TWAS hub - HNRNPA0

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Testis	0.0990	0.0450	0.0031	0.011	NA	0.012	NA	0.007	0.10	NA	0.09400	NA	0.160
2	YFS	Blood	0.0346	0.0161	0.0015	0.000	0.004	0.010	0.005	0.003	0.32	0.012	0.00023	0.0073	0.024

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Pulse rate, automated reading	11.7	37.7	67.5	8.2	-2.8
Mouth/teeth dental problems: Dentures	7.3	12.3	14.7	-3.8	3.1
Pulse rate	6.3	10.6	15.6	4.0	-2.4
Number of incorrect matches in round	4.6	7.6	9.4	-2.4	3.1
Pulse wave reflection index	4.1	5.1	6.9	-2.6	1.8
Supplements: Vitamin C	4.1	4.8	9.5	3.1	-0.3
Number of self-reported non-cancer illnesses	3.5	6.1	10.0	-3.2	1.5
Stomach or abdominal pain in last month	3.4	4.2	6.3	2.5	-1.4
Medication for cholesterol	3.4	5.1	9.5	3.1	0.8
Alzheimer’s Disease (in father)	3.3	3.5	4.8	-2.2	1.5
Number of treatments/medications taken	3.3	6.0	11.9	-3.4	-0.2
Qualifications: None of the above	3.0	6.5	12.8	-3.6	-0.4
Health satisfaction	2.9	3.8	7.2	-2.7	-0.6
Rheumatoid Arthritis	2.8	3.8	6.1	-2.5	1.2
Qualifications: CSEs or equivalent	2.8	3.7	5.7	-2.4	-1.3
Eye problems/disorders: Cataract	2.8	3.3	3.5	-1.9	-1.8
Cholesterol lowering medication	2.7	4.0	7.9	-2.8	-0.0
Vitamin and mineral supplements	2.6	3.5	6.2	-2.5	0.9
Bipolar Disorder (2018)	2.5	3.9	7.8	2.8	-0.2
Happiness	2.5	3.0	5.4	-2.3	-0.7
Pain type(s) experienced in last month: Hip pain	2.5	3.1	4.1	-2.0	1.5
Supplements: Zinc	2.4	2.6	5.1	2.3	0.4
Diastolic blood pressure, automated reading	2.4	7.4	8.2	2.9	-2.6
Verbal and Numeric Reasoning (VNR)	2.3	5.6	11.0	3.3	-0.4
Medication: Blood pressure	2.3	4.4	8.0	-2.8	-0.9
Medication: Paracetamol	2.2	3.7	4.7	-2.2	1.6
Number of children fathered	2.2	2.5	5.0	-2.2	0.2
Leg pain on walking	2.2	2.7	5.1	-2.2	0.6
Qualifications: NVQ or HND or HNC or equivalent	2.2	2.7	5.4	-0.2	-2.3
Alcohol drinker status: Never	2.2	2.6	4.4	0.9	-2.1
Crohns Disease (2012)	2.1	3.4	3.6	-1.9	1.8
Leg fat percentage (right)	2.1	7.5	9.8	-3.1	-2.3
Long-standing illness, disability or infirmity	2.1	3.3	6.2	-2.5	0.6
Miserableness	2.1	3.7	7.3	-2.7	0.1
Leg fat percentage (left)	2.1	7.8	10.2	-3.2	-2.3
Diverticular disease/diverticulitis (self-reported)	2.0	2.4	3.0	-1.3	1.7
Hearing difficulty/problems with background noise	2.0	3.3	6.4	-2.5	0.3
Hayfever/allergic rhinitis (self-reported)	2.0	2.7	4.3	-2.1	1.1
Myopia	2.0	2.9	3.8	1.9	-1.4
Bipolar Disorder or Schizophrenia	1.9	4.6	8.2	2.9	1.0
Prostate Cancer	1.9	2.7	4.2	-1.1	2.1
Taking other prescription medications	1.9	3.0	5.9	-2.4	0.2
