025	NA	0.035	8.1e-02	NA	1.8e-02	NA	6.5e-03
6	GTEx	Breast Mammary Tissue (Male)	0.0389	0.0645	3.1e-01	-0.005	NA	-0.006	NA	0.008	4.4e-01	NA	4.6e-01	NA	2.1e-01
7	GTEx	Breast Mammary Tissue (Female)	0.0726	0.0591	1.3e-01	0.028	NA	-0.009	NA	0.002	5.0e-02	NA	7.7e-01	NA	2.7e-01
8	GTEx	Cells EBV-transformed lymphocytes	0.3320	0.0910	3.3e-04	0.038	NA	0.146	NA	0.093	2.1e-02	NA	1.7e-05	NA	5.9e-04
9	GTEx	Cells Transformed fibroblasts	0.1120	0.0410	7.2e-05	0.127	NA	0.100	NA	0.119	9.6e-10	NA	5.9e-08	NA	3.2e-09
10	GTEx	Colon Transverse	0.1530	0.0590	4.1e-04	0.170	NA	0.118	NA	0.108	1.7e-08	NA	3.1e-06	NA	7.9e-06
11	GTEx	Esophagus Mucosa	0.1010	0.0390	2.0e-03	-0.002	NA	0.020	NA	0.015	5.0e-01	NA	1.6e-02	NA	3.0e-02
12	GTEx	Esophagus Muscularis	0.1170	0.0450	9.1e-05	0.106	NA	0.053	NA	0.075	6.0e-07	NA	3.7e-04	NA	2.6e-05
13	GTEx	Heart Atrial Appendage	0.1410	0.0490	6.0e-05	0.082	NA	0.070	NA	0.075	1.5e-04	NA	4.4e-04	NA	3.1e-04
14	GTEx	Ovary	0.2350	0.0780	3.7e-04	0.176	NA	0.189	NA	0.194	4.2e-05	NA	2.1e-05	NA	1.7e-05
15	GTEx	Pituitary	0.1780	0.0720	1.8e-03	0.135	NA	0.117	NA	0.117	3.0e-04	NA	7.3e-04	NA	7.3e-04
16	METSIM	Adipose	0.0505	0.0192	8.9e-05	0.032	0.029	0.023	0.029	0.023	1.0e-05	3.2e-05	1.7e-04	3.3e-05	2.0e-04
17	TCGA	Head and Neck Squamous Cell Carcinoma	0.0242	0.0131	6.0e-04	0.039	0.026	0.030	NA	0.033	2.9e-05	5.6e-04	2.4e-04	NA	1.1e-04
18	TCGA	Brain Lower Grade Glioma	0.0679	0.0314	1.6e-08	0.087	0.076	0.076	NA	0.075	4.0e-10	5.3e-09	5.7e-09	NA	7.7e-09
19	TCGA	Thyroid Carcinoma	0.0640	0.0340	2.8e-06	0.024	0.048	0.039	NA	0.041	1.9e-03	1.7e-05	9.9e-05	NA	6.6e-05

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19
Bipolar Disorder (2018)	3.5	5.6	10.2	2.5	1.3	3.2	2.8	2.0	-0.2	2.9	1.1	2.6	3.2	1.9	2.6	3.0	2.5	2.1	-1.3	-2.1	2.4	2.7
Bipolar Disorder or Schizophrenia	1.1	2.7	7.3	1.5	1.2	2.0	1.9	-1.5	0.3	-0.9	-2.7	1.2	1.1	-1.0	1.6	1.3	1.4	1.2	-2.1	-2.1	2.0	2.3
Depressed Affect (Nagel 2018)	1.4	2.9	7.7	2.3	0.2	2.0	1.4	0.5	2.1	0.5	0.4	1.7	1.3	1.1	2.8	1.6	1.8	2.6	-1.1	-1.6	2.1	2.0
Depression (Nagel 2018)	3.0	4.6	12.3	2.8	2.0	2.7	1.3	0.7	3.5	0.4	-0.9	2.7	1.3	1.4	3.1	2.0	2.3	2.5	-0.8	-2.2	2.5	2.0
Intelligence (Savage-Jansen 2018)	2.6	8.0	22.3	-2.8	-3.5	-2.9	-2.4	-2.9	-0.9	-4.7	-2.9	-3.5	-2.3	-2.3	-3.5	-3.3	-3.0	-2.4	1.6	2.6	-2.3	-1.6
Neuroticism (Nagel 2018)	2.5	5.9	12.2	3.0	2.1	3.2	2.4	0.4	2.2	0.7	-0.5	2.2	2.1	1.7	3.5	2.6	2.5	3.3	-1.9	-2.6	3.2	3.0
Schizophrenia (2018)	1.5	3.1	18.9	-0.1	0.5	-0.0	0.2	-3.6	0.6	-3.5	-4.3	-0.5	-1.1	-2.8	-0.0	-0.8	-0.3	-0.2	-1.6	-0.9	0.6	0.8
Schizophrenia vs Biploar Disorder	2.0	2.7	13.0	-0.3	1.3	-0.3	-0.2	-2.9	1.5	-3.2	-3.6	-0.4	-1.5	-2.6	-0.1	-1.5	-0.4	-0.1	-1.7	-1.0	0.2	0.3
Worry (Nagel 2018)	2.2	4.6	8.5	2.5	2.4	2.9	2.0	0.5	2.3	1.2	-1.0	2.0	1.8	0.8	2.7	2.4	2.2	2.2	-1.5	-2.4	2.9	2.8
Alzheimer’s Disease (in mother)	0.4	0.5	3.1	0.5	-0.3	0.1	0.0	-0.2	0.1	0.1	1.8	1.3	1.1	0.4	0.3	0.5	0.8	0.0	0.2	0.8	1.1	0.4
Alzheimer’s Disease (in father)	0.5	0.5	1.2	-0.7	-0.7	-0.7	-0.5	-1.1	0.1	-0.4	-0.1	-0.4	-1.0	-0.8	-0.6	-1.0	-0.7	-0.9	-0.5	-0.0	-0.9	-1.0
Alzheimer’s Disease (including proxy)	0.2	0.2	1.9	-0.4	-0.8	-0.5	-0.2	-0.3	-0.1	0.0	1.4	0.2	-0.2	-0.2	-0.5	-0.5	-0.2	-0.6	0.1	0.2	-0.0	-0.4
Crohns Disease (2017)	0.2	0.4	1.8	0.4	-0.9	-0.2	0.1	-0.4	-0.7	-0.4	1.4	0.4	1.0	0.4	0.0	0.3	0.6	-0.1	0.2	0.7	0.5	0.8
Irritable Bowel Disease (IBD)	0.1	0.3	2.3	0.4	-0.4	-0.0	0.6	0.2	-1.1	0.2	1.5	0.1	0.8	0.4	0.2	0.3	0.6	0.4	-0.0	0.0	0.4	0.8
Ulcerative Colitis (UC)	0.2	0.4	1.1	0.3	0.9	0.3	1.1	0.7	-1.0	0.7	0.9	-0.4	0.4	0.2	0.3	0.2	0.4	0.6	-0.1	-0.8	0.4	0.8
Major Depression (MDD)	1.1	1.4	7.9	-0.4	-1.5	-0.3	-1.1	-1.5	1.7	-2.2	-2.8	-0.9	-1.1	-0.4	-0.2	-0.5	-0.9	-0.5	0.9	0.5	-0.3	-0.4
Reaction Time	0.3	0.6	1.8	0.7	0.9	0.8	0.8	0.6	-1.3	0.6	0.2	0.6	1.2	0.4	0.5	1.1	0.9	0.8	0.0	0.0	1.0	1.1
Verbal and Numeric Reasoning (VNR)	1.0	2.4	8.1	-1.4	-1.7	-1.2	-1.5	-1.4	0.8	-2.9	-2.5	-2.1	-1.8	-1.3	-1.5	-1.3	-1.8	-1.2	0.7	1.1	-1.2	-0.8
Breast Cancer	0.4	0.9	5.1	0.5	0.4	0.1	0.6	-1.2	1.0	-0.7	-1.1	0.4	-0.7	-0.9	1.1	-0.6	0.3	0.8	-2.2	-1.7	0.3	0.3
Ovarian Cancer	0.9	1.2	3.3	1.3	0.5	0.9	1.5	-0.2	0.7	-0.1	0.7	0.7	0.8	0.1	1.1	1.3	1.2	1.4	-1.2	-1.8	1.1	1.8
Prostate Cancer	0.2	0.2	1.0	-0.1	0.9	0.1	-0.5	0.2	0.8	0.0	1.0	-0.3	0.2	-0.7	-0.4	-0.4	-0.2	-0.3	0.1	0.3	0.4	0.5
Age at First Birth	0.3	0.5	2.0	-0.7	-0.8	-0.9	-0.7	-1.4	0.1	-0.7	-0.7	0.2	-0.7	-0.8	-0.8	-0.6	-0.5	-0.7	0.3	0.3	-0.5	-1.0
Bipolar Disorder (2011)	2.1	2.0	5.1	1.6	-0.3	2.0	1.4	1.6	-0.2	1.8	0.1	1.0	2.2	1.7	1.5	1.2	1.7	1.3	-0.2	-0.8	1.7	1.7
Body Mass Index (BMI) (2010)	1.4	1.9	4.9	1.4	1.5	1.4	1.3	0.7	-0.3	2.2	1.3	1.5	1.8	0.9	1.6	1.8	1.5	1.2	-0.8	-0.8	1.4	1.4
Coronary Artery Disease (CAD)	0.5	0.6	2.3	-0.7	-1.5	-0.7	-0.7	-0.5	0.7	-1.0	-0.5	-0.9	-1.3	-0.7	-0.2	-0.7	-0.9	0.3	0.2	-0.0	-0.8	-0.8
Crohns Disease (2012)	0.3	0.4	3.5	0.1	-0.8	-0.3	-0.6	0.3	-0.4	0.0	1.9	0.8	0.6	0.7	0.0	-0.0	0.5	-0.4	0.4	1.2	0.2	-0.2
Mean Putamen Volume	1.6	1.8	3.8	-1.3	-1.6	-1.4	-1.5	-1.4	0.5	-1.6	-1.4	-1.2	-2.0	-1.0	-1.1	-1.5	-1.5	-1.5	1.5	0.9	-1.1	-1.1
Fasting Glucose	0.8	0.9	6.3	0.8	0.6	0.5	-0.3	-0.1	2.5	-0.9	-0.5	1.6	-0.1	0.2	1.3	0.2	0.8	1.4	-0.7	-0.6	1.0	0.1
HbA1C	0.4	0.4	3.6	0.1	1.9	-0.2	-0.3	0.7	0.5	0.6	0.6	0.6	0.3	0.5	0.2	-0.7	0.2	-0.2	-0.8	0.1	-0.4	-0.5
HDL Cholesterol	1.0	1.7	8.2	-0.7	-2.5	-0.9	-0.3	-2.5	-1.0	-2.9	-0.8	-0.6	-0.6	-1.5	-0.5	-1.6	-0.4	-0.8	0.7	0.7	-0.7	-0.5
LDL Cholesterol	0.7	1.0	3.6	-1.0	0.9	-1.2	-1.1	0.6	-0.9	0.5	-1.9	-1.3	-0.3	0.1	-0.8	-1.3	-0.9	-1.5	0.0	1.2	-0.9	-1.0
Lupus	0.9	1.3	5.3	-1.3	-0.6	-0.8	-0.0	-1.3	-2.1	-0.3	-1.5	-2.3	-0.9	-1.0	-1.0	-1.2	-1.6	-0.9	0.1	0.6	-1.0	-0.1
Neuroticism (2016)	0.2	0.3	1.6	0.4	0.1	0.6	0.5	-0.6	-0.2	0.0	-1.3	-0.1	0.2	-0.6	0.6	-0.4	0.2	0.5	-0.8	-0.7	0.4	0.9
