TWAS hub - HAT1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Whole Blood	0.0570	0.0250	0.0014	0.025	NA	0.048	NA	0.030	2.1e-03	NA	2.9e-05	NA	8.1e-04
2	YFS	Blood	0.0708	0.0152	0.0000	0.070	0.069	0.086	0.089	0.087	8.8e-22	1.1e-21	1.3e-26	1e-27	4.3e-27

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Depression (Nagel 2018)	9.5	14.3	18.5	-3.2	-4.3
Depressed Affect (Nagel 2018)	9.3	19.5	24.2	-4.9	-3.8
Neuroticism	8.7	20.9	28.5	-5.3	-3.6
Neuroticism (Nagel 2018)	7.7	18.1	23.1	-4.8	-3.6
Worry (Nagel 2018)	7.5	15.8	23.1	-4.8	-2.9
Neuroticism (2016)	6.7	9.7	10.3	-3.0	-3.2
Frequency of depressed mood in last 2 weeks	6.5	9.1	9.2	-3.0	-3.0
Reaction Time	6.2	11.8	18.4	4.3	2.3
Mean time to correctly identify matches	5.8	11.1	16.5	4.1	2.4
Neuroticism score	5.2	10.9	15.8	-4.0	-2.5
Schizophrenia (2014)	5.1	11.2	12.0	-3.5	-3.2
Fed-up feelings	5.0	9.1	13.2	-3.6	-2.3
Nervous feelings	4.9	9.2	14.5	-3.8	-2.0
Miserableness	4.8	8.3	11.1	-3.3	-2.3
Diastolic blood pressure, automated reading	4.8	14.8	20.5	3.0	4.5
Schizophrenia (2018)	4.6	9.6	10.4	-3.2	-3.0
Bipolar Disorder or Schizophrenia	4.5	11.1	13.2	-3.6	-3.0
Leg fat-free mass (right)	4.4	23.7	26.0	5.1	4.6
Leg predicted mass (right)	4.4	23.6	25.4	5.0	4.7
Leg predicted mass (left)	4.3	22.7	25.2	5.0	4.5
Leg fat-free mass (left)	4.2	22.4	25.2	5.0	4.4
Tinnitus: Yes, but not now, but have in the past	4.1	4.4	7.9	-2.8	-0.9
Heart disease (mother)	4.0	4.9	5.1	-2.3	-2.2
Alzheimer’s Disease (in father)	3.8	4.1	7.9	-0.6	-2.8
Ever used hormone-replacement therapy (HRT)	3.8	4.9	6.2	-2.5	-1.9
Arm predicted mass (right)	3.6	18.4	19.3	4.4	4.2
Suffer from ‘nerves’	3.6	5.7	6.9	-2.6	-2.1
Frequency of unenthusiasm / disinterest in last 2 weeks	3.4	4.6	6.9	-1.5	-2.6
Financial difficulties in last 2 years	3.4	4.6	8.3	2.9	0.9
Basal metabolic rate	3.3	18.5	20.3	4.5	4.1
Frequency of tenseness / restlessness in last 2 weeks	3.2	5.0	8.1	-2.8	-1.4
Arm fat-free mass (right)	3.2	16.3	16.5	4.1	4.0
Whole body fat-free mass	3.2	18.1	18.7	4.3	4.2
Alcohol drinker status: Never	3.2	3.8	4.3	2.1	1.8
Body Mass Index (BMI) (2010)	3.1	4.3	5.8	2.4	1.7
Weight	3.0	14.5	18.3	4.3	3.3
Seen doctor (GP) for nerves, anxiety, tension or depression	3.0	4.6	7.6	-2.8	-1.3
Whole body water mass	3.0	17.4	18.0	4.2	4.1
Leg fat mass (left)	3.0	11.8	16.6	4.1	2.6
BMI	2.9	16.9	22.8	4.8	3.3
Worry too long after embarrassment	2.9	4.9	5.9	-2.4	-2.0
Impedance of leg (right)	2.7	13.1	13.6	-3.7	-3.6
Hearing difficulty/problems with background noise	2.7	4.3	4.6	-2.0	-2.1
Hip circumference	2.7	11.6	15.7	4.0	2.8