Ever unenthusiastic/disinterested for a whole week	1.9	2.3	4.6	-0.2	-2.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.9	2.2	3.9	-0.8	-2.0
Tinnitus: Yes, now most or all of the time	1.9	2.2	2.5	1.4	-1.6
Past tobacco smoking	1.8	3.2	6.3	2.5	-0.4
Fluid intelligence score	1.8	3.7	7.0	2.6	0.7
Forced expiratory volume in 1-second (FEV1)	1.8	6.1	12.2	3.5	-0.3
Wheeze or whistling in the chest in last year	1.8	3.3	3.7	-1.7	-1.9
Overall health rating	1.8	3.9	7.8	-2.8	-0.3
Intelligence (Savage-Jansen 2018)	1.7	5.1	9.6	3.1	-0.8
Crohns Disease (2017)	1.7	3.7	5.5	-2.3	1.4
Other serious medical condition/disability diagnosed by doctor	1.7	2.2	4.2	-0.5	2.0
Medication: Levothyroxine sodium	1.7	3.0	3.5	-1.9	1.5
Medication: Lansoprazole	1.7	2.0	3.9	-2.0	0.2
Illnesses of mother	1.7	2.1	4.1	2.0	-0.5
Migraine (self-reported)	1.7	2.1	4.2	2.1	0.0
Leg fat mass (right)	1.7	6.5	6.6	-2.6	-2.5
Handedness (chirality/laterality): Left-handed	1.7	2.0	3.0	1.0	1.7
Medication: Paracetamol	1.7	2.6	4.3	-2.1	1.0
Fractured/broken bones in last 5 years	1.7	2.2	4.2	2.0	-0.4
Smoking Status	1.6	3.9	6.4	-2.5	-1.2
Heel bone mineral density (BMD) T-score, automated (left)	1.6	3.7	7.1	-0.5	2.7
Body mass index (BMI)	1.6	6.7	8.6	-2.9	-2.2
Forced vital capacity (FVC)	1.6	6.0	11.9	3.5	-0.2
Qualifications: O levels/GCSEs or equivalent	1.6	2.6	5.0	2.2	-0.4
Leg fat mass (left)	1.6	6.4	7.4	-2.7	-2.3
Schizophrenia (2014)	1.5	3.4	4.9	2.2	1.4
Qualifications: College or University degree	1.5	4.8	4.9	2.2	2.2
Smoking status: Previous	1.5	2.2	4.4	-2.1	0.0
Illnesses of father: None of the above (group 1)	1.5	1.8	3.0	0.8	-1.7
Eye problems/disorders: Glaucoma	1.5	1.8	3.5	-0.2	1.9
HbA1C	1.4	1.5	2.0	1.0	1.4
HDL Cholesterol	1.4	2.3	4.6	2.1	-0.1
Primary Biliary Cirrhosis	1.4	2.1	4.1	2.0	-0.2
Multivitamins +/- minerals	1.4	1.8	2.7	1.6	-0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.4	1.7	1.9	-1.2	-1.4
Friendships satisfaction	1.4	1.7	2.9	-1.7	0.8
Allergy or Eczema	1.3	3.4	6.6	-2.6	-0.5
Hypothyroidism (self reported)	1.3	2.9	3.1	-1.8	1.7
Hand grip strength (right)	1.3	3.7	5.7	2.4	-1.3
Hayfever, allergic rhinitis or eczema	1.3	2.9	5.4	-2.3	-0.6
Arm fat mass (right)	1.3	5.2	5.6	-2.2	-2.4
Length of working week for main job	1.3	1.5	2.0	1.0	-1.4
Medication: Amlodipine	1.3	1.9	3.7	0.1	-1.9
Arm fat mass (left)	1.3	5.2	5.8	-2.1	-2.4
Schizophrenia vs Biploar Disorder	1.2	1.5	1.7	-1.3	1.2
Irritable Bowel Disease (IBD)	1.2	3.0	4.5	-2.1	1.2
BMI	1.2	6.9	9.1	-2.2	-3.0
Severe depression (siblings)	1.2	1.4	2.5	1.6	-0.5
Waist circumference	1.2	4.5	7.9	-2.8	-1.1