Primary Biliary Cirrhosis	1.8	2.6	10.2	1.3	2.2	1.4	1.9	-1.7	0.5	-1.3	-1.5	1.2	0.7	-1.3	1.3	0.4	1.3	1.2	-3.2	-2.6	1.3	1.6
Rheumatoid Arthritis	0.5	0.7	5.8	0.2	1.0	0.7	1.2	0.7	-2.4	0.6	-0.5	-0.8	1.1	0.2	-0.6	0.7	0.4	0.3	-0.1	-0.4	0.5	0.9
Schizophrenia (2014)	1.1	2.5	19.0	0.2	0.8	0.4	0.6	-2.8	0.7	-2.4	-4.4	-0.9	-0.8	-2.4	0.2	-0.5	-0.2	-0.3	-1.0	-1.2	1.0	1.5
Triglycerides	0.6	1.0	5.2	-0.4	0.8	-0.5	-0.4	2.3	-1.5	2.1	1.6	0.2	0.6	0.4	-0.8	-0.0	-0.2	-0.8	0.2	1.1	-0.5	-0.6
Type 2 Diabetes (T2D) (2012)	0.4	0.5	3.4	0.2	-1.0	-0.4	-0.8	0.6	0.3	0.3	1.9	0.6	0.2	0.7	-0.3	0.5	-0.1	0.1	1.0	1.0	0.2	-0.6
Ulcerative Colitis	0.3	0.4	2.8	0.1	1.1	0.2	0.8	0.8	-1.7	0.6	0.5	-0.6	0.5	0.5	-0.1	0.2	0.4	0.4	-0.6	-0.3	0.1	0.1
Blood Eosinophil Count	0.3	2.5	6.3	-1.8	-1.5	-1.5	-1.8	0.9	-1.6	1.5	1.2	-0.6	-0.1	0.5	-1.4	-1.6	-1.2	-2.0	2.0	2.5	-1.8	-2.2
Blood Platelet Count	0.4	5.2	12.9	2.8	1.7	2.0	1.2	0.2	2.8	0.2	3.6	2.4	2.3	1.6	3.0	2.5	2.5	2.7	-1.0	-0.8	3.2	2.6
Blood Red Count	0.4	4.1	9.3	-2.2	-2.6	-2.5	-2.8	-1.2	0.2	-1.6	1.1	-1.7	-1.6	-1.4	-1.8	-3.1	-2.1	-2.1	0.3	2.7	-2.3	-2.4
Blood White Count	0.1	0.5	6.1	-0.0	-0.9	-0.1	-0.3	0.9	-0.5	0.7	2.5	0.1	0.7	0.6	0.0	-0.2	0.2	0.4	0.2	0.8	-0.2	-0.2
Heel T-Score	0.4	3.1	14.4	0.2	-1.0	0.2	-0.4	3.6	0.8	2.7	2.9	0.1	0.4	3.8	-0.1	1.6	0.2	0.5	2.9	0.8	-0.4	-1.0
BMI	1.4	8.3	37.4	2.9	1.0	2.5	2.3	3.5	-0.3	3.8	6.1	3.6	3.5	3.2	2.6	2.6	3.1	2.1	-1.1	-1.2	2.1	1.5
Height	1.3	25.1	79.7	-5.2	-3.5	-4.0	-3.0	-7.0	-1.1	-6.4	-8.9	-5.0	-6.2	-6.2	-4.4	-6.1	-5.3	-4.0	-0.1	0.7	-4.9	-3.6
Waist Hip Ratio (WHR)	0.2	0.8	3.0	-0.7	0.1	-1.3	-0.5	-0.3	-1.6	-0.1	0.5	0.5	-0.1	-1.3	-0.3	-1.7	-0.2	-1.0	-0.9	1.2	-0.4	-1.1
Systolic Blood Pressure	0.2	1.2	8.3	0.1	-0.4	-0.5	0.3	-2.0	0.1	-2.9	0.3	-0.4	-0.5	-2.0	0.0	-0.8	0.0	-0.0	-1.4	-0.6	0.3	1.3
Smoking Status	2.4	5.8	13.0	3.1	1.9	3.0	2.5	-0.1	2.1	0.6	-0.3	2.4	2.5	2.2	3.6	2.7	3.0	2.3	-1.6	-2.4	3.0	2.9
Allergy or Eczema	0.3	0.8	7.7	-0.5	-0.9	-0.5	0.3	0.7	-2.8	0.9	1.6	-0.1	0.8	0.1	-0.6	0.2	-0.0	-0.6	0.2	1.0	-0.4	-0.2
Cardiovascular Disease	0.8	2.5	7.6	1.8	0.6	1.5	1.5	0.2	1.5	0.4	2.8	2.3	0.9	-0.2	2.1	1.3	1.6	0.9	-2.1	-1.9	1.7	1.9
Hypothyroidism (self reported)	0.1	0.3	1.0	-0.3	0.4	0.0	-0.4	1.0	0.6	0.9	-0.7	-0.5	-0.7	0.5	-0.5	0.1	-0.8	-0.4	0.2	-0.1	-0.6	-0.8
Respiratory disease	0.5	1.1	2.9	-1.2	-1.0	-1.4	-0.9	-0.4	-1.4	-0.8	-0.3	-0.7	-0.6	-0.6	-1.3	-1.6	-0.9	-0.9	0.2	1.0	-1.7	-1.5
Type 2 Diabetes (T2D) (2018)	0.2	0.3	2.4	-0.1	-1.6	-0.2	-0.6	0.4	0.3	0.1	0.4	0.5	0.1	0.2	-0.3	-0.3	0.1	0.2	0.6	0.6	-0.1	-0.8
Lung FEV1/FVC ratio	0.7	3.7	7.8	-2.1	-2.6	-2.3	-2.8	-0.4	0.4	0.4	-1.6	-1.3	-2.3	-1.0	-1.8	-1.7	-2.3	-2.2	1.7	2.0	-2.2	-2.7
Lung FVC	3.4	17.5	28.4	5.1	5.2	4.9	4.9	0.9	1.7	1.3	2.9	4.4	4.4	2.1	4.1	5.3	4.9	4.0	-4.0	-4.2	5.3	5.2
Neuroticism	2.9	6.9	12.4	3.2	2.5	3.0	2.9	1.0	2.2	1.4	-0.3	2.4	2.0	1.1	3.5	2.8	2.8	3.4	-2.4	-3.1	3.5	3.2
Chronotype (morning person)	0.4	0.9	2.5	-1.4	-0.3	-1.0	-0.7	-0.2	-0.2	-0.0	0.3	-1.0	-1.6	-0.8	-0.7	-1.5	-1.4	-0.6	0.1	0.0	-1.4	-1.4
Hair Pigment	0.1	2.9	10.9	-1.9	-0.4	-2.0	-1.1	-1.9	0.4	-1.3	-1.1	-1.4	-2.6	-3.3	-1.7	-2.4	-1.9	-1.3	-0.6	0.1	-1.8	-1.3
Tanning	0.2	1.9	5.5	1.4	0.9	1.4	1.8	0.3	-1.9	0.8	1.0	1.0	2.3	1.2	0.7	1.3	1.8	1.2	0.2	-0.2	1.8	2.0
Hand grip strength (left)	0.1	0.4	2.4	-0.2	0.3	0.3	0.3	-1.5	-0.6	-1.1	-1.6	-0.1	0.1	-0.0	-0.3	-0.4	0.0	-0.1	0.3	-0.1	-0.1	0.1
Number of treatments/medications taken	0.4	0.7	2.7	-0.9	-1.1	-0.7	-1.3	0.9	0.1	0.8	-0.0	-0.2	-0.3	0.1	-0.7	-0.7	-0.9	-0.5	0.6	1.0	-1.6	-1.4
Average weekly spirits intake	1.3	1.6	7.0	0.0	0.4	0.1	-0.4	2.3	-1.6	2.1	2.6	1.1	1.4	1.5	-0.4	0.7	0.4	-0.5	1.2	1.7	-0.2	-0.7
Sensitivity / hurt feelings	1.6	2.7	6.2	1.9	1.8	2.0	1.8	1.1	1.3	0.4	-0.3	1.2	1.3	2.1	1.7	2.0	1.5	2.5	-0.8	-1.9	2.1	1.6
Frequency of depressed mood in last 2 weeks	3.3	4.6	8.5	2.8	2.2	2.9	1.5	0.5	2.4	0.1	-1.8	2.3	1.8	1.2	2.4	2.5	2.4	2.9	-0.4	-1.7	2.9	2.5
Hearing difficulty/problems: Yes	0.5	0.8	2.8	0.7	1.5	0.3	0.6	-0.4	1.4	-0.9	-1.7	0.8	-0.1	-0.2	0.8	0.7	0.6	1.2	-1.1	-1.1	0.7	0.3
Relative age of first facial hair	0.1	0.3	1.5	-0.4	1.2	0.1	-0.2	-0.4	-0.5	0.3	-1.2	-0.4	-0.3	-0.8	-0.0	0.1	-0.4	-0.6	0.0	0.1	-0.3	-0.2
Other serious medical condition/disability diagnosed by doctor	0.6	0.8	5.9	-0.8	0.4	-0.3	0.4	-0.7	-2.4	-0.8	-0.4	0.0	-0.1	-1.6	-0.7	-0.4	-0.4	-0.9	-1.2	-0.1	-0.7	-0.1
Ever used hormone-replacement therapy (HRT)	0.7	0.9	3.9	-0.7	-1.5	-0.6	-0.8	-1.5	0.0	-2.0	-1.3	-0.9	-0.9	-0.0	-0.8	-0.4	-0.9	-0.2	1.1	0.5	-0.6	-0.6
Ever had hysterectomy (womb removed)	0.9	1.0	2.3	1.0	0.7	1.2	1.3	0.8	-1.1	0.6	1.0	0.6	1.5	0.7	0.7	1.0	1.1	0.9	-0.3	-0.3	1.4	1.5
Systolic blood pressure, automated reading	0.2	0.5	2.9	0.1	-1.0	-0.4	-0.2	-0.9	-0.2	-1.7	1.7	-0.4	0.0	-0.5	0.4	-0.5	0.2	0.1	-0.4	0.3	0.3	0.8
Eye problems/disorders: Diabetes related eye disease	0.4	0.5	1.8	-0.5	-0.3	-0.9	-0.6	-0.9	0.2	-1.4	0.1	-0.5	-1.4	-0.9	-0.5	-0.6	-0.8	-0.4	-0.0	-0.2	-0.6	-0.4
Angina	1.8	2.4	5.1	1.9	1.6	1.6	1.6	1.0	1.6	0.8	0.9	1.8	0.8	0.7	1.9	2.0	1.6	1.8	-1.1	-2.2	1.7	1.5
Medication for hormone replacement therapy	1.2	1.3	2.7	-1.3	-0.8	-1.4	-1.5	0.2	0.2	0.2	-0.9	-1.2	-1.2	0.7	-1.0	-0.4	-1.3	-1.3	1.5	1.3	-1.5	-1.7
Vitamin and mineral supplements	1.1	1.5	5.0	-1.2	-0.2	-1.2	-1.3	-0.6	0.0	-1.0	-1.5	-1.8	-1.3	-0.8	-1.4	-0.6	-1.5	-2.2	1.0	1.2	-1.0	-0.9
Supplements: Zinc	0.5	0.6	5.5	-0.2	-0.5	-0.4	-0.9	-0.1	2.3	-0.2	-0.3	0.0	-1.5	-0.6	0.3	-0.6	-0.3	-0.4	0.4	-0.1	-0.5	-0.6
Medication: Co-codamol	0.9	1.1	3.2	-0.9	-1.3	-1.0	-0.8	-0.6	-1.3	-0.9	-1.5	-1.7	-0.3	-0.0	-1.1	-0.4	-1.0	-0.7	1.8	1.3	-0.7	-0.5
Medication: Metformin	1.4	2.0	5.4	1.7	0.9	1.5	1.1	2.3	0.0	1.4	1.2	1.1	1.8	2.2	1.2	1.9	1.5	1.6	0.2	-0.6	1.3	1.0
Diabetes (father)	0.8	1.0	2.4	0.8	1.0	0.8	1.5	0.7	-1.2	0.7	0.5	1.0	1.3	-0.5	0.7	0.4	1.1	0.8	-1.5	-1.2	1.0	1.5