Tense / ‘highly strung’	2.7	4.4	7.4	-2.7	-1.2
Loneliness, isolation	2.7	3.8	4.5	-2.1	-1.7
Arm fat-free mass (left)	2.7	13.6	13.9	3.7	3.6
Arm predicted mass (left)	2.7	14.0	14.9	3.9	3.6
Frequency of tiredness / lethargy in last 2 weeks	2.6	4.2	4.8	-1.9	-2.2
Leg fat mass (right)	2.6	9.9	14.9	3.9	2.2
Arm fat mass (left)	2.6	10.6	15.5	3.9	2.4
Diabetes (self-reported)	2.5	3.9	7.0	2.6	0.8
Whole body fat mass	2.5	10.6	16.0	4.0	2.3
Diabetes diagnosed by doctor	2.5	4.1	5.5	2.4	1.6
Systolic blood pressure, automated reading	2.4	7.0	9.6	2.1	3.1
Trunk fat mass	2.4	10.1	15.2	3.9	2.2
Illnesses of father: Heart disease	2.4	3.3	5.2	-1.2	-2.3
Commuting to job workplace: Walk	2.4	2.6	2.7	-1.6	-1.6
Unable to work because of sickness or disability	2.4	3.1	5.8	-2.4	-0.7
Coronary Artery Disease (CAD)	2.3	2.8	3.1	1.8	1.6
Fasting Glucose	2.3	2.7	3.7	1.3	1.9
Body mass index (BMI)	2.3	9.8	13.8	3.7	2.4
Impedance of leg (left)	2.3	11.1	12.1	-3.5	-3.2
Arm fat mass (right)	2.3	9.3	14.3	3.8	2.1
Comparative body size at age 10	2.3	6.4	9.2	3.0	1.9
Number of children fathered	2.3	2.6	3.6	-1.3	-1.9
Deep venous thrombosis (DVT) (self-reported)	2.3	2.9	4.2	2.0	1.3
Breast Cancer	2.2	5.4	10.3	3.2	0.7
Bilateral oophorectomy (both ovaries removed)	2.2	2.5	3.8	-1.1	-2.0
Had menopause	2.2	2.8	4.1	-2.0	-1.2
Trunk fat-free mass	2.2	12.7	13.2	3.5	3.6
Trunk predicted mass	2.2	12.6	13.0	3.5	3.6
Pain type(s) experienced in last month: Hip pain	2.2	2.7	3.1	-1.8	-1.5
Blood clot in the leg (DVT)	2.1	2.8	4.2	2.0	1.2
Forced expiratory volume in 1-second (FEV1), predicted	2.1	4.4	6.8	1.4	2.6
Eye problems/disorders: Glaucoma	2.1	2.4	3.6	-1.9	-1.1
Medication: Bendroflumethiazide	2.1	3.2	3.9	2.0	1.6
Waist Hip Ratio (WHR)	2.0	9.2	13.5	-2.2	-3.7
High blood pressure (siblings)	2.0	2.9	3.8	1.4	1.9
Pulse rate, automated reading	2.0	6.3	7.2	2.7	2.3
Tinnitus: Yes, now most or all of the time	2.0	2.3	2.6	-1.4	-1.6
Medication: Lisinopril	2.0	2.6	2.7	-1.6	-1.6
Impedance of arm (right)	1.9	8.8	11.0	-2.5	-3.3
Ever depressed for a whole week	1.9	2.4	4.2	-2.0	-0.8
Medication: Levothyroxine sodium	1.8	3.1	5.5	2.3	0.8
Chronic bronchitis/emphysema (father)	1.8	2.1	2.6	-1.6	-1.3
Waist circumference	1.8	6.4	10.4	3.2	1.6
Illnesses of siblings	1.8	2.6	2.9	-1.5	-1.7
Supplements: Vitamin C	1.8	2.1	3.7	-0.7	-1.9
HbA1C	1.7	1.9	2.9	-0.9	-1.7
Severe depression (siblings)	1.7	1.9	3.4	-0.6	-1.8
Heel bone mineral density (BMD) T-score, automated (left)	1.7	4.0	5.7	-2.4	-1.5
Arm fat percentage (left)	1.7	6.9	11.9	3.5	1.4
Long-standing illness, disability or infirmity	1.7	2.6	3.6	1.9	1.2