Pain all over the body in last month	1.2	1.3	1.6	-1.3	1.0
Diabetes (self-reported)	1.2	1.9	2.3	-1.5	1.2
Time employed in main current job	1.2	1.4	1.5	-1.1	1.2
Hypothyroidism/myxoedema (self-reported)	1.2	2.3	2.3	-1.5	1.5
High blood pressure (siblings)	1.2	1.7	3.2	-0.4	-1.8
Medication for pain relief, constipation, heartburn	1.2	2.1	4.2	2.0	-0.1
Heart disease (mother)	1.2	1.5	1.9	-1.4	1.0
Whole body fat mass	1.2	4.9	5.5	-2.1	-2.3
Arm fat percentage (left)	1.2	4.8	5.8	-2.4	-2.0
Diabetes diagnosed by doctor	1.2	2.0	2.3	-1.5	1.4
Wears glasses or contact lenses	1.2	1.4	2.5	-1.6	0.6
Ever depressed for a whole week	1.2	1.5	2.6	-0.6	-1.6
Medication: Omeprazole (e.g. Zanprol)	1.2	1.5	2.5	-0.7	-1.6
Average weekly fortified wine intake	1.1	1.3	1.6	-1.1	1.2
Maternal smoking around birth	1.1	1.5	2.8	-1.7	0.6
Hair/balding pattern: Pattern 2	1.1	1.4	2.7	-0.2	-1.6
Mouth/teeth dental problems	1.1	1.6	1.7	1.3	-1.3
Medication: Ramipril	1.1	1.4	2.7	-1.6	-0.2
Medication: Simvastatin	1.1	1.5	3.1	-1.8	0.0
Illnesses of siblings	1.1	1.5	1.6	1.2	1.3
Arm fat percentage (right)	1.1	4.3	4.6	-2.1	-2.0
Hip circumference	1.1	4.9	5.9	-2.4	-1.9
Father’s age at death	1.1	1.4	2.4	1.5	-0.7
Serious illness, injury or assault of a close relative in last 2 years	1.1	1.3	2.5	1.6	0.2
Exposure to tobacco smoke at home	1.1	1.3	2.2	0.5	1.5
Body fat percentage	1.1	4.4	4.5	-2.1	-2.1
Family relationship satisfaction	1.1	1.3	2.4	-1.5	0.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.1	1.3	2.0	-0.8	1.4
Illnesses of father: High blood pressure	1.1	1.3	1.4	1.2	-1.1
Supplements: Calcium	1.1	1.2	2.4	1.5	0.0
Heart disease (siblings)	1.1	1.4	1.7	-1.3	1.0
Blood Red Count	1.0	9.2	18.5	-4.3	-0.0
Medication: Metformin	1.0	1.4	1.6	-1.1	1.3
Fed-up feelings	1.0	1.8	2.1	-1.5	-1.2
Tinnitus: Yes, but not now, but have in the past	1.0	1.1	2.0	0.3	-1.4
Alcohol usually taken with meals	1.0	1.7	3.3	1.8	0.2
Reason for reducing amount of alcohol drunk: Health precaution	1.0	1.2	2.3	0.2	1.5
Breast cancer (self-reported)	1.0	1.2	1.8	0.8	1.3
Mother’s age at death	1.0	1.3	1.9	1.4	-0.8
Schizophrenia (2018)	0.9	2.0	2.1	1.4	1.4
Hand grip strength (left)	0.9	2.5	3.9	2.0	-1.0
Trunk fat mass	0.9	3.7	4.8	-1.6	-2.2
Heel bone mineral density (BMD) T-score, automated (right)	0.9	2.0	3.7	-0.5	1.9
Heart attack	0.9	1.2	2.3	-1.5	0.3
Qualifications: A levels/AS levels or equivalent	0.9	2.1	4.0	2.0	0.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.9	2.7	4.2	2.0	1.1
Exposure to tobacco smoke outside home	0.9	1.2	1.4	1.2	-1.0
Mouth/teeth dental problems: Loose teeth	0.9	1.0	1.9	-0.4	1.4