Diabetes (mother)	0.2	0.3	1.5	0.4	-0.5	0.3	0.6	-0.6	0.1	-0.3	-0.8	-0.4	-0.1	-0.1	0.6	-0.5	0.1	0.8	-0.8	-1.2	0.2	0.6
Severe depression (siblings)	0.9	1.0	2.8	1.0	1.2	1.0	0.9	-0.4	0.6	-1.0	-1.7	0.7	0.8	0.7	1.0	0.6	0.9	1.7	-0.6	-0.8	1.3	1.1
Pack years adult smoking proportion	0.4	0.6	3.3	-0.1	-1.8	-0.4	-0.2	-1.3	-0.6	-1.6	-1.0	-0.8	-0.2	-0.3	-0.5	-0.7	-0.2	0.0	0.7	0.5	-0.3	-0.1
Impedance of leg (right)	0.4	1.9	16.9	-0.1	0.5	-0.1	-1.0	-1.4	4.1	-1.1	-1.5	0.3	-2.0	-1.8	0.5	-0.6	-0.5	-0.6	-2.0	-0.9	-0.2	-0.1
Leg fat-free mass (left)	0.2	1.2	9.1	0.4	0.2	0.7	1.5	0.9	-3.0	1.7	1.0	0.5	1.6	0.6	-0.2	0.3	0.9	1.0	-0.4	-0.5	0.1	0.4
Trunk fat percentage	0.6	2.6	19.0	1.1	-0.1	0.7	1.0	2.5	-0.3	2.9	4.4	1.4	1.6	1.6	0.8	0.7	1.4	0.9	-1.2	-0.4	0.4	0.6
Hand grip strength (right)	0.2	0.5	2.0	0.3	-0.2	0.9	0.8	-0.9	-1.4	-0.1	-1.3	0.2	1.1	0.9	0.3	-0.3	0.6	0.8	0.2	-0.1	0.3	0.6
Townsend deprivation index at recruitment	0.9	1.3	3.8	0.9	1.0	1.5	1.1	1.9	-0.2	1.0	1.9	1.4	1.1	-0.2	0.9	0.5	1.0	1.3	-1.0	-0.8	1.2	1.2
Current tobacco smoking	1.6	2.6	5.4	1.9	1.1	2.3	2.2	-0.3	0.1	0.5	-0.9	1.5	1.8	0.5	2.0	0.8	2.0	1.9	-1.6	-2.0	1.9	2.3
Average weekly fortified wine intake	0.2	0.2	1.0	-0.5	-1.0	-0.2	-0.6	0.1	-0.2	0.2	-0.0	-0.7	0.2	0.1	-0.5	-0.4	-0.7	-0.2	0.2	0.7	-0.3	-0.3
Maternal smoking around birth	0.4	0.5	5.4	0.2	1.2	0.9	0.2	-0.7	0.7	0.3	-2.3	-0.1	-0.1	-0.3	-0.1	0.5	0.1	0.1	-0.8	-0.4	0.4	0.4
Fed-up feelings	1.6	3.0	6.9	2.1	1.3	2.2	1.7	0.4	1.4	0.8	-0.5	1.4	1.6	0.7	2.5	1.6	1.7	2.6	-2.2	-1.8	1.8	2.1
Frequency of unenthusiasm / disinterest in last 2 weeks	2.0	2.7	8.0	1.9	1.4	2.1	0.9	1.7	2.8	1.3	-0.9	1.7	0.6	0.8	1.9	1.8	1.5	2.4	-1.4	-1.9	1.5	1.1
Relative age voice broke	1.1	1.8	3.6	1.9	1.6	1.8	1.2	0.6	1.3	0.8	-0.9	1.1	1.2	1.2	1.5	1.5	1.5	1.2	0.0	-1.2	1.6	1.4
Taking other prescription medications	1.1	1.7	4.1	-1.4	-0.6	-1.2	-1.7	1.2	-1.0	0.6	0.7	-1.4	-0.7	0.4	-1.6	-0.7	-1.4	-1.2	1.9	2.0	-1.7	-1.7
Age when periods started (menarche)	0.1	0.3	1.1	0.2	0.3	0.7	-0.2	0.3	0.5	1.0	-0.5	-0.3	0.7	0.6	-0.1	1.1	0.2	-0.1	1.0	0.6	0.7	0.6
Bilateral oophorectomy (both ovaries removed)	0.3	0.4	1.2	0.7	-0.1	0.7	0.4	-0.4	0.4	-0.4	0.1	1.1	0.6	-0.1	0.1	0.2	1.1	1.0	-0.5	-0.0	0.9	0.5
Heel bone mineral density (BMD) T-score, automated (left)	0.4	1.0	4.2	-0.9	-1.7	-0.8	-0.7	0.5	-0.9	-0.0	0.2	-0.8	-0.6	0.7	-1.1	-0.2	-0.8	-1.0	2.1	1.2	-1.0	-1.1
Tinnitus: Yes, but not now, but have in the past	0.4	0.4	1.5	0.7	0.3	0.1	0.7	-0.3	0.3	-1.2	0.1	0.2	-0.1	0.8	0.9	0.7	0.4	0.8	-0.5	-1.0	0.5	0.6
Qualifications: CSEs or equivalent	0.5	0.6	3.2	0.7	1.3	0.5	1.0	0.3	0.1	0.1	1.8	-0.2	0.2	0.2	0.7	0.5	0.6	0.2	-1.1	-1.0	0.7	1.2
Serious illness, injury or assault to yourself	0.5	0.6	3.8	0.2	1.0	0.0	-0.4	1.9	0.2	1.2	1.2	1.0	0.5	0.5	0.8	-0.1	0.4	-0.1	-0.3	0.7	-0.3	-0.8
High blood pressure	1.1	3.0	9.3	1.8	0.4	1.5	2.1	0.5	0.3	1.0	2.7	1.9	1.2	-0.2	2.1	1.6	1.8	1.5	-3.1	-2.3	1.4	2.1
Hayfever, allergic rhinitis or eczema	0.3	0.6	5.3	0.0	-0.7	0.2	0.7	0.9	-2.3	0.9	1.1	0.3	0.9	0.7	-0.2	0.6	0.3	0.1	-0.1	0.3	0.0	0.2
Multivitamins +/- minerals	1.0	1.2	3.5	1.1	0.4	0.8	1.0	1.0	0.4	0.9	1.7	1.8	0.9	0.4	1.2	0.6	1.4	1.9	-1.2	-1.1	0.8	0.8
Stomach or abdominal pain in last month	0.4	0.6	3.0	0.2	1.4	0.9	-0.1	1.7	0.4	1.5	0.3	0.3	0.3	0.7	0.5	1.0	0.2	0.3	-0.1	0.0	0.1	-0.3
Supplements: Glucosamine	0.2	0.3	2.0	0.4	0.1	-0.3	-0.3	0.1	0.9	-0.1	0.6	1.4	0.1	0.1	0.1	0.8	0.5	0.3	0.7	0.6	0.4	-0.4
Diverticular disease/diverticulitis (self-reported)	3.7	4.4	9.5	-2.4	-1.9	-2.1	-2.1	0.4	-1.4	0.1	-1.2	-3.0	-1.7	0.8	-2.4	-1.8	-2.7	-1.7	3.1	2.3	-2.6	-2.8
Medication: Atenolol	1.3	1.6	4.8	1.5	-0.7	0.8	0.8	0.9	1.5	0.3	2.2	1.8	0.6	0.8	1.9	1.3	1.3	1.9	-0.8	-1.4	0.8	0.6
Medication: Levothyroxine sodium	0.2	0.3	1.8	0.3	0.6	0.4	-0.6	0.1	1.4	-0.0	-0.9	0.1	-0.2	1.0	0.5	0.4	-0.2	0.0	-0.2	0.1	-0.1	-0.6
Sitting height	0.5	3.3	8.4	-1.7	-1.9	-1.3	-1.1	-2.5	-1.1	-2.6	-2.9	-2.2	-1.7	-1.2	-2.3	-2.1	-1.7	-1.1	0.7	0.8	-1.9	-1.3
Chronic bronchitis/emphysema (father)	0.5	0.6	2.4	-0.3	-0.1	-0.9	-0.4	-1.4	-1.1	-1.6	-0.5	0.2	0.0	-1.5	-0.1	-1.3	-0.1	-0.2	-0.5	0.7	-0.1	-0.3
High blood pressure (mother)	0.5	0.7	1.7	-1.0	-1.3	-1.0	-0.8	-0.4	0.1	-0.1	-0.7	-0.4	-0.9	-1.2	-0.9	-0.6	-1.1	-1.1	0.7	0.4	-0.9	-1.0
Body mass index (BMI)	1.6	6.8	30.0	2.4	1.2	2.0	2.4	3.4	-1.6	3.5	5.5	2.6	3.5	2.6	1.7	2.6	2.8	2.1	-0.6	-0.9	1.9	1.8
Impedance of leg (left)	0.4	2.0	14.6	-0.5	-0.1	-0.5	-1.3	-1.4	3.8	-1.4	-1.9	-0.3	-2.3	-1.8	0.0	-1.0	-0.9	-1.1	-1.5	-0.5	-0.6	-0.5
Leg predicted mass (left)	0.2	1.1	9.4	0.3	0.2	0.6	1.4	1.0	-3.1	1.7	1.0	0.4	1.6	0.6	-0.3	0.2	0.8	0.9	-0.3	-0.4	0.1	0.4
Trunk fat mass	0.6	2.4	15.3	1.0	0.0	0.8	1.3	2.2	-0.9	2.8	3.9	1.4	1.7	1.3	0.7	0.7	1.4	1.1	-1.3	-0.6	0.3	0.6
Waist circumference	0.8	3.0	15.2	1.4	0.6	1.0	1.6	2.1	-1.7	2.1	3.9	2.2	2.4	1.5	1.1	1.2	2.0	1.2	-1.0	-0.4	1.0	0.7
Number of incorrect matches in round	0.6	1.0	2.8	0.9	0.5	1.2	1.4	-0.3	-1.2	-0.2	-0.6	0.3	1.5	0.6	0.9	0.7	1.0	1.5	-0.7	-0.6	1.5	1.7
Past tobacco smoking	0.3	0.6	2.5	-0.9	-0.4	-0.2	-0.1	0.7	-1.2	1.2	-0.4	-0.1	-0.4	-1.6	-0.9	-1.3	-0.8	-0.4	-0.2	-0.1	-0.8	-0.3
Alcohol usually taken with meals	0.3	0.6	2.7	-0.8	-1.1	-0.7	-0.1	-0.1	-1.6	-0.7	-0.7	-0.5	-0.5	-0.6	-0.7	-1.3	-0.6	-0.4	0.0	0.4	-0.6	-0.7
Nervous feelings	2.1	4.0	9.0	2.4	2.5	2.3	2.3	-0.1	1.5	0.6	-0.8	1.4	1.8	0.6	2.7	1.9	2.1	2.0	-1.7	-2.4	3.0	3.0
Frequency of tenseness / restlessness in last 2 weeks	2.5	3.8	8.8	2.4	0.8	3.0	1.9	1.8	1.1	1.9	-0.2	1.5	2.2	2.3	2.1	2.5	1.9	2.8	-0.7	-1.4	2.4	2.1
Hearing difficulty/problems with background noise	0.8	1.3	2.7	1.1	1.6	1.2	1.2	-0.3	1.3	-0.5	-1.4	1.0	0.2	-0.6	1.2	1.3	1.0	1.0	-1.5	-1.6	1.2	1.3