Sensitivity / hurt feelings	1.6	2.8	3.2	-1.8	-1.5
Eye problems/disorders: Diabetes related eye disease	1.6	1.8	2.7	1.6	0.9
Pain all over the body in last month	1.6	1.8	2.0	1.4	1.2
Worrier / anxious feelings	1.6	3.1	4.9	-2.2	-1.1
Headache pain in last month	1.6	2.8	3.3	-1.8	-1.5
Health satisfaction	1.6	2.0	2.2	1.4	1.5
Qualifications: College or University degree	1.6	5.0	6.7	-1.8	-2.6
Impedance of whole body	1.6	8.2	9.7	-2.6	-3.1
Ulcerative Colitis (UC)	1.5	2.8	5.4	-2.3	-0.5
Diverticular disease/diverticulitis (self-reported)	1.5	1.8	2.7	-1.0	-1.6
Serious illness, injury or assault of a close relative in last 2 years	1.5	1.7	1.9	1.4	1.2
Chronic bronchitis/emphysema (mother)	1.5	1.8	3.3	0.5	-1.8
Body fat percentage	1.5	5.8	9.5	3.1	1.4
Bipolar Disorder (2018)	1.4	2.2	3.2	-1.8	-1.1
Ovarian Cancer	1.4	1.9	2.7	-1.6	-1.0
LDL Cholesterol	1.4	2.2	2.4	1.6	1.4
Supplements: Zinc	1.4	1.5	2.0	-1.4	-1.0
Trunk fat percentage	1.4	5.8	9.7	3.1	1.4
Arm fat percentage (right)	1.4	5.5	9.9	3.1	1.1
Hypothyroidism/myxoedema (self-reported)	1.4	2.8	3.4	1.9	1.5
Medication: Ventolin 100micrograms inhaler	1.4	1.8	3.0	-1.7	-0.8
Medication: Omeprazole	1.4	1.6	3.0	-1.7	-0.5
Ever had stillbirth, spontaneous miscarriage or termination	1.4	1.5	1.6	-1.1	-1.3
Leg fat percentage (left)	1.4	5.0	7.8	2.8	1.5
Happiness	1.3	1.5	2.0	-1.4	-1.0
Lung cancer (father)	1.3	1.5	2.2	-0.9	-1.5
Mood swings	1.3	2.4	3.3	-1.8	-1.2
Ever taken oral contraceptive pill	1.3	1.4	1.9	-1.4	-0.9
Qualifications: CSEs or equivalent	1.2	1.6	1.9	1.1	1.4
High blood pressure (mother)	1.2	1.7	2.6	1.6	0.9
Heel bone mineral density (BMD) T-score, automated (right)	1.2	2.8	4.3	-2.1	-1.2
Time employed in main current job	1.2	1.3	2.0	-1.4	0.8
Neck or shoulder pain in last month	1.2	1.7	2.7	-0.8	-1.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.2	1.5	2.9	-1.7	0.2
Illness, injury, bereavement, stress in last 2 years	1.2	1.4	2.5	-1.6	-0.6
Illnesses of father: None of the above (group 1)	1.2	1.5	2.2	0.9	1.5
Risk taking	1.2	1.7	3.4	1.8	0.1
Medication: Ramipril	1.1	1.4	2.8	1.7	0.3
Exposure to tobacco smoke at home	1.1	1.3	2.6	1.6	-0.1
Leg fat percentage (right)	1.1	4.0	6.7	2.6	1.1
Wears glasses or contact lenses	1.1	1.2	2.4	-1.6	0.2
Alzheimer’s Disease (including proxy)	1.0	1.4	2.6	-0.5	-1.6
Lupus	1.0	1.5	2.5	-1.6	-0.7
Smoking Status	1.0	2.5	3.9	2.0	1.0
Serious illness, injury or assault to yourself	1.0	1.3	1.4	1.2	1.1
Pulse rate	1.0	1.7	2.5	1.6	0.9
Impedance of arm (left)	1.0	4.6	6.4	-1.7	-2.5
Pulse wave reflection index	1.0	1.3	1.4	-1.1	-1.2