Age at last live birth	0.9	1.3	1.6	1.3	-1.0
Qualifications: nursing, teaching	0.9	1.3	2.6	1.6	-0.3
Ever smoked	0.9	1.7	2.6	-1.6	0.9
Heart attack/myocardial infarction (self-reported)	0.9	1.2	2.3	-1.5	0.3
Depressed Affect (Nagel 2018)	0.8	1.6	3.2	-1.8	0.0
Coronary Artery Disease (CAD)	0.8	1.0	1.6	-1.2	-0.7
Trunk fat percentage	0.8	3.1	4.0	-1.5	-2.0
Relative age voice broke	0.8	1.2	1.7	0.9	1.3
Age at first live birth	0.8	1.4	2.8	1.7	-0.3
Medication: Omeprazole	0.8	1.0	1.1	-0.9	-1.0
Basal cell carcinoma (self-reported)	0.8	1.0	1.8	-1.4	0.3
Deep venous thrombosis (DVT) (self-reported)	0.8	1.1	1.5	-1.2	0.8
Pack years of smoking	0.8	1.1	1.3	-1.1	-1.0
Ovarian Cancer	0.7	1.0	1.4	1.2	-0.8
Systolic Blood Pressure	0.7	3.7	6.7	2.6	-0.9
Type 2 Diabetes (T2D) (2018)	0.7	1.3	2.4	-1.6	0.5
Lung FVC	0.7	3.8	3.8	2.0	1.9
Medication: Co-codamol	0.7	0.9	1.3	-1.1	0.6
Weight	0.7	3.5	3.5	-1.9	-1.9
Impedance of arm (right)	0.7	3.5	5.5	2.3	1.2
Impedance of arm (left)	0.7	3.4	4.9	2.2	1.4
Glaucoma (self-reported)	0.7	0.8	1.6	-0.3	1.2
Medication: Ventolin 100micrograms inhaler	0.7	0.9	1.1	-1.1	0.8
Forced vital capacity (FVC), Best measure	0.7	2.6	2.9	1.7	1.5
Commuting to job workplace: Car/motor vehicle	0.7	0.8	1.0	-0.7	1.0
Ever had bowel cancer screening	0.7	0.8	1.2	-1.1	0.6
Ever had prostate specific antigen (PSA) test	0.7	0.8	1.3	-0.5	1.2
Unable to work because of sickness or disability	0.7	0.9	1.6	-0.4	1.3
Lupus	0.6	0.9	0.9	-0.9	-0.9
Ulcerative Colitis	0.6	0.8	1.3	-0.6	1.1
Blood Platelet Count	0.6	6.5	10.0	3.2	-1.7
Sensitivity / hurt feelings	0.6	1.1	1.1	-1.1	1.0
Relative age of first facial hair	0.6	1.2	1.4	1.2	1.0
Pack years adult smoking proportion	0.6	1.0	1.0	-1.0	-1.0
Serious illness, injury or assault to yourself	0.6	0.7	1.4	1.2	0.2
Had other major operations	0.6	0.7	1.4	-0.2	-1.2
Allergy	0.6	1.4	2.8	1.7	0.2
Breastfed as a baby	0.6	0.7	0.9	-0.9	0.8
Peak expiratory flow (PEF)	0.6	1.5	2.9	1.7	0.2
Mouth/teeth dental problems: Bleeding gums	0.6	0.7	1.2	0.5	-1.1
Headache pain in last month	0.6	1.0	1.1	1.0	0.9
Gout (self-reported)	0.6	0.8	1.4	1.2	0.5
Comparative body size at age 10	0.6	1.6	2.5	0.8	-1.6
Illness, injury, bereavement, stress in last 2 years	0.6	0.7	1.2	-1.1	-0.5
Knee pain experienced in last month	0.6	1.0	1.5	-1.2	-0.7
Osteoarthritis (self-reported)	0.6	0.8	1.6	-1.2	0.3
Commuting to job workplace: Public transport	0.6	0.7	1.2	0.5	-1.1
Vascular/heart problems diagnosed by doctor	0.6	1.6	3.1	1.8	0.3
Impedance of whole body	0.6	3.1	4.6	2.2	1.3
Body Mass Index (BMI) (2010)	0.5	0.7	1.4	0.0	-1.2