Hair/balding pattern: Pattern 2	0.8	1.0	4.1	-0.5	-1.0	-0.8	-0.3	-2.0	0.1	-1.7	-1.5	-1.1	-0.9	-0.9	-0.3	-1.6	-0.8	0.5	-1.2	-0.2	-0.6	-0.2
Had menopause	0.9	1.1	3.5	1.3	0.2	1.5	1.3	-0.7	0.1	-0.4	0.1	0.9	1.0	0.1	1.4	1.3	1.2	0.8	-0.6	-1.3	1.4	1.9
Had other major operations	0.5	0.6	1.8	0.6	-0.1	1.0	1.1	0.4	-1.3	0.4	1.0	1.2	1.3	0.6	0.7	0.8	0.9	0.6	-0.3	-0.3	0.5	0.5
Forced vital capacity (FVC)	1.4	5.4	11.3	2.5	3.4	2.8	2.9	-1.5	0.6	-0.7	-1.5	1.9	1.9	-0.1	2.2	1.9	2.4	2.1	-3.3	-2.9	2.9	3.2
Heel bone mineral density (BMD) T-score, automated (right)	0.9	2.1	5.8	-1.7	-2.4	-1.5	-1.2	-0.3	-1.2	-0.4	-0.0	-1.6	-1.4	-0.6	-1.7	-1.1	-1.7	-1.8	1.7	1.7	-1.6	-1.5
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	2.6	-0.8	0.2	-0.6	-0.6	-0.8	0.3	-0.9	-1.6	-0.3	-0.8	-1.3	-0.9	-0.7	-0.6	-0.3	0.1	0.5	-0.4	-0.6
Qualifications: None of the above	0.4	0.9	3.6	-0.5	-1.2	-0.7	-0.8	1.3	-1.0	1.8	1.9	-0.2	0.1	0.2	-0.7	-0.4	-0.2	-0.2	1.0	1.4	-0.8	-0.8
Financial difficulties in last 2 years	0.1	0.2	1.1	0.4	0.3	0.2	0.1	0.4	-0.1	-0.1	0.1	-0.1	0.4	0.6	-0.3	0.6	0.4	0.6	1.0	0.5	0.4	0.1
Mouth/teeth dental problems	0.5	0.7	2.3	0.9	-0.4	1.1	1.2	-0.5	-0.6	-0.8	-0.1	0.3	1.2	0.8	0.5	1.0	0.8	0.9	0.2	-0.4	1.2	1.5
Heart attack	0.5	0.6	2.7	0.8	1.3	0.7	0.1	0.5	1.6	-0.0	0.5	1.4	0.3	-0.1	0.8	0.7	0.8	0.6	-0.2	-0.6	0.8	0.3
Allergy	0.7	1.5	7.3	1.3	2.3	1.1	0.5	-0.4	2.7	-0.2	-0.9	0.7	0.2	-0.2	1.5	0.5	0.9	1.0	-1.5	-1.3	1.4	1.1
Pain all over the body in last month	2.3	2.5	5.3	1.9	2.3	1.1	1.4	0.9	1.9	1.0	0.4	2.0	1.0	0.2	1.7	0.9	1.8	2.0	-2.1	-2.0	1.7	1.5
Diabetes (self-reported)	0.2	0.2	1.3	-0.5	-1.1	-0.5	-0.2	0.0	-0.3	-0.3	0.1	-0.3	-0.4	-0.2	-0.5	-0.6	-0.5	0.1	0.8	0.2	-0.4	-0.7
Hayfever/allergic rhinitis (self-reported)	0.8	1.1	4.3	-0.3	0.1	0.3	-0.7	2.1	-0.6	2.0	0.6	0.5	0.4	1.5	-0.3	0.7	-0.1	-0.3	1.9	1.2	-0.6	-1.3
Medication: Ramipril	1.3	1.6	3.7	-1.5	-1.2	-1.9	-1.8	-0.3	0.4	-0.6	0.9	-1.1	-1.5	-0.7	-1.5	-1.2	-1.5	-1.5	0.5	1.5	-1.5	-1.6
Medication: Simvastatin	0.4	0.6	2.0	1.1	0.3	0.9	0.4	0.2	0.8	0.1	0.5	1.4	0.9	0.3	1.2	0.8	0.9	0.6	-0.2	-0.5	0.8	0.9
Fluid intelligence score	1.3	2.6	5.1	-1.5	-2.2	-1.5	-1.6	-0.7	1.2	-2.0	-2.3	-1.3	-2.1	-1.5	-1.6	-1.5	-1.8	-1.7	0.8	0.8	-1.8	-1.6
Illnesses of siblings	0.6	0.8	2.5	-0.9	-0.2	-0.4	-1.0	0.9	-0.5	1.3	0.1	-1.1	0.2	1.4	-0.8	0.1	-0.7	-1.0	1.4	1.6	-0.8	-0.6
Neuroticism score	1.7	3.5	7.2	2.2	1.8	2.2	1.9	0.7	1.9	1.1	-0.6	1.7	1.3	0.8	2.5	2.1	1.8	2.7	-1.9	-2.2	2.2	2.1
Weight	0.3	1.6	6.9	0.8	-0.0	0.8	1.5	1.4	-2.0	2.0	2.6	1.1	1.7	0.9	0.2	0.6	1.3	1.1	-0.8	-0.5	0.3	0.6
Impedance of arm (right)	0.9	4.4	9.2	-2.2	-2.6	-2.2	-2.4	-2.1	1.3	-2.1	-2.2	-2.0	-3.0	-1.3	-1.8	-2.5	-2.5	-2.0	0.6	1.5	-2.2	-2.1
Arm fat percentage (right)	0.8	3.3	25.0	1.3	0.0	0.8	1.4	2.5	-1.3	2.6	5.0	1.6	2.1	1.9	0.7	1.3	1.7	1.2	-0.7	-0.1	0.6	0.7
Trunk fat-free mass	0.1	0.5	4.9	-0.2	0.1	0.3	1.0	-0.7	-2.2	-0.1	-0.6	-0.0	0.4	-1.0	-0.8	-0.3	0.3	0.4	-0.5	-0.6	-0.3	0.1
Hip circumference	0.5	2.1	9.3	1.4	0.3	1.2	1.6	1.8	-1.3	1.5	3.1	1.7	2.0	1.5	0.7	1.3	1.7	1.3	-0.4	-0.6	0.9	0.9
Time employed in main current job	2.8	3.3	6.4	-2.1	-2.1	-2.5	-2.5	-1.0	0.2	-1.3	0.0	-1.9	-1.9	-1.0	-1.8	-1.7	-2.0	-1.8	1.2	2.3	-2.2	-2.2
Alcohol intake versus 10 years previously	1.8	2.7	7.3	2.0	0.6	1.7	2.1	0.8	0.0	0.7	1.4	1.8	1.6	1.3	2.0	2.1	2.1	2.7	-0.9	-1.6	1.7	1.7
Father’s age at death	0.4	0.6	2.3	-0.8	-0.5	-0.6	-0.3	0.3	-1.5	0.6	1.2	-0.9	0.1	-0.1	-1.1	-0.1	-0.6	-0.9	1.0	1.0	-0.5	-0.4
Worrier / anxious feelings	0.9	1.7	3.5	1.6	0.6	1.5	0.8	1.4	1.6	1.4	-0.1	1.9	1.2	1.1	1.9	1.5	1.4	1.5	-0.6	-0.7	1.5	0.8
Frequency of tiredness / lethargy in last 2 weeks	1.2	2.0	7.4	1.7	1.9	1.3	0.4	0.3	2.7	0.1	-0.8	1.5	0.7	1.1	2.3	1.1	1.2	2.3	-0.9	-1.2	1.4	0.8
Falls in the last year	1.3	1.7	5.2	-1.2	-0.5	-1.4	-1.7	1.4	-0.4	0.8	1.4	-0.5	-0.5	0.1	-1.5	-0.3	-1.0	-1.9	2.3	2.2	-1.2	-1.8
Hair/balding pattern: Pattern 3	0.6	0.8	3.7	-0.6	-1.2	-0.4	-0.9	-0.1	1.9	-0.6	-1.8	-0.6	-1.4	-0.8	-0.5	-0.5	-0.7	-0.7	0.7	-0.1	-0.7	-0.7
Number of live births	0.2	0.3	2.2	0.0	0.4	0.0	0.4	0.6	-1.5	1.1	0.9	-0.5	0.8	0.3	0.2	0.5	-0.0	-0.3	0.4	0.1	0.2	0.5
Forced expiratory volume in 1-second (FEV1)	0.7	2.5	5.3	1.7	2.1	2.0	1.9	-1.1	0.2	-0.1	-1.4	1.6	1.3	-0.4	1.2	1.2	1.7	1.2	-2.3	-1.8	2.0	2.2
Pulse rate	0.4	0.8	4.5	-0.3	-1.3	-0.6	-0.3	-0.0	-1.7	0.5	2.1	0.2	0.7	0.6	-0.7	-0.1	0.1	-0.8	0.4	1.2	-0.5	-0.8
Happiness	1.5	1.8	5.2	1.1	2.0	1.7	1.3	0.0	1.3	-0.4	-1.5	1.0	0.7	-0.2	1.2	0.8	1.0	1.8	-2.3	-1.7	1.5	1.6
Noisy workplace	0.3	0.4	2.8	-0.0	0.8	0.1	-0.1	1.0	-0.5	1.7	1.0	-0.2	0.5	0.6	-0.1	0.1	-0.1	-0.0	-0.5	0.4	-0.3	0.0
Qualifications: A levels/AS levels or equivalent	0.3	0.6	2.1	0.7	0.3	1.1	1.0	-0.5	-0.3	-0.9	-0.6	1.5	0.9	0.2	0.4	0.4	1.0	0.6	-0.9	-0.7	1.1	0.7
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.6	1.9	0.4	0.5	0.6	0.5	-0.1	1.3	-0.5	-0.3	0.9	-0.3	-1.3	1.0	0.4	0.4	0.3	-1.0	-1.4	0.5	0.6
Mouth/teeth dental problems: Dentures	0.8	1.3	3.2	-1.4	-0.4	-1.3	-1.5	0.6	-0.1	0.3	0.3	-0.5	-1.4	-1.4	-1.2	-1.3	-1.3	-1.6	0.3	0.8	-1.8	-1.4
Asthma	1.3	2.5	7.0	-2.0	-1.7	-1.8	-1.1	-0.5	-2.6	-0.7	-0.1	-1.5	-0.9	-0.9	-2.1	-2.0	-1.7	-1.6	1.1	1.5	-2.3	-1.7
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.4	2.9	-0.4	-0.3	0.1	0.8	0.0	-1.7	0.8	0.2	-0.4	0.3	-0.3	-1.0	0.3	-0.2	0.2	-0.7	-0.3	-0.4	0.1
Medication: Cholesterol lowering	0.7	1.1	6.8	1.3	0.1	0.6	0.4	-0.2	2.6	-0.1	1.2	1.7	0.2	0.1	1.7	0.5	1.0	0.8	-0.6	-1.3	0.9	0.7
Depression (self-reported)	1.9	2.2	6.9	-1.4	-2.0	-1.4	-1.9	-1.6	0.1	-2.6	-0.5	-1.7	-1.0	-0.7	-1.3	-1.7	-1.5	-0.9	1.3	1.9	-1.2	-1.3
Medication: Lansoprazole	0.4	0.5	1.2	0.6	0.4	1.1	0.3	0.8	0.3	0.4	-0.3	1.1	1.0	0.6	0.8	0.6	0.6	0.7	0.6	-0.5	0.9	0.8
Prospective memory result	1.1	1.4	5.3	1.0	2.3	1.1	0.3	1.3	1.0	1.9	1.9	1.3	1.0	1.2	0.7	1.0	1.0	0.4	0.3	-0.1	1.2	0.5