Ever highly irritable/argumentative for 2 days	1.0	1.2	1.5	-1.2	-0.9
Medication: Paracetamol	1.0	1.7	2.1	-1.4	-1.1
Number of full sisters	1.0	1.2	2.3	-1.5	0.1
Commuting to job workplace: Car/motor vehicle	1.0	1.1	1.2	1.0	1.1
Allergy or Eczema	0.9	2.5	4.3	-2.1	-0.8
Hand grip strength (right)	0.9	2.3	2.9	1.3	1.7
Relative age voice broke	0.9	1.4	1.7	1.1	1.3
Glaucoma (self-reported)	0.9	1.1	2.1	-1.5	0.2
Number of operations (self-reported)	0.9	1.4	2.3	-1.5	-0.7
Medication: Omeprazole (e.g. Zanprol)	0.9	1.0	2.0	-1.4	-0.4
Schizophrenia vs Biploar Disorder	0.8	1.1	1.7	-1.3	-0.7
Hypothyroidism (self reported)	0.8	1.9	2.7	1.6	1.1
Townsend deprivation index at recruitment	0.8	1.2	1.3	-1.1	-1.0
Qualifications: None of the above	0.8	1.8	2.5	1.1	1.6
Prospective memory result	0.8	1.0	1.1	-0.9	-1.0
Mouth/teeth dental problems: Bleeding gums	0.8	1.1	1.5	1.2	0.8
Angina (self-reported)	0.8	1.0	1.8	0.5	1.4
Smoking status: Previous	0.8	1.2	1.5	1.2	1.0
Medication: Gliclazide	0.8	0.9	1.0	1.0	0.9
Basal cell carcinoma (self-reported)	0.8	1.0	1.6	1.3	0.6
Systolic Blood Pressure	0.7	3.6	5.2	1.4	2.3
Type 2 Diabetes (T2D) (2018)	0.7	1.4	2.7	1.6	0.3
Number of incorrect matches in round	0.7	1.1	1.1	-1.1	-1.0
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.8	1.2	-1.1	-0.7
Handedness (chirality/laterality): Left-handed	0.7	0.8	1.0	-1.0	-0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.7	0.8	1.5	-1.2	-0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.4	1.9	-0.9	-1.4
Mother’s age at death	0.7	0.9	1.2	-1.1	0.8
Commuting to job workplace: Cycle	0.7	0.9	1.0	-0.9	1.0
Cholesterol lowering medication	0.7	1.1	1.9	1.4	-0.5
Number of treatments/medications taken	0.6	1.1	1.9	0.5	1.4
Angina	0.6	0.8	1.6	0.1	1.3
Medication for hormone replacement therapy	0.6	0.6	1.1	-1.1	-0.4
Average weekly fortified wine intake	0.6	0.7	1.2	-1.1	0.5
Falls in the last year	0.6	0.8	1.3	1.2	0.4
Number of full brothers	0.6	0.8	1.3	1.2	0.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.8	1.5	-1.2	0.3
Eye problems/disorders: None of the above	0.6	0.7	0.8	0.7	0.9
Medication: Blood pressure	0.6	1.1	1.1	1.1	1.0
Breast cancer (self-reported)	0.6	0.8	1.5	-0.3	1.2
Medication: Aspirin	0.6	0.8	1.4	1.2	0.3
Average weekly beer plus cider intake	0.6	0.9	1.6	-0.5	-1.3
Fractured/broken bones in last 5 years	0.6	0.8	1.1	1.0	0.7
Major Depression (MDD)	0.5	0.6	0.7	-0.8	-0.7
Bipolar Disorder (2011)	0.5	0.4	0.8	-0.3	-0.9
Ulcerative Colitis	0.5	0.8	1.5	-1.2	0.3
Relative age of first facial hair	0.5	1.0	1.9	1.4	0.4
Alcohol usually taken with meals	0.5	0.8	1.2	-0.7	1.1