Fasting Glucose	0.5	0.6	1.2	0.1	-1.1
Respiratory disease	0.5	1.2	2.4	-1.5	0.3
Frequency of depressed mood in last 2 weeks	0.5	0.7	1.4	0.1	-1.2
Angina	0.5	0.7	1.3	-1.1	-0.3
Medication for hormone replacement therapy	0.5	0.6	1.1	0.2	-1.0
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.9	1.3	-0.7	1.1
Worrier / anxious feelings	0.5	0.9	0.9	-1.0	0.9
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.7	1.4	-0.2	1.2
Falls in the last year	0.5	0.6	0.8	-0.7	-0.9
Birth weight of first child	0.5	0.9	1.2	1.1	0.8
Blood clot in the leg (DVT)	0.5	0.7	1.1	-1.1	0.5
Medication: Allopurinol	0.5	0.7	1.4	1.2	0.1
Loneliness, isolation	0.5	0.7	1.3	-1.1	0.3
Guilty feelings	0.5	0.8	1.4	0.5	1.2
Medication: Atorvastatin	0.5	0.6	0.9	-0.5	-1.0
Age started oral contraceptive pill	0.5	0.7	0.9	-0.9	0.7
Ulcerative Colitis (UC)	0.4	0.8	1.3	-1.1	0.5
Bipolar Disorder (2011)	0.4	0.4	0.7	0.8	-0.4
Cardiovascular Disease	0.4	1.2	2.3	0.1	-1.5
Neuroticism	0.4	1.0	2.0	-1.4	-0.2
Chronotype (morning person)	0.4	0.9	1.8	1.4	0.1
Systolic blood pressure, automated reading	0.4	1.2	1.4	1.2	-1.1
Leg fat-free mass (left)	0.4	2.3	3.8	-0.9	-1.9
Townsend deprivation index at recruitment	0.4	0.6	0.7	-0.6	-0.8
Current tobacco smoking	0.4	0.7	1.3	-0.2	-1.1
Age when periods started (menarche)	0.4	1.0	1.6	1.3	0.7
Leg predicted mass (left)	0.4	2.2	3.7	-0.9	-1.9
Tense / ‘highly strung’	0.4	0.6	1.0	0.5	1.0
Chronic bronchitis/emphysema (mother)	0.4	0.4	0.6	0.8	-0.5
Arm fat-free mass (right)	0.4	2.1	2.8	-1.2	-1.7
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	0.8	-0.3	0.9
Emphysema/chronic bronchitis	0.4	0.4	0.9	0.1	-0.9
Angina (self-reported)	0.4	0.5	1.0	-1.0	-0.2
Mean time to correctly identify matches	0.4	0.7	0.9	-0.9	0.8
Back pain experienced in last month	0.4	0.6	1.0	-0.5	-1.0
Asthma (self-reported)	0.4	0.7	1.4	-1.2	-0.2
Osteoporosis (self-reported)	0.4	0.5	0.9	-0.9	0.3
High cholesterol (Self-reported)	0.4	0.6	1.1	-1.1	0.3
Basal metabolic rate	0.4	2.1	3.1	-1.0	-1.8
Arm fat-free mass (left)	0.4	1.9	2.9	-0.9	-1.7
Number of operations (self-reported)	0.4	0.6	1.1	-1.0	-0.3
Risk taking	0.4	0.5	0.7	0.9	-0.6
Arm predicted mass (left)	0.4	1.9	2.9	-1.0	-1.7
Major Depression (MDD)	0.3	0.3	0.6	-0.3	0.7
Breast Cancer	0.3	0.8	0.9	1.0	-0.8
Mean Putamen Volume	0.3	0.3	0.3	0.5	0.6
Triglycerides	0.3	0.5	0.8	0.3	-0.9
Blood White Count	0.3	2.4	4.6	-2.1	-0.4
Heel T-Score	0.3	2.1	4.2	-0.1	2.0
Lung FEV1/FVC ratio	0.3	1.8	3.2	1.8	-0.5
Average weekly spirits intake	0.3	0.3	0.5	0.7	-0.4
High blood pressure	0.3	0.8	1.4	-1.2	-0.5
Impedance of leg (left)	0.3	1.7	2.6	1.6	0.8