Lung cancer (father)	0.2	0.2	1.0	0.4	-0.7	0.2	0.2	-0.6	-0.2	-1.0	0.1	-0.2	0.6	0.8	0.7	0.2	0.4	0.4	0.2	0.2	0.2	0.4
Illnesses of mother	2.6	3.3	6.5	2.2	2.5	2.3	1.9	1.0	0.2	1.1	0.0	1.6	2.0	1.8	2.0	1.4	2.2	2.4	-1.3	-1.7	2.0	2.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.4	3.2	1.1	1.6	1.5	1.5	-1.0	-0.2	-0.4	-1.8	1.0	0.9	-0.5	0.5	0.7	1.1	0.7	-1.7	-1.4	1.4	1.5
Pulse wave Arterial Stiffness index	2.6	3.1	8.5	1.9	2.3	2.0	2.0	0.7	0.8	1.4	0.1	1.9	1.1	-0.0	2.4	1.3	1.7	1.2	-2.9	-2.5	1.6	1.9
Impedance of arm (left)	0.6	2.7	5.9	-1.7	-1.8	-1.6	-1.9	-1.4	1.4	-1.2	-2.2	-1.8	-2.4	-0.8	-1.1	-2.1	-2.0	-1.7	0.2	0.9	-1.7	-1.6
Arm fat mass (right)	0.7	2.9	18.9	1.2	0.2	0.9	1.5	2.3	-1.6	2.5	4.3	1.4	2.2	1.6	0.6	1.3	1.6	1.2	-0.8	-0.4	0.6	0.8
Trunk predicted mass	0.1	0.5	4.8	-0.2	0.2	0.3	1.0	-0.8	-2.2	-0.1	-0.7	-0.0	0.4	-1.1	-0.8	-0.2	0.3	0.5	-0.6	-0.7	-0.3	0.2
Standing height	0.9	8.6	33.4	-3.0	-2.4	-2.1	-1.6	-4.1	-1.0	-3.0	-5.8	-3.1	-3.3	-3.4	-2.9	-4.0	-2.9	-1.8	-0.5	0.3	-3.0	-2.1
Length of working week for main job	1.5	1.7	3.3	1.2	0.7	1.5	1.4	1.5	-0.2	1.8	1.0	1.6	1.2	0.6	1.4	1.4	1.4	1.8	-1.2	-1.4	0.9	1.2
Exposure to tobacco smoke at home	0.4	0.4	3.5	0.1	1.2	-0.0	-0.5	0.5	1.9	-0.1	0.6	0.7	-0.3	-0.8	0.4	-0.3	0.0	-0.0	-0.8	0.1	-0.0	-0.4
Breastfed as a baby	0.2	0.2	1.0	-0.3	-0.4	-0.8	-0.4	-0.4	0.0	-0.3	1.0	0.4	-0.1	-0.3	-0.3	-0.8	0.1	-0.4	0.0	0.3	-0.2	-0.4
Tense / ‘highly strung’	2.5	4.2	8.0	2.4	2.2	2.8	2.3	1.5	0.8	1.3	-0.2	1.6	2.3	1.7	2.3	2.7	2.2	2.2	-0.8	-1.9	2.6	2.6
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.7	3.5	0.1	-1.2	0.2	-1.2	-0.3	1.7	-1.9	-0.9	-0.3	-0.4	0.5	0.5	0.0	-0.4	0.4	1.1	0.7	0.0	-0.3
Hair/balding pattern: Pattern 4	0.5	1.2	3.0	1.1	1.0	0.8	0.8	1.2	0.6	1.7	1.7	1.6	1.2	0.7	0.9	1.1	1.3	1.1	-1.2	-0.7	1.0	0.6
Birth weight of first child	1.2	2.2	5.6	1.4	2.4	1.7	1.9	0.5	0.5	0.8	-1.8	1.3	0.8	-0.5	1.1	1.1	1.4	2.2	-1.7	-2.2	1.6	1.5
Peak expiratory flow (PEF)	0.1	0.3	0.9	0.6	-0.5	0.7	0.2	-0.2	-0.2	0.2	-0.5	0.5	0.7	1.0	0.7	0.2	0.4	0.5	0.6	0.2	0.6	0.4
Pulse wave reflection index	1.4	1.8	4.1	1.4	2.0	1.5	0.9	1.7	1.5	2.0	0.3	1.2	0.5	0.6	1.6	1.6	1.0	0.9	-1.5	-1.5	0.9	1.2
Ever highly irritable/argumentative for 2 days	1.9	2.3	5.2	-1.6	-1.0	-1.6	-1.6	-1.4	0.7	-1.5	-2.0	-1.0	-1.8	-2.1	-1.3	-2.3	-1.7	-1.3	-0.4	0.8	-1.5	-1.7
Loud music exposure frequency	0.9	1.0	2.2	-0.9	-0.8	-0.8	-1.1	0.7	0.3	0.4	-1.2	-1.5	-1.2	0.8	-0.8	-0.4	-1.2	-1.1	1.5	0.8	-1.1	-1.1
Qualifications: O levels/GCSEs or equivalent	0.6	0.9	6.7	0.5	-1.0	0.4	0.5	-1.4	0.9	-2.6	-1.2	0.1	-0.2	0.6	0.9	-0.5	0.5	0.9	0.1	-0.9	1.0	0.8
Mouth/teeth dental problems: Bleeding gums	0.2	0.2	1.5	-0.1	0.2	-0.0	-0.5	-0.3	1.2	0.8	-0.5	-0.1	-0.3	0.3	0.2	-0.0	-0.2	0.2	-0.4	0.2	-0.2	-0.6
Blood clot in the leg (DVT)	1.5	1.9	3.7	-1.8	-1.8	-1.6	-1.3	-0.6	0.0	-1.2	-0.1	-1.0	-1.9	-1.4	-1.6	-1.8	-1.6	-0.9	0.7	0.7	-1.8	-1.9
Medication: Paracetamol	0.1	0.2	2.3	-0.2	0.2	-0.3	-0.3	0.0	0.5	0.4	-1.5	-0.6	-0.5	0.3	0.0	-0.3	-0.6	0.3	-0.4	-0.3	-0.5	-0.2
Headache pain in last month	0.4	0.6	3.9	0.3	0.9	0.5	-0.2	1.3	0.6	2.0	1.2	0.7	0.6	1.0	0.4	0.9	0.5	0.5	-0.3	0.2	0.0	-0.3
Medication for cholesterol, blood pressure or diabetes	0.5	0.9	3.5	-1.0	-0.3	-0.5	-0.5	-0.2	-1.9	0.0	-1.4	-1.2	-0.2	0.1	-1.5	-0.3	-0.7	-0.8	1.3	1.2	-0.7	-0.9
Glaucoma (self-reported)	1.4	1.7	5.9	-1.2	-1.8	-0.8	-1.9	0.8	0.0	0.8	0.2	-0.9	-0.5	0.8	-1.0	-0.4	-1.2	-1.5	2.4	2.2	-1.2	-1.6
Gout (self-reported)	2.2	3.0	9.2	-1.7	0.0	-2.3	-1.6	-2.3	1.0	-3.0	-2.2	-1.8	-2.4	-2.2	-1.0	-1.7	-1.8	-1.6	0.4	0.7	-1.0	-0.8
Hypothyroidism/myxoedema (self-reported)	0.1	0.3	0.8	-0.3	0.7	0.0	-0.5	0.1	0.6	0.4	-0.8	-0.6	-0.7	0.4	-0.1	0.3	-0.9	-0.4	-0.3	-0.1	-0.6	-0.8
Medication: Amlodipine	3.3	4.6	7.5	2.2	2.1	2.1	2.4	2.4	-0.9	2.7	2.4	1.9	2.6	1.8	2.2	1.8	2.7	2.2	-1.7	-1.7	2.0	2.2
Medication: Ventolin 100micrograms inhaler	0.2	0.3	0.9	-0.3	-0.9	-0.6	-0.1	-0.0	-0.1	-0.7	-0.4	0.2	-0.6	0.2	-0.6	-0.8	-0.1	0.1	0.1	-0.3	-0.9	-0.9
Birth weight	0.4	0.9	3.9	0.5	1.4	0.4	1.3	-1.3	-1.6	-0.9	0.7	0.4	0.7	-0.9	0.5	-0.0	0.7	0.5	-2.0	-0.8	0.6	1.0
Chronic bronchitis/emphysema (mother)	0.6	0.7	1.8	-1.1	-0.2	-0.9	-1.0	-0.1	0.3	-0.2	-0.5	-1.1	-1.4	-0.5	-0.6	-0.9	-1.0	-0.8	0.1	0.2	-1.4	-1.1
High blood pressure (siblings)	1.7	2.4	7.9	1.4	1.4	1.3	2.0	-1.4	-0.1	-1.4	-0.8	1.5	1.0	-1.4	1.1	0.9	1.3	1.7	-2.8	-2.3	1.6	1.9
Forced vital capacity (FVC), Best measure	0.8	2.8	6.6	1.6	2.6	2.2	2.2	-1.4	-0.2	-1.2	-1.9	1.2	1.3	-0.4	1.0	1.1	1.6	1.2	-2.3	-2.1	2.0	2.2
Body fat percentage	1.1	4.3	25.6	1.8	0.4	1.3	1.6	2.9	-0.3	3.2	5.1	2.2	2.3	1.8	1.4	1.5	2.1	1.6	-1.5	-0.8	1.1	1.1
Leg fat percentage (right)	1.9	6.8	28.8	2.6	1.7	2.1	2.3	2.9	0.3	3.2	5.4	3.2	2.9	1.8	2.2	2.7	3.0	2.3	-2.0	-1.5	2.0	1.8
Arm fat-free mass (right)	0.2	1.2	5.2	0.8	0.7	1.1	1.7	0.5	-2.3	1.3	0.7	0.8	1.7	0.0	0.3	0.4	1.2	1.2	-1.1	-0.9	0.6	0.9
Exposure to tobacco smoke outside home	0.2	0.3	1.1	0.5	0.3	0.3	0.2	-0.0	-0.4	0.0	0.7	0.6	1.0	0.0	0.7	0.6	0.6	0.4	0.4	0.5	0.9	0.7
Comparative body size at age 10	0.3	0.9	6.8	0.2	1.2	-0.0	0.8	-1.1	-0.1	-0.5	0.3	1.4	-0.1	-1.4	0.6	-0.5	0.6	0.2	-2.6	-1.4	0.0	0.1
Number of full brothers	0.3	0.4	2.0	0.4	-0.1	-0.1	0.9	-0.9	-0.3	-1.4	-0.9	0.1	-0.2	-0.8	-0.4	-0.5	0.6	0.5	-0.1	-0.9	0.4	0.5
Worry too long after embarrassment	2.6	4.3	10.5	2.2	2.9	2.2	2.4	-0.4	1.1	-0.3	-0.4	1.5	1.5	0.2	2.3	1.8	1.9	2.8	-3.2	-2.7	2.5	2.8
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	1.6	0.4	-0.7	0.3	-0.5	1.0	1.3	-0.1	0.6	-0.1	0.1	0.5	0.6	0.5	0.2	0.3	1.2	0.4	0.3	0.1
Wheeze or whistling in the chest in last year	0.4	0.7	5.0	0.1	-0.4	-0.2	-0.2	1.3	-0.4	0.6	2.2	0.2	0.8	1.3	-0.3	-0.1	0.4	0.7	1.2	0.7	-0.3	-0.3
Number of children fathered	0.5	0.5	2.6	0.4	1.2	0.8	0.2	1.0	1.1	1.6	0.4	0.3	-0.1	0.6	0.7	0.8	0.2	0.0	-0.5	-0.9	0.1	0.5