Medication: Cholesterol lowering	0.5	0.8	1.6	1.2	0.1
Depression (self-reported)	0.5	0.6	0.9	-1.0	-0.6
Standing height	0.5	5.3	6.5	2.0	2.5
Exposure to tobacco smoke outside home	0.5	0.7	1.4	-0.1	-1.2
Wheeze or whistling in the chest in last year	0.5	0.9	1.0	-1.0	-0.9
Migraine (self-reported)	0.5	0.6	0.9	-0.4	1.0
Medication: Ibuprofen	0.5	0.7	0.8	0.9	0.7
Chest pain or discomfort	0.5	0.7	1.4	-0.2	1.2
Had major operations	0.5	0.6	1.1	-1.0	0.2
Leg pain on walking	0.5	0.6	1.0	-0.4	-1.0
Average weekly red wine intake	0.5	0.7	0.8	-0.8	0.9
Irritability	0.5	0.9	1.8	-1.3	0.1
Supplements: Calcium	0.5	0.6	0.7	-0.9	0.6
Irritable Bowel Disease (IBD)	0.4	1.0	1.8	-1.4	-0.4
Age at First Birth	0.4	0.6	0.9	0.6	1.0
HDL Cholesterol	0.4	0.7	1.0	-0.6	-1.0
Heel T-Score	0.4	3.5	6.5	-2.5	-0.7
Hand grip strength (left)	0.4	1.1	1.4	1.2	0.9
Hearing difficulty/problems: Yes	0.4	0.5	0.6	-0.8	-0.7
Other serious medical condition/disability diagnosed by doctor	0.4	0.5	0.9	1.0	0.0
Multivitamins +/- minerals	0.4	0.6	0.8	0.9	0.6
Number of live births	0.4	0.6	0.9	-0.6	1.0
Mouth/teeth dental problems: Loose teeth	0.4	0.5	1.0	-1.0	-0.1
Emphysema/chronic bronchitis	0.4	0.4	0.9	-0.0	0.9
Mineral and other dietary supplements	0.4	0.6	1.1	-1.1	-0.2
Osteoporosis (self-reported)	0.4	0.5	0.9	-0.2	0.9
Hearing aid user	0.4	0.4	0.8	-0.2	-0.9
Financial situation satisfaction	0.4	0.5	0.9	1.0	0.4
High cholesterol (Self-reported)	0.4	0.7	1.3	1.1	-0.4
Myopia	0.4	0.6	1.1	-0.4	-1.1
Alzheimer’s Disease (in mother)	0.3	0.4	0.4	-0.6	-0.6
Crohns Disease (2012)	0.3	0.4	0.6	0.6	0.7
Blood Platelet Count	0.3	3.1	6.2	2.5	-0.1
Height	0.3	5.4	5.4	2.3	2.3
Cardiovascular Disease	0.3	0.9	1.5	1.2	0.6
Maternal smoking around birth	0.3	0.4	0.8	0.9	0.2
Age when periods started (menarche)	0.3	0.7	1.3	1.1	0.0
Hayfever, allergic rhinitis or eczema	0.3	0.5	0.8	-0.9	-0.5
Had other major operations	0.3	0.3	0.6	0.2	0.8
Heart attack	0.3	0.4	0.9	0.9	0.1
Medication: Simvastatin	0.3	0.5	0.8	0.9	-0.4
Fluid intelligence score	0.3	0.7	1.1	0.5	1.1
Father’s age at death	0.3	0.4	0.6	-0.5	0.8
Mouth/teeth dental problems: Dentures	0.3	0.6	0.7	0.6	0.9
Length of working week for main job	0.3	0.4	0.4	0.6	0.6
Qualifications: O levels/GCSEs or equivalent	0.3	0.4	0.7	-0.4	-0.9
Birth weight	0.3	0.7	1.4	0.2	1.2
Medication: Seretide 50 evohaler	0.3	0.4	0.7	0.3	0.8
Alcohol intake frequency.	0.3	0.7	1.1	1.1	0.5
Comparative height size at age 10	0.3	1.8	3.5	0.3	1.9
Overall health rating	0.3	0.7	1.4	1.2	0.1
Family relationship satisfaction	0.3	0.3	0.4	-0.5	-0.6
Medication: Aspirin	0.3	0.4	0.8	0.9	-0.1