Had menopause	0.3	0.3	0.4	0.5	-0.6
Alcohol intake versus 10 years previously	0.3	0.4	0.6	-0.8	-0.4
Noisy workplace	0.3	0.3	0.6	-0.7	0.4
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.4	0.7	-0.0	0.9
Standing height	0.3	2.6	5.3	2.3	0.2
Hair/balding pattern: Pattern 4	0.3	0.8	1.4	-1.2	0.4
Pulse wave peak to peak time	0.3	0.3	0.4	0.6	-0.5
Shortness of breath walking on level ground	0.3	0.4	0.8	0.2	-0.9
Neck or shoulder pain in last month	0.3	0.4	0.6	0.8	0.4
Medication: Seretide 50 evohaler	0.3	0.4	0.6	-0.4	-0.8
Arm predicted mass (right)	0.3	1.8	2.2	-1.2	-1.5
Alcohol intake frequency.	0.3	0.6	1.2	-0.0	-1.1
Hypertension (Self-reported)	0.3	0.8	1.5	-1.2	0.1
Leg fat-free mass (right)	0.3	1.8	3.3	-0.4	-1.8
Commuting to job workplace: Walk	0.3	0.3	0.5	0.1	-0.7
Mineral and other dietary supplements	0.3	0.4	0.8	0.9	-0.0
Leg predicted mass (right)	0.3	1.6	3.1	-0.5	-1.8
Supplements: Fish oil (including cod liver oil)	0.3	0.4	0.7	-0.2	0.9
Average weekly beer plus cider intake	0.3	0.5	0.9	0.0	-1.0
Neuroticism (Nagel 2018)	0.2	0.4	0.5	-0.7	0.6
Alzheimer’s Disease (in mother)	0.2	0.2	0.3	0.5	-0.3
Age at First Birth	0.2	0.3	0.5	0.7	0.4
Neuroticism (2016)	0.2	0.3	0.4	-0.5	-0.7
Blood Eosinophil Count	0.2	1.4	2.8	-1.7	-0.4
Height	0.2	3.0	3.2	1.7	1.8
Diabetes (mother)	0.2	0.3	0.6	-0.8	-0.1
Impedance of leg (right)	0.2	1.2	1.5	1.2	0.9
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.2	0.5	-0.7	-0.1
Bilateral oophorectomy (both ovaries removed)	0.2	0.2	0.3	-0.6	0.4
Supplements: Glucosamine	0.2	0.2	0.3	-0.6	-0.4
Chronic bronchitis/emphysema (father)	0.2	0.3	0.6	-0.1	0.8
Nervous feelings	0.2	0.3	0.5	-0.5	0.7
Financial difficulties in last 2 years	0.2	0.2	0.4	0.6	-0.3
Neuroticism score	0.2	0.4	0.7	-0.8	0.2
Hair/balding pattern: Pattern 3	0.2	0.3	0.5	-0.7	0.1
Number of live births	0.2	0.3	0.3	-0.6	0.4
Asthma	0.2	0.4	0.7	-0.8	-0.4
Pulse wave Arterial Stiffness index	0.2	0.3	0.4	-0.4	0.6
Loud music exposure frequency	0.2	0.3	0.4	-0.6	-0.4
Eye problems/disorders: None of the above	0.2	0.3	0.4	0.3	-0.7
Medication: Ibuprofen	0.2	0.3	0.4	-0.3	0.7
Number of full sisters	0.2	0.2	0.2	0.4	0.5
Illnesses of siblings: Diabetes	0.2	0.2	0.4	-0.6	0.3
Whole body fat-free mass	0.2	1.4	2.2	-0.7	-1.5
Average weekly red wine intake	0.2	0.3	0.5	0.7	0.3
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.3	0.5	0.1	-0.7
Mouth/teeth dental problems: Mouth ulcers	0.2	0.4	0.5	0.5	-0.7
Smoking status: Current	0.2	0.3	0.7	0.1	-0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.3	0.4	0.6	0.5