Reason for reducing amount of alcohol drunk: Health precaution	1.8	2.1	3.3	1.8	1.6	1.7	1.5	-0.5	1.1	-0.7	0.7	1.8	1.4	1.4	1.7	1.7	1.7	1.6	-0.9	-1.5	1.8	1.4
Age at first live birth	0.4	0.7	5.2	0.3	-0.3	-0.0	-0.2	-0.9	2.3	-1.2	-1.5	-0.4	-0.7	0.4	0.1	0.3	-0.4	0.3	-0.3	-1.3	0.2	0.5
Pulse wave peak to peak time	2.7	3.2	8.5	-1.9	-2.4	-2.0	-2.0	-0.9	-0.8	-1.6	-0.5	-2.1	-1.2	-0.0	-2.4	-1.4	-1.8	-1.1	2.9	2.5	-1.6	-1.9
Health satisfaction	0.1	0.1	0.6	-0.0	-0.5	0.0	0.0	0.7	-0.1	0.4	0.2	0.0	-0.1	-0.0	-0.3	-0.1	-0.1	0.4	-0.8	0.1	-0.3	-0.3
Shortness of breath walking on level ground	0.2	0.3	1.2	-0.3	-1.1	-0.3	-0.1	-0.0	-0.9	-0.2	0.8	0.3	-0.2	0.2	-0.7	-0.3	-0.1	0.3	0.4	0.4	-0.5	-0.9
Qualifications: College or University degree	0.1	0.4	2.4	0.2	-0.1	0.5	0.0	-1.2	0.2	-1.4	-1.6	0.3	0.4	0.2	0.2	0.1	0.1	-0.2	0.4	0.1	0.6	0.3
Eye problems/disorders: None of the above	2.1	2.5	5.4	1.9	2.3	2.0	2.0	0.3	0.1	0.7	-1.1	1.2	1.7	0.8	1.4	1.4	1.8	1.4	-1.9	-1.6	1.9	1.9
Mouth/teeth dental problems: Loose teeth	0.5	0.6	1.8	-0.7	-0.1	-0.6	-0.7	-1.2	0.1	-1.1	-0.7	-0.5	-0.9	-1.3	-1.0	-0.5	-0.7	-0.9	-0.2	0.7	-0.6	-0.9
Emphysema/chronic bronchitis	0.3	0.3	1.9	0.4	-1.4	0.1	0.2	-0.4	0.3	-0.6	0.2	-0.1	0.2	0.6	0.2	-0.1	0.5	0.6	1.1	0.0	0.5	0.7
Medication for pain relief, constipation, heartburn	0.2	0.4	1.6	0.3	0.1	0.5	-0.3	-0.3	0.8	-0.6	-1.1	-0.3	0.2	1.1	0.2	0.3	0.1	-0.5	1.3	0.7	0.6	-0.1
Neck or shoulder pain in last month	0.9	1.3	2.7	1.1	1.4	1.6	1.6	0.6	-0.4	0.6	0.0	0.2	1.1	1.0	0.9	1.5	1.0	1.1	-1.2	-1.5	1.1	1.5
Medication: Blood pressure	0.8	1.5	5.7	1.2	0.5	0.8	0.8	1.2	1.3	0.9	2.4	1.3	0.8	0.2	1.7	1.2	1.0	0.9	-1.8	-1.2	0.8	1.2
Angina (self-reported)	2.0	2.6	4.9	2.0	1.6	1.7	1.5	1.2	1.8	1.1	1.2	1.9	0.9	0.7	2.0	2.0	1.7	1.9	-1.0	-2.2	1.8	1.6
Migraine (self-reported)	0.3	0.4	1.5	-0.0	0.6	0.1	0.7	-0.8	-0.6	-1.1	-0.9	-0.1	0.1	-1.2	-0.2	-0.1	0.2	0.5	-1.2	-0.6	0.2	0.4
Medication: Ibuprofen	0.2	0.3	1.2	0.1	0.3	0.5	0.8	0.7	-0.7	1.1	0.6	-0.2	0.3	0.3	-0.4	0.6	-0.1	0.3	-0.4	-0.6	-0.2	0.2
Medication: Allopurinol	0.5	0.7	2.8	-0.7	-0.5	-1.1	-0.7	-0.7	1.0	-1.7	-0.9	-1.2	-1.1	-0.5	-0.2	-0.5	-1.0	-0.7	1.1	0.3	-0.2	-0.0
Medication: Omeprazole	2.8	3.4	6.8	-2.3	-2.0	-2.3	-1.9	-0.7	-1.8	-0.9	-0.3	-1.6	-1.6	-1.6	-2.0	-2.6	-1.9	-1.6	0.4	2.0	-2.5	-2.6
Medication: Seretide 50 evohaler	0.2	0.2	1.1	0.2	-0.1	0.6	0.5	0.2	0.0	0.7	-0.1	0.8	0.2	-0.1	0.2	0.5	0.2	1.1	-0.7	-0.7	0.0	0.1
Mean time to correctly identify matches	0.3	0.5	2.5	0.5	1.6	0.6	0.5	0.0	-1.3	-0.1	0.3	0.4	1.1	0.5	0.3	1.0	0.6	0.7	-0.1	0.3	0.8	0.8
Heart disease (mother)	1.2	1.5	5.0	-1.4	-2.2	-0.9	-0.8	-0.5	-0.9	-1.5	-0.4	-1.1	-1.3	-1.0	-1.4	-0.6	-1.5	-1.4	1.1	0.9	-1.5	-1.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.3	1.7	-0.1	-0.7	-0.4	-0.5	-1.3	0.4	-1.3	0.6	0.3	0.0	-0.4	0.2	-0.6	0.1	0.2	-0.1	0.4	-0.1	-0.1
Whole body fat mass	1.0	4.0	20.3	1.7	0.6	1.4	1.8	2.6	-1.0	3.3	4.5	2.0	2.5	1.8	1.2	1.5	2.1	1.6	-1.5	-0.9	1.0	1.1
Leg fat mass (right)	1.4	5.6	23.1	2.2	1.4	1.9	2.2	2.8	-0.8	3.5	4.8	2.7	2.9	1.9	1.7	2.2	2.6	2.0	-1.8	-1.2	1.5	1.4
Arm predicted mass (right)	0.2	1.2	5.5	0.7	0.7	1.2	1.7	0.6	-2.3	1.5	0.6	0.7	1.7	0.0	0.2	0.4	1.2	1.1	-1.0	-1.0	0.5	0.9
Pulse rate, automated reading	0.2	0.7	2.4	-1.0	-0.1	-1.1	-0.5	-0.8	-1.6	-0.3	0.6	-0.7	-0.1	-0.8	-0.8	-1.0	-0.7	-1.4	0.1	0.8	-0.9	-0.7
Alcohol intake frequency.	0.6	1.3	10.7	0.1	-0.6	0.1	-0.6	1.9	1.3	2.3	3.3	1.0	-0.0	0.1	0.7	0.7	0.2	0.2	-0.1	0.2	-0.3	-0.5
Comparative height size at age 10	0.3	1.6	7.3	-1.1	-1.0	-0.9	-0.1	-1.0	-0.4	-0.3	-2.7	-1.1	-1.4	-2.1	-1.0	-2.1	-1.0	-0.5	-1.4	-0.7	-1.4	-0.5
Number of full sisters	0.8	1.0	3.1	1.1	1.1	1.3	1.3	-0.3	-0.1	-0.6	0.6	0.8	0.8	0.3	0.7	0.8	1.1	1.4	-1.2	-1.8	0.8	0.9
Suffer from ‘nerves’	0.7	1.1	2.4	1.2	1.5	1.5	0.9	0.7	0.3	0.4	-0.7	0.1	1.1	0.9	1.1	1.4	0.8	1.1	-0.4	-0.5	1.5	1.5
Overall health rating	1.5	3.2	5.6	1.9	1.6	2.2	2.4	1.3	-0.6	2.0	0.5	1.8	2.0	0.5	1.8	1.9	2.0	2.2	-2.0	-1.8	1.7	2.0
Chest pain or discomfort	0.1	0.2	0.7	-0.1	-0.5	-0.1	-0.7	0.7	0.7	0.3	-0.3	-0.1	-0.3	0.8	-0.2	0.2	-0.2	0.2	0.5	0.4	-0.2	-0.8
Had major operations	0.3	0.4	2.2	-0.0	-1.0	-0.2	-0.3	0.3	-0.0	-0.5	0.1	-0.8	0.0	1.0	-0.8	0.5	-0.3	0.2	1.5	0.8	-0.3	-0.3
Age at last live birth	0.4	0.6	1.9	0.7	0.6	0.4	0.8	-1.0	0.5	-0.9	-0.8	-0.3	0.4	0.3	0.5	0.7	0.3	0.8	-0.5	-1.4	0.8	1.4
Family relationship satisfaction	1.1	1.4	5.7	0.7	1.5	0.9	0.7	-0.1	2.1	-0.5	-1.3	1.1	-0.5	-1.4	1.2	0.1	0.8	0.5	-2.4	-1.9	0.7	0.8
Leg pain on walking	1.2	1.6	2.9	1.4	0.9	1.3	1.1	1.1	1.0	1.7	0.9	1.3	1.3	1.2	1.2	1.3	1.2	1.6	-0.9	-1.0	1.4	1.4
Qualifications: NVQ or HND or HNC or equivalent	0.8	0.9	5.5	-0.7	0.9	-0.8	0.3	0.5	-0.3	0.4	-0.2	-1.0	-1.0	-1.7	-0.2	-1.5	-0.8	-0.3	-2.3	-0.9	-0.9	-0.3
Commuting to job workplace: Car/motor vehicle	0.8	0.9	4.8	-0.5	1.2	-0.5	-0.6	-1.9	1.2	-0.9	-2.2	-0.7	-1.2	-0.7	-0.4	-0.0	-0.7	-0.5	-0.9	-0.3	-0.5	-0.4
Illness, injury, bereavement, stress in last 2 years	2.0	2.4	5.8	-1.8	-1.8	-1.7	-0.9	-1.2	-2.0	-1.8	-0.7	-2.1	-1.1	-0.8	-2.4	-1.3	-1.7	-1.8	1.5	1.4	-1.3	-0.8
Medication: Aspirin	0.8	1.0	2.3	1.0	1.5	0.6	1.1	0.3	0.3	-0.1	1.5	1.5	0.6	-0.3	1.5	0.5	1.1	1.0	-1.4	-1.3	0.8	0.9
Supplements: Vitamin C	1.9	2.2	5.6	1.7	0.7	1.9	0.9	1.3	1.0	1.6	1.9	2.4	1.8	1.5	1.6	1.3	2.1	1.4	-0.2	-0.9	1.4	0.9
Knee pain experienced in last month	0.6	1.0	4.2	0.1	0.5	0.6	-0.4	2.0	-0.0	2.0	1.3	0.3	1.1	2.0	0.1	1.1	0.2	0.3	0.9	1.1	0.0	-0.4
Hypertension (Self-reported)	1.0	2.9	8.1	1.7	0.3	1.6	2.1	1.0	0.2	1.3	2.9	1.8	1.3	0.0	2.0	1.6	1.7	1.4	-2.5	-2.3	1.2	2.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.5	1.6	0.8	0.7	0.5	-0.1	0.6	0.7	0.3	0.7	0.8	0.7	1.3	0.8	1.2	0.6	0.5	0.3	0.3	0.4	-0.1
Illnesses of father: Heart disease	0.8	1.1	2.9	-1.0	-1.4	-1.3	-1.5	-0.0	1.3	0.1	0.3	-0.7	-1.7	-0.5	-0.5	-0.6	-1.2	-1.4	0.6	1.0	-0.9	-1.3