Illnesses of siblings: Diabetes	0.3	0.3	0.5	0.5	0.7
Guilty feelings	0.3	0.5	0.8	-0.4	-0.9
Medication: Paracetamol	0.3	0.5	0.8	-0.9	-0.4
Heart attack/myocardial infarction (self-reported)	0.3	0.3	0.7	0.8	-0.0
Alcohol drinker status: Previous	0.3	0.3	0.6	0.0	0.8
Verbal and Numeric Reasoning (VNR)	0.2	0.6	0.6	0.7	0.8
Primary Biliary Cirrhosis	0.2	0.3	0.6	0.2	0.8
Lung FEV1/FVC ratio	0.2	1.0	1.7	0.4	-1.3
Vitamin and mineral supplements	0.2	0.3	0.5	-0.7	-0.1
Medication: Co-codamol	0.2	0.2	0.3	-0.6	0.2
Diabetes (mother)	0.2	0.2	0.4	0.7	-0.2
Pack years adult smoking proportion	0.2	0.3	0.6	0.8	-0.0
Current tobacco smoking	0.2	0.3	0.5	0.7	0.4
Stomach or abdominal pain in last month	0.2	0.2	0.4	-0.6	-0.3
Medication: Atenolol	0.2	0.3	0.5	0.3	-0.7
Sitting height	0.2	1.4	2.9	-0.0	1.7
Past tobacco smoking	0.2	0.3	0.5	-0.7	-0.5
Forced vital capacity (FVC)	0.2	0.9	1.0	1.0	0.9
Mouth/teeth dental problems	0.2	0.3	0.4	-0.5	-0.6
Noisy workplace	0.2	0.2	0.4	-0.6	0.0
Birth weight of first child	0.2	0.4	0.8	-0.2	0.9
Peak expiratory flow (PEF)	0.2	0.6	0.6	-0.8	-0.7
Loud music exposure frequency	0.2	0.2	0.4	-0.1	0.7
Medication for cholesterol, blood pressure or diabetes	0.2	0.4	0.7	-0.8	-0.3
Medication: Amlodipine	0.2	0.2	0.5	-0.0	-0.7
Medication for pain relief, constipation, heartburn	0.2	0.3	0.5	0.2	0.7
Medication: Allopurinol	0.2	0.3	0.6	-0.2	-0.7
Age at last live birth	0.2	0.3	0.4	-0.6	-0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.3	0.5	0.7	0.3
Ever had bowel cancer screening	0.2	0.2	0.4	-0.7	0.2
Back pain experienced in last month	0.2	0.3	0.6	0.8	0.0
Average weekly champagne plus white wine intake	0.2	0.3	0.5	0.1	0.7
Commuting to job workplace: Public transport	0.2	0.2	0.5	0.0	0.7
Supplements: Fish oil (including cod liver oil)	0.2	0.3	0.5	-0.7	0.1
Intelligence (Savage-Jansen 2018)	0.1	0.2	0.4	-0.6	0.3
Mean Putamen Volume	0.1	0.1	0.2	-0.4	-0.1
Rheumatoid Arthritis	0.1	0.2	0.4	-0.6	-0.1
Triglycerides	0.1	0.2	0.4	-0.6	0.0
Type 2 Diabetes (T2D) (2012)	0.1	0.1	0.1	-0.3	0.3
Blood Eosinophil Count	0.1	1.1	1.8	-0.6	-1.3
Blood White Count	0.1	0.9	1.6	1.2	0.5
Lung FVC	0.1	0.4	0.5	-0.4	-0.7
Chronotype (morning person)	0.1	0.2	0.3	-0.4	0.6
Tanning	0.1	1.1	1.1	-1.1	-1.0
Average weekly spirits intake	0.1	0.1	0.2	-0.0	-0.5
Ever had hysterectomy (womb removed)	0.1	0.1	0.1	0.2	0.4
Medication: Metformin	0.1	0.2	0.3	0.6	0.1
Diabetes (father)	0.1	0.2	0.4	-0.0	-0.6
Taking other prescription medications	0.1	0.1	0.1	-0.4	-0.3
High blood pressure	0.1	0.3	0.5	0.3	0.7
Supplements: Glucosamine	0.1	0.1	0.2	0.1	0.4