Whole body water mass	0.2	1.3	2.1	-0.7	-1.4
Ever taken oral contraceptive pill	0.2	0.2	0.2	0.5	0.4
Financial situation satisfaction	0.2	0.2	0.4	-0.1	-0.6
Irritability	0.2	0.3	0.4	-0.4	0.6
Depression (Nagel 2018)	0.1	0.1	0.2	-0.5	0.2
Worry (Nagel 2018)	0.1	0.3	0.4	0.4	0.6
Reaction Time	0.1	0.1	0.2	-0.4	0.3
Type 2 Diabetes (T2D) (2012)	0.1	0.1	0.1	-0.3	-0.2
Waist Hip Ratio (WHR)	0.1	0.6	0.9	0.6	1.0
Hair Pigment	0.1	2.2	4.1	2.0	0.5
Ever used hormone-replacement therapy (HRT)	0.1	0.1	0.2	-0.1	0.5
Sitting height	0.1	0.9	1.2	1.1	-0.7
High blood pressure (mother)	0.1	0.1	0.2	0.4	-0.3
Trunk fat-free mass	0.1	0.8	1.0	-0.8	-1.0
Lung cancer (father)	0.1	0.1	0.3	-0.5	-0.0
Trunk predicted mass	0.1	0.7	1.0	-0.7	-1.0
Ever highly irritable/argumentative for 2 days	0.1	0.1	0.2	0.0	-0.5
Number of full brothers	0.1	0.1	0.1	-0.3	-0.4
Medication: Blood pressure	0.1	0.2	0.2	-0.4	-0.5
Suffer from ‘nerves’	0.1	0.2	0.3	-0.3	-0.6
Chest pain or discomfort	0.1	0.1	0.3	-0.1	0.5
Had major operations	0.1	0.1	0.2	-0.1	0.5
Medication: Aspirin	0.1	0.1	0.1	-0.4	0.1
Medication: Gliclazide	0.1	0.1	0.1	0.3	0.3
Average weekly champagne plus white wine intake	0.1	0.2	0.2	0.5	0.3
Hearing aid user	0.1	0.1	0.2	0.1	0.4
Medication: Bendroflumethiazide	0.1	0.1	0.2	-0.4	0.2
Commuting to job workplace: Cycle	0.1	0.1	0.3	-0.0	0.5
Pain experienced in last month	0.1	0.1	0.2	-0.3	-0.5
Alzheimer’s Disease (including proxy)	0.0	0.1	0.1	-0.3	0.3
LDL Cholesterol	0.0	0.0	0.1	-0.3	-0.1
Tanning	0.0	0.0	0.0	-0.0	0.1
Hearing difficulty/problems: Yes	0.0	0.0	0.0	-0.2	-0.2
Ever had hysterectomy (womb removed)	0.0	0.0	0.1	-0.1	0.3
Eye problems/disorders: Diabetes related eye disease	0.0	0.0	0.0	-0.1	0.1
Diabetes (father)	0.0	0.0	0.0	-0.2	-0.2
Medication: Atenolol	0.0	0.0	0.1	0.2	-0.2
Medication: Cholesterol lowering	0.0	0.0	0.0	0.1	-0.2
Depression (self-reported)	0.0	0.0	0.0	0.2	0.2
Prospective memory result	0.0	0.0	0.0	0.2	-0.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.0	0.0	0.0	-0.0	0.2
Medication for cholesterol, blood pressure or diabetes	0.0	0.1	0.1	-0.1	0.4
Birth weight	0.0	0.0	0.1	0.2	0.0
Worry too long after embarrassment	0.0	0.0	0.0	0.2	-0.1
Comparative height size at age 10	0.0	0.2	0.3	0.3	0.6
Medication: Aspirin	0.0	0.1	0.1	-0.3	-0.0
Illnesses of father: Heart disease	0.0	0.0	0.0	0.1	0.1
Forced expiratory volume in 1-second (FEV1), predicted	0.0	0.1	0.1	-0.1	0.4
Mood swings	0.0	0.0	0.0	0.1	0.2
Medication: Lisinopril	0.0	0.0	0.1	-0.0	-0.3
Alcohol drinker status: Previous	0.0	0.0	0.1	-0.1	-0.3

Hub : Genes

HNRNPA0

Models

Trait associations