Illnesses of siblings: Diabetes	2.1	2.6	7.8	-1.2	-2.4	-1.9	-0.6	-1.9	0.1	-2.1	-1.6	-1.1	-2.8	-2.8	-1.0	-1.9	-1.4	-0.5	-0.4	-0.9	-1.6	-1.3
Smoking status: Previous	0.3	0.4	1.8	0.4	-0.1	-0.4	-0.4	-0.9	1.3	-1.2	0.3	-0.1	-0.2	1.1	0.4	0.8	0.3	0.1	0.5	0.5	0.4	-0.2
Forced expiratory volume in 1-second (FEV1), predicted	1.5	3.0	5.8	-2.2	-1.4	-1.6	-1.3	-1.1	-2.4	-0.8	-1.7	-2.2	-1.0	-1.2	-2.3	-2.4	-2.0	-2.1	0.7	1.7	-2.1	-1.4
Whole body fat-free mass	0.1	0.6	7.8	-0.1	-0.0	0.3	1.2	0.0	-2.8	0.6	-0.1	0.0	0.8	-0.5	-0.8	-0.2	0.4	0.5	-0.4	-0.5	-0.3	0.2
Leg fat-free mass (right)	0.2	0.9	11.8	-0.2	-0.4	0.2	1.0	0.6	-3.4	1.2	0.3	-0.2	1.2	0.4	-0.8	-0.3	0.3	0.4	0.2	0.0	-0.4	-0.1
Arm fat percentage (left)	1.2	4.6	26.6	1.8	0.6	1.3	1.8	3.0	-1.3	3.1	5.2	1.8	2.7	2.4	1.3	1.7	2.1	1.6	-1.0	-0.5	1.1	1.2
Average weekly red wine intake	2.3	3.4	5.8	2.3	2.0	2.0	2.0	1.1	0.7	1.4	-0.2	2.1	2.0	2.1	2.3	2.1	2.1	1.7	-0.8	-2.0	2.4	1.7
Handedness (chirality/laterality): Left-handed	0.5	0.6	3.4	0.5	1.1	-0.1	0.6	-1.2	0.8	-1.9	-0.7	-0.5	-0.2	0.1	0.5	-0.1	0.3	0.6	0.0	-1.0	0.9	0.8
Mood swings	0.2	0.4	1.6	0.6	0.5	0.6	0.7	0.6	0.4	0.6	0.3	-0.1	0.3	0.0	1.0	0.6	0.3	0.9	-1.3	-0.5	0.5	0.7
Loneliness, isolation	0.5	0.6	1.5	1.1	0.1	0.8	0.3	1.1	0.6	1.1	0.1	0.4	0.9	1.1	0.8	0.7	0.7	1.2	0.2	0.0	1.2	1.0
Long-standing illness, disability or infirmity	0.5	0.7	3.0	-0.9	-1.7	-0.8	-0.8	-0.0	-0.7	-1.1	0.1	-0.9	-0.4	-0.2	-0.7	-0.5	-0.9	0.2	1.2	0.9	-1.1	-0.9
Ever had bowel cancer screening	2.4	2.8	4.8	2.0	1.5	1.9	1.4	1.6	1.6	0.7	2.0	2.2	1.3	1.3	2.0	1.7	1.6	2.1	-1.3	-1.7	1.8	1.6
Diabetes diagnosed by doctor	0.2	0.4	1.5	-0.5	-1.2	-0.9	-0.2	0.2	-0.9	-0.5	0.6	-0.3	-0.3	-0.4	-0.7	-0.8	-0.3	0.1	0.6	0.4	-0.4	-0.7
Ever had stillbirth, spontaneous miscarriage or termination	0.7	0.7	4.8	0.7	0.2	0.3	-0.1	-1.1	1.7	-0.6	-2.2	0.1	0.0	1.3	0.7	0.9	0.4	0.4	0.9	-0.4	0.2	0.1
Friendships satisfaction	2.8	3.5	8.8	2.0	2.5	2.1	1.9	-0.2	2.1	-0.2	-1.5	1.6	1.0	-0.1	2.3	1.3	1.4	1.8	-3.0	-2.1	2.5	2.5
Qualifications: nursing, teaching	0.4	0.6	2.2	-0.4	-1.5	-0.3	-0.5	-1.3	0.3	-1.1	-1.1	0.2	-0.5	-0.6	-0.1	-0.8	-0.3	-1.1	0.9	0.3	0.1	-0.3
Commuting to job workplace: Walk	0.2	0.3	0.8	0.5	-0.3	0.3	0.2	0.9	-0.2	0.1	0.6	0.5	0.9	0.4	0.6	-0.1	0.4	0.8	-0.4	0.2	0.8	0.6
Eye problems/disorders: Cataract	1.6	1.9	5.9	-1.8	-2.4	-1.3	-1.0	-0.0	-1.1	-0.6	1.0	-1.3	-1.4	-1.1	-1.7	-1.3	-1.6	-1.3	1.4	1.0	-1.8	-1.3
Mouth/teeth dental problems: Mouth ulcers	0.2	0.4	2.2	0.5	0.0	0.1	0.1	1.5	-0.2	0.5	1.5	0.8	0.4	0.3	0.4	0.3	0.6	0.1	0.3	0.1	0.5	0.0
Medication for cholesterol	0.2	0.3	1.0	0.5	1.0	0.8	0.5	0.1	0.7	0.3	-0.7	0.2	0.1	0.2	0.6	0.5	0.3	0.2	-0.7	-0.9	0.6	0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.0	2.4	6.2	1.9	0.1	1.7	2.1	-0.3	0.3	-0.1	0.1	1.1	1.5	0.5	2.0	1.3	1.9	2.2	-1.0	-2.3	1.7	2.5
Back pain experienced in last month	0.1	0.2	1.1	-0.0	0.7	0.2	0.3	-0.1	-0.2	0.3	-0.8	0.2	0.2	-0.0	-0.1	-0.3	0.0	0.9	-1.0	-0.2	-0.1	-0.3
Mineral and other dietary supplements	0.4	0.6	1.8	0.5	0.6	1.0	1.0	-1.0	-0.3	-1.2	-0.9	-0.8	0.4	-0.0	0.2	0.3	0.2	0.5	-0.3	-1.1	0.7	1.4
Breast cancer (self-reported)	0.8	0.9	3.1	0.8	0.6	1.1	0.9	0.6	-0.0	0.7	1.6	0.9	1.0	0.2	0.5	1.0	1.0	1.0	-1.8	-1.0	0.7	0.9
Asthma (self-reported)	1.0	1.9	5.9	-1.7	-1.2	-1.6	-1.0	-0.2	-2.4	-0.4	-0.2	-1.2	-0.7	-0.6	-1.8	-1.6	-1.5	-1.5	0.9	1.4	-2.1	-1.7
Osteoporosis (self-reported)	1.1	1.4	4.2	1.2	0.4	1.4	1.2	1.7	-0.4	2.1	0.9	1.3	1.6	1.7	0.7	0.9	1.5	1.1	-0.8	-0.9	0.6	0.7
Osteoarthritis (self-reported)	0.5	0.6	4.3	-0.5	-1.4	-0.5	-0.3	0.3	-2.1	-0.3	0.8	-0.7	0.6	0.6	-0.6	-0.4	-0.4	-0.1	0.7	1.5	-0.4	-0.1
Medication: Aspirin	1.5	1.9	4.1	1.4	1.7	1.0	1.7	0.1	0.4	-0.5	1.4	2.0	0.9	-0.5	1.8	0.7	1.5	1.5	-2.0	-2.0	1.3	1.5
Medication: Gliclazide	0.7	0.8	2.6	0.8	-0.5	0.5	-0.1	1.3	1.2	0.7	1.3	0.2	0.7	1.6	1.0	0.8	0.6	0.7	1.5	0.0	0.9	0.8
Illnesses of father: None of the above (group 1)	0.7	0.9	3.6	0.8	0.5	1.0	0.2	1.6	1.2	1.4	0.7	0.3	0.5	1.9	0.6	1.3	0.6	0.6	1.4	-0.3	0.5	0.3
Smoking status: Current	1.4	2.3	4.9	1.8	1.1	2.2	1.9	-0.2	0.3	0.5	-0.7	1.5	1.7	0.6	2.0	0.9	1.9	1.7	-1.4	-1.8	1.8	2.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.6	3.3	6.7	2.3	1.7	2.4	1.7	-0.2	1.4	0.2	0.6	2.6	2.1	0.7	1.9	2.2	2.3	1.5	-1.7	-1.4	2.6	2.2
Whole body water mass	0.1	0.6	7.5	-0.2	-0.1	0.2	0.9	0.1	-2.7	0.7	-0.0	-0.1	0.7	-0.5	-0.9	-0.3	0.3	0.3	-0.2	-0.3	-0.5	-0.0
Leg predicted mass (right)	0.2	0.9	11.2	-0.1	-0.4	0.2	1.1	0.8	-3.3	1.3	0.4	-0.1	1.2	0.5	-0.8	-0.2	0.4	0.5	0.2	-0.0	-0.4	-0.0
Arm fat mass (left)	0.9	3.7	19.3	1.5	0.7	1.3	1.8	2.6	-1.8	3.0	4.4	1.6	2.6	2.0	0.9	1.6	1.9	1.5	-0.9	-0.6	0.9	1.1
Number of self-reported non-cancer illnesses	0.2	0.4	1.9	-0.5	-1.4	-0.5	-0.8	0.3	-0.5	-0.2	0.4	-0.1	-0.1	0.4	-0.0	-0.3	-0.6	0.0	0.1	1.0	-1.0	-1.0
Average weekly champagne plus white wine intake	1.0	1.4	4.6	-1.2	-1.1	-1.1	-1.6	0.4	-0.0	0.1	-0.4	-0.5	-1.2	0.1	-0.8	-0.9	-1.3	-1.2	2.1	1.5	-1.6	-2.1
Miserableness	0.3	0.5	1.4	0.6	0.8	0.7	0.9	-0.6	-0.0	-0.6	-1.0	0.1	0.3	-0.1	0.8	0.4	0.5	1.0	-1.2	-0.9	0.6	0.9
Guilty feelings	1.0	1.4	3.7	1.3	1.7	1.3	0.4	1.2	1.3	1.2	0.3	0.9	0.8	1.3	1.9	1.4	0.9	1.4	-1.3	-0.5	1.3	1.0
Wears glasses or contact lenses	5.6	6.5	12.2	-2.7	-3.5	-3.1	-2.9	-1.5	-0.5	-1.9	-1.1	-2.7	-2.7	-1.2	-2.6	-2.8	-3.0	-2.8	2.9	2.5	-2.8	-2.8
Ever taken oral contraceptive pill	1.0	1.2	3.9	0.7	1.5	0.3	0.7	-1.0	1.7	-1.8	-0.4	0.4	-0.6	-1.5	0.4	-0.1	0.4	0.8	-2.0	-1.5	0.8	0.9
Hearing aid user	0.3	0.3	1.4	-0.1	-0.2	-0.1	-0.2	-0.1	-1.1	0.0	1.2	0.2	0.4	1.1	-0.2	-0.1	0.0	0.4	0.3	0.8	0.1	-0.5
Mother’s age at death	3.0	3.8	9.3	-2.3	-3.0	-2.2	-1.5	-0.6	-2.4	-1.0	-0.8	-2.7	-1.2	-0.1	-2.0	-2.0	-2.1	-2.2	1.5	2.4	-2.3	-1.9
Financial situation satisfaction	0.6	0.7	3.6	0.9	0.4	0.8	0.2	0.9	1.3	1.2	-0.3	0.5	0.5	1.9	0.6	1.3	0.6	0.6	0.2	0.1	0.7	-0.2