Ever unenthusiastic/disinterested for a whole week	0.1	0.2	0.3	-0.6	0.0
Allergy	0.1	0.2	0.4	0.6	0.2
Hayfever/allergic rhinitis (self-reported)	0.1	0.2	0.3	-0.6	0.2
Forced expiratory volume in 1-second (FEV1)	0.1	0.2	0.4	0.7	0.1
Asthma	0.1	0.3	0.3	-0.5	-0.6
Medication: Ibuprofen (e.g. Nurofen)	0.1	0.1	0.1	0.3	0.2
Illnesses of mother	0.1	0.1	0.3	0.0	0.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.2	0.3	0.5	0.2
Pulse wave Arterial Stiffness index	0.1	0.1	0.1	0.2	0.3
Breastfed as a baby	0.1	0.2	0.3	0.5	0.2
Hair/balding pattern: Pattern 4	0.1	0.2	0.4	-0.2	-0.6
Gout (self-reported)	0.1	0.2	0.2	-0.4	-0.4
Forced vital capacity (FVC), Best measure	0.1	0.4	0.4	0.6	0.6
Age at first live birth	0.1	0.1	0.3	-0.2	-0.5
Shortness of breath walking on level ground	0.1	0.2	0.2	-0.4	0.5
Hypertension (Self-reported)	0.1	0.4	0.4	0.6	0.6
Eye problems/disorders: Cataract	0.1	0.1	0.2	-0.0	0.4
Mouth/teeth dental problems: Mouth ulcers	0.1	0.1	0.2	-0.1	0.4
Asthma (self-reported)	0.1	0.2	0.2	-0.5	-0.4
Smoking status: Current	0.1	0.1	0.2	0.4	0.1
Number of self-reported non-cancer illnesses	0.1	0.1	0.1	0.3	0.4
Illnesses of father: High blood pressure	0.1	0.1	0.1	0.3	-0.3
Ever smoked	0.1	0.2	0.3	-0.5	-0.2
Age started oral contraceptive pill	0.1	0.1	0.1	-0.4	-0.2
Pain experienced in last month	0.1	0.2	0.2	-0.5	0.4
Heart disease (siblings)	0.1	0.2	0.3	0.5	0.2
Pack years of smoking	0.1	0.2	0.4	0.6	0.2
Crohns Disease (2017)	0.0	0.0	0.1	0.2	0.1
Prostate Cancer	0.0	0.0	0.0	0.1	-0.2
Blood Red Count	0.0	0.4	0.8	0.0	0.9
Respiratory disease	0.0	0.0	0.0	-0.2	-0.1
Hair Pigment	0.0	0.4	0.7	0.8	-0.4
Hair/balding pattern: Pattern 2	0.0	0.0	0.1	0.0	0.3
Alcohol intake versus 10 years previously	0.0	0.1	0.1	0.2	-0.3
Hair/balding pattern: Pattern 3	0.0	0.0	0.0	-0.2	0.2
Qualifications: A levels/AS levels or equivalent	0.0	0.0	0.0	0.0	-0.2
Medication: Lansoprazole	0.0	0.0	0.1	-0.1	0.3
Pulse wave peak to peak time	0.0	0.0	0.0	0.1	-0.2
Qualifications: NVQ or HND or HNC or equivalent	0.0	0.0	0.0	0.1	-0.0
Knee pain experienced in last month	0.0	0.1	0.1	0.2	0.2
Friendships satisfaction	0.0	0.1	0.1	0.3	-0.0
Qualifications: nursing, teaching	0.0	0.0	0.1	-0.0	-0.3
Medication for cholesterol	0.0	0.1	0.1	0.2	0.3
Osteoarthritis (self-reported)	0.0	0.0	0.1	-0.1	-0.2
Medication: Blood pressure	0.0	0.0	0.0	0.0	0.0
Medication: Atorvastatin	0.0	0.0	0.0	0.1	0.0
Ever had prostate specific antigen (PSA) test	0.0	0.0	0.0	0.2	-0.1
Vascular/heart problems diagnosed by doctor	0.0	0.0	0.0	-0.0	-0.1

Hub : Genes

HAT1

Models

Trait associations