Tinnitus: Yes, now most or all of the time	0.2	0.3	1.0	0.4	0.1	0.5	0.6	-0.5	0.6	0.1	-0.6	0.9	-0.1	-0.3	0.3	0.3	0.2	0.7	-0.9	-1.0	0.4	0.3
Commuting to job workplace: Public transport	0.8	0.9	2.0	-1.0	-1.4	-0.7	-0.7	0.6	-0.8	-0.1	1.4	-0.1	-0.4	-0.5	-1.3	-1.2	-0.5	-1.2	1.0	1.3	-1.0	-1.2
Eye problems/disorders: Glaucoma	1.5	1.7	4.6	-1.2	-1.7	-0.6	-1.9	1.3	1.0	1.6	-0.3	-1.2	-1.3	0.6	-0.9	-0.4	-1.3	-1.4	2.1	1.4	-1.5	-1.6
Medication: Blood pressure	0.3	0.5	3.7	-0.2	-1.6	-0.4	0.1	-0.1	-1.4	-0.4	1.9	-0.3	0.1	-0.6	-0.4	-0.6	-0.1	0.1	-0.2	0.3	-0.3	0.1
Pain type(s) experienced in last month: Hip pain	0.8	1.0	6.2	-1.0	-0.7	-0.9	-0.1	0.4	-2.5	0.1	0.1	-2.0	-0.2	-0.1	-1.3	-0.6	-1.0	-0.6	0.6	0.9	-1.1	-0.4
Supplements: Fish oil (including cod liver oil)	0.3	0.3	1.8	0.3	-0.3	0.0	-0.3	1.1	0.8	0.9	-0.0	1.3	-0.1	0.4	0.9	0.3	0.4	0.3	-0.2	0.1	-0.0	-0.7
High cholesterol (Self-reported)	0.9	1.6	4.4	1.3	0.7	1.1	0.3	1.9	2.1	1.4	1.5	1.9	0.6	1.3	1.6	1.4	1.0	0.8	0.4	-1.0	1.0	0.5
Medication: Bendroflumethiazide	0.6	0.9	6.3	-0.6	-2.5	-0.7	-0.5	-0.3	-1.5	-0.8	1.0	-0.3	-0.1	-0.4	-0.5	-1.2	-0.6	-0.2	-0.2	0.8	-1.1	-0.7
Medication: Paracetamol	0.2	0.3	1.0	-0.1	0.1	-0.2	-0.4	0.7	0.8	1.0	-0.7	-0.3	-0.6	1.0	0.1	-0.1	-0.5	0.2	0.4	-0.2	-0.5	-0.5
Medication: Lisinopril	0.2	0.2	2.0	0.0	-1.4	-0.5	-0.0	-0.2	-0.8	-0.0	0.6	0.2	0.3	-0.2	-0.1	-0.1	0.1	-0.3	0.1	0.8	-0.2	-0.1
Medication: Atorvastatin	0.6	0.8	3.0	0.9	0.3	0.6	1.0	1.4	-0.1	0.2	1.7	0.4	0.9	1.0	0.8	0.9	0.8	1.2	0.5	-0.7	0.9	0.7
Illnesses of father: High blood pressure	0.1	0.2	0.7	0.2	0.0	0.3	0.2	-0.1	0.2	-0.1	-0.6	0.7	0.5	-0.3	0.6	-0.3	0.4	0.8	-0.6	-0.4	0.3	0.3
Alcohol drinker status: Never	0.4	0.5	2.6	-0.0	-0.3	0.1	-0.5	1.4	1.0	1.1	1.6	0.2	-0.2	0.7	0.3	0.4	-0.3	-0.1	-0.2	0.2	-0.4	-0.7
Ever smoked	1.0	1.8	3.6	1.8	1.2	1.3	1.3	-0.6	0.8	-0.8	0.9	0.9	1.5	1.8	1.6	1.9	1.8	1.3	-1.0	-0.8	1.8	1.4
Basal metabolic rate	0.1	0.7	7.4	0.1	0.0	0.4	1.2	0.4	-2.7	1.1	0.6	0.2	1.0	-0.2	-0.6	-0.1	0.6	0.6	-0.5	-0.4	-0.2	0.2
Leg fat percentage (left)	1.5	5.4	26.3	2.3	1.3	1.8	1.9	2.8	0.1	3.0	5.1	2.8	2.7	1.7	1.8	2.3	2.6	1.8	-1.6	-1.1	1.6	1.5
Arm fat-free mass (left)	0.1	0.7	5.6	0.2	0.3	0.6	1.3	0.2	-2.4	0.8	0.6	0.5	1.1	-0.5	-0.4	0.1	0.7	0.7	-0.7	-0.7	0.0	0.5
Number of operations (self-reported)	0.3	0.5	1.2	0.7	-0.5	1.1	1.0	0.9	-0.2	0.5	0.8	1.0	0.8	0.9	0.1	0.5	0.9	0.7	-0.0	-0.7	0.3	0.2
Average weekly beer plus cider intake	0.5	0.7	2.7	-0.4	-0.0	-0.3	0.7	-0.9	-1.1	0.2	-1.6	-1.2	-0.6	-1.5	-0.2	-0.6	-0.4	-0.0	-1.4	-1.0	-0.3	0.5
Irritability	0.2	0.4	1.1	0.5	0.7	0.5	0.6	-1.1	-0.2	-0.9	-1.0	0.8	0.4	0.2	0.4	0.4	0.7	0.6	-0.5	-0.3	0.8	0.2
Risk taking	0.5	0.8	2.4	0.8	1.3	1.3	1.0	0.7	0.6	1.2	-0.8	0.9	0.1	0.1	0.9	0.8	0.6	0.5	-0.9	-1.5	0.5	0.6
Ever had prostate specific antigen (PSA) test	0.8	0.9	5.8	0.6	-1.5	1.0	-0.0	0.8	2.4	0.7	-1.5	0.4	-0.4	0.8	0.5	0.6	-0.1	1.3	0.5	-1.1	0.2	-0.0
Fractured/broken bones in last 5 years	0.2	0.2	1.1	0.2	-0.3	-0.1	-0.1	-0.4	0.7	-0.3	-0.8	0.5	-0.3	-1.1	-0.1	0.2	0.2	0.0	-0.6	-0.6	-0.1	0.3
Age started oral contraceptive pill	1.2	1.5	4.5	1.6	1.5	1.1	1.6	0.2	0.5	0.1	-0.1	1.0	1.0	0.2	1.5	1.2	1.4	2.1	-0.8	-1.7	1.5	1.6
Diastolic blood pressure, automated reading	0.9	2.9	11.5	1.5	1.4	1.2	2.2	-0.8	-0.1	-0.3	1.5	2.0	1.1	-0.7	1.9	0.8	2.0	1.8	-3.4	-2.6	1.4	2.0
Ever depressed for a whole week	0.2	0.3	1.5	-0.1	-0.3	0.0	-0.6	-0.3	0.9	-1.1	-0.8	0.2	-0.4	0.0	-0.0	0.3	-0.0	0.4	1.2	0.5	0.1	-0.2
Unable to work because of sickness or disability	0.2	0.3	1.1	-0.2	-0.0	-0.5	-0.6	0.9	1.0	1.1	0.9	0.4	-0.3	-0.2	0.1	0.0	-0.1	0.2	0.4	0.1	-0.2	-0.6
Commuting to job workplace: Cycle	0.2	0.2	0.9	0.2	0.7	0.2	0.1	0.5	-0.2	0.1	-0.0	-0.2	0.8	1.0	-0.2	0.5	0.1	0.3	0.4	0.5	0.8	0.7
Myopia	1.9	2.7	5.6	-1.9	-2.4	-2.0	-1.4	-1.1	-1.2	-1.5	-0.8	-2.1	-1.6	-1.8	-2.1	-1.4	-1.9	-1.8	1.3	1.4	-1.6	-0.9
Vascular/heart problems diagnosed by doctor	1.1	2.9	8.2	-1.8	-0.4	-1.4	-1.9	-0.6	-0.9	-0.6	-2.9	-2.1	-1.0	0.6	-2.1	-1.4	-1.7	-1.6	2.8	2.4	-1.4	-2.0
Cholesterol lowering medication	0.1	0.1	1.1	0.2	0.0	0.4	0.0	1.0	-0.3	-0.0	0.1	0.3	0.3	0.2	0.0	0.4	0.1	0.2	0.6	0.2	0.2	0.1
Medication: Omeprazole (e.g. Zanprol)	1.9	2.3	5.0	-1.8	-1.9	-1.8	-1.6	-0.5	-2.0	-0.8	0.1	-0.8	-0.9	-1.3	-1.7	-2.0	-1.3	-1.1	0.5	1.9	-2.0	-2.2
Pain experienced in last month	1.8	3.0	10.6	-1.5	-1.5	-1.7	-1.3	-2.6	0.3	-3.3	-2.1	-1.1	-2.0	-2.3	-1.3	-1.8	-1.6	-1.9	0.8	0.4	-1.3	-0.7
Supplements: Calcium	0.3	0.3	3.6	0.1	0.2	-0.3	-0.4	0.2	1.1	0.2	1.9	0.6	0.1	0.2	0.1	-0.3	0.4	0.2	-0.7	0.2	0.0	-0.1
Basal cell carcinoma (self-reported)	0.6	0.7	3.2	1.1	-0.1	1.1	0.7	-0.4	0.7	-0.6	-0.2	0.7	0.5	0.5	0.9	0.6	0.9	1.8	-0.6	-0.8	1.1	1.1
Heart attack/myocardial infarction (self-reported)	0.4	0.5	1.9	0.8	1.2	0.7	0.2	0.3	1.4	-0.2	0.4	1.3	0.4	-0.2	0.8	0.7	0.7	0.7	-0.1	-0.6	0.8	0.4
Deep venous thrombosis (DVT) (self-reported)	2.1	2.8	5.0	-2.1	-2.2	-2.0	-1.7	-0.9	-0.2	-1.5	-0.3	-1.3	-2.0	-1.5	-1.9	-2.1	-1.9	-1.2	1.0	1.2	-2.1	-2.2
Heart disease (siblings)	0.7	0.8	2.3	1.1	0.8	0.5	0.7	0.1	1.2	-1.5	0.4	0.7	0.1	-0.1	1.2	-0.0	0.9	1.4	-0.3	-1.1	1.4	1.1
Alcohol drinker status: Previous	0.2	0.2	1.4	0.3	-0.1	0.5	-0.5	-0.1	1.2	-0.0	0.1	0.5	0.1	-0.1	0.6	0.1	0.2	0.1	-0.1	0.4	0.6	0.3
Pack years of smoking	0.4	0.6	3.4	-0.2	-1.8	-0.4	-0.1	-1.3	-0.8	-1.8	-0.8	-0.8	-0.3	-0.4	-0.5	-0.8	-0.3	-0.0	0.7	0.4	-0.3	0.0
Impedance of whole body	0.4	2.3	7.6	-1.2	-1.2	-1.1	-1.8	-1.5	2.8	-1.4	-2.1	-1.1	-2.5	-1.3	-0.5	-1.8	-1.6	-1.4	-0.7	0.3	-1.2	-1.0
Leg fat mass (left)	1.2	4.8	20.7	2.0	1.2	1.7	2.1	2.7	-1.0	3.3	4.6	2.5	2.8	1.8	1.4	2.0	2.5	1.8	-1.6	-1.1	1.3	1.3
Arm predicted mass (left)	0.1	0.5	5.3	0.0	-0.0	0.3	0.9	0.2	-2.3	0.8	0.6	0.4	0.8	-0.6	-0.6	-0.1	0.6	0.6	-0.6	-0.4	-0.2	0.1